Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionnicotinic acid receptor activity

HCAR3 HCAR2

3.53e-062382GO:0070553
GeneOntologyMolecularFunctionprotein sequestering activity

TMC8 CASTOR1 NFKB1

3.65e-0534383GO:0140311
GeneOntologyMolecularFunctionmolecular sequestering activity

TMC8 CASTOR1 NFKB1

1.92e-0459383GO:0140313
GeneOntologyMolecularFunctionnucleotide receptor activity

HCAR3 HCAR2

7.95e-0422382GO:0016502
GeneOntologyMolecularFunctionpurinergic nucleotide receptor activity

HCAR3 HCAR2

7.95e-0422382GO:0001614
GeneOntologyMolecularFunctionactinin binding

LDB3 NFKB1

3.03e-0343382GO:0042805
GeneOntologyBiologicalProcesspositive regulation of adiponectin secretion

HCAR3 HCAR2

1.87e-054372GO:0070165
GeneOntologyBiologicalProcessadiponectin secretion

HCAR3 HCAR2

8.71e-058372GO:0070162
GeneOntologyBiologicalProcessregulation of adiponectin secretion

HCAR3 HCAR2

8.71e-058372GO:0070163
DomainHCAR2/3_rcpt

HCAR3 HCAR2

3.82e-062372IPR028017
DomainEGF

CUBN NRG3 CELSR3

1.97e-03126373PF00008
Pubmed

Activated niacin receptor HCA2 inhibits chemoattractant-mediated macrophage migration via Gβγ/PKC/ERK1/2 pathway and heterologous receptor desensitization.

HCAR3 HCAR2

1.29e-06240228186140
Pubmed

The Immunometabolomic Interface Receptor Hydroxycarboxylic Acid Receptor 2 Mediates the Therapeutic Effects of Dimethyl Fumarate in Autoantibody-Induced Skin Inflammation.

HCAR3 HCAR2

1.29e-06240230154797
Pubmed

The niacin/butyrate receptor GPR109A suppresses mammary tumorigenesis by inhibiting cell survival.

HCAR3 HCAR2

1.29e-06240224371223
Pubmed

High dietary niacin may increase prostaglandin formation but does not increase tumor formation in ApcMin/+ mice.

HCAR3 HCAR2

1.29e-06240221774590
Pubmed

The role of HCA2 (GPR109A) in regulating macrophage function.

HCAR3 HCAR2

1.29e-06240223882124
Pubmed

Crosstalk between microbiome, regulatory T cells and HCA2 orchestrates the inflammatory response in a murine psoriasis model.

HCAR3 HCAR2

1.29e-06240236891315
Pubmed

GPR109a Regulates Phenotypic and Functional Alterations in Macrophages and the Progression of Type 1 Diabetes.

HCAR3 HCAR2

1.29e-06240236208084
Pubmed

Parabacteroides distasonis ameliorates insulin resistance via activation of intestinal GPR109a.

HCAR3 HCAR2

1.29e-06240238007572
Pubmed

The role of the C-terminus of the human hydroxycarboxylic acid receptors 2 and 3 in G protein activation using Gα-engineered yeast cells.

HCAR3 HCAR2

1.29e-06240226656756
Pubmed

Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation.

HCAR3 HCAR2

1.29e-06240237597514
Pubmed

The Role of GPR109a Signaling in Niacin Induced Effects on Fed and Fasted Hepatic Metabolism.

HCAR3 HCAR2

1.29e-06240233924461
Pubmed

Hydroxycarboxylic acid receptor 2 mediates dimethyl fumarate's protective effect in EAE.

HCAR3 HCAR2

1.29e-06240224691444
Pubmed

Ketone Body 3-Hydroxybutyrate Ameliorates Atherosclerosis via Receptor Gpr109a-Mediated Calcium Influx.

HCAR3 HCAR2

1.29e-06240233977048
Pubmed

Butyrate ameliorates caerulein-induced acute pancreatitis and associated intestinal injury by tissue-specific mechanisms.

HCAR3 HCAR2

1.29e-06240231347703
Pubmed

PUMA-G, an IFN-gamma-inducible gene in macrophages is a novel member of the seven transmembrane spanning receptor superfamily.

HCAR3 HCAR2

1.29e-06240211745392
Pubmed

Loss of GPR109A/HCAR2 induces aging-associated hepatic steatosis.

HCAR3 HCAR2

1.29e-06240230659164
Pubmed

Niacin-induced hyperglycemia is partially mediated via niacin receptor GPR109a in pancreatic islets.

HCAR3 HCAR2

1.29e-06240225622782
Pubmed

GPR109A mediates the effects of hippuric acid on regulating osteoclastogenesis and bone resorption in mice.

HCAR3 HCAR2

1.29e-06240233420329
Pubmed

Expression and localization of GPR109A (PUMA-G/HM74A) mRNA and protein in mammalian retinal pigment epithelium.

HCAR3 HCAR2

1.29e-06240219223991
Pubmed

Molecular identification of nicotinic acid receptor.

HCAR3 HCAR2

1.29e-06240212646212
Pubmed

PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect.

HCAR3 HCAR2

1.29e-06240212563315
Pubmed

Niacin increases adiponectin and decreases adipose tissue inflammation in high fat diet-fed mice.

HCAR3 HCAR2

1.29e-06240223967184
Pubmed

Involvement of the Niacin Receptor GPR109a in the LocalControl of Glucose Uptake in Small Intestine of Type 2Diabetic Mice.

HCAR3 HCAR2

1.29e-06240226371038
Pubmed

Alloreactive T cells deficient of the short-chain fatty acid receptor GPR109A induce less graft-versus-host disease.

HCAR3 HCAR2

1.29e-06240234653248
Pubmed

Phenolic acids suppress adipocyte lipolysis via activation of the nicotinic acid receptor GPR109A (HM74a/PUMA-G).

HCAR3 HCAR2

1.29e-06240219136666
Pubmed

G Protein-Coupled Receptor 109A Maintains the Intestinal Integrity and Protects Against ETEC Mucosal Infection by Promoting IgA Secretion.

HCAR3 HCAR2

1.29e-06240233488584
Pubmed

Lactate-induced activation of HCA2 improves survival in mice with sepsis.

HCAR3 HCAR2

1.29e-06240230951370
Pubmed

Niacin Ameliorates Hepatic Steatosis by Inhibiting De Novo Lipogenesis Via a GPR109A-Mediated PKC-ERK1/2-AMPK Signaling Pathway in C57BL/6 Mice Fed a High-Fat Diet.

HCAR3 HCAR2

1.29e-06240231858105
Pubmed

Deficiency of metabolite sensing receptor HCA2 impairs the salutary effect of niacin in hemorrhagic shock.

HCAR3 HCAR2

1.29e-06240230625381
Pubmed

Exploring the role of the metabolite-sensing receptor GPR109a in diabetic nephropathy.

HCAR3 HCAR2

1.29e-06240232068460
Pubmed

The activation of retinal HCA2 receptors by systemic beta-hydroxybutyrate inhibits diabetic retinal damage through reduction of endoplasmic reticulum stress and the NLRP3 inflammasome.

HCAR3 HCAR2

1.29e-06240230657794
Pubmed

Ketones and pain: unexplored role of hydroxyl carboxylic acid receptor type 2 in the pathophysiology of neuropathic pain.

HCAR3 HCAR2

1.29e-06240230085883
Pubmed

Nicotinic acid receptor abnormalities in human skin cancer: implications for a role in epidermal differentiation.

HCAR3 HCAR2

1.29e-06240221655214
Pubmed

Melatonin alleviates titanium nanoparticles induced osteolysis via activation of butyrate/GPR109A signaling pathway.

HCAR3 HCAR2

1.29e-06240234092246
Pubmed

(D)-beta-Hydroxybutyrate inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G.

HCAR3 HCAR2

1.29e-06240215929991
Pubmed

Activation of HCA2 regulates microglial responses to alleviate neurodegeneration in LPS-induced in vivo and in vitro models.

HCAR3 HCAR2

1.29e-06240236991440
Pubmed

Inflammation stimulates niacin receptor (GPR109A/HCA2) expression in adipose tissue and macrophages.

HCAR3 HCAR2

1.29e-06240225320346
Pubmed

Molecular identification of high and low affinity receptors for nicotinic acid.

HCAR3 HCAR2

1.29e-06240212522134
Pubmed

Nicotinic acid inhibits glucose-stimulated insulin secretion via the G protein-coupled receptor PUMA-G in murine islet β cells.

HCAR3 HCAR2

1.29e-06240221441844
Pubmed

G Protein-Coupled Receptor 109A and Host Microbiota Modulate Intestinal Epithelial Integrity During Sepsis.

HCAR3 HCAR2

1.29e-06240230271409
Pubmed

Niacin fine-tunes energy homeostasis through canonical GPR109A signaling.

HCAR3 HCAR2

1.29e-06240230596513
Pubmed

The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer's disease.

HCAR3 HCAR2

1.29e-06240235320002
Pubmed

GPR109A (PUMA-G/HM74A) mediates nicotinic acid-induced flushing.

HCAR3 HCAR2

1.29e-06240216322797
Pubmed

BHBA treatment improves cognitive function by targeting pleiotropic mechanisms in transgenic mouse model of Alzheimer's disease.

HCAR3 HCAR2

1.29e-06240231914599
Pubmed

Nicotinic acid receptor agonists.

HCAR3 HCAR2

1.29e-06240218983141
Pubmed

Gut microbial metabolite butyrate protects against proteinuric kidney disease through epigenetic- and GPR109a-mediated mechanisms.

HCAR3 HCAR2

1.29e-06240231366236
Pubmed

Modulation of HDL metabolism by the niacin receptor GPR109A in mouse hepatocytes.

HCAR3 HCAR2

1.29e-06240220655299
Pubmed

Evidence for constitutive dimerization of niacin receptor subtypes.

HCAR3 HCAR2

1.29e-06240220380810
Pubmed

GPR109A Expression in the Murine Min6 Pancreatic Beta Cell Line, and Its Relation with Glucose Metabolism and Inflammation.

HCAR3 HCAR2

1.29e-06240226116596
Pubmed

Expression and activation of the ketone body receptor HCAR2/GPR109A promotes preservation of retinal endothelial cell barrier function.

HCAR3 HCAR2

1.29e-06240235649469
Pubmed

GPR109A expressed on medullary thymic epithelial cells affects thymic Treg development.

HCAR3 HCAR2

1.29e-06240237595951
Pubmed

The hypophagic response to heat stress is not mediated by GPR109A or peripheral β-OH butyrate.

HCAR3 HCAR2

1.29e-06240226936786
Pubmed

Hydroxycarboxylic Acid Receptor 2, a Pleiotropically Linked Receptor for the Multiple Sclerosis Drug, Monomethyl Fumarate. Possible Implications for the Inflammatory Response.

HCAR3 HCAR2

1.29e-06240234084164
Pubmed

GPR109A gene deletion ameliorates gonadectomy-induced bone loss in mice.

HCAR3 HCAR2

1.29e-06240235489706
Pubmed

Deorphanization of GPR109B as a receptor for the beta-oxidation intermediate 3-OH-octanoic acid and its role in the regulation of lipolysis.

HCAR3 HCAR2

1.29e-06240219561068
Pubmed

Hyperhomocysteinemia is detrimental to pregnancy in mice and is associated with preterm birth.

HCAR3 HCAR2

3.87e-06340223579073
Pubmed

Short-chain fatty acids directly exert anti-inflammatory responses in podocytes and tubular epithelial cells exposed to high glucose.

HCAR3 HCAR2

3.87e-06340237215085
Pubmed

Colonic gene expression in conventional and germ-free mice with a focus on the butyrate receptor GPR109A and the butyrate transporter SLC5A8.

HCAR3 HCAR2

3.87e-06340220033346
Pubmed

Niacin stimulates adiponectin secretion through the GPR109A receptor.

HCAR3 HCAR2

3.87e-06340219141678
Pubmed

International Union of Basic and Clinical Pharmacology. LXXXII: Nomenclature and Classification of Hydroxy-carboxylic Acid Receptors (GPR81, GPR109A, and GPR109B).

HCAR3 HCAR2

3.87e-06340221454438
Pubmed

Nicotinic acid- and monomethyl fumarate-induced flushing involves GPR109A expressed by keratinocytes and COX-2-dependent prostanoid formation in mice.

HCAR3 HCAR2

3.87e-06340220664170
Pubmed

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation.

HCAR3 HCAR2

3.87e-06340224226773
Pubmed

Activation of microglial GPR109A alleviates thermal hyperalgesia in female lupus mice by suppressing IL-18 and glutamatergic synaptic activity.

HCAR3 HCAR2

3.87e-06340234919284
Pubmed

Induction of the cystine/glutamate exchanger SLC7A11 in retinal pigment epithelial cells by the antipsoriatic drug monomethylfumarate.

HCAR3 HCAR2

3.87e-06340223404113
Pubmed

Niacin receptor GPR109A inhibits insulin secretion and is down-regulated in type 2 diabetic islet beta-cells.

HCAR3 HCAR2

3.87e-06340227570060
Pubmed

The β-hydroxybutyrate receptor HCA2 activates a neuroprotective subset of macrophages.

HCAR3 HCAR2

3.87e-06340224845831
Pubmed

Oral Dimethyl Fumarate Targets HCA2-Expressing Skin Cells in the Imiquimod Mouse Model.

HCAR3 HCAR2

3.87e-06340235189149
Pubmed

The Butyrate-Producing Bacterium Clostridium butyricum Suppresses Clostridioides difficile Infection via Neutrophil- and Antimicrobial Cytokine-Dependent but GPR43/109a-Independent Mechanisms.

HCAR3 HCAR2

3.87e-06340233597149
Pubmed

Nicotinic acid-induced flushing is mediated by activation of epidermal langerhans cells.

HCAR3 HCAR2

3.87e-06340217008386
Pubmed

Effects of high fat diet on GPR109A and GPR81 gene expression.

HCAR3 HCAR2

3.87e-06340222842580
Pubmed

Niacin lipid efficacy is independent of both the niacin receptor GPR109A and free fatty acid suppression.

HCAR3 HCAR2

3.87e-06340222914621
Pubmed

Niacin protects against abdominal aortic aneurysm formation via GPR109A independent mechanisms: role of NAD+/nicotinamide.

HCAR3 HCAR2

3.87e-06340231710686
Pubmed

Deficiency of Prebiotic Fiber and Insufficient Signaling Through Gut Metabolite-Sensing Receptors Leads to Cardiovascular Disease.

HCAR3 HCAR2

3.87e-06340232093510
Pubmed

Rare and potentially pathogenic variants in hydroxycarboxylic acid receptor genes identified in breast cancer cases.

HCAR3 HCAR2

3.87e-06340234852802
Pubmed

Dietary Fiber Protects against Diabetic Nephropathy through Short-Chain Fatty Acid-Mediated Activation of G Protein-Coupled Receptors GPR43 and GPR109A.

HCAR3 HCAR2

3.87e-06340232358041
Pubmed

Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells.

HCAR3 HCAR2

3.87e-06340221317532
Pubmed

Dietary Fiber and Bacterial SCFA Enhance Oral Tolerance and Protect against Food Allergy through Diverse Cellular Pathways.

HCAR3 HCAR2

7.73e-06440227332875
Pubmed

Gpr109a Limits Microbiota-Induced IL-23 Production To Constrain ILC3-Mediated Colonic Inflammation.

HCAR3 HCAR2

7.73e-06440229514953
Pubmed

Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis.

HCAR3 HCAR2

7.73e-06440224412617
Pubmed

The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.

HCAR3 HCAR2

7.73e-06440225686106
Pubmed

Clostridium butyricum upregulates GPR109A/AMPK/PGC-1α and ameliorates acute pancreatitis-associated intestinal barrier injury in mice.

HCAR3 HCAR2

7.73e-06440238761195
Pubmed

Niacin activates the PI3K/Akt cascade via PKC- and EGFR-transactivation-dependent pathways through hydroxyl-carboxylic acid receptor 2.

HCAR3 HCAR2

7.73e-06440225375133
Pubmed

Peroxisome proliferator-activated receptor gamma regulates expression of the anti-lipolytic G-protein-coupled receptor 81 (GPR81/Gpr81).

HCAR3 HCAR2

7.73e-06440219633298
Pubmed

Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome.

HCAR3 HCAR2

1.29e-05540225828455
Pubmed

GPR109A as an anti-inflammatory receptor in retinal pigment epithelial cells and its relevance to diabetic retinopathy.

HCAR3 HCAR2

1.29e-05540222427566
Pubmed

Lactate inhibits lipolysis in fat cells through activation of an orphan G-protein-coupled receptor, GPR81.

HCAR3 HCAR2

1.29e-05540219047060
Pubmed

β-Hydroxybutyrate suppresses colorectal cancer.

HCAR3 HCAR2

1.29e-05540235477756
Pubmed

Two complex genotypes relevant to the kynurenine pathway and melanotropin function show association with schizophrenia and bipolar disorder.

HCAR3 HCAR2

1.93e-05640219502010
Pubmed

Chlamydia pneumoniae Hijacks a Host Autoregulatory IL-1β Loop to Drive Foam Cell Formation and Accelerate Atherosclerosis.

HCAR3 HCAR2

1.93e-05640229937375
Pubmed

Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity.

HCAR3 HCAR2

2.70e-05740232901017
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KIAA1549 SMPD4 MAST4 CELSR3 USP6NL KIF21A

2.98e-0552940614621295
Pubmed

Vagal neuron expression of the microbiota-derived metabolite receptor, free fatty acid receptor (FFAR3), is necessary for normal feeding behavior.

HCAR3 HCAR2

3.60e-05840234626852
Pubmed

Negative regulation of constitutive NF-kappaB and JNK signaling by PKN1-mediated phosphorylation of TRAF1.

PKN1 NFKB1

3.60e-05840218429822
Pubmed

Microbiota modulate sympathetic neurons via a gut-brain circuit.

HCAR3 HCAR2

1.34e-041540232641826
Pubmed

DNA sequence and analysis of human chromosome 18.

TMEM200C MEX3C

1.73e-041740216177791
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ANKRD11 PKN1 AADAT NRG3 ZNF827 AHDC1 TSPAN9 DNAH1

2.50e-04148940828611215
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

KIAA1549 PUM2 CELSR3

4.56e-0413040312421765
Pubmed

Splicing Regulator p54nrb /Non-POU Domain-Containing Octamer-Binding Protein Enhances Carcinogenesis Through Oncogenic Isoform Switch of MYC Box-Dependent Interacting Protein 1 in Hepatocellular Carcinoma.

SMPD4 KIF21A

6.26e-043240231815296
Pubmed

Dilated Cardiomyopathy Overview

LDB3 RBM20

6.26e-043240220301486
Pubmed

Genome-wide contribution of genotype by environment interaction to variation of diabetes-related traits.

NRG3 NFKB1

6.66e-043340224204828
GeneFamilyHydroxy-carboxylic acid receptors

HCAR3 HCAR2

5.06e-063242200
CoexpressionGSE3203_WT_VS_IFNAR1_KO_INFLUENZA_INFECTED_LN_BCELL_DN

TMC8 EVPL LDB3 CASTOR1 TSPAN9

1.15e-05200395M6798
ToppCellfacs-Lung-EPCAM-18m-Epithelial-Basal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT7 HCAR2 ZNF827 PTPRZ1 KIF21A

7.24e-07189405783c1db856f2defe6f3b8748dd0bc29a8102f6d1
ToppCellfacs-Lung-EPCAM-18m-Epithelial-respiratory_basal_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT7 HCAR2 ZNF827 PTPRZ1 KIF21A

7.24e-0718940588b72fafbe58463543e0818f27f3dd9e5b4d34d2
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KRT7 HCAR2 ZNF827 PTPRZ1 KIF21A

7.44e-0719040547e07ea22733306d8885ee9e5f0b033e2f5e2afb
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KRT7 HCAR2 ZNF827 PTPRZ1 KIF21A

7.44e-07190405261b8afddfdcba4f70b50df126cef7ad00a0aae0
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

LDB3 MAST4 RBM20 TSPAN9 KIF21A

7.63e-071914055d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_C-8|TCGA-Thymus / Sample_Type by Project: Shred V9

HCAR3 CATSPERB FGD5 NRG3

1.12e-0515540400eef9f93a753a1fe1ab5fd8dae026e7be556cde
ToppCell5'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EECs|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EVPL CATSPERB AADAT BRSK1

1.65e-05171404dd37e1693a5cfc42e40992d504f92048a8038b52
ToppCell10x5'v1-week_17-19-Myeloid_neutrophil-granulo-eo/baso/mast-eosinophil|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

HCAR3 EVPL HCAR2 MAST4

1.98e-05179404d16dc58b5b22762a5a3c875563ced18022d08908
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

KIAA1549 MAST4 CUBN KIF21A

2.21e-0518440451ed1ebfdef45149541917c66cbacad87072e51f
ToppCell18-Airway-Epithelial-Club-like_secretory|Airway / Age, Tissue, Lineage and Cell class

HCAR3 KRT7 HCAR2 PTPRZ1

2.35e-05187404d1e301afcc39054ae1f867d80e564e30a137e3f8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIAA1549 MAST4 CUBN KIF21A

2.45e-0518940413fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIAA1549 MAST4 CUBN KIF21A

2.45e-05189404204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIAA1549 CUBN NRG3 KIF21A

2.50e-05190404989d4eefd22d66ecb857836f8fdbcf41e3047f84
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-leukocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT7 HCAR2 PTPRZ1 KIF21A

2.55e-05191404116fba9badea093e11f370996247cca0e4c02e8f
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

LDB3 MAST4 RBM20 KIF21A

2.60e-05192404ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCellfacs-Lung-EPCAM-18m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT7 HCAR2 PTPRZ1 KIF21A

2.60e-0519240412096302a3a4d26e21ca04357aa557143f482155
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

ANKRD11 MAST4 CUBN TSPAN9

2.60e-05192404e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HCAR3 HCAR2 PTPRZ1 KIF21A

2.66e-05193404739fb2a57772a800a2e94bdd6c71285bb2c162a7
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

LDB3 MAST4 RBM20 KIF21A

2.66e-05193404dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCellRA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

LDB3 MAST4 RBM20 KIF21A

2.71e-0519440489812fb164065041357bb37a3c2d87028ec3de4e
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

LDB3 MAST4 RBM20 KIF21A

2.71e-05194404c3535f7cc0076653c72db582047cff053c322397
ToppCell3'_v3-blood-Lymphocytic_NK-NK_CD56bright_CD16-|blood / Manually curated celltypes from each tissue

ANKRD11 ZNF827 AHDC1 NFKB1

2.77e-051954041470f562ebcfe7da367964ecfd6c7f43bcdb4a73
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KRT7 HCAR2 PTPRZ1 KIF21A

2.77e-05195404ed052c6d3dc104b02e34b645abfdee477af050c6
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

LDB3 MAST4 RBM20 KIF21A

2.77e-0519540475fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellPCW_10-12-Epithelial|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

EVPL CATSPERB PTPRZ1 KIF21A

2.82e-051964049bfb31ff3e4f2c0a9405c418c86bfec5dbca23e2
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar-Dividing_AT2|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

EVPL KRT7 LDB3 CELSR3

2.88e-0519740449689a03ab31e53386dbe15c77c09ca3a14ebf4e
ToppCellproximal-Epithelial-Differentiating_Basal-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KRT7 HCAR2 PTPRZ1 KIF21A

3.00e-05199404c607346f60e5997e757e5a31cab412ab3734377b
ToppCellproximal-3-Epithelial-Differentiating_Basal|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KRT7 HCAR2 PTPRZ1 KIF21A

3.00e-0519940412e07084fc2d5d4c418df564ccc0e132b056e549
ToppCellproximal-Epithelial-Differentiating_Basal|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KRT7 HCAR2 PTPRZ1 KIF21A

3.00e-0519940496a89a2578fad9a99c52d2cf9e26e06516a96568
ToppCellControl-Epithelial_alveolar-Mes-Like|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PROSER1 PTPRZ1 RBM20

1.54e-04116403df7609503782d8d7e4f31ed2a626916e5474d5bc
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_1|E16.5-samps / Age Group, Lineage, Cell class and subclass

PROSER1 DNAJB5 CASTOR1

1.54e-04116403f32f7eddfe33adb3b5cf7c34667a481a305c5163
ToppCellControl-Epithelial_alveolar-Mes-Like-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PROSER1 PTPRZ1 RBM20

2.01e-04127403556aaf88719c83f307fa50dfac151136ed05c8ad
ToppCellASK452-Epithelial-Secretory|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

HCAR3 MAST4 PTPRZ1

2.25e-0413240349ba24e24b3127b5257a88a0ee0246c9843c580a
ToppCell343B-Lymphocytic-NK_cells-NK_cell_A2|343B / Donor, Lineage, Cell class and subclass (all cells)

CASTOR1 MEX3C DNAH1

2.30e-041334038ff1cf0ea1fc33fe8384c0e65c1ee1853b25a2ae
ToppCell10x5'-blood-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM|blood / Manually curated celltypes from each tissue

TMEM78 RBM20 MEX3C

2.46e-04136403f024015bf60e64b8657e410e24995a1edec85196
ToppCellASK454-Epithelial-Type_2|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

SMPD4 AADAT USP6NL

2.46e-04136403ff9a5e111993fdb3ac64c5ef269e3460ff994517
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TMC8 CUBN CELSR3

3.28e-0415040353de595376a9fc92491dfd58ff25938b0bf79903
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TMC8 CUBN CELSR3

3.28e-04150403e4b40b3243ed26d0c46bf196ac06e148834e7ed2
ToppCellE15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TMC8 FGD5 BRSK1

3.54e-04154403e65e4636646164610f33f7bbac0d879a3ea55986
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|390C / Donor, Lineage, Cell class and subclass (all cells)

HCAR3 BRSK1 INTS1

3.61e-0415540315bacd06cc2b02b13c85bb71c5b758e5ff613e80
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

LDB3 BRSK1 RBM20

4.03e-0416140364891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LDB3 DNAJB5 RBM20

4.18e-0416340351dee6c21cbeca4e17d1cc386e203f0c403089e8
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Basal_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

HCAR3 NRG3 PTPRZ1

4.18e-04163403f21951e63188eb0c04675a8f81a0da495c26c007
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

LDB3 BRSK1 RBM20

4.18e-041634038f24cef152f5965727bbeee116bd26c75cbba82a
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_C|TCGA-Thymus / Sample_Type by Project: Shred V9

CATSPERB FGD5 NRG3

4.18e-041634032dac87d15051151ccf193760ddd8b82534c3f922
ToppCellBAL-Severe-cDC_8|Severe / Compartment, Disease Groups and Clusters

HCAR3 HCAR2 BRSK1

4.25e-04164403e8cbe7e01eca32886eb44e02d5333056b6bebc50
ToppCellClub-club-16|World / Class top

ANKRD11 KRT7 KIF21A

4.33e-04165403684f3c4872bd630d3f744f15d57dccfd34e96160
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KRT7 HCAR2 PTPRZ1

4.49e-04167403d1a13d6ada572d8ddb2da95e6e122d2b705fad7f
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231|Adult / Lineage, Cell type, age group and donor

FGD5 NRG3 CELSR3

4.49e-041674035af9127bae05768a5164d5708a4ad37edca99324
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CUBN KIF21A DNAH1

4.56e-041684039a8709d34865cfa668d8f3335dc34fc86fc32482
ToppCellAdult-Endothelial-endothelial_cell_of_vein-D175|Adult / Lineage, Cell type, age group and donor

FGD5 NRG3 TSPAN9

4.64e-04169403e1f0298236e4a1c59077c14f0dd29a78fac12648
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT7 CUBN DNAH1

4.64e-0416940312bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CATSPERB FGD5 NRG3

4.72e-04170403dcc64b73134e89ae37990d4878813b86ce91dae9
ToppCell15-Airway-Epithelial-Club-like_secretory|Airway / Age, Tissue, Lineage and Cell class

EVPL KRT7 HCAR2

4.72e-041704031418031cc4b4a87a48621eb53a3c819cd713ddd0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CATSPERB FGD5 NRG3

4.72e-041704036035c92cd39c5ac54e7ec57d94888ee19f574639
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CATSPERB FGD5 NRG3

4.72e-04170403c8c42eda44b61440c96b202e7f54650046eb95d3
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_ACHE|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FGD5 PTPRZ1 TMEM200C

4.72e-0417040336dbbdb13f69307afd2122ff051b2980850c1f00
ToppCellControl-Myeloid-Mast|World / Disease state, Lineage and Cell class

KIAA1549 MAST4 NFKB1

4.81e-04171403ed8e61d524f4cddc6084b261175df54d2a64a60f
ToppCellAdult-Endothelial-endothelial_cell_of_vein-D231|Adult / Lineage, Cell type, age group and donor

FGD5 NRG3 TSPAN9

5.06e-041744032dd647c4fdf99fd1f7b838efef01baf2cbc3446d
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_3|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

EVPL KRT7 PTPRZ1

5.06e-041744039e5fae9ecc7c0111fc8a252e72b89dc89c0d3a7c
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma|TCGA-Cervix / Sample_Type by Project: Shred V9

HCAR3 HCAR2 PTPRZ1

5.23e-041764038513c2a05a34453a16bbcf1c11cb34c580133e47
ToppCellAdult-Endothelial-endothelial_cell_of_vein|Adult / Lineage, Cell type, age group and donor

FGD5 NRG3 TSPAN9

5.23e-04176403043683c61c5d1a7f8a4666a612310246bd3d83a2
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-respiratory_basal_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KRT7 HCAR2 PTPRZ1

5.40e-04178403fb8f8d95f6b08378fb42c4076ee040276faa296f
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neuron_precursor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CELSR3 PTPRZ1 KIF21A

5.40e-04178403a9ba4089413b1c55d667ce836b6972ca572ee2b8
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CELSR3 PTPRZ1 KIF21A

5.40e-0417840313dfd28a80889c2dacdc65b94a41bb9762dc409d
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KRT7 HCAR2 PTPRZ1

5.40e-04178403b89c4d015b44bf538aa39969ef8778877c8023f1
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA1549 TMEM200C DNAH1

5.49e-04179403b44e2d53b82c3c141bfc6539054b19708200a0d9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CUBN NRG3 KIF21A

5.49e-0417940358ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCelldroplet-Fat-Bat-18m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LDB3 USP6NL TSPAN9

5.49e-041794039863ab3ceb160a4b1d9790033a4ac48845863d65
ToppCelldroplet-Fat-Bat-18m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LDB3 USP6NL TSPAN9

5.49e-04179403dfe110add7228cd834b35916cbcc849769a01bb9
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KIAA1549 MAST4 CUBN

5.49e-04179403d1ef7e1cb00336118e387b47f4f8120f53584391
ToppCelldroplet-Fat-Bat-18m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LDB3 USP6NL TSPAN9

5.49e-04179403e6224864eb76a2e9c1fc0c61513d9e936bb5c72c
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CELSR3 BRSK1 PTPRZ1

5.58e-04180403c72f15763ba707189e29c85db533557f01c7fdb1
ToppCell343B-Lymphocytic-NK_cells-NK_cell_A2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CASTOR1 MEX3C DNAH1

5.58e-0418040362511d76d24b836839c3dcc2bf30485ffe9401e2
ToppCellLV|World / Chamber and Cluster_Paper

LDB3 MAST4 RBM20

5.58e-041804035ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCell368C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PROSER1 CUBN CASTOR1

5.58e-04180403eb5a57604c7f2ad256c300085dbf5069d0ae1ad0
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMC8 HCAR3 HCAR2

5.58e-041804031c5515f29ead129bee3b4ca27799796956811a39
ToppCell368C-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PROSER1 CUBN CASTOR1

5.58e-04180403ddba4dc3bbcfe4e4a22400be73bbc62d3ff27d3c
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

FGD5 NRG3 TSPAN9

5.67e-04181403c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

CUBN NRG3 RBM20

5.67e-04181403c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCellBAL-Control-Epithelial-Epithelial-Basal/Club|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EVPL KRT7 PTPRZ1

5.67e-04181403faff2a34e391d053a17c926540e6cb46d94dd629
ToppCellPND07-Epithelial-Epithelial_Airway-Basal-Basal|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EVPL KRT7 KIF21A

5.67e-041814036b43dcaeeb02ad5900772b6f16f1581847050e38
ToppCellBAL-Control-Epithelial-Epithelial-Basal/Club|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

EVPL KRT7 PTPRZ1

5.67e-0418140358651853f9c715075889856793df66ebe00c04f1
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KIAA1549 MAST4 CUBN

5.67e-041814039542c19edc9bd2cba68c01c2a8407705398e3011
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KIAA1549 MAST4 CUBN

5.67e-041814038f04f8cac5d705dc5f6cf6f4516d6e45b0aa4ae5
ToppCellPND07-Epithelial-Epithelial_Airway-Basal|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EVPL KRT7 KIF21A

5.67e-04181403f50561fdacfb83ba85fe6476e7cbc2bad1ebc826
ToppCellBAL-Control-Epithelial-Epithelial-Basal/Club-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EVPL KRT7 PTPRZ1

5.67e-041814035a9c332c0bf07cc20eaf8cf77b45e73668a6467d
ToppCellBAL-Control-Epithelial-Epithelial-Basal/Club-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

EVPL KRT7 PTPRZ1

5.67e-04181403488a517f6e5543b648a2e72e0e04332fad776de6
ToppCellCOPD-Myeloid-Mast|World / Disease state, Lineage and Cell class

KIAA1549 MAST4 NFKB1

5.76e-0418240368a1e7b804f309bfd6c23d65fad20a9a962712ae
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

LDB3 MAST4 RBM20

5.76e-04182403287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Basal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT7 HCAR2 PTPRZ1

5.85e-04183403ecac1cfaff7553a60305b34d6cede6973ffb5430
ToppCellCOVID-19-Heart-CM_4|COVID-19 / Disease (COVID-19 only), tissue and cell type

LDB3 RBM20 KIF21A

5.85e-041834032902b6e8aa9a6f62bc1a792c971ab7f651a8e676
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CATSPERB FGD5 NRG3

5.85e-04183403bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCellfacs-Lung-EPCAM-3m-Epithelial-respiratory_basal_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT7 HCAR2 PTPRZ1

5.85e-04183403f6ebfd7f61e912f92bd07313cc213a171747ac03
ToppCellCOVID-19-kidney-PCT-S1/S2|kidney / Disease (COVID-19 only), tissue and cell type

KIAA1549 MAST4 CUBN

5.95e-04184403dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

LDB3 MAST4 RBM20

5.95e-04184403ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Proximal_secretory_progenitors|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

EVPL KRT7 HCAR2

5.95e-04184403fcb5dd4fb3fa79f3b6029fad32a474cacde35a3b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIAA1549 MAST4 CUBN

5.95e-041844039434731f651820b05335085582960f08fbf895de
ToppCellCOVID-19-Endothelial_cells-Arterial_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

FGD5 MAST4 TSPAN9

5.95e-041844030f19494789f38ab1a420545e15e748ca7eb345c3
ToppCellwk_15-18-Epithelial-Proximal_epithelial-basal_proximal|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

HCAR3 HCAR2 PTPRZ1

5.95e-04184403575de705053da8b289670b5c40c1627c0833b5ed
Drughistrionicotoxin

PUM2 HCAR3 HCAR2

7.00e-0622393CID005282247
DrugNiacin

HCAR3 HCAR2

1.71e-054392DB00627
Diseaseinternal carotid intimal medial thickness

MAST4 NRG3

1.70e-055392EFO_0005053
DiseaseOral ulcer

HCAR3 HCAR2 NFKB1

3.85e-04107393HP_0000155
DiseasePrimary familial dilated cardiomyopathy

LDB3 RBM20

7.23e-0430392cv:C0340427
DiseasePrimary dilated cardiomyopathy

LDB3 RBM20

9.30e-0434392cv:C0007193
Diseasetriglyceride measurement, phospholipid measurement

HCAR3 HCAR2 DNAH1

9.52e-04146393EFO_0004530, EFO_0004639
DiseaseParoxysmal atrial fibrillation

LINC00477 RBM20 MEX3C

1.15e-03156393C0235480
DiseasePersistent atrial fibrillation

LINC00477 RBM20 MEX3C

1.15e-03156393C2585653
Diseasefamilial atrial fibrillation

LINC00477 RBM20 MEX3C

1.15e-03156393C3468561
Diseasehepatocyte growth factor-like protein measurement

CELSR3 DNAH1

1.16e-0338392EFO_0008154
DiseaseAtrial Fibrillation

LINC00477 RBM20 MEX3C

1.24e-03160393C0004238
DiseaseSecondary Biliary Cholangitis

KRT7 NFKB1

1.42e-0342392C0238065
DiseaseBiliary Cirrhosis, Primary, 1

KRT7 NFKB1

1.42e-0342392C4551595
DiseaseBiliary cirrhosis

KRT7 NFKB1

1.42e-0342392C0023892
Diseasedilated cardiomyopathy (is_implicated_in)

LDB3 RBM20

1.49e-0343392DOID:12930 (is_implicated_in)
DiseaseFamilial dilated cardiomyopathy

LDB3 RBM20

1.55e-0344392C0340427
DiseasePrimary biliary cirrhosis

KRT7 NFKB1

1.77e-0347392C0008312
DiseaseCardiomyopathy

LDB3 RBM20

1.77e-0347392cv:C0878544
DiseaseMetastatic melanoma

PKN1 BRSK1

2.33e-0354392C0278883
Diseaselow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

HCAR3 HCAR2 DNAH1

2.34e-03200393EFO_0004611, EFO_0020945
Diseasetriglycerides:total lipids ratio, high density lipoprotein cholesterol measurement

HCAR3 HCAR2 DNAH1

2.55e-03206393EFO_0004612, EFO_0020947
DiseaseSkin Neoplasms

HCAR3 HCAR2

2.78e-0359392C0037286
DiseaseMalignant neoplasm of skin

HCAR3 HCAR2

2.78e-0359392C0007114
DiseaseHDL cholesterol change measurement, physical activity

HCAR3 HCAR2

3.06e-0362392EFO_0003940, EFO_0007805

Protein segments in the cluster

PeptideGeneStartEntry
SAFSVPVRPFFSLGS

BTN2A3P

446

Q96KV6
SSAPSPYLRASFSSA

AADAT

391

Q8N5Z0
FFASSRSTRPFSGFD

DNAJB5

111

O75953
APTSACSPSFFDRFS

ANKRD11

1751

Q6UB99
QSKFPIFRFPSSFSS

CATSPERB

396

Q9H7T0
ASSSPEPSSITFFAF

CASTOR1

216

Q8WTX7
SFFSSPSLANSIRSP

AHDC1

166

Q5TGY3
ARSFTQSSPTFPLAS

RBM20

491

Q5T481
SLFSSSSQLFPPSRL

PUM2

681

Q8TB72
PRGALDFASSFFSTP

KIAA1549

616

Q9HCM3
TTAPFFSSSTLGSRP

NRG3

196

P56975
TFSPAFSRPSAFSSL

LDB3

141

O75112
TAFFSATADAASPFP

INTS1

1561

Q8N201
SSPVFTSRSAAFSGR

KRT7

6

P08729
FSSPSFPNFFSTLIN

HCAR2

296

Q8TDS4
PQSTSFFSPSFSLGL

EVPL

1806

Q92817
PLSSPRFSGSAFSSV

FGD5

1321

Q6ZNL6
GAPLLPFSSASFSSE

PTPRZ1

816

P23471
RLFTAPTFTGSFLSP

SMPD4

541

Q9NXE4
FASTSAPFTSLPFST

PROSER1

396

Q86XN7
APFTSLPFSTSSSAA

PROSER1

401

Q86XN7
TSSFDTVSSPRFPAN

CUBN

1626

O60494
ALSNLPTFSSFSSDF

DNAH1

3576

Q9P2D7
FRKIRSSAPSSPSFS

GDF5-AS1

176

Q5U4N7
SSSPLSSPRSPVFSF

BRSK1

441

Q8TDC3
SPRNFSPSASAHFSF

MAST4

261

O15021
SFLPASFFSSSCLPV

KRTAP26-1

96

Q6PEX3
FDSSAPFLASASTLF

CELSR3

1396

Q9NYQ7
SKFSDFPFPTRRASS

SPATA6L

246

Q8N4H0
SPSSSSTSVGFFFRI

TMEM200C

141

A6NKL6
FSSPSFPNFFSTLIN

HCAR3

296

P49019
SNRLADFSPTSPFST

MEX3C

461

Q5U5Q3
SSAAFSTRLAGPFPA

PKN1

296

Q16512
SSFQGSPATPLSFLF

LINC00477

16

Q96M19
KPSSSDTFFRFSPSS

UHRF1BP1L

786

A0JNW5
FPTANSSFASPQFSP

USP6NL

646

Q92738
SSRPFRASSSTFFFQ

TMC8

521

Q8IU68
TARAPYFSGSSTFSP

KIF21A

511

Q7Z4S6
RFESFSSPFSSQSAS

ZNF827

236

Q17R98
PFFSEDTFRQSPFTS

ZNF827

761

Q17R98
PFFPSFFLSLSLSPS

TMEM78

81

Q5T7P6
FATFSPSFPSLSAAN

TSPAN9

41

O75954
FTAFLPDSTGSFTRR

NFKB1

216

P19838