Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	AP-2 adaptor complex	AP2A1 AP2A2	4.81e-04	14	49	2	GO:0030122
GeneOntologyCellularComponent	clathrin coat of endocytic vesicle	AP2A1 AP2A2	5.54e-04	15	49	2	GO:0030128
GeneOntologyCellularComponent	extracellular matrix	SULF1 L1CAM FGF10 ADAMTS5 PLG ADAM10 SVEP1	7.93e-04	656	49	7	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	SULF1 L1CAM FGF10 ADAMTS5 PLG ADAM10 SVEP1	8.07e-04	658	49	7	GO:0030312
GeneOntologyCellularComponent	cell surface	SULF1 IGHG4 L1CAM MXRA8 FGF10 ALCAM PLG OCLN ADAM10	9.83e-04	1111	49	9	GO:0009986
GeneOntologyCellularComponent	endolysosome membrane	AP2A1 AP2A2	9.95e-04	20	49	2	GO:0036020
GeneOntologyCellularComponent	clathrin coat of coated pit	AP2A1 AP2A2	1.10e-03	21	49	2	GO:0030132
GeneOntologyCellularComponent	XY body	SMARCC1 DAXX	1.32e-03	23	49	2	GO:0001741
GeneOntologyCellularComponent	collagen-containing extracellular matrix	SULF1 L1CAM FGF10 ADAMTS5 PLG ADAM10	1.43e-03	530	49	6	GO:0062023
GeneOntologyCellularComponent	pore complex	ADAM10 VDAC3	1.69e-03	26	49	2	GO:0046930
GeneOntologyCellularComponent	endolysosome	AP2A1 AP2A2	2.25e-03	30	49	2	GO:0036019
GeneOntologyCellularComponent	clathrin adaptor complex	AP2A1 AP2A2	2.40e-03	31	49	2	GO:0030131
Domain	-	AP2A1 AP2A2	6.47e-06	2	48	2	2.60.40.1030
Domain	AP2_complex_asu	AP2A1 AP2A2	6.47e-06	2	48	2	IPR017104
Domain	Clathrin_a-adaptin_app_sub_C	AP2A1 AP2A2	6.47e-06	2	48	2	IPR003164
Domain	Clathrin_a-adaptin_app_Ig-like	AP2A1 AP2A2	6.47e-06	2	48	2	IPR013038
Domain	Alpha_adaptin_C	AP2A1 AP2A2	6.47e-06	2	48	2	PF02296
Domain	-	AP2A1 AP2A2	3.87e-05	4	48	2	3.30.310.30
Domain	Clathrin_a/coatomer_app_sub_C	AP2A1 AP2A2	3.87e-05	4	48	2	IPR015873
Domain	Coatomer/calthrin_app_sub_C	AP2A1 AP2A2	1.79e-04	8	48	2	IPR009028
Domain	Clathrin_a/b/g-adaptin_app_Ig	AP2A1 AP2A2	2.30e-04	9	48	2	IPR008152
Domain	Alpha_adaptinC2	AP2A1 AP2A2	2.30e-04	9	48	2	PF02883
Domain	Alpha_adaptinC2	AP2A1 AP2A2	2.30e-04	9	48	2	SM00809
Domain	PTX	ADGRG4 SVEP1	2.87e-04	10	48	2	SM00159
Domain	Pentaxin-related	ADGRG4 SVEP1	3.51e-04	11	48	2	IPR001759
Domain	Pentaxin	ADGRG4 SVEP1	3.51e-04	11	48	2	PF00354
Domain	Coatomer/clathrin_app_Ig-like	AP2A1 AP2A2	4.20e-04	12	48	2	IPR013041
Domain	ARM-like	SETX AP2A1 AP2A2 DAXX DAAM1	6.27e-04	270	48	5	IPR011989
Domain	Clathrin/coatomer_adapt-like_N	AP2A1 AP2A2	6.65e-04	15	48	2	IPR002553
Domain	Adaptin_N	AP2A1 AP2A2	6.65e-04	15	48	2	PF01602
Domain	-	ZNF793 ZNF35 ZNF506 ZNF624 ZNF362 ZNF230 ZNF77	1.64e-03	679	48	7	3.30.160.60
Domain	zf-C2H2	ZNF793 ZNF35 ZNF506 ZNF624 ZNF362 ZNF230 ZNF77	1.84e-03	693	48	7	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF793 ZNF35 ZNF506 ZNF624 ZNF362 ZNF230 ZNF77	1.85e-03	694	48	7	IPR013087
Domain	KRAB	ZNF793 ZNF506 ZNF624 ZNF230 ZNF77	2.19e-03	358	48	5	PS50805
Domain	KRAB	ZNF793 ZNF506 ZNF624 ZNF230 ZNF77	2.19e-03	358	48	5	PF01352
Domain	KRAB	ZNF793 ZNF506 ZNF624 ZNF230 ZNF77	2.50e-03	369	48	5	SM00349
Domain	KRAB	ZNF793 ZNF506 ZNF624 ZNF230 ZNF77	2.53e-03	370	48	5	IPR001909
Domain	ZINC_FINGER_C2H2_2	ZNF793 ZNF35 ZNF506 ZNF624 ZNF362 ZNF230 ZNF77	3.44e-03	775	48	7	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF793 ZNF35 ZNF506 ZNF624 ZNF362 ZNF230 ZNF77	3.49e-03	777	48	7	PS00028
Domain	Znf_C2H2-like	ZNF793 ZNF35 ZNF506 ZNF624 ZNF362 ZNF230 ZNF77	3.99e-03	796	48	7	IPR015880
Domain	Znf_C2H2	ZNF793 ZNF35 ZNF506 ZNF624 ZNF362 ZNF230 ZNF77	4.24e-03	805	48	7	IPR007087
Domain	ZnF_C2H2	ZNF793 ZNF35 ZNF506 ZNF624 ZNF362 ZNF230 ZNF77	4.33e-03	808	48	7	SM00355
Domain	Peptidase_M12B_N	ADAMTS5 ADAM10	4.51e-03	39	48	2	IPR002870
Domain	Pep_M12B_propep	ADAMTS5 ADAM10	4.51e-03	39	48	2	PF01562
Domain	DISINTEGRIN_1	ADAMTS5 ADAM10	4.74e-03	40	48	2	PS00427
Domain	Reprolysin	ADAMTS5 ADAM10	4.74e-03	40	48	2	PF01421
Domain	ADAM_MEPRO	ADAMTS5 ADAM10	4.74e-03	40	48	2	PS50215
Domain	DISINTEGRIN_2	ADAMTS5 ADAM10	4.74e-03	40	48	2	PS50214
Domain	Peptidase_M12B	ADAMTS5 ADAM10	4.74e-03	40	48	2	IPR001590
Domain	Disintegrin_dom	ADAMTS5 ADAM10	4.98e-03	41	48	2	IPR001762
Domain	IG_LIKE	IGHG4 L1CAM MXRA8 ALCAM LRIT3	8.31e-03	491	48	5	PS50835
Domain	Ig-like_fold	TRIM2 IGHG4 L1CAM MXRA8 ALCAM LRIT3	9.08e-03	706	48	6	IPR013783
Domain	Ig-like_dom	IGHG4 L1CAM MXRA8 ALCAM LRIT3	9.17e-03	503	48	5	IPR007110
Domain	Ig/MHC_CS	IGHG4 ALCAM	9.76e-03	58	48	2	IPR003006
Pathway	REACTOME_NEF_MEDIATED_CD8_DOWN_REGULATION	AP2A1 AP2A2	1.25e-04	7	35	2	M27044
Pathway	REACTOME_NEF_MEDIATED_CD4_DOWN_REGULATION	AP2A1 AP2A2	2.13e-04	9	35	2	M27011
Pathway	REACTOME_L1CAM_INTERACTIONS	AP2A1 AP2A2 L1CAM ALCAM	2.20e-04	121	35	4	M872
Pathway	REACTOME_RECYCLING_PATHWAY_OF_L1	AP2A1 AP2A2 L1CAM	2.39e-04	49	35	3	M891
Pathway	REACTOME_EPH_EPHRIN_MEDIATED_REPULSION_OF_CELLS	AP2A1 AP2A2 ADAM10	2.69e-04	51	35	3	M27311
Pathway	REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING	AP2A1 AP2A2	3.25e-04	11	35	2	MM14694
Pathway	REACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD2_FZD5_AND_ROR2	AP2A1 AP2A2	3.89e-04	12	35	2	MM15163
Pathway	REACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD2_FZD5_AND_ROR2	AP2A1 AP2A2	4.59e-04	13	35	2	M27415
Pathway	REACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD4	AP2A1 AP2A2	5.35e-04	14	35	2	MM15161
Pathway	REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING	AP2A1 AP2A2	5.35e-04	14	35	2	M10122
Pathway	REACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD4	AP2A1 AP2A2	6.16e-04	15	35	2	M27413
Pathway	REACTOME_VLDLR_INTERNALISATION_AND_DEGRADATION	AP2A1 AP2A2	7.03e-04	16	35	2	M27761
Pathway	REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS	AP2A1 AP2A2	7.03e-04	16	35	2	MM15048
Pathway	REACTOME_VLDLR_INTERNALISATION_AND_DEGRADATION	AP2A1 AP2A2	7.03e-04	16	35	2	MM15506
Pathway	REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS	AP2A1 AP2A2	7.96e-04	17	35	2	M5488
Pathway	REACTOME_LDL_CLEARANCE	AP2A1 AP2A2	8.94e-04	18	35	2	MM15565
Pathway	REACTOME_LDL_CLEARANCE	AP2A1 AP2A2	9.97e-04	19	35	2	M27846
Pathway	REACTOME_PCP_CE_PATHWAY	AP2A1 AP2A2 DAAM1	1.20e-03	85	35	3	MM15041
Pathway	REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS	AP2A1 AP2A2	1.22e-03	21	35	2	M12347
Pathway	REACTOME_EPH_EPHRIN_SIGNALING	AP2A1 AP2A2 ADAM10	1.51e-03	92	35	3	M27201
Pathway	REACTOME_PCP_CE_PATHWAY	AP2A1 AP2A2 DAAM1	1.51e-03	92	35	3	M27322
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	AP2A1 AP2A2 L1CAM GATA2 SMARCC1 FGF10 ALCAM MED13L OCLN ADAM10	1.93e-03	1432	35	10	M509
Pathway	REACTOME_THE_ROLE_OF_NEF_IN_HIV_1_REPLICATION_AND_DISEASE_PATHOGENESIS	AP2A1 AP2A2	2.17e-03	28	35	2	M11362
Pathway	WP_INTERACTIONS_OF_NATURAL_KILLER_CELLS_IN_PANCREATIC_CANCER	GATA2 ADAM10	2.17e-03	28	35	2	M42549
Pubmed	Endocytosis of synaptic ADAM10 in neuronal plasticity and Alzheimer's disease.	AP2A1 AP2A2 ADAM10	9.75e-08	7	50	3	23676497
Pubmed	Antagonistic functions of Dishevelleds regulate Frizzled3 endocytosis via filopodia tips in Wnt-mediated growth cone guidance.	AP2A1 AP2A2 L1CAM	1.55e-06	16	50	3	24305805
Pubmed	Expression of L1-CAM and ADAM10 in human colon cancer cells induces metastasis.	L1CAM ADAM10	2.03e-06	2	50	2	17699774
Pubmed	Attenuation of melanoma invasion by a secreted variant of activated leukocyte cell adhesion molecule.	L1CAM ALCAM	2.03e-06	2	50	2	18483249
Pubmed	Cloning of cDNAs encoding two related 100-kD coated vesicle proteins (alpha-adaptins).	AP2A1 AP2A2	2.03e-06	2	50	2	2564002
Pubmed	Cloning, physical mapping and structural characterization of the human alpha(A)-adaptin gene.	AP2A1 AP2A2	2.03e-06	2	50	2	12036598
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	AP2A1 AP2A2 DOCK11 SYDE2 SMARCC1 NKTR ZNF362 PLG VDAC3	5.58e-06	916	50	9	32203420
Pubmed	L1 is sequentially processed by two differently activated metalloproteases and presenilin/gamma-secretase and regulates neural cell adhesion, cell migration, and neurite outgrowth.	L1CAM ADAM10	6.07e-06	3	50	2	16199880
Pubmed	Clathrin-independent endocytic retrieval of SV proteins mediated by the clathrin adaptor AP-2 at mammalian central synapses.	AP2A1 AP2A2	6.07e-06	3	50	2	35014951
Pubmed	A diacidic motif in human immunodeficiency virus type 1 Nef is a novel determinant of binding to AP-2.	AP2A1 AP2A2	6.07e-06	3	50	2	18032517
Pubmed	AP2 adaptor complex mediates bile salt export pump internalization and modulates its hepatocanalicular expression and transport function.	AP2A1 AP2A2	6.07e-06	3	50	2	22262466
Pubmed	Envelope Glycoprotein Internalization Protects Human and Simian Immunodeficiency Virus-Infected Cells from Antibody-Dependent Cell-Mediated Cytotoxicity.	AP2A1 AP2A2	6.07e-06	3	50	2	26269175
Pubmed	A basic patch on alpha-adaptin is required for binding of human immunodeficiency virus type 1 Nef and cooperative assembly of a CD4-Nef-AP-2 complex.	AP2A1 AP2A2	6.07e-06	3	50	2	19129443
Pubmed	Nuclear translocation and signalling of L1-CAM in human carcinoma cells requires ADAM10 and presenilin/gamma-secretase activity.	L1CAM ADAM10	6.07e-06	3	50	2	19260824
Pubmed	Interaction of Shc with adaptor protein adaptins.	AP2A1 AP2A2	6.07e-06	3	50	2	8617812
Pubmed	The ear of alpha-adaptin interacts with the COOH-terminal domain of the Eps 15 protein.	AP2A1 AP2A2	6.07e-06	3	50	2	8662627
Pubmed	The B cell coreceptor CD22 associates with AP50, a clathrin-coated pit adapter protein, via tyrosine-dependent interaction.	AP2A1 AP2A2	1.21e-05	4	50	2	12646615
Pubmed	Increased plasmin-mediated proteolysis of L1CAM in a mouse model of idiopathic normal pressure hydrocephalus.	L1CAM PLG	1.21e-05	4	50	2	34380733
Pubmed	Disruption of the murine Ap2β1 gene causes nonsyndromic cleft palate.	AP2A1 AP2A2	1.21e-05	4	50	2	20500056
Pubmed	CRMP-2 regulates polarized Numb-mediated endocytosis for axon growth.	AP2A1 L1CAM	1.21e-05	4	50	2	12942088
Pubmed	Association and colocalization of Eps15 with adaptor protein-2 and clathrin.	AP2A1 AP2A2	1.21e-05	4	50	2	9049247
Pubmed	Weak Molecular Interactions in Clathrin-Mediated Endocytosis.	AP2A1 AP2A2	2.02e-05	5	50	2	29184887
Pubmed	A conserved dileucine motif mediates clathrin and AP-2-dependent endocytosis of the HIV-1 envelope protein.	AP2A1 AP2A2	2.02e-05	5	50	2	17108326
Pubmed	Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis.	AP2A1 AP2A2	2.02e-05	5	50	2	9723620
Pubmed	Interaction of HIV-1 Gag with the clathrin-associated adaptor AP-2.	AP2A1 AP2A2	2.02e-05	5	50	2	16139856
Pubmed	Axonal Growth of Midbrain Dopamine Neurons is Modulated by the Cell Adhesion Molecule ALCAM Through Trans-Heterophilic Interactions with L1cam, Chl1, and Semaphorins.	L1CAM ALCAM	2.02e-05	5	50	2	31300520
Pubmed	Endocytic Adaptor Proteins in Health and Disease: Lessons from Model Organisms and Human Mutations.	AP2A1 AP2A2	2.02e-05	5	50	2	31671891
Pubmed	Analysis of the AP-2 adaptor complex and cargo during clathrin-mediated endocytosis.	AP2A1 AP2A2	2.02e-05	5	50	2	15941406
Pubmed	Calcyon, a mammalian specific NEEP21 family member, interacts with adaptor protein complex 3 (AP-3) and regulates targeting of AP-3 cargoes.	AP2A1 AP2A2	3.03e-05	6	50	2	22650988
Pubmed	ADAM10 regulates transcription factor expression required for plasma cell function.	IGHG4 ADAM10	3.03e-05	6	50	2	22880085
Pubmed	Numb expression and asymmetric versus symmetric cell division in distal embryonic lung epithelium.	AP2A1 AP2A2	3.03e-05	6	50	2	22713487
Pubmed	Secreted frizzled related proteins modulate pathfinding and fasciculation of mouse retina ganglion cell axons by direct and indirect mechanisms.	L1CAM ADAM10	3.03e-05	6	50	2	25788689
Pubmed	The mu2 subunit of the clathrin adaptor AP-2 binds to FDNPVY and YppØ sorting signals at distinct sites.	AP2A1 AP2A2	3.03e-05	6	50	2	12121421
Pubmed	Clathrin.	AP2A1 AP2A2	3.03e-05	6	50	2	10966473
Pubmed	Molecular architecture and functional model of the endocytic AP2 complex.	AP2A1 AP2A2	3.03e-05	6	50	2	12086608
Pubmed	HIV-1 Tat enters T cells using coated pits before translocating from acidified endosomes and eliciting biological responses.	AP2A1 AP2A2	3.03e-05	6	50	2	15020715
Pubmed	Alpha-AP-2 directs myosin VI-dependent endocytosis of cystic fibrosis transmembrane conductance regulator chloride channels in the intestine.	AP2A1 AP2A2	4.23e-05	7	50	2	20351096
Pubmed	Clathrin interacts specifically with amphiphysin and is displaced by dynamin.	AP2A1 AP2A2	4.23e-05	7	50	2	9280305
Pubmed	Beta-NAP, a cerebellar degeneration antigen, is a neuron-specific vesicle coat protein.	AP2A1 AP2A2	4.23e-05	7	50	2	7671305
Pubmed	Human immunodeficiency virus Nef induces rapid internalization of the T-cell coreceptor CD8alphabeta.	AP2A1 AP2A2	4.23e-05	7	50	2	16103193
Pubmed	ATRX In-Frame Fusion Neuroblastoma Is Sensitive to EZH2 Inhibition via Modulation of Neuronal Gene Signatures.	SMARCC1 DAXX	4.23e-05	7	50	2	31631027
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	AP2A1 AP2A2 L1CAM MXRA8 SMARCC1 ZNF362 ALCAM OCLN ADAM10	4.80e-05	1203	50	9	29180619
Pubmed	Serine phosphorylation-independent downregulation of cell-surface CD4 by nef.	AP2A1 AP2A2	5.64e-05	8	50	2	2014052
Pubmed	Molecular control of spinal accessory motor neuron/axon development in the mouse spinal cord.	L1CAM ALCAM	5.64e-05	8	50	2	16267219
Pubmed	Decreased synaptic vesicle recycling efficiency and cognitive deficits in amphiphysin 1 knockout mice.	AP2A1 AP2A2	5.64e-05	8	50	2	11879655
Pubmed	Diverse alternative back-splicing and alternative splicing landscape of circular RNAs.	MED13L PRRC2B	5.64e-05	8	50	2	27365365
Pubmed	Accessory protein recruitment motifs in clathrin-mediated endocytosis.	AP2A1 AP2A2	7.25e-05	9	50	2	12057195
Pubmed	Doublecortin interacts with mu subunits of clathrin adaptor complexes in the developing nervous system.	AP2A1 AP2A2	7.25e-05	9	50	2	11591131
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	POLR1F DOCK11 RBMS2 SMARCC1 DAXX INO80 PRRC2B	7.55e-05	724	50	7	36232890
Pubmed	CALM regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature.	AP2A1 AP2A2	9.05e-05	10	50	2	25898166
Pubmed	HIV-1 Nef-induced down-regulation of MHC class I requires AP-1 and clathrin but not PACS-1 and is impeded by AP-2.	AP2A1 AP2A2	9.05e-05	10	50	2	17581864
Pubmed	Haploinsufficiency in the ANKS1B gene encoding AIDA-1 leads to a neurodevelopmental syndrome.	AP2A1 AP2A2	1.10e-04	11	50	2	31388001
Pubmed	Motor axon exit from the mammalian spinal cord is controlled by the homeodomain protein Nkx2.9 via Robo-Slit signaling.	L1CAM ALCAM	1.10e-04	11	50	2	22399681
Pubmed	HIV-1 Assembly at the Plasma Membrane: Gag Trafficking and Localization.	AP2A1 AP2A2	1.10e-04	11	50	2	19802344
Pubmed	MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis.	GATA2 MED13L	1.56e-04	13	50	2	27570068
Pubmed	Multispecies RNA tomography reveals regulators of hematopoietic stem cell birth in the embryonic aorta.	GATA2 SVEP1	1.56e-04	13	50	2	32457985
Pubmed	Interactions of the cytoplasmic domains of human and simian retroviral transmembrane proteins with components of the clathrin adaptor complexes modulate intracellular and cell surface expression of envelope glycoproteins.	AP2A1 AP2A2	1.56e-04	13	50	2	9882340
Pubmed	Association of Trk neurotrophin receptors with components of the cytoplasmic dynein motor.	AP2A1 AP2A2	1.82e-04	14	50	2	11157096
Pubmed	Redundant and nonredundant organismal functions of EPS15 and EPS15L1.	AP2A1 AP2A2	1.82e-04	14	50	2	30692166
Pubmed	APache Is an AP2-Interacting Protein Involved in Synaptic Vesicle Trafficking and Neuronal Development.	AP2A1 AP2A2	1.82e-04	14	50	2	29262337
Pubmed	LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool.	AP2A1 AP2A2	2.10e-04	15	50	2	21307259
Pubmed	HIV-1 envelope glycoprotein biosynthesis, trafficking, and incorporation.	AP2A1 AP2A2	2.40e-04	16	50	2	21762802
Pubmed	Fgf10 regulates transition period of cortical stem cell differentiation to radial glia controlling generation of neurons and basal progenitors.	FGF10 OCLN	2.40e-04	16	50	2	19607792
Pubmed	PICK1 interacts with ABP/GRIP to regulate AMPA receptor trafficking.	AP2A1 AP2A2	2.40e-04	16	50	2	16055064
Pubmed	MicroRNA-140 plays dual roles in both cartilage development and homeostasis.	ADAMTS5 ADAM10	2.72e-04	17	50	2	20466812
Pubmed	SFRPs act as negative modulators of ADAM10 to regulate retinal neurogenesis.	L1CAM ADAM10	2.72e-04	17	50	2	21478884
Pubmed	The role of floor plate contact in the elaboration of contralateral commissural projections within the embryonic mouse spinal cord.	L1CAM ALCAM	3.05e-04	18	50	2	16854408
Pubmed	The epsins define a family of proteins that interact with components of the clathrin coat and contain a new protein module.	AP2A1 AP2A2	3.05e-04	18	50	2	10567358
Pubmed	The frantic play of the concealed HIV envelope cytoplasmic tail.	AP2A1 AP2A2	3.05e-04	18	50	2	23705972
Pubmed	Identification and selected reaction monitoring (SRM) quantification of endocytosis factors associated with Numb.	AP2A1 AP2A2	3.05e-04	18	50	2	23211419
Pubmed	Hedgehog signaling is required for pituitary gland development.	GATA2 FGF10	3.05e-04	18	50	2	11152636
Pubmed	Gene essentiality and synthetic lethality in haploid human cells.	AP2A1 AP2A2 SMARCC1 WDR62	3.32e-04	229	50	4	26472760
Pubmed	Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation.	AP2A1 AP2A2	3.41e-04	19	50	2	31959764
Pubmed	Identification of early-responsive genes correlated to valproic acid-induced neural tube defects in mice.	ZNF35 AP2A2	3.41e-04	19	50	2	15799026
Pubmed	Pericytes are required for blood-brain barrier integrity during embryogenesis.	ALCAM OCLN	3.41e-04	19	50	2	20944625
Pubmed	TSHZ3 deletion causes an autism syndrome and defects in cortical projection neurons.	L1CAM FGF10	4.18e-04	21	50	2	27668656
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	AP2A1 AP2A2 DOCK11 PARP8 WDR62	4.47e-04	446	50	5	24255178
Pubmed	Diverse functions of myosin VI elucidated by an isoform-specific α-helix domain.	AP2A1 AP2A2	4.59e-04	22	50	2	26950368
Pubmed	Tbx2 and Tbx3 regulate cell fate progression of the otic vesicle for inner ear development.	GATA2 FGF10	5.03e-04	23	50	2	36521641
Pubmed	Human immunodeficiency virus type-1 gag and host vesicular trafficking pathways.	AP2A1 AP2A2	5.48e-04	24	50	2	20012524
Pubmed	Continued expression of GATA3 is necessary for cochlear neurosensory development.	GATA2 FGF10	5.48e-04	24	50	2	23614009
Pubmed	Reduced endothelin converting enzyme-1 and endothelin-3 mRNA in the developing bowel of male mice may increase expressivity and penetrance of Hirschsprung disease-like distal intestinal aganglionosis.	L1CAM GATA2	5.48e-04	24	50	2	17131407
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	AP2A1 AP2A2 NEK5 IGHG4 NKTR PRRC2B WDR62 VDAC3	5.50e-04	1321	50	8	27173435
Pubmed	Human immunodeficiency virus (HIV) type-1, HIV-2 and simian immunodeficiency virus Nef proteins.	AP2A1 AP2A2	5.95e-04	25	50	2	20594957
Pubmed	Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80.	L1CAM INO80	5.95e-04	25	50	2	32737294
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	SMARCC1 ZNF362 MED13L PRRC2B	6.01e-04	268	50	4	33640491
Pubmed	Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy.	AP2A1 AP2A2	6.44e-04	26	50	2	24067654
Pubmed	The tale of the long tail: the cytoplasmic domain of HIV-1 gp41.	AP2A1 AP2A2	6.44e-04	26	50	2	23077317
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	SETX AP2A1 AP2A2 SMARCC1 NKTR FLG2 PRRC2B VDAC3	7.02e-04	1371	50	8	36244648
Pubmed	Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.	AP2A1 AP2A2 MXRA8 DAXX ADAM10	7.42e-04	499	50	5	22810586
Pubmed	The AP-3 complex: a coat of many colours.	AP2A1 AP2A2	7.48e-04	28	50	2	9714600
Pubmed	Profiling, Bioinformatic, and Functional Data on the Developing Olfactory/GnRH System Reveal Cellular and Molecular Pathways Essential for This Process and Potentially Relevant for the Kallmann Syndrome.	TRIM2 ADAMTS5	7.48e-04	28	50	2	24427155
Pubmed	Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.	SETX DAXX ZNF362	7.85e-04	125	50	3	32891193
Pubmed	Ring finger protein 12 activates AKT signalling to promote the progression of liver cancer by interacting with EGFR.	AP2A1 AP2A2 IGHG4 FLG2	7.96e-04	289	50	4	37132043
Pubmed	Baf60c is essential for function of BAF chromatin remodelling complexes in heart development.	SMARCC1 FGF10	8.02e-04	29	50	2	15525990
Pubmed	The essential player in adipogenesis GRP78 is a novel KCTD15 interactor.	AP2A1 AP2A2	8.02e-04	29	50	2	29665387
Pubmed	The transcription factor gene Nfib is essential for both lung maturation and brain development.	L1CAM FGF10	8.59e-04	30	50	2	15632069
Pubmed	Genome-wide analysis of chromosomal alterations in patients with esophageal squamous cell carcinoma exposed to tobacco and betel quid from high-risk area in India.	SULF1 FGF10	8.59e-04	30	50	2	20083228
Pubmed	FCH domain only-2 organizes clathrin-coated structures and interacts with Disabled-2 for low-density lipoprotein receptor endocytosis.	AP2A1 AP2A2	9.17e-04	31	50	2	22323290
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	AP2A1 AP2A2 PARP8 SMARCC1 ALCAM USPL1 PRRC2B VDAC3	9.74e-04	1442	50	8	35575683
Cytoband	9q34.13	SETX PRRC2B	2.41e-04	21	50	2	9q34.13
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF793 ZNF35 ZNF506 ZNF624 ZNF362 ZNF230 ZNF77	6.51e-04	718	38	7	28
ToppCell	11.5-Distal-Mesenchymal-Mesenchyme_SERPINF1-high\|Distal / Age, Tissue, Lineage and Cell class	DOCK11 SULF1 ALCAM ADAMTS5 RIC3	1.46e-06	173	50	5	6989c9cebcd81eccceac7e5a86152676ee959386
ToppCell	facs-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF1 MXRA8 FGF10 ADAMTS5 SVEP1	2.14e-06	187	50	5	90a1078b0303799fba5d2ca4fa12076fd75b78b1
ToppCell	facs-Pancreas-Exocrine-24m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF1 MXRA8 FGF10 ADAMTS5 SVEP1	2.14e-06	187	50	5	0f90bce2087aecfdbb377e6f46c6e468efbb6e28
ToppCell	facs-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF1 MXRA8 FGF10 ADAMTS5 SVEP1	2.14e-06	187	50	5	76c957b2976d38adb45e07bcf96c689442e1fc20
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D175\|Adult / Lineage, Cell type, age group and donor	SULF1 MXRA8 ADAMTS5 ADGRG4 SVEP1	2.31e-06	190	50	5	7dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell\|Adult / Lineage, Cell type, age group and donor	SULF1 MXRA8 ADAMTS5 ADGRG4 SVEP1	2.44e-06	192	50	5	d21f0f577156f17c899b08871046a26b88aea011
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SULF1 MXRA8 ADAMTS5 ADGRG4 SVEP1	2.63e-06	195	50	5	f54bc4454270ff06e85596f98199372b50d0179f
ToppCell	Biopsy_Control_(H.)-Mesenchymal-Fibroblasts\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	SULF1 MXRA8 ADAMTS5 ADGRG4 SVEP1	2.97e-06	200	50	5	8d75ce89393df452defacf2ec9a5bd4b7708afbb
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-Tnaive/CM_CD4_activated\|Lung / Manually curated celltypes from each tissue	ZNF793 TRIM2 INO80 RIC3	2.49e-05	151	50	4	9bfb807e1180b31fa9a2c500ce993de9707c070f
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TRIM2 SYDE2 PARP8 NKTR	3.28e-05	162	50	4	80317c4253bf8e897782e562f29835f181c65b98
ToppCell	facs-Heart-RV-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MXRA8 FGF10 ADAMTS5 SVEP1	3.69e-05	167	50	4	3e3d8f6df2feefafad5b44ba0ebf5b5a0fe4ed58
ToppCell	facs-Heart-RV-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MXRA8 FGF10 ADAMTS5 SVEP1	3.69e-05	167	50	4	3ad9f3122dbe96580f640388ef920ea209fc2349
ToppCell	facs-Lung-EPCAM-18m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF35 PRMT9 WDR25 USPL1	3.96e-05	170	50	4	12203d4410f38cc933d9f160b5fb76828df94119
ToppCell	facs-Lung-EPCAM-18m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF35 PRMT9 WDR25 USPL1	3.96e-05	170	50	4	f9decb3bf3bf6d4996b0ac27af768236e116aac5
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MXRA8 FGF10 ADAMTS5 SVEP1	4.14e-05	172	50	4	e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF1 SYDE2 MXRA8 OCLN	4.73e-05	178	50	4	6d9ecfaeb50d562899380de379ebf7b99fd8adc9
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF1 SYDE2 MXRA8 OCLN	4.73e-05	178	50	4	d3f518cd75b02e85d45cbb9b2eff30f0272512a8
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SULF1 MXRA8 ADAMTS5 SVEP1	5.05e-05	181	50	4	c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SULF1 MXRA8 ADAMTS5 SVEP1	5.05e-05	181	50	4	c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MXRA8 FGF10 ADAMTS5 SVEP1	5.27e-05	183	50	4	5cfcd589a480e67654d3d94e71916f122150db10
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MXRA8 FGF10 ADAMTS5 SVEP1	5.27e-05	183	50	4	c3ea8d3b916ffcaca3156e0d77a952724554c4ab
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MXRA8 FGF10 ADAMTS5 SVEP1	5.27e-05	183	50	4	81003ddc24164959dd41bb12fcac72638789b8f2
ToppCell	droplet-Kidney-nan-21m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF1 MXRA8 ADAMTS5 SVEP1	5.38e-05	184	50	4	3bffadb0cb2e0d825bdb6cfc5d23f5436cbc3efd
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	DOCK11 FGF10 MED13L SVEP1	5.38e-05	184	50	4	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D122\|Adult / Lineage, Cell type, age group and donor	SULF1 MXRA8 ADAMTS5 SVEP1	5.38e-05	184	50	4	2b7e6f91e11c228f0521e099886867d9e998e78d
ToppCell	droplet-Kidney-nan-21m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF1 MXRA8 ADAMTS5 SVEP1	5.50e-05	185	50	4	9954fc85b183c1cc45c3c24e3dadc7984ee6f649
ToppCell	droplet-Kidney-nan-21m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF1 MXRA8 ADAMTS5 SVEP1	5.50e-05	185	50	4	33cc0e9d8b54cb7408b51235f2a70e044ebae04d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SULF1 FGF10 ADGRG4 SVEP1	5.85e-05	188	50	4	ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MXRA8 ADAMTS5 ADGRG4 SVEP1	5.97e-05	189	50	4	d531399749409d614adca13d181830c6e3287508
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SULF1 FGF10 ADGRG4 SVEP1	6.10e-05	190	50	4	efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCell	LV-08._Macrophage\|World / Chamber and Cluster_Paper	AP2A2 DOCK11 PARP8 ALCAM	6.22e-05	191	50	4	e7a0bc46ba9ba772636a583f3387748418e18832
ToppCell	LV-02._Fibroblast_II\|World / Chamber and Cluster_Paper	SULF1 MXRA8 ADAMTS5 SVEP1	6.22e-05	191	50	4	d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SULF1 FGF10 ADGRG4 SVEP1	6.22e-05	191	50	4	2c51850f5c559d665b8a27a12b75af9ed58dffe1
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MXRA8 FGF10 ADAMTS5 SVEP1	6.22e-05	191	50	4	cd497abed9e00e4e0becd9dbc036c6e7a60ae791
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	NKTR ALCAM USPL1 ADAM10	6.22e-05	191	50	4	9454f642c3621370fa23640b631301346b300950
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF1 NKTR ADAMTS5 DAAM1	6.22e-05	191	50	4	7d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF1 MXRA8 ADAMTS5 SVEP1	6.35e-05	192	50	4	ac1477433704573f95111eee6263b93668d2845e
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF1 MXRA8 ADAMTS5 SVEP1	6.35e-05	192	50	4	671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SULF1 MXRA8 ADAMTS5 SVEP1	6.35e-05	192	50	4	321850b0f881420c2d57d3e825e365c82fa511ab
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SULF1 MXRA8 ADAMTS5 SVEP1	6.35e-05	192	50	4	7a2e79490e4f7058bb76b46c45b5df9f729e3146
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF1 MXRA8 ADAMTS5 SVEP1	6.35e-05	192	50	4	840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF1 MXRA8 ADAMTS5 SVEP1	6.35e-05	192	50	4	8937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SULF1 MXRA8 ADAMTS5 SVEP1	6.35e-05	192	50	4	cf2765d8bc074f7f9ee864eae632a3b705175842
ToppCell	facs-Trachea-24m-Mesenchymal\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SULF1 MXRA8 ADAMTS5 SVEP1	6.35e-05	192	50	4	e8af6ad1ae99cae13a82d0d8d7f38af9b777f0ba
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SULF1 MXRA8 ADAMTS5 SVEP1	6.35e-05	192	50	4	fc940f91ff8e051631dbf25e6e8d73cf8337eccb
ToppCell	LV-08._Macrophage\|LV / Chamber and Cluster_Paper	AP2A2 DOCK11 PARP8 ALCAM	6.35e-05	192	50	4	7be12d580aaf2f2f1562203fcad3a44639b8c5a6
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF1 MXRA8 ADAMTS5 SVEP1	6.35e-05	192	50	4	e4a7f2673f801b008ca67291db2fb2b9fd2955b8
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF1 MXRA8 ADAMTS5 SVEP1	6.35e-05	192	50	4	136af0186c70c14c5f2b33ed7a148156de5b478c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SULF1 MXRA8 FGF10 SVEP1	6.48e-05	193	50	4	dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MXRA8 FGF10 ADAMTS5 SVEP1	6.48e-05	193	50	4	9d0b966d13cbce97beb43de6dc77f006c363a181
ToppCell	RV-08._Macrophage\|RV / Chamber and Cluster_Paper	AP2A2 DOCK11 PARP8 ALCAM	6.48e-05	193	50	4	12bf98a280f87e4d8f0c6887dfc855da72e47ac1
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SULF1 MXRA8 ADAMTS5 SVEP1	6.48e-05	193	50	4	25248b8e65d558b1a96a87c93e3e5b4c0ba168fe
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SULF1 MXRA8 ADAMTS5 SVEP1	6.48e-05	193	50	4	f1f1097204e07a7bed416425b8256942038a734f
ToppCell	facs-Lung-nan-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF1 MXRA8 ADAMTS5 SVEP1	6.48e-05	193	50	4	d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DOCK11 SULF1 ALCAM SVEP1	6.48e-05	193	50	4	adc9fc94f9ec686a417d08c0b8b7b7ab687afec0
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SULF1 MXRA8 FGF10 SVEP1	6.48e-05	193	50	4	e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCell	COVID-19-Heart-Fib_2\|Heart / Disease (COVID-19 only), tissue and cell type	SULF1 MXRA8 ADAMTS5 SVEP1	6.61e-05	194	50	4	d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell	COVID-19-Heart-Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	AP2A2 DOCK11 PARP8 ALCAM	6.61e-05	194	50	4	f09675cd472200363c458952f00d2e41990800ee
ToppCell	facs-Kidney-nan-18m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF1 MXRA8 ADAMTS5 SVEP1	6.61e-05	194	50	4	bbc625b4cc53bb7d6254fde287258e51f9171572
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SULF1 FGF10 DAAM1 SVEP1	6.61e-05	194	50	4	90efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SULF1 FGF10 DAAM1 SVEP1	6.61e-05	194	50	4	df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCell	facs-Kidney-nan-18m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF1 MXRA8 ADAMTS5 SVEP1	6.61e-05	194	50	4	fcd5e9238d299c41f0bf9693b56cd8c900d2112b
ToppCell	facs-Kidney-nan-18m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SULF1 MXRA8 ADAMTS5 SVEP1	6.61e-05	194	50	4	6afc21c5fec30ab8e373e3e46ab7866204c805b6
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	SULF1 FGF10 ADAMTS5 SVEP1	6.61e-05	194	50	4	5f5f0cdeacd5e1b28717d78dabdb9eb95f661e36
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SULF1 FGF10 DAAM1 SVEP1	6.74e-05	195	50	4	803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCell	IPF-Stromal-Fibroblast\|World / Disease state, Lineage and Cell class	SULF1 MXRA8 ADAMTS5 SVEP1	6.74e-05	195	50	4	9c32756edb54f0c211185d9a98073fe01fd1526a
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SULF1 FGF10 DAAM1 SVEP1	6.74e-05	195	50	4	4f70157d42a16ff0259bc24a62803c4df4285c44
ToppCell	15-Trachea-Mesenchymal\|Trachea / Age, Tissue, Lineage and Cell class	SULF1 MXRA8 ADAMTS5 SVEP1	6.88e-05	196	50	4	7e178c76285e61c721c38d7a995ebf89dc428f9f
ToppCell	Control-Stromal-Fibroblast\|Control / Disease state, Lineage and Cell class	SULF1 MXRA8 ADAMTS5 SVEP1	6.88e-05	196	50	4	7ca94477498a84cafcdd9933ee92a6cbde76c70e
ToppCell	Control-Stromal-Fibroblast\|World / Disease state, Lineage and Cell class	SULF1 MXRA8 ADAMTS5 SVEP1	6.88e-05	196	50	4	1ec7a4daa51b3156db97e1fd6cb925ad311bb4b5
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SULF1 MXRA8 FGF10 SVEP1	6.88e-05	196	50	4	d4676a6b0d9e417795fc9a6bcb1762d3dd656ca9
ToppCell	IPF-Stromal-Fibroblast\|IPF / Disease state, Lineage and Cell class	SULF1 MXRA8 ADAMTS5 SVEP1	6.88e-05	196	50	4	f7ae604ba32b322d86d68b2b54892e7c6ab06c49
ToppCell	15-Trachea-Mesenchymal-Mesenchyme_SERPINF1-high\|Trachea / Age, Tissue, Lineage and Cell class	SULF1 MXRA8 ADAMTS5 SVEP1	6.88e-05	196	50	4	54aefcebf13704f51de84379e2e22ec0734b9461
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SULF1 FGF10 DAAM1 SVEP1	6.88e-05	196	50	4	2b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MXRA8 FGF10 ADAMTS5 SVEP1	7.01e-05	197	50	4	17344464fdcc5ba0c03959696b97c195f11e644c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SULF1 MXRA8 FGF10 SVEP1	7.01e-05	197	50	4	4cf4e9553397cd8dee883dbec24f41bec41aff99
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal-mesenchymal_stem_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MXRA8 FGF10 ADAMTS5 SVEP1	7.01e-05	197	50	4	3bb92dd8a94e2be3b7fe51c9a21b241215477ac7
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SULF1 MXRA8 ADAMTS5 SVEP1	7.01e-05	197	50	4	71786e9432e2d649f5d86f639abb25e7102deb67
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MXRA8 FGF10 ADAMTS5 SVEP1	7.01e-05	197	50	4	5b8d0d7116b20d8e27541e88ec80c9f1f477e384
ToppCell	COPD-Stromal-Fibroblast\|World / Disease state, Lineage and Cell class	SULF1 MXRA8 ADAMTS5 SVEP1	7.15e-05	198	50	4	2f13c0b3372af53d1bd85f9546f315c878580a71
ToppCell	COPD-Stromal-Fibroblast\|COPD / Disease state, Lineage and Cell class	SULF1 MXRA8 ADAMTS5 SVEP1	7.15e-05	198	50	4	7904af61473cb20064f7a3a1e1bfe8d5913cf317
ToppCell	Control-Stromal\|Control / Disease state, Lineage and Cell class	SULF1 MXRA8 ADAMTS5 SVEP1	7.15e-05	198	50	4	ae726b6b7f0a4107899be4d32ac256ffa0bd8d59
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SULF1 MXRA8 ADAMTS5 SVEP1	7.29e-05	199	50	4	1fd7bbb8727607e6507848602a19bc86882ef2d5
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SULF1 MXRA8 ADAMTS5 SVEP1	7.29e-05	199	50	4	993fa050a095017135a6e723c77cd38b9d782e58
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SULF1 MXRA8 ADAMTS5 SVEP1	7.29e-05	199	50	4	9672230aa0bc6a7289050c955f5154ca183a5159
ToppCell	distal-mesenchymal-Adventitial_Fibroblast-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MXRA8 ADAMTS5 ADGRG4 SVEP1	7.29e-05	199	50	4	6e8a44e46b46e87b81dbfc56fcbbcde166fd00fe
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SULF1 MXRA8 ADAMTS5 SVEP1	7.29e-05	199	50	4	e18abe678da293bd01fae55e2f9ab6fdd643d02d
ToppCell	ILEUM-non-inflamed-(8)_Fibroblasts\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	SULF1 MXRA8 ADAMTS5 SVEP1	7.29e-05	199	50	4	d9d7f36b4b5592b7855448730044c90997b55499
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SULF1 MXRA8 ADAMTS5 SVEP1	7.29e-05	199	50	4	f835e7ffe976843b0edbf695762d463da85793f3
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SULF1 MXRA8 FGF10 SVEP1	7.44e-05	200	50	4	b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SETX GATA2 OCLN ADAM10	7.44e-05	200	50	4	b7533c571eeea0cb3678e1a57d3dc036fa8d0f49
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SULF1 MXRA8 ADAMTS5 SVEP1	7.44e-05	200	50	4	28e5354008adf97b17333f17f8cbef930db6729a
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_adventitial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SULF1 MXRA8 ADAMTS5 SVEP1	7.44e-05	200	50	4	b04831708fa20471a127b87e8db3728b6e729ce8
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	SETX GATA2 OCLN ADAM10	7.44e-05	200	50	4	432384faeade8e609154fab3d96c955a8ec868dd
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_adventitial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SULF1 MXRA8 ADAMTS5 SVEP1	7.44e-05	200	50	4	6b48ddde83bc6c941d557844aa214d4d2c8e736d
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SULF1 MXRA8 FGF10 SVEP1	7.44e-05	200	50	4	0c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SULF1 MXRA8 ADAMTS5 SVEP1	7.44e-05	200	50	4	56536236a7012efdb28f85b40e464f3da3e87ce8
ToppCell	distal-mesenchymal-Adventitial_Fibroblast\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SULF1 MXRA8 ADAMTS5 SVEP1	7.44e-05	200	50	4	687cfada2d0977e8985e0a73a5804f84f2ca9c52
ToppCell	droplet-Trachea-nan-3m-Mesenchymal-mesenchymal_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MXRA8 FGF10 ADAMTS5	3.82e-04	126	50	3	c3261ea8726400de87f1c8a5a5134ba2b2884f66
ToppCell	TCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue-2\|TCGA-Bladder / Sample_Type by Project: Shred V9	FGF10 ADGRG4 SVEP1	5.30e-04	141	50	3	1baa054c2ae3b446d1954244b7fbf8af824ef345
Disease	hydrocephalus (is_implicated_in)	L1CAM SMARCC1	4.04e-05	6	49	2	DOID:10908 (is_implicated_in)
Disease	serum albumin measurement	POLR1F TRIM2 IGHG4 RBMS2 SMARCC1 SVEP1	4.27e-04	592	49	6	EFO_0004535
Disease	visual cortical surface area measurement	ALCAM DAAM1	5.04e-04	20	49	2	EFO_0004771
Disease	colorectal cancer (is_marker_for)	L1CAM SMARCC1 ADAM10	2.28e-03	157	49	3	DOID:9256 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
TGKASGNLETKYKVC	VDAC3	51	Q9Y277
PKTKGESANCEKYGK	PRMT9	281	Q6P2P2
CKADETASKYKGTYK	ADGRG4	2386	Q8IZF6
GGICEKSKLYSDGKK	ADAM10	341	O14672
CTKIVGTFNKKSKGY	ADAMTS5	731	Q9UNA0
GDKALDGYSKKKYVC	AP2A1	46	O95782
SSSGGKKCYKLENEK	DAXX	51	Q9UER7
GDKALDGYSKKKYVC	AP2A2	46	O94973
KAILDKTTNKCKGYG	RBMS2	86	Q15434
QVKGSADYKSKKNHC	OCLN	486	Q16625
SKCDKGNLYNFSKLK	INO80	106	Q9ULG1
KNKKANECSSGLKYS	FAM47C	886	Q5HY64
NKVLSKEYCKASGSK	FLG2	86	Q5D862
GCGKSKSKLKSEQDG	PARP8	296	Q8N3A8
SLKKNKSEDGFGTKD	MED13L	741	Q71F56
GKAYLAKGKSDSKHC	NEK5	16	Q6P3R8
SGKGKPLKKFSDCSY	DNAJC28	221	Q9NX36
SKGGKYSVKDKEDTQ	L1CAM	1146	P32004
TGISSKDAGDYKCKA	LRIT3	316	Q3SXY7
KDAGDYKCKAKNLAG	LRIT3	321	Q3SXY7
FKLSKGKTTAEDGKC	RIC3	116	Q7Z5B4
YSDIKGKCKKGAKEF	NSUN6	151	Q8TEA1
YCSKKKDQEENKGAT	DAAM1	86	Q9Y4D1
SNKSKKSKKGAECFE	GATA2	401	P23769
NSYKDEKNSKESKGC	DOCK11	206	Q5JSL3
KKGKLYGSKEFNNDC	FGF10	136	O15520
GKEYKCKVSNKGLPS	IGHG4	196	P01861
NATGDYKCSLIDKKS	ALCAM	306	Q13740
KFGKGKEIISNSCSK	SYDE2	641	Q5VT97
KTTGKKLCYKGSTFH	NKTR	51	P30414
GTKCKYKDCLETTKN	SETX	1546	Q7Z333
KKVYLSECKTGNGKN	PLG	96	P00747
SCNKGFYIKGEKKST	SVEP1	2171	Q4LDE5
YSKKTLAKSKGASAG	SMARCC1	606	Q92922
EENQKCKKSGGKYSL	ZNF35	191	P13682
GKKSNNKEKPYKCST	ZNF624	266	Q9P2J8
YTSQLSGVKDGDCKK	USPL1	281	Q5W0Q7
KTLPKEKSCEYNKFG	ZNF793	106	Q6ZN11
LSSKKSYECQKCGKA	ZNF77	206	Q15935
GQITKGKDGKSKYST	PRRC2B	6	Q5JSZ5
GSDSSGYQSDHKKKK	POLR1F	296	Q3B726
DCSGGKTKKLEVSKN	TRGV11	76	A0A075B6L2
KQKKCYKGSQGDEGS	WDR62	661	O43379
KLYKSEECGKGFTDS	ZNF230	306	Q9UIE0
ASGETAKEGKTYRCK	ZNF362	216	Q5T0B9
CGKGFKYSSTLTKHK	ZNF66	346	Q6ZN08
TVGKNGSSFQKKKCE	WDR25	156	Q64LD2
KDKDGELCKTGNAYL	TRIM2	351	Q9C040
SCSKQSYYNKEKGVK	SULF1	676	Q8IWU6
RDTGKKSFKCIEYGK	ZNF506	166	Q5JVG8
EYSDQKSGKSKGKDV	MXRA8	371	Q9BRK3