Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	positive regulation of CD8-positive, alpha-beta T cell proliferation	PTPN22 HLA-E	3.65e-05	5	40	2	GO:2000566
Domain	-	PSD3 IRS1 BMX RABGAP1 MYO7B ARHGAP21 ITK	2.03e-05	391	41	7	2.30.29.30
Domain	PH_dom-like	PSD3 IRS1 BMX RABGAP1 MYO7B ARHGAP21 ITK	3.52e-05	426	41	7	IPR011993
Domain	PH	PSD3 IRS1 BMX ARHGAP21 ITK	1.39e-04	229	41	5	PF00169
Domain	BTK	BMX ITK	1.68e-04	9	41	2	SM00107
Domain	ZF_BTK	BMX ITK	1.68e-04	9	41	2	PS51113
Domain	Znf_Btk_motif	BMX ITK	1.68e-04	9	41	2	IPR001562
Domain	BTK	BMX ITK	1.68e-04	9	41	2	PF00779
Domain	PH	PSD3 IRS1 BMX ARHGAP21 ITK	3.41e-04	278	41	5	SM00233
Domain	PH_DOMAIN	PSD3 IRS1 BMX ARHGAP21 ITK	3.46e-04	279	41	5	PS50003
Domain	PH_domain	PSD3 IRS1 BMX ARHGAP21 ITK	3.52e-04	280	41	5	IPR001849
Domain	ConA-like_dom	TRIM43B TRIM43 ADGRV1 NRP2	1.33e-03	219	41	4	IPR013320
Domain	GPS	ADGRF3 ADGRV1	2.52e-03	34	41	2	SM00303
Domain	GPS	ADGRF3 ADGRV1	2.67e-03	35	41	2	PF01825
Domain	GPS	ADGRF3 ADGRV1	2.83e-03	36	41	2	PS50221
Domain	PTPc	PTPN22 PTPRB	2.83e-03	36	41	2	SM00194
Domain	GPS	ADGRF3 ADGRV1	2.98e-03	37	41	2	IPR000203
Domain	TYR_PHOSPHATASE_PTP	PTPN22 PTPRB	3.31e-03	39	41	2	PS50055
Domain	G_PROTEIN_RECEP_F2_1	ADGRF3 ADGRV1	3.48e-03	40	41	2	PS00649
Domain	G_PROTEIN_RECEP_F2_3	ADGRF3 ADGRV1	3.48e-03	40	41	2	PS50227
Domain	GPCR_2_extracellular_dom	ADGRF3 ADGRV1	3.48e-03	40	41	2	IPR001879
Domain	PTPase_domain	PTPN22 PTPRB	3.65e-03	41	41	2	IPR000242
Domain	Y_phosphatase	PTPN22 PTPRB	3.65e-03	41	41	2	PF00102
Domain	G_PROTEIN_RECEP_F2_2	ADGRF3 ADGRV1	5.39e-03	50	41	2	PS00650
Domain	7tm_2	ADGRF3 ADGRV1	5.39e-03	50	41	2	PF00002
Domain	PTPc_motif	PTPN22 PTPRB	7.43e-03	59	41	2	SM00404
Domain	Tyr_Pase_cat	PTPN22 PTPRB	7.43e-03	59	41	2	IPR003595
Domain	GPCR_2-like	ADGRF3 ADGRV1	7.68e-03	60	41	2	IPR017981
Domain	GPCR_2_secretin-like	ADGRF3 ADGRV1	7.68e-03	60	41	2	IPR000832
Domain	G_PROTEIN_RECEP_F2_4	ADGRF3 ADGRV1	7.93e-03	61	41	2	PS50261
Pubmed	Genomic cloning and partial characterization of human chymotrypsinogen gene.	CTRB2 CTRB1	1.36e-06	2	41	2	8186414
Pubmed	Chymotrypsin Reduces the Severity of Secretagogue-Induced Pancreatitis in Mice.	CTRB2 CTRB1	1.36e-06	2	41	2	30076839
Pubmed	The CTRB1-CTRB2 risk allele for chronic pancreatitis discovered in European populations does not contribute to disease risk variation in the Chinese population due to near allele fixation.	CTRB2 CTRB1	1.36e-06	2	41	2	28951524
Pubmed	Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis.	CTRB2 CTRB1	1.36e-06	2	41	2	28754779
Pubmed	Sequencing of the complex CTRB1-CTRB2 locus in chronic pancreatitis.	CTRB2 CTRB1	1.36e-06	2	41	2	33036922
Pubmed	Evolutionary relationships between laboratory mice and subspecies of Mus musculus based on the restriction fragment length variants of the chymotrypsin gene at the Prt-2 locus.	CTRB2 CTRB1	1.36e-06	2	41	2	2565717
Pubmed	Molecular cloning and nucleotide sequence of human pancreatic prechymotrypsinogen cDNA.	CTRB2 CTRB1	1.36e-06	2	41	2	2917002
Pubmed	Protein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase A oncogene.	IRS1 BMX SMTNL2	2.31e-06	22	41	3	22305495
Pubmed	Genetic study of pancreatic proteinase in mice (Mus musculus): genetic variants of trypsin and chymotrypsin.	CTRB2 CTRB1	4.06e-06	3	41	2	1008801
Pubmed	Genetic study of pancreatic proteinase in mice (Mus musculus): linkage of the Prt-2 locus on chromosome 8.	CTRB2 CTRB1	4.06e-06	3	41	2	1016231
Pubmed	Evolutionary expansion of polyaspartate motif in the activation peptide of mouse cationic trypsinogen limits autoactivation and protects against pancreatitis.	CTRB2 CTRB1	4.06e-06	3	41	2	34643096
Pubmed	Secretagogue-induced pancreatitis in mice devoid of chymotrypsin.	CTRB2 CTRB1	4.06e-06	3	41	2	38981616
Pubmed	Loss of chymotrypsin-like protease (CTRL) alters intrapancreatic protease activation but not pancreatitis severity in mice.	CTRB2 CTRB1	4.06e-06	3	41	2	32678161
Pubmed	Tacrolimus differentially regulates the proliferation of conventional and regulatory CD4(+) T cells.	PTPN22 ITK	4.06e-06	3	41	2	19714314
Pubmed	SRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactome.	IRS1 BMX ITK	7.36e-06	32	41	3	22974441
Pubmed	The accessory factor Nef links HIV-1 to Tec/Btk kinases in an Src homology 3 domain-dependent manner.	BMX ITK	1.35e-05	5	41	2	24722985
Pubmed	Genetic study of pancreatic proteinase and alpha-amylase in mice (Mus musculus).	CTRB2 CTRB1	1.35e-05	5	41	2	4461036
Pubmed	Genetic and biochemical characterization of a new chymotrypsin isozyme of the house mouse, CTRA-1.	CTRB2 CTRB1	1.35e-05	5	41	2	1820020
Pubmed	Chromosomal assignments of genes for trypsin, chymotrypsin B, and elastase in mouse.	CTRB2 CTRB1	1.35e-05	5	41	2	6589791
Pubmed	Identification of phosphorylation sites within the SH3 domains of Tec family tyrosine kinases.	BMX ITK	1.35e-05	5	41	2	12573241
Pubmed	A family of nonclassical class I MHC genes contributes to ultrasensitive chemodetection by mouse vomeronasal sensory neurons.	NRP2 HLA-E	1.35e-05	5	41	2	24719092
Pubmed	Autoactivation of mouse trypsinogens is regulated by chymotrypsin C via cleavage of the autolysis loop.	CTRB2 CTRB1	2.03e-05	6	41	2	23814066
Pubmed	IRS-1 Functions as a Molecular Scaffold to Coordinate IGF-I/IGFBP-2 Signaling During Osteoblast Differentiation.	IRS1 PTPRB	2.84e-05	7	41	2	26773517
Pubmed	Context-dependent functions of angiopoietin 2 are determined by the endothelial phosphatase VEPTP.	PTPRB NRP2	3.78e-05	8	41	2	29358379
Pubmed	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	ADAD1 PTPN22 HLA-E	4.49e-05	58	41	3	17554300
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	EMC7 RABGAP1 MAN1A1 ZDHHC13 ARHGAP21 LOXL2 NRP2 HLA-E	6.84e-05	1201	41	8	35696571
Pubmed	Altered development of CD8+ T cell lineages in mice deficient for the Tec kinases Itk and Rlk.	ITK HLA-E	7.41e-05	11	41	2	16860760
Pubmed	Characterization of a novel gene, sperm-tail-associated protein (Stap), in mouse post-meiotic testicular germ cells.	CTRB2 CTRB1	1.05e-04	13	41	2	11468771
Pubmed	Trim43a, Trim43b, and Trim43c: Novel mouse genes expressed specifically in mouse preimplantation embryos.	TRIM43B TRIM43	1.41e-04	15	41	2	19703589
Pubmed	A quantitative protein interaction network for the ErbB receptors using protein microarrays.	IRS1 BMX ITK	1.66e-04	90	41	3	16273093
Pubmed	A microarray analysis of the XX Wnt4 mutant gonad targeted at the identification of genes involved in testis vascular differentiation.	CTRB2 CTRB1	2.29e-04	19	41	2	16844427
Pubmed	Gene mapping on mouse chromosome 8 by interspecific crosses: new data on a linkage group conserved on human chromosome 16q.	CTRB2 CTRB1	2.29e-04	19	41	2	2571576
Pubmed	gp 120s derived from four syncytium-inducing HIV-1 strains induce different patterns of CD4 association with lymphocyte surface molecules.	PTPRB HLA-E	2.54e-04	20	41	2	9263011
Pubmed	Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics.	PTPN22 ITK	2.54e-04	20	41	2	31591574
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	FOLH1B WDR45B RABGAP1 ADGRV1 PTPRB ZDHHC13 LOXL2 MYT1	2.99e-04	1489	41	8	28611215
Pubmed	Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.	ADAD1 PTPN22	4.00e-04	25	41	2	21829393
Pubmed	High-resolution mapping of a linkage group on mouse chromosome 8 conserved on human chromosome 16Q.	CTRB2 CTRB1	4.33e-04	26	41	2	9069116
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	SPAG1 GLOD4 FSCN1 DHX29 ARHGAP21	5.14e-04	565	41	5	25468996
Pubmed	The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.	ADGRF3 ADGRV1	5.39e-04	29	41	2	15203201
Pubmed	Genome-wide searching of rare genetic variants in WTCCC data.	ADAD1 PTPN22	6.58e-04	32	41	2	20549515
Pubmed	Zbtb20 is essential for the specification of CA1 field identity in the developing hippocampus.	MAN1A1 NRP2	6.58e-04	32	41	2	20308569
Pubmed	International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.	ADGRF3 ADGRV1	7.00e-04	33	41	2	25713288
Pubmed	Identification of transcripts with enriched expression in the developing and adult pancreas.	CTRB2 REG1B CTRB1 LOXL2 MYT1	8.04e-04	624	41	5	18554416
Pubmed	Abstracts of meeting presentations: Human gene mapping 7, Los Angeles Conference (1983), Seventh International Workshop on Human Gene Mapping.	CTRB2 CTRB1	8.33e-04	36	41	2	6690234
Pubmed	The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis.	CTRB2 CTRB1	8.33e-04	36	41	2	25063451
Pubmed	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	PTPN22 HLA-E	8.80e-04	37	41	2	19430480
Pubmed	Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development.	REG1B NRP2	9.28e-04	38	41	2	31597102
Pubmed	Endothelin-2 deficiency causes growth retardation, hypothermia, and emphysema in mice.	CTRB2 CTRB1	1.08e-03	41	41	2	23676500
Pubmed	NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation.	CTRB2 CTRB1	1.13e-03	42	41	2	37353485
Interaction	CTRB2 interactions	CTRB2 CTRB1	1.09e-05	3	39	2	int:CTRB2
Cytoband	2q11.1	TRIM43B TRIM43	2.90e-04	28	41	2	2q11.1
Cytoband	16q23.1	CTRB2 CTRB1	3.79e-04	32	41	2	16q23.1
Cytoband	8p21.3	PSD3 LOXL2	5.36e-04	38	41	2	8p21.3
Cytoband	Ensembl 112 genes in cytogenetic band chr16q23	CTRB2 CTRB1	4.87e-03	116	41	2	chr16q23
Cytoband	Ensembl 112 genes in cytogenetic band chr10p12	MSRB2 ARHGAP21	7.00e-03	140	41	2	chr10p12
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PSD3 IRS1 BMX ARHGAP21 ITK	1.74e-05	206	29	5	682
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM43B TRIM43	1.01e-02	95	29	2	59
GeneFamily	SH2 domain containing	BMX ITK	1.14e-02	101	29	2	741
ToppCell	normal_Lymph_Node-Myeloid_cells-Activated_DCs\|normal_Lymph_Node / Location, Cell class and cell subclass	PSD3 PRRG4 FSCN1 LOXL2 NRP2	8.44e-07	190	41	5	15978ddd37b521343f88b62dad1643077fc22b2b
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BMX MAN1A1 PTPRB NRP2 HLA-E	8.89e-07	192	41	5	4e63d95f75fe6eb3f817e84528883e95093c5bbd
ToppCell	ASK440-Endothelial\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	BMX PTPRB FSCN1 NRP2 HLA-E	9.59e-07	195	41	5	1cdaab17866a1e5170e0f6bfcc69134425fdd8df
ToppCell	(53)_Lymphoid_DC\|World / shred on Cell_type and subtype	PSD3 FSCN1 ARHGAP21 LOXL2 NRP2	1.32e-06	208	41	5	30212cfacad94a7cc562a69efa73a31259851515
ToppCell	facs-Marrow-KLS-18m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRV1 PTPRB ITK SMTNL2	1.21e-05	154	41	4	37765512dfae557b9f6eb30a29463b93682a4404
ToppCell	facs-Marrow-KLS-24m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRF3 FSCN1 GGN AFG1L	1.51e-05	163	41	4	b83a35c4426d66b5734a98fa6c72b345fe462030
ToppCell	facs-Marrow-KLS-24m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRF3 FSCN1 GGN AFG1L	1.51e-05	163	41	4	c20ca9b6b4170ebcb0e66eef3e5d8ebff22b1a91
ToppCell	356C-Myeloid-Dendritic-cDC_activated\|356C / Donor, Lineage, Cell class and subclass (all cells)	PSD3 FSCN1 LOXL2 NRP2	1.67e-05	167	41	4	43a9375fdbafd7450c553e4620e21537e08639dd
ToppCell	facs-Aorta-Heart-24m-Endothelial-endocardial_endothelial_cells\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM43B BMX GGN SMTNL2	1.71e-05	168	41	4	edbab94f14e16a1a76546a18fe777a183080d1de
ToppCell	droplet-Liver-Npc-18m-Lymphocytic-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN22 ADGRF3 CTRB1 ITK	1.83e-05	171	41	4	872b3b33cd3893d63c45617db0269692430b0e8b
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_10\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PSD3 FSCN1 LOXL2 NRP2	1.91e-05	173	41	4	09a13407a41ff2cba82fc417b72bf9a24ce6c42e
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_10\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PSD3 FSCN1 LOXL2 NRP2	1.91e-05	173	41	4	bfec038a6783f166240da4861e100643c6ea80a5
ToppCell	3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BMX NRP2 HLA-E CRX	2.09e-05	177	41	4	dfaed388926ce050730492a532824af68bf4feff
ToppCell	COVID-19-Heart-Lymph_EC\|Heart / Disease (COVID-19 only), tissue and cell type	MAN1A1 FSCN1 NRP2 HLA-E	2.19e-05	179	41	4	411620201a860716a8773b92f50f7b94ef34a586
ToppCell	VE-matDC-\|VE / Condition, Cell_class and T cell subcluster	PSD3 FSCN1 LOXL2 NRP2	2.28e-05	181	41	4	6252184ef098b911df50be4fe1b5565849a5b6b8
ToppCell	VE-matDC\|VE / Condition, Cell_class and T cell subcluster	PSD3 FSCN1 LOXL2 NRP2	2.28e-05	181	41	4	982fd96ef75bc9ab2c2f4970c01b76ba7a164871
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BMX MAN1A1 NRP2 HLA-E	2.38e-05	183	41	4	a90ffd9c50caa65f537a2e441e37655e1b622327
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BMX MAN1A1 NRP2 HLA-E	2.38e-05	183	41	4	13ad20ec140ef5b96fdace3369b5befc0f40bb76
ToppCell	droplet-Heart-4Chambers-21m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMX PTPRB FSCN1 NRP2	2.44e-05	184	41	4	f17d713af4a97dff4eeeab24c405677ef2ffcf84
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BMX MAN1A1 NRP2 HLA-E	2.49e-05	185	41	4	fb84fcf7f51f53489bcb3962fa9cb483e48257ed
ToppCell	PBMC-Control-cDC_10\|Control / Compartment, Disease Groups and Clusters	PSD3 FSCN1 LOXL2 NRP2	2.49e-05	185	41	4	4b5a7450fed912f340da16065c1e65d626dbe8d1
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BMX MAN1A1 NRP2 HLA-E	2.54e-05	186	41	4	9d250d5ae7cf9129be05b41d70cb6c3a046c5f1e
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BMX FSCN1 NRP2 HLA-E	2.59e-05	187	41	4	65d406122dffe18279f14a1ed35ba091730b97be
ToppCell	390C-Myeloid-Dendritic-cDC_activated\|390C / Donor, Lineage, Cell class and subclass (all cells)	PSD3 FSCN1 LOXL2 NRP2	2.59e-05	187	41	4	60c2576f31a60f819deb9ec500d1f714b469df4e
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BMX FSCN1 NRP2 HLA-E	2.59e-05	187	41	4	4c15c0ed41a55271fc793cb76fee97fa64190369
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BMX FSCN1 NRP2 HLA-E	2.59e-05	187	41	4	5274f2b302bbf7fed30c480af4f35058d2cf61e0
ToppCell	wk_08-11-Endothelial-Lymph_endothelial-Lymphatic_endo\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	BMX PTPRB NRP2 HLA-E	2.76e-05	190	41	4	279c5f68b993dc7adbf9aa69fffb1321cdebc48a
ToppCell	21-Trachea-Endothelial\|Trachea / Age, Tissue, Lineage and Cell class	PTPRB FSCN1 LOXL2 NRP2	2.76e-05	190	41	4	bce09634acbc2cfd53666328e8aed8bf8835f845
ToppCell	wk_08-11-Endothelial-Lymph_endothelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	BMX PTPRB NRP2 HLA-E	2.76e-05	190	41	4	d7f1dc032d161529559e01832d1a3112c6f6cc1a
ToppCell	21-Trachea-Endothelial-Endothelial\|Trachea / Age, Tissue, Lineage and Cell class	PTPRB FSCN1 LOXL2 NRP2	2.76e-05	190	41	4	08437396a98ca9526f69c3a74bbf2929f3c68b8e
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BMX MAN1A1 NRP2 HLA-E	2.88e-05	192	41	4	fa0ef05a32c661bdd59b5a9b6f75fd647ee937f3
ToppCell	367C-Myeloid-Dendritic-cDC_activated\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	PSD3 FSCN1 LOXL2 NRP2	2.88e-05	192	41	4	e44e37e5aeba8628556020d05e1606b28e2faa4f
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_mature_DC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PSD3 PRRG4 FSCN1 ARHGAP21	2.94e-05	193	41	4	d9be4d1de863fffc2240d6fd1a2f8dfb2d2bc916
ToppCell	normal_Lymph_Node-Myeloid_cells-Activated_DCs\|Myeloid_cells / Location, Cell class and cell subclass	PSD3 FSCN1 LOXL2 NRP2	2.94e-05	193	41	4	024d30eb143d8278c0851c3a6c9426226fa3b480
ToppCell	normal_Pleural_Fluid-Myeloid_cells-Activated_DCs\|normal_Pleural_Fluid / Location, Cell class and cell subclass	PSD3 FSCN1 LOXL2 NRP2	3.00e-05	194	41	4	219056d4ad256cda73208b8c570bbf689219df83
ToppCell	facs-Heart-LA-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMX PTPRB FSCN1 NRP2	3.00e-05	194	41	4	33cc4f1d716cb71d54cdedbe9bbdc0d7b17c4777
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-immature_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PTPRB FSCN1 LOXL2 NRP2	3.00e-05	194	41	4	bf8e78d53802ac758be1c3db833779c26a94e1d5
ToppCell	ASK440-Endothelial-Lymphatic\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	BMX FSCN1 NRP2 HLA-E	3.00e-05	194	41	4	4aa68e39e36094359dfbedf1e9bdf3ea5c32ed1a
ToppCell	390C-Myeloid-Dendritic-cDC_activated\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	PSD3 FSCN1 LOXL2 NRP2	3.06e-05	195	41	4	ecf7d9856a5b507ec17c325c9a772dc5a184bc8e
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PTPRB FSCN1 LOXL2 HLA-E	3.06e-05	195	41	4	8ab45ab94c722c4aef0229ee1121cd744bf659dd
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-neuron_precursor\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADGRV1 FSCN1 MYT1 RIMS3	3.18e-05	197	41	4	1378bf90a4b80b8166ef352c282ce51b114ba693
ToppCell	ASK428-Endothelial\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	PTPRB FSCN1 NRP2 HLA-E	3.24e-05	198	41	4	d69d0ff115298596173a4278897a65007a71f5df
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-neuron_precursor-Neuroblast\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADGRV1 FSCN1 MYT1 RIMS3	3.24e-05	198	41	4	c506334d81af672ef9ddc8c4fd2a790bdb58e63e
ToppCell	Parenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	BMX PTPRB MYO7B GGN	3.37e-05	200	41	4	a8b59e6fe04271fef61db911a286b5c48438bb84
ToppCell	Tracheal-10x3prime_v2-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	BMX MAN1A1 FSCN1 NRP2	3.37e-05	200	41	4	35f6c7f2469d12748c27f2a5d4a161ef839b4a07
ToppCell	mLN-Dendritic_cell-Lymphoid_DC\|Dendritic_cell / Region, Cell class and subclass	PSD3 FSCN1 LOXL2 NRP2	3.37e-05	200	41	4	3813fa1ee1462ba83fd8b6253070f46f0b063084
ToppCell	Tracheal-10x3prime_v2-Endothelial-Endothelia_lymphatic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	BMX MAN1A1 FSCN1 NRP2	3.37e-05	200	41	4	b515b2ab0c3f5928dd67f2f227fc932451c272bb
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Vein\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MAN1A1 PTPRB FSCN1 NRP2	3.37e-05	200	41	4	b3f93b71589251197cde96b7bc6d065c106f61cd
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Inmt_(Inmt)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	PTPN22 GGN LOXL2	1.49e-04	112	41	3	ba0bd3a77c4865a71fb92d195cd7459c562b63db
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	PTPN22 GGN LOXL2	1.49e-04	112	41	3	f9a796b4b5e227096ab360ca9ec08b1c564ac1eb
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Inmt_(Inmt)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	PTPN22 GGN LOXL2	1.49e-04	112	41	3	153614f307525af56501ac8f9c357c5f7de7882c
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GLOD4 PTPRB FSCN1	3.26e-04	146	41	3	2d907e50206c4762a8baa741363bc7f0a04bd84e
ToppCell	LPS_only-Hematopoietic_Mast-Mast_cells-T-cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAD1 PTPN22 ITK	3.53e-04	150	41	3	ccb782fbcb3122266354a112a9a850506664f44d
ToppCell	LPS_only-Hematopoietic_Mast-Mast_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAD1 PTPN22 ITK	3.53e-04	150	41	3	7290e9a812b1b2f919e67ccde0acf52687ab138f
ToppCell	LPS_only-Hematopoietic_Mast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAD1 PTPN22 ITK	3.53e-04	150	41	3	2c5078a1f769ba8153dee756b53d28eb7b434a96
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRV1 PTPRB ITK	3.88e-04	155	41	3	c58a5fb8d853f12204e961d633e83452eb12a659
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRV1 PTPRB ITK	3.88e-04	155	41	3	9cb8c42c2e451b2d4dcd7154a4b1bfd21bbb7ea8
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN22 BMX GGN	4.11e-04	158	41	3	91d265e95156f16459924d3e4dd11c180e164eee
ToppCell	facs-Lung-EPCAM-24m-Lymphocytic-CD8+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN22 ITK CRX	4.18e-04	159	41	3	776139481f2d3630461b4dabca606ebf6e6f034e
ToppCell	facs-Lung-EPCAM-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN22 ITK CRX	4.18e-04	159	41	3	bbb19e2f0b7cee70836fa96dc22f888cbc403d28
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRB RIMS3 NRP2	4.18e-04	159	41	3	c960df9e4fa980401941866b5081facac4590b4d
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADAD1 PTPN22 ITK	4.18e-04	159	41	3	8d958d79f5eb3ab683d1245ae7f4f22a2cefbc55
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRB FSCN1 HLA-E	4.26e-04	160	41	3	830e3ef8c9708d25872c3052a0b2682fa9372111
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PTPN22 LOXL2 RIMS3	4.34e-04	161	41	3	d72c572613f8eff3251cb7b1e9dcc76d193b2f21
ToppCell	Children_(3_yrs)-Immune-dendritic_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FSCN1 GGN LOXL2	4.34e-04	161	41	3	cd41abb7ae659d3d314281783a0aaad562b26037
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN22 BMX GGN	4.42e-04	162	41	3	93bd29c52846c3156b8b0d2e39c552373efdfe93
ToppCell	droplet-Fat-Scat-18m-Mesenchymal-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPAG1 IRS1 RIMS3	4.50e-04	163	41	3	1eec7f5e5fed05fa21d3f81db588f10605f08ea7
ToppCell	facs-Marrow-KLS-24m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRF3 FSCN1 GGN	4.58e-04	164	41	3	d2b5f51af7fcffddebe997ee302bacbd85d76852
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPN22 BMX PTPRB	4.66e-04	165	41	3	62457b7b74c6eae42d91d65e7dc6df6bf8e061f7
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BMX RABGAP1 PTPRB	4.74e-04	166	41	3	7a45785a40b7425f97be67bab1c5ceb69b2bd85a
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BMX MAN1A1 HLA-E	4.74e-04	166	41	3	941d6aa94ab9d36e5f6c40f446c926754e070d56
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BMX MAN1A1 HLA-E	4.74e-04	166	41	3	6f5ecf3b2cf613ae0535ab3d21d93622f1497571
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FSCN1 LOXL2 SMTNL2	4.74e-04	166	41	3	d373f1092e85eeb317a7406032b259f11e6adbe0
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FSCN1 LOXL2 SMTNL2	4.74e-04	166	41	3	f453a1d545d59003d98485ac31e85e6cf451817c
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BMX RABGAP1 PTPRB	4.74e-04	166	41	3	bbd382812f8a84a5d99888de2d7cca3a8b5e4695
ToppCell	droplet-Lung-LUNG-30m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM43B FSCN1 GGN	4.91e-04	168	41	3	0e8b0e6399c6c82c9c0e546f7316f902de0765d3
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	BMX FSCN1 NRP2	4.91e-04	168	41	3	dae37b316ce80dfe4236c4ed7f0d4e7c340fa7b6
ToppCell	TCGA-Pancreas\|World / Sample_Type by Project: Shred V9	CTRB2 REG1B CTRB1	4.91e-04	168	41	3	279d5fcf9bd3f56ab560e37eed6fb3bd57dd93de
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)\|368C / Donor, Lineage, Cell class and subclass (all cells)	BMX FSCN1 NRP2	4.91e-04	168	41	3	a74c8a9e3299183fba31ce3053ef325b5dbcd104
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BMX PTPRB NRP2	5.00e-04	169	41	3	58136b8a0bf2dab45c91a053ef7225ea49ccb871
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BMX PTPRB NRP2	5.00e-04	169	41	3	04c6ed38e1d1befba5ef5f37a3c1e045a0b163d6
ToppCell	(7)_MNP-(7)_DC_activated\|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)	PSD3 FSCN1 ARHGAP21	5.08e-04	170	41	3	4ab495b38a071fa8207331df2ce0d78a2dcd034e
ToppCell	ILEUM-non-inflamed-(3)_mature_DC\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PSD3 FSCN1 ARHGAP21	5.08e-04	170	41	3	60151394460e6f27a42fab434e8b7b2adc78b128
ToppCell	356C-Myeloid-Dendritic-cDC_activated\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	PSD3 FSCN1 NRP2	5.08e-04	170	41	3	513d9036aa41d4d902da8baa66a66206abb6f3b0
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_dendritic-mature_conventional_dendritic_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FSCN1 LOXL2 NRP2	5.17e-04	171	41	3	d934d68efc5739483c735dc702ccd30b07a6aa7e
ToppCell	ILEUM-non-inflamed-(3)_MNP-(3)_mature_DC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PSD3 FSCN1 ARHGAP21	5.17e-04	171	41	3	341f9f79c1ed654ab347e25dc4936f89ffdf9617
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BMX PTPRB NRP2	5.26e-04	172	41	3	fc092a0631555d79e00ef9890cbd806e15bca2d4
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BMX PTPRB NRP2	5.26e-04	172	41	3	745725bd10c82017d678463b8fef0d2dcf09a8fd
ToppCell	343B-Fibroblasts-Fibroblast-B_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PSD3 ZC3H3 AFG1L	5.26e-04	172	41	3	c6bc78fd63c9479a84ec0552b55c89750cad0fa5
ToppCell	facs-GAT-Fat-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAD1 PTPN22 ITK	5.26e-04	172	41	3	a9f0ccaca0d83bfec79e3251e346a165c34c242b
ToppCell	Endothelial-B-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	BMX LOXL2 RIMS3	5.26e-04	172	41	3	d4e98ff9c7cbc95457e1d71fa60f151a2f178dae
ToppCell	343B-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PSD3 ZC3H3 AFG1L	5.26e-04	172	41	3	bfb87a281a9cf6ad45b310bf8104fc0ab382b549
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Dendritic-migDC\|lymph-node_spleen / Manually curated celltypes from each tissue	PSD3 FSCN1 NRP2	5.26e-04	172	41	3	1b24bed3cd8e3fa463c5e7cefdf9e99e639e2f84
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAN1A1 PTPRB NRP2	5.26e-04	172	41	3	9a1743abcd5fbd38253ea84d88ad716cfb71de36
ToppCell	Endothelial-B-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	BMX PTPRB FSCN1	5.26e-04	172	41	3	8a527dff06d841a86c7eb04a1dd9630787294da4
ToppCell	367C-Myeloid-Dendritic-cDC_activated\|367C / Donor, Lineage, Cell class and subclass (all cells)	FSCN1 LOXL2 NRP2	5.35e-04	173	41	3	94f99f7e7813d6e53e0bedf97087400b1bf00129
ToppCell	367C-Lymphocytic-ILC-ILC-2\|367C / Donor, Lineage, Cell class and subclass (all cells)	ABHD4 SPAG1 ITK	5.35e-04	173	41	3	0451450605521fecb27a958628870d268adfb023
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAD1 PTPRB HLA-E	5.35e-04	173	41	3	3877cead288ce9509e6cccf57e55ec5e1bd7ce18
ToppCell	facs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l27\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRB FSCN1 MYO7B	5.35e-04	173	41	3	ad9777e4ae70b11676ec735eb6db91776ca0cb19
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM43 IRS1 MYT1	5.44e-04	174	41	3	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
Drug	c189	CTRB2 CTRB1	3.16e-06	2	41	2	CID000248048
Drug	BOCPheONP	CTRB2 CTRB1	3.16e-06	2	41	2	CID000111308
Drug	dansyl-D-arginine methyl ester	CTRB2 CTRB1	3.16e-06	2	41	2	CID000191369
Drug	MPM-06	CTRB2 CTRB1	3.16e-06	2	41	2	CID000161546
Drug	methyl 6-phenylhexanoate	CTRB2 CTRB1	3.16e-06	2	41	2	CID011820300
Drug	NSC-374899	CTRB2 CTRB1	3.16e-06	2	41	2	CID000435726
Drug	5-aminotetrazole	CTRB2 CTRB1	3.16e-06	2	41	2	CID000020467
Drug	2-bromoisobutyric acid	CTRB2 CTRB1	3.16e-06	2	41	2	CID000074924
Drug	p-toluamidine	CTRB2 CTRB1	3.16e-06	2	41	2	CID000122753
Drug	methylbenzenebutanoate	CTRB2 CTRB1	3.16e-06	2	41	2	CID000281254
Drug	N-acetyl-alpha-azaphenylalanine phenyl ester	CTRB2 CTRB1	3.16e-06	2	41	2	CID000191275
Drug	Asp-Arg-Val-Tyr-Val-His-Pro-Phe-His-Leu	CTRB2 CTRB1	3.16e-06	2	41	2	CID004418081
Drug	isobutyl sulfide	CTRB2 CTRB1	3.16e-06	2	41	2	CID000011607
Drug	3-amino-2-pyridone	CTRB2 CTRB1	9.48e-06	3	41	2	CID000322353
Drug	ASA-BMPA	CTRB2 CTRB1	9.48e-06	3	41	2	CID003035649
Drug	p-nitrophenyl benzoate	CTRB2 CTRB1	9.48e-06	3	41	2	CID000070396
Drug	N-acetylbenzotriazole	CTRB2 CTRB1	9.48e-06	3	41	2	CID000087784
Drug	Z-Phe-OMe	CTRB2 CTRB1	9.48e-06	3	41	2	CID003082435
Drug	photophor	CTRB2 CTRB1	9.48e-06	3	41	2	CID000014780
Drug	3-methylcoumarin	CTRB2 CTRB1	9.48e-06	3	41	2	CID000017130
Drug	dibutyl iodomethaneboronate	CTRB2 CTRB1	9.48e-06	3	41	2	CID000098591
Drug	zinc;dipicolinate	CTRB2 CTRB1	9.48e-06	3	41	2	CID004309911
Drug	2-propyl methylphosphonochloridate	CTRB2 CTRB1	9.48e-06	3	41	2	CID000102124
Drug	2-oxobut-3-ynoate	CTRB2 CTRB1	9.48e-06	3	41	2	CID000171547
Drug	AFMeq	CTRB2 CTRB1	9.48e-06	3	41	2	CID000194069
Drug	Bz-Cti-otbu	CTRB2 CTRB1	9.48e-06	3	41	2	CID006452691
Drug	n-(2-oxoethyl)benzamide	CTRB2 CTRB1	9.48e-06	3	41	2	CID000188995
Drug	AC1L49DM	CTRB2 CTRB1	9.48e-06	3	41	2	CID000152933
Drug	FK-316	CTRB2 CTRB1	9.48e-06	3	41	2	CID000133688
Drug	AC1L19T8	CTRB2 CTRB1	9.48e-06	3	41	2	CID000000694
Drug	Marinostatin D	CTRB2 CTRB1	9.48e-06	3	41	2	CID000132206
Drug	c140	CTRB2 CTRB1	9.48e-06	3	41	2	CID002783250
Drug	1FD7	CTRB2 CTRB1	9.48e-06	3	41	2	CID000445579
Drug	Benzamidomethaneboronic acid	CTRB2 CTRB1	9.48e-06	3	41	2	CID000127677
Drug	phenyl hippurate	CTRB2 CTRB1	9.48e-06	3	41	2	CID000076323
Drug	FK-386	CTRB2 CTRB1	9.48e-06	3	41	2	CID000135044
Drug	FK-375	CTRB2 CTRB1	9.48e-06	3	41	2	CID000135042
Drug	carbostyril-124	CTRB2 CTRB1	9.48e-06	3	41	2	CID000088277
Drug	N-trifluoroacetyl-4-fluorophenylalanine	CTRB2 CTRB1	9.48e-06	3	41	2	CID000328214
Drug	Glt-leu-phe-nh-meq	CTRB2 CTRB1	9.48e-06	3	41	2	CID000194914
Drug	AC1L4Z4F	CTRB2 CTRB1	9.48e-06	3	41	2	CID000194913
Drug	Glt-Phe-NH-FMeq	CTRB2 CTRB1	9.48e-06	3	41	2	CID000194912
Drug	C18 4	CTRB2 CTRB1	9.48e-06	3	41	2	CID000077248
Drug	diacetyl trimer	CTRB2 CTRB1	9.48e-06	3	41	2	CID000193527
Drug	FK-448	CTRB2 CTRB1	9.48e-06	3	41	2	CID006917869
Drug	Ac-Phe-OMe	CTRB2 CTRB1	9.48e-06	3	41	2	CID000097805
Drug	taraxastane	CTRB2 CTRB1	9.48e-06	3	41	2	CID006429404
Drug	thiobenzyl N-heptafluorobutyrylanthranilate	CTRB2 CTRB1	9.48e-06	3	41	2	CID000133906
Drug	Phe-phe-ome	CTRB2 CTRB1	9.48e-06	3	41	2	CID000151728
Drug	phenylethaneboronic acid	CTRB2 CTRB1	9.48e-06	3	41	2	CID000065389
Drug	Benzoyl-dl-leucine	CTRB2 CTRB1	1.89e-05	4	41	2	CID000294887
Drug	Acafcek	CTRB2 CTRB1	1.89e-05	4	41	2	CID000197677
Drug	p-fluorobenzenesulfonyl chloride	CTRB2 CTRB1	1.89e-05	4	41	2	CID000009588
Drug	BSSDA	CTRB2 CTRB1	1.89e-05	4	41	2	CID003081106
Drug	B-1,3-od	CTRB2 CTRB1	1.89e-05	4	41	2	CID011971053
Drug	AC1L2HV6	CTRB2 CTRB1	1.89e-05	4	41	2	CID000047328
Drug	dehydromerodesmosine	CTRB2 CTRB1	1.89e-05	4	41	2	CID006443540
Drug	AC1L4X1Z	CTRB2 CTRB1	1.89e-05	4	41	2	CID000193815
Drug	alpha-amyrin palmitate	CTRB2 CTRB1	1.89e-05	4	41	2	CID000185477
Drug	poly-THIQ	CTRB2 CTRB1	1.89e-05	4	41	2	CID006453487
Drug	NSC-676827	CTRB2 CTRB1	1.89e-05	4	41	2	CID000385555
Drug	N-(4-carboxycyclohexylmethyl)-maleimide	CTRB2 CTRB1	1.89e-05	4	41	2	CID011548799
Drug	G2505_sigma	CTRB2 CTRB1	1.89e-05	4	41	2	CID000111098
Drug	6-amino-1,2-benzopyrone	CTRB2 CTRB1	1.89e-05	4	41	2	CID000046152
Drug	nitrophenylethanol	CTRB2 CTRB1	1.89e-05	4	41	2	CID000097851
Drug	Gemfibrozil [25812-30-0]; Up 200; 16uM; MCF7; HT_HG-U133A	PSD3 PRRG4 RABGAP1 MYT1 NRP2	2.62e-05	196	41	5	2277_UP
Drug	7-chloro-4-nitrobenzofuran	CTRB2 CTRB1	3.15e-05	5	41	2	CID000130782
Drug	Ac-Trp-OEt	CTRB2 CTRB1	3.15e-05	5	41	2	CID000304749
Drug	Z-Phe-Leu	CTRB2 CTRB1	3.15e-05	5	41	2	CID000333351
Drug	5'-FSBAzA	CTRB2 CTRB1	3.15e-05	5	41	2	CID000130430
Drug	AC1L3F57	CTRB2 CTRB1	3.15e-05	5	41	2	CID000139565
Drug	apne	CTRB2 CTRB1	3.15e-05	5	41	2	CID000098192
Drug	3,5-dimethylpyrazole-1-carboxamidine	CTRB2 CTRB1	3.15e-05	5	41	2	CID000097525
Drug	Maap-borov	CTRB2 CTRB1	3.15e-05	5	41	2	CID005486914
Drug	2-amino-4,6-dichlorotriazine	CTRB2 CTRB1	3.15e-05	5	41	2	CID000013615
Drug	AC1O52A0	CTRB2 CTRB1	3.15e-05	5	41	2	CID006475891
Drug	allysine aldol	CTRB2 CTRB1	3.15e-05	5	41	2	CID000191270
Drug	diisopropyl	CTRB2 FSCN1 CTRB1	3.71e-05	36	41	3	CID000006589
Drug	octyl isocyanate	CTRB2 CTRB1	4.72e-05	6	41	2	CID000076616
Drug	Asp-Asp-Asp-Asp	CTRB2 CTRB1	4.72e-05	6	41	2	CID004432006
Drug	N-benzoyl-L-tyrosine thiobenzyl ester	CTRB2 CTRB1	4.72e-05	6	41	2	CID000191444
Drug	Leupeptin acid	CTRB2 CTRB1	4.72e-05	6	41	2	CID000189069
Drug	Sri 8835	CTRB2 CTRB1	4.72e-05	6	41	2	CID000479975
Drug	N,N-dimethylglycylbenzocaine	CTRB2 CTRB1	4.72e-05	6	41	2	CID000188251
Drug	N-benzoyltyrosine butylamide	CTRB2 CTRB1	4.72e-05	6	41	2	CID000125261
Drug	D-gluconyl-glycine azide	CTRB2 CTRB1	4.72e-05	6	41	2	CID000194550
Drug	2-azidoatrazine	CTRB2 CTRB1	4.72e-05	6	41	2	CID003032432
Drug	L-659,286	CTRB2 CTRB1	4.72e-05	6	41	2	CID000128954
Drug	bz-Ala-OMe	CTRB2 CTRB1	4.72e-05	6	41	2	CID000023671
Drug	FK480	CTRB2 CTRB1	4.72e-05	6	41	2	CID000132916
Drug	Maap-borof	CTRB2 CTRB1	4.72e-05	6	41	2	CID005492190
Drug	AC1L4DZ7	CTRB2 CTRB1	4.72e-05	6	41	2	CID000155288
Drug	cobalt;(6E)-6-[[2-[[(E)-(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino]ethylamino]methylene]cyclohexa-2,4-dien-1-one;hydrate	CTRB2 CTRB1	4.72e-05	6	41	2	CID011810022
Drug	AC1L1BW9	CTRB2 CTRB1 ITK	5.51e-05	41	41	3	CID000001636
Drug	dinonylnaphthalene	CTRB2 CTRB1	6.61e-05	7	41	2	CID003015220
Drug	m-aminobenzamidine	CTRB2 CTRB1	6.61e-05	7	41	2	CID000197789
Drug	methyl p-nitrobenzenesulfonate	CTRB2 CTRB1	6.61e-05	7	41	2	CID000022582
Drug	AAPCK	CTRB2 CTRB1	6.61e-05	7	41	2	CID000128055
Drug	Z-Phe-OH	CTRB2 CTRB1	6.61e-05	7	41	2	CID000070878
Drug	Es 8891	CTRB2 CTRB1	6.61e-05	7	41	2	CID000195623
Disease	level of chymotrypsinogen B2 in blood serum	CTRB2 CTRB1	1.61e-06	2	38	2	OBA_2041192
Disease	chymotrypsinogen B measurement	CTRB2 CTRB1	4.84e-06	3	38	2	EFO_0801477
Disease	trypsin-2 measurement	CTRB2 CTRB1	8.82e-05	11	38	2	EFO_0008305
Disease	type 1 diabetes mellitus	CTRB2 ADAD1 PTPN22 CTRB1	2.62e-04	242	38	4	MONDO_0005147
Disease	gamma-glutamyltyrosine measurement	ARHGAP21 RIMS3	5.55e-04	27	38	2	EFO_0021144
Disease	pancreatitis (biomarker_via_orthology)	CTRB2 CTRB1	1.16e-03	39	38	2	DOID:4989 (biomarker_via_orthology)
Disease	grey matter volume measurement	PSD3 NPS	1.48e-03	44	38	2	EFO_0005420
Disease	cervical carcinoma	ADGRV1 MYT1 HLA-E	1.66e-03	182	38	3	EFO_0001061
Disease	HMG CoA reductase inhibitor use measurement	PSD3 CTRB2 CTRB1	1.85e-03	189	38	3	EFO_0009932
Disease	atrophic macular degeneration, age-related macular degeneration, wet macular degeneration	CTRB2 ARHGAP21	2.73e-03	60	38	2	EFO_0001365, EFO_0004683, EFO_1001492
Disease	cholangiocarcinoma (is_marker_for)	PRRG4 FSCN1	3.10e-03	64	38	2	DOID:4947 (is_marker_for)
Disease	BMI-adjusted waist-hip ratio, physical activity measurement	CTRB2 CTRB1	3.59e-03	69	38	2	EFO_0007788, EFO_0008002
Disease	age-related macular degeneration, COVID-19	CTRB2 ARHGAP21	3.59e-03	69	38	2	EFO_0001365, MONDO_0100096
Disease	Drugs used in diabetes use measurement	CTRB2 PTPN22 CTRB1	4.30e-03	255	38	3	EFO_0009924
Disease	gut microbiome measurement, bone density	RABGAP1 NPS	4.56e-03	78	38	2	EFO_0003923, EFO_0007874
Disease	body weight	FOLH1B IRS1 RABGAP1 MAN1A1 ADGRV1 AFG1L	5.14e-03	1261	38	6	EFO_0004338
Disease	hypothyroidism	PTPN22 MYT1 ITK	5.80e-03	284	38	3	EFO_0004705

Protein segments in the cluster

Peptide	Gene	Start	Entry
PWSVSYDGGSAKTIL	CA3	46	P07451
TTGWGKTKYNANKTP	CTRB2	156	Q6GPI1
YTAAWSPGEGSKASS	ADGRF3	366	Q8IZF5
YVSSVGTKFPVKWSA	BMX	566	P51813
ATVYWSLKPSGFNSK	ADGRV1	686	Q8WXG9
GKPFWKAYTVQTSES	AFG1L	41	Q8WV93
IYGSDTWIDTSTGKK	ABHD4	286	Q8TB40
KTITTPTGWSSESYG	ADAD1	31	Q96M93
NFDYTARSWTGKSPK	DHX29	366	Q7Z478
FWCYPVPSSKVSGKS	NPS	21	P0C0P6
YFSSWPPSGTSSKMS	PTPN22	536	Q9Y2R2
GKSSDGKSYVITGSW	RABGAP1	371	Q9Y3P9
SGDSWKTYSKPIFGS	PTPRB	1336	P23467
GKGGSYSKAEWSDSA	HLA-E	336	P13747
TEDSFSKPYDGKWSK	GLOD4	56	Q9HC38
KSWTASSSYGKGEGP	LOXL2	106	Q9Y4K0
YESWTKKSPSPEFSG	FOLH1B	186	Q9HBA9
GSGAPSTDKEKSWLY	NRP2	846	O60462
YTTFPGSKPKFDWVS	GGN	341	Q86UU5
SNAVPSGTSYGKLWT	IRS1	686	P35568
KDSTGKYWTVGSDSA	FSCN1	426	Q16658
KSSSGLTYIAEWKGG	MAN1A1	451	P33908
KSSGPPSYFIKRESW	EMC7	141	Q9NPA0
SLEFKDPTGTWKFTY	CRX	266	O43186
TTGWGKTKYNANKTP	CTRB1	156	P17538
GSLVSYKSWDTGSPS	REG1B	116	P48304
QYTSSTGTKFPVKWA	ITK	511	Q08881
KSSLIWSYPAGSLTF	TRIM43	421	Q96BQ3
TGWYKLFPTSSVADS	RIMS3	271	Q9UJD0
ASASFLPKYFSSKWS	WDR45B	271	Q5MNZ6
SSKWSFSKFQVPSGS	WDR45B	281	Q5MNZ6
GSAPSKYKWKASSPS	ZC3H3	371	Q8IXZ2
FYKTWATDPGFTKAS	ZDHHC13	391	Q8IUH4
PLFSSEKKYCSGTGW	MSRB2	96	Q9Y3D2
EKKYCSGTGWPSFSE	MSRB2	101	Q9Y3D2
YPSLWGFGTTKTFKI	SPAG1	6	Q07617
WSVPSSGYGAVTASK	SMTNL2	251	Q2TAL5
AFWQEYSAKGPTTKS	PRRG4	91	Q9BZD6
KSSLIWSYPAGSLTF	TRIM43B	421	A6NCK2
TKSKGSWGSGKDQYS	ARHGAP21	1391	Q5T5U3
SIYTKGTPEIAFWGS	PSD3	531	Q9NYI0
LTTYPFTKISSWSSG	MYO7B	2046	Q6PIF6
GSSFSWKSLKNEGPT	MYT1	931	Q01538