| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | RNA polymerase II cis-regulatory region sequence-specific DNA binding | RARA EGR2 MTF1 MAFA DACH1 TBX10 PBX4 MAFB DBP MED1 KLF4 NEUROG2 FOXC1 EBF4 HOXA1 | 8.23e-06 | 1244 | 65 | 15 | GO:0000978 |
| GeneOntologyMolecularFunction | cis-regulatory region sequence-specific DNA binding | RARA EGR2 MTF1 MAFA DACH1 TBX10 PBX4 MAFB DBP MED1 KLF4 NEUROG2 FOXC1 EBF4 HOXA1 | 1.06e-05 | 1271 | 65 | 15 | GO:0000987 |
| GeneOntologyMolecularFunction | RNA polymerase II transcription regulatory region sequence-specific DNA binding | RARA EGR2 MTF1 MAFA DACH1 ETV3 TBX10 PBX4 MAFB DBP MED1 KLF4 NEUROG2 FOXC1 EBF4 HOXA1 | 1.28e-05 | 1459 | 65 | 16 | GO:0000977 |
| GeneOntologyMolecularFunction | phosphatidylinositol 3-kinase regulator activity | 2.59e-05 | 18 | 65 | 3 | GO:0035014 | |
| GeneOntologyMolecularFunction | DNA-binding transcription factor activity, RNA polymerase II-specific | RARA EGR2 MTF1 MAFA DACH1 ETV3 TBX10 PBX4 MAFB DBP KLF4 NEUROG2 FOXC1 EBF4 HOXA1 | 3.67e-05 | 1412 | 65 | 15 | GO:0000981 |
| GeneOntologyMolecularFunction | structural constituent of nuclear pore | 7.19e-05 | 25 | 65 | 3 | GO:0017056 | |
| GeneOntologyMolecularFunction | DNA-binding transcription activator activity, RNA polymerase II-specific | 7.95e-05 | 560 | 65 | 9 | GO:0001228 | |
| GeneOntologyMolecularFunction | DNA-binding transcription activator activity | 8.62e-05 | 566 | 65 | 9 | GO:0001216 | |
| GeneOntologyMolecularFunction | nuclear localization sequence binding | 9.11e-05 | 27 | 65 | 3 | GO:0008139 | |
| GeneOntologyMolecularFunction | chromatin binding | 1.29e-04 | 739 | 65 | 10 | GO:0003682 | |
| GeneOntologyMolecularFunction | phosphatidylinositol 3-kinase activator activity | 3.70e-04 | 9 | 65 | 2 | GO:0141038 | |
| GeneOntologyMolecularFunction | signal sequence binding | 6.13e-04 | 51 | 65 | 3 | GO:0005048 | |
| GeneOntologyMolecularFunction | transmembrane receptor protein tyrosine kinase adaptor activity | 1.54e-03 | 18 | 65 | 2 | GO:0005068 | |
| GeneOntologyMolecularFunction | peroxisome proliferator activated receptor binding | 2.11e-03 | 21 | 65 | 2 | GO:0042975 | |
| GeneOntologyMolecularFunction | chromatin DNA binding | 2.15e-03 | 167 | 65 | 4 | GO:0031490 | |
| GeneOntologyMolecularFunction | RNA polymerase II-specific DNA-binding transcription factor binding | 2.34e-03 | 417 | 65 | 6 | GO:0061629 | |
| GeneOntologyMolecularFunction | promoter-specific chromatin binding | 2.51e-03 | 83 | 65 | 3 | GO:1990841 | |
| GeneOntologyMolecularFunction | DNA-binding transcription factor binding | 2.78e-03 | 582 | 65 | 7 | GO:0140297 | |
| GeneOntologyMolecularFunction | transcription factor binding | 2.98e-03 | 753 | 65 | 8 | GO:0008134 | |
| GeneOntologyMolecularFunction | histone acetyltransferase binding | 4.00e-03 | 29 | 65 | 2 | GO:0035035 | |
| GeneOntologyMolecularFunction | insulin receptor binding | 4.28e-03 | 30 | 65 | 2 | GO:0005158 | |
| GeneOntologyBiologicalProcess | rhombomere 5 development | 1.25e-07 | 4 | 66 | 3 | GO:0021571 | |
| GeneOntologyBiologicalProcess | positive regulation of transcription by RNA polymerase II | RARA EGR2 MTF1 MAFA MLLT6 MAFB AKIRIN2 ASXL2 DBP MED1 TAF6 KLF4 NEUROG2 TOX2 FOXC1 EBF4 HOXA1 | 1.18e-06 | 1390 | 66 | 17 | GO:0045944 |
| GeneOntologyBiologicalProcess | rhombomere development | 2.59e-06 | 9 | 66 | 3 | GO:0021546 | |
| GeneOntologyBiologicalProcess | abducens nerve development | 1.01e-05 | 2 | 66 | 2 | GO:0021560 | |
| GeneOntologyBiologicalProcess | abducens nerve formation | 1.01e-05 | 2 | 66 | 2 | GO:0021599 | |
| GeneOntologyBiologicalProcess | abducens nerve morphogenesis | 1.01e-05 | 2 | 66 | 2 | GO:0021598 | |
| GeneOntologyBiologicalProcess | central nervous system development | RARA EGR2 MTF1 PBX4 MAFB AKIRIN2 IRS2 LOXL3 ULK1 MED1 NEUROG2 TNFRSF21 FOXC1 HOXA1 | 2.06e-05 | 1197 | 66 | 14 | GO:0007417 |
| GeneOntologyBiologicalProcess | nuclear pore organization | 2.47e-05 | 18 | 66 | 3 | GO:0006999 | |
| GeneOntologyBiologicalProcess | nuclear transport | 2.68e-05 | 378 | 66 | 8 | GO:0051169 | |
| GeneOntologyBiologicalProcess | nucleocytoplasmic transport | 2.68e-05 | 378 | 66 | 8 | GO:0006913 | |
| GeneOntologyBiologicalProcess | brain segmentation | 3.02e-05 | 3 | 66 | 2 | GO:0035284 | |
| GeneOntologyBiologicalProcess | protein import into nucleus | 3.75e-05 | 195 | 66 | 6 | GO:0006606 | |
| GeneOntologyBiologicalProcess | response to peptide | RARA SYNJ1 ETV3 IRAK1 OTOP1 IRS1 IRS2 ULK1 MED1 KLF4 TNFRSF21 ZFP36 FOXC1 | 3.84e-05 | 1100 | 66 | 13 | GO:1901652 |
| GeneOntologyBiologicalProcess | import into nucleus | 4.44e-05 | 201 | 66 | 6 | GO:0051170 | |
| GeneOntologyBiologicalProcess | rhombomere 3 development | 6.03e-05 | 4 | 66 | 2 | GO:0021569 | |
| GeneOntologyBiologicalProcess | brain development | RARA EGR2 PBX4 MAFB AKIRIN2 IRS2 ULK1 MED1 NEUROG2 FOXC1 HOXA1 | 8.09e-05 | 859 | 66 | 11 | GO:0007420 |
| GeneOntologyBiologicalProcess | regulation of cell-cell adhesion | 9.17e-05 | 580 | 66 | 9 | GO:0022407 | |
| GeneOntologyBiologicalProcess | central nervous system segmentation | 1.00e-04 | 5 | 66 | 2 | GO:0035283 | |
| GeneOntologyBiologicalProcess | mRNA transport | 1.01e-04 | 145 | 66 | 5 | GO:0051028 | |
| GeneOntologyBiologicalProcess | negative regulation of DNA-templated transcription | RARA CBX6 TRO DACH1 ETV3 IRAK1 MAFB AKIRIN2 ASXL2 LOXL3 MED1 KLF4 ZFP36 FOXC1 | 1.12e-04 | 1399 | 66 | 14 | GO:0045892 |
| GeneOntologyBiologicalProcess | negative regulation of transcription by RNA polymerase II | RARA CBX6 TRO DACH1 ETV3 MAFB AKIRIN2 ASXL2 MED1 KLF4 ZFP36 FOXC1 | 1.13e-04 | 1053 | 66 | 12 | GO:0000122 |
| GeneOntologyBiologicalProcess | negative regulation of RNA biosynthetic process | RARA CBX6 TRO DACH1 ETV3 IRAK1 MAFB AKIRIN2 ASXL2 LOXL3 MED1 KLF4 ZFP36 FOXC1 | 1.25e-04 | 1413 | 66 | 14 | GO:1902679 |
| GeneOntologyBiologicalProcess | cranial nerve morphogenesis | 1.45e-04 | 32 | 66 | 3 | GO:0021602 | |
| GeneOntologyBiologicalProcess | response to cytokine | RARA SYNJ1 ETV3 IRAK1 OTOP1 IRS1 ULK1 MED1 KLF4 TNFRSF21 ZFP36 FOXC1 | 1.47e-04 | 1083 | 66 | 12 | GO:0034097 |
| GeneOntologyBiologicalProcess | head development | RARA EGR2 PBX4 MAFB AKIRIN2 IRS2 ULK1 MED1 NEUROG2 FOXC1 HOXA1 | 1.47e-04 | 919 | 66 | 11 | GO:0060322 |
| GeneOntologyBiologicalProcess | protein localization to nucleus | 1.55e-04 | 362 | 66 | 7 | GO:0034504 | |
| GeneOntologyBiologicalProcess | RNA transport | 2.44e-04 | 175 | 66 | 5 | GO:0050658 | |
| GeneOntologyBiologicalProcess | nucleic acid transport | 2.44e-04 | 175 | 66 | 5 | GO:0050657 | |
| GeneOntologyBiologicalProcess | establishment of RNA localization | 2.64e-04 | 178 | 66 | 5 | GO:0051236 | |
| GeneOntologyBiologicalProcess | regulation of keratinocyte differentiation | 2.84e-04 | 40 | 66 | 3 | GO:0045616 | |
| GeneOntologyBiologicalProcess | epidermal cell differentiation | 2.94e-04 | 284 | 66 | 6 | GO:0009913 | |
| GeneOntologyBiologicalProcess | fat cell differentiation | 3.35e-04 | 291 | 66 | 6 | GO:0045444 | |
| GeneOntologyBiologicalProcess | keratinocyte differentiation | 3.48e-04 | 189 | 66 | 5 | GO:0030216 | |
| GeneOntologyBiologicalProcess | gland development | 3.95e-04 | 558 | 66 | 8 | GO:0048732 | |
| GeneOntologyBiologicalProcess | embryonic organ development | 4.09e-04 | 561 | 66 | 8 | GO:0048568 | |
| GeneOntologyBiologicalProcess | regulation of hematopoietic progenitor cell differentiation | 4.31e-04 | 46 | 66 | 3 | GO:1901532 | |
| GeneOntologyBiologicalProcess | cellular response to granulocyte macrophage colony-stimulating factor stimulus | 4.46e-04 | 10 | 66 | 2 | GO:0097011 | |
| GeneOntologyBiologicalProcess | facial nerve structural organization | 4.46e-04 | 10 | 66 | 2 | GO:0021612 | |
| GeneOntologyBiologicalProcess | hematopoietic stem cell differentiation | 4.59e-04 | 47 | 66 | 3 | GO:0060218 | |
| GeneOntologyBiologicalProcess | regulation of response to cytokine stimulus | 5.05e-04 | 205 | 66 | 5 | GO:0060759 | |
| GeneOntologyBiologicalProcess | sensory organ development | 5.05e-04 | 730 | 66 | 9 | GO:0007423 | |
| GeneOntologyBiologicalProcess | cellular response to epidermal growth factor stimulus | 5.19e-04 | 49 | 66 | 3 | GO:0071364 | |
| GeneOntologyBiologicalProcess | regulation of glycogen metabolic process | 5.19e-04 | 49 | 66 | 3 | GO:0070873 | |
| GeneOntologyBiologicalProcess | hindbrain development | 5.39e-04 | 208 | 66 | 5 | GO:0030902 | |
| GeneOntologyBiologicalProcess | response to granulocyte macrophage colony-stimulating factor | 5.44e-04 | 11 | 66 | 2 | GO:0097012 | |
| GeneOntologyBiologicalProcess | cranial nerve formation | 5.44e-04 | 11 | 66 | 2 | GO:0021603 | |
| GeneOntologyBiologicalProcess | negative regulation of erythrocyte differentiation | 5.44e-04 | 11 | 66 | 2 | GO:0045647 | |
| GeneOntologyBiologicalProcess | regulation of leukocyte cell-cell adhesion | 5.54e-04 | 447 | 66 | 7 | GO:1903037 | |
| GeneOntologyBiologicalProcess | mRNA transcription by RNA polymerase II | 6.18e-04 | 52 | 66 | 3 | GO:0042789 | |
| GeneOntologyBiologicalProcess | facial nerve morphogenesis | 6.52e-04 | 12 | 66 | 2 | GO:0021610 | |
| GeneOntologyBiologicalProcess | facial nerve development | 6.52e-04 | 12 | 66 | 2 | GO:0021561 | |
| GeneOntologyBiologicalProcess | RNA localization | 6.53e-04 | 217 | 66 | 5 | GO:0006403 | |
| GeneOntologyBiologicalProcess | regulation of cell development | RARA SYNJ1 EGR2 SASH3 NEURL1 MAFB ASXL2 LOXL3 ULK1 MED1 ZFP36 | 6.56e-04 | 1095 | 66 | 11 | GO:0060284 |
| GeneOntologyBiologicalProcess | response to epidermal growth factor | 6.91e-04 | 54 | 66 | 3 | GO:0070849 | |
| GeneOntologyBiologicalProcess | positive regulation of fatty acid beta-oxidation | 7.69e-04 | 13 | 66 | 2 | GO:0032000 | |
| GeneOntologyBiologicalProcess | cranial nerve structural organization | 7.69e-04 | 13 | 66 | 2 | GO:0021604 | |
| GeneOntologyBiologicalProcess | mRNA transcription | 8.09e-04 | 57 | 66 | 3 | GO:0009299 | |
| GeneOntologyBiologicalProcess | response to retinoic acid | 8.26e-04 | 131 | 66 | 4 | GO:0032526 | |
| GeneOntologyBiologicalProcess | regulation of polysaccharide metabolic process | 8.51e-04 | 58 | 66 | 3 | GO:0032881 | |
| GeneOntologyBiologicalProcess | leukocyte cell-cell adhesion | 9.06e-04 | 486 | 66 | 7 | GO:0007159 | |
| GeneOntologyBiologicalProcess | regulation of erythrocyte differentiation | 9.40e-04 | 60 | 66 | 3 | GO:0045646 | |
| GeneOntologyBiologicalProcess | cellular response to cytokine stimulus | 9.49e-04 | 967 | 66 | 10 | GO:0071345 | |
| GeneOntologyBiologicalProcess | cellular response to peptide | 1.03e-03 | 15 | 66 | 2 | GO:1901653 | |
| GeneOntologyBiologicalProcess | regulation of response to type II interferon | 1.03e-03 | 15 | 66 | 2 | GO:0060330 | |
| GeneOntologyBiologicalProcess | regulation of type II interferon-mediated signaling pathway | 1.03e-03 | 15 | 66 | 2 | GO:0060334 | |
| GeneOntologyBiologicalProcess | regulation of epidermal cell differentiation | 1.08e-03 | 63 | 66 | 3 | GO:0045604 | |
| GeneOntologyBiologicalProcess | nucleobase-containing compound transport | 1.21e-03 | 249 | 66 | 5 | GO:0015931 | |
| GeneOntologyBiologicalProcess | skin development | 1.22e-03 | 373 | 66 | 6 | GO:0043588 | |
| GeneOntologyBiologicalProcess | regulation of myelination | 1.30e-03 | 67 | 66 | 3 | GO:0031641 | |
| GeneOntologyBiologicalProcess | cranial nerve development | 1.30e-03 | 67 | 66 | 3 | GO:0021545 | |
| GeneOntologyBiologicalProcess | positive regulation of glycogen biosynthetic process | 1.49e-03 | 18 | 66 | 2 | GO:0045725 | |
| GeneOntologyBiologicalProcess | regulation of hematopoietic stem cell differentiation | 1.49e-03 | 18 | 66 | 2 | GO:1902036 | |
| GeneOntologyBiologicalProcess | regulation of epidermis development | 1.53e-03 | 71 | 66 | 3 | GO:0045682 | |
| GeneOntologyBiologicalProcess | cellular response to retinoic acid | 1.66e-03 | 73 | 66 | 3 | GO:0071300 | |
| GeneOntologyBiologicalProcess | regulation of CD4-positive, alpha-beta T cell differentiation | 1.66e-03 | 73 | 66 | 3 | GO:0043370 | |
| GeneOntologyBiologicalProcess | regulation of hemopoiesis | 1.66e-03 | 540 | 66 | 7 | GO:1903706 | |
| GeneOntologyBiologicalProcess | preganglionic parasympathetic fiber development | 1.66e-03 | 19 | 66 | 2 | GO:0021783 | |
| GeneOntologyBiologicalProcess | positive regulation of keratinocyte differentiation | 1.66e-03 | 19 | 66 | 2 | GO:0045618 | |
| GeneOntologyBiologicalProcess | mammary gland development | 1.81e-03 | 162 | 66 | 4 | GO:0030879 | |
| GeneOntologyBiologicalProcess | regulation of B cell activation | 1.85e-03 | 163 | 66 | 4 | GO:0050864 | |
| GeneOntologyBiologicalProcess | embryonic morphogenesis | 1.92e-03 | 713 | 66 | 8 | GO:0048598 | |
| GeneOntologyBiologicalProcess | anatomical structure arrangement | 2.04e-03 | 21 | 66 | 2 | GO:0048532 | |
| GeneOntologyBiologicalProcess | cell-cell adhesion | 2.12e-03 | 1077 | 66 | 10 | GO:0098609 | |
| GeneOntologyBiologicalProcess | regulation of B cell proliferation | 2.16e-03 | 80 | 66 | 3 | GO:0030888 | |
| GeneOntologyCellularComponent | chromatin | RARA EGR2 CBX6 MAFA ETV3 TBX10 PBX4 MAFB AKIRIN2 DBP MED1 TAF6 KLF4 NEUROG2 FOXC1 EBF4 HOXA1 | 2.32e-06 | 1480 | 66 | 17 | GO:0000785 |
| GeneOntologyCellularComponent | nuclear protein-containing complex | RARA POM121 CBX6 ETV3 NUP43 MAFB POLR2M ASXL2 DBP MED1 MED13L TAF6 POM121C POM121B | 8.23e-05 | 1377 | 66 | 14 | GO:0140513 |
| GeneOntologyCellularComponent | transcription regulator complex | 1.02e-04 | 596 | 66 | 9 | GO:0005667 | |
| GeneOntologyCellularComponent | nuclear pore | 2.94e-04 | 101 | 66 | 4 | GO:0005643 | |
| MousePheno | neonatal lethality | CDSN AMER1 RARA SYNJ1 EGR2 KIF26B SCNN1A DACH1 TBX10 MAFB LOXL3 KLF4 NEUROG2 FOXC1 HOXA1 | 4.60e-07 | 799 | 57 | 15 | MP:0002058 |
| MousePheno | abnormal rhombomere 5 morphology | 2.22e-06 | 7 | 57 | 3 | MP:0012800 | |
| MousePheno | abnormal cranial ganglia morphology | 6.67e-06 | 175 | 57 | 7 | MP:0001081 | |
| MousePheno | perinatal lethality | CDSN AMER1 RARA SYNJ1 EGR2 KIF26B SCNN1A DACH1 TBX10 MAFB LOXL3 KLF4 NEUROG2 FOXC1 HOXA1 | 3.24e-05 | 1130 | 57 | 15 | MP:0002081 |
| MousePheno | abnormal rhombomere morphology | 4.20e-05 | 17 | 57 | 3 | MP:0000933 | |
| MousePheno | decreased rhombomere 5 size | 4.89e-05 | 3 | 57 | 2 | MP:0012801 | |
| MousePheno | abnormal neuromere morphology | 5.02e-05 | 18 | 57 | 3 | MP:0003208 | |
| MousePheno | abnormal geniculate ganglion morphology | 5.02e-05 | 18 | 57 | 3 | MP:0001082 | |
| MousePheno | abnormal vestibular nerve morphology | 9.75e-05 | 4 | 57 | 2 | MP:0004718 | |
| MousePheno | perinatal lethality, complete penetrance | CDSN AMER1 SYNJ1 SCNN1A DACH1 TBX10 MAFB KLF4 NEUROG2 FOXC1 HOXA1 | 1.19e-04 | 712 | 57 | 11 | MP:0011089 |
| MousePheno | abnormal vestibular ganglion morphology | 1.22e-04 | 24 | 57 | 3 | MP:0002856 | |
| MousePheno | abnormal rhombomere 3 morphology | 2.42e-04 | 6 | 57 | 2 | MP:0012792 | |
| MousePheno | abnormal rhombomere 4 morphology | 2.42e-04 | 6 | 57 | 2 | MP:0012796 | |
| MousePheno | neonatal lethality, complete penetrance | 2.84e-04 | 534 | 57 | 9 | MP:0011087 | |
| MousePheno | abnormal total retina thickness | 2.84e-04 | 223 | 57 | 6 | MP:0011963 | |
| MousePheno | abnormal glossopharyngeal ganglion morphology | 2.93e-04 | 32 | 57 | 3 | MP:0001096 | |
| MousePheno | abnormal vestibular labyrinth morphology | 3.12e-04 | 80 | 57 | 4 | MP:0004427 | |
| MousePheno | abnormal facial nerve morphology | 3.22e-04 | 33 | 57 | 3 | MP:0001071 | |
| MousePheno | abnormal hyoid bone morphology | 4.17e-04 | 36 | 57 | 3 | MP:0003056 | |
| MousePheno | lethality during fetal growth through weaning, complete penetrance | CDSN AMER1 SYNJ1 EGR2 MTF1 SCNN1A DACH1 TBX10 MAFB LOXL3 KLF4 NEUROG2 FOXC1 HOXA1 | 4.45e-04 | 1269 | 57 | 14 | MP:0011111 |
| MousePheno | absent endolymphatic duct | 4.50e-04 | 8 | 57 | 2 | MP:0000041 | |
| MousePheno | abnormal hindbrain development | 5.35e-04 | 164 | 57 | 5 | MP:0006108 | |
| MousePheno | abnormal kidney development | 5.54e-04 | 93 | 57 | 4 | MP:0000527 | |
| Domain | Maf_N | 6.27e-05 | 4 | 61 | 2 | PF08383 | |
| Domain | Maf_TF_N | 6.27e-05 | 4 | 61 | 2 | IPR013592 | |
| Domain | Transciption_factor_Maf_fam | 2.18e-04 | 7 | 61 | 2 | IPR024874 | |
| Domain | PTBI | 5.66e-04 | 11 | 61 | 2 | SM00310 | |
| Domain | BRLZ | 6.54e-04 | 52 | 61 | 3 | SM00338 | |
| Domain | IRS_PTB | 6.78e-04 | 12 | 61 | 2 | PS51064 | |
| Domain | BZIP | 6.91e-04 | 53 | 61 | 3 | PS50217 | |
| Domain | BZIP_BASIC | 6.91e-04 | 53 | 61 | 3 | PS00036 | |
| Domain | bZIP | 7.30e-04 | 54 | 61 | 3 | IPR004827 | |
| Domain | bZIP_Maf | 8.00e-04 | 13 | 61 | 2 | IPR004826 | |
| Domain | bZIP_Maf | 8.00e-04 | 13 | 61 | 2 | PF03131 | |
| Domain | IRS_PTB | 9.31e-04 | 14 | 61 | 2 | IPR002404 | |
| Domain | IRS | 9.31e-04 | 14 | 61 | 2 | PF02174 | |
| Domain | - | 1.22e-03 | 16 | 61 | 2 | 1.10.880.10 | |
| Domain | TNFR_c6 | 2.32e-03 | 22 | 61 | 2 | PF00020 | |
| Domain | TNFR | 3.24e-03 | 26 | 61 | 2 | SM00208 | |
| Domain | TNFR_NGFR_1 | 4.02e-03 | 29 | 61 | 2 | PS00652 | |
| Domain | TNFR_NGFR_2 | 4.02e-03 | 29 | 61 | 2 | PS50050 | |
| Domain | Death | 5.19e-03 | 33 | 61 | 2 | PF00531 | |
| Domain | TNFR/NGFR_Cys_rich_reg | 5.19e-03 | 33 | 61 | 2 | IPR001368 | |
| Domain | TF_DNA-bd | 6.49e-03 | 37 | 61 | 2 | IPR008917 | |
| Domain | Death_domain | 6.84e-03 | 38 | 61 | 2 | IPR000488 | |
| Pathway | REACTOME_POSTMITOTIC_NUCLEAR_PORE_COMPLEX_NPC_REFORMATION | 1.41e-06 | 24 | 50 | 4 | MM15658 | |
| Pathway | REACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY | 1.16e-05 | 40 | 50 | 4 | MM14945 | |
| Pathway | REACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS | 1.29e-05 | 41 | 50 | 4 | MM15200 | |
| Pathway | REACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS | 1.42e-05 | 42 | 50 | 4 | MM15039 | |
| Pathway | REACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA | 1.56e-05 | 43 | 50 | 4 | MM14609 | |
| Pathway | REACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS | 2.23e-05 | 47 | 50 | 4 | MM14939 | |
| Pathway | REACTOME_GENE_SILENCING_BY_RNA | 2.64e-05 | 49 | 50 | 4 | MM14837 | |
| Pathway | REACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS | 2.86e-05 | 50 | 50 | 4 | MM14610 | |
| Pathway | REACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS | 3.09e-05 | 51 | 50 | 4 | MM15151 | |
| Pathway | REACTOME_NUCLEAR_ENVELOPE_BREAKDOWN | 4.18e-05 | 55 | 50 | 4 | MM14917 | |
| Pathway | REACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS | 5.16e-05 | 58 | 50 | 4 | MM15149 | |
| Pathway | REACTOME_SNRNP_ASSEMBLY | 5.16e-05 | 58 | 50 | 4 | MM14736 | |
| Pathway | WP_ROLES_OF_CERAMIDES_IN_DEVELOPMENT_OF_INSULIN_RESISTANCE | 7.07e-05 | 23 | 50 | 3 | M45533 | |
| Pathway | REACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS | 8.08e-05 | 65 | 50 | 4 | MM15147 | |
| Pathway | REACTOME_NUCLEAR_ENVELOPE_NE_REASSEMBLY | 9.65e-05 | 68 | 50 | 4 | MM14921 | |
| Pathway | REACTOME_IRS_ACTIVATION | 1.22e-04 | 5 | 50 | 2 | M27707 | |
| Pathway | REACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE | 1.27e-04 | 73 | 50 | 4 | MM14948 | |
| Pathway | WP_WHITE_FAT_CELL_DIFFERENTIATION | 1.94e-04 | 32 | 50 | 3 | M39333 | |
| Pathway | REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN | 1.94e-04 | 32 | 50 | 3 | M29579 | |
| Pathway | REACTOME_GLUCOSE_METABOLISM | 2.00e-04 | 82 | 50 | 4 | MM15394 | |
| Pathway | REACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE | 2.00e-04 | 82 | 50 | 4 | M27250 | |
| Pathway | REACTOME_EXPORT_OF_VIRAL_RIBONUCLEOPROTEINS_FROM_NUCLEUS | 2.13e-04 | 33 | 50 | 3 | M27016 | |
| Pathway | WP_WHITE_FAT_CELL_DIFFERENTIATION | 2.13e-04 | 33 | 50 | 3 | MM15869 | |
| Pathway | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | 2.19e-04 | 84 | 50 | 4 | M1008 | |
| Pathway | REACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS | 2.19e-04 | 84 | 50 | 4 | MM14929 | |
| Pathway | REACTOME_NUCLEAR_IMPORT_OF_REV_PROTEIN | 2.33e-04 | 34 | 50 | 3 | M27041 | |
| Pathway | REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM | 2.40e-04 | 86 | 50 | 4 | MM15413 | |
| Pathway | REACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS | 2.54e-04 | 35 | 50 | 3 | M27320 | |
| Pathway | REACTOME_SOS_MEDIATED_SIGNALLING | 2.56e-04 | 7 | 50 | 2 | M19489 | |
| Pathway | REACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY | 2.76e-04 | 36 | 50 | 3 | M27245 | |
| Pathway | REACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA | 2.76e-04 | 36 | 50 | 3 | M26974 | |
| Pathway | REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS | 3.00e-04 | 37 | 50 | 3 | M1029 | |
| Pathway | REACTOME_INTERACTIONS_OF_REV_WITH_HOST_CELLULAR_PROTEINS | 3.00e-04 | 37 | 50 | 3 | M27038 | |
| Pathway | REACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS | 3.11e-04 | 92 | 50 | 4 | MM14951 | |
| Pathway | REACTOME_SUMOYLATION | 3.20e-04 | 169 | 50 | 5 | MM14919 | |
| Pathway | REACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS | 3.51e-04 | 39 | 50 | 3 | M27238 | |
| Pathway | REACTOME_NS1_MEDIATED_EFFECTS_ON_HOST_PATHWAYS | 4.07e-04 | 41 | 50 | 3 | M29574 | |
| Pathway | REACTOME_PI3K_AKT_ACTIVATION | 4.37e-04 | 9 | 50 | 2 | M714 | |
| Pathway | KEGG_ALDOSTERONE_REGULATED_SODIUM_REABSORPTION | 4.37e-04 | 42 | 50 | 3 | M16473 | |
| Pathway | REACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS | 4.44e-04 | 101 | 50 | 4 | M27253 | |
| Pathway | REACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS | 4.69e-04 | 43 | 50 | 3 | M26975 | |
| Pathway | REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS | 5.02e-04 | 44 | 50 | 3 | M109 | |
| Pathway | REACTOME_SIGNAL_ATTENUATION | 5.45e-04 | 10 | 50 | 2 | M14236 | |
| Pathway | REACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS | 5.72e-04 | 46 | 50 | 3 | M27397 | |
| Pathway | KEGG_TYPE_II_DIABETES_MELLITUS | 6.10e-04 | 47 | 50 | 3 | M19708 | |
| Pathway | REACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS | 6.10e-04 | 47 | 50 | 3 | M27395 | |
| Pathway | REACTOME_ADIPOGENESIS | 6.13e-04 | 110 | 50 | 4 | M48259 | |
| Pathway | REACTOME_SIGNALING_BY_LEPTIN | 6.64e-04 | 11 | 50 | 2 | M27195 | |
| Pathway | REACTOME_MITOTIC_PROPHASE | 7.01e-04 | 114 | 50 | 4 | MM15361 | |
| Pathway | REACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA | 7.98e-04 | 118 | 50 | 4 | M27316 | |
| Pathway | REACTOME_NUCLEAR_ENVELOPE_BREAKDOWN | 8.68e-04 | 53 | 50 | 3 | M27212 | |
| Pathway | REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS | 9.04e-04 | 122 | 50 | 4 | M29689 | |
| Pathway | REACTOME_SNRNP_ASSEMBLY | 9.17e-04 | 54 | 50 | 3 | M29594 | |
| Pathway | REACTOME_SARS_COV_2_ACTIVATES_MODULATES_INNATE_AND_ADAPTIVE_IMMUNE_RESPONSES | 1.02e-03 | 126 | 50 | 4 | M45009 | |
| Pathway | WP_ADIPOGENESIS | 1.18e-03 | 131 | 50 | 4 | M39505 | |
| Pathway | REACTOME_TRNA_PROCESSING_IN_THE_NUCLEUS | 1.19e-03 | 59 | 50 | 3 | M27606 | |
| Pathway | WP_ADIPOGENESIS_GENES | 1.39e-03 | 137 | 50 | 4 | MM15970 | |
| Pathway | PID_IL4_2PATHWAY | 1.50e-03 | 64 | 50 | 3 | M28 | |
| Pathway | WP_LEPTININSULIN_SIGNALING_OVERLAP | 1.62e-03 | 17 | 50 | 2 | M39517 | |
| Pathway | KEGG_MEDICUS_REFERENCE_IL1_IL1R_P38_SIGNALING_PATHWAY | 1.62e-03 | 17 | 50 | 2 | M47470 | |
| Pathway | REACTOME_HIV_LIFE_CYCLE | 1.89e-03 | 149 | 50 | 4 | M4076 | |
| Pathway | REACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS | 2.03e-03 | 71 | 50 | 3 | M27394 | |
| Pathway | WP_LEPTININSULIN_SIGNALING_OVERLAP | 2.25e-03 | 20 | 50 | 2 | MM15867 | |
| Pathway | REACTOME_ISG15_ANTIVIRAL_MECHANISM | 2.28e-03 | 74 | 50 | 3 | M48006 | |
| Pathway | WP_FOXA2_PATHWAY | 2.48e-03 | 21 | 50 | 2 | M42579 | |
| Pathway | REACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS | 2.55e-03 | 77 | 50 | 3 | M27226 | |
| Pathway | WP_TRANSCRIPTION_FACTOR_REGULATION_IN_ADIPOGENESIS | 2.72e-03 | 22 | 50 | 2 | M39414 | |
| Pathway | WP_TYPE_II_DIABETES_MELLITUS | 2.72e-03 | 22 | 50 | 2 | M39658 | |
| Pathway | REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING | 3.24e-03 | 24 | 50 | 2 | M519 | |
| Pathway | REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM | 3.27e-03 | 84 | 50 | 3 | M725 | |
| Pathway | REACTOME_GLUCOSE_METABOLISM | 3.38e-03 | 85 | 50 | 3 | M1870 | |
| Pathway | WP_EPO_RECEPTOR_SIGNALING | 3.79e-03 | 26 | 50 | 2 | M39687 | |
| Pathway | PID_RXR_VDR_PATHWAY | 3.79e-03 | 26 | 50 | 2 | M162 | |
| Pathway | KEGG_MEDICUS_REFERENCE_DEUBIQUITINATION_OF_H2AK119 | 3.79e-03 | 26 | 50 | 2 | M47923 | |
| Pathway | WP_EPO_RECEPTOR_SIGNALING | 3.79e-03 | 26 | 50 | 2 | MM15896 | |
| Pathway | REACTOME_POSTMITOTIC_NUCLEAR_PORE_COMPLEX_NPC_REFORMATION | 4.09e-03 | 27 | 50 | 2 | M29807 | |
| Pathway | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES | 4.09e-03 | 27 | 50 | 2 | M1718 | |
| Pathway | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_GENE_EXPRESSION | 4.09e-03 | 27 | 50 | 2 | M26943 | |
| Pathway | REACTOME_SUMOYLATION | 4.46e-03 | 189 | 50 | 4 | M27214 | |
| Pathway | PID_IGF1_PATHWAY | 4.71e-03 | 29 | 50 | 2 | M125 | |
| Pathway | KEGG_MEDICUS_REFERENCE_NUCLEAR_EXPORT_OF_MRNA | 5.03e-03 | 30 | 50 | 2 | M47752 | |
| Pathway | REACTOME_SLC_TRANSPORTER_DISORDERS | 5.19e-03 | 99 | 50 | 3 | M27474 | |
| Pathway | WP_OREXIN_RECEPTOR_PATHWAY | 5.44e-03 | 200 | 50 | 4 | M48048 | |
| Pathway | REACTOME_SARS_COV_2_HOST_INTERACTIONS | 5.83e-03 | 204 | 50 | 4 | M45011 | |
| Pubmed | A census of human transcription factors: function, expression and evolution. | RARA EGR2 MTF1 MAFA ETV3 TBX10 PBX4 MAFB DBP KLF4 NEUROG2 TOX2 CRAMP1 FOXC1 EBF4 HOXA1 | 1.03e-11 | 908 | 66 | 16 | 19274049 |
| Pubmed | POM121 inhibits the macrophage inflammatory response by impacting NF-κB P65 nuclear accumulation. | 6.53e-09 | 3 | 66 | 3 | 30802453 | |
| Pubmed | 6.53e-09 | 3 | 66 | 3 | 35507432 | ||
| Pubmed | 1.59e-08 | 15 | 66 | 4 | 11532923 | ||
| Pubmed | A dual-activity topoisomerase complex regulates mRNA translation and turnover. | SYNJ1 IRAK1 MLLT6 IRS1 IRS2 ULK1 MED13L KLF4 MAST2 POM121C PLEKHG5 TNFRSF21 C2CD2 CRAMP1 | 1.63e-08 | 1105 | 66 | 14 | 35748872 |
| Pubmed | Two distinct human POM121 genes: requirement for the formation of nuclear pore complexes. | 2.61e-08 | 4 | 66 | 3 | 17900573 | |
| Pubmed | An atlas of combinatorial transcriptional regulation in mouse and man. | RARA MTF1 CBX6 DACH1 PBX4 MAFB DBP MED1 NEUROG2 ZFP36 EBF4 HOXA1 | 8.66e-08 | 877 | 66 | 12 | 20211142 |
| Pubmed | Roles of retinoic acid receptors in early embryonic morphogenesis and hindbrain patterning. | 1.30e-07 | 6 | 66 | 3 | 11493525 | |
| Pubmed | 3.63e-07 | 8 | 66 | 3 | 15367676 | ||
| Pubmed | Hoxa1 and Hoxb1 synergize in patterning the hindbrain, cranial nerves and second pharyngeal arch. | 3.63e-07 | 8 | 66 | 3 | 9463359 | |
| Pubmed | Hox and Pbx factors control retinoic acid synthesis during hindbrain segmentation. | 7.76e-07 | 10 | 66 | 3 | 21497760 | |
| Pubmed | Development of the vertebrate ear: insights from knockouts and mutants. | 7.76e-07 | 10 | 66 | 3 | 10354604 | |
| Pubmed | Peering through the pore: nuclear pore complex structure, assembly, and function. | 8.32e-07 | 38 | 66 | 4 | 12791264 | |
| Pubmed | Impact of cytosine methylation on DNA binding specificities of human transcription factors. | 8.80e-07 | 544 | 66 | 9 | 28473536 | |
| Pubmed | 1.42e-06 | 12 | 66 | 3 | 10529420 | ||
| Pubmed | 1.42e-06 | 12 | 66 | 3 | 10529422 | ||
| Pubmed | Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function. | 1.42e-06 | 12 | 66 | 3 | 28798046 | |
| Pubmed | 2.55e-06 | 50 | 66 | 4 | 27026076 | ||
| Pubmed | 2.92e-06 | 15 | 66 | 3 | 14697343 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 11886449 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 17222321 | ||
| Pubmed | Insulin receptor substrate-1/2 mediates IL-4-induced migration of human airway epithelial cells. | 3.55e-06 | 2 | 66 | 2 | 19447894 | |
| Pubmed | Divergent roles for IRS-1 and IRS-2 in breast cancer metastasis. | 3.55e-06 | 2 | 66 | 2 | 17361103 | |
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 9495343 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 37550630 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 33839150 | ||
| Pubmed | Roles of Insulin Receptor Substrates (IRS) in renal function and renal hemodynamics. | 3.55e-06 | 2 | 66 | 2 | 33270683 | |
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 15975995 | ||
| Pubmed | Systematic modeling for the insulin signaling network mediated by IRS(1) and IRS(2). | 3.55e-06 | 2 | 66 | 2 | 24703981 | |
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 27708333 | ||
| Pubmed | Impairment of bone healing by insulin receptor substrate-1 deficiency. | 3.55e-06 | 2 | 66 | 2 | 14736890 | |
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 17928362 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 21356519 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 22994406 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 15069074 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 19596788 | ||
| Pubmed | Insulin receptor substrate (IRS)-2, not IRS-1, protects human neuroblastoma cells against apoptosis. | 3.55e-06 | 2 | 66 | 2 | 19259821 | |
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 12810606 | ||
| Pubmed | Large Maf transcription factor family is a major regulator of fast type IIb myofiber determination. | 3.55e-06 | 2 | 66 | 2 | 36952339 | |
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 18396140 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 12055235 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 11522686 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 34449768 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 20074531 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 7675087 | ||
| Pubmed | Selective insulin resistance with differential expressions of IRS-1 and IRS-2 in human NAFLD livers. | 3.55e-06 | 2 | 66 | 2 | 29717275 | |
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 11546755 | ||
| Pubmed | Increased insulin resistance in obese children who have both 972 IRS-1 and 1057 IRS-2 polymorphisms. | 3.55e-06 | 2 | 66 | 2 | 12475767 | |
| Pubmed | Variations in insulin secretion in carriers of gene variants in IRS-1 and -2. | 3.55e-06 | 2 | 66 | 2 | 11872698 | |
| Pubmed | Essential role of insulin receptor substrate 1 (IRS-1) and IRS-2 in adipocyte differentiation. | 3.55e-06 | 2 | 66 | 2 | 11259600 | |
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 12213887 | ||
| Pubmed | Association of IRS-1 and IRS-2 genes polymorphisms with polycystic ovary syndrome: a meta-analysis. | 3.55e-06 | 2 | 66 | 2 | 22523112 | |
| Pubmed | Generation and characterization of MafA-Kusabira Orange mice. | 3.55e-06 | 2 | 66 | 2 | 25273397 | |
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 27247938 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 17641282 | ||
| Pubmed | Night-Shift Work Duration and Risk of Colorectal Cancer According to IRS1 and IRS2 Expression. | 3.55e-06 | 2 | 66 | 2 | 31666286 | |
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 34537327 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 25310961 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 32764399 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 15849359 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 26991655 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 15572028 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 37173295 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 25002528 | ||
| Pubmed | Targeting type 2 diabetes: lessons from a knockout model of insulin receptor substrate 2. | 3.55e-06 | 2 | 66 | 2 | 24977713 | |
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 28003360 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 11078455 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 21325637 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 17374994 | ||
| Pubmed | Irs1 and Irs2 signaling is essential for hepatic glucose homeostasis and systemic growth. | 3.55e-06 | 2 | 66 | 2 | 16374520 | |
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 20210696 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 12746333 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 22205343 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 17222824 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 31393907 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 24159000 | ||
| Pubmed | Inhibition of TNF-α improves the bladder dysfunction that is associated with type 2 diabetes. | 3.55e-06 | 2 | 66 | 2 | 22688336 | |
| Pubmed | Dysregulation of insulin receptor substrate 2 in beta cells and brain causes obesity and diabetes. | 3.55e-06 | 2 | 66 | 2 | 15467829 | |
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 18515495 | ||
| Pubmed | Polymorphism analysis of the Gly972Arg IRS-1 and Gly1057Asp IRS-2 genes in obese pregnant women. | 3.55e-06 | 2 | 66 | 2 | 32540195 | |
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 18590687 | ||
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 18590692 | ||
| Pubmed | MafB Maintains β-Cell Identity under MafA-Deficient Conditions. | 3.55e-06 | 2 | 66 | 2 | 35862726 | |
| Pubmed | 3.55e-06 | 2 | 66 | 2 | 17030631 | ||
| Pubmed | Insulin receptor substrate 2 is essential for maturation and survival of photoreceptor cells. | 3.55e-06 | 2 | 66 | 2 | 15689562 | |
| Pubmed | 5.22e-06 | 18 | 66 | 3 | 21930923 | ||
| Pubmed | 8.47e-06 | 21 | 66 | 3 | 39055950 | ||
| Pubmed | 1.06e-05 | 3 | 66 | 2 | 11018022 | ||
| Pubmed | Inhibition of PTP1B restores IRS1-mediated hepatic insulin signaling in IRS2-deficient mice. | 1.06e-05 | 3 | 66 | 2 | 20028942 | |
| Pubmed | MafA is critical for maintenance of the mature beta cell phenotype in mice. | 1.06e-05 | 3 | 66 | 2 | 25500951 | |
| Pubmed | 1.06e-05 | 3 | 66 | 2 | 27098445 | ||
| Pubmed | 1.06e-05 | 3 | 66 | 2 | 19531492 | ||
| Pubmed | Tamoxifen reduces fat mass by boosting reactive oxygen species. | 1.06e-05 | 3 | 66 | 2 | 25569103 | |
| Pubmed | 1.06e-05 | 3 | 66 | 2 | 10417963 | ||
| Pubmed | 1.06e-05 | 3 | 66 | 2 | 19542202 | ||
| Pubmed | 1.06e-05 | 3 | 66 | 2 | 8621590 | ||
| Pubmed | 1.06e-05 | 3 | 66 | 2 | 19273608 | ||
| Pubmed | Insulin signaling and glucose homeostasis in mice lacking protein tyrosine phosphatase alpha. | 1.06e-05 | 3 | 66 | 2 | 14733908 | |
| Pubmed | The type I interferon receptor mediates tyrosine phosphorylation of insulin receptor substrate 2. | 1.06e-05 | 3 | 66 | 2 | 8550573 | |
| Pubmed | 1.06e-05 | 3 | 66 | 2 | 17898946 | ||
| Interaction | PAX6 interactions | 2.54e-06 | 366 | 65 | 9 | int:PAX6 | |
| Interaction | NCOA6 interactions | 7.28e-06 | 145 | 65 | 6 | int:NCOA6 | |
| Cytoband | 10q25.1 | 2.73e-04 | 17 | 66 | 2 | 10q25.1 | |
| Cytoband | 9q31 | 2.73e-04 | 17 | 66 | 2 | 9q31 | |
| Cytoband | 7q11.23 | 3.80e-04 | 97 | 66 | 3 | 7q11.23 | |
| GeneFamily | CD molecules|Tumor necrosis factor receptor superfamily|Death inducing signaling complex | 1.96e-03 | 29 | 41 | 2 | 782 | |
| GeneFamily | Nucleoporins | 2.38e-03 | 32 | 41 | 2 | 1051 | |
| GeneFamily | Cyclins|Mediator complex | 2.53e-03 | 33 | 41 | 2 | 1061 | |
| GeneFamily | Basic leucine zipper proteins | 5.52e-03 | 49 | 41 | 2 | 506 | |
| Coexpression | HARALAMBIEVA_PBMC_FLUARIX_AGE_50_74YO_CORR_WITH_28D_MEM_B_CELL_RESPONSE_AT_3DY_POSITIVE | POM121 CBX6 ETV3 IRAK1 POLR2M IRS2 MED13L KLF4 TNFRSF21 FAM53C ZFP36 | 1.64e-09 | 368 | 65 | 11 | M41100 |
| Coexpression | NAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_7DY_DN | 5.50e-06 | 276 | 65 | 7 | M41128 | |
| Coexpression | HARALAMBIEVA_PBMC_FLUARIX_AGE_50_74YO_CORR_WITH_28D_MEM_B_CELL_RESPONSE_AT_28DY_POSITIVE | RARA CBX6 DACH1 MAFB AKIRIN2 IRS2 LOXL3 ULK1 MED13L KLF4 TNFRSF21 FAM53C ZFP36 | 1.01e-05 | 1250 | 65 | 13 | M41099 |
| Coexpression | HARALAMBIEVA_PBMC_FLUARIX_AGE_50_74YO_CORR_WITH_28D_MEM_B_CELL_RESPONSE_AT_0DY_NEGATIVE | 1.19e-05 | 435 | 65 | 8 | M41115 | |
| Coexpression | GESERICK_TERT_TARGETS_DN | 1.88e-05 | 21 | 65 | 3 | M15891 | |
| Coexpression | GESERICK_TERT_TARGETS_DN | 1.88e-05 | 21 | 65 | 3 | MM1085 | |
| Coexpression | DASU_IL6_SIGNALING_SCAR_UP | 6.23e-05 | 31 | 65 | 3 | M292 | |
| Coexpression | STK33_NOMO_UP | 8.32e-05 | 290 | 65 | 6 | M2855 | |
| Coexpression | SEAVEY_EPITHELIOID_HEMANGIOENDOTHELIOMA | 8.52e-05 | 93 | 65 | 4 | M42516 | |
| Coexpression | GSE2770_UNTREATED_VS_ACT_CD4_TCELL_2H_UP | 1.34e-04 | 198 | 65 | 5 | M6025 | |
| Coexpression | GSE12366_PLASMA_CELL_VS_MEMORY_BCELL_DN | 1.37e-04 | 199 | 65 | 5 | M3177 | |
| Coexpression | GSE43955_1H_VS_60H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN | 1.40e-04 | 200 | 65 | 5 | M9685 | |
| Coexpression | GSE15330_GRANULOCYTE_MONOCYTE_PROGENITOR_VS_PRO_BCELL_DN | 1.40e-04 | 200 | 65 | 5 | M7042 | |
| Coexpression | HALLMARK_ESTROGEN_RESPONSE_EARLY | 1.40e-04 | 200 | 65 | 5 | M5906 | |
| Coexpression | GSE19923_WT_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_DN | 1.40e-04 | 200 | 65 | 5 | M7269 | |
| Coexpression | GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_LPS_STIM_UP | 1.40e-04 | 200 | 65 | 5 | M8642 | |
| Coexpression | GSE12392_CD8A_POS_VS_NEG_SPLEEN_IFNB_KO_DC_DN | 1.40e-04 | 200 | 65 | 5 | M7134 | |
| Coexpression | MARTINEZ_RB1_AND_TP53_TARGETS_DN | 1.99e-04 | 650 | 65 | 8 | MM1042 | |
| Coexpression | ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_DN | 2.05e-04 | 46 | 65 | 3 | MM1256 | |
| Coexpression | MARTINEZ_TP53_TARGETS_DN | 2.19e-04 | 659 | 65 | 8 | MM1040 | |
| CoexpressionAtlas | dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#3_top-relative-expression-ranked_500 | 2.63e-05 | 116 | 64 | 5 | gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k3_500 | |
| ToppCell | Control-B_naive-13|World / disease group and sub_cluster of B and Plasma cells(res = 0.5) | 4.23e-07 | 193 | 66 | 6 | 2c1fce66ad688f2ec0278fc86afaa1bf107bb9f4 | |
| ToppCell | NS-moderate-d_16-33-Epithelial-unknown_epithelial|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined) | 1.87e-06 | 137 | 66 | 5 | 03e124901a0e85b59b6882bbafab568b50907e8b | |
| ToppCell | moderate-Epithelial-unknown_epithelial|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls | 1.94e-06 | 138 | 66 | 5 | afefa8233c67aa744e939156bc538449bf6bd05b | |
| ToppCell | metastatic_Lymph_Node-Myeloid_cells-CD1c+_DCs|metastatic_Lymph_Node / Location, Cell class and cell subclass | 7.50e-06 | 182 | 66 | 5 | 551d301adfb4d5046c5f60f6996450621b04e9b2 | |
| ToppCell | wk_08-11-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung | 9.72e-06 | 192 | 66 | 5 | 7ae3e1ca8bfc078c0e12a1595ecb0e343dab5d2f | |
| ToppCell | 15|World / Age, Tissue, Lineage and Cell class | 9.97e-06 | 193 | 66 | 5 | a8ad0de955494d6f5929dc44ba46627d06d95453 | |
| ToppCell | Control-B_naive-13|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5) | 9.97e-06 | 193 | 66 | 5 | 32e53a6473a682cf14b20a399c3686f658298b93 | |
| ToppCell | 3'-Adult-LargeIntestine-Epithelial-goblet|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 1.02e-05 | 194 | 66 | 5 | 1a188e52f2f0b6eca3e8d4a4671d9beab0fbbb88 | |
| ToppCell | 3'-Adult-LargeIntestine-Epithelial-goblet-BEST2+_Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 1.05e-05 | 195 | 66 | 5 | 3365768101454060b9ea96ef6b426c76c150bc8f | |
| ToppCell | Control|World / Condition, Lineage and Cell class | 1.07e-05 | 196 | 66 | 5 | 2565f567c5274d1689e11600a2cb9e6770b65f74 | |
| ToppCell | LPS_only-Hematopoietic_Myeloid-Dendritic_cells-pDC|LPS_only / Treatment groups by lineage, cell group, cell type | 1.13e-05 | 198 | 66 | 5 | d205dfcfe1f20e1e21bf84759e723d9e6e610a5c | |
| ToppCell | control-Neutrophil|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class | 1.18e-05 | 200 | 66 | 5 | b5d197472799cc61d7497faed91ac2564ae4930a | |
| ToppCell | NS-moderate-d_07-13-Epithelial-unknown_epithelial|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined) | 4.17e-05 | 130 | 66 | 4 | 1491e8975520e99c527a5b5bee64875d124f7bf4 | |
| ToppCell | Children_(3_yrs)-Endothelial-endothelial_cell_of_vein-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor | 7.28e-05 | 150 | 66 | 4 | 4f31867cb85253ff6d22f3b02ef972a42cb41123 | |
| ToppCell | 3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 9.35e-05 | 160 | 66 | 4 | 33050dc646762dc7e9dcc4a12c618e1ba1ce5a4d | |
| ToppCell | droplet-Fat-SCAT-30m-Myeloid-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 9.35e-05 | 160 | 66 | 4 | 61eefe84c8e30d8a3812f5b48d26ed01739aa1ce | |
| ToppCell | facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.05e-04 | 165 | 66 | 4 | 1703d3eb644b3c743ad3c5532b1d29ea010c79c8 | |
| ToppCell | 10x5'-Lung-Myeloid_Dendritic-pDC|Lung / Manually curated celltypes from each tissue | 1.13e-04 | 168 | 66 | 4 | 90f713dae3fcbd6ca801a019e3861c263ff3366b | |
| ToppCell | 10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like|GI_small-bowel / Manually curated celltypes from each tissue | 1.13e-04 | 168 | 66 | 4 | d02eba7ece17edcdd47fd6b784c93910ce61090f | |
| ToppCell | PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k) | 1.15e-04 | 169 | 66 | 4 | a0681317867e31319210a23e56660a53f4529efe | |
| ToppCell | wk_08-11-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung | 1.18e-04 | 170 | 66 | 4 | fefb07a7e308b620f946b9ff2b01e1796446fe38 | |
| ToppCell | 367C-Myeloid-Dendritic-pDC|Dendritic / Donor, Lineage, Cell class and subclass (all cells) | 1.18e-04 | 170 | 66 | 4 | fbb7019c6fba87326702b51f6819ea1af5f3a9b7 | |
| ToppCell | 10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3|GI_small-bowel / Manually curated celltypes from each tissue | 1.18e-04 | 170 | 66 | 4 | 97df5ffb328196c46568975d2d97722bcc753bf5 | |
| ToppCell | 5'-Adult-LargeIntestine-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 1.21e-04 | 171 | 66 | 4 | 48125d825ca2d7ef34564250f5b47d2a579e03c9 | |
| ToppCell | PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k) | 1.21e-04 | 171 | 66 | 4 | 7b0783d25055e5ea5b2fc44ebcb16bfd0adbcf81 | |
| ToppCell | droplet-Marrow-nan-3m-Myeloid-monocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.21e-04 | 171 | 66 | 4 | 992df143d76f9e7fb1997a8996f61e941f0f9d4f | |
| ToppCell | PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k) | 1.24e-04 | 172 | 66 | 4 | ac20766d1fd43eab8c3ff5e7418a6b38bebf0bd5 | |
| ToppCell | PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k) | 1.24e-04 | 172 | 66 | 4 | 3fd1bc4a8ced0bf9e26ca4ce6d83b5b97bbc2556 | |
| ToppCell | critical-Epithelial-unknown_epithelial|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls | 1.26e-04 | 173 | 66 | 4 | 4144b1cdefa8c37b6ac7a6d249fa5292ffb2b8b2 | |
| ToppCell | facs-Brain_Non-Myeloid-Cortex_-18m-Myeloid-microglial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.29e-04 | 174 | 66 | 4 | 8d6df5938cef542f23259ce471eea1a1afbed03c | |
| ToppCell | facs-Brain_Non-Myeloid-Cortex_-18m-Myeloid|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.29e-04 | 174 | 66 | 4 | 2af54c3427aacfa232e2aca6003b4a8ecb8bba66 | |
| ToppCell | facs-Brain_Non-Myeloid-Cortex_-18m-Myeloid-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.29e-04 | 174 | 66 | 4 | eca643b8f5b92aeed5a77c94b4301fd8100f9401 | |
| ToppCell | IIF-Myeloid-pDC|IIF / Disease, Lineage and Cell Type | 1.32e-04 | 175 | 66 | 4 | 35cfb7d0b88678ff5b83ad6e19dbc15a908a3fcc | |
| ToppCell | 356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells) | 1.32e-04 | 175 | 66 | 4 | f3a68aeb79c4935006e17a5ff3445a8ec0e33f5f | |
| ToppCell | droplet-Marrow-nan-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.32e-04 | 175 | 66 | 4 | cf53a15bfb37b6019e7052ffdf594a9ac040900e | |
| ToppCell | normal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells|normal_Lymph_Node / Location, Cell class and cell subclass | 1.32e-04 | 175 | 66 | 4 | 29fbdfe1d3bfcb063be2bced0128a33176c5b78f | |
| ToppCell | Adult-Immune-dendritic_cell-D175|Adult / Lineage, Cell type, age group and donor | 1.35e-04 | 176 | 66 | 4 | 1f0f1f953e6d61119f342de0d980aa1287511dba | |
| ToppCell | renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group | 1.47e-04 | 180 | 66 | 4 | cfc8bfbfd3617aabbb49f9730c29b673ca157e74 | |
| ToppCell | facs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype | 1.47e-04 | 180 | 66 | 4 | e9785ac2806103f725f5a5208495826354ec6e22 | |
| ToppCell | control-Lymphoid-B_cell|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls | 1.50e-04 | 181 | 66 | 4 | e414303bb90e5fe7b667c2acf9a50f8694b90e54 | |
| ToppCell | NS-control-d_0-4-Lymphoid-B_cell|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined) | 1.54e-04 | 182 | 66 | 4 | 4b9b55154a79992112c1c467e8752c3cdbb541d9 | |
| ToppCell | E16.5-samps-Endothelial-Immature_fetal_endothelial-Intermediate_Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass | 1.54e-04 | 182 | 66 | 4 | fec1caf867b1dc87b24504d895ee1a27df78062e | |
| ToppCell | PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k) | 1.57e-04 | 183 | 66 | 4 | 3b123571e10c132227aff65648b4b3c6acb4bd00 | |
| ToppCell | PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Dendritic-plasmacytoid_dendritic_cell|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k) | 1.57e-04 | 183 | 66 | 4 | df6fd0927b6e4cf9a1583969a68096e4bccfbace | |
| ToppCell | PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung | 1.57e-04 | 183 | 66 | 4 | e84539978ab4de42e19186aed00f24bb50cbc21f | |
| ToppCell | 10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group | 1.57e-04 | 183 | 66 | 4 | 62f76907e501bba6e1010b5c447faed5f0ef93a7 | |
| ToppCell | Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types | 1.60e-04 | 184 | 66 | 4 | 2ba98708dfd7f1b2a661578a334684094ff453ad | |
| ToppCell | Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor | 1.63e-04 | 185 | 66 | 4 | 8207f9eff113eed429e961748c6b17d672a13b33 | |
| ToppCell | droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.67e-04 | 186 | 66 | 4 | 16092819e9148dfe64f07c737652b6e533e699f7 | |
| ToppCell | TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9 | 1.67e-04 | 186 | 66 | 4 | 03db813598b67b1e08f759758a1c2023396921fa | |
| ToppCell | LPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 1.70e-04 | 187 | 66 | 4 | f3397dbc23b6c2f24e2c1ba887d8f9aef3ee01a1 | |
| ToppCell | COVID-19-kidney-CD-IC-B|kidney / Disease (COVID-19 only), tissue and cell type | 1.70e-04 | 187 | 66 | 4 | ce05b89860573fe0356102e2998d1ef6d1968034 | |
| ToppCell | PBMC-Mild-Myeloid-pDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 1.77e-04 | 189 | 66 | 4 | 209cae68d78c8f72479b169e27c3ff7e143adece | |
| ToppCell | PBMC-Mild-Myeloid-pDC-pDC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 1.77e-04 | 189 | 66 | 4 | a9ad1fb12304541f909dd0eeac9b9eb28c31fd41 | |
| ToppCell | PBMC-Mild-Myeloid-pDC-pDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 1.77e-04 | 189 | 66 | 4 | 98ca646231fbd5f29827c2dd31ac4503026bad7d | |
| ToppCell | PBMC-Control-Myeloid-pDC-pDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 1.81e-04 | 190 | 66 | 4 | 9a91bf1ea105029e6412d0d9060bca325299ce26 | |
| ToppCell | MS-pDC-|MS / Condition, Cell_class and T cell subcluster | 1.81e-04 | 190 | 66 | 4 | f56ec302d556ace4f7609017a35c311cf43aa8a5 | |
| ToppCell | PBMC-Control-Myeloid-pDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 1.81e-04 | 190 | 66 | 4 | 2c1c079fd411c03bc3f383aa927eea9446716960 | |
| ToppCell | MS-pDC|MS / Condition, Cell_class and T cell subcluster | 1.81e-04 | 190 | 66 | 4 | f41d7ab7d7fbcd73fddb6c3533c6a3e642e3d07f | |
| ToppCell | PBMC-Control-Myeloid-pDC-pDC-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 1.81e-04 | 190 | 66 | 4 | a95aea3aa707fc4574810706341a5f32b3d00209 | |
| ToppCell | COVID-19_Moderate-pDC|World / disease group, cell group and cell class | 1.85e-04 | 191 | 66 | 4 | 93adfbc0b22f6006d6d5ad67a99e33cbe9e1dfe9 | |
| ToppCell | (011)_pDC|World / immune cells in Peripheral Blood (logTPM normalization) | 1.85e-04 | 191 | 66 | 4 | d82ac4f6d9863734e09bf3cb71c1354a49b66b4f | |
| ToppCell | Control-pDC|Control / Disease condition and Cell class | 1.85e-04 | 191 | 66 | 4 | 543e1437a52d04436862dd1c27b4fae95c44fcc8 | |
| ToppCell | COVID-19_Moderate-pDC|COVID-19_Moderate / disease group, cell group and cell class | 1.85e-04 | 191 | 66 | 4 | 9d0ffa65c547e20b4076fd97776d7738cbd453ec | |
| ToppCell | Control-pDC-|Control / Disease condition and Cell class | 1.85e-04 | 191 | 66 | 4 | 1d7b0fae4d114d6db933c18b4eb2066ffa61356d | |
| ToppCell | Healthy-pDC|World / disease group, cell group and cell class | 1.85e-04 | 191 | 66 | 4 | 6e1d825dc33b915b95f13ccd237a552160a4be98 | |
| ToppCell | PBMC-Severe-Myeloid-cDC-cDC-cDC_5|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09) | 1.85e-04 | 191 | 66 | 4 | 92c5a26b90a55831039220341d863cf2940f3c9b | |
| ToppCell | PBMC-Severe-Myeloid-cDC-cDC-cDC_5|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 1.88e-04 | 192 | 66 | 4 | 6184163dbfca882824cb266bb9030d9f79e3acb0 | |
| ToppCell | PBMC-Control-Myeloid-cDC-cDC-cDC_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09) | 1.88e-04 | 192 | 66 | 4 | dfb9101622f7d2f2c392e850cff07becfc8c655e | |
| ToppCell | PBMC-Control-Myeloid-cDC-cDC-cDC_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 1.88e-04 | 192 | 66 | 4 | d39133cf1a20af6f2970188630fc3b27a4cfc9c5 | |
| ToppCell | Healthy-pDC|Healthy / disease group, cell group and cell class | 1.88e-04 | 192 | 66 | 4 | 33d695a28d22b4af111df9591830a33bb7ef7b2d | |
| ToppCell | PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k) | 1.88e-04 | 192 | 66 | 4 | 7bcdbd97fa8c3bfccde426d44979601226913fc3 | |
| ToppCell | PBMC-Control-cDC_5|Control / Compartment, Disease Groups and Clusters | 1.92e-04 | 193 | 66 | 4 | 53ddee444dcfb9fe568e9e8fb64bc8304c262530 | |
| ToppCell | Neuron-Postmitotic-Inhibitory_Neuron-SST-MGE1-4|World / Primary Cells by Cluster | 1.92e-04 | 193 | 66 | 4 | 2eb6e4cff4fe3ce564c1581f6f7df4834895aaa9 | |
| ToppCell | wk_15-18|World / Celltypes from embryonic and fetal-stage human lung | 1.92e-04 | 193 | 66 | 4 | a28ff1e80e3e741739abe869df5fbd41352a1ea0 | |
| ToppCell | 10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group | 1.92e-04 | 193 | 66 | 4 | 26a55e98005163122d277480d1d44dd6910ab42f | |
| ToppCell | PND01|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 1.92e-04 | 193 | 66 | 4 | c291345c11cfcbceacbdc001a5851f67478a2779 | |
| ToppCell | 3'-Child04-06-SmallIntestine-Epithelial-goblet-Goblet_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 1.96e-04 | 194 | 66 | 4 | 49cc5f5de4380302100e8cd937f08abe317ac75e | |
| ToppCell | facs-Brain_Myeloid-Cortex-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.96e-04 | 194 | 66 | 4 | 2224c7c943cfd5c1a329dfcf19d6e5ef8c49d85d | |
| ToppCell | facs-Brain_Myeloid-Cortex-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.96e-04 | 194 | 66 | 4 | 50c5fc349533281a426bc7227a8ea9eca8d11985 | |
| ToppCell | Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group | 1.96e-04 | 194 | 66 | 4 | ce0486ce43748ffe486f08fdddd1f6acbfcc6b0e | |
| ToppCell | 3'-Child04-06-SmallIntestine-Epithelial-goblet|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 1.96e-04 | 194 | 66 | 4 | fb935df966c451e659b8bde281f8aebcb632f6cf | |
| ToppCell | Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group | 1.96e-04 | 194 | 66 | 4 | 5022c85ad3b137dae4b9ff11f9c23bb3bf4c0f5a | |
| ToppCell | COVID_vent-Myeloid-Monocytic-CD16+_Monocyte|COVID_vent / Disease condition, Lineage, Cell class and subclass | 1.96e-04 | 194 | 66 | 4 | b133d3d198360269cc449a75d34c29be377d91e0 | |
| ToppCell | Macrophages-Donor_01|World / lung cells shred on cell class, cell subclass, sample id | 1.96e-04 | 194 | 66 | 4 | 54fda501ce1d041285d04c3c96c15983f454bed4 | |
| ToppCell | Bronchial_Brush-Immune-Dendritic_cells|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X | 1.96e-04 | 194 | 66 | 4 | dbcc00940538efc0f89f074dbe822c50efa5ad8e | |
| ToppCell | facs-Brain_Myeloid-Cortex-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.96e-04 | 194 | 66 | 4 | 1662b110f84584e75150df0ac970e7df82f26e7e | |
| ToppCell | facs-Brain_Myeloid-Cortex-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.96e-04 | 194 | 66 | 4 | b31d6361fa939a92a4a3dc63c209ecd3eb514e6a | |
| ToppCell | 3'-Pediatric_IBD-SmallIntestine-Epithelial-goblet|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 2.00e-04 | 195 | 66 | 4 | c5f33b420c9ac14dc67fea632b8c2bc2442cbf3d | |
| ToppCell | severe-Classical_Monocyte|World / disease stage, cell group and cell class | 2.00e-04 | 195 | 66 | 4 | cf638aac4d57ae0774008920a1a5e9dfd8c73885 | |
| ToppCell | 10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group | 2.00e-04 | 195 | 66 | 4 | 562e4c0e4e81f6303e57b846da71d1667fc35963 | |
| ToppCell | renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group | 2.00e-04 | 195 | 66 | 4 | 42bfdff88da1d07828c0ad65d412fb1752f0cee4 | |
| ToppCell | metastatic_Brain-Myeloid_cells-Microglia/Mac|metastatic_Brain / Location, Cell class and cell subclass | 2.00e-04 | 195 | 66 | 4 | ae48d493ebda5f87781181a3d1d73d8f84fc5e77 | |
| ToppCell | 10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group | 2.00e-04 | 195 | 66 | 4 | fa8ac154e5aebc26463ff84f0ad1038095770bc6 | |
| ToppCell | 3'-Pediatric_IBD-SmallIntestine-Epithelial-goblet-Goblet_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 2.00e-04 | 195 | 66 | 4 | 219c5d0cde7f6082755154f54db221413ec555cb | |
| ToppCell | 3'-Child09-12-SmallIntestine-Epithelial-goblet|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 2.04e-04 | 196 | 66 | 4 | c2d17630f7bfc9e727de55e093c17fddac61b61f | |
| ToppCell | 5'-Adult-LargeIntestine-Epithelial-goblet|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 2.04e-04 | 196 | 66 | 4 | 847b3377f463bfded046eec63cc1b547f3dc33c1 | |
| ToppCell | COVID-19_Severe-Non-classical_Monocyte|COVID-19_Severe / disease group, cell group and cell class | 2.04e-04 | 196 | 66 | 4 | af9e8f5ef9d03862f707e105857309b55595b1b9 | |
| ToppCell | remission-Non-classical_Monocyte|remission / disease stage, cell group and cell class | 2.04e-04 | 196 | 66 | 4 | 049d995986c20ce066bd64fcc2d2f1c2f8899883 | |
| ToppCell | PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Monocytic-Nonclassical_Monocyte|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k) | 2.04e-04 | 196 | 66 | 4 | 29246378ffb1010fe6858da756ae3d13df2306ba | |
| Drug | Parthenolide [20554-84-1]; Up 200; 16.2uM; PC3; HT_HG-U133A | 9.18e-06 | 173 | 64 | 6 | 5105_UP | |
| Drug | Ciclopirox ethanolamine [41621-49-2]; Up 200; 15uM; HL60; HT_HG-U133A | 9.49e-06 | 174 | 64 | 6 | 2456_UP | |
| Drug | retinoic acid; Up 200; 1uM; MCF7; HT_HG-U133A | 1.35e-05 | 185 | 64 | 6 | 6931_UP | |
| Drug | retinoic acid; Up 200; 1uM; MCF7; HG-U133A | 1.61e-05 | 191 | 64 | 6 | 224_UP | |
| Disease | creatinine measurement | PTPN3 KIF26B DACH1 TNFRSF6B PBX4 MAFB ASXL2 MED1 KLF4 MAST2 CRIP3 | 1.03e-05 | 995 | 65 | 11 | EFO_0004518 |
| Disease | amnestic disorder (implicated_via_orthology) | 1.70e-04 | 9 | 65 | 2 | DOID:10914 (implicated_via_orthology) | |
| Disease | serum gamma-glutamyl transferase measurement | 1.70e-04 | 914 | 65 | 9 | EFO_0004532 | |
| Disease | nasopharyngeal neoplasm | 3.50e-04 | 151 | 65 | 4 | EFO_0004252 | |
| Disease | erythritol measurement | 6.36e-04 | 17 | 65 | 2 | EFO_0021171 | |
| Disease | Liver carcinoma | 8.76e-04 | 507 | 65 | 6 | C2239176 | |
| Disease | osteoporosis (biomarker_via_orthology) | 1.07e-03 | 22 | 65 | 2 | DOID:11476 (biomarker_via_orthology) | |
| Disease | type 2 diabetes mellitus (implicated_via_orthology) | 1.63e-03 | 105 | 65 | 3 | DOID:9352 (implicated_via_orthology) | |
| Disease | hematocrit | 1.66e-03 | 1011 | 65 | 8 | EFO_0004348 | |
| Disease | TYPE 2 DIABETES MELLITUS | 1.74e-03 | 28 | 65 | 2 | 125853 | |
| Disease | Type 2 diabetes mellitus | 1.74e-03 | 28 | 65 | 2 | cv:C0011860 | |
| Disease | glucose metabolism disease (implicated_via_orthology) | 1.74e-03 | 28 | 65 | 2 | DOID:4194 (implicated_via_orthology) | |
| Disease | Ovarian Mucinous Adenocarcinoma | 2.13e-03 | 31 | 65 | 2 | C1335167 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| CSTPLSSSLLGPPGT | 571 | P55198 | |
| RSSGSSGCPSPTPQS | 271 | O95503 | |
| SGPASPGTSSAASSP | 121 | Q53H80 | |
| YSPSPGLSPFTSSSC | 276 | P41162 | |
| SSSSGGFSPSPLPQA | 1061 | Q5JTC6 | |
| GSKGPCSPSSSRVPS | 386 | Q15517 | |
| SPCSPPGTGSFSSSS | 421 | Q15517 | |
| SSSSSSSSCGPLPGK | 156 | Q9UI36 | |
| SSSSPQSGCPSPTIP | 136 | Q76L83 | |
| HTGPGSPSYSSAPCT | 121 | Q8NFH3 | |
| SPSGPSPSCLGDSLA | 86 | Q9H714 | |
| PGSCSPSLSPSSNRS | 441 | P10276 | |
| PSASVPAPSTASCSG | 431 | P11161 | |
| SSVSPSSNAPGSCSP | 456 | P26045 | |
| GFTSSPSPFSSSSPE | 456 | O14526 | |
| SSLGTPTPTSPGVCS | 2336 | Q6W4X9 | |
| PSSSGPASAPSTCSF | 136 | O43474 | |
| PSPSPSPGSSSSFSG | 636 | A5PL33 | |
| SSCLGSPSPSTGPEK | 21 | P58215 | |
| QPGFSAGPSSSSSLP | 446 | Q71F56 | |
| PAGSVSSTPLSTPCS | 51 | Q9Y5Q3 | |
| SVPSSPSFCAPSPGT | 61 | Q8NHW3 | |
| TSPYSCTLSPASPAG | 231 | Q9H2A3 | |
| PGSGTSSPSSFTGSP | 71 | Q2KJY2 | |
| SPGSSNVSSPLPCFG | 161 | Q9H019 | |
| SSPCVPSPGSSTSDT | 316 | P49639 | |
| PSSASTFLSPAFPGS | 136 | P51617 | |
| CSPDIGGGPSSSSSS | 671 | P35568 | |
| STTPSPFTFGGSAAP | 1071 | A8CG34 | |
| STTPSPFTFGGSAAP | 676 | A6NF01 | |
| STTPSPFTFGGSAAP | 1091 | Q96HA1 | |
| PSSGSASASGSPSDP | 481 | Q9Y4H2 | |
| SCLSTPSSGSSGPFP | 301 | Q9BYU1 | |
| GSSGPAACSPPSSSA | 21 | Q7RTM1 | |
| PSGPQSFTLTSGSAC | 356 | Q9Y426 | |
| PSSTGGPDSPPSTFC | 121 | Q96B18 | |
| PGSFSSSSLGAPLPS | 86 | Q6EEV4 | |
| CSSASPRGFAPSPGS | 456 | Q9BQW3 | |
| SLSSGSSPPGSLPSA | 266 | Q12948 | |
| SSKTFPPSSAPCSSG | 791 | Q96RY5 | |
| SPGGSSRGSPSVSCS | 16 | Q5TEA3 | |
| TPSPGCTTPLSPSSF | 81 | Q6Q6R5 | |
| SPSTSGLTPTSSCSP | 1631 | Q6P0Q8 | |
| GLTPTSSCSPPSSTS | 1636 | Q6P0Q8 | |
| SPGPGSCGSASPRSS | 151 | Q10586 | |
| PFSSPSPASGGSFSE | 186 | Q6PJP8 | |
| PPPLSASCSPTGGSS | 336 | Q9NYF3 | |
| STGSELCSPSPGSGS | 146 | O75995 | |
| PSPGGSAGASSSTCP | 651 | P37088 | |
| PPSQFSSCPGPASSG | 121 | Q5SV97 | |
| SSNRPFTPPTSTGGS | 1026 | Q15648 | |
| PASSPSPLSGSALCG | 631 | P49848 | |
| CGTLPSFSSSTSPSP | 211 | O75509 | |
| SGLGTSPSSSPRTSP | 1036 | O43426 | |
| APVPGSSSSTLPSSC | 681 | Q14872 | |
| SSGPSSSVFGSLPPA | 266 | O95081 | |
| PCKPSSPGADSSLSS | 281 | Q9UPV0 | |
| LGSPFPSGPCTSSTG | 31 | O75333 | |
| PTPSSCSLPSGSSGS | 221 | O94827 | |
| CSTAAPPTPASSGSA | 61 | Q8N377 | |
| CSPASTPTSPSALGS | 461 | O76050 | |
| GPPSTSACFSGATSP | 1171 | Q12816 | |
| GATSPSFCDGPSTST | 1181 | Q12816 | |
| PGLAGPSLSSSSFSP | 201 | P26651 | |
| DGSCPSPFASPGPSS | 2131 | O00507 | |
| PAVSAASSGCSSPGP | 131 | A0A0U1RQS6 | |
| ASSGCSSPGPSPLAL | 136 | A0A0U1RQS6 | |
| PSGPSGPSTSSTSKS | 276 | Q68CL5 | |
| SGSCSPGPSNPTSSG | 446 | Q96NM4 | |
| SFSPGLSTCSSSQPP | 16 | Q5VSD8 | |
| PVPSYPSSGSGSSSS | 291 | O75385 | |
| QPCPPGTFSASSSSS | 151 | O95407 |