Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	odorant binding	OR8J2 OR5AC1 OR5AC2 OR5H8 OR5K3 OR5H2 OR5K2	7.24e-08	127	57	7	GO:0005549
GeneOntologyMolecularFunction	olfactory receptor activity	OR8J2 OR5AC1 OR5AC2 OR5H8 OR4Q3 OR5K3 OR5H2 OR5K2	2.89e-05	431	57	8	GO:0004984
GeneOntologyMolecularFunction	glycosphingolipid binding	SELP LAMA1	6.12e-04	13	57	2	GO:0043208
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR8J2 OR5AC1 OR5AC2 OR5H8 OR4Q3 OR5K3 OR5H2 OR5K2 ADGRA2	8.34e-04	884	57	9	GO:0004930
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR8J2 OR5AC1 OR5AC2 OR5H8 SCNN1A OR4Q3 OR5K3 OR5H2 OR5K2	2.03e-05	547	58	9	GO:0007606
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR8J2 OR5AC1 OR5AC2 OR5H8 OR4Q3 OR5K3 OR5H2 OR5K2	2.66e-05	432	58	8	GO:0050911
GeneOntologyBiologicalProcess	sensory perception of smell	OR8J2 OR5AC1 OR5AC2 OR5H8 OR4Q3 OR5K3 OR5H2 OR5K2	4.48e-05	465	58	8	GO:0007608
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR8J2 OR5AC1 OR5AC2 OR5H8 OR4Q3 OR5K3 OR5H2 OR5K2	6.03e-05	485	58	8	GO:0050907
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR8J2 OR5AC1 OR5AC2 OR5H8 OR4Q3 OR5K3 OR5H2 OR5K2	1.03e-04	524	58	8	GO:0009593
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR8J2 OR5AC1 OR5AC2 OR5H8 OR4Q3 OR5K3 OR5H2 OR5K2	2.12e-04	582	58	8	GO:0050906
Domain	SBF2	SBF1 SBF2	2.74e-05	3	57	2	PF12335
Domain	SBF1/SBF2	SBF1 SBF2	2.74e-05	3	57	2	IPR022096
Domain	Myotubularin-like_Pase_dom	SBF1 SBF2	8.13e-04	14	57	2	IPR010569
Domain	uDENN	SBF1 SBF2	8.13e-04	14	57	2	SM00800
Domain	PPASE_MYOTUBULARIN	SBF1 SBF2	8.13e-04	14	57	2	PS51339
Domain	Myotubularin_fam	SBF1 SBF2	8.13e-04	14	57	2	IPR030564
Domain	Myotub-related	SBF1 SBF2	8.13e-04	14	57	2	PF06602
Domain	uDENN	SBF1 SBF2	9.37e-04	15	57	2	PF03456
Domain	UDENN	SBF1 SBF2	1.07e-03	16	57	2	PS50946
Domain	DDENN	SBF1 SBF2	1.07e-03	16	57	2	PS50947
Domain	GRAM	SBF1 SBF2	1.07e-03	16	57	2	SM00568
Domain	DENN	SBF1 SBF2	1.07e-03	16	57	2	SM00799
Domain	dDENN	SBF1 SBF2	1.07e-03	16	57	2	SM00801
Domain	DENN	SBF1 SBF2	1.07e-03	16	57	2	PF02141
Domain	dDENN_dom	SBF1 SBF2	1.07e-03	16	57	2	IPR005112
Domain	uDENN_dom	SBF1 SBF2	1.07e-03	16	57	2	IPR005113
Domain	dDENN	SBF1 SBF2	1.07e-03	16	57	2	PF03455
Domain	DENN	SBF1 SBF2	1.07e-03	16	57	2	PS50211
Domain	DENN_dom	SBF1 SBF2	1.07e-03	16	57	2	IPR001194
Domain	GRAM	SBF1 SBF2	2.03e-03	22	57	2	PF02893
Domain	GRAM	SBF1 SBF2	2.03e-03	22	57	2	IPR004182
Domain	IQ_motif_EF-hand-BS	UBE3C MYO16 IQCF6	2.62e-03	90	57	3	IPR000048
Domain	IQ	UBE3C MYO16 IQCF6	2.88e-03	93	57	3	PS50096
Domain	ARM-type_fold	AP2A2 DOCK11 PDS5A WDFY4 UNC79	3.70e-03	339	57	5	IPR016024
Domain	Olfact_rcpt	OR5AC2 OR4Q3 OR5K3 OR5H2 OR5K2	6.87e-03	393	57	5	IPR000725
Pubmed	Distinct roles for the Charcot-Marie-Tooth disease-causing endosomal regulators Mtmr5 and Mtmr13 in axon radial sorting and Schwann cell myelination.	SBF1 SBF2	3.03e-06	2	61	2	34718573
Pubmed	Modulation of the combinatorial code of odorant receptor response patterns in odorant mixtures.	OR5AC1 OR5H8 OR5H2	1.46e-05	27	61	3	32061665
Pubmed	Glycosylation catalyzed by lysyl hydroxylase 3 is essential for basement membranes.	LAMA1 PLOD1	1.81e-05	4	61	2	16467571
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR5AC1 OR5H8 OR4Q3 OR5K3 OR5H2 OR5K2	2.95e-05	340	61	6	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR5AC1 OR5H8 OR4Q3 OR5K3 OR5H2 OR5K2	2.95e-05	340	61	6	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR5AC1 OR5H8 OR4Q3 OR5K3 OR5H2 OR5K2	3.10e-05	343	61	6	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR5AC1 OR5H8 OR4Q3 OR5K3 OR5H2 OR5K2	3.25e-05	346	61	6	14611657
Pubmed	A protein interaction landscape of breast cancer.	THOC1 SERPINB9 AP2A2 PDS5A UBE3C PLOD1 HNRNPR	1.20e-04	634	61	7	34591612
Pubmed	Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human.	SBF1 SBF2	1.35e-04	10	61	2	9736772
Pubmed	Charcot-Marie-Tooth Neuropathy Type 4 – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	SBF1 SBF2	1.65e-04	11	61	2	20301641
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	AP2A2 SBF2 PDS5A ZFC3H1 WDFY4 KIF1C	2.26e-04	493	61	6	15368895
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	THOC1 GTF2H4 SBF1 DOCK11 ZFC3H1 PLOD1 HNRNPR	2.71e-04	724	61	7	36232890
Pubmed	Engagement of the G3BP2-TRIM25 Interaction by Nucleocapsid Protein Suppresses the Type I Interferon Response in SARS-CoV-2-Infected Cells.	DYRK4 THAP9 HNRNPR	3.29e-04	76	61	3	36560452
Pubmed	Natural selection on the olfactory receptor gene family in humans and chimpanzees.	OR8J2 OR5H8	4.05e-04	17	61	2	12908129
Pubmed	Polymorphisms in innate immunity genes and risk of childhood leukemia.	SELP ICAM2 SCNN1A ALOX15B	4.79e-04	206	61	4	20438785
Pubmed	Risk of meningioma and common variation in genes related to innate immunity.	SELP ICAM2 SCNN1A ALOX15B	4.88e-04	207	61	4	20406964
Pubmed	Common variation in genes related to innate immunity and risk of adult glioma.	SELP ICAM2 SCNN1A ALOX15B	4.97e-04	208	61	4	19423540
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	SBF1 PDS5A UBE3C ZFC3H1	5.34e-04	212	61	4	33853758
Pubmed	The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates.	OR5AC2 OR4Q3	7.48e-04	23	61	2	10706615
Pubmed	Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	DZIP3 PDS5A KIF1C	7.79e-04	102	61	3	9734811
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	GTF2H4 SBF1 DOCK11 ZFC3H1 PLOD1	1.05e-03	440	61	5	34244565
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	AP2A2 DOCK11 PLOD1 GARRE1 KIF1C	1.12e-03	446	61	5	24255178
Pubmed	Identification of cathepsin K as a novel marker of adiposity in white adipose tissue.	ATP8B3 MYO16	1.19e-03	29	61	2	12652657
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	GTF2H4 DTWD2 CTC1 ZFC3H1 EXOC3L2	1.20e-03	453	61	5	29656893
Pubmed	Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.	AP2A2 CTC1 UBE3C ZFC3H1 HNRNPR	1.63e-03	486	61	5	30940648
Pubmed	Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.	UBE3C EXOC3L2	1.64e-03	34	61	2	19197348
Pubmed	Microtubule-associated proteins 1 (MAP1) promote human immunodeficiency virus type I (HIV-1) intracytoplasmic routing to the nucleus.	RLF CPT1C	1.64e-03	34	61	2	25505242
Cytoband	Ensembl 112 genes in cytogenetic band chr3q11	OR5AC1 OR5AC2 OR5H8 OR5K3 OR5H2 OR5K2	1.05e-10	54	61	6	chr3q11
Cytoband	3q12.1	OR5AC2 OR5H8 OR5K3 OR5H2	1.66e-08	21	61	4	3q12.1
Cytoband	3q11.2	OR5AC1 OR5K2	5.53e-04	26	61	2	3q11.2
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	LILRA2 PTPRH CPT1C USP29 EXOC3L2 GARRE1 NLRP13	1.01e-03	1192	61	7	chr19q13
Cytoband	4p14	NWD2 PDS5A	1.44e-03	42	61	2	4p14
GeneFamily	Olfactory receptors, family 5	OR5AC1 OR5AC2 OR5H8 OR5K3 OR5H2 OR5K2	2.88e-07	112	44	6	152
GeneFamily	Myotubularins\|Phosphoinositide phosphatases	SBF1 SBF2	5.96e-04	15	44	2	903
GeneFamily	Guanylate cyclase receptors\|DENN/MADD domain containing	SBF1 SBF2	1.68e-03	25	44	2	504
Coexpression	GSE19374_UNINF_VS_LISTERIA_INFECTED_MACROPHAGE_DN	AP2A2 PTPRH CTC1 UGGT2 PLOD1 GARRE1	5.03e-06	198	58	6	M7265
Disease	Moyamoya disease	SBF2 FSTL4 PLOD1	6.42e-05	40	57	3	MONDO_0016820
Disease	Charcot-Marie-Tooth disease type 4	SBF1 SBF2	2.82e-04	13	57	2	cv:C4082197
Disease	airway responsiveness measurement	DZIP3 WDFY4	9.85e-04	24	57	2	EFO_0006897
Disease	Alzheimer disease, peptic ulcer disease	AP2A2 EXOC3L2	2.59e-03	39	57	2	MONDO_0004247, MONDO_0004975
Disease	Charcot-Marie-Tooth disease	SBF1 SBF2	3.00e-03	42	57	2	cv:C0007959
Disease	interleukin 1 receptor antagonist measurement	LILRA2 UBE3C	4.74e-03	53	57	2	EFO_0004754
Disease	IGFBP-3 measurement	GREB1 UNC79	4.92e-03	54	57	2	EFO_0004626
Disease	adverse effect, response to xenobiotic stimulus	LAMA1 SCNN1A	5.85e-03	59	57	2	EFO_0009658, GO_0009410

Protein segments in the cluster

Peptide	Gene	Start	Entry
LCHRVVANLLFQELQ	EXOC3L2	166	Q2M3D2
LQRFQCGELPFLTHV	CTC1	1176	Q2NKJ3
CTLQLLVFRNGRLFH	ADGRA2	641	Q96PE1
VLGQFCFLQRLLLVH	ATP8B3	971	O60423
NRFCFQVTRLLLAHG	ASB6	236	Q9NWX5
LCSFQLQHGAQIRLS	DTWD2	251	Q8NBA8
LVRACNQLGQFLQHR	AP2A2	326	O94973
FLALSQRHLNIIVGF	NWD2	1621	Q9ULI1
EVRTLQQCLFLHFQA	MSANTD2	481	Q6P1R3
GLVFRLVFCGLNHIN	OR5K2	161	Q8NHB8
RFLLLFRCLHFVNNS	PGBD4	196	Q96DM1
QCFLGRFNDIHVPVR	PDS5A	326	Q29RF7
GILFRLTFCNSNIIH	OR5H8	161	P0DN80
TLLCQSRGQFHTFLL	LILRA2	341	Q8N149
LSFFIQGNRISVCHI	FBXW10B	661	O95170
FPNRGFLHQLCRLDQ	DUSP13	166	Q6B8I1
NLRVHSAGLLLCRFN	GREB1	1746	Q4ZG55
LFQGYRSCLQLIRIH	SBF2	366	Q86WG5
FHQLFREQRPQCFIL	MYO16	481	Q9Y6X6
IILITLRTHFCQGQN	OR4Q3	221	Q8NH05
VLIFRLTFCNSNIIH	OR5H2	166	Q8NGV7
HLGVCISVANNRLFV	HNRNPR	236	O43390
GQFIREQHCLFRSIP	KIF1C	536	O43896
EFLLRLTFCGSHQIN	OR5K3	161	A6NET4
RFLQARQAACIIQSH	IQCF6	61	A8MYZ5
FLQCRRDFGLLHLEQ	DZIP3	866	Q86Y13
INITLDHRCRIFQNL	PLOD1	196	Q02809
FRQLGITNVLSLFCA	SBF1	216	O95248
GLLFRLTFCRSNIIH	OR5AC1	161	P0C628
HVSLLLRLTFCRFNI	OR5AC2	161	Q9NZP5
FFLRHLAIINLCNST	OR8J2	61	Q8NGG1
LQLAHFRDRGQFCLT	CPT1C	571	Q8TCG5
RNHFCITFELLGINL	DYRK4	176	Q9NR20
RQIIFGICFFHAIIQ	DNAH6	3686	Q9C0G6
QCGFSNAVVQILRLH	GLRX5	66	Q86SX6
GVCRALESFFQHRNI	GRID2IP	411	A4D2P6
RFLVNCHDLTFNILG	DOCK11	366	Q5JSL3
LQRVLLLFRAAQCSF	CPLANE1	1191	Q9H799
TNLIINHIRFGFIFN	FSTL4	601	Q6MZW2
VLGRCFLTVVQVHFQ	GARRE1	166	O15063
QRFQRVVFGISQLLC	SELP	11	P16109
FFCNNTTIHGAIRLV	SCNN1A	61	P37088
QFLNGLNPVLIRRCH	ALOX15B	241	O15296
QSRFCIVLQIFLRLF	RNF139	46	Q8WU17
RSFHGCIKNLIFNLE	LAMA1	2641	P25391
SVLLCFIFGQHLRQQ	ICAM2	241	P13598
RVHLQCRNLQEFLGG	GTF2H4	11	Q92759
RQFGVIAKTQQHLFC	RLF	341	Q13129
LFFIRHNRANSILFC	SERPINB9	356	P50453
CHLLRLIRNAFQNFQ	THAP9	416	Q9H5L6
FQNCIGTIHFLRLIN	THAP9	501	Q9H5L6
IGILACQLRGHFSTQ	WDFY4	1531	Q6ZS81
FQLSNNIRSVVLRHC	USP29	51	Q9HBJ7
FCPSLNHIFIQLARN	TXNDC11	721	Q6PKC3
GQTFCQNIHLIQFAR	ZNF10	216	P21506
NTVGVNIFRTHQLFC	UGGT2	846	Q9NYU1
FLHQCILRFLQQSAQ	PTPRH	1071	Q9HD43
LLFRVQLHIFTGRCQ	ZFC3H1	1481	O60293
QLHIFTGRCQSALAI	ZFC3H1	1486	O60293
QNTVFCGRIQLFLAR	THOC1	151	Q96FV9
QIRQHCLAFRQGLAN	UBE3C	931	Q15386
LLFSELVQHCQSRVF	TRAPPC5	31	Q8IUR0
GVAKQFLRCIFHQLA	UNC79	2076	Q9P2D8
FLRCIFHQLAPNGIF	UNC79	2081	Q9P2D8
SIQHVTRLCLGFNRL	NLRP13	836	Q86W25