Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontranslation activator activity

DAZ4 DAZ1 DAZ3 DAZ2

1.45e-0715664GO:0008494
GeneOntologyBiologicalProcessfemale meiosis II

DAZ4 DAZ1 DAZ3 DAZ2

1.43e-096664GO:0007147
GeneOntologyBiologicalProcessmeiosis II

DAZ4 DAZ1 DAZ3 DAZ2

1.43e-096664GO:0007135
GeneOntologyBiologicalProcessmeiosis II cell cycle process

DAZ4 DAZ1 DAZ3 DAZ2

1.43e-096664GO:0061983
GeneOntologyBiologicalProcesspositive regulation of meiotic nuclear division

DAZ4 DAZ1 DAZ3 DAZ2

1.36e-0626664GO:0045836
GeneOntologyBiologicalProcesspositive regulation of translational initiation

DAZ4 DAZ1 DAZ3 DAZ2

2.14e-0629664GO:0045948
GeneOntologyBiologicalProcess3'-UTR-mediated mRNA stabilization

DAZ4 DAZ1 DAZ3 DAZ2

2.82e-0631664GO:0070935
GeneOntologyBiologicalProcesspositive regulation of meiotic cell cycle

DAZ4 DAZ1 DAZ3 DAZ2

5.83e-0637664GO:0051446
GeneOntologyBiologicalProcessoogenesis

KMT2D DAZ4 DAZ1 DAZ3 DAZ2 MAJIN

1.06e-05156666GO:0048477
GeneOntologyBiologicalProcessregulation of meiotic nuclear division

DAZ4 DAZ1 DAZ3 DAZ2

1.29e-0545664GO:0040020
GeneOntologyBiologicalProcessoocyte maturation

DAZ4 DAZ1 DAZ3 DAZ2

1.54e-0547664GO:0001556
GeneOntologyBiologicalProcessoocyte development

KMT2D DAZ4 DAZ1 DAZ3 DAZ2

1.63e-0599665GO:0048599
GeneOntologyBiologicalProcessoocyte differentiation

KMT2D DAZ4 DAZ1 DAZ3 DAZ2

1.98e-05103665GO:0009994
GeneOntologyBiologicalProcessfemale meiotic nuclear division

DAZ4 DAZ1 DAZ3 DAZ2

2.31e-0552664GO:0007143
GeneOntologyBiologicalProcessfemale gamete generation

KMT2D DAZ4 DAZ1 DAZ3 DAZ2 MAJIN

7.90e-05223666GO:0007292
GeneOntologyBiologicalProcesspositive regulation of nuclear division

DAZ4 DAZ1 DAZ3 DAZ2

9.80e-0575664GO:0051785
GeneOntologyBiologicalProcessmRNA stabilization

DAZ4 DAZ1 DAZ3 DAZ2

1.09e-0477664GO:0048255
GeneOntologyBiologicalProcessmeiotic nuclear division

DAZ4 C9orf78 DAZ1 DAZ3 DAZ2 MAJIN

1.18e-04240666GO:0140013
GeneOntologyBiologicalProcessregulation of meiotic cell cycle

DAZ4 DAZ1 DAZ3 DAZ2

1.39e-0482664GO:0051445
GeneOntologyBiologicalProcessnegative regulation of mRNA catabolic process

DAZ4 DAZ1 DAZ3 DAZ2

1.74e-0487664GO:1902373
GeneOntologyBiologicalProcessRNA stabilization

DAZ4 DAZ1 DAZ3 DAZ2

1.82e-0488664GO:0043489
GeneOntologyBiologicalProcessregulation of translational initiation

DAZ4 DAZ1 DAZ3 DAZ2

2.07e-0491664GO:0006446
GeneOntologyBiologicalProcessmeiotic cell cycle process

DAZ4 C9orf78 DAZ1 DAZ3 DAZ2 MAJIN

2.15e-04268666GO:1903046
GeneOntologyBiologicalProcessregulation of T cell differentiation in thymus

RASGRP1 TESPA1 SOS2

2.25e-0437663GO:0033081
GeneOntologyBiologicalProcessnegative regulation of RNA catabolic process

DAZ4 DAZ1 DAZ3 DAZ2

3.09e-04101664GO:1902369
GeneOntologyBiologicalProcessT cell differentiation in thymus

RASGRP1 GLI3 TESPA1 SOS2

4.90e-04114664GO:0033077
GeneOntologyBiologicalProcessnegative regulation of mRNA metabolic process

DAZ4 DAZ1 DAZ3 DAZ2

5.06e-04115664GO:1903312
GeneOntologyBiologicalProcesspositive regulation of reproductive process

DAZ4 DAZ1 DAZ3 DAZ2

5.58e-04118664GO:2000243
GeneOntologyBiologicalProcessregulation of T cell activation

RASGRP1 CD2 GLI3 PDPK1 TMIGD2 TESPA1 SOS2

6.40e-04458667GO:0050863
GeneOntologyBiologicalProcesspositive regulation of T cell differentiation in thymus

RASGRP1 TESPA1

7.69e-0413662GO:0033089
GeneOntologyBiologicalProcessregulation of T cell differentiation

RASGRP1 CD2 GLI3 TESPA1 SOS2

7.84e-04226665GO:0045580
GeneOntologyBiologicalProcesstranslational initiation

DAZ4 DAZ1 DAZ3 DAZ2

8.50e-04132664GO:0006413
GeneOntologyBiologicalProcessgerm cell development

KMT2D DAZ4 TTLL5 DAZ1 DAZ3 DAZ2 MAJIN

8.63e-04482667GO:0007281
GeneOntologyBiologicalProcessmeiotic cell cycle

DAZ4 C9orf78 DAZ1 DAZ3 DAZ2 MAJIN

8.82e-04350666GO:0051321
DomainNUT

NUTM2F NUTM2G

1.15e-045642IPR024310
DomainNUT_N

NUTM2F NUTM2G

1.15e-045642IPR024309
DomainNUT

NUTM2F NUTM2G

1.15e-045642PF12881
DomainZnf_FYVE_PHD

KMT2D PHF20L1 PCLO BRPF1 RPH3A

1.48e-04147645IPR011011
DomainRasGEFN

RASGRP1 SOS2

2.11e-0320642SM00229
DomainSynaptotagmin

PCLO RPH3A

2.11e-0320642IPR001565
DomainRasGEF_N

RASGRP1 SOS2

2.33e-0321642PF00618
DomainEPHD

KMT2D BRPF1

2.55e-0322642PS51805
DomainRas-like_Gua-exchang_fac_N

RASGRP1 SOS2

2.55e-0322642IPR000651
DomainRASGEF_NTER

RASGRP1 SOS2

2.55e-0322642PS50212
DomainRASGEF

RASGRP1 SOS2

3.56e-0326642PS00720
Domain-

KMT2D PHF20L1 PCLO BRPF1 RNF19B RPH3A

4.32e-034496463.30.40.10
DomainZF_PHD_1

KMT2D PHF20L1 BRPF1

4.37e-0396643PS01359
DomainRASGEF_CAT

RASGRP1 SOS2

4.42e-0329642PS50009
DomainRasGEF

RASGRP1 SOS2

4.73e-0330642PF00617
Domain-

RASGRP1 SOS2

4.73e-03306421.10.840.10
DomainRas_GEF_dom

RASGRP1 SOS2

4.73e-0330642IPR023578
DomainRASGEF_cat_dom

RASGRP1 SOS2

4.73e-0330642IPR001895
DomainRasGEF

RASGRP1 SOS2

4.73e-0330642SM00147
DomainZnf_RING/FYVE/PHD

KMT2D PHF20L1 PCLO BRPF1 RNF19B RPH3A

4.80e-03459646IPR013083
DomainIg_V-set

CD2 PILRA TMIGD2 ROBO1

4.83e-03199644IPR013106
DomainRRM_1

DAZ4 DAZ1 DAZ3 DAZ2

5.64e-03208644PF00076
DomainRRM

DAZ4 DAZ1 DAZ3 DAZ2

6.54e-03217644SM00360
DomainRRM_dom

DAZ4 DAZ1 DAZ3 DAZ2

7.64e-03227644IPR000504
DomainRRM

DAZ4 DAZ1 DAZ3 DAZ2

7.99e-03230644PS50102
PathwayWP_OVARIAN_INFERTILITY

DAZ4 DAZ1 DAZ3 DAZ2

3.33e-0635424MM15948
PathwayREACTOME_INTEGRIN_SIGNALING

RASGRP1 PDPK1 APBB1IP

6.84e-0527423M760
PathwayREACTOME_INTEGRIN_SIGNALING

RASGRP1 PDPK1 APBB1IP

7.65e-0528423MM14958
PathwayREACTOME_PLATELET_AGGREGATION_PLUG_FORMATION

RASGRP1 PDPK1 APBB1IP

1.93e-0438423MM15456
PathwayREACTOME_PLATELET_AGGREGATION_PLUG_FORMATION

RASGRP1 PDPK1 APBB1IP

2.09e-0439423M10735
PathwayWP_MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY

SATB2 KMT2D DAZ4 DAZ1 DAZ3 DAZ2

2.48e-04301426MM15983
Pubmed

Analysis of the DAZ gene family in cryptorchidism and idiopathic male infertility.

DAZ4 DAZ1 DAZ3 DAZ2

1.26e-11467415066457
Pubmed

Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene.

DAZ4 DAZ1 DAZ3 DAZ2

1.26e-1146747670487
Pubmed

Impact of partial DAZ1/2 deletion and partial DAZ3/4 deletion on male infertility.

DAZ4 DAZ1 DAZ3 DAZ2

1.26e-11467426232607
Pubmed

Male infertility, genetic analysis of the DAZ genes on the human Y chromosome and genetic analysis of DNA repair.

DAZ4 DAZ1 DAZ3 DAZ2

1.26e-11467411694340
Pubmed

The human DAZ genes, a putative male infertility factor on the Y chromosome, are highly polymorphic in the DAZ repeat regions.

DAZ4 DAZ1 DAZ3 DAZ2

1.26e-1146749321470
Pubmed

Polymorphic expression of DAZ proteins in the human testis.

DAZ4 DAZ1 DAZ3 DAZ2

1.26e-11467419223287
Pubmed

Male infertility caused by a de novo partial deletion of the DAZ cluster on the Y chromosome.

DAZ4 DAZ1 DAZ3 DAZ2

1.26e-11467411095434
Pubmed

[Microdeletion of chromosome Y in male infertility: role of the DAZ gene].

DAZ4 DAZ1 DAZ3 DAZ2

1.26e-11467411688365
Pubmed

Polymorphic DAZ gene family in polymorphic structure of AZFc locus: Artwork or functional for human spermatogenesis?

DAZ4 DAZ1 DAZ3 DAZ2

1.26e-11467412752250
Pubmed

A novel approach for the analysis of DAZ gene copy number in severely idiopathic infertile men.

DAZ4 DAZ1 DAZ3 DAZ2

1.26e-11467411883873
Pubmed

Four DAZ genes in two clusters found in the AZFc region of the human Y chromosome.

DAZ4 DAZ1 DAZ3 DAZ2

1.26e-11467410936047
Pubmed

[Study on DAZ gene copy deletion in severe oligozoospermia sperm donor for ICSI].

DAZ4 DAZ1 DAZ3 DAZ2

1.26e-11467416963411
Pubmed

Partial DAZ deletions in a family with five infertile brothers.

DAZ4 DAZ1 DAZ3 DAZ2

1.26e-11467412801575
Pubmed

Wdr62 is involved in female meiotic initiation via activating JNK signaling and associated with POI in humans.

DAZ4 DAZ1 DAZ3 DAZ2 WDR62

4.50e-111467530102701
Pubmed

Mouse Dazl and its novel splice variant functions in translational repression of target mRNAs in embryonic stem cells.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-11567423298641
Pubmed

Connecting cis-elements and trans-factors with mechanisms of developmental regulation of mRNA translation in meiotic and haploid mammalian spermatogenic cells.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-11567423579190
Pubmed

DAZL is essential for stress granule formation implicated in germ cell survival upon heat stress.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-11567422223682
Pubmed

Kinked β-strands mediate high-affinity recognition of mRNA targets by the germ-cell regulator DAZL.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-11567422021443
Pubmed

The mouse Dazla gene encodes a cytoplasmic protein essential for gametogenesis.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-1156749288969
Pubmed

The dazzle in germ cell differentiation.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-11567420008336
Pubmed

Co-culture of spermatogonial stem cells with sertoli cells in the presence of testosterone and FSH improved differentiation via up-regulation of post meiotic genes.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-11567423456578
Pubmed

Isolation of a mouse homolog of the human DAZ (Deleted in Azoospermia) gene.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-1156748679003
Pubmed

A human DAZ transgene confers partial rescue of the mouse Dazl null phenotype.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-11567410393944
Pubmed

The human autosomal gene DAZLA: testis specificity and a candidate for male infertility.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-1156748968756
Pubmed

A SPGY copy homologous to the mouse gene Dazla and the Drosophila gene boule is autosomal and expressed only in the human male gonad.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-1156748968755
Pubmed

DAZL Regulates Germ Cell Survival through a Network of PolyA-Proximal mRNA Interactions.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-11567430380414
Pubmed

Regulated Formation of an Amyloid-like Translational Repressor Governs Gametogenesis.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-11567426411291
Pubmed

In vivo and in vitro analysis of homodimerisation activity of the mouse Dazl1 protein.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-11567410903443
Pubmed

Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-11567423223451
Pubmed

Somatic cell-derived BMPs induce premature meiosis in male germ cells during the embryonic stage by upregulating Dazl expression.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-11567434985827
Pubmed

Identification of target messenger RNA substrates for the murine deleted in azoospermia-like RNA-binding protein.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-11567411804965
Pubmed

Gene sequence, localization, and evolutionary conservation of DAZLA, a candidate male sterility gene.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-1156749143498
Pubmed

Expression profiling of the developing testis in wild-type and Dazl knockout mice.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-11567414648873
Pubmed

Bisphenol A exposure modifies DNA methylation of imprint genes in mouse fetal germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-11567422699882
Pubmed

A murine homologue of the human DAZ gene is autosomal and expressed only in male and female gonads.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-1156748845845
Pubmed

The DAZ gene cluster on the human Y chromosome arose from an autosomal gene that was transposed, repeatedly amplified and pruned.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-1156748896558
Pubmed

DAZ family proteins exist throughout male germ cell development and transit from nucleus to cytoplasm at meiosis in humans and mice.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-11567411058556
Pubmed

AZFc partial deletions in Chilean men with severe spermatogenic failure.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-11567417416365
Pubmed

Dazl promotes germ cell differentiation from embryonic stem cells.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-11567419783541
Pubmed

Retinoic acid regulates germ cell differentiation in mouse embryonic stem cells through a Smad-dependent pathway.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-11567422293198
Pubmed

DAZL protein expression in mouse preimplantation embryo.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-11567417761180
Pubmed

Dazl functions in maintenance of pluripotency and genetic and epigenetic programs of differentiation in mouse primordial germ cells in vivo and in vitro.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-11567419468308
Pubmed

Evolution of the DAZ gene family suggests that Y-linked DAZ plays little, or a limited, role in spermatogenesis but underlines a recent African origin for human populations.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-1156749700189
Pubmed

Partial rescue of the Dazl knockout mouse by the human DAZL gene.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-11567412200456
Pubmed

Nature of the spermatogenic arrest in Dazl -/- mice.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-11567411514340
Pubmed

Decreased oocyte DAZL expression in mice results in increased litter size by modulating follicle-stimulating hormone-induced follicular growth.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-11567421270429
Pubmed

Loss of oocytes in Dazl knockout mice results in maintained ovarian steroidogenic function but altered gonadotropin secretion in adult animals.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-11567411089564
Pubmed

Mouse autosomal homolog of DAZ, a candidate male sterility gene in humans, is expressed in male germ cells before and after puberty.

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-1156748661148
Pubmed

The RNA-binding protein DAZL functions as repressor and activator of mRNA translation during oocyte maturation.

DAZ4 DAZ1 DAZ3 DAZ2

1.88e-10667432170089
Pubmed

Expression profiles of the DAZ gene family in human testis with and without spermatogenic failure.

DAZ4 DAZ1 DAZ3 DAZ2

1.88e-10667415066460
Pubmed

Dazl binds in vivo to specific transcripts and can regulate the pre-meiotic translation of Mvh in germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

1.88e-10667416278232
Pubmed

Aged mouse ovaries possess rare premeiotic germ cells that can generate oocytes following transplantation into a young host environment.

DAZ4 DAZ1 DAZ3 DAZ2

1.88e-10667420157580
Pubmed

DAZL binds to the transcripts of several Tssk genes in germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

1.88e-10667418452650
Pubmed

A gene trap mutation of a murine homolog of the Drosophila stem cell factor Pumilio results in smaller testes but does not affect litter size or fertility.

DAZ4 DAZ1 DAZ3 DAZ2

1.88e-10667417219433
Pubmed

Mono-butyl phthalate-induced mouse testis injury is associated with oxidative stress and down-regulated expression of Sox9 and Dazl.

DAZ4 DAZ1 DAZ3 DAZ2

1.88e-10667428496037
Pubmed

DAZL regulates Tet1 translation in murine embryonic stem cells.

DAZ4 DAZ1 DAZ3 DAZ2

1.88e-10667426077710
Pubmed

The DAZL family proteins are PABP-binding proteins that regulate translation in germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

1.88e-10667416001084
Pubmed

Cracd Marks the First Wave of Meiosis during Spermatogenesis and Is Mis-Expressed in Azoospermia Mice.

DAZ4 DAZ1 DAZ3 DAZ2

1.88e-10667432962040
Pubmed

Translation of the synaptonemal complex component Sycp3 is enhanced in vivo by the germ cell specific regulator Dazl.

DAZ4 DAZ1 DAZ3 DAZ2

1.88e-10667417526644
Pubmed

Genetic mapping of a male germ cell-expressed gene Tpx-2 to mouse chromosome 17.

DAZ4 DAZ1 DAZ3 DAZ2

1.88e-1066741869307
Pubmed

A gene family required for human germ cell development evolved from an ancient meiotic gene conserved in metazoans.

DAZ4 DAZ1 DAZ3 DAZ2

1.88e-10667411390979
Pubmed

A developmental stage-specific switch from DAZL to BOLL occurs during fetal oogenesis in humans, but not mice.

DAZ4 DAZ1 DAZ3 DAZ2

1.88e-10667424086306
Pubmed

BOULE, a Deleted in Azoospermia Homolog, Is Recruited to Stress Granules in the Mouse Male Germ Cells.

DAZ4 DAZ1 DAZ3 DAZ2

1.88e-10667427632217
Pubmed

The mouse male germ cell-specific gene Tpx-1: molecular structure, mode of expression in spermatogenesis, and sequence similarity to two non-mammalian genes.

DAZ4 DAZ1 DAZ3 DAZ2

1.88e-1066741638086
Pubmed

Spermatogenesis in testes of Dazl null mice after transplantation of wild-type germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

1.88e-10667414611632
Pubmed

DAZL binds to 3'UTR of Tex19.1 mRNAs and regulates Tex19.1 expression.

DAZ4 DAZ1 DAZ3 DAZ2

1.88e-10667419247806
Pubmed

DAZL is a master translational regulator of murine spermatogenesis.

DAZ4 DAZ1 DAZ3 DAZ2

1.88e-10667431355046
Pubmed

The fate of granulosa cells following premature oocyte loss and the development of ovarian cancers.

DAZ4 DAZ1 DAZ3 DAZ2

1.88e-10667423417416
Pubmed

The RNA-binding specificity of the mouse Dazl protein.

DAZ4 DAZ1 DAZ3 DAZ2

4.38e-10767411410654
Pubmed

Identification of a novel gene, DZIP (DAZ-interacting protein), that encodes a protein that interacts with DAZ (deleted in azoospermia) and is expressed in embryonic stem cells and germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

4.38e-10767415081113
Pubmed

Sertoli-cell-specific knockout of connexin 43 leads to multiple alterations in testicular gene expression in prepubertal mice.

DAZ4 DAZ1 DAZ3 DAZ2

4.38e-10767422699423
Pubmed

Characterization of the mouse Dazap1 gene encoding an RNA-binding protein that interacts with infertility factors DAZ and DAZL.

DAZ4 DAZ1 DAZ3 DAZ2

4.38e-10767411604102
Pubmed

Identification of two novel proteins that interact with germ-cell-specific RNA-binding proteins DAZ and DAZL1.

DAZ4 DAZ1 DAZ3 DAZ2

4.38e-10767410857750
Pubmed

The Dazh gene is expressed in male and female embryonic gonads before germ cell sex differentiation.

DAZ4 DAZ1 DAZ3 DAZ2

4.38e-1076749588208
Pubmed

DAZL and CPEB1 regulate mRNA translation synergistically during oocyte maturation.

DAZ4 DAZ1 DAZ3 DAZ2

4.38e-10767426826184
Pubmed

Dazl can bind to dynein motor complex and may play a role in transport of specific mRNAs.

DAZ4 DAZ1 DAZ3 DAZ2

4.38e-10767416946704
Pubmed

Fanconi anemia complementation group C is required for proliferation of murine primordial germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

8.75e-10867410951504
Pubmed

Single-cell transcriptomics reveal temporal dynamics of critical regulators of germ cell fate during mouse sex determination.

DAZ4 DAZ1 DAZ3 DAZ2

8.75e-10867433749946
Pubmed

Hypomethylating therapy in an aggressive stroma-rich model of pancreatic carcinoma.

DAZ4 DAZ1 DAZ3 DAZ2

8.75e-10867423204224
Pubmed

Requirement of the 3'-UTR-dependent suppression of DAZL in oocytes for pre-implantation mouse development.

DAZ4 DAZ1 DAZ3 DAZ2

8.75e-10867429883445
Pubmed

Mouse dead end1 acts with Nanos2 and Nanos3 to regulate testicular teratoma incidence.

DAZ4 DAZ1 DAZ3 DAZ2

8.75e-10867432339196
Pubmed

A mammalian germ cell-specific RNA-binding protein interacts with ubiquitously expressed proteins involved in splice site selection.

DAZ4 DAZ1 DAZ3 DAZ2

8.75e-10867410823932
Pubmed

Embryonic poly(A)-binding protein (EPAB) is required for oocyte maturation and female fertility in mice.

DAZ4 DAZ1 DAZ3 DAZ2

8.75e-10867422621333
Pubmed

DAZL mediates a broad translational program regulating expansion and differentiation of spermatogonial progenitors.

DAZ4 DAZ1 DAZ3 DAZ2

8.75e-10867432686646
Pubmed

A preliminary report on the implication of RT-PCR detection of DAZ, RBMY1, USP9Y and Protamine-2 mRNA in testicular biopsy samples from azoospermic men.

DAZ4 DAZ1 DAZ3 DAZ2

8.75e-10867411869379
Pubmed

A Gene Regulatory Program for Meiotic Prophase in the Fetal Ovary.

DAZ4 DAZ1 DAZ3 DAZ2

1.57e-09967426378784
Pubmed

Dazl deficiency leads to embryonic arrest of germ cell development in XY C57BL/6 mice.

DAZ4 DAZ1 DAZ3 DAZ2

1.57e-09967416310179
Pubmed

Embryoid bodies from mouse stem cells express oxytocin receptor, Oct-4 and DAZL.

DAZ4 DAZ1 DAZ3 DAZ2

1.57e-09967419695304
Pubmed

The epigenetic modifications and the anterior to posterior characterization of meiotic entry during mouse oogenesis.

DAZ4 DAZ1 DAZ3 DAZ2

1.57e-09967428235998
Pubmed

Opposing effects of retinoic acid and FGF9 on Nanos2 expression and meiotic entry of mouse germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

1.57e-09967420159962
Pubmed

Mice with Y chromosome deletion and reduced Rbm genes on a heterozygous Dazl1 null background mimic a human azoospermic factor phenotype.

DAZ4 DAZ1 DAZ3 DAZ2

2.62e-091067410601091
Pubmed

Analysis of Uncharacterized mKiaa1211 Expression during Mouse Development and Cardiovascular Morphogenesis.

DAZ4 DAZ1 DAZ3 DAZ2

2.62e-091067431234534
Pubmed

Tesmin transcription is regulated differently during male and female meiosis.

DAZ4 DAZ1 DAZ3 DAZ2

2.62e-091067414648882
Pubmed

MAX controls meiotic entry in sexually undifferentiated germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

2.62e-091067438433229
Pubmed

Knockout mouse model and gametogenic failure.

DAZ4 DAZ1 DAZ3 DAZ2

2.62e-09106749922113
Pubmed

SYCP3-like X-linked 2 is expressed in meiotic germ cells and interacts with synaptonemal complex central element protein 2 and histone acetyltransferase TIP60.

DAZ4 DAZ1 DAZ3 DAZ2

2.62e-091067423810942
Pubmed

The CDY-related gene family: coordinated evolution in copy number, expression profile and protein sequence.

DAZ4 DAZ1 DAZ3 DAZ2

2.62e-091067412837688
Pubmed

NANOS2 suppresses the cell cycle by repressing mTORC1 activators in embryonic male germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

4.11e-091167434401671
Pubmed

Retinoic acid activates two pathways required for meiosis in mice.

DAZ4 DAZ1 DAZ3 DAZ2

6.15e-091267425102060
Pubmed

ZGLP1 is a determinant for the oogenic fate in mice.

DAZ4 DAZ1 DAZ3 DAZ2

6.15e-091267432054698
CytobandYq11.223

DAZ4 DAZ1 DAZ3 DAZ2

1.10e-0593674Yq11.223
CoexpressionTESAR_JAK_TARGETS_MOUSE_ES_D3_DN

DAZ4 DAZ1 DAZ3 DAZ2

1.68e-0812654MM742
CoexpressionSASAI_TARGETS_OF_CXCR6_AND_PTCH1_DN

DAZ4 DAZ1 DAZ3 DAZ2

1.68e-0812654MM781
CoexpressionWAGSCHAL_EHMT2_TARGETS_UP

DAZ4 DAZ1 DAZ3 DAZ2

2.94e-0723654MM1293
CoexpressionMATZUK_SPERMATOGONIA

DAZ4 DAZ1 DAZ3 DAZ2

1.03e-0631654MM765
CoexpressionCHEN_ETV5_TARGETS_TESTIS

DAZ4 DAZ1 DAZ3 DAZ2

1.33e-0633654MM701
CoexpressionHE_LIM_SUN_FETAL_LUNG_C1_INTERM_NEUROENDOCRINE_CELL

THSD4 HIVEP3 CLIP3 C21orf58 PCLO DEPP1 ROBO1

4.53e-06268657M45696
CoexpressionMADAN_DPPA4_TARGETS

DAZ4 DAZ1 DAZ3 DAZ2

6.28e-0586654MM1312
CoexpressionJACKSON_DNMT1_TARGETS_UP

DAZ4 DAZ1 DAZ3 DAZ2

8.52e-0593654MM1185
CoexpressionGSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_2H_ACT_CD4_TCELL_UP

PCED1B RASGRP1 PHF20L1 MMP16 TESPA1

1.31e-04197655M4211
CoexpressionGSE411_UNSTIM_VS_400MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_DN

HIVEP3 FCHSD2 LMF2 TTLL5 RNF19B

1.37e-04199655M6003
CoexpressionGSE27786_NKTCELL_VS_ERYTHROBLAST_DN

PHACTR4 LRRC56 GAL3ST4 WDR62 SERTAD3

1.40e-04200655M4867
CoexpressionGSE8868_SPLEEN_VS_INTESTINE_CD11B_POS_CD11C_NEG_DC_UP

PCED1B SATB2 ZYX SERTAD3 SOS2

1.40e-04200655M5772
CoexpressionMCCABE_BOUND_BY_HOXC6

THSD4 ZNF536 FCHSD2 DAZ4 DAZ1 DAZ3 DAZ2

1.44e-04461657M6376
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000_k-means-cluster#1

CCDC88C CLIP3 ZNF536 PHF20L1 GLI3 PCLO ZNF629

1.56e-05259667Facebase_RNAseq_e8.5_Floor Plate_1000_K1
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_500_k-means-cluster#3

CCDC88C CLIP3 ZNF536 PCLO ZNF629

3.32e-05118665Facebase_RNAseq_e8.5_Floor Plate_500_K3
CoexpressionAtlasCD positive, CD4 Control, 4+ 8- B220-, Spleen, avg-4

PCED1B RASGRP1 CD2 KMT2D PHF20L1 TESPA1

4.83e-05210666GSM403995_500
CoexpressionAtlasCD positive, CD4 Control, 4+8-B220-, Spleen, avg-2

PCED1B RASGRP1 CD2 KMT2D PHF20L1 TESPA1

6.91e-05224666GSM403994_500
ToppCellhuman_hepatoblastoma-NK.T_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

PCED1B HIVEP3 CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

1.40e-0818867771b7599e7e1d63cc0c8518c0501533755951d58f
ToppCellFetal_29-31_weeks-Immune-T_lymphocyte-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PCED1B CCDC88C RASGRP1 CD2 TMIGD2 TESPA1 APBB1IP

1.62e-0819267792f141d5ac462f652f405efa73ac6ef751f40ea3
ToppCellFetal_29-31_weeks-Immune-T_lymphocyte|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PCED1B CCDC88C RASGRP1 CD2 TMIGD2 TESPA1 APBB1IP

1.62e-0819267769a2b04f03a1b82d067018379f7b8a116e954040
ToppCellhuman_hepatoblastoma-NK.T_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

PCED1B HIVEP3 CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

1.74e-08194677997b02a22d7c89a8fd5615bb79a2a8a34fc3fee6
ToppCellLPS-IL1RA-Lymphocytic_NKT-T_cells-T-cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCED1B RASGRP1 CD2 TMIGD2 TESPA1 APBB1IP

2.27e-07171676539ea88acc6f948efdeae8b69e5c5ffaee29f1d9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CD2 C21orf58 TMIGD2 TESPA1 APBB1IP WDR62

2.27e-0717167655c7bf7211587fa08df13c0a4ff5b78a85d5439e
ToppCellLPS-IL1RA-Lymphocytic_NKT-T_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCED1B RASGRP1 CD2 TMIGD2 TESPA1 APBB1IP

2.35e-071726760fc692be845d4225ff8b63bf9195724fc8510c2c
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_NKT-T_cells-T-cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCED1B RASGRP1 CD2 TMIGD2 TESPA1 APBB1IP

2.69e-071766769d4a4dfeebb5a8a0f3ab18c37c8ddc2cd2158575
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_NKT-T_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCED1B RASGRP1 CD2 TMIGD2 TESPA1 APBB1IP

2.69e-07176676bb41e9478373726eb460af764de0277b2d09928e
ToppCellLPS-antiTNF-Lymphocytic_NKT-T_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCED1B RASGRP1 CD2 TMIGD2 TESPA1 APBB1IP

2.69e-07176676ea27e18407b8a13e8212830da859efeb8f158690
ToppCellLPS-antiTNF-Lymphocytic_NKT-T_cells-T-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCED1B RASGRP1 CD2 TMIGD2 TESPA1 APBB1IP

2.69e-07176676bfbab3c5b738b3b0b1540f2059d0245fbd8c0031
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_NKT|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCED1B RASGRP1 CD2 TMIGD2 TESPA1 APBB1IP

2.78e-07177676f1efd9c3074d5635700fe7fbebf3dd0b1e0a84f1
ToppCellLPS-antiTNF-Lymphocytic_NKT|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCED1B RASGRP1 CD2 TMIGD2 TESPA1 APBB1IP

2.98e-07179676ecea75c568911ff56939c9f67ab901497bd4356c
ToppCellLPS_only-Lymphocytic_NKT-T_cells-T-cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCED1B RASGRP1 CD2 TMIGD2 TESPA1 APBB1IP

3.07e-07180676dcef253f2e97e4436b1b04e8a06a53ff6e64522c
ToppCellCOVID-19-T_cells-Tregs|COVID-19 / group, cell type (main and fine annotations)

PCED1B CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

3.18e-07181676534659cf754326c6a73c0daa30e9d610612a0292
ToppCellLPS_only-Lymphocytic_NKT-T_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCED1B RASGRP1 CD2 TMIGD2 TESPA1 APBB1IP

3.18e-07181676a4347ae554e6dcf03c7001a2b69332b377c7c034
ToppCellControl-T_cells|Control / group, cell type (main and fine annotations)

PCED1B CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

3.85e-07187676f4e8e0eba58da89b56587667555a5d4754e108c7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SATB2 KANK1 AFF2 ABI3BP MICAL3 APBB1IP

4.09e-071896763b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCellFetal_29-31_weeks-Immune-T_lymphocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PCED1B CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

4.22e-071906762a8de1cf27a9ebc3825cf9e7a489ecd064dfc7f9
ToppCellControl-T_cells-CD4+_T_cells|Control / group, cell type (main and fine annotations)

PCED1B CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

4.22e-071906760733be5e54fe15d6d6ea51c154a95258e83f1b92
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-T_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PCED1B CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

4.22e-0719067607ea0578ca0561077557203ae660530f53fc4067
ToppCellwk_08-11-Hematologic_Lymphocytic-NK|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PCED1B RASGRP1 CD2 TMIGD2 TESPA1 APBB1IP

4.22e-0719067686b0d142b7d1a3b35580edd104f947106be2c9c6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-T_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PCED1B CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

4.22e-071906765b4b3eed7aa798bb7e3c5e968c8dc4144e377a5f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PCED1B CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

4.35e-0719167696a7179a845d3daa046ed71fa45c51255f130a7f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PCED1B CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

4.77e-07194676633fe72cc8a489abde12428e326478409ca03263
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PCED1B CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

4.77e-0719467687a86df0b542f287b0b20f4a4b1a37002271671d
ToppCellImmune-T_lymphocyte|World / Lineage, Cell type, age group and donor

PCED1B CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

4.77e-07194676f47fa18c87b35a3960557f8169ff7830dd6ecb80
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HIVEP3 CCDC88C RASGRP1 CD2 C9orf78 TESPA1

4.92e-07195676cab90c67a7b3119c0d0d2d5e84511c41dcb8765f
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PCED1B CCDC88C RASGRP1 CD2 KATNAL1 TESPA1

5.06e-07196676c9fb81a0578db6d278b8582d7b3add6c407e6dcf
ToppCellcontrol-CD8+_T_naive|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PCED1B RASGRP1 CD2 TMIGD2 ROBO1 TESPA1

5.54e-071996766a61ce7404c65e506091fee99a2001f5a9b39f31
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PCED1B CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

5.70e-07200676c6c2b39359c65c9444987d02d1c899dff2ad1366
ToppCellLPS-IL1RA-Lymphocytic_NKT-T_cells-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCED1B CD2 TMIGD2 TESPA1 APBB1IP

1.44e-06128675c2045f052cc713e52312eb015825711576fcb6c5
ToppCellControl-T_cells-Tregs|Control / group, cell type (main and fine annotations)

PCED1B CCDC88C RASGRP1 CD2 APBB1IP

5.64e-06169675e1e0983f31ec81b3fad5f9c6140d17f03f81a5dc
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-NK_T_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RASGRP1 TMIGD2 CCDC57 TESPA1 APBB1IP

6.87e-061766751ea45cf7b7e12206c3eca1594173368643c50e59
ToppCellControl-Lymphocytic_NKT-T_cells-T-cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RASGRP1 CD2 TMIGD2 TESPA1 APBB1IP

7.25e-06178675910f8bea19d335455aba24e6a07b4834b709db5d
ToppCellLPS-IL1RA-Lymphocytic_NKT|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RASGRP1 CD2 TMIGD2 TESPA1 APBB1IP

7.45e-061796755ccf0824611ded5c673d94dff3048aedac12f1a8
ToppCellControl-Lymphocytic_NKT-T_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RASGRP1 CD2 TMIGD2 TESPA1 APBB1IP

7.45e-06179675d892d9496f1c33e23312092591eb2e968e736f7d
ToppCellwk_08-11-Hematologic_Lymphocytic-T_&_ILC-ILC3|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

RASGRP1 CD2 TMIGD2 TESPA1 APBB1IP

7.87e-06181675bf2bd5ecec1e23a44f719d7efeb1f45d6c1c6b32
ToppCellLV-17._Lymphocyte|LV / Chamber and Cluster_Paper

PCED1B CCDC88C CD2 TESPA1 APBB1IP

7.87e-0618167581fafa69c8c240250a667a5f3b321e8be1b9a288
ToppCellwk_08-11-Hematologic_Lymphocytic-T_&_ILC-ILCP|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

RASGRP1 CD2 TMIGD2 TESPA1 APBB1IP

8.30e-06183675797eb968c57e48db33ff8e2236ee22e9425c4676
ToppCellwk_08-11-Hematologic_Lymphocytic-T_&_ILC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

RASGRP1 CD2 TMIGD2 TESPA1 APBB1IP

8.52e-0618467551ae0963b4fb034c3f605ee4e5da513cba7aca35
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PCED1B RASGRP1 CD2 TMIGD2 TESPA1

8.52e-061846755350b58aa9979631228835d11eb45ddf81d08bff
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GXYLT2 GLI3 TTLL5 ROBO1 MMP16

8.75e-061856751b990e3089772be2b38c6d7ea0d1bf22461ae3ea
ToppCellControl-T_cells-CD8+_T_cells|Control / group, cell type (main and fine annotations)

PCED1B CCDC88C RASGRP1 CD2 APBB1IP

8.75e-0618567502ab64c0166c0646d1d4c6ed110ef0b75a1096d0
ToppCell10x3'2.3-week_14-16-Lymphocytic_T-T_NK-CD4_T_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PCED1B RASGRP1 CD2 TMIGD2 TESPA1

8.75e-0618567532f43ddc8a899827924834546db33928e353271b
ToppCell15-Distal-Immune-Hematopoietic,_T_Cells|Distal / Age, Tissue, Lineage and Cell class

PCED1B RASGRP1 CD2 TMIGD2 TESPA1

8.75e-06185675481e3d3b63f2e5b4783088523c3cf70a461aed27
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

8.98e-061866759d576dce2c5deefef1adda16c6da7055c8d57f8f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

8.98e-06186675bd3bd022b575d9b0ef90d50a5cb874085a827b77
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

8.98e-06186675924cc357b4c4ce8e9b05773bdab544f0b65474cc
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THSD4 ZNF536 ABI3BP TTLL5 PHACTR4

9.45e-061886756468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THSD4 ZNF536 ABI3BP TTLL5 PHACTR4

9.45e-061886757a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THSD4 ZNF536 ABI3BP TTLL5 PHACTR4

9.45e-061886759cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellLPS_only-Lymphocytic_NKT|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCED1B RASGRP1 CD2 TMIGD2 APBB1IP

9.45e-06188675bbe65b1c11c88ab62d8485cfc3a913ff9da89aad
ToppCellwk_08-11-Hematologic_Lymphocytic-NK-Intermediate_NK|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PCED1B RASGRP1 CD2 TMIGD2 APBB1IP

9.45e-06188675a8170e4ce6406af9f5ad5317e6e26efa7bc66411
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

9.70e-06189675b87d586a9570fa54f3e0c6bd4731c5badcaedae6
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PCED1B CCDC88C RASGRP1 CD2 TESPA1

9.70e-06189675d05e043d0874b8563b9f5514f6c884b35c603e3a
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

9.70e-06189675823d6debd09e440ddf36c54af24a5f20e222a21e
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

9.70e-0618967547c2b419b081d5bf75da5e3d9a0e05a70362dfe7
ToppCellCF-Lymphoid-B_cell|CF / Disease state, Lineage and Cell class

PCED1B CCDC88C RASGRP1 CCDC50 MICAL3

9.95e-06190675374d8fd63c733178acab07682ed1519693efab45
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PCED1B CCDC88C CD2 TESPA1 APBB1IP

9.95e-06190675ba61f04fd38efae01f721ba616252d1372ff1002
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PCED1B CCDC88C CD2 TESPA1 APBB1IP

9.95e-061906755a37568000dfc33fcbb59b578c1963fb7cf872ec
ToppCell10x5'v1-week_14-16-Lymphocytic_T-T_NK-CD4_T_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PCED1B RASGRP1 CD2 TMIGD2 TESPA1

9.95e-061906758fdf35c2ad1d325c00c00e4fcf2506341ff14537
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-SELL+_CD8_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCDC88C CD2 TMIGD2 CCDC57 TESPA1

9.95e-06190675d83fdc352ebb0c2f2a7c2138bf6e3b7a8ce83a6a
ToppCellFetal_29-31_weeks-Immune-T_lymphocyte-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RASGRP1 CD2 TMIGD2 TESPA1 APBB1IP

1.02e-05191675133864ec1e89f97a82c3bb01d2a3c658397fefaf
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

1.02e-05191675d9506b88d806aadd4c2b9bf86fe994c47799e7f6
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

1.02e-05191675b42c54308abe1241cc38ddce96b9d38d07983891
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PCED1B RASGRP1 CD2 TMIGD2 TESPA1

1.02e-05191675d9a6f61fcda4f5352488f7f55cb9b57aeacc717f
ToppCellCOVID-19-lung-CD4+_Treg|COVID-19 / Disease (COVID-19 only), tissue and cell type

CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

1.02e-051916755a4ad5ae5c2dbfb225158cb598ef649c26a48350
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SATB2 KANK1 AFF2 MICAL3 APBB1IP

1.02e-051916751cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCell10x3'2.3-week_17-19-Myeloid_DC-DC-pDC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PCED1B FCHSD2 TMIGD2 CCDC50 RPH3A

1.02e-05191675faf4de97003a938a243b0101456913c2b0e1804f
ToppCellChildren_(3_yrs)-Immune-T_lymphocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

1.02e-05191675c7be771543089fc94e5c62fd22f745189642aec3
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PCED1B RASGRP1 CD2 TMIGD2 TESPA1

1.02e-05191675696921a4f160b6b55698652488ed781e855e5e51
ToppCellCOVID-19-T_cells-CD4+_T_cells|COVID-19 / group, cell type (main and fine annotations)

CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

1.02e-051916750646cca78e24aeb6baa9934d3c439b797c567997
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

1.02e-051916759aabbc65430e2233b8f2d3fff9face7807b88b48
ToppCellCOVID-19-T_cells|COVID-19 / group, cell type (main and fine annotations)

CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

1.02e-051916757f64add931b64b8d35836fa6bee9ebab593844d3
ToppCellCOVID-19-lung-CD4+_Treg|lung / Disease (COVID-19 only), tissue and cell type

CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

1.02e-0519167573ea3078c1f55cd47e4d99e77b3ce4ff17549d49
ToppCellNS-critical-d_07-13-Lymphoid-Treg|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PCED1B RASGRP1 CD2 TMIGD2 TESPA1

1.05e-05192675cd34defac6565d34db507918e791b09c79f7d1f8
ToppCellNS-moderate-d_16-33-Lymphoid-Treg|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RASGRP1 CD2 TMIGD2 TESPA1 APBB1IP

1.05e-0519267548d557071bad80edd3ec6e5ad8dcd97037da9553
ToppCellmoderate-Lymphoid-Treg|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RASGRP1 CD2 TMIGD2 TESPA1 APBB1IP

1.05e-05192675e370ff5aaff7b7042ba9aaf93de43aa563b8b9f9
ToppCell18-Distal-Immune-Hematopoietic,_T_Cells|Distal / Age, Tissue, Lineage and Cell class

PCED1B CD2 TMIGD2 TESPA1 APBB1IP

1.05e-051926757538c7f63108f357478ea4c5bf27c1f9825b87c7
ToppCellwk_15-18-Hematologic_Lymphocytic-T_&_ILC-CD8_T|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PCED1B RASGRP1 CD2 TMIGD2 TESPA1

1.05e-05192675375817f1b813d7b2be10738c05611e1d1ba23055
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PCED1B RASGRP1 CD2 TMIGD2 TESPA1

1.07e-0519367595f5611dd9583f339b7c9f52bb478af204fb89ad
ToppCellCOVID-19-lung-CD4+_T_cells_metabolically_active|COVID-19 / Disease (COVID-19 only), tissue and cell type

CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

1.07e-05193675326fd2ce2c4b51e5a38f2a7a09f22f8f0e92735a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

1.07e-0519367512f1333f11e6c262954ad7912d8fd2962ab06d25
ToppCellCOVID-19-kidney-T-cells-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

1.07e-051936755b84fa640cf30dea55fde53b810f850ff946d253
ToppCellCF-Lymphoid|CF / Disease state, Lineage and Cell class

PCED1B CCDC88C RASGRP1 CCDC50 MICAL3

1.07e-0519367511de07d13a7da223990b56fa89ba7fc1c3dd0122
ToppCellChildren_(3_yrs)-Immune-T_lymphocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

1.07e-05193675b9769b45125d2244afe53f9f71c92c04ddccf980
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-Activated_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RASGRP1 CD2 TMIGD2 TESPA1 APBB1IP

1.10e-051946756385cf2a1529d2e225e407c33da959fccaaca3a4
ToppCellChildren_(3_yrs)-Immune-T_lymphocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CCDC88C RASGRP1 CD2 TESPA1 APBB1IP

1.10e-051946753d6f2d190dd50804afea299957cc44c2bb756134
ToppCellBAL-Control-Lymphocyte-T/NK-CD4+_T|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CCDC88C RASGRP1 CD2 TMIGD2 TESPA1

1.10e-05194675a7f11ac46965b3fc21c9d04870ce0bd2b3868cec
ToppCellsevere_COVID-19-CD4+_T_naive|severe_COVID-19 / disease group, cell group and cell class (v2)

PCED1B RASGRP1 CD2 TMIGD2 TESPA1

1.10e-051946754b86f3cc173ea779399d5b3598b45b25f60a4395
ToppCellcritical-Lymphoid-Treg|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PCED1B RASGRP1 CD2 TMIGD2 TESPA1

1.10e-05194675deaae292972371b6afae58a023fe2fc05b351bda
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PCED1B CCDC88C RASGRP1 CD2 TESPA1

1.13e-051956754b9663509cc5e3f409f6d0d37640cb301a827d98
ToppCell10x_3'_v3-blood_(10x_3'_v3)-lymphocytic-T_lymphocytic-naive_thymus-derived_CD4-positive,_alpha-beta_T_cell|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PCED1B RASGRP1 CD2 KANK1 TESPA1

1.13e-051956754e114f6399863406bd87220dea7fb7dfd08824bd
ToppCell10x3'2.3-week_14-16-Lymphocytic_T-T_NK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PCED1B RASGRP1 CD2 TMIGD2 TESPA1

1.13e-05195675146e482f660c0f234a3d15495ad9e7ed7b88fdc8
ToppCell15-Airway-Immune-Hematopoietic,_T_Cells|Airway / Age, Tissue, Lineage and Cell class

RASGRP1 CD2 TMIGD2 TESPA1 APBB1IP

1.13e-05195675ec392fc8bd2c0f1e3a79f2e401608fd6ba8d339c
ToppCellwk_08-11-Hematologic_Lymphocytic|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

RASGRP1 CD2 TMIGD2 TESPA1 APBB1IP

1.13e-051956757f6ff1180c0be199c63dd049700d62dbc792b347
ToppCell10x3'2.3-week_14-16-Lymphocytic_T|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PCED1B RASGRP1 CD2 TMIGD2 TESPA1

1.13e-05195675efc71886b8521539dcba9d5c1a8304eec2dc6c42
ToppCell10x5'v1-week_14-16-Lymphocytic_T-T_NK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PCED1B RASGRP1 CD2 TMIGD2 TESPA1

1.16e-05196675cd23c6a29ead3f3ec23c871e6e30bb8812bf1973
ToppCell10x5'v1-week_14-16-Lymphocytic_T|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PCED1B RASGRP1 CD2 TMIGD2 TESPA1

1.16e-051966756fb93466e53a12f8292da29b9e4952d453b913c3
Drugboron trichloride

DAZ4 DAZ1 DAZ3 DAZ2

9.62e-106664CID000025135
Drugd-gluconhydroximo-1,5-lactam

AFF2 DAZ4 DAZ1 DAZ3 DAZ2

2.81e-0831665CID000003479
DrugMimosine [500-44-7]; Down 200; 20.2uM; PC3; HT_HG-U133A

HIVEP3 LMF2 PLEKHG6 GAL3ST4 SNAPC4 MMP16 TESPA1 SOS2

9.79e-081966686703_DN
DrugLoxapine succinate [27833-64-3]; Down 200; 9uM; PC3; HT_HG-U133A

HIVEP3 CCDC88C LMF2 PDPK1 GAL3ST4 SNAPC4 MMP16 TESPA1

1.02e-071976686694_DN
Drugdesmethylazelastine

DAZ4 DAZ1 DAZ3 DAZ2

1.14e-0716664CID000162558
Drugdazmegrel

DAZ4 DAZ1 DAZ3 DAZ2

2.42e-0719664CID000053555
DrugYM 026

DAZ4 DAZ1 DAZ3 DAZ2

2.42e-0719664CID000004443
DrugAZFd

DAZ4 DAZ1 DAZ3 DAZ2

5.47e-0723664CID000196489
Drugdansylaziridine

DAZ4 DAZ1 DAZ3 DAZ2

5.47e-0723664CID000104008
DrugVistar

DAZ4 DAZ1 DAZ3 DAZ2

3.54e-0636664CID000040896
Drug3-bromo-7-nitroindazole

DAZ4 DAZ1 DAZ3 DAZ2

3.54e-0636664CID000001649
Drugmolybdenum disulfide

DAZ4 DAZ1 DAZ3 DAZ2

7.30e-0643664CID000014823
Drug2-chlorodideoxyadenosine

DAZ4 DAZ1 DAZ3 DAZ2

7.30e-0643664CID000072194
Drugpropham

DAZ4 DAZ1 DAZ3 DAZ2

8.01e-0644664CID000024685
Drugridogrel

DAZ4 DAZ1 DAZ3 DAZ2

1.57e-0552664CID005362391
DrugEpicatechin-(-) [154-23-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A

LMF2 TTLL5 RNF19B UBXN6 DENND2B WDR62

2.23e-051966662815_UP
DrugHydralazine hydrochloride [304-20-1]; Down 200; 20.4uM; PC3; HT_HG-U133A

HIVEP3 PLEKHG6 TTLL5 GAL3ST4 TESPA1 SOS2

2.23e-051966663724_DN
Drugazafagomine

DAZ4 DAZ1 DAZ3 DAZ2

2.27e-0557664CID011957435
DrugNadide [53-84-9]; Down 200; 6uM; MCF7; HT_HG-U133A

LMF2 RNF19B UBXN6 ROBO1 SNAPC4 SOS2

2.29e-051976667227_DN
DrugStreptomycin sulfate [3810-74-0]; Down 200; 2.8uM; MCF7; HT_HG-U133A

LMF2 AFF2 PHF20L1 PDPK1 TTLL5 RNF19B

2.29e-051976667194_DN
DrugC75; Up 200; 10uM; PC3; HT_HG-U133A

CCDC88C SATB2 DEPP1 GAL3ST4 WDR62 SOS2

2.36e-051986666428_UP
DrugSulfanilamide [63-74-1]; Up 200; 23.2uM; MCF7; HT_HG-U133A

LMF2 PLEKHG6 PILRA TTLL5 WDR62 SOS2

2.43e-051996663449_UP
DrugCatechin-(+,-) hydrate [7295-85-4]; Up 200; 13.8uM; PC3; HT_HG-U133A

THSD4 AFF2 GAL3ST4 MMP16 CCDC57 WDR62

2.43e-051996664255_UP
DrugNSC56408

DAZ4 DAZ1 DAZ3 DAZ2

3.17e-0562664CID000005604
Drugkt S

DAZ4 DAZ1 DAZ3 DAZ2

4.05e-0566664CID006399216
Drugazelastine

DAZ4 DAZ1 DAZ3 DAZ2

6.36e-0574664CID000002267
Drugp11-13

DAZ4 DAZ1 DAZ3 DAZ2

6.71e-0575664CID000015759
DrugBW755C

DAZ4 DAZ1 DAZ3 DAZ2

1.55e-0493664CID000047795
Drugbipy

DAZ4 DAZ1 DAZ3 DAZ2

1.82e-0497664CID000001474
Drug5224221; Down 200; 12uM; MCF7; HT_HG-U133A_EA

CCDC88C PLEKHG6 PHF20L1 MMP16 SOS2

2.06e-04186665839_DN
DrugFelodipine [72509-76-3]; Up 200; 10.4uM; MCF7; HT_HG-U133A

PNPLA2 PCLO RNF19B WDR62 SOS2

2.11e-041876655294_UP
DrugPhenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A

FCHSD2 GLI3 PHACTR4 MMP16 WDR62

2.16e-041886656451_DN
DrugFenbufen [36330-85-5]; Down 200; 15.8uM; PC3; HT_HG-U133A

TANC2 HIVEP3 ABI3BP MMP16 SOS2

2.33e-041916654279_DN
DrugDexamethasone acetate [1177-87-3]; Up 200; 9.2uM; PC3; HT_HG-U133A

TANC2 DEPP1 GAL3ST4 SNAPC4 DENND2B

2.44e-041936652079_UP
DrugDoxycycline hydrochloride [10592-13-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A

PDPK1 UBXN6 SNAPC4 ZYX SOS2

2.44e-041936653479_DN
DrugAndrosterone [53-41-8]; Down 200; 13.8uM; MCF7; HT_HG-U133A

PHF20L1 GLI3 PHACTR4 MMP16 SOS2

2.50e-041946655696_DN
DrugAlsterpaullone; Up 200; 10uM; MCF7; HT_HG-U133A

LMF2 INTS1 GAL3ST4 SNAPC4 WDR62

2.50e-041946657051_UP
DrugTenoxicam [59804-37-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A

THSD4 HIVEP3 DEPP1 GAL3ST4 TESPA1

2.50e-041946654182_UP
DrugDirithromycin [62013-04-1]; Down 200; 4.8uM; MCF7; HT_HG-U133A

RNF19B UBXN6 SNAPC4 MFSD10 SOS2

2.50e-041946657446_DN
DrugMethylergometrine maleate [113-42-8]; Up 200; 8.8uM; MCF7; HT_HG-U133A

PNPLA2 UBXN6 MMP16 ZYX WDR62

2.50e-041946655303_UP
Drug(R)-Propranolol hydrochloride [13071-11-9]; Down 200; 13.6uM; PC3; HT_HG-U133A

HIVEP3 LMF2 MICAL3 SNAPC4 SERTAD3

2.56e-041956655814_DN
Drugpioglitazone HCl; Down 200; 10uM; PC3; HT_HG-U133A

ABI3BP TTLL5 MMP16 WDR62 SOS2

2.56e-041956655977_DN
DrugBambuterol hydrochloride [81732-46-9]; Down 200; 10uM; MCF7; HT_HG-U133A

PNPLA2 FCHSD2 PHF20L1 RNF19B WDR62

2.56e-041956657239_DN
DrugDelcorine; Up 200; 8.4uM; MCF7; HT_HG-U133A

CD2 AFF2 IL25 TTLL5 WDR62

2.56e-041956653613_UP
DrugDoxylamine succinate [562-10-7]; Down 200; 10.2uM; PC3; HT_HG-U133A

HIVEP3 RNF19B SNAPC4 ZYX SOS2

2.56e-041956654235_DN
DrugTetrandrine [518-34-3]; Down 200; 6.4uM; MCF7; HT_HG-U133A

FCHSD2 LMF2 SNAPC4 MMP16 SOS2

2.56e-041956656082_DN
DrugVinpocetine [42971-09-5]; Up 200; 11.4uM; MCF7; HT_HG-U133A

PNPLA2 AFF2 GAL3ST4 MMP16 TESPA1

2.62e-041966657213_UP
DrugQuinidine hydrochloride monohydrate [6151-40-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A

CCDC88C PNPLA2 KANK1 PHACTR4 UBXN6

2.62e-041966656267_DN
DrugMesoridazine besylate [32672-69-8]; Down 200; 7.4uM; MCF7; HT_HG-U133A

CCDC88C FCHSD2 TTLL5 MFSD10 SOS2

2.62e-041966657017_DN
DrugForskolin, from Coleus forskohlii; Down 200; 0.5uM; MCF7; HT_HG-U133A

SEMA6B LMF2 RNF19B MMP16 SOS2

2.62e-041966657055_DN
Drugestradiol, USP; Down 200; 0.01uM; ssMCF7; HG-U133A

LMF2 PHF20L1 PDPK1 GAL3ST4 SNAPC4

2.62e-04196665373_DN
DrugEvoxine [522-11-2]; Down 200; 11.6uM; HL60; HT_HG-U133A

PNPLA2 PILRA RNF19B MICAL3 SOS2

2.62e-041966652186_DN
DrugAceclofenac [89796-99-6]; Up 200; 11.2uM; PC3; HT_HG-U133A

HIVEP3 RNF19B SNAPC4 MMP16 SERTAD3

2.62e-041966657269_UP
Drugclozapine; Down 200; 10uM; MCF7; HT_HG-U133A

CCDC88C FCHSD2 SATB2 ZYX WDR62

2.62e-041966656988_DN
Drug(d,l)-Tetrahydroberberine [522-97-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A

HIVEP3 PNPLA2 RNF19B UBXN6 ZYX

2.62e-041966652818_UP
DrugSulfinpyrazone [57-96-5]; Down 200; 9.8uM; MCF7; HT_HG-U133A

HIVEP3 TTLL5 RNF19B UBXN6 DENND2B

2.62e-041966653192_DN
DrugMiconazole [22916-47-8]; Down 200; 9.6uM; MCF7; HT_HG-U133A

SATB2 LMF2 PDPK1 MMP16 WDR62

2.69e-041976651477_DN
Drugnifedipine; Up 200; 10uM; MCF7; HG-U133A

PNPLA2 CD2 KMT2D GAL3ST4 APBB1IP

2.69e-04197665335_UP
DrugBenzethonium chloride [121-54-0]; Down 200; 9uM; MCF7; HT_HG-U133A

LMF2 GLI3 BRPF1 SNAPC4 WDR62

2.69e-041976657207_DN
DrugPhenazopyridine hydrochloride [136-40-3]; Down 200; 16uM; MCF7; HT_HG-U133A

FCHSD2 LMF2 MMP16 ZYX WDR62

2.69e-041976656100_DN
DrugRoxithromycin [80214-83-1]; Up 200; 4.8uM; HL60; HT_HG-U133A

KMT2D PILRA TTLL5 MMP16 RPH3A

2.69e-041976652992_UP
DrugProgesterone [57-83-0]; Up 200; 12.8uM; MCF7; HT_HG-U133A

SEMA6B HIVEP3 ABI3BP PILRA SOS2

2.69e-041976654992_UP
DrugLY 294002; Down 200; 0.1uM; MCF7; HT_HG-U133A

FCHSD2 SATB2 GLI3 PHACTR4 UBXN6

2.69e-041976651641_DN
DrugMeticrane [1084-65-7]; Down 200; 14.6uM; MCF7; HT_HG-U133A

TTLL5 RNF19B PHACTR4 SNAPC4 ZYX

2.69e-041976651671_DN
DrugLevopropoxyphene napsylate [5714-90-9]; Up 200; 7.4uM; PC3; HT_HG-U133A

HIVEP3 AFF2 TTLL5 MMP16 WDR62

2.69e-041976655083_UP
Drug3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; MCF7; HT_HG-U133A

CCDC88C LMF2 AFF2 PDPK1 SOS2

2.69e-041976654764_DN
DrugPiribedil hydrochloride [78213-63-5]; Up 200; 12uM; MCF7; HT_HG-U133A

AFF2 PCLO CCDC57 TESPA1 WDR62

2.69e-041976653512_UP
DrugNimesulide [51803-78-2]; Down 200; 13uM; MCF7; HT_HG-U133A

PNPLA2 TTLL5 UBXN6 WDR62 SOS2

2.69e-041976652275_DN
DrugS(-)-terguride hydrogen maleate [37686-85-4]; Down 200; 8.8uM; MCF7; HT_HG-U133A

LMF2 MICAL3 MMP16 WDR62 SOS2

2.75e-041986656473_DN
DrugUrapidil hydrochloride [64887-14-5]; Down 200; 9.4uM; PC3; HT_HG-U133A

CCDC88C AFF2 SNAPC4 TESPA1 WDR62

2.75e-041986656696_DN
Drugbenserazide hydrochloride; Up 200; 10uM; SKMEL5; HG-U133A

FCHSD2 PDPK1 SNAPC4 DENND2B SOS2

2.75e-04198665631_UP
DrugMetanephrine hydrochloride DL [881-95-8]; Down 200; 17.2uM; MCF7; HT_HG-U133A

PNPLA2 PHF20L1 GLI3 PDPK1 SNAPC4

2.75e-041986655334_DN
Drug0225151-0000 [351320-15-5]; Up 200; 10uM; PC3; HT_HG-U133A

MMP16 CCDC57 WDR62 SERTAD3 SOS2

2.75e-041986656426_UP
Drugcelecoxib; Up 200; 10uM; PC3; HG-U133A

TANC2 HIVEP3 CD2 SATB2 INTS1

2.75e-04198665482_UP
DrugNitrendipine [39562-70-4]; Down 200; 11uM; MCF7; HT_HG-U133A

LMF2 TTLL5 RNF19B DENND2B SOS2

2.75e-041986655405_DN
DrugNaloxone hydrochloride [357-08-4]; Down 200; 11uM; MCF7; HT_HG-U133A

PCLO RNF19B DENND2B WDR62 SOS2

2.75e-041986655243_DN
DrugAtropine-N-oxide hydrochloride [4574-60-1]; Down 200; 11.8uM; PC3; HT_HG-U133A

PCLO TTLL5 RNF19B SNAPC4 ZYX

2.75e-041986652054_DN
DrugIsoniazid [54-85-3]; Up 200; 29.2uM; PC3; HT_HG-U133A

CCDC88C PNPLA2 PCLO TTLL5 SOS2

2.75e-041986652083_UP
DrugEstradiol-17 beta [50-28-2]; Down 200; 14.6uM; HL60; HT_HG-U133A

HIVEP3 PHF20L1 BRPF1 INTS1 SOS2

2.75e-041986651299_DN
DrugMetolazone [17560-51-9]; Up 200; 11uM; HL60; HG-U133A

HIVEP3 PNPLA2 AFF2 BRPF1 SOS2

2.75e-041986652014_UP
DrugHydroquinine hydrobromide hydrate [304695-81-6]; Up 200; 9.4uM; HL60; HG-U133A

HIVEP3 LMF2 GLI3 TTLL5 SNAPC4

2.75e-041986651775_UP
DrugTimolol maleate salt [26921-17-5]; Down 200; 9.2uM; MCF7; HT_HG-U133A

PNPLA2 TTLL5 MMP16 RPH3A SOS2

2.75e-041986655645_DN
DrugDantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A

HIVEP3 CD2 LMF2 ZYX WDR62

2.81e-041996652329_UP
DrugGalanthamine hydrobromide [1953-04-4]; Up 200; 10.8uM; MCF7; HT_HG-U133A

THSD4 HIVEP3 UBXN6 MMP16 WDR62

2.81e-041996652787_UP
DrugGibberellic acid [77-06-5]; Up 200; 11.6uM; PC3; HT_HG-U133A

THSD4 RNF19B GAL3ST4 MMP16 APBB1IP

2.81e-041996654234_UP
DrugVidarabine [5536-17-4]; Down 200; 15uM; MCF7; HT_HG-U133A

LMF2 GLI3 TTLL5 PHACTR4 SNAPC4

2.81e-041996657203_DN
DrugPiroxicam [36322-90-4]; Down 200; 12uM; MCF7; HT_HG-U133A

HIVEP3 LMF2 PLEKHG6 RNF19B SNAPC4

2.81e-041996652252_DN
DrugLevamisole hydrochloride [16595-80-5]; Down 200; 16.6uM; MCF7; HT_HG-U133A

HIVEP3 LMF2 RNF19B MMP16 ZYX

2.81e-041996652257_DN
DrugNicergoline; Down 200; 8.2uM; MCF7; HT_HG-U133A

PNPLA2 TTLL5 RNF19B MMP16 DENND2B

2.81e-041996652220_DN
DrugCytisine (-) [485-35-8]; Up 200; 21uM; MCF7; HT_HG-U133A

TANC2 AFF2 PLEKHG6 TTLL5 SOS2

2.81e-041996656217_UP
DrugFlurbiprofen [5104-49-4]; Up 200; 16.4uM; MCF7; HT_HG-U133A

CLIP3 PHF20L1 IL25 PCLO WDR62

2.88e-042006655634_UP
DrugSulfabenzamide [127-71-9]; Up 200; 14.4uM; MCF7; HT_HG-U133A

HIVEP3 LMF2 PLEKHG6 RNF19B MMP16

2.88e-042006652814_UP
Drugcarbonyl sulfide

DAZ4 DAZ1 DAZ3 DAZ2

3.61e-04116664CID000010039
DrugTXB2 (thromboxane B2

DAZ4 DAZ1 DAZ3 DAZ2

3.86e-04118664CID000005461
DiseaseMale sterility due to Y-chromosome deletions

DAZ4 DAZ1 DAZ3 DAZ2

1.23e-098624C2931163
DiseasePartial chromosome Y deletion

DAZ4 DAZ1 DAZ3 DAZ2

1.23e-098624C1507149
DiseaseSpermatogenic Failure, Nonobstructive, Y-Linked

DAZ1 DAZ3 DAZ2

4.85e-0616623C1839071
DiseaseSPERMATOGENIC FAILURE, Y-LINKED, 2

DAZ1 DAZ3 DAZ2

4.85e-0616623415000
DiseaseSpermatogenic failure, Y-linked, 2

DAZ1 DAZ3 DAZ2

4.85e-0616623cv:C1839071
Diseasetumor necrosis factor-alpha measurement

PHF20L1 PHACTR4 ROBO1

1.52e-0449623EFO_0004684
DiseaseNephrotic Syndrome

CD2 KANK1

1.47e-0327622C0027726
Diseasecortical surface area measurement

THSD4 TANC2 CCDC88C ZNF536 SATB2 GLI3 GAL3ST4 ROBO1 SOS2

1.90e-031345629EFO_0010736

Protein segments in the cluster

PeptideGeneStartEntry
HHSKNERPARPPPPI

CCDC50

256

Q8IVM0
GQPRPPHRPAQACRK

DEPP1

61

Q9NTK1
HKPAPRKEPRPNIPL

AFF2

676

P51816
RPPPPGHRVQHQPQK

CD2

296

P06729
HQQKGPPLPRPRVQP

CD2

321

P06729
RNHRAPPLTPSKPPV

RASGRP1

436

O95267
RPPVPPKRQENPGHP

APBB1IP

626

Q7Z5R6
LLKDRHPPAPSPQNP

DENND2B

66

P78524
ARHVQPRPLVVNPPP

DAZ2

121

Q13117
ARHVQPRPLVVNPPP

DAZ3

121

Q9NR90
PRPPIHQQPPERRVV

MFSD10

11

Q14728
NRPNPLLALPPARPH

PNPLA2

256

Q96AD5
PRPEKPRHPPLAKEN

MICAL3

1551

Q7RTP6
PRHPPLAKENGRLPA

MICAL3

1556

Q7RTP6
KQRGDIHPRPPPPRD

GLI3

641

P10071
RIVPPLQHNSPPPKE

MAJIN

136

Q3KP22
HKQPPPREPARAQAP

GIGYF1

786

O75420
PPRRPPPHILDQVKS

INTS1

841

Q8N201
RPRQAPVPPASHAPA

CCDC88C

1781

Q9P219
LRIQPTKPPNHRPAE

PCLO

4926

Q9Y6V0
ANRNHPALPLSPPLP

PCED1B

281

Q96HM7
PARPASAPQRHPAPV

GXYLT2

36

A0PJZ3
ENRQLPPPSPQLPKH

KANK1

136

Q14678
TDFPKVVNRPRPHPP

LRRC71

76

Q8N4P6
RGNIHPPRDPNPPQL

GAL3ST4

226

Q96RP7
PPPKPAHRNSNPVIA

PHACTR4

261

Q8IZ21
LRDIPLRPHPPDPQA

PLEKHG6

626

Q3KR16
LRPHPPDPQAPQRRS

PLEKHG6

631

Q3KR16
RAPPSHRPLKSPQNE

PILRA

281

Q9UKJ1
ARHVQPRPLVVNPPP

DAZ1

121

Q9NQZ3
ARHVQPRPLVVNPPP

DAZ1

286

Q9NQZ3
ARHVQPRPLVVNPPP

DAZ1

451

Q9NQZ3
QDPPHVPPRVPRAAR

C21orf58

271

P58505
RSPKPPQAPQHPEEH

CCDC57

801

Q2TAC2
LQPEGDPPSRPRKPH

C13orf46

46

A0A1B0GUA9
TVPVPPLEPARPNRH

IL25

56

Q9H293
ARHVQPRPLVVNPPP

DAZ4

121

Q86SG3
ARHVQPRPLVVNPPP

DAZ4

286

Q86SG3
LRPVRAAPPPPTQNH

FCHSD2

711

O94868
AAPPPPTQNHRRPAE

FCHSD2

716

O94868
ERRQKPVVHPSAPAP

CLIP3

36

Q96DZ5
PPQPVNPPRPFKHSE

PHF20L1

396

A8MW92
PRPQRPAETKAHLPP

NUTM2F

346

A1L443
PAETKAHLPPPRPQR

NUTM2F

351

A1L443
AHLPPPRPQRPAETN

NUTM2F

356

A1L443
PRPQRPAETNAHLPP

NUTM2F

361

A1L443
PAETNAHLPPPRPQR

NUTM2F

366

A1L443
AHLPPPRPQRPAETK

NUTM2F

371

A1L443
PRPQRPAETKAHLPP

NUTM2G

346

Q5VZR2
PPVPAEHRAPPQIRR

KATNAL1

101

Q9BW62
APEQPAPEPKHPARA

RPH3A

186

Q9Y2J0
RRARAKPQAEPPPPA

RNF19B

46

Q6ZMZ0
PVPPRQNSSPHLPKL

SOS2

1291

Q07890
SRPPPVVVPHQPRLD

LMF2

491

Q9BU23
QHLVPSPPKHPRPRD

LRRC56

446

Q8IYG6
QHAQPPPQPRKKRPE

PDPK1

66

O15530
NHPPIPRAVKPEPTN

SATB2

341

Q9UPW6
SVNPNEIKPHPPTPR

TANC2

1756

Q9HCD6
KEPARAPPEPPHNLF

SERTAD3

161

Q9UJW9
DHDNPPPPQQTPLRK

BRPF1

46

P55201
QPRHSREVPRPPVPQ

LINC01465

96

Q8N7H1
EQTPLPQKRLPTPHP

SEMA6B

711

Q9H3T3
AHKEKPNQPAPRPPR

UBXN6

31

Q9BZV1
FPQPAPRQPHLASRP

TMIGD2

226

Q96BF3
VPPHRSIPPADPRKN

MMP16

306

P51512
PQPNKRHSPSPRPRA

SRRM1

676

Q8IYB3
PRAHPHQPEDRVPPN

HIVEP3

2391

Q5T1R4
QHQPDRRRQPVSPPP

ROBO1

1286

Q9Y6N7
RPDLKPPPHAQQAPL

ZNF536

221

O15090
LPAHPSNPQLPEARP

WDR62

1351

O43379
EKPRVQEKQHPVPPP

ZYX

321

Q15942
PPRLPQAGARDPPVH

SNAPC4

816

Q5SXM2
PRDRPPPPHNTPKRN

TESPA1

296

A2RU30
PEPERSPPNRKRPAN

C9orf78

256

Q9NZ63
VPPAPQPPRRSRDHN

THSD4

606

Q6ZMP0
HAAPKPPQLRSPRLP

ZNF629

606

Q9UEG4
PTHPRRKPLPPNNVT

ABI3BP

706

Q7Z7G0
VPKPPPNHEQVLRRA

TTLL5

1226

Q6EMB2
RPQSRDPFAPLHKPP

KMT2D

2456

O14686