Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium channel activity

PKD1L1 PKD1L3 RYR1 RYR3 ITPR3 ORAI1 CNGA3

5.69e-051291517GO:0005262
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

RYR1 RYR3 ITPR3 CNGA3

1.08e-04331514GO:0005217
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

PKD1L1 PKD1L3 RYR1 RYR3 ITPR3 ORAI1 CNGA3

1.53e-041511517GO:0015085
GeneOntologyMolecularFunctionmonoatomic cation channel activity

PKD1L1 ABCC9 PKD1L3 CHRNA4 RYR1 RYR3 ITPR3 ORAI1 CNGA3 UNC80

2.89e-0434315110GO:0005261
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

RYR1 RYR3 ITPR3

3.18e-04181513GO:0015278
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR1 RYR3

3.37e-0441512GO:0005219
GeneOntologyMolecularFunctioncytoskeletal protein binding

HAUS6 BIN1 NRAP MYO1A EML4 KIF1B ENC1 CAPZB NEB NF1 PTPRN CEP135 CEP70 KIF28P MACF1 MTCL1 DMD GNB3 CNGA3

6.44e-04109915119GO:0008092
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

ABCC9 CHRNA4 RYR1 RYR3 ITPR3 CNGA3 GABRR3

6.76e-041931517GO:0015276
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

ABCC9 CHRNA4 RYR1 RYR3 ITPR3 CNGA3

6.91e-041401516GO:0099094
GeneOntologyMolecularFunctionmonoatomic ion channel activity

PKD1L1 ABCC9 PKD1L3 CHRNA4 RYR1 RYR3 ITPR3 ORAI1 CNGA3 UNC80 GABRR3

7.54e-0445915111GO:0005216
GeneOntologyMolecularFunctionligand-gated channel activity

ABCC9 CHRNA4 RYR1 RYR3 ITPR3 CNGA3 GABRR3

7.63e-041971517GO:0022834
GeneOntologyMolecularFunctionATP-dependent activity

DNHD1 ABCA2 MYO1A ABCA13 KIF1B ABCC9 ORC1 MDN1 FBH1 ATP6V0A4 KIF28P MACF1 DYNC1H1

8.03e-0461415113GO:0140657
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR1 RYR3

8.35e-0461512GO:0048763
GeneOntologyMolecularFunctionretinoic acid binding

UGT2B7 UGT2B15 UGT2B17

1.21e-03281513GO:0001972
GeneOntologyCellularComponentsomatodendritic compartment

ZC3H14 RELN BIN1 MYO1A COPA DLGAP4 KIF1B ENC1 CAPZB NCAM1 RET NR3C1 CHRM2 CHRNA4 ITPR3 NF1 RACK1 SACS PTPRN WASHC5 DMD GNB3 CNGA3 DYNC1H1

1.12e-05122815424GO:0036477
GeneOntologyCellularComponentaxon

ATG5 ZC3H14 TSHZ3 RELN BIN1 MYO1A COPA KIF1B NCAM1 RET CHRM2 ORAI1 NF1 SACS PTPRN DMD CNGA3 DYNC1H1 UNC80

3.15e-0589115419GO:0030424
GeneOntologyCellularComponentcell body

RELN MYO1A COPA DLGAP4 ENC1 CAPZB NCAM1 RET CHRM2 GFAP CHRNA4 ITPR3 RACK1 PTPRN WASHC5 DMD GNB3 CNGA3 DYNC1H1

5.52e-0592915419GO:0044297
GeneOntologyCellularComponenttransmembrane transporter complex

ABCA2 PKD1L1 ABCC9 PKD1L3 CHRNA4 RYR1 RYR3 ORAI1 SLC9A1 ATP6V0A4 CNGA3 UNC80 GABRR3

1.37e-0452315413GO:1902495
GeneOntologyCellularComponentneuronal cell body

RELN MYO1A COPA DLGAP4 ENC1 CAPZB NCAM1 RET CHRM2 CHRNA4 ITPR3 RACK1 PTPRN WASHC5 DMD CNGA3 DYNC1H1

1.47e-0483515417GO:0043025
GeneOntologyCellularComponentWASH complex

WASHC4 CAPZB WASHC5

1.67e-04151543GO:0071203
GeneOntologyCellularComponentnuclear outer membrane

ITPR3 UGT2B7 UGT2B15 UGT2B17

2.11e-04401544GO:0005640
GeneOntologyCellularComponenttransporter complex

ABCA2 PKD1L1 ABCC9 PKD1L3 CHRNA4 RYR1 RYR3 ORAI1 SLC9A1 ATP6V0A4 CNGA3 UNC80 GABRR3

2.24e-0455015413GO:1990351
GeneOntologyCellularComponentorganelle outer membrane

BCL2L2 MLXIP CPT1A ITPR3 UGT2B7 UGT2B15 UGT2B17 DMD IMMT

2.32e-042791549GO:0031968
GeneOntologyCellularComponentcytoplasmic vesicle membrane

ATG5 MRC1 IL15RA BIN1 ABCA2 WASHC4 COPA DSP ABCA13 PLEKHF2 KIF1B RET CHRM2 ITPR3 PTPRN WASHC5 CADPS ATP6V0A4 RAB15 ADGRE5 DMD ULK2

2.39e-04130715422GO:0030659
GeneOntologyCellularComponentouter membrane

BCL2L2 MLXIP CPT1A ITPR3 UGT2B7 UGT2B15 UGT2B17 DMD IMMT

2.44e-042811549GO:0019867
GeneOntologyCellularComponentvesicle membrane

ATG5 MRC1 IL15RA BIN1 ABCA2 WASHC4 COPA DSP ABCA13 PLEKHF2 KIF1B RET CHRM2 ITPR3 PTPRN WASHC5 CADPS ATP6V0A4 RAB15 ADGRE5 DMD ULK2

2.89e-04132515422GO:0012506
GeneOntologyCellularComponentcation channel complex

PKD1L1 ABCC9 PKD1L3 RYR1 RYR3 ORAI1 CNGA3 UNC80

3.62e-042351548GO:0034703
GeneOntologyCellularComponentmonoatomic ion channel complex

PKD1L1 ABCC9 PKD1L3 CHRNA4 RYR1 RYR3 ORAI1 CNGA3 UNC80 GABRR3

5.08e-0437815410GO:0034702
GeneOntologyCellularComponentsarcomere

BIN1 NRAP CAPZB ABCC9 NEB RYR1 RYR3 DMD

5.31e-042491548GO:0030017
GeneOntologyCellularComponentcholinergic synapse

DLGAP4 CHRM2 CHRNA4

5.45e-04221543GO:0098981
GeneOntologyCellularComponentdendrite

ZC3H14 RELN BIN1 DLGAP4 KIF1B CAPZB RET NR3C1 CHRM2 CHRNA4 ITPR3 NF1 RACK1 SACS GNB3 CNGA3

6.09e-0485815416GO:0030425
GeneOntologyCellularComponentdendritic tree

ZC3H14 RELN BIN1 DLGAP4 KIF1B CAPZB RET NR3C1 CHRM2 CHRNA4 ITPR3 NF1 RACK1 SACS GNB3 CNGA3

6.24e-0486015416GO:0097447
GeneOntologyCellularComponentATPase dependent transmembrane transport complex

ABCA2 ABCC9 SLC9A1 ATP6V0A4

7.21e-04551544GO:0098533
GeneOntologyCellularComponentZ disc

BIN1 NRAP NEB RYR1 RYR3 DMD

8.98e-041511546GO:0030018
GeneOntologyCellularComponentmyofibril

BIN1 NRAP CAPZB ABCC9 NEB RYR1 RYR3 DMD

9.65e-042731548GO:0030016
GeneOntologyCellularComponentsupramolecular fiber

HAUS6 BIN1 NRAP MYO1A DSP EML4 KIF1B CAPZB ABCC9 NEB GFAP RYR1 RYR3 KRT23 KIF28P MACF1 MTCL1 DMD DYNC1H1

1.10e-03117915419GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

HAUS6 BIN1 NRAP MYO1A DSP EML4 KIF1B CAPZB ABCC9 NEB GFAP RYR1 RYR3 KRT23 KIF28P MACF1 MTCL1 DMD DYNC1H1

1.19e-03118715419GO:0099081
GeneOntologyCellularComponentcontractile muscle fiber

BIN1 NRAP CAPZB ABCC9 NEB RYR1 RYR3 DMD

1.42e-032901548GO:0043292
GeneOntologyCellularComponentI band

BIN1 NRAP NEB RYR1 RYR3 DMD

1.46e-031661546GO:0031674
GeneOntologyCellularComponentpreribosome

RIOK3 MDN1 PWP2 PDCD11 RIOK2

1.57e-031141545GO:0030684
GeneOntologyCellularComponentcytoplasmic side of membrane

DIABLO GFAP RYR1 RYR3 ITPR3 GNB3 EFCAB7

1.61e-032301547GO:0098562
GeneOntologyCellularComponentjunctional membrane complex

RYR1 RYR3

1.88e-0391542GO:0030314
GeneOntologyCellularComponentcalcium channel complex

PKD1L1 RYR1 RYR3 ORAI1

2.08e-03731544GO:0034704
GeneOntologyCellularComponentNLS-dependent protein nuclear import complex

MYBBP1A SNUPN

2.33e-03101542GO:0042564
GeneOntologyCellularComponentT-tubule

BIN1 ABCC9 RYR1 SLC9A1

2.77e-03791544GO:0030315
GeneOntologyCellularComponentsarcolemma

BIN1 ABCC9 RYR1 RYR3 SLC9A1 DMD

2.88e-031901546GO:0042383
GeneOntologyCellularComponentnucleocytoplasmic transport complex

MYBBP1A SNUPN

3.39e-03121542GO:0031074
HumanPhenoPes cavus

TRAPPC11 BIN1 SPEG KIF1B CARS1 NARS1 RET NEB RYR1 ITPR3 NF1 SACS WASHC5 MAFB DYNC1H1

1.12e-063045915HP:0001761
HumanPhenoAbnormal calf musculature morphology

TRAPPC11 BIN1 NEB RYR1 SACS WASHC5 DMD

1.45e-0571597HP:0001430
HumanPhenoGowers sign

TRAPPC11 BIN1 SPEG RYR1 RYR3 ORAI1 DMD

2.71e-0578597HP:0003391
MousePhenoneonatal lethality, complete penetrance

ATG5 TSHZ3 BIN1 KIF1B RET NR3C1 CHRNA4 RYR1 ORAI1 CADPS CEP135 PRDM12 MAFB MAPK6 DYNC1H1 UNC80

1.77e-0553412316MP:0011087
MousePhenoabnormal Sertoli cell barrier morphology

BCL2L2 ORAI1 NF1

2.27e-0571233MP:0020355
DomainRIH_assoc-dom

RYR1 RYR3 ITPR3

9.98e-0661503IPR013662
DomainIns145_P3_rec

RYR1 RYR3 ITPR3

9.98e-0661503PF08709
DomainRIH_assoc

RYR1 RYR3 ITPR3

9.98e-0661503PF08454
DomainRIH_dom

RYR1 RYR3 ITPR3

9.98e-0661503IPR000699
DomainIns145_P3_rcpt

RYR1 RYR3 ITPR3

9.98e-0661503IPR014821
DomainRyanodine_recept-rel

RYR1 RYR3 ITPR3

9.98e-0661503IPR015925
Domain-

RYR1 RYR3 ITPR3

9.98e-06615031.25.10.30
DomainRYDR_ITPR

RYR1 RYR3 ITPR3

9.98e-0661503PF01365
DomainMIR

RYR1 RYR3 ITPR3

5.85e-05101503PF02815
DomainMIR_motif

RYR1 RYR3 ITPR3

5.85e-05101503IPR016093
DomainMIR

RYR1 RYR3 ITPR3

5.85e-05101503PS50919
DomainMIR

RYR1 RYR3 ITPR3

5.85e-05101503SM00472
DomainTeashirt_fam

TSHZ3 TSHZ2

1.91e-0431502IPR027008
DomainRyanodine_rcpt

RYR1 RYR3

1.91e-0431502IPR003032
DomainRIO_kinase_CS

RIOK3 RIOK2

1.91e-0431502IPR018935
DomainRyanrecept_TM4-6

RYR1 RYR3

1.91e-0431502IPR009460
DomainRyR

RYR1 RYR3

1.91e-0431502PF02026
DomaintRNA_intron_Endonuc_cat-like

TSEN2 TSEN15

1.91e-0431502IPR006677
DomainRIO

RIOK3 RIOK2

1.91e-0431502SM00090
DomainRR_TM4-6

RYR1 RYR3

1.91e-0431502PF06459
DomainRIO1

RIOK3 RIOK2

1.91e-0431502PS01245
DomainRyan_recept

RYR1 RYR3

1.91e-0431502IPR013333
DomainLH2

PKD1L1 PKD1L3 LOXHD1

3.79e-04181503SM00308
DomainNebulin

NRAP NEB

3.80e-0441502PF00880
DomainNEBULIN

NRAP NEB

3.80e-0441502PS51216
DomainNEBU

NRAP NEB

3.80e-0441502SM00227
DomainNebulin

NRAP NEB

3.80e-0441502IPR013998
DomainRIO_kinase

RIOK3 RIOK2

3.80e-0441502IPR000687
DomainNebulin_repeat

NRAP NEB

3.80e-0441502IPR000900
Domain-

PKD1L1 PKD1L3 LOXHD1

6.07e-042115032.60.60.20
DomainUDPGT

UGT2B7 UGT2B15 UGT2B17

6.07e-04211503PF00201
DomainPLAT

PKD1L1 PKD1L3 LOXHD1

6.07e-04211503PF01477
DomainPLAT/LH2_dom

PKD1L1 PKD1L3 LOXHD1

6.07e-04211503IPR001024
DomainPLAT

PKD1L1 PKD1L3 LOXHD1

6.07e-04211503PS50095
DomainUDPGT

UGT2B7 UGT2B15 UGT2B17

6.07e-04211503PS00375
DomainUDP_glucos_trans

UGT2B7 UGT2B15 UGT2B17

6.07e-04211503IPR002213
Domain-

DSP MACF1

9.41e-04615023.90.1290.10
DomainAAA

ABCA2 ABCA13 ABCC9 ORC1 MDN1 DYNC1H1

1.09e-031441506SM00382
DomainAAA+_ATPase

ABCA2 ABCA13 ABCC9 ORC1 MDN1 DYNC1H1

1.09e-031441506IPR003593
DomainPlectin

DSP MACF1

1.31e-0371502PF00681
DomainPlectin_repeat

DSP MACF1

1.31e-0371502IPR001101
DomainPLEC

DSP MACF1

1.31e-0371502SM00250
DomainKinase-like_dom

SPEG RIOK3 RET MELK TNNI3K IKBKE BTK MACF1 DMD MAPK6 RIOK2 ULK2

1.45e-0354215012IPR011009
DomainSpectrin_repeat

DSP MACF1 DMD

1.59e-03291503IPR002017
DomainHATC_C_dom

ZBED6 ZMYM1

1.74e-0381502IPR008906
DomainDimer_Tnp_hAT

ZBED6 ZMYM1

1.74e-0381502PF05699
DomainWD40_repeat_CS

COPA EML4 NWD2 RACK1 PWP2 GNB3

2.11e-031641506IPR019775
DomainSPEC

DSP MACF1 DMD

2.12e-03321503SM00150
DomainSpectrin/alpha-actinin

DSP MACF1 DMD

2.12e-03321503IPR018159
DomainGPS

PKD1L1 PKD1L3 ADGRE5

2.99e-03361503PS50221
DomainGPS

PKD1L1 PKD1L3 ADGRE5

3.23e-03371503IPR000203
DomainRap_GAP_dom

RALGAPB RALGAPA2

3.36e-03111502IPR000331
DomainRAPGAP

RALGAPB RALGAPA2

3.36e-03111502PS50085
DomainPKD_channel

PKD1L1 PKD1L3

3.36e-03111502PF08016
DomainPKD1_2_channel

PKD1L1 PKD1L3

3.36e-03111502IPR013122
DomainABC_A

ABCA2 ABCA13

4.01e-03121502IPR026082
DomainG-protein_beta_WD-40_rep

COPA RACK1 PWP2 GNB3

4.89e-03851504IPR020472
Domain-

RYR1 RYR3 RASGRP3 USP32 MACF1 DMD EFCAB7

5.20e-0326115071.10.238.10
DomainDynein_HC_stalk

DNHD1 DYNC1H1

5.47e-03141502IPR024743
DomainDynein_heavy_dom-2

DNHD1 DYNC1H1

5.47e-03141502IPR013602
DomainDHC_N2

DNHD1 DYNC1H1

5.47e-03141502PF08393
DomainATPase_dyneun-rel_AAA

MDN1 DYNC1H1

5.47e-03141502IPR011704
DomainMT

DNHD1 DYNC1H1

5.47e-03141502PF12777
DomainAAA_5

MDN1 DYNC1H1

5.47e-03141502PF07728
DomainWD40

COPA EML4 PPP2R2C NWD2 RACK1 PWP2 GNB3

5.99e-032681507SM00320
DomainProt_kinase_dom

SPEG RIOK3 RET MELK TNNI3K IKBKE BTK MAPK6 RIOK2 ULK2

6.20e-0348915010IPR000719
DomainDHC_fam

DNHD1 DYNC1H1

6.28e-03151502IPR026983
DomainDynein_heavy

DNHD1 DYNC1H1

6.28e-03151502PF03028
DomainDynein_heavy_dom

DNHD1 DYNC1H1

6.28e-03151502IPR004273
DomainWD40_repeat

COPA EML4 PPP2R2C NWD2 RACK1 PWP2 GNB3

6.48e-032721507IPR001680
DomainPROTEIN_KINASE_DOM

SPEG RIOK3 RET MELK TNNI3K IKBKE BTK MAPK6 RIOK2 ULK2

6.56e-0349315010PS50011
DomainABC_tran

ABCA2 ABCA13 ABCC9

6.74e-03481503PF00005
DomainABC_TRANSPORTER_2

ABCA2 ABCA13 ABCC9

6.74e-03481503PS50893
DomainABC_TRANSPORTER_1

ABCA2 ABCA13 ABCC9

7.14e-03491503PS00211
DomainPH

DOK6 PLEKHF2 KIF1B ARHGEF18 ARHGEF39 CADPS BTK

7.27e-032781507SM00233
DomainWD_REPEATS_1

COPA EML4 PPP2R2C NWD2 RACK1 PWP2 GNB3

7.27e-032781507PS00678
DomainWD_REPEATS_2

COPA EML4 PPP2R2C NWD2 RACK1 PWP2 GNB3

7.41e-032791507PS50082
DomainWD_REPEATS_REGION

COPA EML4 PPP2R2C NWD2 RACK1 PWP2 GNB3

7.41e-032791507PS50294
DomainPH_DOMAIN

DOK6 PLEKHF2 KIF1B ARHGEF18 ARHGEF39 CADPS BTK

7.41e-032791507PS50003
DomainPH_domain

DOK6 PLEKHF2 KIF1B ARHGEF18 ARHGEF39 CADPS BTK

7.55e-032801507IPR001849
DomainABC_transporter-like

ABCA2 ABCA13 ABCC9

7.55e-03501503IPR003439
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ATG5 RELN BIN1 ABCA2 WASHC4 COPA DSP KIF1B ENC1 NARS1 UBASH3A GFAP RYR3 MIPOL1 PPP2R5E FBH1 SACS SBNO1 CADPS USP32 CEP70 MACF1 IMMT DYNC1H1

2.64e-0912851542435914814
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

MYBBP1A BIN1 COPA DSP DLGAP4 KIF1B CAPZB NARS1 NCAM1 GFAP PPP2R2C NWD2 PPP2R5E NF1 RACK1 SACS WASHC5 CADPS NUFIP2 MACF1 DMD GNB3 IMMT DYNC1H1

2.08e-0814311542437142655
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

ATG5 MYBBP1A WASHC4 COPA DSP EML4 CAPZB NARS1 RIOK3 ACTL6A MELK ORC1 GTF2H1 NF1 MDN1 RACK1 WASHC5 PDCD11 MACF1 CDC27 RIOK2 IMMT DYNC1H1

3.32e-0813531542329467282
Pubmed

Tissue distribution and relative gene expression of UDP-glucuronosyltransferases (2B7, 2B15, 2B17) in the human fetus.

UGT2B7 UGT2B15 UGT2B17

8.51e-083154323223495
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

WASHC4 COPA DSP NEB GFAP ITPR3 RACK1 USP32 MACF1 DMD DYNC1H1

2.24e-073221541126514267
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

ZC3H14 MYBBP1A COPA DSP NARS1 ITPR3 NF1 MDN1 RACK1 NUFIP2 PWP2 PDCD11 MACF1 IMMT DYNC1H1

2.41e-076531541522586326
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SPEG DLGAP4 KIF1B RALGAPB MLXIP PPP2R5E CADPS NUFIP2 MACF1 MTCL1 ULK2 DYNC1H1

3.02e-074071541212693553
Pubmed

Characterization of the binding sites for the interactions between FKBP12 and intracellular calcium release channels.

RYR1 RYR3 ITPR3

3.39e-074154322100703
Pubmed

Impacts of the Glucuronidase Genotypes UGT1A4, UGT2B7, UGT2B15 and UGT2B17 on Tamoxifen Metabolism in Breast Cancer Patients.

UGT2B7 UGT2B15 UGT2B17

3.39e-074154326176234
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

HAUS6 MYBBP1A COPA DSP KIF1B CAPZB NARS1 ANKRD50 RACK1 NUFIP2 C1QBP MACF1 CDC27 IMMT DYNC1H1

6.66e-077081541539231216
Pubmed

Membrane depolarization causes a direct activation of G protein-coupled receptors leading to local Ca2+ release in smooth muscle.

CHRM2 RYR1 RYR3

1.69e-066154319549818
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

RYR1 RYR3 ITPR3

1.69e-066154325966694
Pubmed

A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.

RYR1 RYR3 ITPR3

1.69e-066154320519450
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

RYR1 RYR3 ITPR3

1.69e-066154323463619
Pubmed

IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.

RYR1 RYR3 ITPR3

1.69e-066154316844763
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

HAUS6 MYBBP1A DIABLO EML4 KIF1B CAPZB BBS9 MELK MIPOL1 GTF2H1 PPP2R5E NF1 CNOT6L SBNO1 NUFIP2 C3 TFB2M CDC27 IMMT DYNC1H1

1.71e-0613211542027173435
Pubmed

Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.

RYR1 RYR3 ITPR3

2.94e-067154311860456
Pubmed

Weak activity of UDP-glucuronosyltransferase toward Bisphenol analogs in mouse perinatal development.

UGT2B7 UGT2B15 UGT2B17

2.94e-067154326074487
Pubmed

ATG5 is required for B cell polarization and presentation of particulate antigens.

ATG5 ZC3H14 MYBBP1A COPA EML4 CARS1 NARS1 ACTL6A NR3C1 CPT1A ITPR3 RACK1 NUFIP2 IMMT

3.16e-067011541430196744
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

ZC3H14 MYBBP1A COPA DSP CAPZB NARS1 ACTL6A ITPR3 GTF2H1 RACK1 NUFIP2 PWP2 C1QBP PDCD11 C3 RAB15 TFB2M IMMT DYNC1H1

3.25e-0612571541936526897
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

HAUS6 MYBBP1A WASHC4 COPA ACTL6A TSEN2 ORC1 PPP2R5E CNOT6L RACK1 WASHC5 CEP135 C1QBP ZMYM1 MTCL1 CDC27 TSEN15 DYNC1H1

3.96e-0611551541820360068
Pubmed

Hetero-oligomer formation of mouse UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity towards morphine, an activity which is absent in homo-oligomers of either UGT.

UGT2B7 UGT2B15 UGT2B17

4.69e-068154332093886
Pubmed

Simultaneous evaluation of six human glucuronidation activities in liver microsomes using liquid chromatography-tandem mass spectrometry.

UGT2B7 UGT2B15 UGT2B17

4.69e-068154322579593
Pubmed

ORAI1, STIM1/2, and RYR1 shape subsecond Ca2+ microdomains upon T cell activation.

RYR1 RYR3 ORAI1

4.69e-068154330563862
Pubmed

Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States.

UGT2B7 UGT2B15 UGT2B17

4.69e-068154320142249
Pubmed

Cytoarchitecture of the olfactory bulb in the laggard mutant mouse.

RELN NCAM1 GFAP

4.69e-068154324931760
Pubmed

The configuration of the 17-hydroxy group variably influences the glucuronidation of beta-estradiol and epiestradiol by human UDP-glucuronosyltransferases.

UGT2B7 UGT2B15 UGT2B17

4.69e-068154318719240
Pubmed

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

RYR1 RYR3 ITPR3

4.69e-068154319033399
Pubmed

Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.

TRAPPC11 MYBBP1A WASHC4 RALGAPB CAPZB CARS1 ACTL6A AZI2 NF1 RACK1 PWP2

6.27e-064541541133226137
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

WWC3 RALGAPB ANKRD50 RALGAPA2 NWD2 MACF1

6.86e-06103154610574462
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

ATG5 BIN1 GNPDA1 WASHC4 COPA DIABLO KIF1B CAPZB CARS1 NARS1 NR3C1 TSEN2 PPP2R5E RACK1 SBNO1 WASHC5 C1QBP MACF1 PSMD14 DYNC1H1

7.23e-0614551542022863883
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

DNHD1 MYBBP1A DIABLO DSP NEB MDN1 MACF1 DMD

1.05e-05234154836243803
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

MYBBP1A COPA DSP SNUPN MELK NF1 MDN1 MACF1 MTCL1 GNB3 CDC27 DYNC1H1

1.20e-055821541220467437
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

HAUS6 GNPDA1 TBC1D30 ARHGEF18 BCL2L2 RALGAPA2 SACS RASGRP3 CEP135 MACF1 UNC80

1.35e-054931541115368895
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

ZC3H14 MYBBP1A COPA DSP CAPZB ITPR3 NF1 MDN1 RACK1 SACS PWP2 C1QBP PDCD11 MACF1 IMMT DYNC1H1

1.36e-0510241541624711643
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

BIN1 NRAP DSP KIF1B RIOK3 ANKRD50 NEB RYR1 PPP2R5E RACK1 MACF1

1.46e-054971541123414517
Pubmed

HENA, heterogeneous network-based data set for Alzheimer's disease.

BIN1 CEP135 MACF1 DMD IMMT DYNC1H1

1.65e-05120154631413325
Pubmed

The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex.

WASHC4 CAPZB WASHC5

1.82e-0512154319922875
Pubmed

Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.

UGT2B7 UGT2B15 UGT2B17

1.82e-0512154320308471
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

MYBBP1A COPA DSP EML4 NARS1 ITPR3 RACK1 PDCD11 MACF1 C3 PSMD14 IMMT DYNC1H1

1.83e-057111541333022573
Pubmed

RACK1 Is an Interaction Partner of ATG5 and a Novel Regulator of Autophagy.

ATG5 RACK1

1.95e-052154227325703
Pubmed

Orai1 mediates exacerbated Ca(2+) entry in dystrophic skeletal muscle.

ORAI1 DMD

1.95e-052154223185465
Pubmed

Contractile impairment and structural alterations of skeletal muscles from knockout mice lacking type 1 and type 3 ryanodine receptors.

RYR1 RYR3

1.95e-05215429489997
Pubmed

Identification and validation of the microRNA response elements in the 3'-untranslated region of the UDP glucuronosyltransferase (UGT) 2B7 and 2B15 genes by a functional genomics approach.

UGT2B7 UGT2B15

1.95e-052154228962835
Pubmed

The UDP glucuronosyltransferase gene superfamily: suggested nomenclature based on evolutionary divergence.

UGT2B15 UGT2B17

1.95e-05215421909870
Pubmed

A regulatory subunit of protein phosphatase 2A, PPP2R5E, regulates the abundance of microtubule crosslinking factor 1.

PPP2R5E MTCL1

1.95e-052154227521566
Pubmed

UDP-glucuronosyltransferase 2B15 (UGT2B15) and UGT2B17 enzymes are major determinants of the androgen response in prostate cancer LNCaP cells.

UGT2B15 UGT2B17

1.95e-052154217848572
Pubmed

Androgen and Estrogen Receptors in Breast Cancer Coregulate Human UDP-Glucuronosyltransferases 2B15 and 2B17.

UGT2B15 UGT2B17

1.95e-052154227496708
Pubmed

Expression and functional activity of ryanodine receptors (RyRs) during skeletal muscle development.

RYR1 RYR3

1.95e-052154217118445
Pubmed

The uridine diphosphate glucuronosyltransferase 2B15 D85Y and 2B17 deletion polymorphisms predict the glucuronidation pattern of androgens and fat mass in men.

UGT2B15 UGT2B17

1.95e-052154217698910
Pubmed

Patient affected by neurofibromatosis type 1 and thyroid C-cell hyperplasia harboring pathogenic germ-line mutations in both NF1 and RET genes.

RET NF1

1.95e-052154224361808
Pubmed

Principal mutation hotspot for central core disease and related myopathies in the C-terminal transmembrane region of the RYR1 gene.

RYR1 RYR3

1.95e-052154212565913
Pubmed

Functional and morphological features of skeletal muscle from mutant mice lacking both type 1 and type 3 ryanodine receptors.

RYR1 RYR3

1.95e-05215429192302
Pubmed

Glial cell line-derived neurotrophic factor (GDNF) induces neuritogenesis in the cochlear spiral ganglion via neural cell adhesion molecule (NCAM).

NCAM1 RET

1.95e-052154223262364
Pubmed

Pharmacokinetic and pharmacodynamic interaction of lorazepam and valproic acid in relation to UGT2B7 genetic polymorphism in healthy subjects.

UGT2B7 UGT2B15

1.95e-052154217687269
Pubmed

Isolation and partial cloning of ryanodine-sensitive Ca2+ release channel protein isoforms from human myometrial smooth muscle.

RYR1 RYR3

1.95e-05215427556644
Pubmed

Rare and frequent promoter methylation, respectively, of TSHZ2 and 3 genes that are both downregulated in expression in breast and prostate cancers.

TSHZ3 TSHZ2

1.95e-052154221423795
Pubmed

Mouse UDP glucuronosyltransferase. cDNA and complete amino acid sequence and regulation.

UGT2B15 UGT2B17

1.95e-05215423117546
Pubmed

Genetic mapping of the locus controlling structural variations of murine C3 in the chromosome 17.

ITPR3 C3

1.95e-0521542458159
Pubmed

Lethal multiple pterygium syndrome, large cystic hygroma, and cleft palate: Rare and severe fetal presentations of RYR1- and NEB-related congenital myopathies.

NEB RYR1

1.95e-052154238520674
Pubmed

Expression of UDP Glucuronosyltransferases 2B15 and 2B17 is associated with methylation status in prostate cancer cells.

UGT2B15 UGT2B17

1.95e-052154232660355
Pubmed

Neurofibromin interacts with the cytoplasmic Dynein Heavy Chain 1 in melanosomes of human melanocytes.

NF1 DYNC1H1

1.95e-052154223583712
Pubmed

The block of ryanodine receptors selectively inhibits fetal myoblast differentiation.

RYR1 RYR3

1.95e-052154212640042
Pubmed

Androgen glucuronidation: an unexpected target for androgen deprivation therapy, with prognosis and diagnostic implications.

UGT2B15 UGT2B17

1.95e-052154224121496
Pubmed

Possible involvement of ryanodine receptor-mediated intracellular calcium release in the effect of corticotropin-releasing factor on adrenocorticotropin secretion.

RYR1 RYR3

1.95e-052154214592949
Pubmed

Novel associations of UDP-glucuronosyltransferase 2B gene variants with prostate cancer risk in a multiethnic study.

UGT2B15 UGT2B17

1.95e-052154224267955
Pubmed

Adipocytes contain a novel complex similar to the tuberous sclerosis complex.

RALGAPB RALGAPA2

1.95e-052154216490346
Pubmed

Differential expression of the androgen-conjugating UGT2B15 and UGT2B17 enzymes in prostate tumor cells during cancer progression.

UGT2B15 UGT2B17

1.95e-052154222170718
Pubmed

The glucocorticoid receptor acts locally to protect dystrophic muscle and heart during disease.

NR3C1 DMD

1.95e-052154238770680
Pubmed

Morphological abnormalities of adrenal gland and hypertrophy of liver in mutant mice lacking ryanodine receptors.

RYR1 RYR3

1.95e-05215429799464
Pubmed

Localization of UDP glucuronosyltransferase gene(s) on mouse chromosome 5.

UGT2B15 UGT2B17

1.95e-05215423105095
Pubmed

RyR3 amplifies RyR1-mediated Ca(2+)-induced Ca(2+) release in neonatal mammalian skeletal muscle.

RYR1 RYR3

1.95e-052154211500519
Pubmed

Expression of NCAM and its polysialylated isoforms during mdx mouse muscle regeneration and in vitro myogenesis.

NCAM1 DMD

1.95e-05215427919966
Pubmed

Circulating CD56+ NKG2D+ NK cells and postoperative fertility in ovarian endometrioma.

NCAM1 KLRK1

1.95e-052154233122818
Pubmed

Ryanodine receptors in muscarinic receptor-mediated bronchoconstriction.

RYR1 RYR3

1.95e-052154215894801
Pubmed

AKR1D1 regulates glucocorticoid availability and glucocorticoid receptor activation in human hepatoma cells.

AKR1D1 NR3C1

1.95e-052154230769091
Pubmed

Region-specific astrogliosis in brains of mice heterozygous for mutations in the neurofibromatosis type 1 (Nf1) tumor suppressor.

GFAP NF1

1.95e-05215429878702
Pubmed

Common allosteric mechanisms between ryanodine and inositol-1,4,5-trisphosphate receptors.

RYR1 ITPR3

1.95e-052154221150295
Pubmed

Effect of calmodulin on Ca2+-induced Ca2+ release of skeletal muscle from mutant mice expressing either ryanodine receptor type 1 or type 3.

RYR1 RYR3

1.95e-05215429817784
Pubmed

KIF1B and NF1 are the most frequently mutated genes in paraganglioma and pheochromocytoma tumors.

KIF1B NF1

1.95e-052154228515046
Pubmed

Analysis of DOK-6 function in downstream signaling of RET in human neuroblastoma cells.

DOK6 RET

1.95e-052154220210798
Pubmed

Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36 as the Predominant Isoform Involved in Morphine Glucuronidation.

UGT2B15 UGT2B17

1.95e-052154228228532
Pubmed

Cellular specific expression of the androgen-conjugating enzymes UGT2B15 and UGT2B17 in the human prostate epithelium.

UGT2B15 UGT2B17

1.95e-052154215666817
Pubmed

Phosphorylation of BACH1 switches its function from transcription factor to mitotic chromosome regulator and promotes its interaction with HMMR.

MYBBP1A EML4 ACTL6A MTCL1 DYNC1H1

2.14e-0575154529459360
Pubmed

Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.

GFAP MDN1 SACS MACF1 DYNC1H1

2.29e-0576154527542412
Pubmed

A dual function of Bcl11b/Ctip2 in hippocampal neurogenesis.

RELN DSP GFAP

2.36e-0513154322588081
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

MYBBP1A COPA NELFCD EML4 MDN1 RACK1 PWP2 C1QBP PDCD11 PSMD14 IMMT DYNC1H1

2.95e-056381541233239621
Pubmed

Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

TRAPPC11 TSHZ3 HAUS6 MYBBP1A BIN1 SLF1 NRAP PLEKHF2 TMEM39B TMTC2 ACTL6A CHRM2 RASGRP3

3.18e-057501541311230166
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

MYO1A COPA DSP CAPZB KRT23 MDN1 RACK1 C1QBP C3 PSMD14 IMMT DYNC1H1

3.37e-056471541226618866
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

ZC3H14 TBC1D30 RALGAPB ORC1 ORAI1 SLC9A1 GTF2H1 PPP2R5E MDN1 CNOT6L RACK1 ZBED6 NUFIP2 PWP2 PDCD11 MACF1 TFB2M CDC27 IMMT

3.72e-0514971541931527615
Pubmed

IGF-I promotes neuronal migration and positioning in the olfactory bulb and the exit of neuroblasts from the subventricular zone.

RELN NCAM1 GFAP

3.73e-0515154319712103
Pubmed

Physiological and pathophysiological characteristics of ataxin-3 isoforms.

COPA DIABLO DSP RACK1 NUFIP2 C1QBP PSMD14 DYNC1H1

3.88e-05281154830455355
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

DNHD1 COPA ABCA13 SERPINA2 RYR1 ORC1 RACK1

4.18e-05208154733230847
Pubmed

SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response.

MYBBP1A COPA DSP RACK1 NUFIP2 C1QBP PDCD11 ZMYM1 IMMT DYNC1H1

4.42e-054631541034901782
Pubmed

Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy.

NRAP CAPZB DMD

4.57e-0516154316717059
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

MYBBP1A COPA DSP NWD2 NF1 WASHC5 CADPS NUFIP2 C3 IMMT

5.48e-054751541031040226
Pubmed

Identification of RanBP 9/10 as interacting partners for protein kinase C (PKC) gamma/delta and the D1 dopamine receptor: regulation of PKC-mediated receptor phosphorylation.

GFAP MACF1 DYNC1H1

5.53e-0517154320395553
Pubmed

Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.

RYR1 RYR3

5.83e-053154218403125
Pubmed

Characterization and mapping of the 12 kDa FK506-binding protein (FKBP12)-binding site on different isoforms of the ryanodine receptor and of the inositol 1,4,5-trisphosphate receptor.

RYR1 RYR3

5.83e-053154211171121
Pubmed

Copy-number variations (CNVs) of the human sex steroid metabolizing genes UGT2B17 and UGT2B28 and their associations with a UGT2B15 functional polymorphism.

UGT2B15 UGT2B17

5.83e-053154219572376
Cytoband4q13

UGT2B7 UGT2B15 UGT2B17

1.64e-051515434q13
Cytoband12q24.31

DIABLO MLXIP ORAI1 SBNO1

1.58e-0480154412q24.31
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR1 RYR3

1.04e-0431072287
GeneFamilytRNA-splicing endonuclease subunits

TSEN2 TSEN15

2.07e-0441072776
GeneFamilyWASH complex

WASHC4 WASHC5

5.12e-04610721331
GeneFamilyUDP glucuronosyltransferases

UGT2B7 UGT2B15 UGT2B17

8.82e-04321073363
GeneFamilyEF-hand domain containing|Plakins

DSP MACF1

9.49e-0481072939
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

DOK6 PLEKHF2 KIF1B ARHGEF18 CADPS BTK

1.42e-032061076682
GeneFamilyATP binding cassette subfamily A

ABCA2 ABCA13

3.01e-03141072805
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

TSHZ3 TSHZ2

3.46e-03151072529
GeneFamilyWD repeat domain containing|Protein phosphatase 2 regulatory subunits

PPP2R2C PPP2R5E

3.46e-03151072696
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

BCL2L2 RYR1 ITPR3 SLC9A1 SACS

4.44e-031811075694
GeneFamilyActins|Deafness associated genes

OTOA DIABLO TECTA LOXHD1

4.56e-0311310741152
GeneFamilyWD repeat domain containing

COPA EML4 PPP2R2C RACK1 PWP2 GNB3

4.67e-032621076362
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN KIF1B RET PTPRN CADPS MACF1 GMPR DYNC1H1 UNC80

2.76e-0819515497796ea9247f4c63762f0de8490fed08b9717fa23
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN KIF1B RET PTPRN CADPS MACF1 GMPR DYNC1H1 UNC80

2.76e-0819515493e519cffa6144a62b06124642a14c9ff39b76554
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTOA RELN ABCA13 NEB RYR3 LOXHD1 DMD UNC80

2.63e-0718415482cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTOA RELN ABCA13 NEB RYR3 LOXHD1 DMD UNC80

2.63e-0718415482b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTOA RELN ABCA13 NEB RYR3 LOXHD1 DMD UNC80

2.63e-071841548ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellC_00|World / shred on cell type and cluster

TSHZ2 MLXIP TSEN2 RACK1 CADPS MAFB ADGRE5

3.04e-061791547da2dadc3266ffebd4a34ac61bfa05fddcadcde4c
ToppCellEC-Sinusoidal_ECs|EC / Lineage and Cell class

MRC1 ENC1 ABCC9 RACK1 BAMBI GMPR MAFB

5.00e-0619315471291b1d3494dcb4b9309f8bff63fb662e7eca0c8
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COPA KIF1B NEB PTPRN CADPS GMPR UNC80

5.00e-061931547fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell(4)_Endothelial_cells-(42)_EC-sinusoidal|World / Cell class and subclass of bone marrow stroma cells in homeostatis

MRC1 ENC1 ABCC9 RALGAPA2 RASGRP3 GMPR MAFB

5.17e-0619415474428b472c2042f88eae028b1770767512a515b75
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

WASHC4 DSP ARHGEF18 RACK1 MTCL1 CNGA3

6.41e-061311546a3a086ce6e69707ca6a042f3b15c130f81909acb
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

EML4 CHRNA4 KLRK1 NUFIP2 MACF1 DYNC1H1

1.24e-05147154694998bc40f5c08295cfe3bdcbe43f13b1e564b3d
ToppCellControl-B_naive-1|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SLF1 WASHC4 DSP ARHGEF18 RACK1 MACF1

1.67e-0515515460a78d1cab2bdba2dc8a74cdf35b5a0192370c4b5
ToppCellfacs-Brain_Myeloid-Cerebellum-24m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 ARHGEF18 RYR1 KLRK1 ZBP1 C3

2.00e-0516015461f7acdc8b08152d5817fc53bbf47b4a22d9c91b5
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MRC1 PKD1L3 MAFB GNB3 RIOK2 IMMT

2.55e-051671546881f64db8dea3faa7588bf04d87c20924a4e5952
ToppCellCOVID-19-kidney-Lymphatic_EC|kidney / Disease (COVID-19 only), tissue and cell type

MRC1 RELN RALGAPA2 OR52I2 RASGRP3 GNB3

2.55e-05167154697d0fea1f41c1c00e36d9b5c4c1f0dd85087056f
ToppCellBronchial_Biopsy-Immune-Mast_cells|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

WWC3 XKR6 BBS9 RYR3 MIPOL1 CADPS

2.64e-05168154645ccc0cb42d21f4853190e8e9ed9a54aefefe738
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-basal_bladder_epithelial_cell_(Krt5+Krt14+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HAUS6 EML4 GMPR TFB2M GNB3 EFCAB7

2.64e-051681546ca65321259711321c175ede67bd67a47aad81d7a
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|390C / Donor, Lineage, Cell class and subclass (all cells)

EML4 ST3GAL3 XKR6 NR3C1 CNOT6L ARHGEF39

2.73e-051691546cfc9ff103d13a2d5eacc457e800f53fdd29f7738
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)|Children_(3_yrs) / Lineage, Cell type, age group and donor

NCAM1 RET PTPRN CADPS BAMBI UNC80

2.73e-051691546b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Gfra2_(Zona_Incerta,_ventral_part_(ZIV))-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MYO1A ORC1 ATP6V0A4 PRDM12

2.91e-05511544734b7ba494e57a0958999581c805eb90b9bbbd5a
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Gfra2_(Zona_Incerta,_ventral_part_(ZIV))|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MYO1A ORC1 ATP6V0A4 PRDM12

2.91e-05511544622a588dcf6f70c5e6b7133678c00fc68d70d6b5
ToppCellControl-B_naive-1|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SLF1 WASHC4 DSP ARHGEF18 RACK1 MACF1

2.91e-051711546d18855b24aadea38fd1e4592f945cf15b85e05f1
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

DNHD1 TSHZ3 PDK4 KIF1B NEB C3

3.01e-051721546f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AZI2 NR3C1 ZBED6 NUFIP2 MACF1 DMD

3.42e-051761546749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

EML4 ST3GAL3 XKR6 NR3C1 CNOT6L ARHGEF39

3.42e-051761546437cfc5e06416bb0fc76d1f9dc106f74e279e880
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-D_cells_(SST+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DSP NEB PTPRN CADPS UGT2B7 CNGA3

3.53e-0517715468dbef0005095c01a806d8c7f723dc48a4650efec
ToppCelldroplet-Kidney-KIDNEY-1m-Lymphocytic-T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF18 NEB KLRK1 SACS IKBKE BAMBI

3.53e-05177154636da06ca9577cdb7c7b5114e604f6546b9765c08
ToppCellwk_20-22-Hematologic-Meg-ery-Platelet|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PLEKHF2 RIOK3 RYR3 BTK GMPR MTCL1

4.00e-051811546724efbc200e8388829bc7d81830c2689a95fa838
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN TSHZ2 CHRM2 RYR3 GMPR ADGRE5

4.13e-051821546d3a037268f026eb2f84428b1821022503cef7756
ToppCellB_cells-ISG-high_B_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

DSP TDRD7 ZBP1 RASGRP3 BTK GMPR

4.25e-051831546dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCellCOVID-19-Heart-CM_4|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRAP PDK4 NCAM1 CADPS RASGRP3 DMD

4.25e-0518315462902b6e8aa9a6f62bc1a792c971ab7f651a8e676
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRAP PDK4 NCAM1 CHRM2 CADPS DMD

4.52e-051851546549eeb521c3985bff396ea0f202db21822efa51f
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PDK4 AKR1D1 NCAM1 MDN1 SACS DMD

4.80e-05187154669b47f00598d647e2a99427ebddf42c339428e47
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

EML4 NF1 ZBED6 NUFIP2 MACF1 DYNC1H1

4.94e-051881546ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DSP PLEKHF2 RACK1 RASGRP3 BTK UGT2B17

5.09e-051891546b4237437452f86e745b91285980c48a02a95f4c6
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RET NEB PKD1L3 PTPRN CADPS UNC80

5.24e-05190154640d8b3403f4e38436b961cd3a2e69826cbae3042
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ2 ABCC9 RET MDN1 ADGRE5 DMD

5.24e-051901546048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RET NEB PKD1L3 PTPRN CADPS UNC80

5.24e-051901546a9a705455019e28d655636de73b07540798f82e6
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine-Neuroendocrine_L.0.7.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RET NEB PKD1L3 PTPRN CADPS UNC80

5.24e-051901546f6cbf6d292f488ada5f7581e1dceba6198b933d1
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ2 ABCC9 RET MDN1 ADGRE5 DMD

5.24e-0519015461121eb607a984c59fbffe7220837fc178745aa55
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MRC1 PDK4 KIF1B RYR1 MAFB ADGRE5

5.24e-0519015462d54fca50593fbd11fe13fc2bfaf937a05db776d
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

MRC1 RELN TSHZ2 DSP NCAM1 RET

5.24e-0519015469ce301841ce9486701fa28eb2a9929e35d476878
ToppCellCOVID-19-Heart-CM_4|Heart / Disease (COVID-19 only), tissue and cell type

NRAP PDK4 CADPS RASGRP3 CEP70 UGT2B7

5.24e-0519015463729648a17093b438398b82e32bbccc3af7b8c5d
ToppCellcellseq-Epithelial-Epithelial_Neuro-Secretory-PNEC-PNEC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RET NEB PTPRN CADPS BAMBI UNC80

5.40e-051911546146cfd4daa2878536b4f381564c787919ad855a8
ToppCelldroplet-Heart-nan-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRAP DSP PDK4 CHRM2 RYR3 TNNI3K

5.40e-05191154697fb4232417a39801e87725755fd16a57c250209
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

NRAP NCAM1 CHRM2 CADPS RASGRP3 DMD

5.40e-0519115465d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCellcellseq-Epithelial-Epithelial_Neuro-Secretory-PNEC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RET NEB PTPRN CADPS BAMBI UNC80

5.40e-05191154612ea07565dc0e62cade9fbab4a2d763e47a341e3
ToppCell(5)_Epi_basal|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

ENC1 CARS1 KRT23 UGT2B17 GMPR DMD

5.40e-0519115466bda3d5a8a391d41bb4d65872492e6c094bcc4d4
ToppCelldroplet-Heart-nan-3m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRAP DSP PDK4 CHRM2 RYR3 TNNI3K

5.40e-05191154664070a309d7e3f6001272409ab9ce206d0e7d73f
ToppCell(11)_FOXN4+-(0)_Reference|(11)_FOXN4+ / shred by cell type by condition

MYBBP1A PKD1L1 AKR1D1 NCAM1 ACTL6A ST3GAL3

5.55e-051921546ef06f96b934dd05b40025f8215b6d919d3a17045
ToppCell11.5-Airway-Epithelial-Epithelial|Airway / Age, Tissue, Lineage and Cell class

CHRM2 PPP2R2C NWD2 PTPRN CADPS C2orf80

5.55e-051921546a77d3692ff02ef7e066a9bd9e22725055a25c4d4
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COPA KIF1B NEB PTPRN GMPR UNC80

5.72e-051931546471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCelldroplet-Pancreas-Endocrine-21m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COPA KIF1B NEB PTPRN GMPR UNC80

5.88e-0519415463a3ecedcdc7691cf21775818b598208fcb980c29
ToppCell(4)_Endothelial_cells-(42)_EC-sinusoidal|(4)_Endothelial_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

MRC1 ENC1 ABCC9 RALGAPA2 GMPR MAFB

5.88e-0519415464199900d16623eca02d674d5ada7f0989e47955e
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

NRAP NCAM1 CHRM2 CADPS RASGRP3 DMD

5.88e-051941546c3535f7cc0076653c72db582047cff053c322397
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COPA KIF1B NEB PTPRN GMPR UNC80

5.88e-0519415460b023de48ed8a550d169bbe954881eb04bf4f981
ToppCell18-Airway-Epithelial-Epithelial|Airway / Age, Tissue, Lineage and Cell class

NCAM1 RET CHRM2 NWD2 PTPRN CADPS

5.88e-051941546d3c90e1f1228f8ba0ba56105c6cf4f302c388f28
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ3 TSHZ2 ABCC9 NCAM1 LOXHD1 ADGRE5

6.05e-051951546803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

NRAP PDK4 NCAM1 CHRM2 UGT2B7 DMD

6.05e-05195154675fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ3 TSHZ2 ABCC9 NCAM1 LOXHD1 ADGRE5

6.05e-0519515464f70157d42a16ff0259bc24a62803c4df4285c44
ToppCellCOVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type

NRAP PDK4 NCAM1 CHRM2 CADPS DMD

6.05e-051951546f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ3 TSHZ2 ABCC9 NCAM1 LOXHD1 ADGRE5

6.23e-051961546a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ3 TSHZ2 ABCC9 NCAM1 ADGRE5 DMD

6.23e-051961546fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ3 TSHZ2 ABCC9 NCAM1 ADGRE5 DMD

6.23e-051961546802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ3 TSHZ2 ABCC9 NCAM1 LOXHD1 ADGRE5

6.23e-0519615463e6803587d8566fd08cb8b290be3b6461743d79c
ToppCellBronchial-NucSeq-Immune_Myeloid-Mast_cell-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RYR3 TNNI3K CADPS BTK GMPR MTCL1

6.40e-051971546bed8a9b73af5caee51b1232b31c24a59353658df
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ3 TSHZ2 ABCC9 NCAM1 LOXHD1 ADGRE5

6.40e-051971546b349f8e96d61a4c296af64711e11fc44459a9413
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ3 TSHZ2 ABCC9 NCAM1 LOXHD1 ADGRE5

6.40e-0519715466d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCellBronchial-NucSeq-Immune_Myeloid-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RYR3 TNNI3K CADPS BTK GMPR MTCL1

6.40e-051971546b7d5073d44aa1e2cb83ea8d8104c5ed662665755
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ3 TSHZ2 ABCC9 NCAM1 LOXHD1 ADGRE5

6.40e-051971546c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCellBronchial-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MRC1 RELN TSHZ2 PKD1L3 LOXHD1 RASGRP3

6.59e-051981546fc4b7c3ad52bc5c8b40fa04a156bfbb58afa2872
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alv_MT|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MRC1 RYR1 ORAI1 MAFB ADGRE5 C2orf80

6.59e-0519815462b724d2a36843801984d46a969d33149b76c9771
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating-cycling_dorsal_progenitors|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

MELK ARHGEF39 CEP135 CEP70 ZMYM1 CDC27

6.59e-0519815465f0964c3aa7e1dc52cbb46e754078920b65bcb88
ToppCellTransplant_Alveoli_and_parenchyma-Endothelial-Lymphatic|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X

MRC1 RELN TSHZ2 DSP RASGRP3 C1QBP

6.59e-0519815467a99c341736a4a2ac48ef8e2f7951f21a7378946
ToppCellBronchial-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MRC1 RELN TSHZ2 PKD1L3 LOXHD1 RASGRP3

6.59e-051981546b3a020522e064bb61949d38e442f24026e339364
ToppCellRV-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

MYO1A PDK4 CHRM2 DMD GABRR3

6.61e-0512215451cb1dd03b2aaedbe04f3ed907568c3b7f54767b3
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-GABAergic_neurons|GW23 / Sample Type, Dataset, Time_group, and Cell type.

TSHZ3 RELN DLGAP4 NCAM1 SACS CADPS

6.96e-052001546c6bbd33bca86ac7a76a7ba704b3e141237d04549
ToppCellTransverse-Dendritic_cell-cycling_DCs|Transverse / Region, Cell class and subclass

OTOA MRC1 MELK ORC1 ARHGEF39 MAFB

6.96e-052001546f588d8889f351c797963616a3575fa43efd46b9a
ToppCellTransverse-(5)_Dendritic_cell-(52)_cycling_DCs|Transverse / shred on region, Cell_type, and subtype

OTOA MRC1 MELK ORC1 ARHGEF39 MAFB

6.96e-05200154651e643d48b5e97a0e117b578a6ea7d429c6cdd1e
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-B_activate-7|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

OTOA DSP RASGRP3 RAB15 DMD

1.18e-04138154576be06136c83c167cedece7515228ed4d29dd1f0
ToppCellFrontal_cortex-Macroglia-OLIGODENDROCYTE-O2-Tnr-Oligodendrocyte.Tnf.Klk6_(Klk6)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

NRAP PKD1L1 AKR1D1 KLRK1

1.26e-04741544a53f2e1f1044f3745a1eff5ba6275c8f1fbf3ae0
ToppCellFrontal_cortex-Macroglia-OLIGODENDROCYTE-O2-Tnr-Oligodendrocyte.Tnf.Klk6_(Klk6)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

NRAP PKD1L1 AKR1D1 KLRK1

1.26e-04741544ae547cb8bbd780b19d9c6b555c27dad932dcc753
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PKD1L1 RET MELK GFAP ORC1

1.35e-041421545e160f35b3c18e77c4107fe96db5f56227c91785e
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Glra3|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TSHZ3 RELN TMTC2 TNNI3K MAFB

1.59e-04147154550e86860a94be103092c40e39a172eac92372f0d
ToppCellLA-15._Ventricular_Cardiomyocyte_III|LA / Chamber and Cluster_Paper

NRAP PPP2R2C ARHGEF39 UGT2B7 DMD

1.59e-0414715458970eb6b82589f39439c61a57d999661ec8342de
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SPEG CHRM2 NWD2 DMD GNB3

2.03e-041551545cd7d95cbcad248670e531d80bb83c55e36ebc573
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TSHZ3 TMTC2 TECTA BAMBI MAFB

2.16e-041571545a98d06cef80bfe8481b0940abce2b29675e45812
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

WASHC4 DSP ARHGEF18 RACK1 RASGRP3

2.36e-0416015457ad065337ac802de52c15ee715f6b78a3eed0cef
ToppCelldroplet-Lung-nan-3m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIGB MELK ORC1 GPR68 EFCAB7

2.36e-0416015458a7a73b0ee1877fe02d47f745d36ae2858b529e1
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

SPEG RYR3 SACS UGT2B7 DMD

2.43e-04161154564891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCA13 TECTA NEB NWD2 UNC80

2.50e-041621545bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellCOVID-mono3|COVID / Condition, Cell_class and T cell subcluster

OTOA TBC1D30 RASGRP3 C3 UNC80

2.57e-0416315456ab4cbcd411b40920b81162c0f4b03ea67408f52
ToppCellCOVID-mono3-|COVID / Condition, Cell_class and T cell subcluster

OTOA TBC1D30 RASGRP3 C3 UNC80

2.57e-04163154526661c7a3a0a449ed32d4b3b28fc2fc0b237025d
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

RET PTPRN CADPS BAMBI UNC80

2.64e-041641545be49af6335f2505065cde2cb9800e4a5516811b1
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

RET PPP2R2C PTPRN ATP6V0A4 C2orf80

2.72e-0416515459795ce31689bc63f5a2d68725ef00b23a90c3846
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

TSHZ2 PDK4 CHRM2 ARHGEF39 DMD

2.79e-04166154594636dbc039f794c735960c3425e00bdd5523602
ToppCellnormal-na-Lymphocytic_B-B_atypical-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

ENC1 NEB KRT23 RASGRP3 ADGRE5

2.79e-04166154530a180b67572c3f4fb3a291f271f855e1b20005e
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

NR3C1 NEB UBASH3A TDRD7 CDC27

2.87e-041671545c0c944eae0514dc8e00d0c2892a0792e157695ec
ToppCellControl-B_intermediate-1|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SLF1 WASHC4 ARHGEF18 MDN1 RACK1

2.87e-041671545948504367ecf58144d9dd74d2ec531358fc4b309
ToppCellfacs-Heart-LA-3m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PGBD1 UBASH3A KLRK1 ARHGEF39 GPR68

2.95e-04168154524d1e0a05cda09ee3b80208d75cb2b601023f3bf
Drugdihydropyridine

BIN1 PKD1L3 CHRM2 RYR1 RYR3 ITPR3 ORAI1 SLC9A1 DMD GNB3

7.62e-0719315310CID000104822
DrugClorocruoro Hem

RET SERPINA2 CHRM2 CHRNA4 RYR1 RYR3 ITPR3 MAPK6

1.86e-061231538CID003518809
DrugNSC692750

GFAP RYR1 RYR3

5.86e-0661533CID000078910
Druglorcaserin

UGT2B7 UGT2B15 UGT2B17

5.86e-0661533ctd:C506658
Drugtestosterone glucuronide

NR3C1 NF1 UGT2B7 UGT2B15 UGT2B17

7.91e-06411535CID000108192
Drugethyl iodoacetate

PTPRN UGT2B7 UGT2B15 BAMBI GMPR

8.93e-06421535CID000012183
Drug[[(2R,3S,4R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl hydrogen phosphate

RYR1 RYR3 ITPR3

1.02e-0571533CID009547999
DrugBr2BAPTA

RYR1 RYR3 ITPR3

1.02e-0571533CID003081001
Drugethosuximide

PKD1L3 RYR1 RYR3 ITPR3 ORAI1 ADGRE5

1.06e-05741536CID000003291
Drug5 alpha-dihydrotestosterone

AKR1D1 ACTL6A NR3C1 SERPINA2 BBS9 ORC1 UGT2B7 UGT2B15 UGT2B17 MAPK6 IMMT

1.23e-0532315311CID000000015
DrugAC1MMVSM

AKR1D1 NCAM1 NR3C1 DMD

1.57e-05231534CID003292433
DrugCinildipine

PKD1L3 RYR1 RYR3 ITPR3 ORAI1

3.72e-05561535CID000002752
Drugcaged InsP3

PKD1L3 RYR1 RYR3 ITPR3

4.09e-05291534CID000122248
Drugmanidipine

ACTL6A PKD1L3 RYR1 RYR3 ITPR3 ORAI1

4.43e-05951536CID000004008
Drug5'-adenylyl (beta,gamma-methylene)diphosphonate

RYR1 RYR3

4.49e-0521532ctd:C005147
Drugpropofol

COPA CHRM2 CHRNA4 RYR1 RYR3 UGT2B7 UGT2B15 DMD

4.65e-051911538CID000004943
DrugR 478

RYR1 RYR3 ITPR3

4.72e-05111533CID000084223
Drug8-amino-cADPR

RYR1 RYR3 ITPR3

4.72e-05111533CID003081323
Drugnilvadipine

PKD1L3 RYR1 RYR3 ITPR3 ORAI1

5.20e-05601535CID000004494
Drug1,8-dinitropyrene

SLC9A1 PTPRN BTK GMPR

5.36e-05311534CID000039185
Drugvalproate

RELN NCAM1 RET PKD1L3 RYR1 RYR3 ITPR3 UGT2B7 UGT2B15 ADGRE5 MAPK6

5.59e-0538115311CID000003121
Drugarabinosyladenine

ZC3H14 DIABLO CARS1 NARS1 RIOK3 ABCC9 ACTL6A PKD1L3 CHRM2 RYR1 RYR3 ITPR3 NF1 NME5 C3 MAPK6

5.70e-0576215316CID000000191
Drugnicardipine

PKD1L3 CHRM2 CHRNA4 RYR1 RYR3 ITPR3 ORAI1

5.74e-051451537CID000004473
DrugDantrolene-13C3

TECTA PKD1L3 RYR1 RYR3 ITPR3 ORAI1 DMD

5.74e-051451537CID000002951
DrugNaltrexone hydrochloride dihydrate [16676-29-2]; Up 200; 9.6uM; HL60; HG-U133A

ZC3H14 RIOK3 ACTL6A AZI2 NR3C1 TSEN2 ORC1 PDCD11

5.78e-0519715381363_UP
DrugMetampicillin sodium salt [6489-61-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A

EML4 DLGAP4 MLXIP BBS9 IKBKE C3 ADGRE5 ULK2

5.99e-0519815382286_DN
Druggadolinium

PKD1L3 GFAP RYR1 RYR3 ITPR3 ORAI1 NF1 SACS

6.20e-051991538CID000023982
Druglercanidipine

PKD1L3 RYR1 RYR3 ITPR3 ORAI1

6.59e-05631535CID000065866
DrugCNS 1145

PKD1L3 RYR1 RYR3 ITPR3

6.89e-05331534CID000190902
DrugIHC-64

PKD1L3 RYR1 RYR3 ITPR3

6.89e-05331534CID000162753
DrugBAPTA

CHRM2 CHRNA4 RYR1 RYR3 ITPR3 ORAI1 SLC9A1 SACS GPR68 MAPK6

7.07e-0532415310CID000104751
DrugBay K 8644

PKD1L3 CHRM2 RYR1 RYR3 ITPR3 ORAI1 NF1

7.11e-051501537CID000002303
Drugsuccinylcholine

CHRM2 CHRNA4 RYR1 RYR3 DMD

7.11e-05641535CID000005314
Drugprocaine

PKD1L3 CHRM2 CHRNA4 RYR1 RYR3 ITPR3 ORAI1

8.05e-051531537CID000004914
DrugNSC299933

RYR1 RYR3 ORAI1

8.10e-05131533CID000431902
DrugAC1NOWCJ

NARS1 UGT2B7 UGT2B15 UGT2B17

8.73e-05351534CID005120112
Druggallopamil

PKD1L3 RYR1 RYR3 ITPR3 ORAI1

8.86e-05671535CID000001234
Drug(+/-)-Huperzine A

ABCA2 CHRM2 GFAP PSMD14

9.77e-05361534CID000001253
DrugAC1L2AC7

PKD1L3 RYR1 RYR3 ITPR3 ORAI1

1.02e-04691535CID000068733
Drug1,3-dinitropyrene

PTPRN BTK GMPR

1.28e-04151533CID000053230
DrugGvapspat amide

RYR1 RYR3 ITPR3

1.28e-04151533CID000125015
DrugCAS 298-57-7

PKD1L3 RYR1 RYR3 ITPR3 ORAI1

1.33e-04731535CID000002761
DrugNSC-61590

NCAM1 NR3C1

1.34e-0431532CID000052795
Drugoxazepam glucuronide

UGT2B7 UGT2B15

1.34e-0431532ctd:C026256
Drugcis-diammineplatinum(II

RYR1 RYR3

1.34e-0431532CID000159790
Drug2-hydroxyheptanoic acid

RYR1 RYR3

1.34e-0431532CID002750949
Drug8N3-cADPR

RYR1 RYR3

1.34e-0431532CID000127713
Drugaminodantrolene

RYR1 RYR3

1.34e-0431532CID009570289
Drugmaltose tetrapalmitate

NR3C1 RYR1

1.34e-0431532CID003035236
Drug2-hydroxycarbazole

RYR1 RYR3

1.34e-0431532CID000093551
Drug1,1'-diheptyl-4,4'-bipyridinium

RYR1 RYR3

1.34e-0431532CID000080262
Drugflubendiamide

RYR1 RYR3

1.34e-0431532CID011193251
DrugRyanodyl 3-(pyridine-3-carboxylate

RYR1 RYR3

1.34e-0431532CID005748312
DrugNAADP

RYR1 RYR3 ITPR3 IMMT

1.34e-04391534CID000123952
DrugN-methyl-DL-aspartic acid

RELN NCAM1 NR3C1 TECTA PKD1L3 CHRM2 GFAP CHRNA4 RYR1 RYR3 ITPR3 ORAI1 BAMBI MAPK6

1.40e-0465515314CID000004376
DrugAC1L9GJJ

CHRM2 ITPR3 NF1 BTK

1.48e-04401534CID000444570
DrugPhenoxybenzamine

NCAM1 NR3C1 GFAP

1.56e-04161533ctd:D010643
Drug2-AF

UGT2B7 UGT2B15 UGT2B17 GMPR

1.64e-04411534CID000005800
DiseaseMyopathy, Centronuclear, Autosomal Recessive

BIN1 SPEG RYR1

5.45e-0741533C0410204
DiseaseAutosomal Recessive Centronuclear Myopathy

BIN1 SPEG RYR1 ORAI1

9.07e-07151534C3645536
Diseasedeoxycholic acid glucuronide measurement

UGT2B7 UGT2B15 UGT2B17

7.51e-0681533EFO_0800575
DiseaseIntellectual Disability

ZC3H14 PIGB ACTL6A ST3GAL3 TSEN2 NF1 SACS MACF1 TFB2M TSEN15 DYNC1H1

2.32e-0544715311C3714756
DiseaseX-15492 measurement

AKR1D1 UGT2B15

2.67e-0521532EFO_0800752
DiseaseAutosomal Dominant Myotubular Myopathy

BIN1 RYR1 ORAI1

3.76e-05131533C3661489
DiseaseCentronuclear myopathy

BIN1 RYR1 ORAI1

3.76e-05131533C0175709
DiseaseX-linked centronuclear myopathy

BIN1 RYR1 ORAI1

3.76e-05131533C0410203
DiseaseMyopathy, Centronuclear, 1

BIN1 RYR1 ORAI1

3.76e-05131533C4551952
DiseaseX-19141 measurement

UGT2B7 UGT2B15 UGT2B17

3.76e-05131533EFO_0800799
DiseaseCongenital Structural Myopathy

BIN1 RYR1 ORAI1

3.76e-05131533C0752282
DiseaseMyopathy, Centronuclear, Autosomal Dominant

BIN1 RYR1 ORAI1

4.77e-05141533C1834558
DiseaseTubular Aggregate Myopathy

BIN1 RYR1 ORAI1

4.77e-05141533C0410207
DiseaseNonsyndromic Deafness

OTOA DIABLO TMTC2 TECTA LOXHD1

6.55e-05811535C3711374
DiseasePheochromocytoma, Extra-Adrenal

KIF1B RET NF1

7.29e-05161533C1257877
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR1 RYR3

7.99e-0531532DOID:3529 (implicated_via_orthology)
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR1 RYR3

7.99e-0531532DOID:8545 (implicated_via_orthology)
Diseasecholic acid glucuronide measurement

UGT2B15 UGT2B17

7.99e-0531532EFO_0800574
DiseaseCongenital Fiber Type Disproportion

BIN1 RYR1 ORAI1

1.05e-04181533C0546264
Diseaseetiocholanolone glucuronide measurement

AKR1D1 UGT2B15 UGT2B17

1.25e-04191533EFO_0800362
DiseasePheochromocytoma

KIF1B RET NF1

1.25e-04191533C0031511
DiseaseX-25937 measurement

UGT2B15 UGT2B17

1.59e-0441532EFO_0800937
DiseasePontocerebellar Hypoplasia Type 2

TSEN2 TSEN15

1.59e-0441532C2932714
DiseaseX-17340 measurement

AKR1D1 UGT2B15

1.59e-0441532EFO_0800773
Diseasehearing impairment

OTOA MYO1A DIABLO TECTA LOXHD1

1.62e-04981535C1384666
DiseaseX-24947 measurement

UGT2B7 UGT2B15 UGT2B17

1.96e-04221533EFO_0800910
DiseaseHereditary Paraganglioma-Pheochromocytoma Syndrome

KIF1B RET NF1

2.24e-04231533C1708353
Diseaseblood strontium measurement

GNPDA1 PPP2R2C MTCL1

3.65e-04271533EFO_0021531
DiseaseMental Depression

RELN NCAM1 NR3C1 CHRM2 GFAP CHRNA4 GNB3

3.76e-042541537C0011570
DiseasePontocerebellar hypoplasia type 2

TSEN2 TSEN15

3.95e-0461532cv:C2932714
DiseaseMULTIPLE PTERYGIUM SYNDROME, LETHAL TYPE

NEB RYR1

3.95e-0461532C1854678
DiseaseMicrocephaly

CARS1 TSEN2 ORC1 DYNC1H1

4.13e-04671534C0025958
DiseaseX-24574 measurement

UGT2B15 UGT2B17

5.51e-0471532EFO_0800897
DiseaseSevere Congenital Microcephaly

TSEN2 ORC1 DYNC1H1

5.52e-04311533C3853041
Diseasepain

PGBD1 NCAM1 PKD1L3 MIPOL1 NUFIP2 MACF1

5.72e-041961536EFO_0003843
DiseaseMicrolissencephaly

TSEN2 ORC1 DYNC1H1

6.65e-04331533C1956147
DiseaseNonsyndromic genetic hearing loss

OTOA DIABLO TECTA LOXHD1

6.67e-04761534cv:C5680182
DiseaseFEV/FEC ratio

TSHZ3 WWC3 DSP EML4 SPEG KIF1B CAPZB ARHGEF18 NCAM1 NR3C1 NEB TSEN2 CADPS RASGRP3 MAFB MTCL1

6.68e-04122815316EFO_0004713
DiseaseDepressive disorder

RELN NCAM1 NR3C1 CHRM2 GFAP CHRNA4 GNB3

8.07e-042891537C0011581
DiseaseBipolar Disorder

RELN ABCA13 NCAM1 NR3C1 CHRM2 GFAP PPP2R2C RACK1 GNB3

8.96e-044771539C0005586
Diseaseplasma clozapine-to-N-desmethylclozapine ratio measurement

UGT2B7 UGT2B15

9.39e-0491532EFO_0600040
DiseaseX-12844 measurement

AKR1D1 UGT2B15

9.39e-0491532EFO_0021339
Diseasetestosterone measurement

HAUS6 TSHZ2 EML4 DLGAP4 AKR1D1 SNUPN NR3C1 SERPINA2 NF1 NUFIP2 CEP70 UGT2B7 UGT2B15 UGT2B17 MACF1 MAFB

9.93e-04127515316EFO_0004908
DiseaseSeizures

PIGB GFAP CHRNA4 MACF1 GNB3 TSEN15

9.95e-042181536C0036572
Disease4-androsten-3alpha,17alpha-diol monosulfate (3) measurement

UGT2B15 UGT2B17

1.17e-03101532EFO_0022090
Disease3-methyl-2-oxobutyrate measurement

NR3C1 ANKRD50

1.17e-03101532EFO_0021020
DiseaseImmature Reticulocyte Fraction Measurement

RIOK3 GMPR

1.17e-03101532EFO_0009253
Diseasefear of medical pain measurement

WWC3 TNNI3K

1.17e-03101532EFO_0008339
Diseaseosteoarthritis, knee, body mass index

PKD1L3 MAFB MAPK6

1.26e-03411533EFO_0004340, EFO_0004616
DiseaseDNA repair protein RAD51 homolog 4 measurement

UGT2B15 UGT2B17

1.42e-03111532EFO_0801531
Diseaselevel of Sterol ester (27:1/20:5) in blood serum

CPT1A NWD2

1.42e-03111532OBA_2045197
Diseaseresponse to virus

BBS9 MAFB

1.42e-03111532GO_0009615
Diseaseosteoarthritis, knee

SNUPN XKR6 ITPR3 SBNO1 MAPK6

1.43e-031581535EFO_0004616
Diseasedilated cardiomyopathy (is_implicated_in)

DSP ABCC9 DMD

1.45e-03431533DOID:12930 (is_implicated_in)
Diseasesurvival time, lung adenocarcinoma

CAPZB NWD2

1.70e-03121532EFO_0000571, EFO_0000714
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

ITPR3 PPP2R2C

1.70e-03121532DOID:1441 (implicated_via_orthology)
DiseaseCongenital myopathy (disorder)

NEB RYR1

1.70e-03121532C0270960
Disease5alpha-androstan-3beta,17beta-diol monosulfate (2) measurement

UGT2B15 UGT2B17

1.70e-03121532EFO_0800291
Diseasecholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement

XKR6 CPT1A UGT2B15 UGT2B17 MACF1 MAFB

1.73e-032431536EFO_0004612, EFO_0020944
DiseaseMajor Depressive Disorder

RELN NCAM1 NR3C1 GFAP IKBKE GNB3

1.73e-032431536C1269683
DiseaseMood Disorders

RELN NCAM1 NR3C1 CHRM2 GNB3

1.87e-031681535C0525045
Diseaseamyotrophic lateral sclerosis (biomarker_via_orthology)

KIF1B C3

2.01e-03131532DOID:332 (biomarker_via_orthology)
Diseasecerotoylcarnitine (C26) measurement

ST3GAL3 CPT1A

2.01e-03131532EFO_0800542
Diseaseandrostenediol (3alpha, 17alpha) monosulfate (3) measurement

UGT2B15 UGT2B17

2.01e-03131532EFO_0800293
Diseasetotal cholesterol measurement, triglyceride measurement, low density lipoprotein cholesterol measurement, high density lipoprotein cholesterol measurement

CPT1A NF1 UGT2B15

2.11e-03491533EFO_0004530, EFO_0004574, EFO_0004611, EFO_0004612
Disease5alpha-androstan-3alpha,17alpha-diol monosulfate measurement

UGT2B15 UGT2B17

2.33e-03141532EFO_0800283
DiseaseNonsyndromic Hearing Loss and Deafness, Autosomal Recessive

OTOA TECTA LOXHD1

2.37e-03511533cv:CN043650
DiseaseUnipolar Depression

RELN NCAM1 NR3C1 GFAP IKBKE GNB3

2.38e-032591536C0041696
DiseaseStreptozotocin Diabetes

PDK4 CPT1A CHRM2 SLC9A1

2.45e-031081534C0038433
DiseaseDiabetes Mellitus, Experimental

PDK4 CPT1A CHRM2 SLC9A1

2.45e-031081534C0011853
DiseaseAlloxan Diabetes

PDK4 CPT1A CHRM2 SLC9A1

2.45e-031081534C0002152
Diseasealkaline phosphatase measurement

ST3GAL3 XKR6 CPT1A PKD1L3 ZBP1 NWD2 NF1 NUFIP2 UGT2B7 UGT2B15 UGT2B17 MACF1 MAFB

2.49e-03101515313EFO_0004533
Diseasedepressive disorder (biomarker_via_orthology)

NCAM1 NR3C1 CHRM2

2.51e-03521533DOID:1596 (biomarker_via_orthology)
DiseaseAlcoholic Intoxication, Chronic

CARS1 NCAM1 CHRM2 GFAP CHRNA4 RACK1

2.82e-032681536C0001973
Diseasefactor VII activating protease measurement

NRAP MELK USP32

2.94e-03551533EFO_0009368
DiseasePontoneocerebellar hypoplasia

TSEN2 TSEN15

3.06e-03161532cv:C1261175
Diseasetrait in response to apixaban

NELFCD NR3C1 C3 DMD

3.08e-031151534OBA_2050328
Diseasechronic obstructive pulmonary disease

TSHZ3 DSP EML4 SPEG KIF1B CAPZB CHRNA4 RASGRP3 MAFB MTCL1

3.24e-0368815310EFO_0000341
Diseasecholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

XKR6 CPT1A UGT2B15 UGT2B17 MACF1 MAFB

3.26e-032761536EFO_0004612, EFO_0020943
Diseaseomega-3 polyunsaturated fatty acid measurement

CPT1A UGT2B15 UGT2B17 MAFB

3.37e-031181534EFO_0010119
DiseaseHuntington Disease

RELN DIABLO

3.45e-03171532C0020179
Diseasemajor depressive disorder (is_implicated_in)

NR3C1 CHRM2

3.45e-03171532DOID:1470 (is_implicated_in)
Diseaselupus nephritis (is_marker_for)

NR3C1 C3

3.45e-03171532DOID:0080162 (is_marker_for)
DiseaseCharcot-Marie-Tooth disease type 2

KIF1B DYNC1H1

3.45e-03171532cv:C0270914
DiseaseSjogren syndrome

ATG5 RELN RASGRP3

3.77e-03601533EFO_0000699
Disease5alpha-androstan-3alpha,17beta-diol monosulfate (1) measurement

UGT2B15 UGT2B17

3.87e-03181532EFO_0800288
Diseasebipolar disorder (is_marker_for)

RELN CHRM2

4.31e-03191532DOID:3312 (is_marker_for)
DiseaseCOVID-19 (is_marker_for)

GFAP BTK C3

4.32e-03631533DOID:0080600 (is_marker_for)
Diseaseandrosterone glucuronide measurement

UGT2B15 UGT2B17

4.77e-03201532EFO_0800317

Protein segments in the cluster

PeptideGeneStartEntry
IMFSSLYRISKEHWN

PPP2R5E

386

Q16537
KLSISSDNMQHAYWE

AZI2

211

Q9H6S1
SWTYDKAKIDLVNMH

CHRNA4

181

P43681
ETYMSADDLRINLWH

PPP2R2C

186

Q9Y2T4
IYTSSKEDRNAWMAH

ARHGEF18

766

Q6ZSZ5
MAHYDLAISVALQWL

C2orf80

41

Q0P641
LNTDSLDWALYDHLM

C1QBP

226

Q07021
WYSKHMTRSQAEQLL

BTK

281

Q06187
LYHKSNLCATWEAME

AKR1D1

141

P51857
SALKYHLQMLAAENW

ARMH2

196

H3BNL8
KLETMYNHWTWELRS

GVINP1

1746

Q7Z2Y8
WDSFQAILDHTYKMH

ACTL6A

96

O96019
LMAHYDVEDWKLTLI

ADGRE5

536

P48960
LEEKKHYLMWGLSSD

C3

1596

P01024
VAHLWEYVMSIDSLQ

CPT1A

481

P50416
QHLYMLAKSLEETWS

ABCA13

3036

Q86UQ4
MVAYLETQLADWIHS

BCL2L2

126

Q92843
HKLQYLTHADWIIAM

ABCC9

871

O60706
IMTVLYWHISRASKS

CHRM2

201

P08172
ITELYHAVWTKNMSL

ANKRD50

366

Q9ULJ7
KHQEYLKLETTWMTA

DIABLO

146

Q9NR28
TCWDHPKMTELYQSL

DMD

3081

P11532
TLSQAMYEGHWLVLD

DNHD1

4141

Q96M86
MLETPLQWLSEHLSY

ATG5

246

Q9H1Y0
HYKLTSTVMLWLQTN

CAPZB

166

P47756
SMKFDELYHLKANSW

DLGAP4

896

Q9Y2H0
LMSTDQEELSRWYHS

ARHGEF39

311

Q8N4T4
IMVTSDDKSSQYVWH

NWD2

1371

Q9ULI1
SSERSYQHIMKWVSD

RAB15

91

P59190
VLSSYWSQHLGKKEM

PBLD

236

P30039
AMLWDLNEGKHLYTL

RACK1

216

P63244
YALRWKELEMHSLAL

MTCL1

996

Q9Y4B5
VEMKEIYTSNHIWTL

ITPR3

1426

Q14573
MEDLISLWQYDHLTA

MELK

301

Q14680
WYIQSLMDLVEFHEK

PDK4

91

Q16654
HYQWSALVKMSENEL

RAD9B

61

Q6WBX8
DKTSAHSQRALYSWM

OTOA

221

Q7RTW8
TWLTDRMDLQLHIYQ

CADPS

1271

Q9ULU8
SWHDDLTQYVISQEM

PTPRN

96

Q16849
TEKSTKHWFSIYQML

MDN1

3831

Q9NU22
TEQKTHLEDLYWMAS

MAFB

76

Q9Y5Q3
PMSVEHADIWVKSYS

IL15RA

36

Q13261
LEQMIAHTTWRDLFY

NELFCD

146

Q8IXH7
MKLIILEHYSQASEW

GNPDA1

1

P46926
LHEYTVLPEDMKTQW

NRAP

656

Q86VF7
MENWSKDITHSYLEQ

MIPOL1

1

Q8TD10
HYQLMRKSQILISSW

MYO1A

716

Q9UBC5
SMSKYDLLVWFEISE

KIF1B

1246

O60333
MQSTANYLWHTDDLL

IKBKE

1

Q14164
LAWHVKTITITEMEY

LOXHD1

1891

Q8IVV2
LNEHSMQALSWRKLY

ORAI1

66

Q96D31
ILLMDETHSHIYNWE

MAPK6

341

Q16659
EDQDLLKLVKSYHWM

KLRK1

141

P26718
AMILARHKAISYWLE

NME5

81

P56597
HRDLDTWYKEQSAAM

KRT23

256

Q9C075
FWYDMAALLTTIKDT

MACF1

2136

O94854
AHQLWLSVEALKYSM

IMMT

566

Q16891
AKIYAMHWATDSKLL

GNB3

56

P16520
NLHLDDQMTLLQYSW

NR3C1

586

P04150
DASQEDHRSWMTYIK

PRDM12

151

Q9H4Q4
ASSNMHEAEEWYRSK

GFAP

246

P14136
LVSYWEKLQMFETSL

RALGAPA2

1211

Q2PPJ7
MLHIYQDVTLKWATQ

BBS9

311

Q3SYG4
AEKFWYDMAALLTTI

MACF1

6006

Q9UPN3
TGSSRLHDLYWQAMK

MYBBP1A

1126

Q9BQG0
LQYSHDAGMSWFLVK

RELN

1321

P78509
ELDLLWTHKQDIMYN

ORC1

621

Q13415
LSSLVQDDDMLYWHK

MLXIP

241

Q9HAP2
HKYITEVSRWESLMA

CEP135

856

Q66GS9
MWQLEEKLTYSHLEN

SERPINA2

286

P20848
DLMLYWKHGNKSLNT

GABRR3

211

A8MPY1
QMTHDGYLKLWQLSK

FBH1

621

Q8NFZ0
MDRHSSYIFIWLQLE

BAMBI

1

Q13145
IEMWADQLTSLKDLY

CEP70

396

Q8NHQ1
TMQITHENIYLWDIH

DOK6

156

Q6PKX4
DLWVTLHSMGYNKAL

EFCAB7

481

A8K855
VKYVIWSADMSHVAL

COPA

491

P53621
SLVSWHYCMIDIEKI

DSP

546

P15924
VEEHLWFYSRLKSMA

ABCA2

1081

Q9BZC7
GLMLDSHEELYKWFT

DYNC1H1

3041

Q14204
VTAFEKEHLWMYLQA

HAUS6

6

Q7Z4H7
YDTLHEEWSKAAPML

ENC1

361

O14682
HLDWSPDNKYIMSNS

EML4

726

Q9HC35
SMFTAIHKHYSLDDW

GMPR

71

P36959
WMDYHQKLVDQALLT

BIN1

111

O00499
TRQTWLLLHMYDSDK

C7orf50

121

Q9BRJ6
MVWKNLYIHFSEDLT

SACS

781

Q9NZJ4
KVVSDDALMHWLDQY

SBNO1

1256

A3KN83
NMFLESYKAAWILTE

RYR1

3651

P21817
MEIYSTTLWHLQKDV

CDC27

536

P30260
LWVEVYANHVLLMSD

PKD1L1

51

Q8TDX9
HIWLQSLAYCMKLEE

KIF28P

641

B7ZC32
VYAATATEKSEWMNH

PLEKHF2

111

Q9H8W4
HKKSWMEGLTLQDYS

PSMD14

221

O00487
WAKELLTSIYFLMHE

GPR68

146

Q15743
TKQLLEGIWSYLMHF

OR52I1

301

Q8NGK6
QSSHLWLAISLSAMY

OR52I2

51

Q8NH67
SYSLMRQKFQWHEAE

MRC1

1106

P22897
LWTLLVYSMLSHKEF

PIGB

346

Q92521
SKRYQHSVEWAAELM

TSEN2

101

Q8NCE0
VQKLDHWLMSNSSEL

PSAPL1

301

Q6NUJ1
LAFLMHSWKDTLDYS

CARS1

431

P49589
HSWKDTLDYSSNTME

CARS1

436

P49589
MNYSDAIVWLKEHDV

NARS1

391

O43776
MHRWYLSSTELAEKL

RASGRP3

41

Q8IV61
TYSVFKIHWLMAALA

GPR108

286

Q9NPR9
SMIVEKFTQDYLWLS

PKD1L3

876

Q7Z443
YETVRMAAIKESWTH

ST3GAL3

336

Q11203
KVLHMEPWSSFDIYT

TFB2M

261

Q9H5Q4
KHYANQLMLSEWLID

SNUPN

96

O95149
TWIHDFMSEYLIELS

TDRD7

1081

Q8NHU6
DLWARMHISSLEYAA

PGBD1

321

Q96JS3
AEMLTLHNWLSFYEK

CYB5D2

111

Q8WUJ1
LMVSDTNRLWQHYKT

CNGA3

231

Q16281
MHWDPEYSDVKLIQT

CNOT6L

361

Q96LI5
SDHVMLKSLDWNAEY

NCAM1

666

P13591
TLVHADLSEYNMLWH

RIOK3

401

O14730
THIMYKNTLWIESAN

TECTA

1866

O75443
DVWSVYIDMTIKHGS

PDCD11

1796

Q14690
EEMLQTAYNKLHTWQ

GTF2H1

526

P32780
TSLMSLAWVLASYHK

XKR6

326

Q5GH73
WYDMKTHQEVTSSRL

WASHC5

846

Q12768
SQSTHYFLMDKRWNL

UNC80

2036

Q8N2C7
HYIISWKRTSAMENI

TRAPPC11

981

Q7Z392
HLLDMDEQSKAWTIY

ZBP1

151

Q9H171
AIVYHTKEMESIWNL

NUFIP2

661

Q7Z417
IMWYKDEVLLTESSH

SPEG

1516

Q15772
SLVSWLSSIDMKYHI

RYR3

4596

Q15413
LDDLSKLCSWNHYNM

PWP2

856

Q15269
LSKLPEAEHWYMESL

TMTC2

656

Q8N394
EAEHWYMESLRSKTD

TMTC2

661

Q8N394
EYSVLLFHTEMRWLS

ZBED8

321

Q8IZ13
HLLYQLLWNMFSKEV

NF1

1251

P21359
HTTIKYFLKMWSSVS

SLC9A1

376

P19634
YLHSIAIDWDKTMRF

TBC1D30

266

Q9Y2I9
MYSEWRSLHLVIQND

RALGAPB

1

Q86X10
LSMTTISHWLANVKY

TSHZ2

891

Q9NRE2
HNVSWLYLSRLSAMK

RIOK2

146

Q9BVS4
NMLLEWTIYSHKEKF

SLF1

591

Q9BQI6
LSMTTISHWLANVKY

TSHZ3

941

Q63HK5
KWMAIESLFDHIYTT

RET

916

P07949
SLYSVLKIWHIDNQM

ZNF630

111

Q2M218
IMSQHYDAKADLWSI

ULK2

186

Q8IYT8
TWNTHVMEESLYLQL

ATP6V0A4

491

Q9HBG4
KQDETGHWISTFYML

ZBED6

641

P86452
IIDNHITLKDHWTMY

WASHC4

206

Q2M389
SEMHLKSLEFWREYQ

ZMYM1

516

Q5SVZ6
TEYSHWINMKTILEE

UGT2B15

31

P54855
AEYSHWMNIKTILDE

UGT2B7

31

P16662
LMWAYEKGHDAIVTL

TNNI3K

386

Q59H18
IHAAKQLDMQSSWVY

ZC3H14

241

Q6PJT7
EILTFSKEHYNIWMV

SLC36A4

436

Q6YBV0
VYLDLMESKSWHEVN

TSEN15

66

Q8WW01
MGHLTLEDYQIWSVK

USP32

331

Q8NFA0
DYDSLSEMQLRWHSV

WWC3

711

Q9ULE0
TEYSHWINMKTILEE

UGT2B17

31

O75795
QLYSLMSSEKWHQTI

TMEM39B

436

Q9GZU3
ESDTWVKHRMYTFSL

UBASH3A

341

P57075
ITMNHRLYTEAWDKD

NEB

2716

P20929
NALTMSKHLYTEAWD

NEB

3686

P20929