Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionSMAD binding

TGFB1I1 SKOR2 SMAD6

2.88e-0486303GO:0046332
GeneOntologyMolecularFunctionI-SMAD binding

TGFB1I1 SMAD6

2.93e-0417302GO:0070411
GeneOntologyMolecularFunctionfolic acid binding

IZUMO1R FOLR1

4.08e-0420302GO:0005542
GeneOntologyMolecularFunctiontransmembrane receptor protein serine/threonine kinase binding

ELAPOR2 SMAD6

7.48e-0427302GO:0070696
GeneOntologyMolecularFunctionreceptor serine/threonine kinase binding

ELAPOR2 SMAD6

1.26e-0335302GO:0033612
GeneOntologyMolecularFunctionextracellular matrix structural constituent

LAMA5 COL22A1 FBN3

2.77e-03188303GO:0005201
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

TGFB1I1 ELAPOR2 FOLR1 ITGB6 NOTCH1 SKOR2 SMAD6

2.15e-06445297GO:0141091
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

TGFB1I1 ELAPOR2 FOLR1 ITGB6 NOTCH1 SKOR2 SMAD6

3.64e-06482297GO:0007178
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

TGFB1I1 ELAPOR2 FOLR1 NOTCH1 SKOR2 SMAD6

7.44e-06347296GO:0090092
GeneOntologyBiologicalProcesscardiac vascular smooth muscle cell development

NOTCH1 SMAD6

1.90e-055292GO:0060948
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

TGFB1I1 ELAPOR2 FOLR1 NOTCH1 SKOR2 SMAD6

1.97e-05412296GO:0090287
GeneOntologyBiologicalProcessregulation of BMP signaling pathway

ELAPOR2 NOTCH1 SKOR2 SMAD6

3.26e-05131294GO:0030510
GeneOntologyBiologicalProcesstransforming growth factor beta receptor signaling pathway

TGFB1I1 FOLR1 ITGB6 SKOR2 SMAD6

3.78e-05276295GO:0007179
GeneOntologyBiologicalProcesscellular response to transforming growth factor beta stimulus

TGFB1I1 FOLR1 ITGB6 SKOR2 SMAD6

9.59e-05336295GO:0071560
GeneOntologyBiologicalProcessresponse to transforming growth factor beta

TGFB1I1 FOLR1 ITGB6 SKOR2 SMAD6

1.06e-04343295GO:0071559
GeneOntologyBiologicalProcesserror-prone translesion synthesis

POLD2 POLE2

1.25e-0412292GO:0042276
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

TGFB1I1 ELAPOR2 FOLR1 ITGB6 NOTCH1 SKOR2 SMAD6

1.39e-04850297GO:0071363
GeneOntologyBiologicalProcessregulation of transforming growth factor beta receptor signaling pathway

TGFB1I1 FOLR1 SKOR2 SMAD6

1.44e-04192294GO:0017015
GeneOntologyBiologicalProcessregulation of cellular response to transforming growth factor beta stimulus

TGFB1I1 FOLR1 SKOR2 SMAD6

1.53e-04195294GO:1903844
GeneOntologyBiologicalProcessBMP signaling pathway

ELAPOR2 NOTCH1 SKOR2 SMAD6

1.59e-04197294GO:0030509
GeneOntologyBiologicalProcessresponse to growth factor

TGFB1I1 ELAPOR2 FOLR1 ITGB6 NOTCH1 SKOR2 SMAD6

1.76e-04883297GO:0070848
GeneOntologyBiologicalProcessnegative regulation of BMP signaling pathway

NOTCH1 SKOR2 SMAD6

1.91e-0480293GO:0030514
GeneOntologyBiologicalProcessmitral valve morphogenesis

NOTCH1 SMAD6

1.98e-0415292GO:0003183
GeneOntologyBiologicalProcessvascular associated smooth muscle cell development

NOTCH1 SMAD6

1.98e-0415292GO:0097084
GeneOntologyBiologicalProcessresponse to BMP

ELAPOR2 NOTCH1 SKOR2 SMAD6

2.22e-04215294GO:0071772
GeneOntologyBiologicalProcesscellular response to BMP stimulus

ELAPOR2 NOTCH1 SKOR2 SMAD6

2.22e-04215294GO:0071773
GeneOntologyBiologicalProcessmitral valve development

NOTCH1 SMAD6

2.26e-0416292GO:0003174
GeneOntologyBiologicalProcesscell-substrate adhesion

FZD7 LAMA5 ITGB6 NOTCH1 SMAD6

2.43e-04410295GO:0031589
GeneOntologyBiologicalProcesscardiocyte differentiation

FZD7 FOLR1 NOTCH1 SMAD6

2.47e-04221294GO:0035051
GeneOntologyBiologicalProcesssomatic stem cell division

FZD7 NOTCH1

2.56e-0417292GO:0048103
GeneOntologyBiologicalProcesscardiac vascular smooth muscle cell differentiation

NOTCH1 SMAD6

2.88e-0418292GO:0060947
GeneOntologyBiologicalProcessoutflow tract morphogenesis

FOLR1 NOTCH1 SMAD6

3.07e-0494293GO:0003151
GeneOntologyBiologicalProcesspulmonary valve morphogenesis

NOTCH1 SMAD6

3.57e-0420292GO:0003184
GeneOntologyBiologicalProcessregulation of cell-cell adhesion mediated by cadherin

ADAM19 NOTCH1

3.94e-0421292GO:2000047
GeneOntologyBiologicalProcesscell migration involved in heart development

FOLR1 NOTCH1

4.33e-0422292GO:0060973
GeneOntologyBiologicalProcesspulmonary valve development

NOTCH1 SMAD6

5.17e-0424292GO:0003177
GeneOntologyBiologicalProcesspositive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

TGFB1I1 ELAPOR2 NOTCH1

5.55e-04115293GO:0090100
GeneOntologyBiologicalProcesstranslesion synthesis

POLD2 POLE2

6.07e-0426292GO:0019985
GeneOntologyBiologicalProcessatrioventricular valve morphogenesis

NOTCH1 SMAD6

7.05e-0428292GO:0003181
GeneOntologyBiologicalProcessmesenchymal cell differentiation

TGFB1I1 LAMA5 FOLR1 NOTCH1

7.44e-04296294GO:0048762
GeneOntologyBiologicalProcessartery development

FOLR1 NOTCH1 SMAD6

8.47e-04133293GO:0060840
GeneOntologyBiologicalProcessatrioventricular valve development

NOTCH1 SMAD6

9.22e-0432292GO:0003171
GeneOntologyBiologicalProcessfusion of sperm to egg plasma membrane involved in single fertilization

IZUMO1R FOLR1

9.81e-0433292GO:0007342
GeneOntologyBiologicalProcesspositive regulation of epidermis development

ELAPOR2 NOTCH1

9.81e-0433292GO:0045684
GeneOntologyBiologicalProcesscoronary vasculature morphogenesis

NOTCH1 SMAD6

1.04e-0334292GO:0060977
GeneOntologyBiologicalProcessenzyme-linked receptor protein signaling pathway

TGFB1I1 ELAPOR2 FOLR1 ITGB6 NOTCH1 SKOR2 SMAD6

1.04e-031186297GO:0007167
GeneOntologyBiologicalProcessheart formation

FOLR1 NOTCH1

1.17e-0336292GO:0060914
GeneOntologyBiologicalProcessnegative regulation of cellular response to growth factor stimulus

NOTCH1 SKOR2 SMAD6

1.20e-03150293GO:0090288
GeneOntologyBiologicalProcesscell fate commitment

TGFB1I1 FZD7 GSX1 NOTCH1

1.22e-03338294GO:0045165
GeneOntologyBiologicalProcessplasma membrane fusion

IZUMO1R FOLR1

1.23e-0337292GO:0045026
GeneOntologyBiologicalProcesspostreplication repair

POLD2 POLE2

1.30e-0338292GO:0006301
GeneOntologyBiologicalProcessaortic valve morphogenesis

NOTCH1 SMAD6

1.37e-0339292GO:0003180
GeneOntologyBiologicalProcesskidney epithelium development

LAMA5 NOTCH1 SMAD6

1.50e-03162293GO:0072073
GeneOntologyBiologicalProcesspositive regulation of BMP signaling pathway

ELAPOR2 NOTCH1

1.59e-0342292GO:0030513
GeneOntologyBiologicalProcessmesenchyme development

TGFB1I1 LAMA5 FOLR1 NOTCH1

1.73e-03372294GO:0060485
GeneOntologyBiologicalProcessaortic valve development

NOTCH1 SMAD6

1.90e-0346292GO:0003176
GeneOntologyBiologicalProcessDNA synthesis involved in DNA repair

POLD2 POLE2

2.07e-0348292GO:0000731
GeneOntologyBiologicalProcessstem cell division

FZD7 NOTCH1

2.15e-0349292GO:0017145
GeneOntologyBiologicalProcessnegative regulation of ossification

NOTCH1 SMAD6

2.24e-0350292GO:0030279
GeneOntologyBiologicalProcesssemi-lunar valve development

NOTCH1 SMAD6

2.24e-0350292GO:1905314
GeneOntologyBiologicalProcesscell-cell adhesion mediated by cadherin

ADAM19 NOTCH1

2.24e-0350292GO:0044331
GeneOntologyBiologicalProcessnegative regulation of striated muscle cell differentiation

FZD7 NOTCH1

2.33e-0351292GO:0051154
GeneOntologyBiologicalProcessmorphogenesis of embryonic epithelium

TGFB1I1 LAMA5 FOLR1

2.36e-03190293GO:0016331
GeneOntologyBiologicalProcessvascular associated smooth muscle cell differentiation

NOTCH1 SMAD6

2.71e-0355292GO:0035886
GeneOntologyBiologicalProcessembryonic morphogenesis

TGFB1I1 FZD7 LAMA5 FOLR1 NOTCH1

2.90e-03713295GO:0048598
GeneOntologyBiologicalProcesstrabecula morphogenesis

PPARGC1B NOTCH1

2.90e-0357292GO:0061383
GeneOntologyCellularComponentextracellular matrix

TGFB1I1 LAMA5 MUC5B COL22A1 ADAM19 FCGBP FBN3

3.15e-05656307GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

TGFB1I1 LAMA5 MUC5B COL22A1 ADAM19 FCGBP FBN3

3.21e-05658307GO:0030312
GeneOntologyCellularComponentDNA polymerase complex

POLD2 POLE2

3.72e-0420302GO:0042575
HumanPhenoThoracic aorta calcification

NOTCH1 SMAD6

3.46e-055102HP:0004962
DomainDNA_pol_alpha/epsilon_bsu

POLD2 POLE2

7.48e-063302IPR007185
DomainDNA_pol_E_B

POLD2 POLE2

7.48e-063302PF04042
DomainFolate_rcpt

IZUMO1R FOLR1

2.49e-055302IPR004269
DomainEGF-like_dom

LAMA5 ADAM19 FCGBP FBN3 NOTCH1

4.39e-05249305IPR000742
DomainEGF_1

LAMA5 ADAM19 ITGB6 FBN3 NOTCH1

4.92e-05255305PS00022
DomainEGF-like_CS

LAMA5 ADAM19 ITGB6 FBN3 NOTCH1

5.49e-05261305IPR013032
DomainEGF_2

LAMA5 ADAM19 ITGB6 FBN3 NOTCH1

5.90e-05265305PS01186
DomainFolate_rcpt-like

IZUMO1R FOLR1

6.94e-058302IPR018143
DomainFolate_rec

IZUMO1R FOLR1

6.94e-058302PF03024
DomainGrowth_fac_rcpt_

LAMA5 ELAPOR2 FBN3 NOTCH1

1.08e-04156304IPR009030
DomainEGF_extracell

ADAM19 ITGB6 NOTCH1

1.20e-0460303IPR013111
DomainEGF_2

ADAM19 ITGB6 NOTCH1

1.20e-0460303PF07974
DomainTIL

MUC5B FCGBP

1.63e-0412302PF01826
DomainC8

MUC5B FCGBP

1.63e-0412302PF08742
DomainUnchr_dom_Cys-rich

MUC5B FCGBP

1.92e-0413302IPR014853
DomainC8

MUC5B FCGBP

1.92e-0413302SM00832
DomainTIL_dom

MUC5B FCGBP

2.24e-0414302IPR002919
DomainVWFD

MUC5B FCGBP

2.95e-0416302PS51233
DomainVWD

MUC5B FCGBP

2.95e-0416302SM00216
DomainVWF_type-D

MUC5B FCGBP

2.95e-0416302IPR001846
DomainVWD

MUC5B FCGBP

2.95e-0416302PF00094
DomainVWC_out

MUC5B FCGBP

4.19e-0419302SM00215
DomainEGF

LAMA5 FCGBP FBN3 NOTCH1

5.18e-04235304SM00181
DomainhEGF

FBN3 NOTCH1

9.19e-0428302PF12661
DomainVWC

MUC5B FCGBP

1.69e-0338302SM00214
DomainVWF_dom

MUC5B FCGBP

2.06e-0342302IPR001007
DomainLaminin_G

LAMA5 COL22A1

3.90e-0358302IPR001791
DomainConA-like_dom

LAMA5 COL22A1 SPRYD7

5.11e-03219303IPR013320
DomainEGF_3

ADAM19 FBN3 NOTCH1

6.21e-03235303PS50026
Domain-

COL22A1 ITGB6

6.27e-03743023.40.50.410
DomainVWFA

COL22A1 ITGB6

7.65e-0382302PS50234
DomainVWA

COL22A1 ITGB6

8.01e-0384302SM00327
DomainEGF_CA

FBN3 NOTCH1

8.38e-0386302PF07645
DomainEGF_Ca-bd_CS

FBN3 NOTCH1

1.06e-0297302IPR018097
DomainEGF_CA

FBN3 NOTCH1

1.10e-0299302PS01187
DomainVWF_A

COL22A1 ITGB6

1.10e-0299302IPR002035
DomainASX_HYDROXYL

FBN3 NOTCH1

1.12e-02100302PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

FBN3 NOTCH1

1.25e-02106302IPR000152
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

LAMA5 COL22A1 ADAM19 ITGB6 FBN3

8.26e-05300225M610
PathwayKEGG_MEDICUS_REFERENCE_LONG_PATCH_BER

POLD2 POLE2

3.12e-0417222M47831
PathwayREACTOME_PCNA_DEPENDENT_LONG_PATCH_BASE_EXCISION_REPAIR

POLD2 POLE2

4.80e-0421222M27505
PathwayREACTOME_PCNA_DEPENDENT_LONG_PATCH_BASE_EXCISION_REPAIR

POLD2 POLE2

4.80e-0421222MM15230
PathwayREACTOME_GAP_FILLING_DNA_REPAIR_SYNTHESIS_AND_LIGATION_IN_GG_NER

POLD2 POLE2

5.27e-0422222MM15303
PathwayWP_DNA_MISMATCH_REPAIR

POLD2 POLE2

5.77e-0423222M39668
PathwayREACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_MULTIPLE_NUCLEOTIDE_PATCH_REPLACEMENT_PATHWAY

POLD2 POLE2

6.82e-0425222M541
PathwayREACTOME_GAP_FILLING_DNA_REPAIR_SYNTHESIS_AND_LIGATION_IN_GG_NER

POLD2 POLE2

6.82e-0425222M27593
PathwayREACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_MULTIPLE_NUCLEOTIDE_PATCH_REPLACEMENT_PATHWAY

POLD2 POLE2

7.39e-0426222MM14481
PathwayKEGG_MEDICUS_REFERENCE_MISMATCH_REPAIR

POLD2 POLE2

7.39e-0426222M47827
PathwayKEGG_MEDICUS_REFERENCE_CORE_NER_REACTION

POLD2 POLE2

9.20e-0429222M47826
PathwayREACTOME_RECOGNITION_OF_DNA_DAMAGE_BY_PCNA_CONTAINING_REPLICATION_COMPLEX

POLD2 POLE2

9.85e-0430222M26898
PathwayREACTOME_RECOGNITION_OF_DNA_DAMAGE_BY_PCNA_CONTAINING_REPLICATION_COMPLEX

POLD2 POLE2

9.85e-0430222MM14476
PathwayWP_BASE_EXCISION_REPAIR

POLD2 POLE2

1.05e-0331222M39861
PathwayREACTOME_TERMINATION_OF_TRANSLESION_DNA_SYNTHESIS

POLD2 POLE2

1.12e-0332222M27538
PathwayREACTOME_TERMINATION_OF_TRANSLESION_DNA_SYNTHESIS

POLD2 POLE2

1.12e-0332222MM15260
PathwayKEGG_MEDICUS_REFERENCE_HOMOLOGOUS_RECOMBINATION

POLD2 POLE2

1.19e-0333222M47842
PathwayKEGG_BASE_EXCISION_REPAIR

POLD2 POLE2

1.34e-0335222M5500
PathwayKEGG_DNA_REPLICATION

POLD2 POLE2

1.42e-0336222M16853
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

ITGB6 FBN3

1.50e-0337222M27134
PathwayREACTOME_RESOLUTION_OF_ABASIC_SITES_AP_SITES

POLD2 POLE2

1.58e-0338222M27701
PathwayREACTOME_TRANSLESION_SYNTHESIS_BY_Y_FAMILY_DNA_POLYMERASES_BYPASSES_LESIONS_ON_DNA_TEMPLATE

POLD2 POLE2

1.66e-0339222M26897
PathwayREACTOME_RESOLUTION_OF_ABASIC_SITES_AP_SITES

POLD2 POLE2

1.66e-0339222MM17222
PathwayREACTOME_TRANSLESION_SYNTHESIS_BY_Y_FAMILY_DNA_POLYMERASES_BYPASSES_LESIONS_ON_DNA_TEMPLATE

POLD2 POLE2

1.66e-0339222MM14475
PathwayREACTOME_DUAL_INCISION_IN_GG_NER

POLD2 POLE2

1.84e-0341222M27595
PathwayWP_DNA_REPLICATION

POLD2 POLE2

1.93e-0342222M39335
PathwayREACTOME_DUAL_INCISION_IN_GG_NER

POLD2 POLE2

1.93e-0342222MM15306
PathwayKEGG_NUCLEOTIDE_EXCISION_REPAIR

POLD2 POLE2

2.11e-0344222M18937
PathwayWP_NUCLEOTIDE_EXCISION_REPAIR

POLD2 POLE2

2.11e-0344222M39847
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

ITGB6 FBN3

2.11e-0344222M26969
PathwayREACTOME_DNA_DAMAGE_BYPASS

POLD2 POLE2

2.51e-0348222M27698
PathwayREACTOME_DNA_DAMAGE_BYPASS

POLD2 POLE2

2.51e-0348222MM15432
PathwayWP_TGFBETA_SIGNALING_PATHWAY

ITGB6 SMAD6

3.05e-0353222MM15880
PathwayWP_TGFBETA_RECEPTOR_SIGNALING

ITGB6 SMAD6

3.28e-0355222M39351
PathwayWP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS

ITGB6 SMAD6

3.77e-0359222M39886
PathwayREACTOME_HDR_THROUGH_HOMOLOGOUS_RECOMBINATION_HRR

POLD2 POLE2

3.77e-0359222MM15283
Pubmed

Ets1 is required for proper migration and differentiation of the cardiac neural crest.

ADAM19 NOTCH1 SMAD6

8.82e-072230320356956
Pubmed

DNA Polymerases as targets for gene therapy of hepatocellular carcinoma.

POLD2 POLE2

2.16e-06330225924900
Pubmed

Identification of two putative novel folate receptor genes in humans and mouse.

IZUMO1R FOLR1

4.31e-06430211111049
Pubmed

Rare deleterious variants of NOTCH1, GATA4, SMAD6, and ROBO4 are enriched in BAV with early onset complications but not in BAV with heritable thoracic aortic disease.

NOTCH1 SMAD6

4.31e-06430232748548
Pubmed

Spatial and temporal expression of folate-related transporters and metabolic enzymes during mouse placental development.

IZUMO1R FOLR1

2.01e-05830222365888
Pubmed

DNA polymerase δ and ζ switch by sharing accessory subunits of DNA polymerase δ.

POLD2 POLE2

2.01e-05830222465957
Pubmed

Spatiotemporal Decline of BMP Signaling Activity in Neural Progenitors Mediates Fate Transition and Safeguards Neurogenesis.

GSX1 SKOR2

2.58e-05930232187534
Pubmed

N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation.

MARS2 PPARGC1B POGZ ZNF785

3.56e-0521730434048709
Pubmed

Polε Instability Drives Replication Stress, Abnormal Development, and Tumorigenesis.

POLD2 POLE2

5.58e-051330229754823
Pubmed

Zfp423/ZNF423 regulates cell cycle progression, the mode of cell division and the DNA-damage response in Purkinje neuron progenitors.

GSX1 SKOR2

6.50e-051430228893945
Pubmed

Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways.

MUC5B NOTCH1

6.50e-051430222797898
Pubmed

Ascl1 and Gsh1/2 control inhibitory and excitatory cell fate in spinal sensory interneurons.

GSX1 NOTCH1

7.50e-051530216715081
Pubmed

Which DNA polymerases are used for DNA-repair in eukaryotes?

POLD2 POLE2

8.57e-05163029111189
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

POGZ ADAM19 FAM53C ZNF785 DCAF5 SPRYD7 TSPAN7

8.92e-05128530735914814
Pubmed

FOG-2 attenuates endothelial-to-mesenchymal transformation in the endocardial cushions of the developing heart.

NOTCH1 SMAD6

9.70e-051730217274974
Pubmed

Sequential Ligand-Dependent Notch Signaling Activation Regulates Valve Primordium Formation and Morphogenesis.

NOTCH1 SMAD6

1.22e-041930227056911
Pubmed

Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: implications for regulation of BMP signalling.

LAMA5 SMAD6

1.35e-042030222911573
Pubmed

Canonical notch signaling functions as a commitment switch in the epidermal lineage.

ITGB6 NOTCH1

1.50e-042130217079689
Pubmed

Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning.

NOTCH1 SMAD6

1.80e-042330216314491
Pubmed

Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis.

ITGB6 NOTCH1

1.80e-042330219897741
Pubmed

Bmp2 and Notch cooperate to pattern the embryonic endocardium.

NOTCH1 SMAD6

2.31e-042630229853617
Pubmed

Modulation of the notch signaling by Mash1 and Dlx1/2 regulates sequential specification and differentiation of progenitor cell types in the subcortical telencephalon.

GSX1 NOTCH1

2.31e-042630212397111
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

ELAPOR2 COL22A1 DCAF5 LETM1 SKOR2

2.84e-0468930536543142
Pubmed

Mutation of LRP1 in cardiac neural crest cells causes congenital heart defects by perturbing outflow lengthening.

FZD7 NOTCH1

3.29e-043130232546759
Pubmed

ΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation.

LAMA5 NOTCH1

3.29e-043130222274697
Pubmed

β-Catenin regulates endocardial cushion growth by suppressing p21.

NOTCH1 SMAD6

4.20e-043530237385754
Pubmed

Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.

FZD7 GSX1

5.78e-044130218951430
Pubmed

Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry.

MUC5B FCGBP

5.78e-044130216740002
Pubmed

Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.

MUC5B NOTCH1

5.78e-044130222675208
Pubmed

Brg1 plays an essential role in development and homeostasis of the duodenum through regulation of Notch signaling.

FZD7 NOTCH1

8.59e-045030227510977
GeneFamilyDNA polymerases

POLD2 POLE2

3.85e-0423232535
CoexpressionAtlaslung

ELAPOR2 FOLR1 ITGB6 FBN3 SMAD6

3.03e-06182275lung
ToppCell21-Trachea-Epithelial-Submucosal_gland|Trachea / Age, Tissue, Lineage and Cell class

FZD7 MUC5B FOLR1 FBN3

5.99e-061783043e406e38eea0d38dc25edecf703c4c89ec6a28e0
ToppCellfacs-Trachea-24m-Epithelial-glandular_epithelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA5 ELAPOR2 FOLR1 ITGB6

6.83e-0618430461caaa31975e05c9a6512079c791fed5a9e2d39f
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LAMA5 ITGB6 FBN3 SPRYD7

6.83e-0618430429c95b814a0b1ad8734ed68b77df29c08594e5ec
ToppCellfacs-Trachea-24m-Epithelial-glandular_epithelial-lung_secretory_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA5 ELAPOR2 FOLR1 ITGB6

6.83e-0618430403da0f0f89f1ca5a3ccca1e22972f3129464e68e
ToppCellfacs-Trachea-24m-Epithelial-glandular_epithelial-lung_secretory_cell-mucous|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA5 ELAPOR2 FOLR1 ITGB6

6.83e-061843049ed2a65a4ca0ebbbb89ace61027522f93369843d
ToppCellfacs-Trachea-nan-24m-Epithelial-mucus_secreting_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA5 ELAPOR2 FOLR1 ITGB6

6.98e-06185304e502ec54971f518d0cf1b619b745607a8ab5ddf3
ToppCell(7)_Epithelial-I_(AT1)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

LAMA5 FOLR1 ITGB6 FBN3

8.76e-06196304150554fa06868d29b0608189862eef6505ba757f
ToppCellTracheal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Duct|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC5B FCGBP FOLR1 FBN3

9.30e-06199304ef1a0c278c23614fd6a3218a9733abe6ecd6f686
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_vascular|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

LAMA5 PPARGC1B SMAD6 TSPAN7

9.49e-062003046567683f8f534310fecb44a6721909183fdc15ca
ToppCellBiopsy_Control_(H.)-Epithelial-AT1|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

LAMA5 FOLR1 ITGB6 SPRYD7

9.49e-062003043a9633f5913f12b6865fc777c84f3f3ba795a78d
ToppCellCerebellum-Macroglia-ASTROCYTE-Gja1-Bergmann_Glia_(Slc1a3)|Cerebellum / BrainAtlas - Mouse McCarroll V32

GSX1 COL22A1 POLE2

2.83e-0588303a49319bc97188550e08248973e10c626124c3917
ToppCellCerebellum-Macroglia-ASTROCYTE-Gja1-Bergmann_Glia_(Slc1a3)--|Cerebellum / BrainAtlas - Mouse McCarroll V32

GSX1 COL22A1 POLE2

2.83e-05883032075743c7c0b6d74e80464a6bc776206d744d502
ToppCellCerebellum-Macroglia-ASTROCYTE-Gja1-Bergmann_Glia_(Slc1a3)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

GSX1 COL22A1 POLE2

2.83e-058830314b11249a2b3fa327622897fe74630c2697ea47e
ToppCellE18.5-samps-Epithelial-Alveolar_epithelial-AT1|E18.5-samps / Age Group, Lineage, Cell class and subclass

FCGBP FOLR1 ITGB6

9.04e-05130303eb16a8f8f62add5fdd29c78d4608b6d1a06767f1
ToppCellPND07-28-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D|PND07-28-samps / Age Group, Lineage, Cell class and subclass

NOTCH1 SMAD6 TSPAN7

1.13e-04140303b9aeb7dda7f377b580dd8a44912f300721437387
ToppCellSerous|World / shred by cell class for turbinate

MUC5B FCGBP FOLR1

1.38e-041503036a326662d58b0f17d6efa8cc28571f4cbbf57c2d
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B FCGBP FOLR1

1.52e-0415530362b59cb32b12bd55b19e98786a866d788fc9e4bf
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KLHL32 ITGB6 SPRYD7

1.58e-041573039665a1375cfd8e9b8781c852686591226c0e0d9a
ToppCellTCGA-Mesothelium-Primary_Tumor-Mesothelioma-Biphasic-6|TCGA-Mesothelium / Sample_Type by Project: Shred V9

TGFB1I1 ADAM19 POLE2

1.64e-0415930385501c636cd04f15ba1be24df1ba7ac909633ce8
ToppCellNS-critical-LOC-Myeloid-Basophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TGFB1I1 FZD7 TSPAN7

1.67e-041603038a4746463ca1976f7d6de803496c851249ced797
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGB6 POLD2 SPRYD7

1.70e-041613031e17a993126e1f2a25ee7dfbb95a74ccb2a26791
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FZD7 FBN3 TSPAN7

1.83e-04165303a6c6de17fec678ad0cac3138dde3a14cc39ffd26
ToppCellwk_20-22-Epithelial-Airway_epithelial_progenitor|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

LAMA5 FOLR1 FBN3

1.86e-04166303fcd0bd70b553789092249806ace324b77bd10481
ToppCellwk_20-22-Epithelial-Airway_epithelial_progenitor-epi-stalk_late|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

LAMA5 FOLR1 FBN3

1.86e-04166303b60954e5625743657d0fd9264b738b46e72fd8a6
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B FCGBP FOLR1

1.86e-041663039e98e6070055bfc780becee52d77830e06b6d854
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B FCGBP FOLR1

1.89e-0416730331633899aae852873a4887e72c621474b0a51a33
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.1.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B FCGBP FOLR1

1.89e-041673038fede587572d465cb63f7828141a574185bbb819
ToppCellASK440-Immune-B_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

TGFB1I1 KLHL32 TSPAN7

1.93e-04168303127559d1a083c68cda9fce143afcc3eec168df17
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|390C / Donor, Lineage, Cell class and subclass (all cells)

ADAM19 ZNF785 POLE2

1.96e-04169303cfc9ff103d13a2d5eacc457e800f53fdd29f7738
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B FCGBP FOLR1

1.96e-04169303db73dae011ff3749b3706e50ab46d03b775dd6bb
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B FCGBP FOLR1

1.96e-0416930397b7047b87ce0052d8580565c9b44fd2aa6f0d5c
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B FCGBP FOLR1

1.96e-041693031a684471dbda42e1470e5a889648666e14f25982
ToppCellNS-critical-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MUC5B FCGBP FOLR1

1.96e-04169303aec97583b23112060437b619cb429dc32f29285f
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B FCGBP FOLR1

2.07e-041723035401ac7739f95fb8681cfb4747ab6e447a3c2ae8
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B FCGBP FOLR1

2.07e-04172303b3da7f488d191214d7bb74fbac189fe8c29ee6cd
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B FCGBP FOLR1

2.07e-0417230363a91974b12c3f7f0c6bf66c30088d7fc07f5cea
ToppCell356C-Myeloid-Monocyte-CD16+_Monocyte|Monocyte / Donor, Lineage, Cell class and subclass (all cells)

TGFB1I1 MARS2 POLD2

2.07e-041723039dca1542145d88559527db7e0f6ad150df59ca2d
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

LAMA5 MUC5B FOLR1

2.07e-041723030be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NOTCH1 SMAD6 TSPAN7

2.07e-04172303c84cab89c97d647b8a256fd08e33d9102810febd
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B FCGBP FOLR1

2.07e-0417230374dd4a7acb2cf857fed20219e4d7dc1adfbaa398
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)|368C / Donor, Lineage, Cell class and subclass (all cells)

LAMA5 SMAD6 TSPAN7

2.10e-0417330322200fe74e33e2beae0eed289ca8476bbc0b1b2d
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)-|368C / Donor, Lineage, Cell class and subclass (all cells)

LAMA5 SMAD6 TSPAN7

2.10e-04173303ec88e871b49331fca59bc610a8ae58e2d5e76bc1
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B FCGBP FOLR1

2.10e-04173303e8afef5ae68983eb8d6515b43952636a47e9d3d4
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FCGBP KLHL32 FOLR1

2.10e-04173303a809be2630d2b91b53b82b5e2bb99e05524597c1
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B FCGBP FOLR1

2.10e-04173303e4d9a9a781acc531bc81c3fcee24d637e805c8e1
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B FCGBP FOLR1

2.10e-041733033aa1d28d4814798a772808ed29e1dbbdf92abd03
ToppCell367C-Epithelial_cells-Epithelial-I_(AT1)-|367C / Donor, Lineage, Cell class and subclass (all cells)

LAMA5 FOLR1 ITGB6

2.14e-04174303edf839d79ac58921f4e788f3b2cb2ae0d6af4b9e
ToppCelltumor_Lymph_Node_/_Brain-B_lymphocytes-Undetermined|B_lymphocytes / Location, Cell class and cell subclass

TGFB1I1 ELAPOR2 FBN3

2.14e-04174303390bd41ef114464f3db3e0cac4e67fe7571b4c23
ToppCell367C-Epithelial_cells-Epithelial-I_(AT1)|367C / Donor, Lineage, Cell class and subclass (all cells)

LAMA5 FOLR1 ITGB6

2.14e-0417430365539f69100db0b7d90b1b39ee15ab8281f86461
ToppCell356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|356C / Donor, Lineage, Cell class and subclass (all cells)

MUC5B FCGBP FOLR1

2.17e-041753034bfae78ac3a2cb9404382aae96d291504a9cfa14
ToppCell356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|356C / Donor, Lineage, Cell class and subclass (all cells)

MUC5B FCGBP FOLR1

2.17e-04175303af9c5104c86231cfdb93a0f7d7032379efaa009e
ToppCelldroplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAQR8 ELAPOR2 TSPAN7

2.21e-041763033494ffa8555e6edf4b1250e10434bae9b73ec845
ToppCelldroplet-Liver-Npc-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAQR8 ELAPOR2 TSPAN7

2.21e-04176303d43f6b7828b98e1dab7b726a5f99499d65a7db80
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ADAM19 ZNF785 POLE2

2.21e-04176303437cfc5e06416bb0fc76d1f9dc106f74e279e880
ToppCellfacs-Lung-EPCAM-18m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA5 SMAD6 TSPAN7

2.25e-041773032433924dcb085ebbe2545d476ebd7ee68e6092fb
ToppCell(5)_Glands_mucous|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

MUC5B FCGBP FOLR1

2.29e-04178303f0f19b0d78f2cc5df4d4c321a953a6e447d5114a
ToppCellControl-Epithelial_alveolar-AT_1-AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGB6 POLD2 SPRYD7

2.29e-041783031817bc520f3d23da8c0fa09bba50ae703a820cb1
ToppCell3'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA5 FOLR1 SMAD6

2.29e-04178303c30d3390fc4a7856f50ba8ff6694c0333165ddde
ToppCell15-Trachea-Epithelial-Goblet-like_secretory|Trachea / Age, Tissue, Lineage and Cell class

MUC5B FCGBP FOLR1

2.29e-04178303f0557920b9b3e7c4f39938d1b524aa58711af4d2
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_2|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

TGFB1I1 MUC5B GSX1

2.32e-04179303d95367d689732ab2653e8d70d8d8e5eb15ae6eef
ToppCellcellseq-Epithelial-Epithelial_Glandular-Mucous|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC5B FCGBP FOLR1

2.32e-041793039caa7903950c806921b1036103ad0d332a441253
ToppCellcellseq-Epithelial-Epithelial_Glandular-Mucous-Mucous|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC5B FCGBP FOLR1

2.32e-04179303dc4d1b3f63df2c657fea51da011488ee724ee1bf
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FOLR1 FBN3 TSPAN7

2.32e-0417930327ad6a609fe1f7532b142d0147bccf918704a6dd
ToppCell368C-Endothelial_cells-Endothelial-E|368C / Donor, Lineage, Cell class and subclass (all cells)

LAMA5 SMAD6 TSPAN7

2.36e-041803038ab16a0b9053bffc07b569a4f9e71749f56dde7e
ToppCell(5)_Epithelial_cells-(5)_Glands_mucous|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

MUC5B FCGBP FOLR1

2.36e-04180303a4118adaf4b09e2ca01b662ed60e7bbf32a24d58
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_mucus_secreting_cell-SMG_mucous-SMG_mucous_L.0.6.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B FCGBP FOLR1

2.36e-041803038af51245ac1269f318268f574cfaddb0b8c80a53
ToppCell368C-Endothelial_cells-Endothelial-E-|368C / Donor, Lineage, Cell class and subclass (all cells)

LAMA5 SMAD6 TSPAN7

2.36e-04180303394cd465b88429b70eebb2957480dffcbc51cfe7
ToppCellfacs-Heart-RA-24m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOTCH1 SMAD6 TSPAN7

2.36e-04180303174c643e046646e3b305dd7e5b120d2c9a46690f
ToppCellAT1_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

LAMA5 FOLR1 SPRYD7

2.36e-04180303ff4728782c3ec814ba071cc22b7894abdd9da837
ToppCellCOVID-19-Endothelial_cells-Endothelial_cells_(other)|COVID-19 / group, cell type (main and fine annotations)

LAMA5 SMAD6 TSPAN7

2.40e-0418130326eb4ee57a70dbf54e096b73129fda9dfda1f6ec
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Proximal_secretory_1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

MUC5B FCGBP FOLR1

2.40e-04181303bab282cb0d9fc049f6fb094cf8b1fba104f4ea17
ToppCellCOPD-Epithelial-ATI|World / Disease state, Lineage and Cell class

LAMA5 FOLR1 ITGB6

2.44e-04182303e95d946a43b1579af199900bb0e3eacbb9d65300
ToppCelldroplet-Kidney-nan-3m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB1I1 SMAD6 TSPAN7

2.44e-04182303f4a5f1c3a04c0566eb96607dab7a0d9a5ebc3fd1
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Late_airway_progenitor|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

LAMA5 FOLR1 FBN3

2.48e-041833030cea883a8a79fc58abcb26b08bf5db9d3d60f7d4
ToppCellIPF-Epithelial-ATI|World / Disease state, Lineage and Cell class

LAMA5 FOLR1 ITGB6

2.48e-0418330331fef35ecf30162662f24d335d8f0cceacc07039
ToppCellIPF-Epithelial-ATI|IPF / Disease state, Lineage and Cell class

LAMA5 FOLR1 ITGB6

2.48e-04183303c0a3541c45bd0c587603521f392f42dd86c3c35b
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

ELAPOR2 FOLR1 ITGB6

2.52e-041843030ba243cbf69b4fe6ae100a7f0314317bec38026c
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)-|343B / Donor, Lineage, Cell class and subclass (all cells)

LAMA5 FBN3 SPRYD7

2.52e-04184303bde4eaabd3e9bdaed23867d23a919b9d84b52d4b
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

ELAPOR2 FOLR1 ITGB6

2.52e-041843032a8338e94937686a148b5433515700ca0f674058
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)|343B / Donor, Lineage, Cell class and subclass (all cells)

LAMA5 FBN3 SPRYD7

2.52e-04184303cb15d6bae52c5ec251c2235859dc7e65f630ae23
ToppCellMS-matDC|MS / Condition, Cell_class and T cell subcluster

FZD7 FOLR1 SMAD6

2.56e-0418530346bd897349598d85e718e25f9a045d2247723c61
ToppCellMS-matDC-|MS / Condition, Cell_class and T cell subcluster

FZD7 FOLR1 SMAD6

2.56e-041853039fbe70d3a7b106fb31e13b7f95029785f28ca6f4
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B FCGBP FOLR1

2.56e-041853035dee5645240637e135677732a35fd416b37367d4
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA5 MUC5B FCGBP

2.60e-0418630337b93ebd64ebbd08193a746e5bc9b350c2570733
ToppCell(5)_Epithelial_cells-(5)_Glands_duct|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

MUC5B FCGBP FOLR1

2.60e-04186303219b1aeca17503244fabbb780bca58f22c7c0f27
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOTCH1 SMAD6 TSPAN7

2.60e-0418630360830822d3de3147816693404fd03392e04c2b8e
ToppCellEpithelial-alveolar_epithelial_cell_type_1|World / Lineage, Cell type, age group and donor

LAMA5 ITGB6 FBN3

2.60e-0418630309d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCell21-Trachea-Epithelial-Goblet-like_secretory|Trachea / Age, Tissue, Lineage and Cell class

MUC5B FCGBP FOLR1

2.60e-04186303f8cddad28896f0edf10a8645fa49a011b22b120d
ToppCelldroplet-Lung-nan-21m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB1I1 SMAD6 TSPAN7

2.60e-041863035d0cd07b6b51e8ce9e1da949f757dc4575ec5752
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B FCGBP FOLR1

2.60e-0418630355fe25f4d0f2bc0fd4802a0a375169f2c41472fc
ToppCellCOPD-Epithelial-ATI|COPD / Disease state, Lineage and Cell class

LAMA5 FOLR1 ITGB6

2.60e-04186303df0977f6f48a2d4e11b59971f098b01204242f0f
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOTCH1 SMAD6 TSPAN7

2.60e-0418630337860daeecd6d412bd3797f30496a56da667fbd1
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOTCH1 SMAD6 TSPAN7

2.60e-04186303baebeffdd426ce767190ddefc857cc78e6a58d36
ToppCell(5)_Glands_duct|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

MUC5B FCGBP FOLR1

2.60e-04186303ad8d5010e5095508f4995e0c6c016a44e8ffb8dd
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FZD7 FBN3 TSPAN7

2.64e-041873037b0168bdaa7c6c6b39878aff6a17f0943189a380
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B FCGBP FOLR1

2.64e-0418730371d99a1a95d3692a2891da49d4a243bae6e07fd0
ToppCellSMG-Goblet|World / shred by cell class for bronchial biopsy

MUC5B FCGBP FOLR1

2.64e-041873035178118bdec91495253c88f58fd908cf831de7ef
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TGFB1I1 FZD7 ADAM19

2.64e-04187303387cb27c8a20031cd87381a9e1172f1f62e1488b
ToppCellAT1_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

LAMA5 ITGB6 FBN3

2.64e-04187303f1dda349335e08dbfc8395d373924037f5ad2fd6
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

NOTCH1 SMAD6 TSPAN7

2.68e-04188303366a2d59b9c81d8a7659749f9c07efa46b49a39a
DiseaseAortic valve disorder

NOTCH1 SMAD6

3.00e-063302cv:C1260873
DiseaseAortic Valve Disease 1

NOTCH1 SMAD6

5.99e-064302C3887892
DiseaseAortic valve disorder

NOTCH1 SMAD6

5.99e-064302C1260873
DiseaseBicuspid aortic valve

NOTCH1 SMAD6

9.97e-065302C0149630
DiseaseAortic valve calcification

NOTCH1 SMAD6

2.09e-057302C0428791
DiseaseCongenital Abnormality

FOLR1 NOTCH1

5.46e-0511302C0000768
Diseasefacial asymmetry measurement

FAM53C POLE2

1.69e-0419302EFO_0009751
DiseaseCraniofacial Abnormalities

FOLR1 LETM1 NOTCH1

5.30e-04156303C0376634
Diseasemitochondrial metabolism disease (implicated_via_orthology)

MARS2 LETM1

5.82e-0435302DOID:700 (implicated_via_orthology)
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

NOTCH1 SMAD6

1.33e-0353302C4707243
Diseasepeak expiratory flow

PAQR8 ADAM19 FBN3 SMAD6

1.55e-03498304EFO_0009718
Diseasecholangiocarcinoma (is_marker_for)

MUC5B NOTCH1

1.94e-0364302DOID:4947 (is_marker_for)
Diseasecancer (implicated_via_orthology)

ITGB6 POLD2 NOTCH1

2.51e-03268303DOID:162 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
FCTGKSPHCPTNFYQ

ADAM19

486

Q9H013
YSPAPPTCFILCGNF

POLE2

311

P56282
NTFGSFQCECPPGYH

FBN3

1581

Q75N90
PTGFPSSHFSTPCFC

MUC5B

4931

Q9HC84
VPPGPFFNACISDHC

MUC5B

5306

Q9HC84
CGPNTIDHFFCEIPP

OR13G1

166

Q8NGZ3
LPFEASYICHCPPSF

NOTCH1

156

P46531
CPKGAQCLPFSHYFP

IZUMO1R

166

A6ND01
PFGCCTPIHPVYTSS

LETM1

51

O95202
DPFIFPECPHVYFCG

POLD2

391

P49005
PECPHVYFCGNTPSF

POLD2

396

P49005
PCSSIPYFCLPTFGF

ITGB6

196

P18564
TESFHCPPAQSCYPV

FAM214A

41

Q32MH5
ASFPPFGSQYCHAPL

GSX1

81

Q9H4S2
PHGEPFCLANYPSAF

DCAF5

176

Q96JK2
CAEGFTGFPSCYPTP

LAMA5

461

O15230
GFYNNGSSSCHPCPP

ELAPOR2

401

A8MWY0
FFSCPVPEKYFPGSC

PAQR8

261

Q8TEZ7
QTCKSYAVPCPPGHF

FZD7

506

O75084
PDFCPFQCPAHSHYE

FCGBP

3531

Q9Y6R7
PPGQCDPSQCAYFAS

COL22A1

1601

Q8NFW1
QCAPAHRPYSPPFFS

FAM53C

181

Q9NYF3
VGAACQPFHFYFPTP

FOLR1

171

P15328
CNPYHFSRLCGPESP

SMAD6

261

O43541
CSFEIPDFPNHFPTY

POGZ

756

Q7Z3K3
GVSPTCSDHCPYQSP

PPARGC1B

826

Q86YN6
LDCQFSEFYHTPPPG

SPRYD7

171

Q5W111
YPAFCTTCFPSEPGL

MARS2

421

Q96GW9
CGGLFPHPYTFPAAA

SKOR2

401

Q2VWA4
GAPFCPECYFERFSP

TGFB1I1

271

O43294
TSPYFLEHGIPPSCC

TSPAN7

161

P41732
PHSCPDCGRNFSYPS

ZNF785

171

A8K8V0
GIAACFLPAPYFTCP

KLHL32

591

Q96NJ5