Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cytoskeletal motor activity	KIF13B MYH2 MYH3 MYH6 MYH8 KIF4A KIFC2 DNAH17 KIF4B KIFC1 DNAH11	3.08e-10	118	130	11	GO:0003774
GeneOntologyMolecularFunction	ATP-dependent activity	KIF13B MYH2 MYH3 MYH6 MYH8 MCM8 SMC4 KIF4A TOR4A FANCM KIFC2 DDX11 ACSM4 DNAH17 KIF4B CARNS1 DHX34 HSPA2 ATP4A KIFC1 DNAH11	4.79e-10	614	130	21	GO:0140657
GeneOntologyMolecularFunction	ATP hydrolysis activity	KIF13B MYH3 MYH8 MCM8 SMC4 TOR4A FANCM KIFC2 DDX11 CARNS1 DHX34 HSPA2 ATP4A KIFC1 DNAH11	1.91e-07	441	130	15	GO:0016887
GeneOntologyMolecularFunction	microtubule motor activity	KIF13B KIF4A KIFC2 DNAH17 KIF4B KIFC1 DNAH11	3.59e-07	70	130	7	GO:0003777
GeneOntologyMolecularFunction	pyrophosphatase activity	KIF13B MYH3 MYH8 MCM8 CILP SMC4 TOR4A FANCM KIFC2 DDX11 CILP2 CARNS1 DHX34 HSPA2 ATP4A KIFC1 DNAH11	3.20e-05	839	130	17	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	KIF13B MYH3 MYH8 MCM8 CILP SMC4 TOR4A FANCM KIFC2 DDX11 CILP2 CARNS1 DHX34 HSPA2 ATP4A KIFC1 DNAH11	3.25e-05	840	130	17	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	KIF13B MYH3 MYH8 MCM8 CILP SMC4 TOR4A FANCM KIFC2 DDX11 CILP2 CARNS1 DHX34 HSPA2 ATP4A KIFC1 DNAH11	3.25e-05	840	130	17	GO:0016818
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	GLUD1 GLUD2	4.21e-05	2	130	2	GO:0016639
GeneOntologyMolecularFunction	glutamate dehydrogenase [NAD(P)+] activity	GLUD1 GLUD2	4.21e-05	2	130	2	GO:0004353
GeneOntologyMolecularFunction	glutamate dehydrogenase (NAD+) activity	GLUD1 GLUD2	4.21e-05	2	130	2	GO:0004352
GeneOntologyMolecularFunction	glutamate dehydrogenase (NADP+) activity	GLUD1 GLUD2	4.21e-05	2	130	2	GO:0004354
GeneOntologyMolecularFunction	microfilament motor activity	MYH2 MYH3 MYH6 MYH8	1.07e-04	38	130	4	GO:0000146
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	KIF13B MYH3 MYH8 MCM8 SMC4 TOR4A FANCM KIFC2 DDX11 CARNS1 DHX34 HSPA2 ATP4A KIFC1 DNAH11	1.59e-04	775	130	15	GO:0017111
GeneOntologyMolecularFunction	NAD+ binding	SIRT6 GLUD1 GLUD2	2.83e-04	20	130	3	GO:0070403
GeneOntologyMolecularFunction	alkaline phosphatase activity	CILP CILP2	6.20e-04	6	130	2	GO:0004035
GeneOntologyMolecularFunction	L-leucine binding	GLUD1 GLUD2	8.65e-04	7	130	2	GO:0070728
GeneOntologyMolecularFunction	phosphoric ester hydrolase activity	MYH3 MYH6 MYH8 CILP PPP1CB FAN1 CILP2 PTPRB MPPED2	9.69e-04	386	130	9	GO:0042578
GeneOntologyMolecularFunction	amino acid binding	CAD GLUD1 GLUD2 TAT	1.32e-03	73	130	4	GO:0016597
GeneOntologyMolecularFunction	dinucleotide phosphatase activity	CILP CILP2	1.47e-03	9	130	2	GO:0004551
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	MCM8 FANCM HMCES FAN1 DDX11 ERVK-8 NEIL3	1.66e-03	262	130	7	GO:0140097
GeneOntologyMolecularFunction	iron-sulfur cluster binding	KIF4A DDX11 FECH KIF4B	1.69e-03	78	130	4	GO:0051536
GeneOntologyMolecularFunction	single-stranded DNA binding	MCM8 SMC4 HMCES DDX11 NEIL3	1.85e-03	134	130	5	GO:0003697
GeneOntologyMolecularFunction	metal cluster binding	KIF4A DDX11 FECH KIF4B	2.12e-03	83	130	4	GO:0051540
GeneOntologyMolecularFunction	myosin phosphatase activity	MYH3 MYH6 MYH8 PPP1CB	2.31e-03	85	130	4	GO:0017018
GeneOntologyBiologicalProcess	muscle filament sliding	MYH2 MYH3 MYH6 MYH8	2.01e-06	15	131	4	GO:0030049
GeneOntologyBiologicalProcess	actin-myosin filament sliding	MYH2 MYH3 MYH6 MYH8	4.44e-06	18	131	4	GO:0033275
GeneOntologyBiologicalProcess	interstrand cross-link repair	MCM8 FANCM HMCES FAN1 NEIL3	6.74e-06	42	131	5	GO:0036297
GeneOntologyCellularComponent	muscle myosin complex	MYH2 MYH3 MYH6 MYH8	2.45e-06	16	130	4	GO:0005859
GeneOntologyCellularComponent	myosin filament	MYH2 MYH3 MYH6 MYH8	1.63e-05	25	130	4	GO:0032982
GeneOntologyCellularComponent	myosin II complex	MYH2 MYH3 MYH6 MYH8	2.60e-05	28	130	4	GO:0016460
GeneOntologyCellularComponent	microtubule associated complex	KIF13B KIF4A KIFC2 DNAH17 KIF4B KIFC1 DNAH11	6.74e-05	161	130	7	GO:0005875
GeneOntologyCellularComponent	myosin complex	MYH2 MYH3 MYH6 MYH8	4.99e-04	59	130	4	GO:0016459
Domain	Myosin_N	MYH2 MYH3 MYH6 MYH8	2.47e-06	15	125	4	PF02736
Domain	Myosin_N	MYH2 MYH3 MYH6 MYH8	2.47e-06	15	125	4	IPR004009
Domain	Myosin_tail_1	MYH2 MYH3 MYH6 MYH8	5.44e-06	18	125	4	PF01576
Domain	Myosin_tail	MYH2 MYH3 MYH6 MYH8	5.44e-06	18	125	4	IPR002928
Domain	WxxW_domain	CILP CILP2 MUC5AC	5.77e-06	6	125	3	IPR025155
Domain	Mucin2_WxxW	CILP CILP2 MUC5AC	5.77e-06	6	125	3	PF13330
Domain	Myosin-like_IQ_dom	MYH2 MYH3 MYH6 MYH8	6.86e-06	19	125	4	IPR027401
Domain	-	MYH2 MYH3 MYH6 MYH8	6.86e-06	19	125	4	4.10.270.10
Domain	Kinesin_motor_CS	KIF13B KIF4A KIFC2 KIF4B KIFC1	7.66e-06	41	125	5	IPR019821
Domain	Kinesin-like_fam	KIF13B KIF4A KIFC2 KIF4B KIFC1	9.73e-06	43	125	5	IPR027640
Domain	-	KIF13B KIF4A KIFC2 KIF4B KIFC1	1.09e-05	44	125	5	3.40.850.10
Domain	Kinesin	KIF13B KIF4A KIFC2 KIF4B KIFC1	1.09e-05	44	125	5	PF00225
Domain	KISc	KIF13B KIF4A KIFC2 KIF4B KIFC1	1.09e-05	44	125	5	SM00129
Domain	KINESIN_MOTOR_1	KIF13B KIF4A KIFC2 KIF4B KIFC1	1.09e-05	44	125	5	PS00411
Domain	Kinesin_motor_dom	KIF13B KIF4A KIFC2 KIF4B KIFC1	1.09e-05	44	125	5	IPR001752
Domain	KINESIN_MOTOR_2	KIF13B KIF4A KIFC2 KIF4B KIFC1	1.09e-05	44	125	5	PS50067
Domain	P-loop_NTPase	MAGI1 KIF13B MYH2 MYH3 MYH6 MYH8 MCM8 SMC4 KIF4A TOR4A FANCM KIFC2 URGCP DDX11 KIF4B DHX34 KIFC1 DNAH11	1.38e-05	848	125	18	IPR027417
Domain	ELFV_dehydrog_N	GLUD1 GLUD2	4.44e-05	2	125	2	PF02812
Domain	Glu/Leu/Phe/Val_DH_C	GLUD1 GLUD2	4.44e-05	2	125	2	IPR006096
Domain	Glu/Leu/Phe/Val_DH_dimer_dom	GLUD1 GLUD2	4.44e-05	2	125	2	IPR006097
Domain	Glu/Leu/Phe/Val_DH	GLUD1 GLUD2	4.44e-05	2	125	2	IPR006095
Domain	ELFV_dehydrog	GLUD1 GLUD2	4.44e-05	2	125	2	PF00208
Domain	NAD_bind_Glu_DH	GLUD1 GLUD2	4.44e-05	2	125	2	IPR033922
Domain	GLFV_DEHYDROGENASE	GLUD1 GLUD2	4.44e-05	2	125	2	PS00074
Domain	ELFV_dehydrog	GLUD1 GLUD2	4.44e-05	2	125	2	SM00839
Domain	Glu/Leu/Phe/Val_DH_AS	GLUD1 GLUD2	4.44e-05	2	125	2	IPR033524
Domain	Myosin_head_motor_dom	MYH2 MYH3 MYH6 MYH8	1.18e-04	38	125	4	IPR001609
Domain	MYOSIN_MOTOR	MYH2 MYH3 MYH6 MYH8	1.18e-04	38	125	4	PS51456
Domain	Myosin_head	MYH2 MYH3 MYH6 MYH8	1.18e-04	38	125	4	PF00063
Domain	MYSc	MYH2 MYH3 MYH6 MYH8	1.18e-04	38	125	4	SM00242
Domain	RCC1	RCBTB1 HERC1 HERC4	3.07e-04	20	125	3	PF00415
Domain	RCC1_1	RCBTB1 HERC1 HERC4	3.56e-04	21	125	3	PS00625
Domain	RCC1_2	RCBTB1 HERC1 HERC4	3.56e-04	21	125	3	PS00626
Domain	RCC1_3	RCBTB1 HERC1 HERC4	3.56e-04	21	125	3	PS50012
Domain	-	RCBTB1 HERC1 HERC4	4.11e-04	22	125	3	2.130.10.30
Domain	Reg_chr_condens	RCBTB1 HERC1 HERC4	4.11e-04	22	125	3	IPR000408
Domain	RCC1/BLIP-II	RCBTB1 HERC1 HERC4	4.70e-04	23	125	3	IPR009091
Domain	HECT	HERC1 HERC4 SMURF2	7.61e-04	27	125	3	PF00632
Domain	HECTc	HERC1 HERC4 SMURF2	7.61e-04	27	125	3	SM00119
Domain	HECT_dom	HERC1 HERC4 SMURF2	7.61e-04	27	125	3	IPR000569
Domain	HECT	HERC1 HERC4 SMURF2	7.61e-04	27	125	3	PS50237
Domain	TSP_1	ADAMTSL1 CILP ADAMTSL3 CILP2	8.40e-04	63	125	4	PF00090
Domain	Hirudin/antistatin	ZFAND4 MUC5AC	9.13e-04	7	125	2	IPR011061
Domain	TSP1	ADAMTSL1 CILP ADAMTSL3 CILP2	9.44e-04	65	125	4	SM00209
Domain	TSP1_rpt	ADAMTSL1 CILP ADAMTSL3 CILP2	9.44e-04	65	125	4	IPR000884
Domain	TSP1	ADAMTSL1 CILP ADAMTSL3 CILP2	9.44e-04	65	125	4	PS50092
Domain	Semap_dom	SEMA4D SEMA4A PLXNA1	1.15e-03	31	125	3	IPR001627
Domain	SEMA	SEMA4D SEMA4A PLXNA1	1.15e-03	31	125	3	PS51004
Domain	Sema	SEMA4D SEMA4A PLXNA1	1.15e-03	31	125	3	SM00630
Domain	Sema	SEMA4D SEMA4A PLXNA1	1.15e-03	31	125	3	PF01403
Domain	Plexin_repeat	SEMA4D SEMA4A PLXNA1	1.26e-03	32	125	3	IPR002165
Domain	PSI	SEMA4D SEMA4A PLXNA1	1.26e-03	32	125	3	PF01437
Domain	IQ	MYH2 MYH3 MYH6 MYH8	1.31e-03	71	125	4	PF00612
Domain	DNA/RNA_helicase_DEAH_CS	FANCM DDX11 DHX34	1.64e-03	35	125	3	IPR002464
Domain	DEAH_ATP_HELICASE	FANCM DDX11 DHX34	2.08e-03	38	125	3	PS00690
Domain	IQ	MYH2 MYH3 MYH6 MYH8	2.14e-03	81	125	4	SM00015
Domain	IQ_motif_EF-hand-BS	MYH2 MYH3 MYH6 MYH8	3.14e-03	90	125	4	IPR000048
Domain	PSI	SEMA4D SEMA4A PLXNA1	3.17e-03	44	125	3	IPR016201
Domain	IQ	MYH2 MYH3 MYH6 MYH8	3.53e-03	93	125	4	PS50096
Domain	PSI	SEMA4D SEMA4A PLXNA1	3.60e-03	46	125	3	SM00423
Domain	ATP_GRASP	CAD CARNS1	3.84e-03	14	125	2	PS50975
Domain	PLAC	ADAMTSL1 ADAMTSL3	3.84e-03	14	125	2	PF08686
Domain	ATP-grasp	CAD CARNS1	3.84e-03	14	125	2	IPR011761
Domain	CarboxyPept-like_regulatory	CILP CILP2	5.66e-03	17	125	2	IPR008969
Domain	CTCK_1	SLIT1 MUC5AC	6.34e-03	18	125	2	PS01185
Domain	-	CAD CARNS1	6.34e-03	18	125	2	3.30.470.20
Pathway	KEGG_TIGHT_JUNCTION	MAGI1 MYH2 MYH3 MYH6 MYH8 PPP2R2C PRKCG	5.38e-05	132	104	7	M11355
Pathway	REACTOME_KINESINS	KIF13B KIF4A KIFC2 KIF4B KIFC1	6.13e-05	57	104	5	MM15714
Pathway	REACTOME_KINESINS	KIF13B KIF4A KIFC2 KIF4B KIFC1	8.50e-05	61	104	5	M977
Pathway	REACTOME_OTHER_SEMAPHORIN_INTERACTIONS	SEMA4D SEMA4A PLXNA1	1.34e-04	14	104	3	MM15047
Pubmed	Diversity in transcriptional start site selection and alternative splicing affects the 5'-UTR of mouse striated muscle myosin transcripts.	MYH2 MYH3 MYH6 MYH8	7.31e-09	7	134	4	16819597
Pubmed	The inhibition of differentiation caused by TGFbeta in fetal myoblasts is dependent upon selective expression of PKCtheta: a possible molecular basis for myoblast diversification during limb histogenesis.	MYH2 MYH3 MYH8 PRKCG	1.47e-07	13	134	4	8948582
Pubmed	Evaluation of embryonic and perinatal myosin gene mutations and the etiology of congenital idiopathic clubfoot.	MYH2 MYH3 MYH8	2.23e-07	4	134	3	20357587
Pubmed	Developmental pattern of mouse skeletal myosin heavy chain gene transcripts in vivo and in vitro.	MYH2 MYH3 MYH8	5.56e-07	5	134	3	3829126
Pubmed	Sequential accumulation of mRNAs encoding different myosin heavy chain isoforms during skeletal muscle development in vivo detected with a recombinant plasmid identified as coding for an adult fast myosin heavy chain from mouse skeletal muscle.	MYH2 MYH3 MYH8	5.56e-07	5	134	3	6196357
Pubmed	NK-2 class homeobox genes and pharyngeal/oral patterning: Nkx2-3 is required for salivary gland and tooth morphogenesis.	NKX2-6 NKX2-5 PAX9	5.56e-07	5	134	3	12141427
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	MYH6 CAD SRPK2 YJEFN3 SHANK3 PDHX PPP1CB PPP2R2C EIF2S1 GLUD1 GLUD2 PRKCG LRRC7 EIF3C RPL13A LYZ HSPA2 CPSF7 DNPEP DNAH11	6.24e-07	1431	134	20	37142655
Pubmed	Distinct myogenic programs of embryonic and fetal mouse muscle cells: expression of the perinatal myosin heavy chain isoform in vitro.	MYH2 MYH3 MYH8	1.11e-06	6	134	3	1728586
Pubmed	Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved.	MYH2 MYH3 MYH8	1.11e-06	6	134	3	10077619
Pubmed	Spatial and temporal changes in myosin heavy chain gene expression in skeletal muscle development.	MYH2 MYH3 MYH8	1.11e-06	6	134	3	10588881
Pubmed	A new role for the calcineurin/NFAT pathway in neonatal myosin heavy chain expression via the NFATc2/MyoD complex during mouse myogenesis.	MYH2 MYH3 MYH6 MYH8	1.46e-06	22	134	4	24301466
Pubmed	NKX2 gene expression in neuroectoderm but not in mesendodermally derived structures depends on sonic hedgehog in mouse embryos.	NKX2-6 NKX2-5 NKX2-2	1.94e-06	7	134	3	10603087
Pubmed	A fast Myosin super enhancer dictates muscle fiber phenotype through competitive interactions with Myosin genes.	MYH2 MYH3 MYH8	1.94e-06	7	134	3	35210422
Pubmed	Phenotypic characterization of the murine Nkx2.6 homeobox gene by gene targeting.	NKX2-6 NKX2-5 PAX9	1.94e-06	7	134	3	10733590
Pubmed	Genes for skeletal muscle myosin heavy chains are clustered and are not located on the same mouse chromosome as a cardiac myosin heavy chain gene.	MYH3 MYH6 MYH8	3.09e-06	8	134	3	3864153
Pubmed	Sequence and chromosomal assignment of human BAPX1, a bagpipe-related gene, to 4p16.1: a candidate gene for skeletal dysplasia.	NKX2-6 NKX2-5 NKX2-2	4.62e-06	9	134	3	9344671
Pubmed	Centronuclear myopathy in mice lacking a novel muscle-specific protein kinase transcriptionally regulated by MEF2.	MYH3 MYH8 CILP SRPK2	6.11e-06	31	134	4	16140986
Pubmed	Nkx2.5 and Nkx2.6, homologs of Drosophila tinman, are required for development of the pharynx.	NKX2-6 NKX2-5 PAX9	6.58e-06	10	134	3	11390666
Pubmed	The homeodomain protein vax1 is required for axon guidance and major tract formation in the developing forebrain.	EPHB3 SLIT1 NKX2-2	6.58e-06	10	134	3	10601035
Pubmed	Acceleration of somitic myogenesis in embryos of myogenin promoter-MRF4 transgenic mice.	MYH2 MYH3 MYH8	6.58e-06	10	134	3	8950513
Pubmed	Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference.	KIF4A KIF4B KIFC1	9.02e-06	11	134	3	15843429
Pubmed	Dysregulation of nuclear receptor COUP-TFII impairs skeletal muscle development.	MYH2 MYH3 MYH8	1.20e-05	12	134	3	28600496
Pubmed	All kinesin superfamily protein, KIF, genes in mouse and human.	KIF13B KIF4A KIF4B KIFC1	1.26e-05	37	134	4	11416179
Pubmed	Semaphorins 4A and 4D in chronic inflammatory diseases.	SEMA4D SEMA4A	1.47e-05	2	134	2	27554682
Pubmed	KIF4 regulates neuronal morphology and seizure susceptibility via the PARP1 signaling pathway.	KIF4A KIF4B	1.47e-05	2	134	2	36482480
Pubmed	Common arterial trunk associated with a homeodomain mutation of NKX2.6.	NKX2-6 NKX2-5	1.47e-05	2	134	2	15649947
Pubmed	Glutamate Delta-1 Receptor Regulates Inhibitory Neurotransmission in the Nucleus Accumbens Core and Anxiety-Like Behaviors.	GLUD1 GLUD2	1.47e-05	2	134	2	34173171
Pubmed	Glutamate dehydrogenase is essential to sustain neuronal oxidative energy metabolism during stimulation.	GLUD1 GLUD2	1.47e-05	2	134	2	28621566
Pubmed	GluD1 knockout mice with a pure C57BL/6N background show impaired fear memory, social interaction, and enhanced depressive-like behavior.	GLUD1 GLUD2	1.47e-05	2	134	2	32078638
Pubmed	Development of mice with brain-specific deletion of floxed glud1 (glutamate dehydrogenase 1) using cre recombinase driven by the nestin promoter.	GLUD1 GLUD2	1.47e-05	2	134	2	23595828
Pubmed	The multiple functions of kinesin-4 family motor protein KIF4 and its clinical potential.	KIF4A KIF4B	1.47e-05	2	134	2	30081192
Pubmed	Interaction between glutamate dehydrogenase (GDH) and L-leucine catabolic enzymes: intersecting metabolic pathways.	GLUD1 GLUD2	1.47e-05	2	134	2	21621574
Pubmed	Chromokinesin Kif4 promotes proper anaphase in mouse oocyte meiosis.	KIF4A KIF4B	1.47e-05	2	134	2	31067151
Pubmed	Identification of the molecular dysfunction caused by glutamate dehydrogenase S445L mutation responsible for hyperinsulinism/hyperammonemia.	GLUD1 GLUD2	1.47e-05	2	134	2	28911206
Pubmed	Delineation of glutamate pathways and secretory responses in pancreatic islets with β-cell-specific abrogation of the glutamate dehydrogenase.	GLUD1 GLUD2	1.47e-05	2	134	2	22875990
Pubmed	Molecular basis of human glutamate dehydrogenase regulation under changing energy demands.	GLUD1 GLUD2	1.47e-05	2	134	2	15578726
Pubmed	Important role of Ser443 in different thermal stability of human glutamate dehydrogenase isozymes.	GLUD1 GLUD2	1.47e-05	2	134	2	15044002
Pubmed	Induction of excitatory and inhibitory presynaptic differentiation by GluD1.	GLUD1 GLUD2	1.47e-05	2	134	2	22138648
Pubmed	Cellular motor protein KIF-4 associates with retroviral Gag.	KIF4A KIF4B	1.47e-05	2	134	2	10559369
Pubmed	Glutamate Dehydrogenase Is Important for Ammonia Fixation and Amino Acid Homeostasis in Brain During Hyperammonemia.	GLUD1 GLUD2	1.47e-05	2	134	2	34220417
Pubmed	Expression of human GLUD1 and GLUD2 glutamate dehydrogenases in steroid producing tissues.	GLUD1 GLUD2	1.47e-05	2	134	2	26241911
Pubmed	Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants.	NKX2-6 NKX2-5	1.47e-05	2	134	2	7904557
Pubmed	Differential levels of glutamate dehydrogenase 1 (GLUD1) in Balb/c and C57BL/6 mice and the effects of overexpression of the Glud1 gene on glutamate release in striatum.	GLUD1 GLUD2	1.47e-05	2	134	2	21446915
Pubmed	KIF4 regulates midzone length during cytokinesis.	KIF4A KIF4B	1.47e-05	2	134	2	21565503
Pubmed	Assignment of cardiac homeobox gene CSX to human chromosome 5q34.	NKX2-6 NKX2-5	1.47e-05	2	134	2	7665173
Pubmed	Cartilage intermediate layer protein 2 (CILP-2) is expressed in articular and meniscal cartilage and down-regulated in experimental osteoarthritis.	CILP CILP2	1.47e-05	2	134	2	21880736
Pubmed	GluD1 binds GABA and controls inhibitory plasticity.	GLUD1 GLUD2	1.47e-05	2	134	2	38060673
Pubmed	A novel microtubule-based motor protein (KIF4) for organelle transports, whose expression is regulated developmentally.	KIF4A KIF4B	1.47e-05	2	134	2	7929562
Pubmed	Gene expression patterns in the hippocampus during the development and aging of Glud1 (Glutamate Dehydrogenase 1) transgenic and wild type mice.	GLUD1 GLUD2	1.47e-05	2	134	2	24593767
Pubmed	Potentiation of neuronal activity by tonic GluD1 current in brain slices.	GLUD1 GLUD2	1.47e-05	2	134	2	37154294
Pubmed	Deletion of glutamate dehydrogenase 1 (Glud1) in the central nervous system affects glutamate handling without altering synaptic transmission.	GLUD1 GLUD2	1.47e-05	2	134	2	22924626
Pubmed	Nerve tissue-specific (GLUD2) and housekeeping (GLUD1) human glutamate dehydrogenases are regulated by distinct allosteric mechanisms: implications for biologic function.	GLUD1 GLUD2	1.47e-05	2	134	2	11032875
Pubmed	Localization of Human Glutamate Dehydrogenases Provides Insights into Their Metabolic Role and Their Involvement in Disease Processes.	GLUD1 GLUD2	1.47e-05	2	134	2	29943084
Pubmed	Glutamate dehydrogenase deficiency disrupts glutamate homeostasis in hippocampus and prefrontal cortex and impairs recognition memory.	GLUD1 GLUD2	1.47e-05	2	134	2	31898404
Pubmed	Birth and adaptive evolution of a hominoid gene that supports high neurotransmitter flux.	GLUD1 GLUD2	1.47e-05	2	134	2	15378063
Pubmed	Widening Spectrum of Cellular and Subcellular Expression of Human GLUD1 and GLUD2 Glutamate Dehydrogenases Suggests Novel Functions.	GLUD1 GLUD2	1.47e-05	2	134	2	27422263
Pubmed	Critical role of the cysteine 323 residue in the catalytic activity of human glutamate dehydrogenase isozymes.	GLUD1 GLUD2	1.47e-05	2	134	2	15750346
Pubmed	Molecular cloning, structure and expression analysis of a full-length mouse brain glutamate dehydrogenase cDNA.	GLUD1 GLUD2	1.47e-05	2	134	2	1711373
Pubmed	Whole genome expression microarray reveals novel roles for Kif4 in monocyte/macrophage cells.	KIF4A KIF4B	1.47e-05	2	134	2	31486502
Pubmed	Transcriptomic responses in mouse brain exposed to chronic excess of the neurotransmitter glutamate.	GLUD1 GLUD2	1.47e-05	2	134	2	20529287
Pubmed	Determination of glutamate dehydrogenase activity and its kinetics in mouse tissues using metabolic mapping (quantitative enzyme histochemistry).	GLUD1 GLUD2	1.47e-05	2	134	2	25124006
Pubmed	Assignment of the kinesin family member 4 genes (KIF4A and KIF4B) to human chromosome bands Xq13.1 and 5q33.1 by in situ hybridization.	KIF4A KIF4B	1.47e-05	2	134	2	10773663
Pubmed	NKX2.5/NKX2.6 mutations are not a common cause of isolated type 1 truncus arteriosus in a small cohort of multiethnic cases.	NKX2-6 NKX2-5	1.47e-05	2	134	2	18939937
Pubmed	Unexpected histone H3 tail-clipping activity of glutamate dehydrogenase.	GLUD1 GLUD2	1.47e-05	2	134	2	23673664
Pubmed	Lack of evidence for direct ligand-gated ion channel activity of GluD receptors.	GLUD1 GLUD2	1.47e-05	2	134	2	39052831
Pubmed	Missense Pathogenic variants in KIF4A Affect Dental Morphogenesis Resulting in X-linked Taurodontism, Microdontia and Dens-Invaginatus.	KIF4A KIF4B	1.47e-05	2	134	2	31616463
Pubmed	Metabolism changes during aging in the hippocampus and striatum of glud1 (glutamate dehydrogenase 1) transgenic mice.	GLUD1 GLUD2	1.47e-05	2	134	2	24442550
Pubmed	Kif4 regulates the expression of VEGFR1 through the PI3K/Akt signaling pathway in RAW264.7 monocytes/macrophages.	KIF4A KIF4B	1.47e-05	2	134	2	28350061
Pubmed	The Amplifying Pathway of the β-Cell Contributes to Diet-induced Obesity.	GLUD1 GLUD2	1.47e-05	2	134	2	27137930
Pubmed	GDH-Dependent Glutamate Oxidation in the Brain Dictates Peripheral Energy Substrate Distribution.	GLUD1 GLUD2	1.47e-05	2	134	2	26440896
Pubmed	Study of structure-function relationships in human glutamate dehydrogenases reveals novel molecular mechanisms for the regulation of the nerve tissue-specific (GLUD2) isoenzyme.	GLUD1 GLUD2	1.47e-05	2	134	2	12742085
Pubmed	Kif4 interacts with EB1 and stabilizes microtubules downstream of Rho-mDia in migrating fibroblasts.	KIF4A KIF4B	1.47e-05	2	134	2	24658398
Pubmed	Loss of Sirt6 in adipocytes impairs the ability of adipose tissue to adapt to intermittent fasting.	SIRT6 LYZ	1.47e-05	2	134	2	34493807
Pubmed	Mitochondrial targeting adaptation of the hominoid-specific glutamate dehydrogenase driven by positive Darwinian selection.	GLUD1 GLUD2	1.47e-05	2	134	2	18688271
Pubmed	The complex regulation of human glud1 and glud2 glutamate dehydrogenases and its implications in nerve tissue biology.	GLUD1 GLUD2	1.47e-05	2	134	2	22658952
Pubmed	Increases in anterograde axoplasmic transport in neurons of the hyper-glutamatergic, glutamate dehydrogenase 1 (Glud1) transgenic mouse: Effects of glutamate receptors on transport.	GLUD1 GLUD2	1.47e-05	2	134	2	38124277
Pubmed	Deletion of glutamate dehydrogenase in beta-cells abolishes part of the insulin secretory response not required for glucose homeostasis.	GLUD1 GLUD2	1.47e-05	2	134	2	19015267
Pubmed	Structural basis for the ATP-induced isomerization of kinesin.	KIF4A KIF4B	1.47e-05	2	134	2	23500491
Pubmed	Human GLUD1 and GLUD2 glutamate dehydrogenase localize to mitochondria and endoplasmic reticulum.	GLUD1 GLUD2	1.47e-05	2	134	2	19448744
Pubmed	SIRT6-mediated transcriptional suppression of Txnip is critical for pancreatic beta cell function and survival in mice.	SIRT6 TXNIP	1.47e-05	2	134	2	29322219
Pubmed	Single amino acid substitution (G456A) in the vicinity of the GTP binding domain of human housekeeping glutamate dehydrogenase markedly attenuates GTP inhibition and abolishes the cooperative behavior of the enzyme.	GLUD1 GLUD2	1.47e-05	2	134	2	11950837
Pubmed	Binding of murine leukemia virus Gag polyproteins to KIF4, a microtubule-based motor protein.	KIF4A KIF4B	1.47e-05	2	134	2	9658142
Pubmed	Contractile protein gene expression in primary myotubes of embryonic mouse hindlimb muscles.	MYH2 MYH3 MYH8	1.55e-05	13	134	3	8404542
Pubmed	Tulp3 is a critical repressor of mouse hedgehog signaling.	TULP3 NKX2-2 PAX9	1.55e-05	13	134	3	19334287
Pubmed	An extraribosomal function of ribosomal protein L13a in macrophages resolves inflammation.	CCL18 RPL13A LYZ	1.55e-05	13	134	3	23460747
Pubmed	Identification of downstream genetic pathways of Tbx1 in the second heart field.	MYH6 NKX2-6 NKX2-5	1.55e-05	13	134	3	18328475
Pubmed	Defective excitation-contraction coupling is partially responsible for impaired contractility in hindlimb muscles of Stac3 knockout mice.	MYH2 MYH3 MYH8	1.97e-05	14	134	3	27184118
Pubmed	Loss of Prox1 in striated muscle causes slow to fast skeletal muscle fiber conversion and dilated cardiomyopathy.	MYH2 MYH6 NKX2-5	1.97e-05	14	134	3	24938781
Pubmed	DelK32-lamin A/C has abnormal location and induces incomplete tissue maturation and severe metabolic defects leading to premature death.	MYH3 MYH6 MYH8	3.02e-05	16	134	3	22090424
Pubmed	Slow and fast fiber isoform gene expression is systematically altered in skeletal muscle of the Sox6 mutant, p100H.	MYH2 MYH3 MYH8	3.66e-05	17	134	3	16124007
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	MAGI1 MYH2 TNFRSF14 SMC4 KIF4A SRPK2 PPP1CB SH3BP4 EIF2S1 DSTYK BOP1 LRRC7 ACOT2 HERC1 LYZ DNPEP	3.69e-05	1284	134	16	17353931
Pubmed	The role of floor plate contact in the elaboration of contralateral commissural projections within the embryonic mouse spinal cord.	EPHB3 SLIT1 NKX2-2	4.37e-05	18	134	3	16854408
Pubmed	Progression of chronic liver inflammation and fibrosis driven by activation of c-JUN signaling in Sirt6 mutant mice.	SIRT6 LYZ	4.41e-05	3	134	2	23076146
Pubmed	The structure of apo human glutamate dehydrogenase details subunit communication and allostery.	GLUD1 GLUD2	4.41e-05	3	134	2	12054821
Pubmed	Semaphorin 4A, 4C, and 4D: Function comparison in the autoimmunity, allergy, and cancer.	SEMA4D SEMA4A	4.41e-05	3	134	2	32244055
Pubmed	Trans-Synaptic Signaling through the Glutamate Receptor Delta-1 Mediates Inhibitory Synapse Formation in Cortical Pyramidal Neurons.	GLUD1 GLUD2	4.41e-05	3	134	2	31704028
Pubmed	Mouse embryonic stem cells express the cardiac myosin heavy chain genes during development in vitro.	MYH3 MYH6	4.41e-05	3	134	2	1694848
Pubmed	Puerarin alleviates noise-induced hearing loss via affecting PKCγ and GABAB receptor expression.	PRKCG GABBR1	4.41e-05	3	134	2	25592416
Pubmed	Tumor formation via loss of a molecular motor protein.	KIF4A KIF4B	4.41e-05	3	134	2	16890532
Pubmed	KIF4 mediates anterograde translocation and positioning of ribosomal constituents to axons.	KIF4A KIF4B	4.41e-05	3	134	2	19158085
Interaction	ACTN2 interactions	MYH2 MYH3 MYH6 MYH8 SHANK3 TULP3 PPP1CB LRRC7	1.45e-05	171	129	8	int:ACTN2
Interaction	DCLK1 interactions	MAGI1 KIF13B MELK SHANK3 SYDE1 SPICE1 SH3BP4	1.77e-05	127	129	7	int:DCLK1
Interaction	MAST3 interactions	MAGI1 KIF13B MELK SYDE1 TULP3 MAST4 EIF2S1	1.96e-05	129	129	7	int:MAST3
Interaction	ANKRD34A interactions	MAGI1 KIF13B MELK SYDE1 SH3BP4	2.23e-05	53	129	5	int:ANKRD34A
Interaction	TESK2 interactions	MAGI1 KIF13B CAD MELK SYDE1 SH3BP4	3.76e-05	97	129	6	int:TESK2
GeneFamily	Myosin heavy chains	MYH2 MYH3 MYH6 MYH8	7.18e-07	15	89	4	1098
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF13B KIF4A KIFC2 KIF4B KIFC1	3.02e-06	46	89	5	622
GeneFamily	ADAMTS like	ADAMTSL1 ADAMTSL3	4.95e-04	7	89	2	947
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH6 SMC4 KIF4A MELK C4orf54 NEIL3 PLXNA1 KIFC1	8.51e-08	184	133	8	d1e0e3b0eed2db8a5b7e3d6f81294667e4ba64e5
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	MCM8 KIF4A MELK PTPRB DACH2 NEIL3 LRRC7 KIFC1	1.09e-07	190	133	8	e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SMC4 KIF4A MELK SPIN4 SHANK3 PTPRB NEIL3 KIFC1	1.38e-07	196	133	8	eb8c9a4a5eb21d43ff7b25deae5896c236f669b9
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SMC4 KIF4A PKD2L1 MELK NEIL3 CCL18 LYZ KIFC1	1.55e-07	199	133	8	13ff6c26ebcc663ef8e5559ab9be99dab848abe7
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SMC4 KIF4A PKD2L1 MELK NEIL3 CCL18 LYZ KIFC1	1.61e-07	200	133	8	5e1b38e2aa8901bfb2623249f7b6302e97d56ace
ToppCell	LPS-antiTNF-Endothelial-Endothelial-FOXM1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SMC4 KIF4A MELK DDX11 PTPRB NEIL3 KIFC1	6.11e-07	163	133	7	5285318c52aa31c9b22dc2ffff078e32e408604d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SMC4 KIF4A MELK SPIN4 NEIL3 KIF4B KIFC1	6.63e-07	165	133	7	eec2d327c94832d1390314c93ef6a2be4648478b
ToppCell	facs-Aorta\|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH8 RNF186 DEPP1 LIMS2 PTPRB KANK3 DNAH11	1.02e-06	176	133	7	0b3491451be02c18a16cdb875645be47eb867a7f
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-cycling_ENCC/glia\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SMC4 KIF4A CHADL MELK NEIL3 MPPED2 KIFC1	1.43e-06	185	133	7	282b3de8850f3c21704339e8d8737b432a43441a
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIF4A PKD2L1 MELK NEIL3 CCL18 LYZ KIFC1	1.76e-06	191	133	7	d6e158f16a183c9203c057192342e9b83e79bc89
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIF4A PKD2L1 MELK NEIL3 CCL18 LYZ KIFC1	1.76e-06	191	133	7	7cb5c6f2cf27f3503d1b313e402a7410dfe6473e
ToppCell	(3)_Macrophage_Dividing\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	KIF4A PKD2L1 MELK NEIL3 KIF4B CCL18 KIFC1	1.76e-06	191	133	7	b42f0b89bb94fd43786ff50f1caeb3ebfbbb43fd
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	MCM8 SMC4 KIF4A FANCM MELK DDX11 KIFC1	1.89e-06	193	133	7	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIF4A MELK NEIL3 CCL18 LYZ KYNU KIFC1	1.89e-06	193	133	7	444de545117dae8ab24a22880583ac2f0b2d6eac
ToppCell	3'_v3-Lung-Myeloid_Mac-Cycling_Myeloid-Mac\|Lung / Manually curated celltypes from each tissue	RNF186 MCM8 SMC4 KIF4A MELK NEURL3 KIFC1	1.96e-06	194	133	7	a8ae49157ca3f9e8b3f1750a995aee012dc859b6
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-Cycling_plasma_cell\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SMC4 KIF4A MELK HMCES NEIL3 SEMA4A KIFC1	1.96e-06	194	133	7	06b8dc2e46f833707d5b68b324b4ff6c4d0dccf9
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	SMC4 KIF4A MELK DDX11 NEIL3 KIF4B KIFC1	2.09e-06	196	133	7	9591a6a3477ed6a1e2e016f7542e38603d8b16cb
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SMC4 KIF4A MELK NEIL3 LYZ KYNU KIFC1	2.09e-06	196	133	7	35cc0986dc3fc4b89e960a565b8f9810b1688e09
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SMC4 KIF4A MELK NEIL3 CCL18 LYZ KIFC1	2.17e-06	197	133	7	954d4deaeba50c5b3faf52105c4cde961a682be1
ToppCell	PCW_10-12-Endothelial-Endothelial_cycling-endo_proliferating2_(14)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DEPP1 KIF4A SHANK3 LIMS2 PTPRB KANK3 KIFC1	2.17e-06	197	133	7	491e12a5fca06b86443c0173f5fa750ea3b8a715
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SMC4 KIF4A MELK SPIN4 SHANK3 PTPRB KIFC1	2.17e-06	197	133	7	76b61e60a757e58b465569538e632d6d9953e89a
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SMC4 KIF4A MELK NEIL3 CCL18 LYZ KIFC1	2.17e-06	197	133	7	2a89a724e8c15a5bb167fdad7eed31444d8c3d68
ToppCell	distal-Hematologic-Proliferating_NK/T-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	APOBEC3H SMC4 KIF4A MELK NEIL3 KIF4B KIFC1	2.17e-06	197	133	7	04b10879e48c101d1de449db0bc6b6484090b965
ToppCell	severe_COVID-19-T/NK_proliferative\|severe_COVID-19 / disease group, cell group and cell class (v2)	MCM8 APOBEC3H SMC4 KIF4A MELK DDX11 KIFC1	2.24e-06	198	133	7	ed86b0247006befe55400c287d334d2202b470bd
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SMC4 KIF4A PKD2L1 MELK NEIL3 LYZ KIFC1	2.24e-06	198	133	7	428182c71f009906c581e02257e545ea5fb99650
ToppCell	Biopsy_Other_PF-Epithelial-Proliferating_Epithelial_cells\|Biopsy_Other_PF / Sample group, Lineage and Cell type	CDSN MCM8 SMC4 KIF4A MELK NEIL3 KIFC1	2.32e-06	199	133	7	d73667e2e93026d95184e24ff0bc90afd1fb74a9
ToppCell	Biopsy_IPF-Immune-Proliferating_Macrophages\|Biopsy_IPF / Sample group, Lineage and Cell type	SMC4 KIF4A MELK NEIL3 CCL18 LYZ KIFC1	2.39e-06	200	133	7	8abb2c25422717e994468ac02d8260344341467f
ToppCell	Thalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a7-Tac2-Excitatory_Neuron.Slc17a7.Tac2.Syt15_(Medial_habenula)\|Thalamus / BrainAtlas - Mouse McCarroll V32	MYH2 MYH6 RXFP2 IQCM TAT	3.49e-06	77	133	5	7f624e9262bd0dc2ac4176f43c91a4bc0f521fe5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	APOBEC3H SHANK3 LIMS2 PTPRB GSDMA KIFC1	5.15e-06	146	133	6	281144e293e8c93a425c2606d2188cb2838e667f
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	KIF4A ADAMTSL3 MELK DDX11 NEIL3 KIFC1	9.01e-06	161	133	6	0dd1401b4c990d49fccb702a9f9867590a58e203
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	KIF4A ADAMTSL3 MELK DDX11 NEIL3 KIFC1	9.01e-06	161	133	6	b6a31c033edc74f23a20aab1f18e80cc83ffee4c
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	KIF4A ADAMTSL3 MELK DDX11 NEIL3 KIFC1	9.01e-06	161	133	6	efb811dda4d73107983a5f68302bdcf4f408d5b4
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	KIF4A ADAMTSL3 MELK DDX11 NEIL3 KIFC1	9.01e-06	161	133	6	28d5dbd20c9f8e0069f172d552997a044790e1a7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SHANK3 LIMS2 PTPRB KANK3 GSDMA RPL13A	9.67e-06	163	133	6	73c03e29a6d7a6863c5e9aa5e8b963ef691f1ddb
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SMC4 KIF4A MELK NEIL3 KIF4B KIFC1	1.07e-05	166	133	6	2642544070564debe2deb2938d2c33997bf5ef02
ToppCell	Dividing_Macrophages-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	APOBEC3H PKD2L1 MELK NEIL3 MUC5AC KIFC1	1.07e-05	166	133	6	ea95b94ccc2ac67df741b30c27f4ae698925875f
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SMC4 KIF4A MELK NEIL3 KIF4B KIFC1	1.11e-05	167	133	6	50c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SMC4 KIF4A MELK KANK3 NEIL3 KIFC1	1.11e-05	167	133	6	bc132b51dec4e8f1cd2b2cd89f83641976e09292
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_1\|390C / Donor, Lineage, Cell class and subclass (all cells)	KIF4A MELK NEIL3 LYZ KYNU KIFC1	1.15e-05	168	133	6	2082b15fc7935a211f1c61506b305af5501a21ad
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SMC4 KIF4A MELK NEIL3 KIF4B KIFC1	1.15e-05	168	133	6	d35944fd9fea9934ce1e76b2b35d48e2300cca61
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SMC4 KIF4A MELK NEIL3 GPC5 KIFC1	1.19e-05	169	133	6	e7514956b2e4298222ec443f98b2f5289451786e
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SMC4 KIF4A MELK DDX11 NEIL3 KIFC1	1.19e-05	169	133	6	e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GAPT KIF4A MELK NEIL3 LYZ KIFC1	1.27e-05	171	133	6	55c7bf7211587fa08df13c0a4ff5b78a85d5439e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DEPP1 SHANK3 LIMS2 PTPRB KANK3 RPL13A	1.36e-05	173	133	6	3877cead288ce9509e6cccf57e55ec5e1bd7ce18
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SMC4 KIF4A MELK NEIL3 LYZ KIFC1	1.40e-05	174	133	6	7b318796728001c17b4043d2b033330c7be40c78
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4/8-lo-Cycling_T\|Lung / Manually curated celltypes from each tissue	MAGI1 SMC4 KIF4A MELK NEIL3 KIFC1	1.50e-05	176	133	6	a40dfd8c4ba16757ff929b2f03a0628acf334de4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MCM8 SMC4 KIF4A MELK NEIL3 KIFC1	1.65e-05	179	133	6	88d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCell	LPS-IL1RA-Endothelial-Endothelial-FOXM1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SMC4 KIF4A MELK DDX11 NEIL3 KIFC1	1.70e-05	180	133	6	334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCell	Control-Myeloid-Alveolar_macrophages\|Control / group, cell type (main and fine annotations)	TBXAS1 CD83 RXFP2 CCL18 LYZ KYNU	1.75e-05	181	133	6	8d2102c8c86c59a82610f26f90946b290552e666
ToppCell	10x5'-Liver-Lymphocytic_T_CD4/8-lo-Cycling_T\|Liver / Manually curated celltypes from each tissue	SMC4 KIF4A MELK NEIL3 KIF4B KIFC1	1.81e-05	182	133	6	81557cdc88777f3bd4e1dd18a760b08fc29122ef
ToppCell	facs-Aorta-Heart-3m-Myeloid-macrophage\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA4D KIF4A CD83 MELK NEIL3 SEMA4A	1.81e-05	182	133	6	df26388c0c46d1c4775103c8e802937b4d4e7470
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-cycling_ENCC/glia\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SMC4 KIF4A MELK GLUD2 MPPED2 KIFC1	1.86e-05	183	133	6	29b62dd542bc3f8df843998f577724f3818d4271
ToppCell	COVID-19-Endothelial_cells-Arterial_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	MAGI1 DEPP1 SHANK3 LIMS2 PTPRB MAST4	1.92e-05	184	133	6	0f19494789f38ab1a420545e15e748ca7eb345c3
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|lymph-node_spleen / Manually curated celltypes from each tissue	KIF4A SIRT6 MELK TIMM21 KANK3 LYZ	2.11e-05	187	133	6	3c10b8501226c69d71bcd99dc1c064a3c2154f87
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_8\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GAPT CD83 SH3BP4 NEU1 SEMA4A KYNU	2.17e-05	188	133	6	8431991e68b8e9c5eb72212460f6da679ea3b85a
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_8\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GAPT CD83 SH3BP4 NEU1 SEMA4A KYNU	2.17e-05	188	133	6	d8f10b3ad11bc99a63f44560e39791085256e5c8
ToppCell	COVID-19-lung-Artery_EC\|lung / Disease (COVID-19 only), tissue and cell type	MAGI1 DEPP1 SHANK3 LIMS2 PTPRB MAST4	2.17e-05	188	133	6	eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 DEPP1 SHANK3 LIMS2 PTPRB KANK3	2.17e-05	188	133	6	117dc80fa940e6aa1b0187a43fdde33f3fcb578f
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	KIF13B CILP GAPT SHANK3 CILP2 KANK3	2.17e-05	188	133	6	c90669b51e1902fe7726555290c91c92a911df83
ToppCell	PCW_10-12-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	RNF186 ADAMTSL1 GPC5 PAX9 MUC5AC ATP4A	2.17e-05	188	133	6	3cfba3addcc9058f4ec31ad96261f79988f551a0
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PKD2L1 CD83 HSD3B7 CCL18 LYZ KYNU	2.24e-05	189	133	6	1f4fe19e500bfedd48b1f34827a44e796f6db3e1
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PKD2L1 CD83 HSD3B7 CCL18 LYZ KYNU	2.24e-05	189	133	6	bfa1dfc93ad33a9dbef316c0591b950d062b35eb
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SMC4 KIF4A MELK PTPRB NEIL3 KIFC1	2.30e-05	190	133	6	31de1727822e9818652946dfb962daee77ffad68
ToppCell	facs-SCAT-Fat-18m-Endothelial-nan\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 DEPP1 SHANK3 LIMS2 PTPRB KANK3	2.30e-05	190	133	6	b0c9dae8189d407c94964c6bfe3ef92035245357
ToppCell	facs-MAT-Fat-18m-Endothelial\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 DEPP1 SHANK3 LIMS2 PTPRB KANK3	2.30e-05	190	133	6	34e56c5e7ea6a8f227dbaefe73cbb8818d18b523
ToppCell	facs-MAT-Fat-18m-Endothelial-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 DEPP1 SHANK3 LIMS2 PTPRB KANK3	2.30e-05	190	133	6	14cdb660ad3aabcf49572173e7628d8b99dcbe6f
ToppCell	facs-SCAT-Fat-18m-Endothelial\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 DEPP1 SHANK3 LIMS2 PTPRB KANK3	2.30e-05	190	133	6	ee63dc04e91ad49aa7820c98e97261176ecebaa6
ToppCell	normal_Pleural_Fluid-T/NK_cells-Undetermined\|normal_Pleural_Fluid / Location, Cell class and cell subclass	SMC4 KIF4A MELK NEIL3 KIF4B KIFC1	2.30e-05	190	133	6	165c61443ff0c8efbdad3b052bb00f46d81c5203
ToppCell	facs-SCAT-Fat-18m-Endothelial-endothelial_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 DEPP1 SHANK3 LIMS2 PTPRB KANK3	2.30e-05	190	133	6	0e50808bfc3d0820524c8470ae3e8250819d65b2
ToppCell	facs-MAT-Fat-18m-Endothelial-endothelial_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 DEPP1 SHANK3 LIMS2 PTPRB KANK3	2.30e-05	190	133	6	9aaa48f3aad813c87a45efdbb67d255c94f6e6a4
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	MCM8 SMC4 KIF4A MELK DDX11 KIFC1	2.30e-05	190	133	6	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	Endothelial-D_(cycle)\|World / shred on cell class and cell subclass (v4)	SMC4 KIF4A MELK PTPRB NEIL3 KIFC1	2.37e-05	191	133	6	49a4d8f181558e3be9527a8ff9a178f3bb01323c
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|356C / Donor, Lineage, Cell class and subclass (all cells)	KIF4A PKD2L1 MELK NEIL3 CCL18 KIFC1	2.37e-05	191	133	6	a2c235a55094e4fd5273d764c9e2967116b48c23
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SMC4 KIF4A PKD2L1 MELK LYZ KIFC1	2.37e-05	191	133	6	b85a0978dc1e8af4f49423f56dcfd52efce09ed1
ToppCell	droplet-Heart\|droplet / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH6 DEPP1 LIMS2 TXNIP PTPRB KANK3	2.44e-05	192	133	6	67a7e07a11091120edbccf739836235c422ec9c6
ToppCell	COVID-19-kidney-AQP1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADAMTSL1 SHANK3 LIMS2 PTPRB KANK3 MPPED2	2.44e-05	192	133	6	27ff3621e177e7932dd44dd6baa81551ea75a874
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Endothelial-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 DEPP1 SHANK3 LIMS2 PTPRB KANK3	2.44e-05	192	133	6	8f20d3511dcb44445592b17d005a53da0052ae56
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Endothelial-endothelial_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 DEPP1 SHANK3 LIMS2 PTPRB KANK3	2.44e-05	192	133	6	0986b7900021efe2a4df84a935e7c9a0af1b0e57
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Endothelial\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 DEPP1 SHANK3 LIMS2 PTPRB KANK3	2.44e-05	192	133	6	b28d294e42b303d1db6060231d84d7b9e4d9fccf
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAGI1 SRPK2 SHANK3 PTPRB MAST4 DACH2	2.52e-05	193	133	6	6e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCell	IPF-Endothelial-VE_Arterial\|IPF / Disease state, Lineage and Cell class	MAGI1 DEPP1 SHANK3 LIMS2 PTPRB MAST4	2.52e-05	193	133	6	bf83b1fe9d38408f30eee4eb634341c04ef82791
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-cycling_ENCC/glia\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SMC4 KIF4A MELK NEIL3 MPPED2 KIFC1	2.52e-05	193	133	6	e7b2d99342e3eb4a05d298c2f124dd20bed8a743
ToppCell	IPF-Endothelial-VE_Arterial\|World / Disease state, Lineage and Cell class	MAGI1 DEPP1 SHANK3 LIMS2 PTPRB MAST4	2.52e-05	193	133	6	70a9aadda83a97e06e9bc2d1327ce60dd3c58767
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	MCM8 KIF4A MELK DACH2 NEIL3 KIFC1	2.52e-05	193	133	6	516ea2c12bdc7a5dc676159d627e36f6abe13ef0
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 SHANK3 LIMS2 PTPRB KANK3 GPC5	2.52e-05	193	133	6	1f978e102a029a6beb10913052cd0a20c7253e8e
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SMC4 KIF4A MELK NEIL3 LYZ KIFC1	2.59e-05	194	133	6	e5b81a8e52259a54a911c1c2ac932c98c988318d
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	MCM8 SMC4 KIF4A MELK NEIL3 KIFC1	2.59e-05	194	133	6	f9070035553bc68106a9e0bdf4b507715a138aba
ToppCell	(1)_T_cells_Dividing\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	APOBEC3H SMC4 KIF4A MELK DDX11 KIFC1	2.59e-05	194	133	6	8f313071933451780309d2174ed27d8cdc734343
ToppCell	COVID-19-Myeloid-TRAM2\|COVID-19 / Condition, Lineage and Cell class	CD83 LIMS2 ACOT2 CCL18 LYZ KYNU	2.59e-05	194	133	6	c5bdf2b58c10dcb09797ddaf46b2e6c80d10399f
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAGI1 SRPK2 SHANK3 PTPRB MAST4 DACH2	2.59e-05	194	133	6	0b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell	LPS_only-Endothelial\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAGI1 DEPP1 SHANK3 PTPRB MAST4 DACH2	2.59e-05	194	133	6	58f069efdefa0366033764446b9d6ffd4a17807e
ToppCell	LPS_only-Endothelial-Endothelial\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAGI1 DEPP1 SHANK3 PTPRB MAST4 DACH2	2.59e-05	194	133	6	bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SMC4 KIF4A MELK PTPRB NEIL3 KIFC1	2.59e-05	194	133	6	3a49c7c86036e09a8cd0114988380d04ad1a26fb
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating\|367C / Donor, Lineage, Cell class and subclass (all cells)	SMC4 KIF4A MELK NEIL3 KIF4B KIFC1	2.59e-05	194	133	6	a12b64945e10f00aa983678a02586c59badc1570
ToppCell	Control-Endothelial\|Control / Disease state, Lineage and Cell class	MAGI1 DEPP1 SHANK3 PTPRB KANK3 ACKR2	2.59e-05	194	133	6	485fe5538fabec457b9a51feb641f2a91cbf4e18
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SMC4 KIF4A MELK NEIL3 LYZ KIFC1	2.67e-05	195	133	6	db1660ce74819cd816bdcfcae5efb3aad82cce66
ToppCell	COVID-19-T_cells-Cycling_NK/T_cells\|COVID-19 / group, cell type (main and fine annotations)	MCM8 SMC4 KIF4A MELK NEIL3 KIFC1	2.67e-05	195	133	6	764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell	(1)_T_cells-(1)_T_cells_Dividing\|(1)_T_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	MCM8 SMC4 KIF4A MELK DDX11 KIFC1	2.67e-05	195	133	6	cf00a0b4f341f0487d5b37810abe2952fdd3f6f2
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SMC4 KIF4A MELK PTPRB NEIL3 KIFC1	2.67e-05	195	133	6	5790b47b0e028e49b99bda8d6d9e80ac79208cdf
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SMC4 KIF4A MELK PTPRB NEIL3 KIFC1	2.74e-05	196	133	6	20383d576708b7e4bfce3e9fe40548cce496e3cb
Drug	l-413	CAD GLUD1 GLUD2	1.76e-06	5	129	3	CID000012475
Drug	Leucomisine [17946-87-1]; Up 200; 16.2uM; PC3; HT_HG-U133A	KIF13B SMC4 LIMS2 PHF1 MAST4 HPN DSTYK KYNU TAT	2.06e-06	199	129	9	7125_UP
Drug	isodiazinon	GLUD1 GLUD2 FECH	3.51e-06	6	129	3	CID000133913
Drug	SM-2	MYH2 MYH3 MYH6 MYH8 GLUD1 GLUD2	1.02e-05	87	129	6	CID000486033
Drug	indole-3-pyruvic acid	GLUD1 GLUD2 KYNU TAT	1.13e-05	25	129	4	CID000000803
Drug	Ald1.1-H_000455; Up 200; 10uM; PC3; HT_HG-U133A	EPHB3 DEPP1 SRPK2 ARTN SYDE1 LIMS2 MAST4 SEMA4A	1.36e-05	191	129	8	7547_UP
Drug	ADP-ribosylcysteine	SIRT6 GLUD1 GLUD2	2.84e-05	11	129	3	CID003035804
Drug	phenyltriethoxysilane	GLUD1 GLUD2	3.19e-05	2	129	2	CID000013075
Drug	G-3SH	GLUD1 GLUD2	3.19e-05	2	129	2	CID000174237
Drug	iodoacetyldiethylstilbestrol	GLUD1 GLUD2	3.19e-05	2	129	2	CID006455327
Drug	methylmercuric bromide	GLUD1 GLUD2	3.19e-05	2	129	2	CID000068175
Drug	5-methylisophthalate	GLUD1 GLUD2	3.19e-05	2	129	2	CID000068137
Drug	x 1 s	GLUD1 GLUD2	3.19e-05	2	129	2	CID000409694
Drug	N-ethylmaleimide	KIF13B MYH2 MYH3 MYH6 MYH8 KIF4A SIRT6 KIFC2 PDHX GTF3C1 EIF2S1 KIFC1	3.49e-05	511	129	12	CID000004362
Drug	N-carbamylglutamate	SSTR5 GLUD1 GLUD2	4.88e-05	13	129	3	CID000121396
Drug	Cocaine	EPHB3 SEMA4D MYH6 TNFRSF14 SHANK3 LIMS2 PPP2R2C PTPRB EIF2S1 PRKCG LRRC7 NKX2-2 ACKR2 GPC5 EIF3C SEMA4A HERC1 PCDH8 GABBR1 KIFC1	4.98e-05	1314	129	20	ctd:D003042
Drug	B0683	MYH2 MYH3 MYH6 MYH8 GLUD1 GLUD2	5.51e-05	117	129	6	CID006398969
Drug	troglitazone	PRLHR PARP8 DEPP1 SMC4 KIF4A CD83 MELK COG8 TXNIP PPP2R2C EIF2S1 RXFP2 NEIL3 ACOT2 EIF3C SEMA4A RPL13A LYZ HSPA2 TAT	5.83e-05	1329	129	20	ctd:C057693
Disease	autosomal dominant hyaline body myopathy (implicated_via_orthology)	MYH2 MYH3 MYH6 MYH8	8.11e-08	10	133	4	DOID:0111269 (implicated_via_orthology)
Disease	distal arthrogryposis type 2B3 (implicated_via_orthology)	MYH2 MYH3 MYH6 MYH8	8.11e-08	10	133	4	DOID:0111602 (implicated_via_orthology)
Disease	distal arthrogryposis type 1 (implicated_via_orthology)	MYH2 MYH3 MYH6 MYH8	8.11e-08	10	133	4	DOID:0111596 (implicated_via_orthology)
Disease	dilated cardiomyopathy 1S (implicated_via_orthology)	MYH2 MYH3 MYH6 MYH8	8.11e-08	10	133	4	DOID:0110454 (implicated_via_orthology)
Disease	congenital myopathy 6 (implicated_via_orthology)	MYH2 MYH3 MYH6 MYH8	8.11e-08	10	133	4	DOID:0080719 (implicated_via_orthology)
Disease	inclusion body myositis (implicated_via_orthology)	MYH2 MYH3 MYH6 MYH8	8.11e-08	10	133	4	DOID:3429 (implicated_via_orthology)
Disease	distal arthrogryposis type 2A (implicated_via_orthology)	MYH2 MYH3 MYH6 MYH8	8.11e-08	10	133	4	DOID:0111605 (implicated_via_orthology)
Disease	familial hypertrophic cardiomyopathy (implicated_via_orthology)	MYH2 MYH3 MYH6 MYH8	8.11e-08	10	133	4	DOID:0080326 (implicated_via_orthology)
Disease	distal myopathy (implicated_via_orthology)	MYH2 MYH3 MYH6 MYH8	1.90e-07	12	133	4	DOID:11720 (implicated_via_orthology)
Disease	myotonia congenita (implicated_via_orthology)	MYH2 MYH3 MYH6 MYH8	1.90e-07	12	133	4	DOID:2106 (implicated_via_orthology)
Disease	restrictive cardiomyopathy (implicated_via_orthology)	MYH2 MYH3 MYH6 MYH8	2.73e-07	13	133	4	DOID:397 (implicated_via_orthology)
Disease	distal arthrogryposis (implicated_via_orthology)	MYH2 MYH3 MYH6 MYH8	5.18e-07	15	133	4	DOID:0050646 (implicated_via_orthology)
Disease	fascioliasis (biomarker_via_orthology)	GLUD1 GLUD2	6.03e-05	3	133	2	DOID:885 (biomarker_via_orthology)
Disease	myopathy (implicated_via_orthology)	MYH2 MYH3 MYH6 MYH8	6.58e-05	48	133	4	DOID:423 (implicated_via_orthology)
Disease	CONOTRUNCAL HEART MALFORMATIONS	NKX2-6 NKX2-5	1.20e-04	4	133	2	217095
Disease	Conotruncal heart malformations	NKX2-6 NKX2-5	1.20e-04	4	133	2	cv:C1857586
Disease	tetradecadienedioate (C14:2-DC) measurement	PKD2L1 ACOT2	2.99e-04	6	133	2	EFO_0800585
Disease	childhood absence epilepsy (biomarker_via_orthology)	GLUD1 GLUD2	2.99e-04	6	133	2	DOID:1825 (biomarker_via_orthology)
Disease	CONOTRUNCAL HEART MALFORMATIONS (disorder)	NKX2-6 NKX2-5	2.99e-04	6	133	2	C1857586
Disease	cardiomyopathy (implicated_via_orthology)	MYH2 MYH3 MYH6 MYH8	3.03e-04	71	133	4	DOID:0050700 (implicated_via_orthology)
Disease	atrial heart septal defect (is_implicated_in)	MYH6 NKX2-5	4.17e-04	7	133	2	DOID:1882 (is_implicated_in)
Disease	dilated cardiomyopathy (implicated_via_orthology)	MYH2 MYH3 MYH6 MYH8	4.79e-04	80	133	4	DOID:12930 (implicated_via_orthology)
Disease	Fanconi anemia (implicated_via_orthology)	FANCM FAN1	5.55e-04	8	133	2	DOID:13636 (implicated_via_orthology)
Disease	sarcoma (is_implicated_in)	PDHX PTPRB	5.55e-04	8	133	2	DOID:1115 (is_implicated_in)
Disease	Distal arthrogryposis	MYH3 MYH8	7.11e-04	9	133	2	cv:C0265213
Disease	Ostium secundum atrial septal defect	MYH6 NKX2-5	7.11e-04	9	133	2	C0344724
Disease	decadienedioic acid (C10:2-DC) measurement	PKD2L1 ACOT2	8.86e-04	10	133	2	EFO_0800598
Disease	ventricular septal defect (is_implicated_in)	NKX2-6 NKX2-5	1.77e-03	14	133	2	DOID:1657 (is_implicated_in)
Disease	lifestyle measurement, alcohol consumption measurement	PPP2R2C GSDMA ACKR2 DHX34	1.85e-03	115	133	4	EFO_0007878, EFO_0010724
Disease	hepatic encephalopathy (biomarker_via_orthology)	GLUD1 GLUD2	2.04e-03	15	133	2	DOID:13413 (biomarker_via_orthology)
Disease	pyroglutamine measurement	NTMT1 CARNS1 DNPEP	2.30e-03	58	133	3	EFO_0005408
Disease	Tetralogy of Fallot	NKX2-6 NKX2-5	2.32e-03	16	133	2	C0039685
Disease	Lipoidosis	DEPP1 HPN	3.28e-03	19	133	2	C0023794
Disease	Hereditary Non-Polyposis Colon Cancer Type 2	FAN1 SEMA4A	3.28e-03	19	133	2	C1333991
Disease	Colorectal cancer, hereditary nonpolyposis, type 1	FAN1 SEMA4A	3.28e-03	19	133	2	C2936783
Disease	macrophage inflammatory protein 1b measurement	FBXO10 POMGNT2 ACKR2 CCL18	3.40e-03	136	133	4	EFO_0008219
Disease	ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder)	NKX2-6 NKX2-5	4.39e-03	22	133	2	C1843687

Protein segments in the cluster

Peptide	Gene	Start	Entry
SRIGCVLVRLRPAGQ	ACKR2	231	O00590
GLRLRICHGKPVTQV	BOP1	526	Q14137
AVLKPRRVCVGGKRR	PPP2R2C	386	Q9Y2T4
KGGRCACPRVIRKVL	ARHGEF25	6	Q86VW2
LAGRVIVKCPTSGRL	DNPEP	146	Q9ULA0
QACRKGRPAVSLRDI	DEPP1	71	Q9NTK1
RKVRGGLPLVTCALR	HSD3B7	176	Q9H2F3
TIPKGCVLAFRVRQL	GSDMA	196	Q96QA5
IRRGGIPVLRSNLIC	FBXO10	606	Q9UK96
RLERIKIPGVRAQGR	APOBEC3H	176	Q6NTF7
VCERGGLPRVRSVKV	CRYBA2	36	P53672
VCRTQGDRPLLSKVV	CARNS1	236	A5YM72
RLQLKIILCFSPVGR	DNAH11	2976	Q96DT5
CKRLQAHGRRKPQII	ACOT2	401	P49753
KPGVILLTKRGRQIC	CCL18	56	P55774
CRLQGPRRVDKRTLV	C1QTNF12	156	Q5T7M4
TKPCGLQRGDRLAVI	ACSM4	106	P0C7M7
CRSIRDILAQVKPLG	CDSN	496	Q15517
KAPIRVRNLTIRAGA	DMRTC1;	6	Q5HYR2
AIQPGVNRCKLITRK	DACH2	136	Q96NX9
PRKVTNCLHIKRVVG	RCBTB1	171	Q8NDN9
RRVAVPVLVRDGKPC	NKX2-6	206	A6NCS4
QARKRECVRVPRGGI	CPSF7	171	Q8N684
RRERCRPIDLITKGQ	IQCM	116	A0A1B0GVH7
CQLQKPDVVGIRRQR	MELK	616	Q14680
RNLSGKVILRVTGCP	CD83	116	Q01151
GCVELLNTVQRRVRP	MPPED2	231	Q15777
CQGRTVPLAVLQLRV	PTPRB	461	P23467
KCIPVRDRGFLVQTI	PARP8	481	Q8N3A8
RLRIVELAQLGIRPC	PAX9	26	P55771
CRRPIEGRVVNALGK	LIMS2	201	Q7Z4I7
VACAKRVVRDPQGIR	LYZ	111	P61626
QRVKQIVDSPRCRGL	MAGI1	666	Q96QZ7
RDGLVKLSQRILGPC	TAT	306	P17735
GCTLNGEKIRARVLP	NEIL3	6	Q8TAT5
LRGTVVRVSNIKPLC	MCM8	221	Q9UJA3
KIIGRLVPCRCFRGE	LRRC7	6	Q96NW7
KLLEQVNRICGRPVR	GPC5	336	P78333
VKVFRSRIACLPGGR	KIAA1755	571	Q5JYT7
VCRGEREVVGPKVRK	GABBR1	66	Q9UBS5
KLIRIGRNECVVVIR	EIF2S1	61	P05198
RGCRLRSQLVPVRAL	ARTN	121	Q5T4W7
VCNGNARRGIKVPKR	FANCM	1486	Q8IYD8
TRGRKCKPIFVQIAR	HERC1	4481	Q15751
ELKGNIRVFCRVRPV	KIFC1	306	Q9BW19
PKTAVVLRCPARRVR	ADAMTSL1	891	Q8N6G6
IGPNKRAVRRLRTAC	HSPA2	256	P54652
VLEGIRICRKGFPSR	MYH8	701	P13535
VRLGVRVGKVLCSPV	PLXNA1	896	Q9UIW2
QACILAVGRFRPVLK	PDHX	436	O00330
PGPRAATCKVIVRIR	PCDH8	331	O95206
EGIRICRKGFPSRIL	MYH2	706	Q9UKX2
NPCLILVVRRENIVG	HERC4	706	Q5GLZ8
VCTKTFLGPRIIGLR	GAPT	56	Q8N292
LRTNIQLPACLRVIG	COG8	216	Q96MW5
EVCRGRLKQPGRREV	EPHB3	646	P54753
RPLFCRKGALRQKVV	PRKCG	16	P05129
NNIIRSGEKICRRPE	MUC5AC	1771	P98088
NNIIRSGEKICRRPE	MUC5AC	3981	P98088
RVICSRKGRVSVPLR	PDPK2P	376	Q6A1A2
SLIQTIRRVVKGRPG	POMGNT2	456	Q8NAT1
VVCGDPVTKVKPRRR	DDX11	931	Q96FC9
LVVFVGKLRCRPVAV	GPR42	36	O15529
RRIAVPVLVRDGKPC	NKX2-5	216	P52952
PVGTREIKCCIRQIQ	DSTYK	451	Q6XUX3
QDCGRRKLPVDRIVG	HPN	151	P05981
QRRQRVCSGEGLPKA	PCDHA10	751	Q9Y5I2
LITRLLEVRGCRPGK	PPP1CB	11	P62140
QPLRVRGCILTLVER	EIF3C	436	Q99613
VRRQLKVILCFSPVG	DNAH17	2921	Q9UFH2
RVRGILRIIKPCNHV	GLUD1	101	P00367
EQGCLKRPVSRKVGR	MAST4	1506	O15021
KGIPVRVALRCRPLV	KIF4A	6	O95239
KGIPVRVALRCRPLV	KIF4B	6	Q2VIQ3
CVALQRQLSRPRGVA	KANK3	556	Q6NY19
GLCERGRKNILLVPI	FECH	321	P22830
RRTPIKGRQCGADKV	CHADL	741	Q6NUI6
VPARLQTRCGAIRAK	C4orf54	586	D6RIA3
QPRRIACISLAKRVG	DHX34	211	Q14147
PDAVLKCRTAGIRVI	ATP4A	611	P20648
RVRGILRIIKPCNHV	GLUD2	101	P49448
RSFKVPLGKGRRCVV	HMCES	106	Q96FZ2
GRLPELKGNIRVLCR	KIFC2	401	Q96AC6
LKGNIRVLCRLRPGT	KIFC2	406	Q96AC6
LCLTQVLRRVTGNPR	PAOX	401	Q6QHF9
VCRGGPEKVRRLQLR	PHF1	236	O43189
SKVVLGRVGLNCPRL	FBXL21P	326	Q9UKT6
RRCKGSLRPNGIIVI	NTMT1	151	Q9BV86
RKVTAVPGGLICSLR	RNF186	86	Q9NXI6
RICKGPRAVFSRILL	FAN1	536	Q9Y2M0
ILSVGIGCVKVRPLR	KIF13B	1051	Q9NQT8
QEILRRPIVACELGR	RTF2	41	Q9BY42
IIQKCVGQIERRGLR	SYDE1	416	Q6ZW31
VRVSVKLRNRVVPGC	PRLHR	246	P49683
TKNVLVVGRARPSLC	SH3BP4	716	Q9P0V3
CAVLRDNTGVRLKRP	GIN1	401	Q9NXP7
KQREPRKGRLIVCGH	NEU1	206	Q99519
PLRALRARGKVQGCE	SEMA4A	706	Q9H3S1
IRPGKRQTSVILICI	RXFP2	531	Q8WXD0
EGIRICRKGFPNRIL	MYH3	701	P11055
RRVAVPVLVRDGKPC	NKX2-2	201	O95096
FRVLIPRIARVCKGD	SEMA4D	246	Q92854
LEGIRICRKGFPNRI	MYH6	701	P13533
RRGGRLVIVNLQPTK	SIRT6	231	Q8N6T7
VKVRAAGVRVGCVRR	SSTR5	226	P35346
VNRCGPRVGVRKTPK	SPICE1	6	Q8N0Z3
DRTLVKVIPQGSCRR	CILP	1021	O75339
QKCLPPRGLVRGRVV	CILP2	466	Q8IUL8
PERTRGRCAVGKVRV	LINC02881	86	B7Z368
DLQVPGDVKRVCRRL	C10orf143	16	A0A1B0GUT2
GRRNGPVKLRLTVLC	SMURF2	6	Q9HAU4
IRAIVGNVLRAPCRR	URGCP	431	Q8TCY9
PRSCLGVRLGLLEVK	TBXAS1	476	P24557
RASGLQPCVIVIRVL	ZFR2	781	Q9UPR6
QVLLGRKVVVVRCEG	RPL13A	26	P40429
VRVGIPDLQQTKCLR	SHANK3	11	Q9BYB0
KPTFLTRRNIVGCRI	SPIN4	31	Q56A73
PVRCVKSIIRQVLQG	SRPK2	186	P78362
ICQTFVGRALQPVRK	ERVK-8	171	P63133
PALSRKQRTVLVVCG	YJEFN3	111	A6XGL0
GRLNEPIKVLCRRVE	SMC4	261	Q9NTJ3
GVPRLRQLKVRNDSC	PKD2L1	196	Q9P0L9
AVRKLRQELGICPAV	CAD	886	P27708
KVNAGCRLLLREGVP	NEURL3	136	Q96EH8
TLRPRCILGVTQKTI	TIMM21	51	Q9BVV7
KRQEGRVPVLRSCRV	ZNF773	126	Q6PK81
VCVLRKRRLLQPGGG	TOR4A	36	Q9NXH8
LIICVKRRKPRGDVV	TNFRSF14	221	Q92956
QRVCKVIPLAVRGRA	TBC1D28	96	Q2M2D7
KIRRLEGIPICRQHL	ZFAND4	56	Q86XD8
LNTPLGVVRCPRVRK	GTF3C1	1046	Q12789
RVQKIRPSILGCNIL	TXNIP	256	Q9H3M7
ARVPVVVCREKQSGL	TUT7	391	Q5VYS8
CASPRRLANKRIGQI	SLIT1	466	O75093
APQGVTVRCRIIRDK	TULP3	196	O75386
GPGVQVREVKCRVLL	ADAMTSL3	581	P82987
CQRLAAKGRRIPLSE	ADAMTSL3	846	P82987
RGVVCDKRNPNGIRV	KYNU	421	Q16719