Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	benzodiazepine receptor binding	RIMBP3 RIMBP3C RIMBP3B	2.67e-06	5	130	3	GO:0030156
GeneOntologyBiologicalProcess	positive regulation of synapse assembly	DLG5 CUX2 LRTM1 AMIGO1 EFNA5 SLITRK5 AGRN	1.19e-06	86	130	7	GO:0051965
GeneOntologyBiologicalProcess	spermatid development	BRIP1 TTLL5 FNDC3A IQCN RIMBP3 FANCG SYCP1 RIMBP3C RIMBP3B CFAP157	6.45e-06	262	130	10	GO:0007286
GeneOntologyBiologicalProcess	spermatid differentiation	BRIP1 TTLL5 FNDC3A IQCN RIMBP3 FANCG SYCP1 RIMBP3C RIMBP3B CFAP157	8.95e-06	272	130	10	GO:0048515
GeneOntologyBiologicalProcess	positive regulation of cell junction assembly	DLG5 CUX2 LRTM1 AMIGO1 EFNA5 SLITRK5 AGRN	2.50e-05	136	130	7	GO:1901890
GeneOntologyBiologicalProcess	regulation of synapse assembly	DLG5 CUX2 LRTM1 IGSF11 AMIGO1 EFNA5 SLITRK5 AGRN	4.31e-05	202	130	8	GO:0051963
GeneOntologyBiologicalProcess	positive regulation of nervous system development	ARHGAP32 DLG5 CUX2 SERPINF1 LRTM1 AMIGO1 RGS14 EFNA5 SLITRK5 LRP2 AGRN	6.96e-05	418	130	11	GO:0051962
GeneOntologyBiologicalProcess	axon guidance	LRTM1 APBB2 LAMC3 EFNA5 NFIB NGFR LRP2 ULK2 AGRN	8.29e-05	285	130	9	GO:0007411
GeneOntologyBiologicalProcess	neuron projection guidance	LRTM1 APBB2 LAMC3 EFNA5 NFIB NGFR LRP2 ULK2 AGRN	8.51e-05	286	130	9	GO:0097485
GeneOntologyBiologicalProcess	neuron projection morphogenesis	ARHGAP32 CUX2 LRTM1 APBB2 LAMC3 AMIGO1 EFNA5 NFIB SLITRK5 NGFR LRP2 NYAP1 ULK2 AGRN RASAL1	1.63e-04	802	130	15	GO:0048812
GeneOntologyBiologicalProcess	regulation of nervous system development	ARHGAP32 DLG5 CUX2 SERPINF1 LRTM1 AMIGO1 RGS14 EFNA5 SLITRK5 NGFR LRP2 ULK2 AGRN	1.63e-04	625	130	13	GO:0051960
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	ARHGAP32 CUX2 LRTM1 APBB2 LAMC3 AMIGO1 EFNA5 NFIB SLITRK5 NGFR LRP2 NYAP1 ULK2 AGRN RASAL1	2.05e-04	819	130	15	GO:0120039
GeneOntologyBiologicalProcess	cell projection morphogenesis	ARHGAP32 CUX2 LRTM1 APBB2 LAMC3 AMIGO1 EFNA5 NFIB SLITRK5 NGFR LRP2 NYAP1 ULK2 AGRN RASAL1	2.24e-04	826	130	15	GO:0048858
GeneOntologyBiologicalProcess	germ cell development	BRIP1 ARID4B TTLL5 FNDC3A IQCN RIMBP3 FANCG SYCP1 RIMBP3C RIMBP3B CFAP157	2.42e-04	482	130	11	GO:0007281
GeneOntologyBiologicalProcess	axonogenesis	ARHGAP32 LRTM1 APBB2 LAMC3 AMIGO1 EFNA5 NFIB SLITRK5 NGFR LRP2 ULK2 AGRN	2.47e-04	566	130	12	GO:0007409
GeneOntologyBiologicalProcess	spermatogenesis	BRIP1 ARID4B GALNT3 TDRD9 TTLL5 FNDC3A IQCN RIMBP3 USP26 FANCG SYCP1 RIMBP3C RIMBP3B CFAP157	2.56e-04	744	130	14	GO:0007283
GeneOntologyBiologicalProcess	developmental process involved in reproduction	BRIP1 ARID4B GALNT3 TDRD9 TTLL5 SERPINF1 FNDC3A IQCN CBL RIMBP3 USP26 FANCG SYCP1 LRP2 RIMBP3C MYOCD RIMBP3B PLK4 CFAP157	2.70e-04	1235	130	19	GO:0003006
GeneOntologyBiologicalProcess	male gamete generation	BRIP1 ARID4B GALNT3 TDRD9 TTLL5 FNDC3A IQCN RIMBP3 USP26 FANCG SYCP1 RIMBP3C RIMBP3B CFAP157	3.26e-04	762	130	14	GO:0048232
GeneOntologyCellularComponent	basement membrane	COL4A6 LAMB4 SERPINF1 LAMC3 FBN1 EFNA5 HMCN1 CST3 MMRN2 AGRN	4.66e-09	122	130	10	GO:0005604
GeneOntologyCellularComponent	microtubule organizing center	CCDC14 CEP104 DLG5 IFT172 TTLL5 WRN CCDC187 CDC14A SPAG5 RGS14 POC5 MPHOSPH9 TACC3 PLK4 IL4R CFAP157	1.90e-04	919	130	16	GO:0005815
MousePheno	ectopic manchette	IQCN RIMBP3 RIMBP3C RIMBP3B	1.28e-05	19	110	4	MP:0009377
Domain	2-Hacid_dh_C	CTBP1 CTBP2	2.81e-04	4	129	2	PF02826
Domain	2-Hacid_dh	CTBP1 CTBP2	2.81e-04	4	129	2	PF00389
Domain	D_2_HYDROXYACID_DH_1	CTBP1 CTBP2	2.81e-04	4	129	2	PS00065
Domain	D_2_HYDROXYACID_DH_2	CTBP1 CTBP2	2.81e-04	4	129	2	PS00670
Domain	D_2_HYDROXYACID_DH_3	CTBP1 CTBP2	2.81e-04	4	129	2	PS00671
Domain	D-isomer_2_OHA_DH_cat_dom	CTBP1 CTBP2	2.81e-04	4	129	2	IPR006139
Domain	D-isomer_DH_CS	CTBP1 CTBP2	2.81e-04	4	129	2	IPR029753
Domain	EGF_1	LAMB4 LAMC3 ITGB7 FBN1 HMCN1 LRP2 LTBP2 AGRN	3.98e-04	255	129	8	PS00022
Domain	EGF-like_CS	LAMB4 LAMC3 ITGB7 FBN1 HMCN1 LRP2 LTBP2 AGRN	4.65e-04	261	129	8	IPR013032
Domain	D-isomer_DH_NAD-bd	CTBP1 CTBP2	4.67e-04	5	129	2	IPR006140
Domain	EGF_2	LAMB4 LAMC3 ITGB7 FBN1 HMCN1 LRP2 LTBP2 AGRN	5.14e-04	265	129	8	PS01186
Domain	cEGF	FBN1 HMCN1 LRP2	7.45e-04	26	129	3	PF12662
Domain	cEGF	FBN1 HMCN1 LRP2	7.45e-04	26	129	3	IPR026823
Domain	Growth_fac_rcpt_	LAMC3 RSPO3 FBN1 HMCN1 LRP2 LTBP2	7.54e-04	156	129	6	IPR009030
Domain	SH3	ARHGAP32 DLG5 OBSCN RIMBP3 RIMBP3C RIMBP3B FYB2	7.62e-04	216	129	7	SM00326
Pubmed	New loci associated with kidney function and chronic kidney disease.	SHROOM3 ATXN7L2 IFT172 AMIGO1 SLC6A12 RGS14 CST3	6.94e-09	66	134	7	20383146
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	CCDC14 ARHGAP32 DLG5 SHROOM3 CENPE TTLL5 SPAG5 RIMBP3 IARS2 UBR5 LRP2 POC5 MPHOSPH9 CGNL1 GOLGA5 AGRN	2.05e-07	853	134	16	28718761
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3 RIMBP3C RIMBP3B	2.23e-07	4	134	3	19091768
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	ARHGAP32 SHROOM3 NUP98 C15orf39 NFIB SLITRK5 CTBP1 RAI1	5.27e-07	180	134	8	35198878
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	RIMBP3 RIMBP3C RIMBP3B	5.56e-07	5	134	3	17855024
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	CCDC14 ARHGAP32 ATXN7L2 TEP1 SPAG5 AFAP1L2 CST3 LRP2 CTBP1 CTBP2 CHD6 AGRN PRRC2A	7.19e-07	608	134	13	16713569
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	SHROOM3 WRN NUP98 APBB2 IARS2 UBR5 SLITRK5 CTBP1 MPHOSPH9 CGNL1 TACC3 GOLGA5 PCDH9 AGAP3	1.98e-06	777	134	14	35844135
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PRUNE2 ARHGAP32 ZBTB26 AMIGO1 PPP1R26 RGL1 KRBA1 AHRR SLITRK5 CGNL1 PLCH1	3.57e-06	493	134	11	15368895
Pubmed	The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals.	CUX2 RSPO3 EFNA5 NFIB NGFR	4.63e-06	63	134	5	22923088
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ARHGAP32 SHROOM3 ARHGAP24 CENPE UBR5 NISCH CTBP1 CTBP2 ADGRA1 TACC3 UNC79 AGRN PRRC2A RASAL1 RAI1	4.94e-06	963	134	15	28671696
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	C15orf39 SPAG5 ZNF608 UBR5 LRP2 CTBP1 CTBP2 CHD6 TACC3 GOLGA5	5.48e-06	418	134	10	34709266
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SHROOM3 NSD2 OBSCN C15orf39 LAMC3 TEP1 PPP1R26 NISCH SLC35A2 ULK2 AGRN IL4R RASAL1 RAI1 AGAP3 HR	5.89e-06	1105	134	16	35748872
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	CCDC14 DLG5 ARID4B NSD2 TTLL5 SPAG5 ZNF608 CTBP1 CTBP2 CHD6 MPHOSPH9 RAI1	8.06e-06	645	134	12	25281560
Pubmed	POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.	SHROOM3 BRIP1 ARID4B CENPE SPAG5 INSYN2B CHD6 ULK2	1.28e-05	277	134	8	30745168
Pubmed	C-Terminal Binding Protein is Involved in Promoting to the Carcinogenesis of Human Glioma.	CTBP1 CTBP2	1.47e-05	2	134	2	27699603
Pubmed	Molecular cloning and characterization of a cellular phosphoprotein that interacts with a conserved C-terminal domain of adenovirus E1A involved in negative modulation of oncogenic transformation.	CTBP1 CTBP2	1.47e-05	2	134	2	7479821
Pubmed	Highly accurate two-gene classifier for differentiating gastrointestinal stromal tumors and leiomyosarcomas.	PRUNE2 OBSCN	1.47e-05	2	134	2	17360660
Pubmed	Differential Associations of SLCO Transporters with Prostate Cancer Aggressiveness between African Americans and European Americans.	SLCO5A1 SLCO2A1	1.47e-05	2	134	2	33619025
Pubmed	Assembly of human C-terminal binding protein (CtBP) into tetramers.	CTBP1 CTBP2	1.47e-05	2	134	2	29700119
Pubmed	NAD(H) phosphates mediate tetramer assembly of human C-terminal binding protein (CtBP).	CTBP1 CTBP2	1.47e-05	2	134	2	33524397
Pubmed	Expression of CtBP family protein isoforms in breast cancer and their role in chemoresistance.	CTBP1 CTBP2	1.47e-05	2	134	2	20964627
Pubmed	NADH/NAD+ binding and linked tetrameric assembly of the oncogenic transcription factors CtBP1 and CtBP2.	CTBP1 CTBP2	1.47e-05	2	134	2	34997967
Pubmed	Confocal microscopy demonstrates association of LTBP-2 in fibrillin-1 microfibrils and colocalisation with perlecan in the disc cell pericellular matrix.	FBN1 LTBP2	1.47e-05	2	134	2	24867584
Pubmed	Modulation of myocardin function by the ubiquitin E3 ligase UBR5.	UBR5 MYOCD	1.47e-05	2	134	2	20167605
Pubmed	Molecular cloning and functional characterization of brefeldin A-ADP-ribosylated substrate. A novel protein involved in the maintenance of the Golgi structure.	CTBP1 CTBP2	1.47e-05	2	134	2	10364211
Pubmed	CTBP1 and CTBP2 mutations underpinning neurological disorders: a systematic review.	CTBP1 CTBP2	1.47e-05	2	134	2	36331689
Pubmed	Differential spatial expression and subcellular localization of CtBP family members in rodent brain.	CTBP1 CTBP2	1.47e-05	2	134	2	22745816
Pubmed	Cryo-EM structure of CtBP2 confirms tetrameric architecture.	CTBP1 CTBP2	1.47e-05	2	134	2	33264605
Pubmed	Polymorphisms in Complement Factor H and Hemicentin-1 genes in a Japanese population with dry-type age-related macular degeneration.	CFH HMCN1	1.47e-05	2	134	2	17157600
Pubmed	Complement factor H and hemicentin-1 in age-related macular degeneration and renal phenotypes.	CFH HMCN1	1.47e-05	2	134	2	17591627
Pubmed	T Cell Recruitment to the Intestinal Stem Cell Compartment Drives Immune-Mediated Intestinal Damage after Allogeneic Transplantation.	OLFM4 ITGB7	1.47e-05	2	134	2	31278057
Pubmed	Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design.	CTBP1 CTBP2	1.47e-05	2	134	2	24657618
Pubmed	CtBPs promote cell survival through the maintenance of mitotic fidelity.	CTBP1 CTBP2	1.47e-05	2	134	2	19506021
Pubmed	A novel C-terminal binding protein (CTBP2) is closely related to CTBP1, an adenovirus E1A-binding protein, and maps to human chromosome 21q21.3.	CTBP1 CTBP2	1.47e-05	2	134	2	9479502
Pubmed	CtBP, an unconventional transcriptional corepressor in development and oncogenesis.	CTBP1 CTBP2	1.47e-05	2	134	2	11864595
Pubmed	c-Cbl binds to tyrosine-phosphorylated neurotrophin receptor p75 and induces its ubiquitination.	CBL NGFR	1.47e-05	2	134	2	15337528
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PRUNE2 SHROOM3 NSD2 OBSCN APBB2 IQCN TEP1 PLBD2 INKA2 EFNA5 ZNF608 NFIB ZNF589 CTBP1 CTBP2 CHD6 RAI1 AGAP3	1.74e-05	1489	134	18	28611215
Pubmed	Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.	RIMBP3 RIMBP3C RIMBP3B	1.97e-05	14	134	3	17662146
Pubmed	Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.	CCDC14 CEP104 TTLL5 CDC14A POC5 PLK4	2.28e-05	146	134	6	21399614
Pubmed	Evi-1 transforming and repressor activities are mediated by CtBP co-repressor proteins.	CTBP1 CTBP2	4.41e-05	3	134	2	11328817
Pubmed	Loss of heterozygosity in FANCG, FANCF and BRIP1 from head and neck squamous cell carcinoma of the oral cavity.	BRIP1 FANCG	4.41e-05	3	134	2	28440438
Pubmed	Characterization of four autonomous repression domains in the corepressor receptor interacting protein 140.	CTBP1 CTBP2	4.41e-05	3	134	2	14736873
Pubmed	Accumulation of advanced glycation end products promotes atrophic nonunion incidence in mice through a CtBP1/2-dependent mechanism.	CTBP1 CTBP2	4.41e-05	3	134	2	37696386
Pubmed	C-Terminal binding protein is a transcriptional repressor that interacts with a specific class of vertebrate Polycomb proteins.	CTBP1 CTBP2	4.41e-05	3	134	2	9858600
Pubmed	Mechanical strain in actin networks regulates FilGAP and integrin binding to filamin A.	ARHGAP24 ITGB7	4.41e-05	3	134	2	21926999
Pubmed	CtBP promotes metastasis of breast cancer through repressing cholesterol and activating TGF-β signaling.	CTBP1 CTBP2	4.41e-05	3	134	2	30442980
Pubmed	mTOR inhibition rescues osteopenia in mice with systemic sclerosis.	FBN1 IL4R	4.41e-05	3	134	2	25534817
Pubmed	Pinin interacts with C-terminal binding proteins for RNA alternative splicing and epithelial cell identity of human ovarian cancer cells.	CTBP1 CTBP2	4.41e-05	3	134	2	26871283
Pubmed	MCRIP1, an ERK substrate, mediates ERK-induced gene silencing during epithelial-mesenchymal transition by regulating the co-repressor CtBP.	CTBP1 CTBP2	4.41e-05	3	134	2	25728771
Pubmed	Calsenilin interacts with transcriptional co-repressor C-terminal binding protein(s).	CTBP1 CTBP2	4.41e-05	3	134	2	16787403
Pubmed	A L225A substitution in the human tumour suppressor HIC1 abolishes its interaction with the corepressor CtBP.	CTBP1 CTBP2	4.41e-05	3	134	2	16762039
Pubmed	APC mutations in colorectal tumours from FAP patients are selected for CtBP-mediated oligomerization of truncated APC.	CTBP1 CTBP2	4.41e-05	3	134	2	21665989
Pubmed	Analysis of variants in the complement factor H, the elongation of very long chain fatty acids-like 4 and the hemicentin 1 genes of age-related macular degeneration in the Finnish population.	CFH HMCN1	4.41e-05	3	134	2	16885922
Pubmed	LTBP-2 specifically interacts with the amino-terminal region of fibrillin-1 and competes with LTBP-1 for binding to this microfibrillar protein.	FBN1 LTBP2	4.41e-05	3	134	2	17293099
Pubmed	HMG box transcription factor TCF-4's interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cells.	CTBP1 CTBP2	4.41e-05	3	134	2	12711682
Pubmed	Family-based genome scan for age at onset of late-onset Alzheimer's disease in whole exome sequencing data.	WRN LAMC3	4.41e-05	3	134	2	26394601
Pubmed	Phosphorylation of CtBP1 by cAMP-dependent protein kinase modulates induction of CYP17 by stimulating partnering of CtBP1 and 2.	CTBP1 CTBP2	4.41e-05	3	134	2	18184656
Pubmed	ZEB represses transcription through interaction with the corepressor CtBP.	CTBP1 CTBP2	4.41e-05	3	134	2	10359772
Pubmed	Proximity interactions among centrosome components identify regulators of centriole duplication.	CCDC14 SPAG5 POC5 MPHOSPH9 PLK4	4.64e-05	101	134	5	24613305
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	COL4A6 FBN1 HMCN1 MMRN2 LTBP2 AGRN	4.84e-05	167	134	6	22159717
Pubmed	Centrosome-related genes, genetic variation, and risk of breast cancer.	WRN CDC14A SPAG5 TACC3 PLK4	4.86e-05	102	134	5	20508983
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	CFH SERPINF1 FBN1 CST3 PAPPA LTBP2 AGRN	5.24e-05	248	134	7	24006456
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	COL4A6 FBN1 HMCN1 CST3 LTBP2 AGRN	6.28e-05	175	134	6	28071719
Pubmed	Interaction network of human early embryonic transcription factors.	ARID4B NUP98 C15orf39 ZNF608 NFIB CTBP1 CTBP2 RAI1	6.87e-05	351	134	8	38297188
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	CCDC14 DLG5 TTLL5 KRBA1 FBN1 UBR5	8.28e-05	184	134	6	32908313
Pubmed	Comparative immunolocalization of the elastin fiber-associated proteins fibrillin-1, LTBP-2, and MAGP-1 with components of the collagenous and proteoglycan matrix of the fetal human intervertebral disc.	FBN1 LTBP2	8.80e-05	4	134	2	21540769
Pubmed	Hdm2 recruits a hypoxia-sensitive corepressor to negatively regulate p53-dependent transcription.	CTBP1 CTBP2	8.80e-05	4	134	2	12867035
Pubmed	Calpain-mediated cleavage generates a ZBTB18 N-terminal product that regulates HIF1A signaling and glioblastoma metabolism.	CTBP1 CTBP2	8.80e-05	4	134	2	35800763
Pubmed	Targeted disruption of the basic Krüppel-like factor gene (Klf3) reveals a role in adipogenesis.	CTBP1 CTBP2	8.80e-05	4	134	2	18391014
Pubmed	Nuclear speckle-associated protein Pnn/DRS binds to the transcriptional corepressor CtBP and relieves CtBP-mediated repression of the E-cadherin gene.	CTBP1 CTBP2	8.80e-05	4	134	2	15542832
Pubmed	Mouse D1Pas1, a DEAD-box RNA helicase, is required for the completion of first meiotic prophase in male germ cells.	TDRD9 SYCP1	8.80e-05	4	134	2	27473657
Pubmed	CENPE, PRC1, TTK, and PLK4 May Play Crucial Roles in the Osteosarcoma Progression.	CENPE PLK4	8.80e-05	4	134	2	33176597
Pubmed	C/EBPalpha and the corepressors CtBP1 and CtBP2 regulate repression of select visceral white adipose genes during induction of the brown phenotype in white adipocytes by peroxisome proliferator-activated receptor gamma agonists.	CTBP1 CTBP2	8.80e-05	4	134	2	19564408
Pubmed	Phenotype and genotype characteristics of age-related macular degeneration in a Japanese population.	CFH SERPINF1	8.80e-05	4	134	2	20132989
Pubmed	Identification of CtBP1 and CtBP2 as corepressors of zinc finger-homeodomain factor deltaEF1.	CTBP1 CTBP2	8.80e-05	4	134	2	10567582
Pubmed	The Ikaros family protein Eos associates with C-terminal-binding protein corepressors.	CTBP1 CTBP2	8.80e-05	4	134	2	12444977
Pubmed	Lack of skin fibrosis in tight skin (TSK) mice with targeted mutation in the interleukin-4R alpha and transforming growth factor-beta genes.	FBN1 IL4R	8.80e-05	4	134	2	11168809
Pubmed	Complement factor H and high-temperature requirement A-1 genotypes and treatment response of age-related macular degeneration.	CFH SERPINF1	8.80e-05	4	134	2	20678803
Pubmed	Weill-Marchesani Syndrome	FBN1 LTBP2	8.80e-05	4	134	2	20301293
Pubmed	HIC1 interacts with a specific subunit of SWI/SNF complexes, ARID1A/BAF250A.	CTBP1 CTBP2	8.80e-05	4	134	2	19486893
Pubmed	A human MAP kinase interactome.	CCDC14 ARHGAP32 ARID4B NUP98 CBL RGL1 CHD6 MPHOSPH9 CGNL1	1.18e-04	486	134	9	20936779
Pubmed	ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes.	UBR5 CTBP1 CTBP2	1.36e-04	26	134	3	25228645
Pubmed	Bhlhb5 regulates the postmitotic acquisition of area identities in layers II-V of the developing neocortex.	CUX2 EFNA5 NGFR	1.36e-04	26	134	3	18957218
Pubmed	Kv2 channel-AMIGO β-subunit assembly modulates both channel function and cell adhesion molecule surface trafficking.	KCNB2 AMIGO1	1.46e-04	5	134	2	34137443
Pubmed	Glucocorticoid-induced tumor necrosis factor receptor-related protein co-stimulation facilitates tumor regression by inducing IL-9-producing helper T cells.	TNFRSF18 IL4R	1.46e-04	5	134	2	26280119
Pubmed	hFOG-2, a novel zinc finger protein, binds the co-repressor mCtBP2 and modulates GATA-mediated activation.	CTBP1 CTBP2	1.46e-04	5	134	2	10438528
Pubmed	Nuclear localization and cell cycle-specific expression of CtIP, a protein that associates with the BRCA1 tumor suppressor.	CTBP1 CTBP2	1.46e-04	5	134	2	10764811
Pubmed	Zinc finger protein Wiz links G9a/GLP histone methyltransferases to the co-repressor molecule CtBP.	CTBP1 CTBP2	1.46e-04	5	134	2	16702210
Pubmed	Leukemic transformation in mice expressing a NUP98-HOXD13 transgene is accompanied by spontaneous mutations in Nras, Kras, and Cbl.	NUP98 CBL	1.46e-04	5	134	2	18566322
Pubmed	HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies.	CTBP1 CTBP2	1.46e-04	5	134	2	16724116
Pubmed	Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex.	CTBP1 CTBP2	1.46e-04	5	134	2	18483224
Pubmed	Auditory hair cell defects as potential cause for sensorineural deafness in Wolf-Hirschhorn syndrome.	NSD2 NGFR	1.46e-04	5	134	2	26092122
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	SHROOM3 FBN1 LRP2 ZNF292	1.68e-04	71	134	4	33541421
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	COL4A6 SERPINF1 FBN1 MMRN2 AGRN	1.83e-04	135	134	5	28675934
Pubmed	Recapitulating early development of mouse musculoskeletal precursors of the paraxial mesoderm in vitro.	SHROOM3 ISM1 MYOCD	2.10e-04	30	134	3	29555813
Pubmed	PLDLS-dependent interaction of E1A with CtBP: regulation of CtBP nuclear localization and transcriptional functions.	CTBP1 CTBP2	2.19e-04	6	134	2	17546044
Pubmed	Overlapping and unique roles for C-terminal binding protein 1 (CtBP1) and CtBP2 during mouse development.	CTBP1 CTBP2	2.19e-04	6	134	2	12101226
Pubmed	A pathogenic CtBP1 missense mutation causes altered cofactor binding and transcriptional activity.	CTBP1 CTBP2	2.19e-04	6	134	2	31041561
Pubmed	Wolf-Hirschhorn Syndrome – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	NSD2 CTBP1	2.19e-04	6	134	2	20301362
Pubmed	FancJ (Brip1) loss-of-function allele results in spermatogonial cell depletion during embryogenesis and altered processing of crossover sites during meiotic prophase I in mice.	BRIP1 SYCP1	2.19e-04	6	134	2	26490168
Interaction	SASS6 interactions	CCDC14 DLG5 CENPE SPAG5 NFIB MPHOSPH9 CGNL1 PLK4	8.55e-06	159	129	8	int:SASS6
Cytoband	2q24-q31	GALNT3 LRP2	2.53e-05	3	134	2	2q24-q31
Coexpression	NABA_BASEMENT_MEMBRANES	COL4A6 LAMB4 LAMC3 HMCN1 AGRN	1.85e-06	40	134	5	M5887
Coexpression	GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_CD4_TCELL_UP	CENPE NSD2 FANCG UBR5 MPHOSPH9 TACC3 PCDH9 PLK4	7.33e-06	194	134	8	M7467
Coexpression	NABA_ECM_GLYCOPROTEINS	LAMB4 LAMC3 RSPO3 FBN1 HMCN1 MMRN2 LTBP2 AGRN	7.90e-06	196	134	8	M3008
Coexpression	NABA_CORE_MATRISOME	COL4A6 LAMB4 LAMC3 RSPO3 FBN1 HMCN1 MMRN2 LTBP2 AGRN	1.26e-05	275	134	9	M5884
Coexpression	NABA_MATRISOME_PRIMARY_METASTATIC_COLORECTAL_TUMOR	SERPINF1 HMCN1 MMRN2 LTBP2 AGRN	1.30e-05	59	134	5	M47989
Coexpression	GSE13547_2H_VS_12_H_ANTI_IGM_STIM_ZFX_KO_BCELL_DN	BRIP1 GALNT3 CENPE NSD2 SPAG5 TACC3 PLK4	3.26e-05	174	134	7	M2996
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3	SHROOM3 ZBTB7C GALNT3 LAMC3 CDC14A SLCO5A1 RSPO3 AFAP1L2 EFNA5 HMCN1 NFIB SLCO2A1 LRP2 PAPPA MYOCD CGNL1 IL4R	3.53e-05	1074	134	17	M1941
Coexpression	BLANCO_MELO_BRONCHIAL_EPITHELIAL_CELLS_INFLUENZA_A_DEL_NS1_INFECTION_DN	CENPE NSD2 SPAG5 FANCG ZNF608 TACC3 PLK4	5.15e-05	187	134	7	M34027
Coexpression	BENPORATH_ES_WITH_H3K27ME3	TBXAS1 PRUNE2 COL4A6 CNNM2 RIMBP3 SLCO5A1 RSPO3 FBN1 SLCO2A1 NGFR LRP2 PAPPA RIMBP3C DLX4 LTBP2 RIMBP3B HR	5.62e-05	1115	134	17	M10371
Coexpression	NABA_MATRISOME_HIGHLY_METASTATIC_BREAST_CANCER	COL4A6 SERPINF1 CST3 AGRN	5.71e-05	41	134	4	M47988
Coexpression	NABA_ECM_GLYCOPROTEINS	LAMC3 RSPO3 FBN1 HMCN1 MMRN2 LTBP2 AGRN	5.88e-05	191	134	7	MM17059
Coexpression	GSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP	CEP104 WRN ZNF608 TOP1MT GOLGA5 ULK2 RAI1	7.61e-05	199	134	7	M7984
Coexpression	NABA_CORE_MATRISOME	COL4A6 LAMC3 RSPO3 FBN1 HMCN1 MMRN2 LTBP2 AGRN	7.78e-05	270	134	8	MM17057
Coexpression	GSE24634_TREG_VS_TCONV_POST_DAY7_IL4_CONVERSION_UP	CENPE NSD2 SPRR3 CDC14A SPAG5 FANCG PLK4	7.86e-05	200	134	7	M4604
Coexpression	GSE30083_SP2_VS_SP4_THYMOCYTE_UP	LAMC3 AMIGO1 CLCNKA ZNF608 LRP2 ADGRA1 GOT1	7.86e-05	200	134	7	M5034
Coexpression	GSE3039_NKT_CELL_VS_B2_BCELL_UP	CFH TBXAS1 GALNT3 CBL CTBP1 CHD6 HR	7.86e-05	200	134	7	M6435
Coexpression	HALLMARK_G2M_CHECKPOINT	CENPE NSD2 WRN NUP98 EFNA5 TACC3 PLK4	7.86e-05	200	134	7	M5901
Coexpression	ZENG_GU_ICB_CONTROL_METAGENE_3_PRECICTIVE_ICB_RESPONSE	APBB2 TEP1 CBL SPAG5 AHRR TEX26 FYB2	1.10e-04	211	134	7	MM17081
Coexpression	GSE9946_IMMATURE_VS_PROSTAGLANDINE2_TREATED_MATURE_DC_UP	ATXN7L2 ISM1 PLBD2 AMIGO1 ZBTB49 KRBA1	1.30e-04	151	134	6	M421
Coexpression	LINDGREN_BLADDER_CANCER_CLUSTER_1_DN	CENPE NSD2 SH2D2A ITGB7 RGL1 PAPPA MPHOSPH9 TACC3 PLK4	1.47e-04	378	134	9	M17788
Coexpression	FLORIO_NEOCORTEX_BASAL_RADIAL_GLIA_UP	LAMB4 CUX2 ARHGAP24 ITGB7 RNASEL ZNF608 MYOCD CGNL1 FYB2	1.65e-04	384	134	9	M798
ToppCell	Adult-Epithelial-basal_cell\|Adult / Lineage, Cell type, age group and donor	CFH COL4A6 CUX2 ZBTB7C SERPINF1 EFNA5 HMCN1 NGFR NYAP1 HR	2.28e-10	183	134	10	00a6b19ca49e3b8e0d1cd387a3515b0ff4b81c81
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 ZBTB7C SERPINF1 KCNB2 SLCO5A1 FBN1 AFAP1L2 MMRN2 PCDH9	5.69e-09	187	134	9	e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-stromal_related\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRUNE2 SERPINF1 LRTM1 RSPO3 FBN1 HMCN1 NGFR PAPPA LTBP2	8.20e-09	195	134	9	1be9502577267ca2a04656a99d57e3e2f124d92e
ToppCell	Adult-Epithelial-basal_cell-D122\|Adult / Lineage, Cell type, age group and donor	CFH COL4A6 CUX2 HMCN1 TEX26 NGFR MMRN2 NYAP1	2.27e-08	154	134	8	38d346402417960044ae999e61f0092b46f2b591
ToppCell	Adult-Mesenchymal-myofibroblast_cell\|Adult / Lineage, Cell type, age group and donor	CFH KCNB2 FANCG FBN1 AFAP1L2 HMCN1 PAPPA LTBP2	4.26e-08	167	134	8	d584a8548a5317bd9686b3be8246ae6ed568796b
ToppCell	367C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)\|367C / Donor, Lineage, Cell class and subclass (all cells)	CFH SERPINF1 LAMC3 RSPO3 FBN1 CST3 SLITRK5 LTBP2	4.68e-08	169	134	8	47fd4adfe54777e69a0fabf8bd34f26223f63275
ToppCell	367C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	CFH SERPINF1 LAMC3 RSPO3 FBN1 CST3 SLITRK5 LTBP2	4.68e-08	169	134	8	e09259d62cd3e42f0919f231ed1164db59b0b6c3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LAMB4 LRTM1 IQCN EFNA5 HMCN1 ULK2 PCDH9 RAI1	8.29e-08	182	134	8	a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMB4 CNNM2 ARHGAP24 EFNA5 HMCN1 CLCNKA CGNL1 PCDH9	1.11e-07	189	134	8	f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCell	COVID-19-Fibroblasts-Other_FB\|COVID-19 / group, cell type (main and fine annotations)	CFH ISM1 APBB2 KCNB2 FBN1 HMCN1 PAPPA LTBP2	1.30e-07	193	134	8	e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	BRIP1 ISM1 SPAG5 SLCO2A1 MYOCD LTBP2 TACC3 PLK4	1.30e-07	193	134	8	bbdfda6665941cfa1965418bb91ef9ff43b1326f
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-stromal_related-FDC\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRUNE2 SERPINF1 LRTM1 RSPO3 HMCN1 NGFR PAPPA LTBP2	1.35e-07	194	134	8	f9fbb043411546d8c9e0321a64165d411f44aeb7
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CFH SH2D3C LAMC3 AFAP1L2 HMCN1 SLCO2A1 MMRN2 AGRN	1.65e-07	199	134	8	1295f34a350bf48987e2fad411aaac3630efd3f1
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CFH PRUNE2 COL4A6 KCNB2 PAPPA MYOCD LTBP2	4.19e-07	153	134	7	1524557514668f515ac1bbe847611f564b265b42
ToppCell	Basal_cells-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	COL4A6 CUX2 SERPINF1 ISM1 EFNA5 NGFR HR	7.87e-07	168	134	7	48089fa2d4a0f31a72405717119b767a92571f01
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	CFH SERPINF1 ISM1 FBN1 HMCN1 PAPPA LTBP2	1.07e-06	176	134	7	510f9a14dc1c151d24d079e0cc004cdf4f86336c
ToppCell	nucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFH COL4A6 SERPINF1 EFNA5 NFIB SLITRK5 NGFR	1.12e-06	177	134	7	cbad1a23851151dbef01ea2af960e6f0944f838b
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CFH PRUNE2 COL4A6 ISM1 KCNB2 MYOCD LTBP2	1.12e-06	177	134	7	b59967219f7d874805768e247c0eb2bc4d4420c8
ToppCell	nucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFH COL4A6 SERPINF1 EFNA5 NFIB SLITRK5 NGFR	1.12e-06	177	134	7	ce86dfaeb74d995a19aea62f0fb15c4c0bb854b0
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH PRUNE2 COL4A6 FBN1 HMCN1 MYOCD LTBP2	1.30e-06	181	134	7	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZBTB7C SERPINF1 APBB2 FBN1 AFAP1L2 MMRN2 CGNL1	1.39e-06	183	134	7	351d575339038bd4a66f408da518c567444208e8
ToppCell	5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SERPINF1 RSPO3 FBN1 NFIB NGFR PAPPA CGNL1	1.45e-06	184	134	7	4d4d8f3f44c67d74c57e7af7b7c158f0157b2f49
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CFH COL4A6 SERPINF1 ISM1 FBN1 PAPPA LTBP2	1.50e-06	185	134	7	7dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TBXAS1 COL4A6 ISM1 FBN1 NFIB NGFR LTBP2	1.50e-06	185	134	7	9f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCell	(0)_MSCs\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	CFH SHROOM3 ISM1 RSPO3 FBN1 PAPPA LTBP2	1.55e-06	186	134	7	a832c1e0035bcd559722eccf262c145deb3494c7
ToppCell	(0)_MSCs-(00)_Lepr-MSC\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	CFH SHROOM3 ISM1 RSPO3 FBN1 PAPPA LTBP2	1.55e-06	186	134	7	f0d156167d7cc2cd8a76e5a364233e9f2170bc01
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 SHROOM3 KCNB2 ZNF608 NFIB LRP2 PAPPA	1.55e-06	186	134	7	b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell	Mesenchymal_cells-Adipo-CAR\|World / Lineage and Cell class	CFH SHROOM3 ISM1 APBB2 RSPO3 PAPPA LTBP2	1.55e-06	186	134	7	6ca8ce7ced91d6308b7c056032ffec1b37c974bf
ToppCell	Fibroblast-E_(Early_Fibroblastic_progenitor)\|World / shred on cell class and cell subclass (v4)	BRIP1 CENPE NSD2 SPAG5 FBN1 TACC3 PLK4	1.67e-06	188	134	7	be3db9768364568f44e32ae6b3bf99e49b0978bb
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CDC14A UBR5 SLCO2A1 CTBP2 CGNL1 PLCH1 UNC79	1.67e-06	188	134	7	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	Mesenchymal-myofibroblast_cell\|World / Lineage, Cell type, age group and donor	CFH ISM1 FBN1 NFIB PAPPA MYOCD LTBP2	1.73e-06	189	134	7	44e37f88137bb249933eb615235b2cf2ae7f3925
ToppCell	wk_15-18-Mesenchymal-Fibroblast-Airway_fibro\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CFH COL4A6 SERPINF1 ISM1 FBN1 NFIB LTBP2	1.73e-06	189	134	7	4f9608b84d135268a17455661870c46ae8554a24
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CNNM2 SH2D3C OLFM4 LAMC3 AFAP1L2 HMCN1 NGFR	1.73e-06	189	134	7	9c2492c38f27e4c699b40680652e4c64911cce52
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-Proliferating_T_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BRIP1 CENPE NSD2 TNFRSF18 SH2D2A TACC3 PLK4	1.79e-06	190	134	7	08420f0ecd2c62e102371d16dcb8eda0d510e92a
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BRIP1 CENPE NSD2 TNFRSF18 SH2D2A TACC3 PLK4	1.79e-06	190	134	7	f5a8b44d9948a16e2d5284c78d8f7ed422ac623a
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	SERPINF1 FBN1 HMCN1 NFIB MYOCD LTBP2 CGNL1	1.85e-06	191	134	7	9bbafdf316c1fa3a9f1ee30d41dd7158b5c97279
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRIP1 CENPE NSD2 TNFRSF18 SH2D2A TACC3 PLK4	1.85e-06	191	134	7	239300ff76f2c855b2b04d3002461158be90a01b
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH SERPINF1 ISM1 RSPO3 FBN1 NGFR LTBP2	1.85e-06	191	134	7	4e4488380379ed29d7898bae4e24221e7c67eb9d
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 LAMC3 FBN1 AFAP1L2 SLCO2A1 MMRN2 PCDH9	1.85e-06	191	134	7	b9ae5af426e7a1f2652a47700bb168371bd2dec6
ToppCell	LA\|World / Chamber and Cluster_Paper	PRUNE2 ZBTB7C SERPINF1 APBB2 FBN1 LRP2 LTBP2	1.99e-06	193	134	7	d4bf89437216baf489ea0239136dcedf3b6714af
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TBXAS1 BRIP1 SLCO2A1 MYOCD LTBP2 TACC3 PLK4	2.06e-06	194	134	7	590a9d4f054e6a3685daf752c9354650fcc7d18a
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH SERPINF1 LAMC3 RSPO3 FBN1 NGFR LTBP2	2.06e-06	194	134	7	02b8102be9414d6964cd71019613edff6d88b893
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH SERPINF1 ISM1 FBN1 HMCN1 PAPPA LTBP2	2.13e-06	195	134	7	51db90e7611f7d69980878c046505ff34212079b
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFH COL4A6 CUX2 OBSCN EFNA5 SLITRK5 NGFR	2.13e-06	195	134	7	6c9c58322c1df891bb4bab56dacb542c8777bb7d
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH CDC14A CLCA1 HMCN1 SLCO2A1 MMRN2 CGNL1	2.20e-06	196	134	7	dbf154b3d166ffd07be717dac8d8a3350ac63e16
ToppCell	Tracheal-10x3prime_v2-Stromal-Mesofibroblastic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CFH LRTM1 OLFM4 ZBTB49 HMCN1 USP32 LTBP2	2.28e-06	197	134	7	d7cef7881abd807a679432766ced609a6efd1067
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGAP24 ISM1 FBN1 HMCN1 NFIB CST3 LTBP2	2.28e-06	197	134	7	26475b9e4d6bfc0ae818dea13d139888ed7e92f1
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SERPINF1 FBN1 NFIB SLITRK5 NGFR PAPPA CGNL1	2.28e-06	197	134	7	6b6440f1baad5680cf9e13ca3ab72a2c65523d59
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGAP24 ISM1 FBN1 HMCN1 NFIB CST3 LTBP2	2.28e-06	197	134	7	155e63b33302a87393ace699b2f6d73abe9c5763
ToppCell	wk_20-22-Mesenchymal-Fibroblast-Airway_fibro\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CFH COL4A6 SERPINF1 FBN1 NFIB NGFR LTBP2	2.28e-06	197	134	7	233caeee200ca905900226f85426e084caf290fb
ToppCell	Tracheal-10x3prime_v2-Stromal-Mesofibroblastic-Mesothelia\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CFH LRTM1 OLFM4 ZBTB49 HMCN1 USP32 LTBP2	2.28e-06	197	134	7	20a5958512bdb99daeb8f4d244df53e4f048f879
ToppCell	COVID-19-Fibroblasts\|COVID-19 / group, cell type (main and fine annotations)	CFH APBB2 FBN1 HMCN1 NFIB PAPPA LTBP2	2.28e-06	197	134	7	fb847f2277609c31fffcdf49517243ce0684facf
ToppCell	LPS_only-Endothelial-Endothelial-FOXM1\|LPS_only / Treatment groups by lineage, cell group, cell type	BRIP1 CENPE NSD2 SPAG5 RSPO3 ZNF608 TACC3	2.28e-06	197	134	7	038fd92750257d43d5e980fd06d77742b543f11a
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SERPINF1 FBN1 NFIB SLITRK5 NGFR PAPPA CGNL1	2.35e-06	198	134	7	9541d68a1a6247dbd7161a62644eea6527c2c8ff
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGAP24 ISM1 FBN1 HMCN1 NFIB CST3 LTBP2	2.35e-06	198	134	7	a4005a49cf6709b543994ceb51ecd5dc46197fa9
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGAP24 ISM1 FBN1 HMCN1 NFIB CST3 LTBP2	2.35e-06	198	134	7	a699b365d3b6149f13f02b2e2ae9b6fdce761848
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRUNE2 COL4A6 LRTM1 KCNB2 SLCO5A1 MYOCD PCDH9	2.35e-06	198	134	7	c12e7511628db819a52959bb68580e27c00c2e41
ToppCell	tumor_Lung-Fibroblasts-COL14A1+_matrix_FBs\|tumor_Lung / Location, Cell class and cell subclass	CFH SERPINF1 ISM1 RSPO3 FBN1 NFIB PAPPA	2.35e-06	198	134	7	74f2c7ef702b25a5b99e56121229e678ed992524
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRUNE2 COL4A6 LRTM1 KCNB2 SLCO5A1 MYOCD PCDH9	2.35e-06	198	134	7	22e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCell	background-Hepatic_Stellate_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	LAMC3 RSPO3 FBN1 HMCN1 NGFR LTBP2 PCDH9	2.35e-06	198	134	7	bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CFH SERPINF1 ISM1 FBN1 HMCN1 PAPPA LTBP2	2.43e-06	199	134	7	e1f1950d6f840485e263b83dc81b98910be3ae7a
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-FOXM1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CCDC14 BRIP1 CENPE NSD2 SPAG5 MPHOSPH9 TACC3	2.43e-06	199	134	7	98575fcce726589e93fbb4df1aab03e57cb56076
ToppCell	(5)_Fibroblast-A_(Fibroblast_progenitors)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	CFH SERPINF1 OLFM4 RSPO3 FBN1 NFIB CST3	2.43e-06	199	134	7	b783917fe0a9725a680aa430a42f02ce294900ef
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFH PRUNE2 ISM1 RGL1 FBN1 LTBP2 PCDH9	2.52e-06	200	134	7	a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCell	Transplant_Alveoli_and_parenchyma-Mesenchymal\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	CFH SERPINF1 RSPO3 FBN1 NFIB PAPPA LTBP2	2.52e-06	200	134	7	954fee8425673e76198be414f5f6c4e3597c1919
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CFH SERPINF1 RSPO3 FBN1 HMCN1 PAPPA LTBP2	2.52e-06	200	134	7	6e3d1ae0ef84d3075afa40129a41169996462672
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFH ISM1 AHRR FBN1 HMCN1 PAPPA LTBP2	2.52e-06	200	134	7	58b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Vein\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ZBTB7C RSPO3 FBN1 AFAP1L2 HMCN1 SLCO2A1 MMRN2	2.52e-06	200	134	7	7eb366b2c5394af7c77650bde6261e7dac67154e
ToppCell	Tracheal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CFH SERPINF1 LAMC3 FBN1 HMCN1 PAPPA LTBP2	2.52e-06	200	134	7	8ab0051544ea32eb8b3f7f8ba7582deaf8bf26c0
ToppCell	(5)_Fibroblast-B_(Myofibroblast)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	CFH SERPINF1 ISM1 FBN1 HMCN1 LTBP2 HR	2.52e-06	200	134	7	9bbaa666d0f3b4782c1b4b95e0fa5fc1467842d8
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ARHGAP24 LRTM1 TEX26 NGFR CGNL1	3.88e-06	138	134	6	a88c3ae56b0af60f6e87cabade4f21e2bbb336f2
ToppCell	368C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)\|368C / Donor, Lineage, Cell class and subclass (all cells)	CFH SERPINF1 OLFM4 FBN1 CLCNKA CST3	6.77e-06	152	134	6	ee7855d76a49d07a032677a4dc83aa6116d50518
ToppCell	368C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	CFH SERPINF1 OLFM4 FBN1 CLCNKA CST3	6.77e-06	152	134	6	3a1414ba6a4972698c3262a00b124428835c35cb
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CNNM2 APBB2 EFNA5 HMCN1 CBY2 LTBP2	8.45e-06	158	134	6	7960337d87afecf2692ab65e5991f052ceddfacc
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF11 KCNB2 RIMBP3 SYCP1 MYOCD PLCH1	9.08e-06	160	134	6	f2cdee5a9e3b0eb125d6be7b5d239eb04333ae41
ToppCell	10x5'-Lung-Lymphocytic_T_CD4-Tnaive/CM_CD4\|Lung / Manually curated celltypes from each tissue	COL4A6 ISM1 CCDC187 LAMC3 PLCH1 FYB2	9.75e-06	162	134	6	91cc14aec8d580cf97a1929bc1acb00fcbcdb57a
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PRUNE2 COL4A6 ZBTB7C CLCNKA MYOCD IL4R	1.01e-05	163	134	6	1e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PRUNE2 COL4A6 ISM1 KCNB2 MYOCD LTBP2	1.05e-05	164	134	6	e3983f655cdba308fb192182829f17bef99ce0ba
ToppCell	PND14-Immune-Immune_Myeloid-Dendritic\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPE TNFRSF18 CST3 MPHOSPH9 TACC3 PLK4	1.20e-05	168	134	6	9b8a74abb83c64f0b5829dcb4275f722c82b45dc
ToppCell	COVID-19-Heart-Neuronal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ARHGAP24 IGSF11 SLITRK5 NGFR PAPPA PCDH9	1.20e-05	168	134	6	88c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCell	PND14-Immune-Immune_Myeloid-Dendritic-cDC1\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPE TNFRSF18 CST3 MPHOSPH9 TACC3 PLK4	1.20e-05	168	134	6	4b152b8d0f4a66faf664dfacb7914b18d60ce64a
ToppCell	PND14-Immune-Immune_Myeloid-Dendritic-cDC1-cDC1_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPE TNFRSF18 CST3 MPHOSPH9 TACC3 PLK4	1.20e-05	168	134	6	c3169ad8f4130ef18777ed86770bb722ffb5db85
ToppCell	NS-critical-d_0-4-Epithelial-Secretory\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFH SERPINF1 EFNA5 NFIB CGNL1 GOT1	1.24e-05	169	134	6	aec97583b23112060437b619cb429dc32f29285f
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFH SERPINF1 LAMC3 FBN1 EFNA5 NFIB	1.24e-05	169	134	6	031465190cd3623a25ef2b868daab8d932c8ff08
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH COL4A6 LAMB4 DLG5 SERPINF1 NGFR	1.28e-05	170	134	6	0cc20322cb3e3e7bbd4daad8785c99f80e355c16
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC2\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBXAS1 CENPE TEP1 SPAG5 CST3 TACC3	1.28e-05	170	134	6	9e94fa0d05abed3438b28296a293767096d517d6
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	TBXAS1 OBSCN SLCO5A1 EFNA5 INSYN2B MYOCD	1.28e-05	170	134	6	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH COL4A6 LAMB4 DLG5 SERPINF1 NGFR	1.28e-05	170	134	6	2d880223d01bde4bf777bd6f50b7d2768489075f
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARHGAP32 SHROOM3 CDC14A DLX4 PLK4 CFAP157	1.33e-05	171	134	6	1854a777d9eb9d3fc3ed3632332a6f89ce8131da
ToppCell	frontal_cortex-Non-neuronal-leptomeningeal_cell\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CFH COL4A6 SERPINF1 LAMC3 SLC6A12 CGNL1	1.33e-05	171	134	6	2e43fb129ee9bdc3b31febc43c10f959bf0f4a7d
ToppCell	frontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CFH COL4A6 SERPINF1 LAMC3 SLC6A12 CGNL1	1.33e-05	171	134	6	e219a1aa59a96e4bc3e2eacf985679174a51de41
ToppCell	normal_Pleural_Fluid-Myeloid_cells-CD1c+_DCs\|normal_Pleural_Fluid / Location, Cell class and cell subclass	SERPINF1 LRTM1 C15orf39 CST3 CTBP2 RASAL1	1.37e-05	172	134	6	200b2e63313b110b8ca59ee5b72c02cc8ed907cd
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Airway_fibro\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CFH ZBTB7C SERPINF1 ISM1 FBN1 NYAP1	1.42e-05	173	134	6	b23b408acc29a667cce104429afef1a6cf2720a5
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CFH COL4A6 ISM1 FBN1 NFIB LTBP2	1.42e-05	173	134	6	1f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCell	facs-Heart-RA-24m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH CDC14A CLCA1 HMCN1 MMRN2 CGNL1	1.46e-05	174	134	6	42dfb6f42b72e40e203b3ef341117bccf3553d54
ToppCell	primary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CFH COL4A6 SERPINF1 LAMC3 SLC6A12 CGNL1	1.46e-05	174	134	6	eade55f86ef1f7a5355ad65cec3aa6bfc5d3c62d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BRIP1 CENPE NSD2 ANKRD33 TACC3 PLK4	1.46e-05	174	134	6	84da9faff088d05233183b425385beb054c92d1b
ToppCell	primary_visual_cortex-Non-neuronal-leptomeningeal_cell\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CFH COL4A6 SERPINF1 LAMC3 SLC6A12 CGNL1	1.46e-05	174	134	6	2891ab2fd05eb4bbd239d1a2865f21ef7f2df39e
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	CCDC14 GALNT3 TTLL5 SLC35A2 USP32 RAI1	1.46e-05	174	134	6	2274648b80dd74f3c948a779bba3391095964c34
ToppCell	facs-Heart-RA-24m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH CDC14A CLCA1 HMCN1 MMRN2 CGNL1	1.46e-05	174	134	6	f04edf2ca6788875c9918611e416fb739924382e
Drug	Pirenzepine dihydrochloride [29868-97-1]; Down 200; 9.4uM; MCF7; HT_HG-U133A	DLG5 TTLL5 FNDC3A TEP1 PPP1R26 RNASEL SLC35A2 AGRN IL4R	2.20e-06	196	132	9	7226_DN
Drug	Phenformin hydrochloride [834-28-6]; Down 200; 16.6uM; MCF7; HT_HG-U133A	APBB2 CDC14A INKA2 RGL1 SLCO2A1 ZNF589 LRP2 MMRN2 PLK4	2.30e-06	197	132	9	3622_DN
Drug	funiferine N-oxide	TEP1 FBN1 LTBP2 TOP1MT AGRN	9.43e-06	49	132	5	CID000191631
Drug	Rgd Peptide	TBXAS1 LAMB4 FNDC3A LAMC3 ITGB7 RSPO3 FBN1 SLC35A2 PLK4	1.10e-05	239	132	9	CID000104802
Drug	Eg-6	TTLL5 NISCH NGFR	1.56e-05	9	132	3	CID000129611
Drug	Acyclovir [59277-89-3]; Down 200; 17.8uM; PC3; HT_HG-U133A	CEP104 ARHGAP24 GALNT3 OLFM4 APBB2 LAMC3 TEP1 PLCH1	1.94e-05	196	132	8	4683_DN
Drug	Cefotetan [69712-56-7]; Up 200; 7uM; HL60; HT_HG-U133A	TBXAS1 APBB2 FNDC3A SH2D2A CDC14A RGS14 ZNF589 PLK4	2.01e-05	197	132	8	1319_UP
Drug	Delsoline [509-18-2]; Down 200; 8.6uM; PC3; HT_HG-U133A	DLG5 BRIP1 APBB2 CDC14A NFIB ZNF589 SLITRK5 IL4R	2.08e-05	198	132	8	5858_DN
Drug	Acemetacin [53164-05-9]; Down 200; 9.6uM; HL60; HT_HG-U133A	ARHGAP32 TTLL5 CBL RGL1 SLC35A2 LRP2 DLX4 AGRN	2.08e-05	198	132	8	2411_DN
Drug	Bendroflumethiazide [73-48-3]; Up 200; 9.4uM; HL60; HT_HG-U133A	CUX2 EFNA5 CLCA1 ZNF589 NGFR LRP2 PAPPA LTBP2	2.16e-05	199	132	8	2555_UP
Drug	Kawain [500-64-1]; Up 200; 17.4uM; HL60; HT_HG-U133A	PRUNE2 CDC14A PPP1R26 EFNA5 SLCO2A1 LRP2 AGRN PLK4	2.16e-05	199	132	8	2337_UP
Disease	ephrin-A5 measurement	CFH EFNA5	1.96e-05	2	131	2	EFO_0020357
Disease	protocadherin-9 measurement	CFH PCDH9	1.96e-05	2	131	2	EFO_0802975
Disease	EMILIN-3 measurement	MMRN2 CHD6	5.85e-05	3	131	2	EFO_0801563
Disease	Weill-Marchesani syndrome	FBN1 LTBP2	5.85e-05	3	131	2	C0265313
Disease	Weill-Marchesani Syndrome, Autosomal Dominant	FBN1 LTBP2	5.85e-05	3	131	2	C1869115
Disease	Weill-Marchesani Syndrome, Autosomal Recessive	FBN1 LTBP2	5.85e-05	3	131	2	C1869114
Disease	Age-related macular degeneration	CFH HMCN1 CST3	6.65e-05	18	131	3	cv:C0242383
Disease	Colorectal Carcinoma	COL4A6 WRN OBSCN KCNB2 CDC14A FANCG SLCO2A1 LRP2 MMRN2 CTBP1 ZNF292 HR	7.21e-05	702	131	12	C0009402
Disease	Weill-Marchesani syndrome	FBN1 LTBP2	1.17e-04	4	131	2	cv:C0265313
Disease	Weill-Marchesani syndrome (is_implicated_in)	FBN1 LTBP2	1.17e-04	4	131	2	DOID:0050475 (is_implicated_in)
Disease	Leukemia, Myelocytic, Acute	BRIP1 NUP98 CBL FANCG CST3 AGRN	1.27e-04	173	131	6	C0023467
Disease	fibroblast growth factor receptor 3 measurement	CFH TACC3	1.94e-04	5	131	2	EFO_0020390
Disease	myocardial zonula adherens protein measurement	CFH CGNL1	1.94e-04	5	131	2	EFO_0802769
Disease	serum gamma-glutamyl transferase measurement	DLG5 CUX2 BRIP1 ZBTB7C GALNT3 IFT172 RSPO3 GPBP1L1 EFNA5 NFIB CGNL1 PRRC2A ZNF292	2.23e-04	914	131	13	EFO_0004532
Disease	aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement	IQCN KCNB2 RSPO3 NFIB POC5 UNC79 PRRC2A HR	2.30e-04	364	131	8	EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Disease	4p partial monosomy syndrome	NSD2 CTBP1	2.90e-04	6	131	2	cv:C1956097
Disease	WOLF-HIRSCHHORN SYNDROME	NSD2 CTBP1	2.90e-04	6	131	2	194190
Disease	Eye Diseases, Hereditary	LRP2 PLK4	2.90e-04	6	131	2	C0015398
Disease	nischarin measurement	CFH NISCH	2.90e-04	6	131	2	EFO_0801841
Disease	riboflavin kinase measurement	CFH PRUNE2	2.90e-04	6	131	2	EFO_0802016
Disease	fear of pain measurement	MYOCD TRMT12	2.90e-04	6	131	2	EFO_0008330
Disease	r-spondin-3 measurement	CFH RSPO3	4.05e-04	7	131	2	EFO_0021878
Disease	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 measurement	CFH MMRN2	4.05e-04	7	131	2	EFO_0020108
Disease	cystatin C measurement	SHROOM3 CUX2 FNDC3A RGS14 NFIB CST3 LRP2 CGNL1	4.46e-04	402	131	8	EFO_0004617
Disease	Pitt-Rogers-Danks Syndrome	NSD2 CTBP1	5.38e-04	8	131	2	C0796117
Disease	Kidney Diseases	CNNM2 CST3 LRP2 RASAL1	6.48e-04	88	131	4	C0022658
Disease	Uveitis	SERPINF1 CRYBB2	6.90e-04	9	131	2	C0042164
Disease	beta-mannosidase measurement	CFH GOLGA5	6.90e-04	9	131	2	EFO_0801421
Disease	Wolf-Hirschhorn Syndrome	NSD2 CTBP1	6.90e-04	9	131	2	C1956097
Disease	insomnia measurement	CNNM2 OLFM4 KCNB2 EFNA5 UBR5 NFIB PLCH1 PCDH9	8.40e-04	443	131	8	EFO_0007876
Disease	transient cerebral ischemia (is_implicated_in)	SERPINF1 GOT1	1.05e-03	11	131	2	DOID:224 (is_implicated_in)
Disease	Marfan Syndrome	FBN1 LTBP2	1.05e-03	11	131	2	C0024796
Disease	cervical carcinoma	TBXAS1 PRUNE2 TEP1 SLCO5A1 PRRC2A	1.34e-03	182	131	5	EFO_0001061
Disease	visceral adipose tissue measurement	BRIP1 IQCN KCNB2 RSPO3 SLITRK5 POC5 UNC79 PRRC2A	1.42e-03	481	131	8	EFO_0004765
Disease	body fat percentage	IQCN KCNB2 RSPO3 NFIB POC5 UNC79 PRRC2A HR	1.55e-03	488	131	8	EFO_0007800
Disease	macula measurement	ARHGAP32 DLG5 FBN1 LRP2 CGNL1	1.59e-03	189	131	5	EFO_0008375
Disease	membranous glomerulonephritis (biomarker_via_orthology)	CFH LRP2	1.72e-03	14	131	2	DOID:10976 (biomarker_via_orthology)
Disease	Fanconi anemia	BRIP1 FANCG	1.72e-03	14	131	2	cv:C0015625
Disease	serum alanine aminotransferase measurement	CFH DLG5 SHROOM3 CUX2 BRIP1 ZBTB7C IQCN RSPO3 FBN1 EFNA5 ADGRA1	1.75e-03	869	131	11	EFO_0004735
Disease	Prostatic Neoplasms	TBXAS1 GALNT3 SERPINF1 RNASEL NGFR LRP2 CTBP2 CHD6 ZNF292	1.76e-03	616	131	9	C0033578
Disease	Malignant neoplasm of prostate	TBXAS1 GALNT3 SERPINF1 RNASEL NGFR LRP2 CTBP2 CHD6 ZNF292	1.76e-03	616	131	9	C0376358
Disease	serum urea measurement	SHROOM3 ZBTB7C CDC14A RSPO3 RGS14	1.82e-03	195	131	5	EFO_0009795
Disease	glycerate measurement	HMCN1 AGRN	1.98e-03	15	131	2	EFO_0021029
Disease	hippocampal atrophy	PRUNE2 EFNA5 CHD6	2.00e-03	56	131	3	EFO_0005039
Disease	aspartate aminotransferase measurement	CFH DLG5 SHROOM3 CUX2 BRIP1 OBSCN RSPO3 RGL1 EFNA5 PRRC2A GOT1	2.37e-03	904	131	11	EFO_0004736
Disease	hypertension (implicated_via_orthology)	TBXAS1 NISCH NGFR LRP2	2.59e-03	128	131	4	DOID:10763 (implicated_via_orthology)
Disease	cortical surface area measurement	SHROOM3 CNNM2 LAMC3 CNOT6 RSPO3 FBN1 EFNA5 NFIB PAPPA CTBP2 MPHOSPH9 TACC3 PRRC2A AGAP3	2.66e-03	1345	131	14	EFO_0010736
Disease	Bone marrow hypocellularity	BRIP1 FANCG	2.86e-03	18	131	2	C1855710
Disease	wheezing	CBL KRBA1 NFIB	3.06e-03	65	131	3	EFO_0009715
Disease	Meningioma	WRN CST3	3.18e-03	19	131	2	C0025286
Disease	hearing loss	AHRR GPBP1L1 CTBP2	3.33e-03	67	131	3	EFO_0004238
Disease	Microcephaly	NSD2 PLK4 ZNF292	3.33e-03	67	131	3	C0025958
Disease	MYELODYSPLASTIC SYNDROME	BRIP1 CBL FANCG	3.33e-03	67	131	3	C3463824
Disease	coronary artery disease (is_marker_for)	CST3 NGFR PAPPA	3.33e-03	67	131	3	DOID:3393 (is_marker_for)
Disease	renal system measurement	SHROOM3 RGS14	3.53e-03	20	131	2	EFO_0004742
Disease	maximal midexpiratory flow rate	BRIP1 IGSF11	3.53e-03	20	131	2	EFO_0004313
Disease	Intellectual Disability	CUX2 NSD2 NFIB SLC35A2 LRP2 RAI1 ZNF292	3.90e-03	447	131	7	C3714756
Disease	blood urea nitrogen measurement	SHROOM3 CUX2 ZBTB7C CDC14A RSPO3 RGS14 LRP2	4.15e-03	452	131	7	EFO_0004741
Disease	albumin:globulin ratio measurement	IGSF11 MPHOSPH9 PRRC2A	4.24e-03	73	131	3	EFO_0005128
Disease	multiple sclerosis (is_implicated_in)	SH2D2A MPHOSPH9 IL4R	4.24e-03	73	131	3	DOID:2377 (is_implicated_in)
Disease	Seckel syndrome	CENPE PLK4	4.26e-03	22	131	2	C0265202
Disease	portal hypertension (biomarker_via_orthology)	SERPINF1 NGFR	4.26e-03	22	131	2	DOID:10762 (biomarker_via_orthology)
Disease	nephrosis (biomarker_via_orthology)	CFH LRP2	4.26e-03	22	131	2	DOID:2527 (biomarker_via_orthology)
Disease	psychotic symptoms	ARID4B EFNA5 PLCH1	4.41e-03	74	131	3	EFO_0005940

Protein segments in the cluster

Peptide	Gene	Start	Entry
KVSSHCNEGTRPPLP	USP26	546	Q9BXU7
TDGLPQSEPPHQLCA	AHRR	626	A9YTQ3
GPCKSLPNSPSHSAV	AGAP3	261	Q96P47
SNQPEPEHPEKACTG	ARID4B	1101	Q4LE39
SCSKQQLPNVPHSLP	AMIGO1	46	Q86WK6
VKHSQSEQVPPCPIG	COL4A6	1471	Q14031
SHELNGPCPNLKETG	CRYBB2	31	P43320
TPQPCHKNSQRQGPF	CCDC187	16	A0A096LP49
HPQDSSSCEILPSQP	APBB2	141	Q92870
QGPLKDAPNLICTPH	CTBP1	301	Q13363
APSPNQPTKHGDNRE	CTBP2	426	P56545
NLNSPPGPHSAKTEE	CDC14A	546	Q9UNH5
NNTLTPQPCHQGPSV	GUSBP11	176	Q6P575
RAIPSKHQGPCDQAP	AGRN	451	O00468
AHPPGPCKMTNLQAA	ADGRA1	356	Q86SQ6
LPNGEPSQHSSAPQK	AFAP1L2	81	Q8N4X5
EKIPCSQPPQIEHGT	CFH	866	P08603
PDCPSLHPQQESEAG	CUX2	1356	O14529
SKNIPNGIPAVPCHA	CCDC14	226	Q49A88
AALSQPLCGPAEHPQ	DLX4	76	Q92988
CPHQESQSHGPPKES	CFAP157	421	Q5JU67
PPPAPASSQKCHVVN	ATXN7L2	116	Q5T6C5
SAPNPNKLAACHPGA	RASAL1	671	O95294
CTVVNSPGDAPKPHR	RAI1	1611	Q7Z5J4
QSGSPSHNDPAKNPP	NFIB	191	O00712
SHQCQPKPSPSGHQS	ANKRD33	411	Q7Z3H0
LSSPPSCNNNPKIHK	RGL1	611	Q9NZL6
KASPHNPGSCGEPQA	RIMBP3B	1226	A6NNM3
KASPHNPGSCGEPQA	RIMBP3C	1226	A6NJZ7
PNTSGSIHENPPKAK	IQCN	541	Q9H0B3
PCASQSSHPKGELVP	POC5	46	Q8NA72
PIPQTPESAGNKHSN	NUP98	666	P52948
ASSLQPPCHCGKPLQ	KRBA1	786	A5PL33
CSQQGLAEIPSHLPP	LRTM1	36	Q9HBL6
GENPPTSCPKALEHS	INKA2	271	Q9NTI7
SLNPEAGKQHQPCRP	GPBP1L1	161	Q9HC44
KFLIHSQQPCPQGAP	MMRN2	76	Q9H8L6
AACPDHTPTPNDDGK	GOLGA5	206	Q8TBA6
EVNKASGPRACPPSH	HR	361	O43593
PTPQPSCNGDTHRTK	HR	716	O43593
HSKSDNIPVTPQKCP	PCDH9	1016	Q9HC56
SCHASNPSNPRPSKG	NSD2	766	O96028
HSECSTPPQSPLNID	DLG5	1296	Q8TDM6
NHSSCPEPVPNGVKK	MPHOSPH9	906	Q99550
AVHPSKQPNSVNPCA	LRP2	1691	P98164
PPDLASPLHCGTQSQ	FANCG	331	O15287
NDTNPAPKHKSCGDP	PAPPA	601	Q13219
NNAPGNCDHPLPETT	ARHGAP32	1111	A7KAX9
PQCSPQHSPLGAVKS	MYOCD	631	Q8IZQ8
QVPKPCAHQCSNTPG	HMCN1	5321	Q96RW7
SGESQGKLVNHPCPP	IFT172	186	Q9UG01
QPAPSCQKCILSHPS	ITGB7	46	P26010
KINSFSPQKPPGHCS	BRIP1	201	Q9BX63
PAPFCHPKQGSAPQE	OBSCN	7031	Q5VST9
PGNKVSEHPCNEENP	ARHGAP24	66	Q8N264
SPHEEPCSPGLLQDQ	CBY2	286	Q8NA61
LQPLARSGSPCHQKP	CEP104	306	O60308
PCLSPDAQPPNNIHS	IL31	71	Q6EBC2
LVPPSAPHCQIQGSQ	IGSF11	141	Q5DX21
HPAPGNAQSSSQTPK	IL4R	796	P24394
EITKTQPHSHPNPDC	KCNB2	546	Q92953
KGDNPNSHPEPAPSC	CHD6	2661	Q8TD26
CAHSRPPQPNIDGKV	CGNL1	456	Q0VF96
PPGHQLSPNISACID	FBN1	1141	P35555
EHPSLVSCNPSDPLQ	GALNT3	611	Q14435
SSPQKCPSPINEHNG	FNDC3A	206	Q9Y2H6
VPQKTNPADPISHCN	CENPJ	621	Q9HC77
ACAHNPTGIDPTPEQ	GOT1	191	P17174
NSTGKFCHLPIPQPD	LTBP2	421	Q14767
CLPSVQPTLPNGSEH	MC3R	6	P41968
CHPPVKVIQSQDGFP	DSC1	471	Q08554
ECNRPHSPNGPLKFS	EFNA5	101	P52803
NPPGGSEHCIPKTLQ	LAMB4	641	A4D0S4
NPDLTGLCEPTPQDH	CBL	346	P22681
ARPPNNGQKCTESPS	ISM1	436	B1AKI9
SEHTDPQPSNKPLTC	CENPE	2516	Q02224
KTQPNLDNCPFHDQP	CST3	101	P01034
ENNISGCPHPLIPSD	CNOT6	516	Q9ULM6
AQCKVPSPPTQHPEA	PCARE	1066	A6NGG8
CHSKEPAGSTPAPQV	NYAP1	361	Q6ZVC0
PATEEPGPCLSQQLH	TACC3	451	Q9Y6A5
SCPGSEPVPTHQQGQ	TACC3	501	Q9Y6A5
PPNPCSEQLHCSKES	SPAG5	206	Q96R06
EKSPLPNTSPQGTNH	PRUNE2	746	Q8WUY3
AQICPQGSHEAPIPT	SH2D2A	6	Q9NP31
GTPNCKAELHGPFNP	TDRD9	1141	Q8NDG6
KASPHNPGSCGEPQA	RIMBP3	1226	Q9UFD9
TNPCPEGPKLARHSQ	FYB2	446	Q5VWT5
DSSLPQPKQHPCLDG	SLC6A12	576	P48065
PQSKNLDSGHCVPEP	PRRC2A	1811	P48634
FPQTHSPNKPQCDGA	RNASEL	716	Q05823
LEPPACPKDSGGNNH	SLCO5A1	246	Q9H2Y9
TPPQGNSPHSNERKS	SHROOM3	576	Q8TF72
PATPCRPSEAAQNKG	PPP1R26	321	Q5T8A7
KHGPDSGLQPSCDVN	WRN	1356	Q14191
NGTCSHPLIPDKASP	IARS2	361	Q9NSE4
NPSDSGKCPNVLNDP	SI	56	P14410
QALSNHLCPGKTPFP	PLK4	451	O00444
CEASKDQNTPVVHPP	OLFM4	226	Q6UX06
ASASASGPCVHQQPP	SLC35A2	351	P78381
TTKEPCHSKVPQPGN	SPRR3	36	Q9UBC9
KEPSTKGLNPNPSHQ	CHRM5	411	P08912
SPDETSAPCPNIHIN	CLCA1	876	A8K7I4
EPPSRAPGHQQCLQD	CLCNKA	606	P51800
DQPSPCPQLLDSQSH	C15orf39	1031	Q6ZRI6
ENKSPPRPCGLNHSD	CNNM2	746	Q9H8M5
PPSKCHSTTQNPQKE	SLCO2A1	151	Q92959
STGCKPNPSRQHQPS	TBXAS1	306	P24557
ANADRLCPKSNPQGP	TEP1	686	Q99973
HSSCQNPASPPEEGS	SERPINF1	16	P36955
PDKHCSTTPAGNSLP	SLITRK5	861	O94991
NQTPPPEGEKLHSDS	NGFR	291	P08138
NNNPPASHLCVKTPK	SYCP1	916	Q15431
SEENQIPSHLPACPS	NISCH	1116	Q9Y2I1
GNPACSAQLQHVSPP	ZNF292	1176	O60281
NCSRDSKIPEPPAGH	TOP1MT	221	Q969P6
QHPSAKGNLCPPTNE	RSPO3	181	Q9BXY4
QDSSPGPALPCHKIS	SERPINA13P	36	Q6UXR4
QGCPPRTQDKATHPP	RGS14	461	O43566
ENPCPSKSLSPKQHL	PLCH1	1076	Q4KWH8
NKTHNAVCVPGSPPA	TNFRSF18	146	Q9Y5U5
GQCQPTVSPHSETAP	ULK2	386	Q8IYT8
NLPDPQDISCHQSPS	ZBTB7C	176	A1YPR0
APSTPEPNKNHSKLG	ZNF608	1156	Q9ULD9
SSEPQLCPGSAPKTH	SH2D3C	446	Q8N5H7
DPVPSKRAQGCSPAQ	TRMT12	91	Q53H54
PHPESDATCQQPVKQ	ZBTB49	286	Q6ZSB9
HDPLSLCKACNPQPN	PLBD2	486	Q8NHP8
PSLCHHNLQPTDDPN	TEX26	11	Q8N6G2
PCPEDQPQSQHPSDK	ZNF589	121	Q86UQ0
SPLPPQEASNHAQDC	USP32	1131	Q8NFA0
ASASPCLHPGAQNIP	TTLL5	941	Q6EMB2
SCASLVPKPPPNHEQ	TTLL5	1221	Q6EMB2
RGSPKQDSPCIHPSE	ZBTB26	156	Q9HCK0
PPDDQHLPTANTCIS	UBR5	2756	O95071
PASKHGENPGNCTEP	UNC79	916	Q9P2D8
DTLEFPNCPGSNHLP	INSYN2B	366	A6NMK8
PLGSQEDQCHPKTGQ	LAMC3	921	Q9Y6N6