Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionribosomal protein S6 kinase activity

RPS6KA1 RPS6KA3 RPS6KA6

9.69e-0671323GO:0004711
GeneOntologyMolecularFunctionsingle-stranded DNA endodeoxyribonuclease activity

ERCC4 XRCC4 EXOG

7.69e-05131323GO:0000014
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

CACNA1S SLC11A2 GRIK1 PKD1L2 NDUFB5 ITPR2 SLC5A4 GJA1 KCNT2 P2RX3 KCNMA1 LRRC8B SLC26A11 ATP2B2 SLC9A6

2.42e-0479313215GO:0015075
GeneOntologyMolecularFunction3' overhang single-stranded DNA endodeoxyribonuclease activity

ERCC4 XRCC4

2.58e-0441322GO:1990599
GeneOntologyMolecularFunctiontransporter activity

CACNA1S SLC11A2 SLC27A6 GRIK1 ATG2A PKD1L2 NDUFB5 ITPR2 SLC5A4 GJA1 KCNT2 P2RX3 KCNMA1 LRRC8B ATG9A SLC26A11 ATP2B2 MFSD1 SLC9A6 XPR1

3.08e-04128913220GO:0005215
GeneOntologyBiologicalProcessneuromuscular process controlling balance

MYH10 MYO7A NR4A3 BCR KCNMA1 ATP2B2

8.30e-06741336GO:0050885
GeneOntologyCellularComponentneuron spine

CACNA1S MYH10 MAP1B GPER1 ITSN1 BCR CYFIP1 ARRB2 GRK2 P2RX3 ATP2B2 SLC9A6

6.15e-0824713312GO:0044309
GeneOntologyCellularComponentdendritic spine

CACNA1S MYH10 MAP1B GPER1 ITSN1 BCR CYFIP1 ARRB2 GRK2 P2RX3 ATP2B2

4.35e-0724213311GO:0043197
GeneOntologyCellularComponentdendrite

CACNA1S MYH10 MAP1B GPER1 ERO1A ITSN1 GRIK1 BCR CYFIP1 ARRB2 GRK2 P2RX3 KCNMA1 IGSF9 ATP2B2 SLC9A6

1.13e-0485813316GO:0030425
GeneOntologyCellularComponentdendritic tree

CACNA1S MYH10 MAP1B GPER1 ERO1A ITSN1 GRIK1 BCR CYFIP1 ARRB2 GRK2 P2RX3 KCNMA1 IGSF9 ATP2B2 SLC9A6

1.17e-0486013316GO:0097447
GeneOntologyCellularComponentneuron projection terminus

GPER1 ITSN1 GRIK1 CYFIP1 P2RX3 MACO1 KCNMA1 SLC9A6

1.25e-042331338GO:0044306
GeneOntologyCellularComponentciliary transition zone

NPHP1 MYO7A KIAA1549 ALPK1 CPLANE1

1.68e-04811335GO:0035869
GeneOntologyCellularComponentcilium

NPHP1 CATSPERE FBXL13 MAP1B MYO7A KIAA1549 ALPK1 CFAP54 GRK2 TTLL6 TMEM218 CFAP70 CPLANE1 DNAH6 ATP2B2 CEP19

1.91e-0489813316GO:0005929
GeneOntologyCellularComponentphotoreceptor connecting cilium

NPHP1 MYO7A KIAA1549 ALPK1

2.45e-04481334GO:0032391
GeneOntologyCellularComponentERCC4-ERCC1 complex

ERCC4 XRCC4

3.97e-0451332GO:0070522
GeneOntologyCellularComponentaxon terminus

GPER1 ITSN1 GRIK1 CYFIP1 P2RX3 KCNMA1 SLC9A6

3.99e-042101337GO:0043679
GeneOntologyCellularComponent9+0 non-motile cilium

NPHP1 MAP1B MYO7A KIAA1549 ALPK1 TTLL6

4.45e-041531336GO:0097731
GeneOntologyCellularComponentrecycling endosome

SLC11A2 GPER1 ITSN1 TUBGCP4 ATG9A BAIAP3 SLC9A6

5.56e-042221337GO:0055037
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

COPZ1 GPER1 SLC27A6 ERO1A ATG2A ITPR2 GJA1 LRPPRC PLA2G4C TMEM208 MACO1 LRRC8B HSD3B2 ATG9A UBIAD1 SLC9A6 MAN1B1 SOAT1 DGAT1

7.41e-04132713319GO:0042175
GeneOntologyCellularComponentendosome

SLC11A2 GPER1 ITSN1 SNX17 DTX3L TUBGCP4 RAB40A PLEKHM1 GJA1 CD1C ARRB2 NOX1 RAB40AL VPS35L ATG9A BAIAP3 SLC9A6

1.19e-03116713317GO:0005768
GeneOntologyCellularComponentendoplasmic reticulum membrane

COPZ1 GPER1 SLC27A6 ERO1A ATG2A ITPR2 GJA1 PLA2G4C TMEM208 MACO1 LRRC8B HSD3B2 ATG9A UBIAD1 SLC9A6 MAN1B1 SOAT1 DGAT1

1.42e-03129313318GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

COPZ1 GPER1 SLC27A6 ERO1A ATG2A ITPR2 GJA1 PLA2G4C TMEM208 MACO1 LRRC8B HSD3B2 ATG9A UBIAD1 SLC9A6 MAN1B1 SOAT1 DGAT1

1.49e-03129913318GO:0098827
GeneOntologyCellularComponentnon-motile cilium

NPHP1 MAP1B MYO7A KIAA1549 ALPK1 TTLL6

1.61e-031961336GO:0097730
GeneOntologyCellularComponentaxon

MYH10 MAP1B GPER1 ITSN1 GRIK1 BCR ITPR2 CYFIP1 GRK2 P2RX3 MACO1 KCNMA1 IGSF9 SLC9A6

1.64e-0389113314GO:0030424
GeneOntologyCellularComponentdistal axon

MYH10 MAP1B GPER1 ITSN1 GRIK1 CYFIP1 P2RX3 KCNMA1 SLC9A6

1.89e-034351339GO:0150034
GeneOntologyCellularComponentphotoreceptor cell cilium

NPHP1 MAP1B MYO7A KIAA1549 ALPK1

1.97e-031391335GO:0097733
GeneOntologyCellularComponentGolgi apparatus subcompartment

SLC11A2 GPER1 ST3GAL3 C17orf75 MGAT2 TMBIM4 ATG9A BAIAP3 COG4

2.14e-034431339GO:0098791
HumanPhenoHighly arched eyebrow

NPHP1 RPS6KA3 KAT6A BCR LRPPRC KMT2D VPS35L TMEM218 CPLANE1 MAN1B1

3.99e-052065310HP:0002553
HumanPhenoAbnormality of the chin

DOCK3 ERCC4 PTF1A RPS6KA3 KAT6A TUBGCP4 XRCC4 BCR TRIP12 GJA1 KMT2D MGAT2 SLC9A6 MAN1B1

4.85e-054095314HP:0000306
HumanPhenoLong face

NPHP1 DOCK3 ERCC4 KAT6A XRCC4 BCR TMEM218 CPLANE1 MAPRE2 SLC9A6 MAN1B1

5.38e-052595311HP:0000276
HumanPhenoAbnormal columella morphology

CHST14 RPS6KA3 KAT6A TRIP12 GJA1 KMT2D MGAT2

5.50e-0597537HP:0009929
DomainARM-type_fold

DOCK3 RALGAPA2 TRIP12 PAIP1 RSPRY1 ITPR2 RANBP17 RIF1 AOPEP PKP3 LTN1 XPO7

5.66e-0633913312IPR016024
DomainRibosomal_S6_kinase_II

RPS6KA1 RPS6KA3 RPS6KA6

6.95e-0661333IPR016239
DomainOat_ACAT_DAG_ARE

SOAT1 DGAT1

1.50e-0431332IPR014371
PathwayREACTOME_CREB1_PHOSPHORYLATION_THROUGH_NMDA_RECEPTOR_MEDIATED_ACTIVATION_OF_RAS_SIGNALING

RPS6KA1 RPS6KA3 RPS6KA6

3.13e-065973MM15108
PathwayKEGG_MEDICUS_REFERENCE_ERK_RSK_SIGNALING

RPS6KA1 RPS6KA3 RPS6KA6

6.22e-066973M47936
PathwayREACTOME_RSK_ACTIVATION

RPS6KA1 RPS6KA3 RPS6KA6

1.08e-057973M27369
PathwaySIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES

RPS6KA1 RPS6KA3 BCR ITPR2

1.05e-0436974M1315
PathwayREACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS

RPS6KA1 RPS6KA3 RPS6KA6

1.35e-0415973MM15103
Pubmed

The RSK2-RPS6 axis promotes axonal regeneration in the peripheral and central nervous systems.

RPS6KA1 RPS6KA3 RPS6KA6

5.69e-075135337068088
Pubmed

RSK2 is a modulator of craniofacial development.

RPS6KA1 RPS6KA3 RPS6KA6

5.69e-075135324416220
Pubmed

Cognitive impairment in Coffin-Lowry syndrome correlates with reduced RSK2 activation.

RPS6KA1 RPS6KA3 RPS6KA6

5.69e-075135311160957
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

ZWILCH ERCC4 FLYWCH1 ERO1A RPS6KA3 ITSN1 TRIP12 AOPEP VPS35L LTN1 HSD3B2 CPLANE1 BAIAP3 MFSD1 COG4 MAN1B1 RAD17

1.12e-0610841351711544199
Pubmed

Phosphorylation of p90 ribosomal S6 kinase (RSK) regulates extracellular signal-regulated kinase docking and RSK activity.

RPS6KA1 RPS6KA3 RPS6KA6

1.13e-066135312832467
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

MYH10 MAP1B KAT6A GRIK1 ST3GAL3 BCR NDUFB5 PLEKHM1 RANBP17 LRPPRC ARRB2 AOPEP PKP3 VPS35L RASGEF1C KCNMA1 IGSF9 BAIAP3 MAN1B1 XPO7

1.30e-0614891352028611215
Pubmed

SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity.

EPB41L5 NR4A3 PKD1L2 NDUFB5 ACOX3 PLA2G4C RNFT2 RASGEF1C TMEM218 EXOG DNAH6 BAIAP3 MFSD1 CEP19 NAA16

2.93e-069151351532393512
Pubmed

Nur77 is phosphorylated in cells by RSK in response to mitogenic stimulation.

RPS6KA1 RPS6KA3 NR4A3

3.16e-068135316223362
Pubmed

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.

MAP1B CHST14 TUBGCP4 RIF1 LRPPRC MACO1 LTN1 RARS2 ATG9A UBIAD1 SOAT1 XPO7

1.05e-056571351236180527
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

NPHP1 MYH10 FBXL13 MAP1B EPB41L5 RALGAPA2 SKP1 VPS13D LTN1 KCNMA1 CPLANE1

1.35e-055641351121565611
Pubmed

A novel GRK2 inhibitor alleviates experimental arthritis through restraining Th17 cell differentiation.

ARRB2 GRK2

1.50e-052135236399825
Pubmed

RSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells.

RPS6KA1 RPS6KA3

1.50e-052135219716794
Pubmed

The RSK family of kinases: emerging roles in cellular signalling.

RPS6KA1 RPS6KA3

1.50e-052135218813292
Pubmed

Peritoneal and hematogenous metastases of ovarian cancer cells are both controlled by the p90RSK through a self-reinforcing cell autonomous mechanism.

RPS6KA1 RPS6KA3

1.50e-052135226625210
Pubmed

End binding protein-1 (EB1) complements microtubule-associated protein-1B during axonogenesis.

MAP1B MAPRE2

1.50e-052135215789376
Pubmed

Astrocytic calcium release mediates peri-infarct depolarizations in a rodent stroke model.

ITPR2 GJA1

1.50e-052135227991861
Pubmed

S6 kinase inactivation impairs growth and translational target phosphorylation in muscle cells maintaining proper regulation of protein turnover.

RPS6KA1 RPS6KA3

1.50e-052135217494629
Pubmed

Quantitative analysis of autophagy reveals the role of ATG9 and ATG2 in autophagosome formation.

ATG2A ATG9A

1.50e-052135237115157
Pubmed

Competing G protein-coupled receptor kinases balance G protein and β-arrestin signaling.

ARRB2 GRK2

1.50e-052135222735336
Pubmed

Identification of a novel putative Ran-binding protein and its close homologue.

RANBP17 XPO7

1.50e-052135211071879
Pubmed

Two widely used RSK inhibitors, BI-D1870 and SL0101, alter mTORC1 signaling in a RSK-independent manner.

RPS6KA1 RPS6KA3

1.50e-052135225889895
Pubmed

Sequence and expression of chicken and mouse rsk: homologs of Xenopus laevis ribosomal S6 kinase.

RPS6KA1 RPS6KA3

1.50e-05213522779569
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

ERCC4 FLYWCH1 COPZ1 NR4A3 DTX3L NDUFB5 MTPAP RSPRY1 RIF1 MGAT2 CYFIP1 VPS35L UBIAD1 TOP2B SOAT1 XPO7

1.85e-0512031351629180619
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

SNX17 ATG2A PLEKHM1 ITPR2 VPS13D MACO1 VPS35L ATG9A COG4 SOAT1

2.93e-055041351034432599
Pubmed

SH3P2 is a negative regulator of cell motility whose function is inhibited by ribosomal S6 kinase-mediated phosphorylation.

RPS6KA1 RPS6KA3

4.48e-053135221501342
Pubmed

Characterization of two human genes encoding acyl coenzyme A:cholesterol acyltransferase-related enzymes.

SOAT1 DGAT1

4.48e-05313529756920
Pubmed

p90 ribosomal S6 kinase and p70 ribosomal S6 kinase link phosphorylation of the eukaryotic chaperonin containing TCP-1 to growth factor, insulin, and nutrient signaling.

RPS6KA1 RPS6KA3

4.48e-053135219332537
Pubmed

p90RSK Regulates p53 Pathway by MDM2 Phosphorylation in Thyroid Tumors.

RPS6KA1 RPS6KA3

4.48e-053135236612117
Pubmed

Y-box binding protein-1 serine 102 is a downstream target of p90 ribosomal S6 kinase in basal-like breast cancer cells.

RPS6KA1 RPS6KA3

4.48e-053135219036157
Pubmed

Deletion of ribosomal S6 kinases does not attenuate pathological, physiological, or insulin-like growth factor 1 receptor-phosphoinositide 3-kinase-induced cardiac hypertrophy.

RPS6KA1 RPS6KA3

4.48e-053135215226426
Pubmed

RNA editing induces variation in desensitization and trafficking of 5-hydroxytryptamine 2c receptor isoforms.

ARRB2 GRK2

4.48e-053135214602721
Pubmed

β-Arrestin 1 and 2 and G protein-coupled receptor kinase 2 expression in pituitary adenomas: role in the regulation of response to somatostatin analogue treatment in patients with acromegaly.

ARRB2 GRK2

4.48e-053135224169548
Pubmed

Expression analysis of RSK gene family members: the RSK2 gene, mutated in Coffin-Lowry syndrome, is prominently expressed in brain structures essential for cognitive function and learning.

RPS6KA1 RPS6KA3

4.48e-053135212393804
Pubmed

Identification of RANBP16 and RANBP17 as novel interaction partners for the bHLH transcription factor E12.

RANBP17 XPO7

4.48e-053135220503194
Pubmed

G protein-coupled receptor kinase 2, with β-arrestin 2, impairs insulin-induced Akt/endothelial nitric oxide synthase signaling in ob/ob mouse aorta.

ARRB2 GRK2

4.48e-053135222688330
Pubmed

Crucial roles of RSK in cell motility by catalysing serine phosphorylation of EphA2.

RPS6KA1 RPS6KA3

4.48e-053135226158630
Pubmed

The Clinical Implications of RSK1-3 in Human Breast Cancer.

RPS6KA1 RPS6KA3

4.48e-053135226977024
Pubmed

Diversity of Ca2+-activated K+ channel transcripts in inner ear hair cells.

SLC11A2 KCNMA1

4.48e-053135217097837
Pubmed

Regulation of Constitutive GPR3 Signaling and Surface Localization by GRK2 and β-arrestin-2 Overexpression in HEK293 Cells.

ARRB2 GRK2

4.48e-053135223826079
Pubmed

Beta-arrestin2 as a competitor for GRK2 interaction with the GLP-1 receptor upon receptor activation.

ARRB2 GRK2

4.48e-053135221952200
Pubmed

Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2.

ARRB2 GRK2

4.48e-053135215618519
Pubmed

Loss of striatal 90-kDa ribosomal S6 kinase (Rsk) is a key factor for motor, synaptic and transcription dysfunction in Huntington's disease.

RPS6KA1 RPS6KA3

4.48e-053135227063456
Pubmed

Mapping the transcriptional machinery of the IL-8 gene in human bronchial epithelial cells.

RPS6KA1 RPS6KA3

4.48e-053135222031759
Pubmed

Increased 90-kDa ribosomal S6 kinase (Rsk) activity is protective against mutant huntingtin toxicity.

RPS6KA1 RPS6KA3

4.48e-053135222041125
Pubmed

Vascular dysfunction in human and rat cirrhosis: role of receptor-desensitizing and calcium-sensitizing proteins.

ARRB2 GRK2

4.48e-053135217256744
Pubmed

Paraoxonase 2 (PON2) decreases high glucose-induced macrophage triglycerides (TG) accumulation, via inhibition of NADPH-oxidase and DGAT1 activity: studies in PON2-deficient mice.

NOX1 DGAT1

4.48e-053135219748094
Pubmed

Regulation of GPR54 signaling by GRK2 and {beta}-arrestin.

ARRB2 GRK2

4.48e-053135219846537
Pubmed

Connexin43 interacts with βarrestin: a pre-requisite for osteoblast survival induced by parathyroid hormone.

GJA1 ARRB2

4.48e-053135221630325
Pubmed

The Contribution of Mosaic Variants to Autism Spectrum Disorder.

MYH10 KMT2D

4.48e-053135227632392
Pubmed

Human rsk isoforms: cloning and characterization of tissue-specific expression.

RPS6KA1 RPS6KA3

4.48e-05313528141249
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

ZWILCH COPZ1 ARID4A ITSN1 EPB41L5 ST3GAL3 RIF1 PKP3 ATG9A MAPRE2 BAIAP3 MFSD1 EPB41L2

6.77e-059251351328986522
Pubmed

Comprehensive analysis of interactions between the Src-associated protein in mitosis of 68 kDa and the human Src-homology 3 proteome.

NPHP1 DOCK3 MYO7A ITSN1

6.82e-0556135422745667
Pubmed

Large-scale concatenation cDNA sequencing.

BTBD2 RALGAPA2 RIF1 LRPPRC VPS13D C17orf75 BAIAP3 SDK1 EPB41L2 XPR1

7.93e-05568135109110174
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

SLC11A2 SNX17 EPB41L5 KIAA1549 RALGAPA2 NOX1 NAV2 UBIAD1 EPB41L2 ARAP2

8.04e-055691351030639242
Pubmed

A "double adaptor" method for improved shotgun library construction.

BTBD2 RALGAPA2 RIF1 LRPPRC VPS13D C17orf75 BAIAP3 SDK1 EPB41L2 XPR1

8.64e-05574135108619474
Pubmed

Phosphatidylinositol-3-OH Kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K.

RPS6KA1 RPS6KA3

8.93e-054135211507039
Pubmed

The UBIAD1 prenyltransferase links menaquinone-4 [corrected] synthesis to cholesterol metabolic enzymes.

UBIAD1 SOAT1

8.93e-054135223169578
Pubmed

Gravin-mediated formation of signaling complexes in beta 2-adrenergic receptor desensitization and resensitization.

ARRB2 GRK2

8.93e-054135210858453
Pubmed

Overexpression of human diacylglycerol acyltransferase 1, acyl-coa:cholesterol acyltransferase 1, or acyl-CoA:cholesterol acyltransferase 2 stimulates secretion of apolipoprotein B-containing lipoproteins in McA-RH7777 cells.

SOAT1 DGAT1

8.93e-054135215308631
Pubmed

A model for a partnership of lipid transfer proteins and scramblases in membrane expansion and organelle biogenesis.

ATG2A ATG9A

8.93e-054135233850023
Pubmed

Rsk2 allosterically activates estrogen receptor alpha by docking to the hormone-binding domain.

RPS6KA1 RPS6KA3

8.93e-054135211432835
Pubmed

TOM40 Targets Atg2 to Mitochondria-Associated ER Membranes for Phagophore Expansion.

ATG2A ATG9A

8.93e-054135231412244
Pubmed

Alpha2A- and alpha2C-adrenergic receptors form homo- and heterodimers: the heterodimeric state impairs agonist-promoted GRK phosphorylation and beta-arrestin recruitment.

ARRB2 GRK2

8.93e-054135216605244
Pubmed

Manipulation of pro-inflammatory cytokine production by the bacterial cell-penetrating effector protein YopM is independent of its interaction with host cell kinases RSK1 and PRK2.

RPS6KA1 RPS6KA3

8.93e-054135225513777
Pubmed

VIIa/tissue factor interaction results in a tissue factor cytoplasmic domain-independent activation of protein synthesis, p70, and p90 S6 kinase phosphorylation.

RPS6KA1 F3

8.93e-054135212019261
Pubmed

Two distinct mechanisms mediate acute mu-opioid receptor desensitization in native neurons.

ARRB2 GRK2

8.93e-054135219279269
Pubmed

Rsk-2 activity is necessary for epidermal growth factor-induced phosphorylation of CREB protein and transcription of c-fos gene.

RPS6KA1 RPS6KA3

8.93e-05413529770464
Pubmed

Inhibition of G Protein-Coupled Receptor Kinase 2 Promotes Unbiased Downregulation of IGF1 Receptor and Restrains Malignant Cell Growth.

ARRB2 GRK2

8.93e-054135233158816
Pubmed

Multiple scaffolding functions of {beta}-arrestins in the degradation of G protein-coupled receptor kinase 2.

ARRB2 GRK2

8.93e-054135221081496
Pubmed

Distinct cellular and subcellular distributions of G protein-coupled receptor kinase and arrestin isoforms in the striatum.

ARRB2 GRK2

8.93e-054135223139825
Pubmed

Distinct cortical and striatal actions of a β-arrestin-biased dopamine D2 receptor ligand reveal unique antipsychotic-like properties.

ARRB2 GRK2

8.93e-054135227911814
Pubmed

G protein-coupled estrogen receptor 1/G protein-coupled receptor 30 localizes in the plasma membrane and traffics intracellularly on cytokeratin intermediate filaments.

GPER1 ARRB2

8.93e-054135221149639
Pubmed

Expression pattern of the Rsk2, Rsk4 and Pdk1 genes during murine embryogenesis.

RPS6KA3 RPS6KA6

8.93e-054135212711546
Pubmed

Tbx2 is a master regulator of inner versus outer hair cell differentiation.

MYO7A KCNMA1 ATP2B2

9.57e-0523135335508658
Pubmed

Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs.

PAIP1 ARRB2 ATG9A

1.09e-0424135337100772
Pubmed

Functional proteomics mapping of a human signaling pathway.

MYH10 ITSN1 SNX17 BTBD2 TRIP12 ACOX3 KMT2D ARRB2 MACO1 SDK1

1.10e-045911351015231748
Pubmed

A human MAP kinase interactome.

MYH10 ITSN1 RIF1 ARRB2 CEP95 NAV2 CPLANE1 COG4 EPB41L2

1.25e-04486135920936779
Pubmed

A directed protein interaction network for investigating intracellular signal transduction.

RPS6KA1 RPS6KA3 ITSN1 BTBD2 TUBGCP4 CHN1 PLEKHM1 GRK2 RPS6KA6 ATG9A QRSL1 COG4 MAN1B1 XPO7

1.27e-0411241351421900206
Pubmed

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.

ERO1A NCF2 ITPR2 MGAT2 RARS2 ATG9A COG4

1.31e-04285135732838362
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

MYH10 FLYWCH1 MAP1B ARID4A SNX17 SKP1 TRIP12 MTPAP RIF1 KMT2D TOP2B XPO7

1.35e-048571351225609649
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

MYH10 MAP1B MYO7A ITSN1 KIAA1549 BCR NDUFB5 ITPR2 GJA1 LRPPRC CYFIP1 GRK2 P2RX3 DNAH6 ATP2B2 EPB41L2

1.43e-0414311351637142655
Pubmed

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

MYO7A ERO1A GRIK1 SKP1 MTPAP CYFIP1 TTLL6 RASGEF1C CFAP70

1.45e-04496135931343991
Pubmed

90-kDa ribosomal S6 kinase is phosphorylated and activated by 3-phosphoinositide-dependent protein kinase-1.

RPS6KA1 RPS6KA3

1.48e-045135210480933
Pubmed

Ubiquitination of GRK2 Is Required for the β-Arrestin-Biased Signaling Pathway of Dopamine D2 Receptors to Activate ERK Kinases.

ARRB2 GRK2

1.48e-045135237373182
Pubmed

β-Arrestin2 directly or through GRK2 inhibits PKCβII activation in a ubiquitination-dependent manner.

ARRB2 GRK2

1.48e-045135229054428
Pubmed

The tRNA methylase METTL1 is phosphorylated and inactivated by PKB and RSK in vitro and in cells.

RPS6KA1 RPS6KA3

1.48e-045135215861136
Pubmed

Inhibitor of G protein-coupled receptor kinase 2 normalizes vascular endothelial function in type 2 diabetic mice by improving β-arrestin 2 translocation and ameliorating Akt/eNOS signal dysfunction.

ARRB2 GRK2

1.48e-045135222581458
Pubmed

The collapsin response mediator protein 1 (CRMP-1) and the promyelocytic leukemia zinc finger protein (PLZF) bind to UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE), the key enzyme of sialic acid biosynthesis.

KIAA1549 RIF1

1.48e-045135217118363
Pubmed

Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance.

RPS6KA1 RPS6KA3

1.48e-045135211139588
Pubmed

The PDK1-Rsk Signaling Pathway Controls Langerhans Cell Proliferation and Patterning.

RPS6KA1 RPS6KA3

1.48e-045135226401001
Pubmed

Ribosomal S6 kinase 2 interacts with and phosphorylates PDZ domain-containing proteins and regulates AMPA receptor transmission.

RPS6KA1 RPS6KA3

1.48e-045135216217014
Pubmed

Assessment of myosin II, Va, VI and VIIa loss of function on endocytosis and endocytic vesicle motility in bone marrow-derived dendritic cells.

MYH10 MYO7A

1.48e-045135217615572
Pubmed

Identification of an extracellular signal-regulated kinase (ERK) docking site in ribosomal S6 kinase, a sequence critical for activation by ERK in vivo.

RPS6KA1 RPS6KA3

1.48e-04513529915826
Pubmed

Systemic regulation of vascular NAD(P)H oxidase activity and nox isoform expression in human arteries and veins.

NCF2 NOX1

1.48e-045135215256399
Pubmed

Macrophage autophagy in immunity to Cryptococcus neoformans and Candida albicans.

ATG2A ATG9A

1.48e-045135222710871
Pubmed

Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated raptor phosphorylation.

RPS6KA1 RPS6KA3

1.48e-045135218722121
Pubmed

pp90rsk1 regulates estrogen receptor-mediated transcription through phosphorylation of Ser-167.

RPS6KA1 RPS6KA3

1.48e-04513529528769
Pubmed

Rab40b and Tks5 interact at invadopodia during metastasis.

RAB40A RAB40AL

1.48e-045135227909076
Pubmed

Anti-apoptotic actions of vasopressin in H32 neurons involve MAP kinase transactivation and Bad phosphorylation.

RPS6KA1 RPS6KA3

1.48e-045135218402937
Pubmed

The p53 protein is a novel substrate of ribosomal S6 kinase 2 and a critical intermediary for ribosomal S6 kinase 2 and histone H3 interaction.

RPS6KA1 RPS6KA3

1.48e-045135215867353
InteractionGPR182 interactions

ZWILCH TUBGCP4 MTPAP GJA1 RIF1 ARRB2 MACO1 LTN1 RARS2 EXOG ATP2B2 COG4 MAN1B1 SOAT1 DGAT1 XPR1 XPO7

6.75e-0945513117int:GPR182
InteractionVSIG1 interactions

TUBGCP4 EXOG SLC9A6 COG4 XPR1 XPO7

7.39e-06721316int:VSIG1
InteractionGPR17 interactions

ZWILCH TUBGCP4 ITPR2 GJA1 RIF1 GRK2 LTN1 COG4 DGAT1 XPO7

1.65e-0528313110int:GPR17
InteractionLAMP3 interactions

SLC11A2 EPB41L5 RALGAPA2 MTPAP ITPR2 GJA1 RIF1 MACO1 LTN1 UBIAD1 SLC26A11 SOAT1 XPR1

1.74e-0548613113int:LAMP3
InteractionTTYH1 interactions

SLC27A6 NDUFB5 GJA1 KCNT2 MACO1 LRRC8B ATP2B2 SOAT1 DGAT1 XPR1

2.71e-0530013110int:TTYH1
InteractionTMEM38A interactions

DOK2 ARRB2 HSD3B2

4.26e-05111313int:TMEM38A
InteractionPTPN3 interactions

RPS6KA1 RPS6KA3 EPB41L5 BCR LRPPRC XPR1

4.86e-051001316int:PTPN3
GeneFamilyMitogen-activated protein kinase-activated protein kinases

RPS6KA1 RPS6KA3 RPS6KA6

1.73e-05118731156
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ITSN1 BCR BAIAP3

6.85e-0436873823
CoexpressionGSE11924_TFH_VS_TH17_CD4_TCELL_UP

ARID4A BTBD2 TUBGCP4 RSPRY1 KMT2D CEP95 SLC26A11 MAPRE2 COG4 MAN1B1

7.62e-0819913310M3156
CoexpressionGSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_16H_UP

FLYWCH1 RPS6KA1 AOPEP PKP3 INTS15 IGSF9 ARAP2 SLC66A3

8.66e-062001338M8258
CoexpressionCREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_2

NPHP1 MYH10 ERCC4 FBXL13 KIAA1549 KIF24 TTLL6 CFAP70 CPLANE1 DNAH6 CEP19

2.96e-0547113311M3062
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

SLC11A2 MAP1B ARID4A RPS6KA3 ITSN1 KAT6A XRCC4 F3 TRIP12 PAIP1 GJA1 RIF1 LRPPRC LTN1 ARAP2

3.07e-0585613315M4500
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FBXL13 CFAP54 TTLL6 CFAP70 DNAH6 BAIAP3 SDK1

1.20e-0617913475e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC11A2 MYO7A ITPR2 CYFIP1 ARRB2 KCNMA1 MFSD1

2.06e-061941347663e7e7fe48157e808b4f1a0ea6ad41944e857a2
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK3 NCF2 CYFIP1 KCNMA1 SLC26A11 MFSD1 SOAT1

2.35e-0619813470b41b3d6c2db795320e8b65d40d85fb8b618cc34
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NPHP1 FBXL13 KIF24 CFAP54 CFAP70 DNAH6

8.15e-061571346410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LVRN RPS6KA1 NOX1 PKP3 IGSF9 DGAT1

9.08e-0616013468308ca6f37986c526432a0fbc5f7ec2e75cfb6d7
ToppCell367C-Epithelial_cells-Epithelial-I_(AT1)-|367C / Donor, Lineage, Cell class and subclass (all cells)

EPB41L5 RANBP17 RNFT2 RAB40AL IGSF9 PLD5

1.46e-051741346edf839d79ac58921f4e788f3b2cb2ae0d6af4b9e
ToppCell367C-Epithelial_cells-Epithelial-I_(AT1)|367C / Donor, Lineage, Cell class and subclass (all cells)

EPB41L5 RANBP17 RNFT2 RAB40AL IGSF9 PLD5

1.46e-05174134665539f69100db0b7d90b1b39ee15ab8281f86461
ToppCellmetastatic_Brain-Endothelial_cells-Lymphatic_ECs|Endothelial_cells / Location, Cell class and cell subclass

BTBD2 F3 RSPRY1 ARRB2 AOPEP PKP3

1.56e-05176134642541dfe20eb29625d47c0bb79bf3c21a2460340
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 FBXL13 RNFT2 CFAP70 DNAH6 BAIAP3

1.77e-0518013461f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCellCOVID-19-Epithelial-Ionocytes|Epithelial / Condition, Lineage and Cell class

DOCK3 TRAV3 GPER1 GRIK1 ITPR2 KCNMA1

1.83e-0518113464a8d4f2709c1b25f908867f1b2fae1d2d0abf1d4
ToppCellCOPD-Epithelial-ATI|World / Disease state, Lineage and Cell class

EPB41L5 F3 RANBP17 GJA1 KCNT2 NAV2

1.89e-051821346e95d946a43b1579af199900bb0e3eacbb9d65300
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

MYH10 MAP1B GPER1 CHN1 GJA1 KCNMA1

2.07e-051851346427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D175|Adult / Lineage, Cell type, age group and donor

EPB41L5 F3 RANBP17 KCNT2 CPLANE1 ARAP2

2.07e-05185134632b4e68e551d435a732f253f6ad83408c759a642
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NPHP1 CFAP54 ANKRD18A CFAP70 DNAH6 BAIAP3

2.13e-05186134676033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellCOPD-Epithelial-ATI|COPD / Disease state, Lineage and Cell class

EPB41L5 F3 RANBP17 GJA1 KCNT2 NAV2

2.13e-051861346df0977f6f48a2d4e11b59971f098b01204242f0f
ToppCellCOVID-19-kidney-Fibroblast-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYH10 MAP1B SLC27A6 NR4A3 NAV2 SDK1

2.20e-05187134676bfe8c42430a230a8bdf299575c444fb7780f24
ToppCellCiliated_cells-B-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

MAP1B CFAP54 ANKRD18A CFAP70 DNAH6 BAIAP3

2.20e-0518713466fa38dbccca36bc7a4fef46de74c6688f599f421
ToppCellEpithelial-Epithelial-D_(Ciliated)|Epithelial / shred on cell class and cell subclass (v4)

NPHP1 MAP1B CFAP54 TTLL6 CFAP70 DNAH6

2.26e-0518813468f30535a32968a81a304315a49c0d90a77d36948
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

MYH10 KCNT2 KCNMA1 RPS6KA6 PLD5 SDK1

2.33e-0518913466b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellAT1_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

ARID4A EPB41L5 RANBP17 GJA1 KCNT2 ARAP2

2.55e-0519213460444f9e9cef7403e220e862b5a787443d3f5c9ac
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SKP1 F3 GJA1 AOPEP SDK1 EPB41L2

2.70e-051941346735eee6ef25589f935fa922788ebbdbfef61249e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 MAP1B PLA2G4C KCNT2 PLD5 EPB41L2

2.70e-05194134690efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 MAP1B PLA2G4C KCNT2 PLD5 EPB41L2

2.70e-051941346df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCellIIH-mono3-|IIH / Condition, Cell_class and T cell subcluster

OTOA NR4A3 CYFIP1 RASGEF1C KCNMA1 EPB41L2

2.78e-05195134628a858b04a7b413916c07a8d880f5ea02e985461
ToppCellCOVID-19-Myeloid-Monocyte-derived_macrophages|COVID-19 / group, cell type (main and fine annotations)

ITSN1 NCF2 ITPR2 ARRB2 KCNMA1 MFSD1

2.78e-051951346c172c5599379c29123340621a36bfb1fc90c2115
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC11A2 CYFIP1 KCNMA1 SLC26A11 MFSD1 SOAT1

2.78e-0519513469d649ac7d2af313481069c95349efc0c68449e2b
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

OTOA ARRB2 TMBIM4 KCNMA1 MFSD1 SOAT1

2.78e-0519513469a9e074f7ac04656dccbed2f0df11377e33d3c05
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 RNFT2 CFAP70 CPLANE1 DNAH6 BAIAP3

2.78e-05195134679dc031258579ea328181dda33710dd897f1064a
ToppCellMacrophages-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

OTOA ARRB2 KCNMA1 SLC26A11 MFSD1 SOAT1

2.78e-051951346eb104f3bb08ab9eca31273c0523a5c90de1f30a9
ToppCellIIH-mono3|IIH / Condition, Cell_class and T cell subcluster

OTOA NR4A3 CYFIP1 RASGEF1C KCNMA1 EPB41L2

2.78e-051951346c6dd5af582d257be64b718e30f60220c1bf1738a
ToppCellCOVID-19-lung-Macrophage_metabolically_active|lung / Disease (COVID-19 only), tissue and cell type

SLC27A6 MYO7A NCF2 ARRB2 KCNMA1 MFSD1

2.86e-051961346a753d76d764c181eecb0e17a794a2e7d0ff70136
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 CFAP54 TTLL6 CFAP70 CPLANE1 DNAH6

2.94e-05197134674a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Dendritic_cell / Region, Cell class and subclass

ITSN1 RALGAPA2 BCR AOPEP BAIAP3 CEP19

2.94e-0519713468545baf923ddf84c5ce9414a36d810603be52401
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CYFIP1 ARRB2 TMBIM4 KCNMA1 MFSD1 SOAT1

2.94e-05197134650f994e0d4e69019ec92e164edf3e4e951333766
ToppCellTransplant_Alveoli_and_parenchyma-Immune-Luminal_Macrophages|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

OTOA NCF2 DOK2 KCNMA1 MFSD1 SOAT1

2.94e-051971346523a7f363c7ba8c196ea6e4f7544c29c18c10b51
ToppCellLPS_only-Epithelial_airway-airway_epithelial-Ciliated|LPS_only / Treatment groups by lineage, cell group, cell type

NPHP1 FBXL13 MYO7A CFAP54 CFAP70 DNAH6

3.03e-0519813466d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_macrophage|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

OTOA MYO7A ITSN1 CYFIP1 KCNMA1 MFSD1

3.11e-051991346b827dd8a249f904a0ff930a6c4d3b00fb7bc6fb1
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_macrophage-macrophage|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

OTOA MYO7A ITSN1 CYFIP1 KCNMA1 MFSD1

3.11e-051991346c0dcdda30485bb920d3706dcfb06f11b76b6ea37
ToppCellwk_15-18-Hematologic-Myeloid-SPP1+_Mac|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MYO7A NCF2 ITPR2 CYFIP1 ARRB2 MFSD1

3.11e-051991346c7fc2ac1601346aac71e7620a8a440fde8d92dbd
ToppCellParenchymal-10x5prime-Immune_Myeloid-Macrophage_other-Macro_CHIT1|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

OTOA NCF2 KCNMA1 SLC26A11 MFSD1 SOAT1

3.11e-051991346f987f48970aec46156b80656e49b9f3604f3758c
ToppCellHematolymphoid-Microglia-TYROBP----L1-3|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

ITPR2 CYFIP1 ARRB2 RASGEF1C KCNMA1 EPB41L2

3.20e-052001346a20dce14f94777687aad57d6fbe3258ad376f63f
ToppCellHematolymphoid-Microglia-TYROBP--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

ITPR2 CYFIP1 ARRB2 RASGEF1C KCNMA1 EPB41L2

3.20e-052001346dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCellHematolymphoid-Microglia-TYROBP-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

ITPR2 CYFIP1 ARRB2 RASGEF1C KCNMA1 EPB41L2

3.20e-0520013463bba5219453322198e8fdb0921d5f8c403598751
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

OTOA MYO7A NCF2 ITPR2 KCNMA1 MFSD1

3.20e-0520013464b4df0fe47498310d94448b8a289e58e4f5b5aa8
ToppCellHematolymphoid-Microglia|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

ITPR2 CYFIP1 ARRB2 RASGEF1C KCNMA1 EPB41L2

3.20e-05200134621bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCellHematolymphoid-Microglia-TYROBP---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

ITPR2 CYFIP1 ARRB2 RASGEF1C KCNMA1 EPB41L2

3.20e-052001346a8646d0fca99f10827c2d2a12e584660ef7155f1
ToppCellHematolymphoid-Microglia-TYROBP|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

ITPR2 CYFIP1 ARRB2 RASGEF1C KCNMA1 EPB41L2

3.20e-05200134633036d21c1c82109284473a515c4f890b33fdd5c
ToppCell10x5'v1-week_14-16-Myeloid_macrophage-stroma-stromal_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

OTOA MYO7A NR4A3 CYFIP1 KCNMA1 MFSD1

3.20e-052001346af743dfef7e7cfaef1c494999757123f93a213e3
ToppCell367C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

RNFT2 RAB40AL IGSF9 PLD5

3.22e-0560134428415d543aaccc74d19e1bb92b7e6fa94f97f8f2
ToppCell367C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

RNFT2 RAB40AL IGSF9 PLD5

3.22e-0560134471eba0fbef11cfc2b1c525d5f051530750e4fce9
ToppCellTCGA-Mesothelium-Primary_Tumor-Mesothelioma-Epitheliod-3|TCGA-Mesothelium / Sample_Type by Project: Shred V9

NPHP1 KIAA1549 GJA1 KCNT2 RNFT2

5.93e-051371345a1e34ebbeda3d5a4f14917282d44fcb4dcbf3133
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-CR|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GPER1 SLC27A6 PKP3 IGSF9

1.15e-048313441ab68323518adc7fd0a459b41fad12d60f97eb5c
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-CR-CR_Lhx5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GPER1 SLC27A6 PKP3 IGSF9

1.15e-0483134475b27d91a4473286f4b40027e96ac5246f5abe5b
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LVRN ZWILCH NOX1 PKP3 IGSF9

1.38e-041641345e5258efd6765acfc394708f697ec76acaef09079
ToppCellNS-critical-d_0-4-Myeloid-Resident_Macrophage|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NR4A3 ZKSCAN2 CHN1 CD1C EPB41L2

1.42e-0416513456b1c29dcef5a945786806ddbddddcec0023bd66e
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7-Slc17a8.Syt6-Lancl3_(Cortical_Subplate_pyramidal_cells)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

DOK2 PKD1L2 NOX1 CFAP70

1.45e-04881344fcc15c5c30517c63a835b28627c5f779d9bcd17e
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7-Slc17a8.Syt6-Lancl3_(Cortical_Subplate_pyramidal_cells)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

DOK2 PKD1L2 NOX1 CFAP70

1.45e-048813447838c65160cf81c02b923fc34f566c0610c8d81b
ToppCellfacs-Heart-LA-18m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S PKD1L2 GRK2 TTLL6 PKP3

1.51e-0416713458ce8d93c79ac6a3f52252b4cec53378c362bfe0a
ToppCellfacs-Heart-LA-18m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S PKD1L2 GRK2 TTLL6 PKP3

1.51e-0416713458340f7075d00dccb304cfd4c9b5711ca6dbf7cce
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B KCNT2 TMBIM4 PLD5 EPB41L2

1.55e-041681345d19a115365c5415e51c039718d7669de788fcf33
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 CFAP54 CFAP70 CPLANE1 DNAH6

1.59e-041691345fba841664939c771881ba97f14ef1df6635c04ff
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP54 ANKRD18A CFAP70 DNAH6 BAIAP3

1.59e-04169134514aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR4A3 PLA2G4C PLD5 DNAH6 ATP2B2

1.59e-04169134512bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 CFAP70 CPLANE1 DNAH6 BAIAP3

1.68e-0417113451854a777d9eb9d3fc3ed3632332a6f89ce8131da
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO7A BCR RANBP17 GJA1 CEP19

1.73e-041721345b3c4adccc34bb9e4e78e40f4e2e23736c347cc75
ToppCellNasal_Brush-Epithelial-Ionocytes|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

ST3GAL3 XRCC4 ITPR2 PLA2G4C KCNMA1

1.73e-04172134504fabb40fa9357d8902f3b04adc15231626cd9f8
ToppCellNasal_Brush-Epithelial-Ionocytes|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

ST3GAL3 XRCC4 ITPR2 PLA2G4C KCNMA1

1.73e-041721345dd3a23dc78dc6939f41126f8d7bd23a2e4713647
ToppCellfacs-Lung-Endomucin-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO7A BCR RANBP17 GJA1 CEP19

1.73e-0417213452f1673fcb2356684d60871debb0f159aec553a1c
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYH10 MAP1B GJA1 PLA2G4C VPS35L

1.73e-0417213451bad7b19724e1b53ace7e05644215334c9f43910
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

FLYWCH1 MAP1B ZBTB8B GRIK1 LHFPL5

1.77e-0417313457e3897868dd3f6e4974f593c60649a543ffc8693
ToppCellControl-Epithelial_cells-AT1|Control / group, cell type (main and fine annotations)

EPB41L5 RANBP17 KCNT2 NAV2 ARAP2

1.82e-041741345548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCellfacs-Trachea-nan-18m-Lymphocytic-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOK2 PKP3 BAIAP3 DGAT1 ARAP2

1.92e-04176134514c6c3fdb53f9dfc02b951bc955b90213110c089
ToppCellfacs-GAT-Fat-24m-Lymphocytic-T_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST3GAL3 SLITRK1 PKP3 DGAT1 ARAP2

1.92e-0417613458caec727acae325a89a560ec44c933a635da496b
ToppCellfacs-Trachea-nan-18m-Lymphocytic|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOK2 PKP3 BAIAP3 DGAT1 ARAP2

1.92e-0417613459dd862dcee6947a53189728f6b4cd40e7b67cb71
ToppCellfacs-Trachea-nan-18m-Lymphocytic-T_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOK2 PKP3 BAIAP3 DGAT1 ARAP2

1.92e-041761345d990e7af8120210100d13caa0465b27cf77a451a
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S MYO7A ALPK1 CFAP54 TTLL6

1.97e-041771345e8bb4f8ecd5e283efec966b9fc2040a6152d5551
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B ITSN1 NAV2 PLD5 EPB41L2

2.03e-041781345d4ecb84e9b1f4ec49c519321156aa10f9bd34cce
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

EPB41L5 RANBP17 KCNT2 NAV2 ARAP2

2.08e-0417913454f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCellfacs-Trachea-18m-Hematologic-lymphocytic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DOK2 PKP3 BAIAP3 DGAT1 ARAP2

2.13e-041801345c35cf2510183c09688453b12e721d264cf57caad
ToppCellfacs-Trachea-18m-Hematologic-lymphocytic-T_cell-T_cell_of_trachea|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DOK2 PKP3 BAIAP3 DGAT1 ARAP2

2.19e-041811345a23b2e12bc133166e3ed45ab7116f74afbca6eec
ToppCellfacs-Trachea-18m-Hematologic-lymphocytic-T_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DOK2 PKP3 BAIAP3 DGAT1 ARAP2

2.19e-0418113457875fe64ec500a925245ab50cffd6890eabaea8c
ToppCell10x5'-bone_marrow-Mast-Mast_cell_lympho|bone_marrow / Manually curated celltypes from each tissue

NR4A3 ALPK1 MTPAP CFAP54 RARS2

2.19e-04181134556fa77ae31f3b7de6e441a439c33a11353b6573a
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S FBXL13 CFAP54 TTLL6 CFAP70

2.25e-041821345587636c0f127231de21acd8aa632b74ff22ca8c2
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S FBXL13 CFAP54 TTLL6 CFAP70

2.25e-041821345adfadd7893e74b3002f13f00875e3667d3493e0c
ToppCellGlobus_pallidus-Neuronal-Inhibitory|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

FLYWCH1 MAP1B ZBTB8B GRIK1 LHFPL5

2.25e-04182134504ccfa951eaa31fed6d140edb6c702d49363c5fa
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

MAP1B KIAA1549 GJA1 RPS6KA6 PLD5

2.25e-041821345ad4d74d8b19976e1ccc3c5ba8013199338cf6fd8
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MAP1B GPER1 KIAA1549 CFAP70 ATP2B2

2.30e-0418313456f8f997ffc9eaebca2683de125b6069d07c07d26
ToppCellIPF-Epithelial-ATI|World / Disease state, Lineage and Cell class

EPB41L5 RANBP17 GJA1 KCNT2 NAV2

2.30e-04183134531fef35ecf30162662f24d335d8f0cceacc07039
ToppCellIPF-Epithelial-ATI|IPF / Disease state, Lineage and Cell class

EPB41L5 F3 RANBP17 GJA1 KCNT2

2.30e-041831345c0a3541c45bd0c587603521f392f42dd86c3c35b
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

EPB41L5 RANBP17 KCNT2 NAV2 ARAP2

2.36e-04184134557c792e6e2fedba25d3350ffe649fd74750b579d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B KCNT2 NAV2 PLD5 EPB41L2

2.36e-041841345e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

EPB41L5 RANBP17 KCNT2 NAV2 ARAP2

2.36e-041841345d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

EPB41L5 RANBP17 KCNT2 NAV2 ARAP2

2.42e-0418513451c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellControl-Epithelial-ATI|World / Disease state, Lineage and Cell class

EPB41L5 F3 RANBP17 GJA1 PKP3

2.42e-0418513450563d5042bb96ecce8446fbf26d05ef7a45e23c5
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MAP1B CFAP54 CFAP70 DNAH6 BAIAP3

2.42e-0418513455e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell3'-Child09-12-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYH10 MAP1B MYO7A GJA1 VPS35L

2.42e-0418513459de1db2ce9e44956b1214daf6e1e161334679c88
ToppCellCV-Healthy-7|Healthy / Virus stimulation, Condition and Cluster

ZWILCH NR4A3 TUBGCP4 MAN1B1 XPR1

2.42e-0418513451979d189c204f4c2893e3170a514ee7d5523406c
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

FBXL13 CFAP54 CFAP70 DNAH6 BAIAP3

2.42e-04185134530f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell3'-Child09-12-SmallIntestine-Endothelial-lymphatic_endothelial|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYH10 MAP1B MYO7A GJA1 VPS35L

2.42e-04185134518f5d9438c76e37988a7d17aa2a080af6bedbfc4
ToppCelldroplet-Tongue-nan-24m-Epithelial-suprabasal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F3 GJA1 PKP3 EPB41L2 ARAP2

2.48e-0418613452913b5fd0617d024d600ba7015ec7b1961dade83
DrugAD 288

RPS6KA1 RPS6KA3 RPS6KA6 TOP2B

1.06e-06141334CID000073553
DiseaseCoffin-Lowry syndrome (implicated_via_orthology)

RPS6KA1 RPS6KA3 RPS6KA6

3.49e-0741323DOID:3783 (implicated_via_orthology)
Diseasevision disorder

MYH10 F3 SDK1

4.70e-05161323MONDO_0021084
DiseaseHereditary hearing loss and deafness

OTOA MYO7A LRPPRC LHFPL5 HARS1 ATP2B2

5.19e-051461326cv:C0236038
DiseaseNonsyndromic Hearing Loss and Deafness, Autosomal Recessive

OTOA MYO7A LHFPL5 ATP2B2

8.12e-05511324cv:CN043650
DiseaseFANCONI ANEMIA, COMPLEMENTATION GROUP Q

ERCC4 XRCC4

1.18e-0441322C3808988
DiseaseUsher Syndrome

MYO7A HARS1

1.18e-0441322C0271097
Diseasestathmin-2 measurement

COPZ1 ATG9A

2.94e-0461322EFO_0802087
DiseaseNonsyndromic genetic hearing loss

OTOA MYO7A LHFPL5 ATP2B2

3.83e-04761324cv:C5680182
DiseaseUsher syndrome

MYO7A HARS1

4.11e-0471322cv:C0271097
DiseaseUsher Syndrome, Type III

MYO7A HARS1

4.11e-0471322C1568248
Diseasealcohol consumption measurement

MYH10 ERCC4 ARID4A SNX17 ALPK1 RANBP17 LRPPRC PLA2G4C TTLL6 EXOG UBIAD1 MAPRE2 SDK1 ARAP2 XPO7

4.55e-04124213215EFO_0007878
DiseaseNonsyndromic Deafness

OTOA MYO7A GJA1 LHFPL5

4.88e-04811324C3711374
Diseasehypertension (biomarker_via_orthology)

NCF2 F3 GJA1 ARRB2 GRK2 HSD3B2

5.67e-042271326DOID:10763 (biomarker_via_orthology)
DiseasePITUITARY DWARFISM I

ERCC4 XRCC4

7.00e-0491322C0342573
Diseasebeta-defensin 1 measurement

LVRN CPN2

8.73e-04101322EFO_0801415
Diseaselow density lipoprotein cholesterol measurement, alcohol consumption measurement

TDRD15 SNX17 MACO1 MAPRE2

1.04e-03991324EFO_0004611, EFO_0007878
Diseaseautosomal dominant nonsyndromic deafness (is_implicated_in)

MAP1B ATP2B2

1.06e-03111322DOID:0050564 (is_implicated_in)
Diseaselow density lipoprotein cholesterol measurement, alcohol drinking

TDRD15 SNX17 MACO1 MAPRE2

1.16e-031021324EFO_0004329, EFO_0004611
Diseaseacute myeloid leukemia (implicated_via_orthology)

ARID4A TOP2B

1.27e-03121322DOID:9119 (implicated_via_orthology)
Diseaseamyotrophic lateral sclerosis, age at onset

ST3GAL3 ARAP2

2.01e-03151322EFO_0004847, MONDO_0004976
Diseaseresponse to statin, LDL cholesterol change measurement

TDRD15 EPB41L2

2.01e-03151322EFO_0007804, GO_0036273
Diseasetriacylglycerol 50:5 measurement

SNX17 PLD5

2.29e-03161322EFO_0010412
Diseasecardiac troponin T measurement

CACNA1S GRIK1 PKD1L2 XRCC4 SDK1

3.10e-032191325EFO_0005043
DiseaseBrugada syndrome

EXOG MAPRE2

3.23e-03191322MONDO_0015263
Diseaselow density lipoprotein cholesterol measurement, physical activity

TDRD15 MACO1 MAPRE2

3.26e-03661323EFO_0003940, EFO_0004611
DiseaseFamilial aplasia of the vermis

NPHP1 CPLANE1

3.58e-03201322cv:C0431399
Diseaseportal hypertension (biomarker_via_orthology)

ARRB2 GRK2

4.33e-03221322DOID:10762 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
NLNYILSKEFGLRLD

HSD3B2

266

P26439
LFAYKLLDRAIGGIN

CFAP54

726

Q96N23
YLFLRNIFVTSDIKI

CFAP54

1086

Q96N23
GIFRDLEELVKLYLG

CPN2

331

P22792
LGYKDLNLFKLFRLV

ARID4A

336

P29374
FRKLFELISLLNYTA

ANKRD18A

676

Q8IVF6
ENEIYLGSILLKFAR

CATSPERE

356

Q5SY80
SLRQLEKLFSFLRGY

CEP19

66

Q96LK0
GADLSLEKYRELNFL

ACOX3

66

O15254
GLFELYLTLADLQRF

BAIAP3

661

O94812
VNAIAGTLKLYFREL

BCR

1121

P11274
GLQFDKELRSLIAYL

COG4

701

Q9H9E3
DLLKELSNILGFIYD

GRIK1

481

P39086
FVLRDGFLFLYKDVK

ARAP2

1461

Q8WZ64
FLLRFLAKRLGDETY

AOPEP

591

Q8N6M6
LVKEDLREGLFLNVY

LVRN

211

Q6Q4G3
ARLFLENLIKYGILV

DGAT1

101

O75907
VLGLSFRKDLFIATY

ARRB2

71

P32121
YQLALIFTLLFVGEK

ATP2B2

961

Q01814
TFLLRFILDDSALYL

ATG2A

1151

Q2TAZ0
RFLYGLDVSGKLLQV

ALPK1

116

Q96QP1
EKIFSQKLGYLLFRD

GRK2

56

P25098
LGLILLNEKYFSELR

RANBP17

1006

Q9H2T7
YDFLLKFLLVGDRDV

RAB40A

11

Q8WXH6
YDFLLKFLLVGDRDV

RAB40AL

11

P0C0E4
DVSLFLFRALGKILY

RAD17

391

O75943
VYLFSIIGFLFLKDD

ITPR2

2406

Q14571
TEKNLYGRLGLILFD

INTS15

306

Q96N11
LLRNLSVVEFSFYLG

KIAA1549

1131

Q9HCM3
KDFGFLVDILYSALR

LTN1

676

O94822
ELGKVGFLNYRLFLT

NOX1

461

Q9Y5S8
KELGRSQALFLYELL

OTOA

551

Q7RTW8
EYRKLFDLALQGLQL

CYFIP1

386

Q7L576
TSAFFLETKERLYLL

DOK2

81

O60496
LNLYLLFGFTLLEAL

TMBIM4

96

Q9HC24
RFLDSKFYLLVVVGE

MAP1B

31

P46821
LLYFGLRFIAANDKL

KCNMA1

226

Q12791
ILGLQFKLFACEVLY

NCF2

111

P19878
KILRDYAGLILFLEE

MGAT2

246

Q10469
FGGRLLVLESFLYKQ

FLYWCH1

121

Q4VC44
AFQTEGKLYLILDFL

RPS6KA3

136

P51812
ILSFLAFVLGYRQDK

LHFPL5

191

Q8TAF8
LNLLEKDYFGLLFQE

EPB41L2

251

O43491
VLLADFVLEFRFEYL

MACO1

41

Q8N5G2
LLAFEIYFRKGKFLL

NAA16

676

Q6N069
ILILDNDGDRLFAKY

COPZ1

16

P61923
GLYALAAKDIFRQLE

KIF24

331

Q5T7B8
FGLAYLFRKVIEEQL

LRPPRC

1216

P42704
ILDSRGYLFLEVFFI

MFSD1

411

Q9H3U5
FLFLDKYGLRKLEAF

SLC11A2

196

P49281
IIKDFYLLGRGELFQ

TUBGCP4

356

Q9UGJ1
LLDFQEFTLYLSTRK

EXOG

301

Q9Y2C4
AFQTEGKLYLILDFL

RPS6KA6

141

Q9UK32
ERIGKKLNLFDSLYF

KCNT2

221

Q6UVM3
TLELLLKEFFEYFGN

MTPAP

436

Q9NVV4
ELDSILFLFEKILQF

RALGAPA2

81

Q2PPJ7
GLELFRLELDKYIQG

C17orf75

161

Q9HAS0
LEGFQDLKNLRTLYL

LRRC8B

531

Q6P9F7
LGETLKYLFLLFSDD

MAN1B1

661

Q9UKM7
VLFLGELYLNLEIKG

PAIP1

271

Q9H074
EQKAFALIREILAYL

PKD1L2

1941

Q7Z442
KVDTLRLAIGYINFL

PTF1A

201

Q7RTS3
GELQLLLFALFLSLY

OR10Z1

21

Q8NGY1
FLIDFSYLLSKREGQ

KAT6A

661

Q92794
EYIFDQLRNLTLKGL

PLA2G4C

251

Q9UP65
RYLFVLQLKQDILSG

EPB41L5

136

Q9HCM4
LLGDSNFLKRLLEYD

DNAH6

2831

Q9C0G6
SLVFIINLLRDIKYF

DOCK3

666

Q8IZD9
LSDLELLFRFYLFGL

CD1C

81

P29017
IKFLDLFLSYILERD

CPLANE1

1551

Q9H799
LLYRAFDQKLIFTVG

DTX3L

676

Q8TDB6
RILSGNFFLLKENYE

QRSL1

376

Q9H0R6
SLNLGLEKLEYFFLI

CACNA1S

81

Q13698
FIFLRLGLIYLEEKE

CFAP70

1001

Q5T0N1
VFFTRGLKYNFELIL

ATG9A

241

Q7Z3C6
KELYGFLFNDFLLLT

ITSN1

1476

Q15811
LALNIIELFYVFFKG

GJA1

221

P17302
FAVIENLKYLLFTRD

C1GALT1C1L

146

P0DN25
SIKNLLEIFDGLLEY

CEP95

96

Q96GE4
RAILQIFFYLSLKDV

FBXL13

161

Q8NEE6
LFPRLQKLLESDYFR

ERO1A

61

Q96HE7
DFYFGKLREIELLCQ

MAPRE2

266

Q15555
INIITGALKLYFRDL

CHN1

336

P15882
FLALLKFLYSDEVQI

BTBD2

171

Q9BX70
QSALLAGLRKFVLYE

SDK1

1336

Q7Z5N4
AGLRKFVLYELQVLA

SDK1

1341

Q7Z5N4
DLKLLFEYLTLFGID

HARS1

301

P12081
KSDLLLEGFNNYRFL

MYH10

296

P35580
LIFYRQILGDVLLKD

NPHP1

581

O15259
TLLKAFGIRFDVLVY

P2RX3

296

P56373
LGLQRIFYLKLEDLV

NR4A3

596

Q92570
KFYLVIEELSQLFRS

RNFT2

296

Q96EX2
LKFATRENGFLLQYL

PLEKHM1

801

Q9Y4G2
ALIIQDFKGLLLSDY

RARS2

431

Q5T160
RLVLEFSLLSYAFGK

SOAT1

166

P35610
SLDNLFLKEGRQLTY

RSPRY1

296

Q96DX4
KLREFQLLETGLFFL

SLC9A6

321

Q92581
VQDILKEFFDLRLSY

TOP2B

1036

Q02880
LDLQRIFALYSSLKF

PLD5

261

Q8N7P1
LFADLEINILFLKYL

TDRD15

1656

B5MCY1
GFSNLLFVDRIIYII

RIF1

746

Q5UIP0
FLGETFRDKLRLYIE

GPER1

326

Q99527
NLKAILGLFFSLSRY

NAV2

176

Q8IVL1
EYDRLGFLLNLDSKL

ST3GAL3

56

Q11203
AIFIKLALGLDLYLA

SLC5A4

166

Q9NY91
FVSLDRLLLEFVFQY

SIX6OS1

6

Q8N1H7
YFKFLFVREPLERLL

CHST14

206

Q8NCH0
ARDLLYFDGLRKLIF

PKP3

736

Q9Y446
IYRGGFLLIEFLFLL

XPR1

271

Q9UBH6
LIGYFSLFLVREKED

SNX17

156

Q15036
YRELKFLLVLADGLR

ZWILCH

266

Q9H900
DILDTFGKLVYERIF

VPS35L

236

Q7Z3J2
FRKQTFLGLDDLEYL

SLITRK1

121

Q96PX8
LRVLLSADLKGFQYF

SLC26A11

556

Q86WA9
FGQNYKRIFILLEEL

SAGE2P

546

A6NJ88
FFSLLIKDIYFLNEG

RASGEF1C

366

Q8N431
ALETDLYKRFILVLN

XRCC4

171

Q13426
RFLKLLRFYIALTGI

NDUFB5

66

O43674
FELILAANYLDIKGL

SKP1

101

P63208
NATDRKYLVIGDLLF

nan

96

A8MWL6
TFLSLRDVFGKDLIY

F3

171

P13726
RTAKLNLLLGLFYVF

UBIAD1

311

Q9Y5Z9
LIKDVLYEFRLVAFA

IGSF9

686

Q9P2J2
IIDGFKFDLRIYVLV

TTLL6

211

Q8N841
SLLLELAGFLVFLRY

SLC66A3

41

Q8N755
RGLQFLLKYITGDNL

TRAV3

61

A0A0B4J244
ETLKFYLRIILGANA

TMEM208

21

Q9BTX3
YRKLLSLGFLAQDSV

ZIM2

126

Q9NZV7
LGLILLNEKYFSDLR

XPO7

1006

Q9UIA9
FLAILKESRFYETLQ

ZKSCAN2

351

Q63HK3
KIVDDFFIGRYVLLA

TMEM218

71

A2RU14
LGAEAFLLRLYRKTF

ERCC4

426

Q92889
GRTNLFYKLLSTFDL

SLC27A6

381

Q9Y2P4
AILRIIYFADAELLK

TRIP12

861

Q14669
IEEKLLLKLLSFFGY

VPS13D

3941

Q5THJ4
FSIILDFLYSGKLDL

ZBTB8B

76

Q8NAP8
YLQEAFFGKELLDLS

KMT2D

1771

O14686
FQTEGKLYLILDFLR

RPS6KA1

131

Q15418
KLYLILDFLRGGDLF

RPS6KA1

136

Q15418
ISLKDRFGFSLYIAL

MYO7A

1291

Q13402