Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	myosin filament	MYH1 MYH3 MYH4 MYO18B	3.10e-05	25	153	4	GO:0032982
GeneOntologyCellularComponent	myosin II complex	MYH1 MYH3 MYH4 MYO18B	4.93e-05	28	153	4	GO:0016460
GeneOntologyCellularComponent	myosin complex	MYH1 MYH3 MYH4 MYH16 MYO18B	7.16e-05	59	153	5	GO:0016459
GeneOntologyCellularComponent	muscle myosin complex	MYH1 MYH3 MYH4	2.01e-04	16	153	3	GO:0005859
Domain	Myosin-like_IQ_dom	MYH1 MYH3 MYH4 MYO18B	1.45e-05	19	151	4	IPR027401
Domain	-	MYH1 MYH3 MYH4 MYO18B	1.45e-05	19	151	4	4.10.270.10
Domain	DDI1_N	DDI2 DDI1	6.49e-05	2	151	2	IPR033882
Domain	PROTEIN_KINASE_ATP	ERBB3 VRK1 MYLK TRIO KALRN MARK3 SPEG SRPK2 ZAP70 BMPR1A IGF1R ULK4 WEE2	9.30e-05	459	151	13	PS00107
Domain	Kinase-like_dom	SMG1 ERBB3 VRK1 MYLK TRIO KALRN MARK3 SPEG SRPK2 ZAP70 BMPR1A IGF1R ULK4 WEE2	1.32e-04	542	151	14	IPR011009
Domain	Prot_kinase_dom	ERBB3 VRK1 MYLK TRIO KALRN MARK3 SPEG SRPK2 ZAP70 BMPR1A IGF1R ULK4 WEE2	1.74e-04	489	151	13	IPR000719
Domain	PLAC	ADAMTS19 ADAMTSL1 ADAMTS17	1.77e-04	14	151	3	PF08686
Domain	PROTEIN_KINASE_DOM	ERBB3 VRK1 MYLK TRIO KALRN MARK3 SPEG SRPK2 ZAP70 BMPR1A IGF1R ULK4 WEE2	1.88e-04	493	151	13	PS50011
Domain	Myosin_N	MYH1 MYH3 MYH4	2.19e-04	15	151	3	PF02736
Domain	Myosin_N	MYH1 MYH3 MYH4	2.19e-04	15	151	3	IPR004009
Domain	Myosin_head_motor_dom	MYH1 MYH3 MYH4 MYO18B	2.45e-04	38	151	4	IPR001609
Domain	MYOSIN_MOTOR	MYH1 MYH3 MYH4 MYO18B	2.45e-04	38	151	4	PS51456
Domain	Myosin_head	MYH1 MYH3 MYH4 MYO18B	2.45e-04	38	151	4	PF00063
Domain	MYSc	MYH1 MYH3 MYH4 MYO18B	2.45e-04	38	151	4	SM00242
Domain	Myosin_tail_1	MYH1 MYH3 MYH4	3.87e-04	18	151	3	PF01576
Domain	Myosin_tail	MYH1 MYH3 MYH4	3.87e-04	18	151	3	IPR002928
Domain	ARM-type_fold	SMG1 DNAJC13 XPO4 NCBP1 HUWE1 USP9Y MROH2B ULK4 NIPBL EIF3M	4.44e-04	339	151	10	IPR016024
Domain	PLAC	ADAMTS19 ADAMTSL1 ADAMTS17	4.56e-04	19	151	3	PS50900
Domain	PLAC	ADAMTS19 ADAMTSL1 ADAMTS17	4.56e-04	19	151	3	IPR010909
Domain	Asp_protease	DDI2 DDI1	6.39e-04	5	151	2	PF09668
Domain	Peptidase_aspartic_DDI1-type	DDI2 DDI1	6.39e-04	5	151	2	IPR019103
Domain	Somatotropin_CS	GH1 GH2	6.39e-04	5	151	2	IPR018116
Domain	PROTEIN_KINASE_ST	VRK1 MYLK TRIO KALRN MARK3 SPEG SRPK2 BMPR1A ULK4 WEE2	7.38e-04	362	151	10	PS00108
Domain	Peptidase_M12B_ADAM-TS	ADAMTS19 ADAMTSL1 ADAMTS17	9.26e-04	24	151	3	IPR013273
Domain	SOMATOTROPIN_2	GH1 GH2	9.53e-04	6	151	2	PS00338
Domain	SOMATOTROPIN_1	GH1 GH2	9.53e-04	6	151	2	PS00266
Domain	Hormone_1	GH1 GH2	9.53e-04	6	151	2	PF00103
Domain	Protein_kinase_ATP_BS	VRK1 MYLK KALRN MARK3 SPEG SRPK2 ZAP70 BMPR1A IGF1R WEE2	1.05e-03	379	151	10	IPR017441
Domain	-	GPD2 FOXRED1 TXNRD2 MICAL3	1.09e-03	56	151	4	3.50.50.60
Domain	Pkinase	VRK1 MYLK TRIO KALRN MARK3 SPEG SRPK2 BMPR1A ULK4 WEE2	1.09e-03	381	151	10	PF00069
Domain	FAD/NAD-binding_dom	GPD2 FOXRED1 TXNRD2 MICAL3	1.16e-03	57	151	4	IPR023753
Domain	Somatotropin	GH1 GH2	1.33e-03	7	151	2	IPR001400
Domain	Recep_L_domain	ERBB3 IGF1R	1.33e-03	7	151	2	PF01030
Domain	Furin-like	ERBB3 IGF1R	1.33e-03	7	151	2	PF00757
Domain	Rcpt_L-dom	ERBB3 IGF1R	1.33e-03	7	151	2	IPR000494
Domain	Furin-like_Cys-rich_dom	ERBB3 IGF1R	1.33e-03	7	151	2	IPR006211
Domain	-	ERBB3 IGF1R	1.33e-03	7	151	2	3.80.20.20
Domain	ARM-like	SMG1 DNAJC13 XPO4 HUWE1 USP9Y MROH2B ULK4 NIPBL	1.61e-03	270	151	8	IPR011989
Domain	DH_1	TRIO KALRN TIAM1 PREX1	1.69e-03	63	151	4	PS00741
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	MYH4 DSC1 NUP85 COPA MARK3 KRT35 IARS1 PSMA6 NUP88 KRI1 SHMT2 HUWE1 DIS3 DHX8 IVNS1ABP LRPPRC KLHL9 CTPS2 KLHL42 DDX23 ABCC12 EIF3D USP15 EIF3M KRT36 NIN	5.63e-13	1005	156	26	19615732
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	MYH4 MARK3 KRT35 IARS1 PSMA6 NELFB SHMT2 XPO4 SPIRE1 SRPK2 RB1CC1 PRKRA GH1 LRPPRC IGF1R TIAM1 FDFT1 EIF4EBP1 DDX23 EIF3D USP15 PREX1 EIF3M KRT36 DYNC1H1	6.68e-10	1284	156	25	17353931
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	THOC1 GPD2 DCAKD SMG1 NUP85 COPA MARK3 ST7 PSMA6 VPS8 KRI1 SHMT2 XPO4 NCBP1 HUWE1 DIS3 PRKRA LRPPRC NOP58 FDFT1 DDX23 MICAL3 EIF3D EIF3M DYNC1H1 HSP90AA1	1.43e-09	1440	156	26	30833792
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	GPD2 DCAKD DNAJC13 COPA TRIO ST7 KRI1 SHMT2 XPO4 NCBP1 HUWE1 RB1CC1 ITGA5 ANKLE2 PTPN7 TIAM1 PTPRK FDFT1 SBF2 MICAL3 HSP90AA1 NIN	2.06e-09	1049	156	22	27880917
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	THOC1 GPD2 VRK1 DSC1 COPA TRIO IARS1 PSMA6 NUP88 KRI1 SHMT2 DUOX2 NCBP1 HUWE1 DIS3 DHX8 IVNS1ABP LRPPRC NOP58 RBPJ EIF3D MYO18B NIPBL EIF3M DYNC1H1	5.46e-09	1425	156	25	30948266
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	SMG1 MYH1 MYH3 MYH4 STIM2 FOXRED1 MYLK NUP85 ACACB COPA PSMA6 DUOX2 NCBP1 FNBP1L STOX1 PDE10A ANKLE2 KRT73 CCDC148 LRPPRC BMPR1A DDX23 PREX1 NIPBL HSP90AA1	6.92e-09	1442	156	25	35575683
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	DCAKD HAUS6 GRIPAP1 DNAJC13 IFT20 IARS1 NUP88 SHMT2 XPO4 SPIRE1 ANKLE2 DIS3 IVNS1ABP LRPPRC TIAM1 C3 KATNIP EIF3D USP15 EIF3M DYNC1H1 HSP90AB3P	1.23e-07	1321	156	22	27173435
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	GPD2 GRIPAP1 VRK1 DNAJC13 DSC1 COPA IARS1 PSMA6 SHMT2 NCBP1 FNBP1L HUWE1 DIS3 PRKRA LRPPRC NOP58 SPATS2L FDFT1 DHRS7 EIF3D EIF3M HSP90AA1	2.21e-07	1367	156	22	32687490
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	OR51A4 MYH1 MYH3 MYH4 IARS1 NELFB DDI2 NCBP1 SLC28A3 HUWE1 STOX1 IVNS1ABP MCM3AP EIF3D DYNC1H1 FBXO34	2.34e-07	736	156	16	29676528
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	MYH1 MYH3 MYH4 DSC1 COPA IARS1 PSMA6 XPO4 NCBP1 HUWE1 LRPPRC IL1R2 C3 EIF3M DYNC1H1	2.53e-07	647	156	15	26618866
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	COPA NUP88 KRI1 NCBP1 HUWE1 DIS3 DHX8 PRKRA LRPPRC NOP58 MCM3AP DDX23 EIF3D NIPBL DYNC1H1	2.85e-07	653	156	15	22586326
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	HAUS6 GRIPAP1 ACACB TRIO ST7 NUP88 KRI1 SHMT2 ACE ANKLE2 KLHL9 MICAL3 MGA USP15 DYNC1H1 HSP90AA1 NIN	3.26e-07	853	156	17	28718761
Pubmed	Three linked myosin heavy chain genes clustered within 370 kb of each other show independent transcriptional and post-transcriptional regulation during differentiation of a mouse muscle cell line.	MYH1 MYH3 MYH4	3.53e-07	4	156	3	1985022
Pubmed	Smooth muscle myosin light chain kinase expression in cardiac and skeletal muscle.	MYH1 MYH4 MYLK	3.53e-07	4	156	3	11029314
Pubmed	Human MYO18B, a novel unconventional myosin heavy chain expressed in striated muscles moves into the myonuclei upon differentiation.	MYH1 MYH4 MYO18B	3.53e-07	4	156	3	12547197
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	THOC1 GPD2 VRK1 DNAJC13 COPA KALRN SHMT2 NCBP1 USP9Y DHX8 PRKRA LRPPRC NOP58 DHRS7 DDX23 EIF3D NIPBL DYNC1H1 HSP90AA1	4.36e-07	1082	156	19	38697112
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	ADAMTSL1 ZNF862 JAKMIP2 MCM3AP KATNIP MGA USP15	5.03e-07	105	156	7	9628581
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	VRK1 FOXRED1 NUP85 ACACB COPA IARS1 PSMA6 KRI1 SHMT2 NCBP1 HUWE1 DIS3 LRPPRC NOP58 FDFT1 DDX23 EIF3D NIPBL EIF3M DYNC1H1 HSP90AA1	5.03e-07	1318	156	21	30463901
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	TRIO IFT20 IARS1 PSMA6 KRI1 SRPK2 HUWE1 RB1CC1 BMPR1A RBPJ DYNC1H1	7.26e-07	358	156	11	32460013
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	THOC1 COPA MARK3 IARS1 SHMT2 SRPK2 NCBP1 HUWE1 DIS3 DHX8 PRKRA LRPPRC BMPR1A NOP58 IGF1R EIF3D MGA USP15 DYNC1H1 HSP90AA1	8.70e-07	1247	156	20	27684187
Pubmed	Developmental pattern of mouse skeletal myosin heavy chain gene transcripts in vivo and in vitro.	MYH1 MYH3 MYH4	8.79e-07	5	156	3	3829126
Pubmed	Sequential accumulation of mRNAs encoding different myosin heavy chain isoforms during skeletal muscle development in vivo detected with a recombinant plasmid identified as coding for an adult fast myosin heavy chain from mouse skeletal muscle.	MYH1 MYH3 MYH4	8.79e-07	5	156	3	6196357
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	FOXRED1 IARS1 PSMA6 SHMT2 HUWE1 RB1CC1 DIS3 IVNS1ABP LRPPRC DDX23 EIF3D MGA HSP90AA1	1.36e-06	551	156	13	34728620
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ERBB3 FOXRED1 COPA TRIO KALRN LRSAM1 SRPK2 NCBP1 HUWE1 USP9Y PRKRA TIAM1 PTPRK GPSM2 SPRED1 EIF3D PREX1 NIPBL DYNC1H1 HSP90AA1	1.38e-06	1285	156	20	35914814
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	GPD2 COPA IARS1 NELFB KRI1 SHMT2 SRPK2 NCBP1 FNBP1L HUWE1 DIS3 DHX8 LRPPRC NOP58 CTPS2 DDX23 EIF3D NIPBL EIF3M DYNC1H1 HSP90AA1	1.56e-06	1415	156	21	28515276
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	NUP85 COPA IARS1 XPO4 NCBP1 SYS1 HUWE1 IVNS1ABP LRPPRC FDFT1 MGA USP15 EIF3M HSP90AA1	1.74e-06	657	156	14	36180527
Pubmed	Distinct myogenic programs of embryonic and fetal mouse muscle cells: expression of the perinatal myosin heavy chain isoform in vitro.	MYH1 MYH3 MYH4	1.75e-06	6	156	3	1728586
Pubmed	Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved.	MYH1 MYH3 MYH4	1.75e-06	6	156	3	10077619
Pubmed	Deleting IGF-1 receptor from forebrain neurons confers neuroprotection during stroke and upregulates endocrine somatotropin.	GH1 GH2 IGF1R	1.75e-06	6	156	3	26762506
Pubmed	Spatial and temporal changes in myosin heavy chain gene expression in skeletal muscle development.	MYH1 MYH3 MYH4	1.75e-06	6	156	3	10588881
Pubmed	Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.	COPA IARS1 PSMA6 HUWE1 IVNS1ABP LRPPRC CHCHD4 KLHL9 KLHL42 EIF3D USP15 HSP90AA1	2.67e-06	495	156	12	28581483
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	THOC1 SMG1 MYH3 NUP85 KRI1 SRPK2 KRT73 NOP58 EIF3D MGA NIPBL	2.70e-06	410	156	11	26949251
Pubmed	A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling.	THOC1 DSC1 COPA IARS1 PSMA6 SHMT2 NCBP1 HUWE1 DHX8 LRPPRC NOP58 DDX23 EIF3D EIF3M DYNC1H1	2.83e-06	786	156	15	29128334
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	DNAJC13 DSC1 COPA IARS1 LRSAM1 PSMA6 SHMT2 HUWE1 DIS3 PRKRA LRPPRC NOP58 MCM3AP DDX23 EIF3D MGA NIPBL EIF3M DYNC1H1 HSP90AA1	3.01e-06	1353	156	20	29467282
Pubmed	A population-based study of IGF axis polymorphisms and the esophageal inflammation, metaplasia, adenocarcinoma sequence.	GH1 GH2 IGF1R	3.06e-06	7	156	3	20403354
Pubmed	Mode of growth hormone action in osteoblasts.	GH1 GH2 IGF1R	3.06e-06	7	156	3	17698843
Pubmed	Elevated GH/IGF-I, due to somatotrope-specific loss of both IGF-I and insulin receptors, alters glucose homeostasis and insulin sensitivity in a diet-dependent manner.	GH1 GH2 IGF1R	3.06e-06	7	156	3	21990313
Pubmed	A fast Myosin super enhancer dictates muscle fiber phenotype through competitive interactions with Myosin genes.	MYH1 MYH3 MYH4	3.06e-06	7	156	3	35210422
Pubmed	ANKK1 is found in myogenic precursors and muscle fibers subtypes with glycolytic metabolism.	MYH1 MYH3 MYH4	3.06e-06	7	156	3	29758057
Pubmed	Diversity in transcriptional start site selection and alternative splicing affects the 5'-UTR of mouse striated muscle myosin transcripts.	MYH1 MYH3 MYH4	3.06e-06	7	156	3	16819597
Pubmed	Charting the molecular network of the drug target Bcr-Abl.	DSC1 KRT35 IARS1 USP9Y KRT73 USP15 KRT36 DYNC1H1 HSP90AA1	3.51e-06	266	156	9	19380743
Pubmed	The sperm-associated antigen 6 interactome and its role in spermatogenesis.	SMG1 ST7 NUP88 C20orf96 GPSM2 HFM1 NIPBL EIF3M	3.51e-06	199	156	8	31146259
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	DNAJC13 COPA IARS1 SRPK2 DIS3 PRKRA LRPPRC NOP58 SPATS2L SBF2 C3 EIF3D DYNC1H1	3.52e-06	601	156	13	33658012
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	THOC1 GPD2 NUP85 COPA IARS1 SHMT2 NCBP1 HUWE1 RB1CC1 DHX8 LRPPRC NOP58 DDX23 EIF3D MGA NIPBL DYNC1H1	3.89e-06	1024	156	17	24711643
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	THOC1 DSC1 NUP85 COPA MARK3 IARS1 KRI1 SRPK2 NCBP1 DHX8 PRKRA LRPPRC NOP58 SPATS2L C3 EIF3D EIF3M DYNC1H1 HSP90AA1	3.94e-06	1257	156	19	36526897
Pubmed	Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.	COPA PSMA6 SHMT2 LRPPRC NOP58 DYNC1H1 HSP90AA1	4.19e-06	144	156	7	35681168
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	HAUS6 NUP85 COPA IFT20 NUP88 TUBGCP6 CHCHD4 BMPR1A NOP58 FBXO28 KLHL42 DDX23 MICAL3 EIF3D NIPBL EIF3M DYNC1H1 HSP90AA1	4.76e-06	1155	156	18	20360068
Pubmed	Islet insulin content and release are increased in male mice with elevated endogenous GH and IGF-I, without evidence of systemic insulin resistance or alterations in β-cell mass.	GH1 GH2 IGF1R	4.88e-06	8	156	3	25936582
Pubmed	Genes for skeletal muscle myosin heavy chains are clustered and are not located on the same mouse chromosome as a cardiac myosin heavy chain gene.	MYH1 MYH3 MYH4	4.88e-06	8	156	3	3864153
Pubmed	Long noncoding RNA lncMREF promotes myogenic differentiation and muscle regeneration by interacting with the Smarca5/p300 complex.	MYH1 MYH3 MYH4	4.88e-06	8	156	3	36200826
Pubmed	Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.	HAUS6 COPA IARS1 PSMA6 DDI2 HUWE1 DIS3 PRKRA LRPPRC EIF3D DYNC1H1 HSP90AA1	5.77e-06	534	156	12	35032548
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	DNAJC13 NUP85 COPA IARS1 NELFB NCBP1 HUWE1 DIS3 LRPPRC NOP58 EIF3D DYNC1H1 HSP90AA1	6.70e-06	638	156	13	33239621
Pubmed	Mechanism of repression of 11β-hydroxysteroid dehydrogenase type 1 by growth hormone in 3T3-L1 adipocytes.	GH1 GH2 IGF1R	7.29e-06	9	156	3	24759003
Pubmed	Physical and functional interaction of growth hormone and insulin-like growth factor-I signaling elements.	GH1 GH2 IGF1R	7.29e-06	9	156	3	15044591
Pubmed	Genetic map of nine polymorphic loci comprising a single linkage group on rat chromosome 10: evidence for linkage conservation with human chromosome 17 and mouse chromosome 11.	MYH3 GH1 GH2	7.29e-06	9	156	3	1358809
Pubmed	Rho-associated protein kinase-dependent moesin phosphorylation is required for PD-L1 stabilization in breast cancer.	VRK1 DSC1 NELFB SHMT2 HUWE1 DIS3 FDFT1 CD274	8.37e-06	224	156	8	32941674
Pubmed	The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets.	TSNAXIP1 GRIPAP1 MYLK PSMA6 HUWE1 RBPJ EIF3M HSP90AA1	8.64e-06	225	156	8	25277244
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	GRIPAP1 NUP85 COPA IARS1 LRSAM1 PSMA6 NUP88 NELFB SHMT2 DDI2 NCBP1 HUWE1 DIS3 IVNS1ABP CTPS2 EIF3D USP15 EIF3M DYNC1H1 HSP90AA1	8.80e-06	1455	156	20	22863883
Pubmed	SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.	DNAJC13 DSC1 IARS1 PSMA6 IVNS1ABP SPATS2L EIF3D MGA USP15 EIF3M DYNC1H1 HSP90AA1	8.97e-06	558	156	12	27591049
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	GPD2 HAUS6 NUP85 COPA NUP88 NELFB SHMT2 DHX8 LRPPRC FDFT1 DDX23 DYNC1H1	9.30e-06	560	156	12	35241646
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	DCAKD DNAJC13 TRIO MARK3 ST7 FBXL17 SPIRE1 SRPK2 FNBP1L HUWE1 PDE10A LRPPRC KLHL9 CMIP IGF1R SBF2 KATNIP MICAL3 USP15 EIF3M	1.23e-05	1489	156	20	28611215
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	VRK1 DNAJC13 COPA NCBP1 HUWE1 DHX8 GNA14 DDX23 DEPDC7 NIPBL DYNC1H1 HSP90AA1	1.36e-05	582	156	12	20467437
Pubmed	Calcineurin is necessary for the maintenance but not embryonic development of slow muscle fibers.	MYH1 MYH3 MYH4	1.42e-05	11	156	3	16024798
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	DSC1 NUP85 COPA IARS1 PSMA6 SHMT2 NCBP1 HUWE1 DIS3 LRPPRC NOP58 KLHL9 CTPS2 FDFT1 DDX23 USP15 DYNC1H1 HSP90AA1	1.49e-05	1257	156	18	37317656
Pubmed	DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization.	COPA IARS1 HUWE1 LRPPRC DYNC1H1 HSP90AA1 HSP90AB3P	1.50e-05	175	156	7	25756610
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	SMG1 MYH3 TRIO KALRN IVNS1ABP LRPPRC FDFT1 SPRED1 MYO18B MGA HSP90AA1	1.65e-05	497	156	11	23414517
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	MARK3 SPEG VPS8 EPM2AIP1 FBXO28 MCM3AP KATNIP MICAL3 USP15 DYNC1H1	1.66e-05	407	156	10	12693553
Pubmed	Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor.	COPA PSMA6 HUWE1 IVNS1ABP LRPPRC FDFT1 MGA USP15 EIF3M HSP90AA1	1.70e-05	408	156	10	33766124
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	COPA KRT35 IARS1 PSMA6 KRI1 NCBP1 USP9Y KRT73 LRPPRC NOP58 FDFT1 EIF3D EIF3M KRT36 DYNC1H1 HSP90AA1 HSP90AB3P	1.81e-05	1153	156	17	29845934
Pubmed	Promoting anti-tumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylation.	COPA HUWE1 LRPPRC CD274 EIF3D	1.87e-05	72	156	5	36376293
Pubmed	H19X-encoded miR-322(424)/miR-503 regulates muscle mass by targeting translation initiation factors.	IGF1R EIF4EBP1 EIF3M	1.89e-05	12	156	3	34704401
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	VRK1 COPA NUP88 NELFB SHMT2 HUWE1 DHX8 PRKRA NOP58 CTPS2 EIF3D NIPBL DYNC1H1	1.89e-05	704	156	13	29955894
Pubmed	Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome.	SRPK2 DDX23	2.00e-05	2	156	2	18425142
Pubmed	Dual targeting of IGF-1R and ErbB3 as a potential therapeutic regimen for ovarian cancer.	ERBB3 IGF1R	2.00e-05	2	156	2	31728045
Pubmed	Functional and prognostic role of ZAP-70 in chronic lymphocytic leukaemia.	ZAP70 HSP90AA1	2.00e-05	2	156	2	16300468
Pubmed	Hsp90 up-regulates PD-L1 to promote HPV-positive cervical cancer via HER2/PI3K/AKT pathway.	CD274 HSP90AA1	2.00e-05	2	156	2	34666670
Pubmed	Growth and muscle defects in mice lacking adult myosin heavy chain genes.	MYH1 MYH4	2.00e-05	2	156	2	9382868
Pubmed	Postnatal myosin heavy chain isoform expression in normal mice and mice null for IIb or IId myosin heavy chains.	MYH1 MYH4	2.00e-05	2	156	2	11150240
Pubmed	Heat shock protein 90-sheltered overexpression of insulin-like growth factor 1 receptor contributes to malignancy of thymic epithelial tumors.	IGF1R HSP90AA1	2.00e-05	2	156	2	21372220
Pubmed	HUWE1 ubiquitylates and degrades the RAC activator TIAM1 promoting cell-cell adhesion disassembly, migration, and invasion.	HUWE1 TIAM1	2.00e-05	2	156	2	25543140
Pubmed	ZAP-70 is a novel conditional heat shock protein 90 (Hsp90) client: inhibition of Hsp90 leads to ZAP-70 degradation, apoptosis, and impaired signaling in chronic lymphocytic leukemia.	ZAP70 HSP90AA1	2.00e-05	2	156	2	15972449
Pubmed	Kalirin and Trio proteins serve critical roles in excitatory synaptic transmission and LTP.	TRIO KALRN	2.00e-05	2	156	2	26858404
Pubmed	The human growth hormone gene family: structure and evolution of the chromosomal locus.	GH1 GH2	2.00e-05	2	156	2	6306568
Pubmed	Molecular cloning and characterization of a novel nuclear protein kinase in mice.	VRK1 C3	2.00e-05	2	156	2	9521809
Pubmed	IGF-1R and ErbB3/HER3 contribute to enhanced proliferation and carcinogenesis in trastuzumab-resistant ovarian cancer model.	ERBB3 IGF1R	2.00e-05	2	156	2	23792093
Pubmed	Role of some vasoactive mediators in patients with erectile dysfunction: their relationship with angiotensin-converting enzyme and growth hormone.	ACE GH1	2.00e-05	2	156	2	14671660
Pubmed	Haplotype of growth hormone and angiotensin I-converting enzyme genes, serum angiotensin I-converting enzyme and ventricular growth: pathway inference in pharmacogenetics.	ACE GH1	2.00e-05	2	156	2	17496728
Pubmed	Intermolecular relations between the glucocorticoid receptor, ZAP-70 kinase, and Hsp-90.	ZAP70 HSP90AA1	2.00e-05	2	156	2	17222799
Pubmed	MM-141, an IGF-IR- and ErbB3-directed bispecific antibody, overcomes network adaptations that limit activity of IGF-IR inhibitors.	ERBB3 IGF1R	2.00e-05	2	156	2	24282274
Pubmed	Hsp90α forms a stable complex at the cilium neck for the interaction of signalling molecules in IGF-1 receptor signalling.	IGF1R HSP90AA1	2.00e-05	2	156	2	25359884
Pubmed	Phosphorylation of P-Rex1 at serine 1169 participates in IGF-1R signaling in breast cancer cells.	IGF1R PREX1	2.00e-05	2	156	2	23899556
Pubmed	Skeletal muscle adaptations in response to voluntary wheel running in myosin heavy chain null mice.	MYH1 MYH4	2.00e-05	2	156	2	11744674
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	NUP85 NUP88 KRI1 NCBP1 HUWE1 DHX8 PRKRA SPATS2L MCM3AP	2.06e-05	332	156	9	25693804
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	MYLK COPA IARS1 FNBP1L PRKRA LRPPRC NOP58 SPATS2L FDFT1 C3 EIF3D EIF3M DYNC1H1	2.10e-05	711	156	13	33022573
Pubmed	Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.	IARS1 PSMA6 SHMT2 SRPK2 NCBP1 DIS3 DHX8 PRKRA NOP58 DDX23 EIF3D DYNC1H1 HSP90AA1	2.19e-05	714	156	13	28302793
Pubmed	Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants.	COPA IARS1 PSMA6 HUWE1 LRPPRC DYNC1H1 HSP90AA1 HSP90AB3P	2.19e-05	256	156	8	35777956
Pubmed	Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase.	IARS1 HUWE1 RB1CC1 IVNS1ABP MGA USP15 DYNC1H1 HSP90AA1	2.19e-05	256	156	8	32698014
Pubmed	Contractile protein gene expression in primary myotubes of embryonic mouse hindlimb muscles.	MYH1 MYH3 MYH4	2.45e-05	13	156	3	8404542
Pubmed	ZFP36L2 is a cell cycle-regulated CCCH protein necessary for DNA lesion-induced S-phase arrest.	USP9Y IVNS1ABP LRPPRC C3 MGA EIF3M HSP90AA1	2.46e-05	189	156	7	29449217
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	THOC1 TSNAXIP1 GIMAP4 SRPK2 DHX8 PRKRA NOP58 SPATS2L DDX23 HFM1 EIF3D HSP90AA1 NIN	2.49e-05	723	156	13	34133714
Interaction	CD274 interactions	VRK1 DSC1 NUP85 COPA NELFB SHMT2 XPO4 HUWE1 DIS3 LRPPRC FDFT1 CD274 EIF3D	4.03e-06	369	150	13	int:CD274
Interaction	ADRM1 interactions	GRIPAP1 PSMA6 DDI2 NCBP1 DDI1 HUWE1 LRPPRC INSIG2 USP15 DYNC1H1 HSP90AA1	5.09e-06	266	150	11	int:ADRM1
Interaction	ASAH2 interactions	MYH1 MYH3 MYH4	7.95e-06	6	150	3	int:ASAH2
Interaction	GRK7 interactions	DSC1 ACACB HSP90AA1 HSP90AB3P	3.30e-05	25	150	4	int:GRK7
Interaction	RIT1 interactions	THOC1 SMG1 HAUS6 NUP85 COPA IARS1 POLE2 PSMA6 NUP88 NELFB SRPK2 NCBP1 SYS1 ANKLE2 DIS3 ZAP70 DHX8 LRPPRC CHCHD4 NOP58 IGF1R DDX23 NIPBL	4.01e-05	1230	150	23	int:RIT1
Interaction	CCHCR1 interactions	HAUS6 GRIPAP1 IKZF3 TRIML2 IFT20 KRT35 TEKT1 KRT36 NIN	5.59e-05	229	150	9	int:CCHCR1
Interaction	RUVBL2 interactions	SMG1 IKZF3 DDI2 NCBP1 HUWE1 LRPPRC BMPR1A NOP58 FDFT1 CD274 MGA USP15 NIPBL DYNC1H1 HSP90AA1	5.79e-05	616	150	15	int:RUVBL2
Interaction	NUAK2 interactions	GRIPAP1 MARK3 FNBP1L HSP90AA1 HSP90AB3P	6.01e-05	56	150	5	int:NUAK2
Interaction	CDK11A interactions	DHX8 IVNS1ABP NOP58 DDX23 EIF3D USP15 HSP90AA1 HSP90AB3P	6.20e-05	180	150	8	int:CDK11A
Interaction	PRMT1 interactions	THOC1 FOXRED1 IARS1 SPEG PSMA6 VPS8 FBXL17 SHMT2 HUWE1 RB1CC1 DIS3 IVNS1ABP LRPPRC PTPN7 DDX23 EIF3D MGA USP15 HSP90AA1	6.24e-05	929	150	19	int:PRMT1
Interaction	INSRR interactions	DCAKD ANKLE2 BMPR1A IGF1R HSP90AA1 HSP90AB3P	6.88e-05	93	150	6	int:INSRR
Interaction	BCAP31 interactions	MYH1 MYH3 MYH4 STIM2 COPA ST7 SHMT2 HUWE1 ITGA5 ANKLE2 LRPPRC FDFT1 DHRS7 HSP90AA1	6.97e-05	554	150	14	int:BCAP31
Interaction	ATG101 interactions	MYH4 DSC1 COPA HUWE1 RB1CC1 LRPPRC	7.31e-05	94	150	6	int:ATG101
GeneFamily	Myosin heavy chains	MYH1 MYH3 MYH4 MYH16	1.45e-06	15	106	4	1098
GeneFamily	Growth hormone family	GH1 GH2	5.03e-04	6	106	2	1175
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	TRIO KALRN TIAM1 PREX1	6.08e-04	66	106	4	722
GeneFamily	Kelch like\|BTB domain containing	IVNS1ABP KLHL9 KLHL42	1.90e-03	42	106	3	617
GeneFamily	Olfactory receptors, family 51	OR51A4 OR51A2 OR51E1	2.18e-03	44	106	3	164
GeneFamily	Eukaryotic translation initiation factor 3	EIF3D EIF3M	2.55e-03	13	106	2	1121
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	ADAMTSL1 MYLK TRIO KALRN SPEG	2.59e-03	161	106	5	593
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	VRK1 DNAJC13 TRIO MARK3 SRPK2 FNBP1L RB1CC1 TRAPPC8 ANKLE2 LRPPRC BMPR1A IGF1R TIAM1 PTPRK RBPJ MICAL3 USP15 NIPBL	3.36e-06	856	155	18	M4500
Coexpression	PAL_PRMT5_TARGETS_UP	HAUS6 DNAJC13 NUP85 ST7 POLE2 NUP88 NOP58 CTPS2 PTPRK	3.70e-06	204	155	9	M10688
Coexpression	PAL_PRMT5_TARGETS_UP	HAUS6 DNAJC13 NUP85 ST7 POLE2 NUP88 NOP58 CTPS2 PTPRK	4.69e-06	210	155	9	MM1172
Coexpression	LEE_BMP2_TARGETS_DN	HAUS6 VRK1 FOXRED1 NUP85 IARS1 POLE2 NUP88 SHMT2 XPO4 DDI2 NCBP1 DIS3 LRPPRC CHCHD4 NOP58 TIAM1 HSP90AA1 NIN	9.30e-06	922	155	18	MM1068
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	GIMAP4 SMG1 HAUS6 STIM2 IKZF3 MARK3 KRI1 XPO4 HUWE1 RB1CC1 TRAPPC8 ANKLE2 ZAP70 IVNS1ABP PTPN7 DHRS7 RBPJ USP15 PREX1 NIPBL DYNC1H1 CLEC2B NIN	2.35e-05	1492	155	23	M40023
Coexpression	GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_UP	THOC1 MYH3 DNAJC13 KRI1 KLHL9 ZNF540 MCM3AP MGA	2.45e-05	198	155	8	M6109
Coexpression	LEE_BMP2_TARGETS_DN	HAUS6 VRK1 FOXRED1 NUP85 IARS1 POLE2 NUP88 SHMT2 XPO4 NCBP1 DIS3 LRPPRC CHCHD4 NOP58 TIAM1 HSP90AA1 NIN	2.69e-05	904	155	17	M2325
ToppCell	343B-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PLVAP MYLK FNBP1L ACE IVNS1ABP PTPRK CD274 PREX1 CLEC2B	1.84e-08	186	154	9	dae6a98963c78bf7518ebab8dc02f173c3b0f7f7
ToppCell	343B-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PLVAP MYLK FNBP1L ACE IVNS1ABP PTPRK CD274 PREX1 CLEC2B	1.84e-08	186	154	9	080e56113b89138277a2bd2eabddfa6cd1a18b61
ToppCell	COVID-19-kidney-Stressed_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PLVAP KALRN ITGA5 PDE10A IVNS1ABP GNA14 HSP90AA1 CLEC2B	2.13e-07	179	154	8	754f69bac7a1d5137f5141f6193285ccbfe361cb
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	COL19A1 TRIO FBXL17 SRPK2 CMIP IGF1R PTPRK SBF2	3.64e-07	192	154	8	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	COPD-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	ADAMTSL1 PLVAP TRIO PDE10A LRPPRC NOP58 CMIP SPRED1	3.94e-07	194	154	8	8dcde77767b23e75360adb316cdccf56a00e3726
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	THOC1 ACE CTPS2 IL1R2 FBXO28 CD274 KLHL42	3.78e-06	185	154	7	e06a784a297f357f3f8e761c24fa70722048ab42
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PLVAP KALRN ITGA5 PDE10A IVNS1ABP GNA14 CLEC2B	3.78e-06	185	154	7	673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 COPA SPIRE1 HUWE1 PDE10A SPRED1 HSP90AA1	3.78e-06	185	154	7	eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	SRPK2 ACE ZAP70 FDFT1 PREX1 FBXO34 NIN	4.51e-06	190	154	7	91ba66d4b56c59523485b17738e93f14bb00afa4
ToppCell	COVID-19-lung-Vein_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADAMTSL1 PLVAP KALRN ITGA5 PDE10A GNA14 CLEC2B	4.51e-06	190	154	7	1caeaef78326734c1e31a0c4739190d5c5a77b9e
ToppCell	COVID-19-kidney-Stressed_EC\|kidney / Disease (COVID-19 only), tissue and cell type	PLVAP KALRN DDI1 ITGA5 GNA14 HSP90AA1 CLEC2B	4.67e-06	191	154	7	d35aa842b813ea0eff7362abc894cca4e86b2fb2
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	ADAMTS19 ERBB3 RB1CC1 PTPRK INSIG2 NIPBL HSP90AA1	4.83e-06	192	154	7	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	DDI2 HUWE1 LRPPRC PTPRK SBF2 MGA DYNC1H1	5.00e-06	193	154	7	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-11\|TCGA-Brain / Sample_Type by Project: Shred V9	IKZF3 COL19A1 ZAP70 KRT73 GNA14 EDDM3B	5.36e-06	127	154	6	7c3f8c791567fff5d2f42c2c7d09c78ec6ca3afe
ToppCell	368C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	GIMAP4 ZAP70 PTPN7 DHRS7 RBPJ HSP90AA1 CLEC2B	5.72e-06	197	154	7	d6eb843f5ee1b1ea54416ba6e987eefe86ca3216
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GIMAP4 PLVAP KALRN ITGA5 PDE10A GNA14 CLEC2B	5.91e-06	198	154	7	5c82dad416938d5c460069796d808170e7dbc8d9
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_vascular\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GIMAP4 PLVAP KALRN ITGA5 PDE10A GNA14 CLEC2B	5.91e-06	198	154	7	f7aa809040fa9f5782b92eec1f289d690eb5c7bd
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_CTL\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IKZF3 JAKMIP2 ZAP70 PTPN7 PREX1 HSP90AA1 CLEC2B	6.31e-06	200	154	7	893bb7c25ad7c6589a4c7c0364c2ace666e9b4be
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Astrocyte\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	DCAKD ZNF862 ZDBF2 ITGA5 CTPS2 TEKT1	1.02e-05	142	154	6	85e573616e54d41391b4ad8c3d38e4ca92112673
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-T-T_CD8-MAIT\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GIMAP4 IKZF3 ZAP70 CACNA1I PREX1 CLEC2B	1.34e-05	149	154	6	f4bee5fdaaa4a1917e403de90e5a62353006df24
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-Activated_T\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LRRC63 GIMAP4 IKZF3 ZAP70 PTPN7 KATNIP	2.46e-05	166	154	6	fb2cfbf1d0a0f1950dd24c08ba00ebd64b06ceb4
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9\|TCGA-Bladder / Sample_Type by Project: Shred V9	GPD2 DUOX2 DIS3 CMIP PTPRK FBXO34	2.91e-05	171	154	6	adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP4 PLVAP ACACB FABP9 DDI1 ABCC12	3.11e-05	173	154	6	a2c1ef3f4d7e9f68fc77ee7c42a4727bdea5da94
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Endothelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP4 PLVAP ACACB FABP9 DDI1 ABCC12	3.11e-05	173	154	6	4830136f1f1976e00ac9af9062a531ac42533041
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Endothelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP4 PLVAP ACACB FABP9 DDI1 ABCC12	3.11e-05	173	154	6	0b79e2a4fd19d524c24b69a6b524ffc6affdabe5
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASB14 ACE TUBGCP6 CMIP DPEP2 MYO18B	3.31e-05	175	154	6	c1c722db42da9b8a2a46e516ddb83d9be5e2e504
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_2\|356C / Donor, Lineage, Cell class and subclass (all cells)	THOC1 PTPN7 CTPS2 FBXO28 CD274 KLHL42	3.65e-05	178	154	6	8b939659f713eea50a1a6e28b571f680ca0b4c12
ToppCell	LPS_only-Lymphocytic_NKT-iNKT/MAIT\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GIMAP4 IKZF3 ZAP70 PTPN7 PREX1 CLEC2B	3.76e-05	179	154	6	de3ddc1264e43727be50d69b81cc84a3c91812a2
ToppCell	LPS_only-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GIMAP4 IKZF3 ZAP70 PTPN7 PREX1 CLEC2B	3.76e-05	179	154	6	def981e97e3ff9019910c9af3861ca0d08eb0d0f
ToppCell	NS-moderate-d_0-4-Lymphoid-CTL\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	GIMAP4 IKZF3 JAKMIP2 ZAP70 PTPN7 DPEP2	4.00e-05	181	154	6	7fb3c1d29c542a3cea7fa654432d501d82df138f
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ACE CTPS2 IL1R2 FBXO28 CD274 KLHL42	4.25e-05	183	154	6	f142b320023eef00b48d4820c46214c9794d37e7
ToppCell	droplet-Spleen-nan-21m-Lymphocytic-T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP4 ZAP70 PTPN7 IGF1R TIAM1 IL1R2	4.52e-05	185	154	6	ea3ff0bd3f312bd2e93227ecf6ed577366aab3e0
ToppCell	Control-Endothelial-Endothelial-Vein\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	STIM2 PLVAP KALRN SRPK2 PDE10A GNA14	4.66e-05	186	154	6	92092f11ecce22c14f244e42c499af0822977e6f
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	IFT20 VPS8 DDI2 NCBP1 SPATS2L DYNC1H1	4.80e-05	187	154	6	c8278525b3e1d3f3f4defcaf109cce22dd2e157a
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	SMG1 IKZF3 HUWE1 RB1CC1 NIPBL DYNC1H1	4.94e-05	188	154	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	COVID-19-lung-Vein_EC\|lung / Disease (COVID-19 only), tissue and cell type	ADAMTSL1 PLVAP KALRN PDE10A GNA14 CLEC2B	4.94e-05	188	154	6	d582b76fc2faac526c9bf97503041129e1a6a211
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	DDI2 TUBGCP6 SPATS2L TIAM1 DPEP2 KLHL42	4.94e-05	188	154	6	b1ec7c45aedcc3d22cac898c6a3679e7f8b44c77
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_3\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	IFT20 VPS8 DDI2 NCBP1 SPATS2L DYNC1H1	5.09e-05	189	154	6	99b01893da9f9f7c9528afaffad178285211738b
ToppCell	wk_20-22-Hematologic_Lymphocytic-NK-CD56bright_NK\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	GIMAP4 IKZF3 ZAP70 PTPN7 ADAMTS17 CLEC2B	5.24e-05	190	154	6	c8031df82c3662ce4140c850277987f7210e9bcd
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1\|367C / Donor, Lineage, Cell class and subclass (all cells)	GIMAP4 IKZF3 ZAP70 PTPN7 HSP90AA1 CLEC2B	5.24e-05	190	154	6	4240d52a465bc3f8016834b22a35c44ba2b0a9f4
ToppCell	NS-control-d_0-4-Lymphoid-CTL\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	GIMAP4 IKZF3 JAKMIP2 ZAP70 PTPN7 PREX1	5.40e-05	191	154	6	27f2151da2f41015a979499f274ab1284a36189f
ToppCell	3'-GW_trimst-1-SmallIntestine-Hematopoietic-T_cells-NK_cell\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GIMAP4 IKZF3 ZAP70 KRT73 PTPN7 CLEC2B	5.40e-05	191	154	6	a467205078bec92562e4b6b1b2116b88f421e8ba
ToppCell	control-Lymphoid-CTL\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	GIMAP4 IKZF3 JAKMIP2 ZAP70 PTPN7 PREX1	5.40e-05	191	154	6	8df23473e24cfa51c09986102ddd391ed0f0b9cc
ToppCell	wk_15-18-Hematologic_Lymphocytic-NK-CD56bright_NK\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	GIMAP4 IKZF3 ZAP70 PTPN7 ADAMTS17 CLEC2B	5.55e-05	192	154	6	fedff776812c3d040d295ac8c806296e4018b247
ToppCell	COVID-19-kidney-Myeloid\|COVID-19 / Disease (COVID-19 only), tissue and cell type	IVNS1ABP IL1R2 RBPJ USP15 PREX1 HSP90AA1	5.55e-05	192	154	6	0b9d22a222f1201e375f8e55cace9ef939febae4
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	STIM2 IKZF3 COL19A1 NUP88 NOP58 MICAL3	5.72e-05	193	154	6	bbea475d2c4c7b29674ff302529f8f83dd666dcb
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	PLVAP KALRN ITGA5 IVNS1ABP GNA14 CLEC2B	5.72e-05	193	154	6	479abb1cd2eb978b8a4fdb900069a6329fc8cade
ToppCell	tumor_Lung-T/NK_cells-CD8_low_T\|tumor_Lung / Location, Cell class and cell subclass	GIMAP4 IKZF3 ZAP70 PTPN7 HSP90AA1 CLEC2B	5.88e-05	194	154	6	21d789585b3085aeeae3bef595c6cc5ea1c3dc4f
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GIMAP4 STIM2 XPO4 ASB14 ZAP70 NOP58	6.05e-05	195	154	6	4b9663509cc5e3f409f6d0d37640cb301a827d98
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	STIM2 IKZF3 COL19A1 NUP88 NOP58 MICAL3	6.05e-05	195	154	6	0c49d22c348aec6d8a1a976e7c88d0a3b48a4244
ToppCell	critical-Lymphoid-CTL\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	GIMAP4 SMG1 ZAP70 PTPN7 RBPJ CLEC2B	6.23e-05	196	154	6	c861f017aa9050282aa81c5a445bae399df00e4f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 PLVAP KALRN ITGA5 GNA14 PREX1	6.23e-05	196	154	6	ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	STIM2 IKZF3 COL19A1 NUP88 NOP58 MICAL3	6.23e-05	196	154	6	c225c8eb2fe9a10f0cf574c7d8b6206887aac2df
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Glia_progenitor_cell\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	TRIO NELFB FBXL17 ASB14 ANKLE2 MCM3AP	6.23e-05	196	154	6	7be50b9156394dea44d7b8b476d4dd516abfafae
ToppCell	wk_08-11-Endothelial-Blood_vessel_endothelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	GIMAP4 PLVAP ITGA5 ACE PREX1 CLEC2B	6.40e-05	197	154	6	2ed92f942475db6836e48da3c6b8235eb8691c38
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYH3 PLVAP CD274 C3 NLRP4 PREX1	6.40e-05	197	154	6	b597c292fc1cb381a4325fed15a32966c38def28
ToppCell	BL\|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	GIMAP4 IVNS1ABP IL1R2 USP15 PREX1 NIN	6.40e-05	197	154	6	1acf0191fa0a25cd20bfd9ea7bf727a1555986a1
ToppCell	Parenchymal-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTSL1 MYLK KALRN SPEG ITGA5 MICAL3	6.59e-05	198	154	6	bd42c03e384e64f61b02618cf1a5440033bb04b2
ToppCell	18-Distal-Endothelial-Endothelial\|Distal / Age, Tissue, Lineage and Cell class	GIMAP4 PLVAP ITGA5 ACE PREX1 CLEC2B	6.59e-05	198	154	6	efd3af3c0b4ab29605331ecdcb7a52cba38e6028
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	COL19A1 TRIO ST7 FBXL17 IGF1R PTPRK	6.59e-05	198	154	6	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	IPF-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	ADAMTSL1 PLVAP TRIO PDE10A CMIP SPRED1	6.59e-05	198	154	6	b8bd1ba268480f54451648e01631b615a3401144
ToppCell	18-Distal-Endothelial\|Distal / Age, Tissue, Lineage and Cell class	GIMAP4 PLVAP ITGA5 ACE PREX1 CLEC2B	6.59e-05	198	154	6	ee657a84928d54eb7a9a66c7acb19a7c119d6423
ToppCell	COVID-19_Moderate-CD8+_Tem\|COVID-19_Moderate / disease group, cell group and cell class	GIMAP4 IKZF3 JAKMIP2 ZAP70 PTPN7 CLEC2B	6.77e-05	199	154	6	adcaf9bd73933259dcf7983ca369a98e2f312d0b
ToppCell	367C-Endothelial_cells-Endothelial-A_(Artery)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PLVAP CMIP TIAM1 EIF3D EIF3M CLEC2B	6.77e-05	199	154	6	f53e0e4c34e6aec81ab07593aa11e045ba04df06
ToppCell	367C-Endothelial_cells-Endothelial-A_(Artery)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PLVAP CMIP TIAM1 EIF3D EIF3M CLEC2B	6.77e-05	199	154	6	62936fb64b33f7ad671f9c610bed665f17d3145e
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_CTL\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IKZF3 JAKMIP2 ZAP70 KRT73 PTPN7 PREX1	6.77e-05	199	154	6	eb188b0b457136b6ee485d3b3052baa30d9c0002
ToppCell	COVID-19_Severe-CD8+_T_activated\|COVID-19_Severe / disease group, cell group and cell class	GIMAP4 IKZF3 JAKMIP2 ZAP70 DHRS7 HSP90AA1	6.77e-05	199	154	6	a16b961996291bd5958c3851b7fdd7b45c53e19b
ToppCell	(01)_IL1RL1+-(2)_GFP_FOXI1\|(01)_IL1RL1+ / shred by cell type by condition	SRPK2 RB1CC1 SPATS2L NIPBL EIF3M HSP90AA1	6.77e-05	199	154	6	a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_TRM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IKZF3 JAKMIP2 ZAP70 PTPN7 PREX1 CLEC2B	6.96e-05	200	154	6	be9a43acc2f926b9433ab3f018b911b03896a924
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated\|COVID-19_Mild / Disease, condition lineage and cell class	IKZF3 HUWE1 USP9Y JAKMIP2 ZAP70 IVNS1ABP	6.96e-05	200	154	6	2281debd86e5d92e8fe0397aec9ef670800f7471
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T-T_CD8\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IKZF3 JAKMIP2 ZAP70 PTPN7 PREX1 CLEC2B	6.96e-05	200	154	6	02c4169a23e5aaa0d4bfc78b51ba19ce8157dc3e
ToppCell	(01)_Cycling_Basal_(homeostasis)-(1)_24hpi\|(01)_Cycling_Basal_(homeostasis) / shred by cell type and Timepoint	POLE2 DPEP2 EDDM3B DDX23	1.07e-04	71	154	4	6aa56b0daaeb5e0ae30619f9c6945c8e42899b27
ToppCell	tumor_Lung-T/NK_cells-CD8_low_T\|T/NK_cells / Location, Cell class and cell subclass	GIMAP4 IKZF3 EIF4EBP1 HSP90AA1 CLEC2B	1.35e-04	142	154	5	eaf08a0dbacc9ebbd54e377922e76d8ba854dcb8
ToppCell	COVID-19-kidney-Mito-rich_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADAMTSL1 PLVAP KALRN PDE10A GNA14	1.49e-04	145	154	5	afed661aef990edb8e7012ab67ace56443520c9f
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ERBB3 POLE2 MROH2B GPSM2 PREX1	1.75e-04	150	154	5	70ac8ae4b1683fb17278a8e4606f2fa0b94988c0
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell\|368C / Donor, Lineage, Cell class and subclass (all cells)	GIMAP4 IKZF3 ZAP70 PTPN7 SBF2	1.80e-04	151	154	5	512f7f37ddc8dfa1906f7fff92b571929236c9ea
ToppCell	facs-Brain_Myeloid-Cortex-3m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERBB3 SPATS2L PTPRK GPSM2 C3	1.92e-04	153	154	5	0ef7c45cdd854c79e527006034029767f8e108b2
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NOP58 SPATS2L TIAM1 IL1R2 USP15	1.97e-04	154	154	5	b16f3139ce50e70a6a2377b1da7d7877b4000ea1
ToppCell	PND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GIMAP4 IKZF3 ZAP70 PTPN7 PREX1	2.03e-04	155	154	5	4ae91bc7dbb9f713a1f110c17834b1d89f1b28db
ToppCell	PND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GIMAP4 IKZF3 ZAP70 PTPN7 PREX1	2.03e-04	155	154	5	fdcc8a475156329b3594d5ed22ba03538305327c
ToppCell	PND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GIMAP4 IKZF3 ZAP70 PTPN7 PREX1	2.03e-04	155	154	5	1fb49b48e34e740118908951e079ea2a9994ae4f
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GIMAP4 CYB5RL PLVAP ITGA5 TIAM1	2.36e-04	160	154	5	33050dc646762dc7e9dcc4a12c618e1ba1ce5a4d
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l44\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GIMAP4 ZAP70 PTPN7 KATNIP PREX1	2.36e-04	160	154	5	6b0faaa371650563f585722f5b2fb319e124ec38
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic-Mast_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	IKZF3 SLC28A3 CTPS2 TIAM1 CD274	2.36e-04	160	154	5	fe9970c160159b35f6599ed13c89cfb49264d554
ToppCell	droplet-Liver-Npc-21m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP4 IKZF3 ASB14 ZAP70 PTPN7	2.72e-04	165	154	5	6708beb0e8094f30cf5cd812e6a67a6db004a580
ToppCell	mild-Lymphocytic-CD4_T_cells_3\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	SHMT2 ZDBF2 SPATS2L TIAM1 USP15	2.79e-04	166	154	5	f8f8423423d72f0ea0266b59126abb27beb23094
ToppCell	368C-Myeloid-Monocyte-CD16+_Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	GPD2 IARS1 USP9Y MCM3AP MICAL3	2.87e-04	167	154	5	dbd2b9f2f4ba7be5fdf8318094e6b078cb1d1c43
ToppCell	facs-Lung-3m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l9\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IKZF3 ZAP70 CCDC148 PTPN7 PREX1	2.87e-04	167	154	5	38b1f052d663fa8f407c54bdd2060216f26feb0e
ToppCell	facs-Marrow-Granulocytes-24m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACE IL1R2 DPEP2 DHRS7 C3	2.95e-04	168	154	5	3611605114f6b668b44728d6563cd02389e106af
ToppCell	facs-Marrow-Granulocytes-24m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACE IL1R2 DPEP2 DHRS7 C3	3.03e-04	169	154	5	ee1969755180df58d32904e2bb4192da9373d03e
ToppCell	facs-Diaphragm-Limb_Muscle-18m-Endothelial-new-cluster\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLVAP STOX1 ACE GNA14 DEPDC7	3.12e-04	170	154	5	4fb4ce46e4fa2418238e264875209d7ebe844d82
ToppCell	facs-Liver-Non-hepatocytes-3m-Lymphocytic-mature_NK_T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IKZF3 DUOX2 ZAP70 PTPN7 RBPJ	3.20e-04	171	154	5	d322cc042a6f4b4aa8ef80ae977edbce9e266d48
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TSNAXIP1 MYH4 ASB14 C20orf96 TEKT1	3.20e-04	171	154	5	4f2a83d8091f1fd29542d2e5add57fd482e921b5
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell\|Adult / Lineage, Cell type, age group and donor	ADAMTSL1 MYLK KALRN SPEG MICAL3	3.29e-04	172	154	5	c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-SELL+_CD8_T\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LRRC63 GIMAP4 IKZF3 ZAP70 PTPN7	3.29e-04	172	154	5	10090b4b40f0f6f07a514e86811cadeecdf21670
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell\|Adult / Lineage, Cell type, age group and donor	MYLK KALRN SPEG ITGA5 MICAL3	3.38e-04	173	154	5	a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ADAMTSL1 MYLK KALRN SPEG ITGA5	3.38e-04	173	154	5	cb6389536195443633adb06e5f1b7483530773d1
ToppCell	LPS-antiTNF-Lymphocytic_NKT-iNKT/MAIT\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GIMAP4 IKZF3 ZAP70 PTPN7 PREX1	3.47e-04	174	154	5	61aa89b56ebda0eba1ba675d5f036992967f670f
ToppCell	P03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PLVAP MYLK ACE EIF4EBP1 ADAMTS17	3.56e-04	175	154	5	282f09bbdfa70d93b3f66591dcfb84c5ee0268c7
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRSAM1 ACE DPEP2 C3 NIN	3.56e-04	175	154	5	cf53a15bfb37b6019e7052ffdf594a9ac040900e
Drug	purealin	MYH1 MYH3 MYH4 MYLK MYO18B DYNC1H1	2.44e-06	58	152	6	CID006419303
Drug	AC1L1IZ2	MYH1 MYH3 MYH4 MYLK ZAP70 SOCS7 GH2 IGF1R MYO18B DYNC1H1 HSP90AA1	6.55e-06	304	152	11	CID000004795
Disease	autosomal dominant hyaline body myopathy (implicated_via_orthology)	MYH1 MYH3 MYH4	1.42e-05	10	147	3	DOID:0111269 (implicated_via_orthology)
Disease	distal arthrogryposis type 2B3 (implicated_via_orthology)	MYH1 MYH3 MYH4	1.42e-05	10	147	3	DOID:0111602 (implicated_via_orthology)
Disease	distal arthrogryposis type 1 (implicated_via_orthology)	MYH1 MYH3 MYH4	1.42e-05	10	147	3	DOID:0111596 (implicated_via_orthology)
Disease	dilated cardiomyopathy 1S (implicated_via_orthology)	MYH1 MYH3 MYH4	1.42e-05	10	147	3	DOID:0110454 (implicated_via_orthology)
Disease	congenital myopathy 6 (implicated_via_orthology)	MYH1 MYH3 MYH4	1.42e-05	10	147	3	DOID:0080719 (implicated_via_orthology)
Disease	inclusion body myositis (implicated_via_orthology)	MYH1 MYH3 MYH4	1.42e-05	10	147	3	DOID:3429 (implicated_via_orthology)
Disease	distal arthrogryposis type 2A (implicated_via_orthology)	MYH1 MYH3 MYH4	1.42e-05	10	147	3	DOID:0111605 (implicated_via_orthology)
Disease	familial hypertrophic cardiomyopathy (implicated_via_orthology)	MYH1 MYH3 MYH4	1.42e-05	10	147	3	DOID:0080326 (implicated_via_orthology)
Disease	Ovarian Mucinous Adenocarcinoma	ERBB3 MYLK SPEG WEE2	1.68e-05	31	147	4	C1335167
Disease	distal myopathy (implicated_via_orthology)	MYH1 MYH3 MYH4	2.58e-05	12	147	3	DOID:11720 (implicated_via_orthology)
Disease	myotonia congenita (implicated_via_orthology)	MYH1 MYH3 MYH4	2.58e-05	12	147	3	DOID:2106 (implicated_via_orthology)
Disease	restrictive cardiomyopathy (implicated_via_orthology)	MYH1 MYH3 MYH4	3.34e-05	13	147	3	DOID:397 (implicated_via_orthology)
Disease	distal arthrogryposis (implicated_via_orthology)	MYH1 MYH3 MYH4	5.28e-05	15	147	3	DOID:0050646 (implicated_via_orthology)
Disease	Gastric Adenocarcinoma	ERBB3 SPEG BMPR1A WEE2	7.52e-05	45	147	4	C0278701
Disease	Arthrogryposis	MYH3 VPS8 DYNC1H1	1.51e-04	21	147	3	C0003886
Disease	urate measurement	DNAJC13 MARK3 SHMT2 FNBP1L NOP58 CMIP IGF1R SPATS2L SBF2 ADAMTS17 HFM1 MYO18B FBXO34 HSP90AB3P	1.61e-04	895	147	14	EFO_0004531
Disease	marginal zone B-cell lymphoma, systemic lupus erythematosus	IKZF3 KALRN	2.44e-04	5	147	2	EFO_1000630, MONDO_0007915
Disease	isolated growth hormone deficiency type II (implicated_via_orthology)	GH1 GH2	2.44e-04	5	147	2	DOID:0060872 (implicated_via_orthology)
Disease	aortic valve disease (implicated_via_orthology)	ADAMTS19 RBPJ	3.65e-04	6	147	2	DOID:62 (implicated_via_orthology)
Disease	brain disease (implicated_via_orthology)	STIM2 TIAM1	3.65e-04	6	147	2	DOID:936 (implicated_via_orthology)
Disease	cardiomyopathy (implicated_via_orthology)	MYH1 MYH3 MYH4 ERBB3	4.43e-04	71	147	4	DOID:0050700 (implicated_via_orthology)
Disease	isolated growth hormone deficiency (implicated_via_orthology)	GH1 GH2	5.09e-04	7	147	2	DOID:0060870 (implicated_via_orthology)
Disease	eotaxin measurement	PRKRA GNA14 HFM1 MICAL3	6.97e-04	80	147	4	EFO_0008122
Disease	dilated cardiomyopathy (implicated_via_orthology)	MYH1 MYH3 MYH4 STIM2	6.97e-04	80	147	4	DOID:12930 (implicated_via_orthology)
Disease	dipeptidase 2 measurement	TSNAXIP1 DPEP2	1.08e-03	10	147	2	EFO_0801528
Disease	Charcot-Marie-Tooth disease	SBF2 MCM3AP DYNC1H1	1.21e-03	42	147	3	cv:C0007959
Disease	Weight Gain	STIM2 ACE GH1 INSIG2	1.72e-03	102	147	4	C0043094
Disease	myopathy (implicated_via_orthology)	MYH1 MYH3 MYH4	1.78e-03	48	147	3	DOID:423 (implicated_via_orthology)
Disease	HIV Infections	PSMA6 NUP88 EIF4EBP1 HSP90AA1	1.78e-03	103	147	4	C0019693
Disease	HIV Coinfection	PSMA6 NUP88 EIF4EBP1 HSP90AA1	1.78e-03	103	147	4	C4505456
Disease	amyotrophic lateral sclerosis (biomarker_via_orthology)	IGF1R C3	1.85e-03	13	147	2	DOID:332 (biomarker_via_orthology)
Disease	breast milk measurement	KALRN TRIML2 ZAP70 ULK4	1.98e-03	106	147	4	EFO_0009092
Disease	Abnormality of refraction	GPD2 SMG1 ADAMTSL1 DNAJC13 PLVAP BMPR1A IGF1R ZNF540 ULK4 NIN	2.07e-03	673	147	10	HP_0000539
Disease	congenital hypothyroidism (biomarker_via_orthology)	GH1 GH2	2.16e-03	14	147	2	DOID:0050328 (biomarker_via_orthology)
Disease	congenital hypothyroidism (implicated_via_orthology)	DUOX2 SLC26A7	2.16e-03	14	147	2	DOID:0050328 (implicated_via_orthology)
Disease	anemia (is_implicated_in)	ACE GH1	2.16e-03	14	147	2	DOID:2355 (is_implicated_in)
Disease	monoclonal gammopathy	ULK4 HFM1 PREX1	2.36e-03	53	147	3	EFO_0000203
Disease	lymphocyte count	GIMAP4 COX19 ERBB3 IKZF3 KALRN MARK3 NUP88 ANKLE2 GH1 CMIP FDFT1 MCM3AP C3 HFM1 MICAL3 PREX1	2.66e-03	1464	147	16	EFO_0004587
Disease	cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	ACACB SLC28A3 CMIP FDFT1 SBF2 HFM1	2.67e-03	276	147	6	EFO_0004612, EFO_0020943
Disease	Pre-Eclampsia	STOX1 ACE	2.83e-03	16	147	2	C0032914
Disease	Antibody Deficiency Syndrome	ZAP70 C3	3.19e-03	17	147	2	C0003257
Disease	glomerulonephritis (implicated_via_orthology)	ACE C3	3.19e-03	17	147	2	DOID:2921 (implicated_via_orthology)
Disease	lifestyle measurement, maximum cigarettes per day measurement	ADAMTSL1 COL19A1 CMIP C3	3.30e-03	122	147	4	EFO_0009264, EFO_0010724
Disease	Insulin Resistance	ACACB GH1 C3	3.37e-03	60	147	3	C0021655
Disease	polycystic ovary syndrome	ERBB3 IKZF3 CD274	3.37e-03	60	147	3	EFO_0000660
Disease	Insulin Sensitivity	ACACB GH1 C3	3.37e-03	60	147	3	C0920563
Disease	body fat distribution	ADAMTSL1 SLC28A3 CHCHD4 SLC26A7 ADAMTS17	3.49e-03	202	147	5	EFO_0004341
Disease	Allergic Reaction	MYLK IL1R2 CD274	3.87e-03	63	147	3	C1527304
Disease	Hypersensitivity	MYLK IL1R2 CD274	4.04e-03	64	147	3	C0020517
Disease	Calcium channel blocker use measurement	STIM2 ACE LRPPRC CMIP SBF2	4.36e-03	213	147	5	EFO_0009930
Disease	maximal midexpiratory flow rate	TUBGCP6 MICAL3	4.42e-03	20	147	2	EFO_0004313
Disease	selenium measurement, response to dietary selenium supplementation	TRIO GPR156	4.42e-03	20	147	2	EFO_0006331, EFO_0600021
Disease	COVID-19 (is_implicated_in)	ACE C3	4.86e-03	21	147	2	DOID:0080600 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
KLYERCEVVMGNLEI	ERBB3	51	P21860
REYKCDVLMRENEAL	EDDM3B	46	P56851
KEQYCIRKVRPSEEM	AKAP2	201	Q9Y2D5
DDDEAMLQKRIRYVV	ANKLE2	386	Q86XL3
EYQRLNEVRCKMESE	CCDC148	76	Q8NFR7
DFRIKQCTRVTMDQL	ACE	371	P12821
MSDRYLEQRISIKFC	GVQW3	1	Q3ZCU0
KVQVERMREVNSRCY	FBXO34	161	Q9NWN3
RIIYDRKFLMECRNS	EIF4EBP1	51	Q13541
STDVGKRMYEQLCDR	CMIP	611	Q8IY22
KRMYEQLCDRQRELK	CMIP	616	Q8IY22
KNTMILEICTRYRGD	C3	1381	P01024
EITVFREDLVNKMCR	POLE2	411	P56282
KLYEAIMREDCTTIE	ANKRD61	31	A6NGH8
RVMLDYVDQVRICSK	ASB14	496	A6NK59
VRVCQALMDYKVFEA	DEPDC7	96	Q96QD5
LCMDTSLDVYRKLIE	DHRS7	146	Q9Y394
VYCRVIREKNLCQDM	ADAMTS17	1056	Q8TE56
ITDVKLQDAGVYRCM	CD274	101	Q9NZQ7
VYCRVIREKNLCQDM	ADAMTS19	1171	Q8TE59
RIQDMKECPEYTVRQ	PTPN7	221	P35236
LIDYARMREVCDEVK	SHMT2	231	P34897
INPLCIEMYADKESR	ACACB	2211	O00763
YCLAVVEVVRRKMFI	RB1CC1	496	Q8TDY2
MLITVYCVRRDLSEV	DDI1	1	Q8WTU0
DLDKELNNYIMRCRE	NOP58	171	Q9Y2X3
LKCMQRFREIIDQFE	C20orf96	296	Q9NUD7
RQMLRKSREYDCQIL	JAKMIP2	756	Q96AA8
KSREYDCQILQERME	JAKMIP2	761	Q96AA8
ELTERECIKYMRQIS	MYLK	1556	Q15746
FCQKRVYVMERLSAE	MICAL3	766	Q7RTP6
IKEYACTAVDMISRR	GPD2	541	P43304
VRYRMEASCLELALE	GPSM2	16	P81274
IATYRKLLEGEECRM	KRT73	431	Q86Y46
EVLEKCMRLSYHQRI	NCBP1	451	Q09161
MTCARVRVYERKKED	MGA	1236	Q8IWI9
RVKQVCGDYLLSRMD	IVNS1ABP	116	Q9Y6Y0
MEQLVEKACFRDYQR	SBF2	1106	Q86WG5
SEEARKRLEYQMCLA	LRSAM1	11	Q6UWE0
KLYVRRVFIMDSCDE	HSP90AB3P	296	Q58FF7
QRMRADEIKDAIYVT	KATNIP	466	O60303
MSYCRQEGKDRIIFV	CHCHD4	1	Q8N4Q1
VRTKMVYCKIDQTQR	EIF3M	316	Q7L2H7
CPEKERYMRETRSQL	MCM3AP	641	O60318
EKFDLRTTMLYICER	DUOX2	1456	Q9NRD8
AEKYQTVIADICRRM	FDFT1	136	P37268
ENMECRDTTRYCEKV	ADAMTSL1	1726	Q8N6G6
CRKESKEYLECRMER	COX19	51	Q49B96
NPKLCVSEIYRMEEV	IGF1R	451	P08069
RYMAAIILSEKQCRD	PLVAP	131	Q9BX97
VSKNYRSVIRACMEE	NUP85	101	Q9BW27
VMKLACDDIRVNVVY	OR51E1	186	Q8TCB6
IRHSECIYRVTMEKL	PDE10A	421	Q9Y233
DRYRADLKAVREKCM	GPR153	301	Q6NV75
CKFALMNRETSERVV	KALRN	2191	O60229
RVIVMLYNKVCDIVS	NIPBL	1381	Q6KC79
CIIAMDRLTKDTYRV	CYB5RL	81	Q6IPT4
VMADKELYRACAVEV	NELFB	131	Q8WX92
LVVSKELRMYDERAQ	KLHL9	311	Q9P2J3
KTCMYRSEQEELRDK	KRI1	556	Q8N9T8
EKVTCERRYIPDAMN	LRPPRC	326	P42704
IEKDCAVYVGRMERV	TUBGCP6	636	Q96RT7
DLNRVLEEMRCQYET	KRT35	261	Q92764
CRGFLARVEYQKMVE	MYH1	796	P12882
QKMVERRESIFCIQY	MYH1	806	P12882
CEYISEMLLRNKSVR	NLRP4	796	Q96MN2
TQKRYEEVMVKCINA	LRRC63	561	Q05C16
VMKLACSDNRIDVIY	OR51A2	186	Q8NGJ7
VMKLACSDNRIDVIY	OR51A4	186	Q8NGJ6
LYTVAMSDRKCVELV	OR5J2	131	Q8NH18
SRCTYVVLDEADRMI	DDX23	541	Q9BUQ8
IGRQLAMYECKVIAE	INSIG2	206	Q9Y5U4
DTVYRVCDLIMTAIK	HUWE1	1456	Q7Z6Z7
DKYIQMLACRDTVES	HFM1	676	A2PYH4
IQNGAREDCREMKIY	ITGA5	576	P08648
REDCREMKIYLRNES	ITGA5	581	P08648
QEMDERRTIKLSECY	FNBP1L	216	Q5T0N5
YMDCNLIARRQTDEK	COL19A1	186	Q14993
VVVYCDRDTQLARLM	DCAKD	131	Q8WVC6
DPDRYQMVICRLQKE	EPM2AIP1	456	Q7L775
ETLEQQKRICEMAAY	COPA	1076	P53621
RYLGLMRCDKVNEVT	FBXL17	646	Q9UF56
VLQDCKRTLERAYQM	FBXL17	676	Q9UF56
EIDYTLCFRVRKMID	CACNA1I	1121	Q9P0X4
KMRYLEVSEPQDIEC	EIF3D	181	O15371
YDEISQLRLVCKRMD	FBXO28	81	Q9NVF7
VKMDRSLEYQPVECA	FOXRED1	271	Q96CU9
SYEDMREVVCVKRLR	BMPR1A	466	P36894
YIIGMLERCTDKLER	DNAJC13	896	O75165
MREIRKVLDANNCDY	MARK3	676	P27448
DREKCDTYQLIMEVR	DSC1	311	Q08554
KIDLEVRSLETCMYD	DYNC1H1	856	Q14204
EQIDLIRRMCASYSE	DPEP2	151	Q9H4A9
EKIVRLMSAECTYDL	GPR156	381	Q8NFN8
KVMKYERCQADQARL	HAUS6	316	Q7Z4H7
KMQLERYRVEYEALC	IFT20	101	Q8IY31
IKLYVRRVFIMDNCE	HSP90AA1	361	P07900
MLLTVYCVRRDLSEV	DDI2	1	Q5TDH0
EDLCRKSAIIETYVM	GRIPAP1	741	Q4V328
VINKEGEVMDVYRCD	IKZF3	441	Q9UKT9
VECKMNNIVSTRIYE	FABP9	116	Q0Z7S8
YMLVAKCLREEQETG	PYDC5	71	W6CW81
IDTACEILYERMKSL	DHX8	786	Q14562
VDLNKILEDMRCQYE	KRT36	256	O76013
MAEREGVVDIYNCVK	PTPRK	1101	Q15262
SYCREERKSLREMAE	NUP88	606	Q99567
MIRAMDTLRIQYVCE	GNA14	86	O95837
AVIGEYLCMRTELKE	SYS1	131	Q8N2H4
CTVSLTRYRVMIKEE	SPATS2L	231	Q9NUQ6
RVVRENKEGCYTNRM	GIMAP4	211	Q9NUV9
TCSEMQQKVELLRYE	NIN	1501	Q8N4C6
TVERCQELYRKYEMQ	SMG1	2676	Q96Q15
ELEDIMSKGVRLYCR	PREX1	506	Q8TCU6
VELCRDVAQYRLMKE	TEKT1	326	Q969V4
RKMMERRESIFCIQY	MYH4	806	Q9Y623
EFQKMVQRRESIFCI	MYH3	801	P11055
CLQQYKRRQEMADEI	VPS8	1261	Q8N3P4
KRRQEMADEIIVFSC	VPS8	1266	Q8N3P4
EDYRVCMDFNIIRKD	IARS1	331	P41252
EMQQKGCLERRYDTV	SLC28A3	76	Q9HAS3
DTNVLVYIKRRLAMC	ST7	291	Q9NRC1
LLIQTMCEKSYIEAR	MROH2B	376	Q7Z745
DKRVQTMNEFLTCIR	ABCC12	296	Q96J65
RGTTVYLCEKRIDMV	DIS3	526	Q9Y2L1
RNASYCDKMSIELRV	IL1R2	111	P27930
IEEMNFLRRYKCSSD	CLEC2B	76	Q92478
MDKVETFLRIVQCRS	GH2	196	P01242
VDMLCKRIADISQVY	PSMA6	111	P60900
ESEYSMRLRLLNEEC	TRIML2	106	Q8N7C3
RNMADRYERLQKICS	CTPS2	286	Q9NRF8
DCLRDAMVRDYVRQT	ZAP70	116	P43403
ECLDTTQRKLYRDVM	ZNF540	21	Q8NDQ6
CKRVFQEEDLRQIFM	XPO4	186	Q9C0E2
TERTYVKDLNCLMER	TIAM1	1051	Q13009
VCESEIRAYMRQVLE	SPEG	1691	Q15772
MDEINYAKEEACRLR	STIM2	291	Q9P246
MERVESQVLKRNECY	STOX1	786	Q6ZVD7
DDIRCKRYTLRKVMV	SPIRE1	311	Q08AE8
SRSMEYVQRQISKEC	SPRED1	206	Q7Z699
KPENILMCVDDAYVR	SRPK2	216	P78362
EAVAEKMLQYRRDTA	STARD5	11	Q9NSY2
LKELNIDMEVRSYDC	ZDBF2	731	Q9HCK1
LLRMCRYVKISTETE	USP15	611	Q9Y4E8
MDKVETFLRIVQCRS	GH1	196	P01241
MVRVLTVIKEYINEC	USP9Y	851	O00507
DRCQSVVEFIKRAIM	SOCS7	466	O14512
KDTERMYLCLSQERI	RBPJ	291	Q06330
IRYRENIASLMDKCF	VRK1	276	Q99986
REAEASRRCMELEKY	MYO18B	2041	Q8IUG5
SRRCMELEKYVEELA	MYO18B	2046	Q8IUG5
LQVEVDSSQKECRMY	MYH16	626	Q9H6N6
KREYTTICRLESFME	PRKRA	156	O75569
AMYLDCISDLRQKEI	ZNF862	276	O60290
RDASQCYVKMVCLRE	TXNRD2	441	Q9NNW7
CLDLEQRDLYRDVML	ZNF790	21	Q6PG37
TYRDICKNMVLAERC	TRAPPC8	491	Q9Y2L5
RCVLRETNMASRYEK	WEE2	196	P0C1S8
LDEAQRCLYRDVMLE	ZNF154	31	Q13106
VEVYMDCKGRSVDVL	SLC26A7	591	Q8TE54
NERILAMRAEEKYEI	TSNAXIP1	131	Q2TAA8
YLEMKDSEIRQIECD	THOC1	591	Q96FV9
IQTEKAYVRDLRECM	TRIO	1301	O75962
CQARLVMYIERDSRK	ULK4	771	Q96C45
MVQIRLEDRCYPVSK	KLHL42	6	Q9P2K6