Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

ATG5 TRIM49 FBXW8 HECW2 UBR4 ZFP91 TRIM49C TRIM31 TRIM49D1 HECTD1 DDB2

9.70e-065128411GO:0019787
GeneOntologyMolecularFunctionaminoacyltransferase activity

ATG5 TRIM49 FBXW8 HECW2 UBR4 ZFP91 TRIM49C TRIM31 TRIM49D1 HECTD1 DDB2

1.39e-055328411GO:0016755
GeneOntologyMolecularFunctionacyltransferase activity

ATG5 TRIM49 FBXW8 ACSM3 MBOAT1 HECW2 UBR4 ZFP91 TRIM49C TRIM31 TRIM49D1 HECTD1 DDB2

2.01e-057758413GO:0016746
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

TRIM49 FBXW8 HECW2 UBR4 ZFP91 TRIM49C TRIM31 TRIM49D1 HECTD1 DDB2

2.91e-054738410GO:0004842
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

ATG5 TRIM49 FBXW8 HECW2 UBR4 TRIM49C TRIM31 TRIM49D1 HECTD1

4.47e-05398849GO:0061659
GeneOntologyMolecularFunctionnatural killer cell lectin-like receptor binding

RAET1G ULBP2 RAET1L

4.68e-0517843GO:0046703
GeneOntologyMolecularFunctionubiquitin protein ligase activity

TRIM49 FBXW8 HECW2 UBR4 TRIM49C TRIM31 TRIM49D1 HECTD1

1.71e-04372848GO:0061630
GeneOntologyMolecularFunctionvinculin binding

NRAP ACTN1

1.32e-0313842GO:0017166
GeneOntologyBiologicalProcessprotein modification by small protein conjugation or removal

ATG5 TRIM49 IFIH1 KCTD9 FBXW8 USP11 HECW2 UBR4 ZFP91 TRIM49C TRIM31 TRIM49D1 BCL11A ASB15 PSMD14 HECTD1 DDB2

4.42e-0710098317GO:0070647
GeneOntologyBiologicalProcesspost-translational protein modification

ATG5 TRIM49 IFIH1 KCTD9 FBXW8 USP11 HECW2 UBR4 ZFP91 TRIM49C TRIM31 TRIM49D1 BCL11A ASB15 PSMD14 HECTD1 DDB2

1.05e-0610748317GO:0043687
GeneOntologyBiologicalProcesscellular response to exogenous dsRNA

IFIH1 RAET1G ULBP2 RAET1L

1.69e-0622834GO:0071360
GeneOntologyBiologicalProcessprotein modification by small protein conjugation

ATG5 TRIM49 IFIH1 KCTD9 FBXW8 HECW2 UBR4 ZFP91 TRIM49C TRIM31 TRIM49D1 BCL11A ASB15 HECTD1 DDB2

2.42e-068938315GO:0032446
GeneOntologyBiologicalProcesscellular response to dsRNA

IFIH1 RAET1G ULBP2 RAET1L

4.64e-0628834GO:0071359
GeneOntologyBiologicalProcesssusceptibility to natural killer cell mediated cytotoxicity

RAET1G ULBP2 RAET1L

5.19e-069833GO:0042271
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous antigen

ATG5 RAET1G ULBP2 RAET1L

8.04e-0632834GO:0019883
GeneOntologyBiologicalProcessprotein ubiquitination

ATG5 TRIM49 KCTD9 FBXW8 HECW2 UBR4 ZFP91 TRIM49C TRIM31 TRIM49D1 ASB15 HECTD1 DDB2

2.03e-058118313GO:0016567
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent

RAET1G ULBP2 RAET1L

3.39e-0516833GO:0002486
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway

RAET1G ULBP2 RAET1L

4.10e-0517833GO:0002484
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen via MHC class Ib

RAET1G ULBP2 RAET1L

4.10e-0517833GO:0002476
GeneOntologyBiologicalProcessantigen processing and presentation of peptide antigen via MHC class Ib

RAET1G ULBP2 RAET1L

4.91e-0518833GO:0002428
GeneOntologyBiologicalProcessresponse to exogenous dsRNA

IFIH1 RAET1G ULBP2 RAET1L

7.11e-0555834GO:0043330
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen via MHC class I

RAET1G ULBP2 RAET1L

1.05e-0423833GO:0019885
GeneOntologyBiologicalProcessresponse to dsRNA

IFIH1 RAET1G ULBP2 RAET1L

1.21e-0463834GO:0043331
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen

RAET1G ULBP2 RAET1L

1.36e-0425833GO:0002483
GeneOntologyBiologicalProcessantigen processing and presentation via MHC class Ib

RAET1G ULBP2 RAET1L

1.36e-0425833GO:0002475
GeneOntologyBiologicalProcesspositive regulation of nitric oxide biosynthetic process

RAET1G ULBP2 RAET1L EDN1

1.37e-0465834GO:0045429
GeneOntologyBiologicalProcesspositive regulation of nitric oxide metabolic process

RAET1G ULBP2 RAET1L EDN1

1.54e-0467834GO:1904407
GeneOntologyBiologicalProcesspositive regulation of response to tumor cell

RAET1G ULBP2 RAET1L

1.91e-0428833GO:0002836
GeneOntologyBiologicalProcesspositive regulation of immune response to tumor cell

RAET1G ULBP2 RAET1L

1.91e-0428833GO:0002839
GeneOntologyBiologicalProcessregulation of dendrite development

FBXW8 HECW2 SYNE1 DGKG BCL11A

3.50e-04150835GO:0050773
GeneOntologyBiologicalProcesspositive regulation of natural killer cell activation

RAET1G ULBP2 RAET1L

3.75e-0435833GO:0032816
GeneOntologyBiologicalProcesscilium assembly

ATG5 FBXW8 CFAP91 TCHP SYNE1 CEP290 NUDCD3 BBS9

4.17e-04444838GO:0060271
GeneOntologyBiologicalProcessmaternal process involved in parturition

NODAL EDN1

4.41e-048832GO:0060137
GeneOntologyBiologicalProcesspositive regulation of natural killer cell mediated cytotoxicity

RAET1G ULBP2 RAET1L

5.58e-0440833GO:0045954
GeneOntologyBiologicalProcessantigen processing and presentation of peptide antigen via MHC class I

RAET1G ULBP2 RAET1L

6.00e-0441833GO:0002474
GeneOntologyBiologicalProcessregulation of nitric oxide biosynthetic process

RAET1G ULBP2 RAET1L EDN1

6.36e-0497834GO:0045428
GeneOntologyBiologicalProcesspositive regulation of T cell mediated cytotoxicity

RAET1G ULBP2 RAET1L

6.44e-0442833GO:0001916
GeneOntologyBiologicalProcesspositive regulation of macrophage activation

RAET1G ULBP2 RAET1L

6.44e-0442833GO:0043032
GeneOntologyBiologicalProcesscilium organization

ATG5 FBXW8 CFAP91 TCHP SYNE1 CEP290 NUDCD3 BBS9

6.58e-04476838GO:0044782
GeneOntologyBiologicalProcessregulation of nitric oxide metabolic process

RAET1G ULBP2 RAET1L EDN1

7.13e-04100834GO:0080164
GeneOntologyBiologicalProcesspositive regulation of natural killer cell mediated immunity

RAET1G ULBP2 RAET1L

7.39e-0444833GO:0002717
GeneOntologyCellularComponentrough endoplasmic reticulum lumen

LRPAP1 EDN1

1.58e-045842GO:0048237
DomainSox7/17/18_central

SOX7 SOX18

5.98e-053842IPR033392
DomainSox17_18_mid

SOX7 SOX18

5.98e-053842PF12067
DomainSox_C

SOX7 SOX18

5.98e-053842IPR021934
DomainSOX_C

SOX7 SOX18

5.98e-053842PS51516
DomainMHC_I

RAET1G ULBP2 RAET1L

1.10e-0421843PF00129
DomainMHC_I_a_a1/a2

RAET1G ULBP2 RAET1L

1.10e-0421843IPR001039
Domain-

RAET1G ULBP2 RAET1L

1.66e-04248433.30.500.10
DomainMHC_I-like_Ag-recog

RAET1G ULBP2 RAET1L

1.66e-0424843IPR011161
DomainBBOX

TRIM49 TRIM49C TRIM31 TRIM49D1

2.63e-0469844SM00336
DomainButyrophylin

TRIM49 TRIM49C BTN2A3P TRIM49D1

2.78e-0470844IPR003879
Domain-

TRIM49 TRIM49C TRIM31 TRIM49D1

2.94e-04718444.10.45.10
DomainDUF3398

DOCK8 DOCK7

2.96e-046842PF11878
DomainDOCK_C/D_N

DOCK8 DOCK7

2.96e-046842IPR021816
Domainzf-B_box

TRIM49 TRIM49C TRIM31 TRIM49D1

3.10e-0472844PF00643
DomainZF_BBOX

TRIM49 TRIM49C TRIM31 TRIM49D1

4.64e-0480844PS50119
DomainZnf_B-box

TRIM49 TRIM49C TRIM31 TRIM49D1

4.87e-0481844IPR000315
DomainSPRY

TRIM49 TRIM49C BTN2A3P TRIM49D1

6.38e-0487844SM00449
DomainMHC_I/II-like_Ag-recog

RAET1G ULBP2 RAET1L

6.61e-0438843IPR011162
DomainSPRY

TRIM49 TRIM49C BTN2A3P TRIM49D1

8.54e-0494844PF00622
DomainSPRY_dom

TRIM49 TRIM49C BTN2A3P TRIM49D1

8.54e-0494844IPR003877
DomainB30.2/SPRY

TRIM49 TRIM49C BTN2A3P TRIM49D1

8.88e-0495844IPR001870
DomainB302_SPRY

TRIM49 TRIM49C BTN2A3P TRIM49D1

8.88e-0495844PS50188
DomainDOCK_C

DOCK8 DOCK7

1.07e-0311842IPR010703
DomainDHR-1_domain

DOCK8 DOCK7

1.07e-0311842IPR027007
DomainDHR_2

DOCK8 DOCK7

1.07e-0311842PS51651
DomainDHR_1

DOCK8 DOCK7

1.07e-0311842PS51650
DomainDOCK-C2

DOCK8 DOCK7

1.07e-0311842PF14429
DomainDHR-2

DOCK8 DOCK7

1.07e-0311842IPR027357
DomainDHR-2

DOCK8 DOCK7

1.07e-0311842PF06920
DomainDOCK

DOCK8 DOCK7

1.07e-0311842IPR026791
DomainQuinoprot_gluc/sorb_DH

EML5 HHIPL2

1.28e-0312842IPR011041
DomainFerritin-like_SF

TCEAL5 COQ7

1.76e-0314842IPR009078
DomainIG_MHC

RAET1G ULBP2 RAET1L

2.50e-0360843PS00290
DomainCH

SYNE1 ACTN1 TAGLN

3.14e-0365843SM00033
DomainCH

SYNE1 ACTN1 TAGLN

3.87e-0370843PF00307
Domain-

SYNE1 ACTN1 TAGLN

4.02e-03718431.10.418.10
DomainCH

SYNE1 ACTN1 TAGLN

4.35e-0373843PS50021
DomainCH-domain

SYNE1 ACTN1 TAGLN

4.69e-0375843IPR001715
DomainActinin_actin-bd_CS

SYNE1 ACTN1

4.76e-0323842IPR001589
DomainSpectrin

SYNE1 ACTN1

4.76e-0323842PF00435
DomainACTININ_2

SYNE1 ACTN1

4.76e-0323842PS00020
DomainACTININ_1

SYNE1 ACTN1

4.76e-0323842PS00019
DomainHECT

HECW2 HECTD1

6.52e-0327842PF00632
DomainHECTc

HECW2 HECTD1

6.52e-0327842SM00119
DomainHECT_dom

HECW2 HECTD1

6.52e-0327842IPR000569
DomainHECT

HECW2 HECTD1

6.52e-0327842PS50237
DomainSpectrin_repeat

SYNE1 ACTN1

7.50e-0329842IPR002017
Pubmed

Human anaplastic thyroid carcinoma cells are sensitive to NK cell-mediated lysis via ULBP2/5/6 and chemoattract NK cells.

RAET1G ULBP2 RAET1L

1.46e-08386325212604
Pubmed

Direct interaction of the mouse cytomegalovirus m152/gp40 immunoevasin with RAE-1 isoforms.

RAET1G ULBP2 RAET1L

5.83e-08486320166740
Pubmed

Isolation and characterization of retinoic acid-inducible cDNA clones in F9 cells: a novel cDNA family encodes cell surface proteins sharing partial homology with MHC class I molecules.

RAET1G ULBP2 RAET1L

5.83e-0848638882725
Pubmed

Cutting edge: tumor rejection mediated by NKG2D receptor-ligand interaction is dependent upon perforin.

RAET1G ULBP2 RAET1L

5.83e-08486312421908
Pubmed

NKG2D-mediated natural killer cell protection against cytomegalovirus is impaired by viral gp40 modulation of retinoic acid early inducible 1 gene molecules.

RAET1G ULBP2 RAET1L

5.83e-08486312756263
Pubmed

Murine NKG2D ligands: "double, double toil and trouble".

RAET1G ULBP2 RAET1L

5.83e-08486319081632
Pubmed

MULT1E/mIL-12: a novel bifunctional protein for natural killer cell activation.

RAET1G ULBP2 RAET1L

1.45e-07586324572784
Pubmed

Genomic structures and characterization of Rae1 family members encoding GPI-anchored cell surface proteins and expressed predominantly in embryonic mouse brain.

RAET1G ULBP2 RAET1L

1.45e-0758638982867
Pubmed

Crystal structures of RAE-1beta and its complex with the activating immunoreceptor NKG2D.

RAET1G ULBP2 RAET1L

2.90e-07686311825567
Pubmed

Single nucleotide polymorphism analysis of the NKG2D ligand cluster on the long arm of chromosome 6: Extensive polymorphisms and evidence of diversity between human populations.

RAET1G ULBP2 RAET1L

2.90e-07686320219610
Pubmed

The NKG2D ligands RAE-1δ and RAE-1ε differ with respect to their receptor affinity, expression profiles and transcriptional regulation.

RAET1G ULBP2 RAET1L

2.90e-07686320976056
Pubmed

Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice.

RAET1G ULBP2 RAET1L

2.90e-07686310894171
Pubmed

Polymorphisms of NKG2D ligands: diverse RAET1/ULBP genes in northeastern Thais.

RAET1G ULBP2 RAET1L

2.90e-07686319688209
Pubmed

Ligands for murine NKG2D display heterogeneous binding behavior.

RAET1G ULBP2 RAET1L

2.90e-07686311857333
Pubmed

The herpesviral Fc receptor fcr-1 down-regulates the NKG2D ligands MULT-1 and H60.

RAET1G ULBP2 RAET1L

5.07e-07786316831899
Pubmed

Stress-regulated targeting of the NKG2D ligand Mult1 by a membrane-associated RING-CH family E3 ligase.

RAET1G ULBP2 RAET1L

5.07e-07786320870941
Pubmed

Critical role of the NKG2D receptor for NK cell-mediated control and immune escape of B-cell lymphoma.

RAET1G ULBP2 RAET1L

5.07e-07786326151313
Pubmed

NKG2D and Its Ligand MULT1 Contribute to Disease Progression in a Mouse Model of Multiple Sclerosis.

RAET1G ULBP2 RAET1L

5.07e-07786330787931
Pubmed

Cutting edge: murine UL16-binding protein-like transcript 1: a newly described transcript encoding a high-affinity ligand for murine NKG2D.

RAET1G ULBP2 RAET1L

5.07e-07786312370332
Pubmed

NKG2D ligand overexpression in lupus nephritis correlates with increased NK cell activity and differentiation in kidneys but not in the periphery.

RAET1G ULBP2 RAET1L

5.07e-07786325583577
Pubmed

A novel ligand for the NKG2D receptor activates NK cells and macrophages and induces tumor immunity.

RAET1G ULBP2 RAET1L

8.10e-07886312645935
Pubmed

Gut microbiota regulates NKG2D ligand expression on intestinal epithelial cells.

RAET1G ULBP2 RAET1L

1.21e-06986323136011
Pubmed

Cutting edge: Toll-like receptor signaling in macrophages induces ligands for the NKG2D receptor.

RAET1G ULBP2 RAET1L

1.21e-06986314764662
Pubmed

A cluster of ten novel MHC class I related genes on human chromosome 6q24.2-q25.3.

RAET1G ULBP2 RAET1L

1.73e-061086311827464
Pubmed

Cell Surface Downregulation of NK Cell Ligands by Patient-Derived HIV-1 Vpu and Nef Alleles.

RAET1G ULBP2 RAET1L

2.37e-061186326656785
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

ATG5 GTF2A1 FAM114A1 NCAPG GOPC USP11 UBR4 IREB2 RECQL ACTN1 NUDCD3 PSMD14 HECTD1 DDB2 CHUK

2.61e-061455861522863883
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ATG5 DLGAP1 CFAP91 ZBTB38 USP11 SYNE1 UBR4 CEP290 YLPM1 LRPAP1 POGZ ACTN1 HECTD1 CHUK

3.12e-061285861435914814
Pubmed

A human MAP kinase interactome.

DLGAP1 GTF2A1 SYNE1 CEP290 LRPAP1 POGZ ACTN1 CGNL1 MIDEAS

3.35e-0648686920936779
Pubmed

Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition.

ATG5 HECW2

6.04e-06286229260931
Pubmed

Trim43a, Trim43b, and Trim43c: Novel mouse genes expressed specifically in mouse preimplantation embryos.

TRIM49 TRIM49C CHUK

6.50e-061586319703589
Pubmed

Identification of a genomic reservoir for new TRIM genes in primate genomes.

TRIM49 TRIM49C TRIM49D1

1.37e-051986322144910
Pubmed

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.

ATG5 KCTD9 GTF2A1 FAM114A1 RSPH3 GOPC SULT2B1 TCHP FAM13C DOCK8 LENG1 POGZ ACTN1 PTCD3

1.51e-051477861431515488
Pubmed

Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 and ninein.

TCHP NIN

1.81e-05386221325031
Pubmed

The deubiquitinating enzyme USP11 controls an IkappaB kinase alpha (IKKalpha)-p53 signaling pathway in response to tumor necrosis factor alpha (TNFalpha).

USP11 CHUK

1.81e-05386217897950
Pubmed

A dominant-negative SOX18 mutant disrupts multiple regulatory layers essential to transcription factor activity.

SOX7 SOX18

1.81e-05386234570228
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

NCAPG TCHP CEP290 ZFP91 DOCK7 RECQL MPHOSPH8 PTCD3 NIN

3.17e-0564586925281560
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

USP11 UBR4 YLPM1 DOCK7 RECQL POGZ ACTN1 HECTD1 PTCD3

3.49e-0565386922586326
Pubmed

PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.

NCAPG DOCK8 YLPM1 DOCK7 HECTD1 NIN

3.53e-0524786632989298
Pubmed

Redundant roles of Sox17 and Sox18 in early cardiovascular development of mouse embryos.

SOX7 SOX18

3.61e-05486217610846
Pubmed

The interaction between IKKα and LC3 promotes type I interferon production through the TLR9-containing LAPosome.

ATG5 CHUK

3.61e-05486229717061
Pubmed

Differential NKG2D binding to highly related human NKG2D ligands ULBP2 and RAET1G is determined by a single amino acid in the alpha2 domain.

RAET1G ULBP2

3.61e-05486219424970
Pubmed

SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development.

SOX7 SOX18

3.61e-05486228619820
Pubmed

ULBP6/RAET1L is an additional human NKG2D ligand.

RAET1G RAET1L

6.01e-05586219658097
Pubmed

Tissue-specific expression of the human laminin alpha5-chain, and mapping of the gene to human chromosome 20q13.2-13.3 and to distal mouse chromosome 2 near the locus for the ragged (Ra) mutation.

LAMA2 SOX18

6.01e-0558629271224
Pubmed

[The possible curative therapy for rheumatoid arthritis--EBV infection control gene SAP and its application].

RBM5 IREB2

6.01e-05586218587224
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

GOPC DOCK8 ZFP91 RBM5 ELF1 RECQL POGZ BCL11A ACTN1 PSMD14 MIDEAS

8.65e-051103861134189442
Pubmed

Sox7 and Sox17 are strain-specific modifiers of the lymphangiogenic defects caused by Sox18 dysfunction in mice.

SOX7 SOX18

9.01e-05686219515696
Pubmed

Sox17 is essential for proper formation of the marginal zone of extraembryonic endoderm adjacent to a developing mouse placental disk.

SOX7 SOX18

9.01e-05686229635272
Pubmed

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus.

IFIH1 CHUK

9.01e-05686216177806
Pubmed

Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.

HECW2 UBR4 TRIM31 HECTD1

9.34e-059586429643511
Pubmed

A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition.

CEP290 NODAL NIN

1.07e-043786321725307
Pubmed

Proximity interactions among centrosome components identify regulators of centriole duplication.

KIAA1671 GOPC DOCK7 NIN

1.19e-0410186424613305
Pubmed

BBS mutations modify phenotypic expression of CEP290-related ciliopathies.

CEP290 BBS9

1.26e-04786223943788
Pubmed

Genome-wide screening and identification of novel proteolytic cleavage targets of caspase-8 and -10 in vitro.

GOPC DOP1A

1.26e-04786218288386
Pubmed

SOX7 expression is critically required in FLK1-expressing cells for vasculogenesis and angiogenesis during mouse embryonic development.

SOX7 SOX18

1.26e-04786228577909
Pubmed

A disease-linked ULBP6 polymorphism inhibits NKG2D-mediated target cell killing by enhancing the stability of NKG2D ligand binding.

ULBP2 RAET1L

1.26e-04786228559451
Pubmed

The DNA sequence and analysis of human chromosome 6.

ATG5 MBOAT1 GOPC SYNE1 BTN2A3P TRIM31 EDN1 TPBG

1.56e-0462286814574404
Pubmed

A conserved family of genes related to the testis determining gene, SRY.

SOX7 SOX18

1.68e-0488621614875
Pubmed

Roles for laminin in embryogenesis: exencephaly, syndactyly, and placentopathy in mice lacking the laminin alpha5 chain.

LAMA2 SOX18

1.68e-0488629852162
Pubmed

NLRC5 negatively regulates the NF-kappaB and type I interferon signaling pathways.

IFIH1 CHUK

1.68e-04886220434986
Pubmed

An Interaction Landscape of Ubiquitin Signaling.

USP11 UBR4 RECQL ACTN1 PSMD14 HECTD1 CHUK

1.94e-0448186728190767
Pubmed

Ultrastructural and biochemical localization of N-RAP at the interface between myofibrils and intercalated disks in the mouse heart.

NRAP ACTN1

2.15e-04986211732910
Pubmed

Human immunodeficiency virus type 1 Vpr links proteasomal degradation and checkpoint activation.

UBR4 DDB2

2.15e-04986217855541
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

FAM114A1 ZBTB38 NRAP USP11 SYNE1 LAMA2 RBM5

2.37e-0449786723414517
Pubmed

CFAP61 is required for sperm flagellum formation and male fertility in human and mouse.

RSPH3 CFAP91

2.68e-041086234792097
Pubmed

DAZ-interacting Protein 1 (Dzip1) Phosphorylation by Polo-like Kinase 1 (Plk1) Regulates the Centriolar Satellite Localization of the BBSome Protein during the Cell Cycle.

CEP290 BBS9

2.68e-041086227979967
Pubmed

A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.

FBXW8 EML5 DOCK7 RBM5 HECTD1

2.84e-0423286525515538
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

GTF2A1 NCAPG GOPC TCHP USP11 SYNE1 UBR4 EXOC3 LRPAP1 NUDCD3 PTCD3 NIN

2.92e-041487861233957083
Pubmed

The expression of Sox17 identifies and regulates haemogenic endothelium.

SOX7 SOX18

3.28e-041186223604320
Pubmed

The centriolar satellite protein AZI1 interacts with BBS4 and regulates ciliary trafficking of the BBSome.

CEP290 BBS9

3.28e-041186224550735
Pubmed

Nephrocystin proteins NPHP5 and Cep290 regulate BBSome integrity, ciliary trafficking and cargo delivery.

CEP290 BBS9

3.28e-041186225552655
Pubmed

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.

NCAPG UBR4 DOCK7 RECQL PSMD14 HECTD1 PTCD3

3.65e-0453486735032548
Pubmed

Essential and overlapping functions for mammalian Argonautes in microRNA silencing.

SOX18 NODAL

3.93e-041286219174539
Pubmed

Redundant roles of Sox17 and Sox18 in postnatal angiogenesis in mice.

SOX7 SOX18

3.93e-041286216895970
Pubmed

HIV-1 Vpr function is mediated by interaction with the damage-specific DNA-binding protein DDB1.

UBR4 DDB2

3.93e-041286217360488
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

KIAA1671 NCAPG YLPM1 DOCK7 POGZ ACTN1 MIDEAS

4.31e-0454986738280479
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

NCAPG ZFP91 EXOC3 POGZ MIDEAS DDB2

4.46e-0439486627248496
Pubmed

POGZ Is Required for Silencing Mouse Embryonic β-like Hemoglobin and Human Fetal Hemoglobin Expression.

POGZ BCL11A

4.63e-041386229898395
Pubmed

Cytoplasmic plaque formation in hemidesmosome development is dependent on SoxF transcription factor function.

SOX7 SOX18

4.63e-041386222962592
Pubmed

Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool.

CEP290 NIN

4.63e-041386217920017
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

GOPC CEP290 YLPM1 RBM5 LRPAP1 NUDCD3 PSMD14 HECTD1

4.68e-0473386834672954
Pubmed

The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.

DOCK7 POGZ ACTN1 CGNL1 TAGLN HECTD1

4.83e-0440086635013556
Pubmed

A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening.

ELF1 POGZ

5.39e-041486210976766
Pubmed

Numerous members of the Sox family of HMG box-containing genes are expressed in developing mouse teeth.

SOX7 SOX18

5.39e-04148628921394
Pubmed

Molecular dissection of plasmacytoid dendritic cell activation in vivo during a viral infection.

ATG5 CHUK

5.39e-041486230131424
Pubmed

Condensin I and II Complexes License Full Estrogen Receptor α-Dependent Enhancer Activation.

NCAPG HECTD1

5.39e-041486226166704
Pubmed

The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF.

TAGLN EDN1

5.39e-041486215610731
Pubmed

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.

DOCK8 DOCK7

5.39e-041486212432077
Pubmed

Activation of the NF-kappaB pathway by caspase 8 and its homologs.

IFIH1 CHUK

6.21e-041586211002417
Pubmed

Sox7, Sox17, and Sox18 Cooperatively Regulate Vascular Development in the Mouse Retina.

SOX7 SOX18

6.21e-041586226630461
Pubmed

C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals.

CEP290 NIN

6.21e-041586224469809
Pubmed

Dominant-negative Sox18 function inhibits dermal papilla maturation and differentiation in all murine hair types.

SOX7 SOX18

6.21e-041586228512199
Pubmed

SOXF factors regulate murine satellite cell self-renewal and function through inhibition of β-catenin activity.

SOX7 SOX18

6.21e-041586229882512
Pubmed

Talin 1 and 2 are required for myoblast fusion, sarcomere assembly and the maintenance of myotendinous junctions.

LAMA2 ACTN1

6.21e-041586219793892
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

KIAA1671 TCHP USP11 EXOC3 CGNL1 NUDCD3 NIN

6.46e-0458886738580884
Pubmed

Coronary veins determine the pattern of sympathetic innervation in the developing heart.

TAGLN EDN1

7.09e-041686223462468
Pubmed

CHIP E3 ligase mediates proteasomal degradation of the proliferation regulatory protein ALDH1L1 during the transition of NIH3T3 fibroblasts from G0/G1 to S-phase.

USP11 PSMD14

7.09e-041686229979702
Pubmed

A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition.

ZBTB38 YLPM1 DGKG EXOC3 ELF1 EDN1

7.13e-0443186633660365
Pubmed

Human transcription factor protein interaction networks.

KIAA1671 USP11 UBR4 YLPM1 ZFP91 ELF1 POGZ BCL11A PSMD14 MIDEAS PTCD3

7.86e-041429861135140242
Pubmed

Ciliopathy-associated gene Cc2d2a promotes assembly of subdistal appendages on the mother centriole during cilia biogenesis.

TCHP NIN

8.02e-041786224947469
CytobandEnsembl 112 genes in cytogenetic band chr6q25

RSPH3 SYNE1 RAET1G ULBP2 RAET1L

1.51e-05164865chr6q25
Cytoband6q25

SYNE1 ULBP2

2.26e-04128626q25
Cytoband11q14.3

TRIM49C TRIM49D1

1.66e-033286211q14.3
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM49 TRIM49C TRIM31 TRIM49D1

2.28e-049557459
GeneFamilySRY-boxes

SOX7 SOX18

1.61e-0319572757
GeneFamilyBardet-Biedl syndrome associated|BBSome

CEP290 BBS9

1.97e-0321572980
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

KIAA1671 SOX7 FAM13C HECW2 SOX18 GALNT18 EDN1

8.09e-08188867117dc80fa940e6aa1b0187a43fdde33f3fcb578f
ToppCellFetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KIAA1671 SOX7 FAM13C HECW2 SOX18 GALNT18 EDN1

1.11e-07197867b2b7f8dc8ca421441e4c99c4f5d18fbc1668d79f
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KIAA1671 SOX7 HECW2 SOX18 GALNT18 EDN1

1.40e-061818662c660fcf0404c155955b67ab2958d6e6b0e30024
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIAA1671 SOX7 HECW2 ULBP2 SOX18 EDN1

1.81e-061898669e58411e51019ca59e78d3e737d65d2bcbbea2be
ToppCellPCW_05-06-Endothelial-Endothelial_cycling-endo_proliferating1_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 ULBP2 SOX18 GALNT18 EDN1

1.86e-061908669a2244c3973aee7270646bf00db7727edb9decc5
ToppCellControl-Endothelial-VE_Capillary_B|Control / Disease state, Lineage and Cell class

SOX7 HECW2 SYNE1 SOX18 GALNT18 EDN1

1.92e-06191866322237793a1278bafb14e63cab688b353e352dcc
ToppCellfacs-Lung-Endomucin_-18m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX7 HECW2 SYNE1 SOX18 GALNT18 EDN1

1.98e-06192866ba3fe97786564dba1c8185f2802ce1b57f4f3cc9
ToppCellfacs-Lung-Endomucin_|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX7 HECW2 SYNE1 SOX18 GALNT18 EDN1

1.98e-0619286685d4d0df701451daf95e94a87a0096da1e86533b
ToppCelldroplet-Fat-Mat-18m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA1671 SOX7 SOX18 TAGLN GALNT18 EDN1

2.04e-0619386654024a373e42e1c0bcc327dc084564b83b63a9d4
ToppCelldroplet-Fat-Mat-18m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA1671 SOX7 SOX18 TAGLN GALNT18 EDN1

2.04e-0619386681d908594d2983ba7e7c1ec25afdde4315d9690e
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_capillary_(2)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 ULBP2 SOX18 GALNT18 EDN1

2.04e-061938664f38aae346ea3b4258744e9dc1e5aeb4fea13d06
ToppCellPCW_07-8.5-Endothelial-Endothelial_immature-endo_immature4_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 ULBP2 SOX18 GALNT18 EDN1

2.04e-0619386672d20ee257149b238016b44d183ce3fc24b8f621
ToppCellFetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KIAA1671 SOX7 HECW2 SOX18 GALNT18 EDN1

2.04e-06193866ff6e6b825d6c88148216c601580be3c28851ab5c
ToppCellPCW_13-14-Endothelial-Endothelial_mature-endo_capillary_(2)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 ULBP2 SOX18 GALNT18 EDN1

2.10e-061948663c31ac44e8cf4eca3ba7b8bfc05ad3e96a970956
ToppCellPCW_05-06-Endothelial|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 ULBP2 SOX18 GALNT18 EDN1

2.10e-0619486600291c62795a55a7e63b1db10c139d6a3298e55e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NCAPG FAM13C HECW2 RECQL NODAL TPBG

2.10e-0619486678dcb9d48259afabe73b41c5508a73a8d62339a4
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SOX7 HECW2 SOX18 CGNL1 GALNT18 EDN1

2.10e-06194866ea5e1bc8d9e27cabfe1fb833ca47ec0893593b12
ToppCellPCW_05-06-Endothelial-Endothelial_immature|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 ULBP2 SOX18 GALNT18 EDN1

2.10e-061948669bd25ea57f2da27bd200d1a8bf797fec77d172c7
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SOX7 HECW2 SOX18 CGNL1 GALNT18 EDN1

2.10e-06194866cceb7c88492bb6cd531e1c2651638da1ddf30931
ToppCelldroplet-Fat-Mat-18m-Endothelial-Cd36+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA1671 SOX7 SOX18 TAGLN GALNT18 EDN1

2.10e-0619486674d0eaa76f6d9af14110dfe5b4bf9751b99ff6e3
ToppCellPCW_05-06-Endothelial-Endothelial_mature|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 ULBP2 SOX18 GALNT18 EDN1

2.16e-0619586654fde2cfa51ab3a2d48d2426494ca6f0ce77f725
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 HECW2 SOX18 GALNT18 EDN1

2.16e-06195866a432d69b0172211ee4d53675936a1dc9ce1ae1f0
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature2_(1)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 ULBP2 SOX18 GALNT18 EDN1

2.23e-06196866b0288e28a6e6222a9e310eb6fe228c04b618db13
ToppCellPCW_10-12-Endothelial-Endothelial_mature-endo_capillary_(2)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 ULBP2 SOX18 GALNT18 EDN1

2.23e-061968662a2a93b89dcb98043cb1f8b422ac8c55e2edc37b
ToppCellPCW_10-12-Endothelial-Endothelial_immature-endo_immature1_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 ULBP2 SOX18 GALNT18 EDN1

2.23e-0619686629ed8b1c4cd730db8632fde6eece404f1883a86d
ToppCellnucseq-Endothelial-Endothelial_Vascular|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SOX7 HECW2 RIN2 SOX18 GALNT18 EDN1

2.23e-06196866686533fd3fba8e4df96b9dd1307e870e89db4332
ToppCellFetal_29-31_weeks-Endothelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KIAA1671 SOX7 HECW2 SOX18 GALNT18 EDN1

2.23e-061968663981f6c7487598f4f7ce4650ac0ac5bd41481d66
ToppCellPCW_10-12-Endothelial-Endothelial_immature-endo_immature2_(1)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 ULBP2 SOX18 GALNT18 EDN1

2.23e-061968660e8d649b50be2d707510b897bb97767b5847dff9
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 ULBP2 SOX18 GALNT18 EDN1

2.29e-061978664e9221cb02122aed2981c3c9157e847a3710e323
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-tip_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

KIAA1671 SOX7 FAM13C HECW2 SOX18 GALNT18

2.29e-06197866b212ff28ca2d1fea4140f186ab90941bdca21249
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SOX7 HECW2 ULBP2 SOX18 GALNT18 EDN1

2.29e-061978669b3d6fe76dd7d61a286a28d9466b5f2fece048e1
ToppCellwk_15-18-Endothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 HECW2 SOX18 GALNT18 EDN1

2.36e-06198866dcf453e22dba90c0ae349fa6c3d4c20758bb95af
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-intermediate_cap|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SOX7 HECW2 ULBP2 SOX18 GALNT18 EDN1

2.36e-0619886675270600b5b29187dfa86f01f8f927ae0621cda4
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_capillary|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SOX7 HECW2 SOX18 MIDEAS GALNT18 EDN1

2.43e-06199866772b3f60b83e29b958e1e70dadfd9f058ed4cb7c
ToppCellHematolymphoid-Endothelial-NOSTRIN|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SYNE1 LAMA2 ACTN1 CGNL1 BBS9 GALNT18

2.50e-06200866032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCellHematolymphoid-Endothelial-NOSTRIN---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SYNE1 LAMA2 ACTN1 CGNL1 BBS9 GALNT18

2.50e-0620086668fce28690246895fd33354b30960ebcc31aa4cc
ToppCellHematolymphoid-Endothelial-NOSTRIN-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SYNE1 LAMA2 ACTN1 CGNL1 BBS9 GALNT18

2.50e-06200866376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCellHematolymphoid-Endothelial-NOSTRIN--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SYNE1 LAMA2 ACTN1 CGNL1 BBS9 GALNT18

2.50e-062008667fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCellTracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_capillary|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SOX7 HECW2 ULBP2 SOX18 GALNT18 EDN1

2.50e-06200866746e8f61411f8e68b988152ab36561991f716a0a
ToppCellHematolymphoid-Endothelial-NOSTRIN----L2-6|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SYNE1 LAMA2 ACTN1 CGNL1 BBS9 GALNT18

2.50e-06200866878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCellHematolymphoid-Endothelial|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SYNE1 LAMA2 ACTN1 CGNL1 BBS9 GALNT18

2.50e-062008667136936d05ab344a560cf159684c881063b5430d
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOX7 FAM13C HECW2 SOX18 GALNT18

2.03e-05171865b3e6e31dfe3623b960ccf692fdbd236fa4039923
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_28|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX7 EML5 HECW2 SOX18 EDN1

2.15e-0517386566488d01e03264fb193285470901c9c4182fbae8
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MBOAT1 SP140L SWT1 HECW2 SYNE1

2.27e-0517586512f5fd83c7710fc0c77406f765d9cbd133433b8b
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK8 SYNE1 TAGLN EDN1 NIN

2.27e-05175865cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_LINC00507_CTXN3|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IFIH1 FBXW8 LAMA2 PCDH8 TPBG

2.40e-0517786596d639407f79669f3990138793d157b94273581c
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L5-6_RORB_LINC00320|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IFIH1 SOX7 FBXW8 TPBG KCNH5

2.40e-0517786501df8ab3285fa66b4805c555cfbfc4b3b16db919
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 SOX18 GALNT18 EDN1

2.60e-051808655861b44acfb8fe92c281c8355bf19c059b3dcd64
ToppCellCOVID-19-Endothelial_cells-Endothelial_cells_(other)|COVID-19 / group, cell type (main and fine annotations)

SOX7 HECW2 SOX18 GALNT18 EDN1

2.67e-0518186526eb4ee57a70dbf54e096b73129fda9dfda1f6ec
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOX7 HECW2 ULBP2 SOX18 EDN1

2.74e-0518286563b41b538b26bc899558807fd035e543611f8c52
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

NRAP FAM13C DGKG BCL11A TTTY10

2.96e-051858656baccb26f999145e51b91d94315bf8d4655bef31
ToppCellControl-Endothelial-VE_Capillary_A|World / Disease state, Lineage and Cell class

HECW2 SYNE1 RIN2 SOX18 GALNT18

2.96e-05185865a28187c2fd23564314b35759479ff2ca21f61485
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

FAM13C LAMA2 DGKG ACTN1 TAGLN

3.12e-05187865464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX7 SYNE1 SOX18 GALNT18 EDN1

3.12e-0518786552ffd4be374e329ac8d321063f061b826d252956
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIAA1671 SOX7 HECW2 SOX18 GALNT18

3.12e-05187865d9d10ed7c905778a29a0dc3ced3eef02a6b1de5c
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-endo_capillary_(2)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 ULBP2 SOX18 EDN1

3.12e-05187865106f50ad85a92403037214f0e94702230284837f
ToppCellControl-Endothelial-VE_Capillary_A|Control / Disease state, Lineage and Cell class

HECW2 SYNE1 RIN2 SOX18 GALNT18

3.12e-0518786554d7588172ac145ff5045ad9771636729ca3f0ca
ToppCellwk_08-11-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 SOX18 CGNL1 EDN1

3.12e-05187865a27aa97aa6508a3ffe92c2b6bb0511a95650a390
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 SOX18 GALNT18 EDN1

3.20e-05188865366a2d59b9c81d8a7659749f9c07efa46b49a39a
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOX7 DLGAP1 HECW2 SOX18 GALNT18

3.20e-051888650026c9479b30fb39daa91cfa220a88f9c9e65fe7
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature4_(5)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 SOX18 GALNT18 EDN1

3.20e-05188865b9c5d573fc5ab0f7f38c55d006f9576634b05462
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIAA1671 SOX7 HECW2 SOX18 GALNT18

3.28e-05189865db09d591b885ce2bc9e353f08b6694e2192582e1
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KIAA1671 HECW2 SYNE1 RIN2 GALNT18

3.28e-05189865b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCellCOVID-19-Heart-EC_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

HECW2 SYNE1 RIN2 SOX18 GALNT18

3.28e-05189865fe49852ba15f948b384d6b4c258927c70b741357
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIAA1671 SOX7 ULBP2 SOX18 EDN1

3.28e-05189865a34f008dfcee4012977bbc5b60de6f0329ca2f65
ToppCellControl-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

HECW2 SYNE1 RIN2 LAMA2 GALNT18

3.36e-051908657f3f419fffe02934b6f27b697f7a6401072491ed
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SOX7 HECW2 SOX18 GALNT18 EDN1

3.36e-0519086506bfb62b94b0faf467ef93d5bc5d08924c770098
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

KIAA1671 HECW2 SYNE1 RIN2 GALNT18

3.36e-051908650e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FAM13C DOCK8 DGKG ACTN1 TAGLN

3.36e-051908655681c211baeed4af82a2bbc13420f6a7b487581c
ToppCelldroplet-Lung-LUNG-30m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX7 SYNE1 SOX18 GALNT18 EDN1

3.36e-05190865e64b191f928935484e2c993d7f8af0572a617a3a
ToppCellPCW_07-8.5-Endothelial-Endothelial_cycling-endo_proliferating1_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 ULBP2 SOX18 EDN1

3.45e-05191865edfd5eeff69b5de19c5df3d899e42acd7e015913
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KIAA1671 HECW2 RIN2 SOX18 GALNT18

3.45e-051918651de0bdfd13bd930691564c2673f2e66393bc0255
ToppCellControl-Endothelial-VE_Capillary_B|World / Disease state, Lineage and Cell class

HECW2 SYNE1 SOX18 GALNT18 EDN1

3.45e-05191865c672c8e28d06d555335976b3f8bd2ea6d3b34aae
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 SOX18 GALNT18 EDN1

3.45e-05191865e3fc5c92491b6e334abffbf085c00a0b5fa1aed2
ToppCellPCW_07-8.5-Endothelial-Endothelial_immature-endo_immature3_(11)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 ULBP2 SOX18 EDN1

3.54e-051928657dbe3117a0f58ff2e838963d49f788a59a4351d7
ToppCelldroplet-Lung-nan-18m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX7 HECW2 SOX18 GALNT18 EDN1

3.54e-0519286545929c757d873fe314cc36d27abd265414635490
ToppCellPCW_07-8.5-Endothelial-Endothelial_cycling-endo_proliferating2_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 ULBP2 SOX18 EDN1

3.54e-05192865ac3d87aa301d30515c369bd7fc16f33b82173a85
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIAA1671 SOX7 SOX18 CGNL1 GALNT18

3.54e-051928655a0615fdc217554ccd611504b16e5d97628e207d
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KIAA1671 SOX7 HECW2 SOX18 GALNT18

3.54e-051928657197e401e563441ab94815f7619e032ebef9e586
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIAA1671 SOX7 HECW2 SOX18 GALNT18

3.54e-051928651f35efb0765e05f7f9c881849953bef3965be25a
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX7 HECW2 SOX18 GALNT18 EDN1

3.54e-051928656c089bde63dd5f16a07c5929fb49df600f0b21ab
ToppCelldroplet-Lung-nan-18m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX7 HECW2 SOX18 GALNT18 EDN1

3.54e-05192865beb336d3479821bdab7e8e2c58812f155e44e9a2
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature1_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SOX7 ULBP2 SOX18 GALNT18 EDN1

3.62e-051938652661ad9107ed9231e4afea4442a79051139a31df
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX7 SYNE1 SOX18 GALNT18 EDN1

3.62e-051938652218833749576ba1a0fc95bd155c781e7e1163c6
ToppCellPCW_10-12-Endothelial-Endothelial_cycling-endo_proliferating1_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 SOX18 GALNT18 EDN1

3.62e-05193865643f992dbce639e7d147924d8b8f455fcebf215a
ToppCellIPF-Endothelial-VE_Capillary_B|World / Disease state, Lineage and Cell class

SOX7 HECW2 SOX18 GALNT18 EDN1

3.62e-05193865d7750a7575ef257963b7f1c64fa67c52dbff797b
ToppCellPCW_05-06-Endothelial-Endothelial_cycling-endo_proliferating3_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 ULBP2 SOX18 EDN1

3.62e-05193865f7e4a390921780587b9bd084e495e646fa1ec74f
ToppCellCOPD-Endothelial|COPD / Disease state, Lineage and Cell class

SOX7 HECW2 SOX18 GALNT18 EDN1

3.62e-05193865093b28dcccb5841c995d0b33fae0efd6b88f97e0
ToppCellCOVID-19-Endothelial_cells-Inflamed_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

HECW2 SYNE1 SOX18 GALNT18 EDN1

3.62e-05193865979ebefa527f86bebeea5d94e626ee6c1cc7d53b
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOX7 NCAPG HECW2 SOX18 GALNT18

3.62e-05193865dd443b83d328a9069ffe19ac3d74066e922515a5
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature4_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 SOX18 GALNT18 EDN1

3.62e-0519386501c71aa48875b5ad6c50cc810a72862e72f26ad0
ToppCellPCW_07-8.5-Endothelial-Endothelial_immature-endo_immature1_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 ULBP2 SOX18 EDN1

3.71e-051948652e3a64bda7c76fd0c99e93de0215f236e8045d83
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 ULBP2 SOX18 EDN1

3.71e-051948658c88a0ddd61ad900426e312ca4ab13061c0380b8
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX7 FAM13C SOX18 GALNT18 EDN1

3.71e-0519486546e36817fd1ed27af8013375214c38c9a9271640
ToppCellIPF-Endothelial-VE_Capillary_B|IPF / Disease state, Lineage and Cell class

SOX7 HECW2 SOX18 GALNT18 EDN1

3.71e-05194865169a304d5c13f08c39fad4116f093bc4a0765e9d
ToppCellIPF-Endothelial|IPF / Disease state, Lineage and Cell class

SOX7 HECW2 SOX18 GALNT18 EDN1

3.71e-051948659591993aa2dcba3d09a0f1ea8b8f2439c26482d6
ToppCellfacs-Lung-Endomucin_-18m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX7 SYNE1 SOX18 GALNT18 EDN1

3.71e-05194865df56e23f1dcf1902d29392fcc947e0e268e1648b
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KIAA1671 SOX7 HECW2 SOX18 EDN1

3.71e-05194865fc2e0081005c0c496e41197a2d06e4a37708221f
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 ULBP2 SOX18 GALNT18

3.71e-0519486532ba2cf9b8726bc3c6e9dc24b54d22ff188bb12b
ToppCellPCW_05-06-Endothelial-Endothelial_cycling|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KIAA1671 SOX7 ULBP2 SOX18 EDN1

3.71e-05194865eb279e0d922de921343f0ae032a809f837d915b3
Drugmethyltrichlorosilane

SYNE1 EDN1 NIN

1.62e-067833CID000006399
Diseaselevel of UL16-binding protein 6 in blood serum

ULBP2 RAET1L

7.82e-062832OBA_2043185
Diseaseapolipoprotein A 1 measurement

PPP1R21 GTF2A1 TMEM62 ZBTB38 YLPM1 DOCK7 DGKG TAGLN MIDEAS DDB2

1.33e-048488310EFO_0004614
DiseaseMyopia

LAMA2 LRPAP1

8.02e-0415832C0027092
Diseasemyopia (is_implicated_in)

LAMA2 LRPAP1

9.14e-0416832DOID:11830 (is_implicated_in)
DiseaseBardet-Biedl syndrome 1 (disorder)

CEP290 BBS9

1.03e-0317832C2936862
Diseasemuscular dystrophy (is_implicated_in)

SYNE1 LAMA2

1.03e-0317832DOID:9884 (is_implicated_in)
DiseaseBardet-Biedl syndrome

CEP290 BBS9

1.16e-0318832cv:C0752166
Diseasesocial deprivation, COVID-19

RIN2 BCL11A

1.59e-0321832EFO_0009696, MONDO_0100096
DiseaseNeurodevelopmental Disorders

DLGAP1 DOCK8 POGZ

2.32e-0393833C1535926

Protein segments in the cluster

PeptideGeneStartEntry
MEKTKWLDIKGNHDA

TMEM62

131

Q0P6H9
WINNLQKEKKDSHLM

BTN2A3P

266

Q96KV6
VSRLWGKHKNKPDMN

ELF1

246

P32519
HEAWTDGKEAMLRQK

ACTN1

406

P12814
KRWSAMHEAAKQGRK

ASB15

176

Q8WXK1
MKFDELHQLKANNWK

DLGAP1

886

O14490
KWHSEKMAGKNLVAV

DOP1A

1541

Q5JWR5
KSQLHKKREDGEFWM

CAPN13

301

Q6MZZ7
MEKLNQLWEKAQRLH

LRPAP1

56

P30533
QKKDHKQLWMGLQND

ATG5

146

Q9H1Y0
NMKHLNARWSKLQEG

CFAP91

311

Q7Z4T9
ALKDKIEMGNKRWNS

IREB2

686

P48200
RDMKGPAHDKLWNQL

GOPC

226

Q9HD26
ANKQLELPRGWEMKH

HECW2

981

Q9P2P5
EAWKMLGLFRKHNKI

PTCD3

591

Q96EY7
LAHMFKDKGVWGNKQ

KCTD9

116

Q7L273
KWAKDMNRHFSKEDI

nan

1071

O00370
KNWMKGREHENASIL

KIAA1671

1086

Q9BY89
LPEDLKMAWAKKAHA

NRAP

1391

Q86VF7
KMAWAKKAHALQSEL

NRAP

1396

Q86VF7
QSHELKVHEMLKKGW

NUDCD3

321

Q8IVD9
FMQGKRQKEIWHLLK

CHUK

641

O15111
MNILPKKSWHVRNKD

LENG1

1

Q96BZ8
WLRLKNNMGAHEEKK

KCNH5

811

Q8NCM2
EKHMKKWHSDRVLNN

BCL11A

816

Q9H165
AKEHMLRTNWKNRKG

FBXW8

186

Q8N3Y1
EVKNAMKKLWGRNVF

OR4S2

291

Q8NH73
LKKDLINHMQSGLWA

PCDH8

936

O95206
KINDGQWHKIKIMRS

LAMA2

2841

P24043
HWMLEAQLAKIKLEK

PPP1R21

581

Q6ZMI0
DGKELWNLRMHKKKV

DDB2

231

Q92466
WMEANQKKLVIQGKH

RBM5

156

P52756
LKDNGQIRFMKKLDW

BBS9

271

Q3SYG4
QNRRMKWKKDHKLPN

HOXB4

211

P17483
KHPEKFNSRMKNKLW

DGKG

601

P49619
EKQGWRHVRIKQMGK

HECTD1

1206

Q9ULT8
KDMTHWRQNTEKLDK

DOCK7

1446

Q96N67
RLTWLQNMAEKHTKK

DOCK8

1641

Q8NF50
KNEMENERWHLGKTI

CGNL1

936

Q0VF96
KDTKGAQKVINWHMK

CEP290

1336

O15078
MWDQEKDHLKKFNEL

COQ7

86

Q99807
WAIQMEKKAAKEGNR

IFIH1

581

Q9BYX4
AKAKRMKLHWQFSQG

GALNT18

546

Q6P9A2
HMKLLEVNWKRKGFH

MBOAT1

216

Q6ZNC8
WDHRGLKFGLMQLDK

LYG2

116

Q86SG7
DQWKMAERKLFNKGI

MIDEAS

831

Q6PJG2
WDIADKKMLNKVNLG

EML5

1721

Q05BV3
EQHLNELMTKKWLLG

EXOC3

551

O60645
GRLMALQEDRKNKKW

HHIPL2

526

Q6UWX4
AEDIMEKDWNNHKKG

EDN1

131

P05305
EWMKLEDFQKHLDGK

MPHOSPH8

541

Q99549
TPDKLNKAMKRAHDW

FAM114A1

381

Q8IWE2
ELEQKMLLNLHKKSW

PSMD14

211

O00487
HNAELSKMLGKSWKA

SOX7

71

Q9BT81
DMKSWGLLQKNNHKM

TRIM31

316

Q9BZY9
HREKLLQKMQSLWEK

TRIM49

136

P0CI25
DHIKGWLRMKGKDNF

SULT2B1

191

O00204
GDWKKHVETNSRLMK

SYNE1

916

Q8NF91
KWLKHPGALEKQMSR

NODAL

161

Q96S42
NQQKRLSWDKLDHLM

NIN

1831

Q8N4C6
LHKKWKEQAREMADT

POGZ

1276

Q7Z3K3
RGDPNWFMKKAQEHK

TAGLN

146

Q01995
VLKWMNDLAKGRKQL

FAM13C

326

Q8NE31
NKWSHLLVQREKMKE

SWT1

171

Q5T5J6
PMWLDKIKKRLNEHG

SP140L

511

Q9H930
SREGWGNLKELMKHA

ACSM3

201

Q53FZ2
VKQAMQKHLLQGWLR

NCAPG

261

Q9BPX3
KWVHAEMVNKNSELK

RECQL

171

P46063
KNKWKFHLKDGIMNL

GTF2A1

346

P52655
LKDFHMADGSWKQLK

RIN2

611

Q8WYP3
RRKKQQWEIMHKHNE

RSPH3

376

Q86UC2
HDKERLEKWLKNMKR

THAP5

31

Q7Z6K1
HREKLLQKMQSLWEK

TRIM49C

136

P0CI26
QEELRKKQKMGGFHW

TCEAL5

156

Q5H9L2
NAQLHWKRMENLKEE

TMEM104

71

Q8NE00
LMDWEEAHEKNRKNK

TTTY10

6

Q9BZA0
VHPGARKMKEKWEND

RAET1G

161

Q6H3X3
EHWKKNNPKLREMEL

TCHP

141

Q9BT92
VHPGARKMKEKWEND

RAET1L

161

Q5VY80
KLKEINKMADHWETA

YLPM1

1976

P49750
WAAEEHREKLLKKMQ

TRIM49D1

131

C9J1S8
HNAVLSKMLGKAWKE

SOX18

111

P35713
LNRKGIKKWMHNIRD

TPBG

376

Q13641
QKASLNWHMKKHDAD

ZFP91

411

Q96JP5
LKKMRKVNWRKEHGN

ZBTB38

931

Q8NAP3
VHPGARKMKEKWEND

ULBP2

161

Q9BZM5
VNWIKDHLIKQGMKA

UBR4

1051

Q5T4S7
KQHQLATKKLDLWML

USP11

806

P51784