Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity	NANOG NANOGP8	8.29e-06	4	24	2	GO:0001010
GeneOntologyMolecularFunction	odorant binding	OR12D3 OR2A4 OR2A7	4.61e-04	127	24	3	GO:0005549
GeneOntologyMolecularFunction	lysine-acetylated histone binding	NANOG NANOGP8	5.90e-04	30	24	2	GO:0070577
GeneOntologyMolecularFunction	acetylation-dependent protein binding	NANOG NANOGP8	6.30e-04	31	24	2	GO:0140033
GeneOntologyMolecularFunction	olfactory receptor activity	OR12D3 OR11H4 OR2A4 OR2A7	1.61e-03	431	24	4	GO:0004984
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR12D3 OR11H4 OR2A4 EDNRA OR2A7	3.54e-03	884	24	5	GO:0004930
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	CSF3R OR12D3 OR11H4 OR2A4 EDNRA OR2A7	4.47e-03	1353	24	6	GO:0004888
GeneOntologyBiologicalProcess	negative regulation of endodermal cell fate specification	NANOG NANOGP8	7.13e-06	4	23	2	GO:0042664
GeneOntologyBiologicalProcess	regulation of endodermal cell fate specification	NANOG NANOGP8	1.19e-05	5	23	2	GO:0042663
GeneOntologyBiologicalProcess	negative regulation of endodermal cell differentiation	NANOG NANOGP8	1.78e-05	6	23	2	GO:1903225
GeneOntologyBiologicalProcess	negative regulation of cell fate specification	NANOG NANOGP8	3.32e-05	8	23	2	GO:0009996
GeneOntologyBiologicalProcess	regulation of endodermal cell differentiation	NANOG NANOGP8	5.32e-05	10	23	2	GO:1903224
GeneOntologyBiologicalProcess	endodermal cell fate specification	NANOG NANOGP8	6.50e-05	11	23	2	GO:0001714
GeneOntologyBiologicalProcess	cell dedifferentiation	NANOG NANOGP8	1.24e-04	15	23	2	GO:0043697
GeneOntologyBiologicalProcess	dedifferentiation	NANOG NANOGP8	1.24e-04	15	23	2	GO:0043696
GeneOntologyBiologicalProcess	negative regulation of cell fate commitment	NANOG NANOGP8	1.60e-04	17	23	2	GO:0010454
GeneOntologyBiologicalProcess	endodermal cell fate commitment	NANOG NANOGP8	1.80e-04	18	23	2	GO:0001711
GeneOntologyBiologicalProcess	regulation of stem cell division	NANOG NANOGP8	1.80e-04	18	23	2	GO:2000035
GeneOntologyBiologicalProcess	renal sodium ion transport	PON3 EDNRA	1.80e-04	18	23	2	GO:0003096
GeneOntologyBiologicalProcess	mesodermal cell fate commitment	NANOG NANOGP8	2.97e-04	23	23	2	GO:0001710
GeneOntologyBiologicalProcess	regulation of cell fate specification	NANOG NANOGP8	4.74e-04	29	23	2	GO:0042659
GeneOntologyBiologicalProcess	negative regulation of stem cell differentiation	NANOG NANOGP8	6.15e-04	33	23	2	GO:2000737
GeneOntologyBiologicalProcess	mesodermal cell differentiation	NANOG NANOGP8	6.92e-04	35	23	2	GO:0048333
GeneOntologyBiologicalProcess	cell fate commitment involved in formation of primary germ layer	NANOG NANOGP8	7.74e-04	37	23	2	GO:0060795
GeneOntologyBiologicalProcess	endodermal cell differentiation	NANOG NANOGP8	8.16e-04	38	23	2	GO:0035987
GeneOntologyCellularComponent	mitotic spindle midzone	OR2A4 OR2A7	1.38e-04	16	23	2	GO:1990023
GeneOntologyCellularComponent	Flemming body	OR2A4 OR2A7	7.13e-04	36	23	2	GO:0090543
GeneOntologyCellularComponent	spindle midzone	OR2A4 OR2A7	8.81e-04	40	23	2	GO:0051233
GeneOntologyCellularComponent	mitotic spindle pole	OR2A4 OR2A7	1.02e-03	43	23	2	GO:0097431
GeneOntologyCellularComponent	cleavage furrow	OR2A4 OR2A7	2.04e-03	61	23	2	GO:0032154
GeneOntologyCellularComponent	cell division site	OR2A4 OR2A7	3.47e-03	80	23	2	GO:0032153
MousePheno	abnormal white adipose tissue morphology	OR12D3 PON3 AMER1 CREB3 HR	5.52e-05	321	19	5	MP:0002970
MousePheno	absent primitive endoderm	NANOG NANOGP8	6.27e-05	9	19	2	MP:0011185
MousePheno	absent extraembryonic ectoderm	NANOG NANOGP8	1.82e-04	15	19	2	MP:0002583
MousePheno	absent embryonic epiblast	NANOG NANOGP8	2.08e-04	16	19	2	MP:0011184
MousePheno	decreased white adipose tissue amount	OR12D3 AMER1 HR	2.32e-04	90	19	3	MP:0001783
Domain	-	INTS9 DCLRE1A	2.96e-04	20	24	2	3.60.15.10
Domain	Metallo-B-lactamas	INTS9 DCLRE1A	2.96e-04	20	24	2	IPR001279
Domain	GPCR_Rhodpsn_7TM	OR12D3 OR11H4 OR2A4 EDNRA OR2A7	1.41e-03	670	24	5	IPR017452
Domain	Olfact_rcpt	OR12D3 OR11H4 OR2A4 OR2A7	1.47e-03	393	24	4	IPR000725
Domain	7tm_1	OR12D3 OR11H4 OR2A4 EDNRA OR2A7	1.48e-03	677	24	5	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR12D3 OR11H4 OR2A4 EDNRA OR2A7	1.56e-03	685	24	5	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR12D3 OR11H4 OR2A4 EDNRA OR2A7	1.62e-03	691	24	5	PS50262
Domain	GPCR_Rhodpsn	OR12D3 OR11H4 OR2A4 EDNRA OR2A7	1.63e-03	692	24	5	IPR000276
Pubmed	Nanog1 in NTERA-2 and recombinant NanogP8 from somatic cancer cells adopt multiple protein conformations and migrate at multiple M.W species.	NANOG NANOGP8	4.56e-07	2	24	2	24598770
Pubmed	Differential expression of nanog1 and nanogp8 in colon cancer cells.	NANOG NANOGP8	4.56e-07	2	24	2	22079639
Pubmed	Expression of NANOG and NANOGP8 in a variety of undifferentiated and differentiated human cells.	NANOG NANOGP8	4.56e-07	2	24	2	21136380
Pubmed	Functional evidence that the self-renewal gene NANOG regulates human tumor development.	NANOG NANOGP8	4.56e-07	2	24	2	19415763
Pubmed	Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells.	NANOG NANOGP8	1.37e-06	3	24	2	25825768
Pubmed	Epithelial cell senescence induces pulmonary fibrosis through Nanog-mediated fibroblast activation.	NANOG NANOGP8	1.37e-06	3	24	2	31891567
Pubmed	Chromatin decondensation and nuclear softening accompany Nanog downregulation in embryonic stem cells.	NANOG NANOGP8	1.37e-06	3	24	2	23200040
Pubmed	Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4.	NANOG NANOGP8	1.37e-06	3	24	2	19447925
Pubmed	Selenium Augments microRNA Directed Reprogramming of Fibroblasts to Cardiomyocytes via Nanog.	NANOG NANOGP8	1.37e-06	3	24	2	26975336
Pubmed	Nanog suppresses cell migration by downregulating thymosin β4 and Rnd3.	NANOG NANOGP8	1.37e-06	3	24	2	23329853
Pubmed	The pluripotency factor NANOG controls primitive hematopoiesis and directly regulates Tal1.	NANOG NANOGP8	1.37e-06	3	24	2	30814124
Pubmed	Identification of two distinct transactivation domains in the pluripotency sustaining factor nanog.	NANOG NANOGP8	1.37e-06	3	24	2	14728807
Pubmed	Locating and Characterizing a Transgene Integration Site by Nanopore Sequencing.	NANOG NANOGP8	1.37e-06	3	24	2	30837263
Pubmed	NANOG alone induces germ cells in primed epiblast in vitro by activation of enhancers.	NANOG NANOGP8	1.37e-06	3	24	2	26751055
Pubmed	Isolation and characterization of the murine Nanog gene promoter.	NANOG NANOGP8	1.37e-06	3	24	2	15916719
Pubmed	Nanog induces hyperplasia without initiating tumors.	NANOG NANOGP8	1.37e-06	3	24	2	25173648
Pubmed	Distinct Contributions of Tryptophan Residues within the Dimerization Domain to Nanog Function.	NANOG NANOGP8	1.37e-06	3	24	2	27939294
Pubmed	Epigenetic regulation of Nanog gene in embryonic stem and trophoblast stem cells.	NANOG NANOGP8	1.37e-06	3	24	2	17352742
Pubmed	The molecular logic of Nanog-induced self-renewal in mouse embryonic stem cells.	NANOG NANOGP8	1.37e-06	3	24	2	30846691
Pubmed	Generation of germline-competent induced pluripotent stem cells.	NANOG NANOGP8	1.37e-06	3	24	2	17554338
Pubmed	Multiple phases in regulation of Nanog expression during pre-implantation development.	NANOG NANOGP8	1.37e-06	3	24	2	26660234
Pubmed	Nanog retrotransposed genes with functionally conserved open reading frames.	NANOG NANOGP8	1.37e-06	3	24	2	16845474
Pubmed	Nanog overcomes reprogramming barriers and induces pluripotency in minimal conditions.	NANOG NANOGP8	1.37e-06	3	24	2	21194951
Pubmed	OCT4/SOX2-independent Nanog autorepression modulates heterogeneous Nanog gene expression in mouse ES cells.	NANOG NANOGP8	1.37e-06	3	24	2	23178592
Pubmed	Stochastic NANOG fluctuations allow mouse embryonic stem cells to explore pluripotency.	NANOG NANOGP8	1.37e-06	3	24	2	25005472
Pubmed	Cell-permeant recombinant Nanog protein promotes pluripotency by inhibiting endodermal specification.	NANOG NANOGP8	1.37e-06	3	24	2	24681518
Pubmed	Roles of the Nanog protein in murine F9 embryonal carcinoma cells and their endoderm-differentiated counterparts.	NANOG NANOGP8	1.37e-06	3	24	2	16773043
Pubmed	Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming.	NANOG NANOGP8	1.37e-06	3	24	2	23665121
Pubmed	Ectopic overexpression of Nanog induces tumorigenesis in non-tumorous fibroblasts.	NANOG NANOGP8	1.37e-06	3	24	2	26733157
Pubmed	Identification and regulation of a stage-specific stem cell niche enriched by Nanog-positive spermatogonial stem cells in the mouse testis.	NANOG NANOGP8	1.37e-06	3	24	2	22388986
Pubmed	NANOG changes in mouse kidneys with age.	NANOG NANOGP8	1.37e-06	3	24	2	16313224
Pubmed	Crystal structure and DNA binding of the homeodomain of the stem cell transcription factor Nanog.	NANOG NANOGP8	1.37e-06	3	24	2	18177668
Pubmed	Transient Activation of Mitoflashes Modulates Nanog at the Early Phase of Somatic Cell Reprogramming.	NANOG NANOGP8	1.37e-06	3	24	2	26549484
Pubmed	mNanog possesses dorsal mesoderm-inducing ability by modulating both BMP and Activin/nodal signaling in Xenopus ectodermal cells.	NANOG NANOGP8	1.37e-06	3	24	2	23071603
Pubmed	Nanog promotes transfer of pluripotency after cell fusion.	NANOG NANOGP8	1.37e-06	3	24	2	16791199
Pubmed	Expression of Nanog gene promotes NIH3T3 cell proliferation.	NANOG NANOGP8	1.37e-06	3	24	2	16259959
Pubmed	Overexpression of NANOG in human ES cells enables feeder-free growth while inducing primitive ectoderm features.	NANOG NANOGP8	1.37e-06	3	24	2	16501172
Pubmed	Effect of Nanog overexpression on the metastatic potential of a mouse melanoma cell line B16-BL6.	NANOG NANOGP8	1.37e-06	3	24	2	33665763
Pubmed	A novel NK-type homeobox gene, ENK (early embryo specific NK), preferentially expressed in embryonic stem cells.	NANOG NANOGP8	1.37e-06	3	24	2	12609610
Pubmed	Heparan sulfate regulates self-renewal and pluripotency of embryonic stem cells.	NANOG NANOGP8	1.37e-06	3	24	2	18024963
Pubmed	Regulated fluctuations in nanog expression mediate cell fate decisions in embryonic stem cells.	NANOG NANOGP8	1.37e-06	3	24	2	19582141
Pubmed	The pluripotency factor Nanog regulates pericentromeric heterochromatin organization in mouse embryonic stem cells.	NANOG NANOGP8	1.37e-06	3	24	2	27125671
Pubmed	Identification of genes regulated by nanog which is involved in ES cells pluripotency and early differentiation.	NANOG NANOGP8	1.37e-06	3	24	2	18442017
Pubmed	Cutting edge: Hypoxia-induced Nanog favors the intratumoral infiltration of regulatory T cells and macrophages via direct regulation of TGF-β1.	NANOG NANOGP8	1.37e-06	3	24	2	24227785
Pubmed	NANOG induction of fetal liver kinase-1 (FLK1) transcription regulates endothelial cell proliferation and angiogenesis.	NANOG NANOGP8	1.37e-06	3	24	2	21119109
Pubmed	Pluripotency factor NANOG promotes germ cell maintenance in vitro without triggering dedifferentiation of spermatogonial stem cells.	NANOG NANOGP8	1.37e-06	3	24	2	32145514
Pubmed	Nanog is the gateway to the pluripotent ground state.	NANOG NANOGP8	1.37e-06	3	24	2	19703398
Pubmed	Reprogramming capacity of Nanog is functionally conserved in vertebrates and resides in a unique homeodomain.	NANOG NANOGP8	1.37e-06	3	24	2	22028025
Pubmed	Nanog safeguards pluripotency and mediates germline development.	NANOG NANOGP8	1.37e-06	3	24	2	18097409
Pubmed	Context-Dependent Functions of NANOG Phosphorylation in Pluripotency and Reprogramming.	NANOG NANOGP8	1.37e-06	3	24	2	28457890
Pubmed	Nanog Fluctuations in Embryonic Stem Cells Highlight the Problem of Measurement in Cell Biology.	NANOG NANOGP8	1.37e-06	3	24	2	28636920
Pubmed	Requirement of Nanog dimerization for stem cell self-renewal and pluripotency.	NANOG NANOGP8	1.37e-06	3	24	2	18436640
Pubmed	Heterogeneities in Nanog Expression Drive Stable Commitment to Pluripotency in the Mouse Blastocyst.	NANOG NANOGP8	1.37e-06	3	24	2	25753417
Pubmed	Stochastic promoter activation affects Nanog expression variability in mouse embryonic stem cells.	NANOG NANOGP8	1.37e-06	3	24	2	25410303
Pubmed	Nanog co-regulated by Nodal/Smad2 and Oct4 is required for pluripotency in developing mouse epiblast.	NANOG NANOGP8	1.37e-06	3	24	2	24929238
Pubmed	Nanog and transcriptional networks in embryonic stem cell pluripotency.	NANOG NANOGP8	1.37e-06	3	24	2	17211451
Pubmed	The pluripotency factor nanog promotes breast cancer tumorigenesis and metastasis.	NANOG NANOGP8	1.37e-06	3	24	2	23770853
Pubmed	The stem cell pluripotency factor NANOG activates transcription with two unusually potent subdomains at its C terminus.	NANOG NANOGP8	1.37e-06	3	24	2	15502159
Pubmed	A distinct expression pattern in mammalian testes indicates a conserved role for NANOG in spermatogenesis.	NANOG NANOGP8	1.37e-06	3	24	2	20539761
Pubmed	Genome editing demonstrates that the -5 kb Nanog enhancer regulates Nanog expression by modulating RNAPII initiation and/or recruitment.	NANOG NANOGP8	1.37e-06	3	24	2	33334884
Pubmed	NANOG promotes cancer stem cell characteristics and prostate cancer resistance to androgen deprivation.	NANOG NANOGP8	1.37e-06	3	24	2	21499299
Pubmed	Nanog variability and pluripotency regulation of embryonic stem cells--insights from a mathematical model analysis.	NANOG NANOGP8	1.37e-06	3	24	2	20574542
Pubmed	lincRNAs act in the circuitry controlling pluripotency and differentiation.	NANOG NANOGP8	1.37e-06	3	24	2	21874018
Pubmed	Cell signalling regulates dynamics of Nanog distribution in embryonic stem cell populations.	NANOG NANOGP8	1.37e-06	3	24	2	23054952
Pubmed	Phosphorylation of NANOG by casein kinase I regulates embryonic stem cell self-renewal.	NANOG NANOGP8	1.37e-06	3	24	2	33107035
Pubmed	Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes.	NANOG NANOGP8	1.37e-06	3	24	2	18584034
Pubmed	Nanog-independent reprogramming to iPSCs with canonical factors.	NANOG NANOGP8	1.37e-06	3	24	2	24527385
Pubmed	Alternative splicing produces Nanog protein variants with different capacities for self-renewal and pluripotency in embryonic stem cells.	NANOG NANOGP8	1.37e-06	3	24	2	21969378
Pubmed	Aromatic residues in the C-terminal domain 2 are required for Nanog to mediate LIF-independent self-renewal of mouse embryonic stem cells.	NANOG NANOGP8	1.37e-06	3	24	2	18086680
Pubmed	The phosphoinositide-3-kinase/Akt pathway mediates the transient increase in Nanog expression during differentiation of F9 cells.	NANOG NANOGP8	1.37e-06	3	24	2	20661723
Pubmed	NANOG restores the impaired myogenic differentiation potential of skeletal myoblasts after multiple population doublings.	NANOG NANOGP8	1.37e-06	3	24	2	29245050
Pubmed	Forced expression of Nanog in hematopoietic stem cells results in a gammadeltaT-cell disorder.	NANOG NANOGP8	1.37e-06	3	24	2	17360937
Pubmed	Cancer vaccination drives Nanog-dependent evolution of tumor cells toward an immune-resistant and stem-like phenotype.	NANOG NANOGP8	1.37e-06	3	24	2	22337995
Pubmed	Mapping dynamic histone acetylation patterns to gene expression in nanog-depleted murine embryonic stem cells.	NANOG NANOGP8	1.37e-06	3	24	2	21187909
Pubmed	Two olfactory receptors-OR2A4/7 and OR51B5-differentially affect epidermal proliferation and differentiation.	OR2A4 OR2A7	1.37e-06	3	24	2	27315375
Pubmed	H3K9 tri-methylation at Nanog times differentiation commitment and enables the acquisition of primitive endoderm fate.	NANOG NANOGP8	1.37e-06	3	24	2	35976266
Pubmed	Functional analysis of two Sp1/Sp3 binding sites in murine Nanog gene promoter.	NANOG NANOGP8	1.37e-06	3	24	2	16541131
Pubmed	Role of Nanog in the maintenance of marrow stromal stem cells during post natal bone regeneration.	NANOG NANOGP8	1.37e-06	3	24	2	22142851
Pubmed	The pluripotency rheostat Nanog functions as a dimer.	NANOG NANOGP8	1.37e-06	3	24	2	18290762
Pubmed	NANOG amplifies STAT3 activation and they synergistically induce the naive pluripotent program.	NANOG NANOGP8	1.37e-06	3	24	2	24462001
Pubmed	Reprogramming of mouse fibroblasts into induced pluripotent stem cells with Nanog.	NANOG NANOGP8	1.37e-06	3	24	2	23333380
Pubmed	A negative feedback loop of transcription factors that controls stem cell pluripotency and self-renewal.	NANOG NANOGP8	1.37e-06	3	24	2	16790525
Pubmed	Primitive endoderm differentiates via a three-step mechanism involving Nanog and RTK signaling.	NANOG NANOGP8	1.37e-06	3	24	2	22172669
Pubmed	Nanog dynamics in single embryonic stem cells.	NANOG NANOGP8	1.37e-06	3	24	2	26760119
Pubmed	Regulation of Nanog expression by phosphoinositide 3-kinase-dependent signaling in murine embryonic stem cells.	NANOG NANOGP8	1.37e-06	3	24	2	17204467
Pubmed	CrxOS maintains the self-renewal capacity of murine embryonic stem cells.	NANOG NANOGP8	1.37e-06	3	24	2	19800316
Pubmed	Nanog is dispensable for the generation of induced pluripotent stem cells.	NANOG NANOGP8	1.37e-06	3	24	2	24461999
Pubmed	Nanog-dependent feedback loops regulate murine embryonic stem cell heterogeneity.	NANOG NANOGP8	1.37e-06	3	24	2	23103910
Pubmed	Aggregation of embryonic stem cells induces Nanog repression and primitive endoderm differentiation.	NANOG NANOGP8	1.37e-06	3	24	2	15494369
Pubmed	The histone acetyltransferase Myst2 regulates Nanog expression, and is involved in maintaining pluripotency and self-renewal of embryonic stem cells.	NANOG NANOGP8	2.74e-06	4	24	2	25743411
Pubmed	Orphan nuclear receptor GCNF is required for the repression of pluripotency genes during retinoic acid-induced embryonic stem cell differentiation.	NANOG NANOGP8	2.74e-06	4	24	2	16166633
Pubmed	Cutting Edge: NANOG Activates Autophagy under Hypoxic Stress by Binding to BNIP3L Promoter.	NANOG NANOGP8	2.74e-06	4	24	2	28093523
Pubmed	CtBP-interacting BTB zinc finger protein (CIBZ) promotes proliferation and G1/S transition in embryonic stem cells via Nanog.	NANOG NANOGP8	2.74e-06	4	24	2	22315219
Pubmed	Loss of Pten causes tumor initiation following differentiation of murine pluripotent stem cells due to failed repression of Nanog.	NANOG NANOGP8	2.74e-06	4	24	2	21304588
Pubmed	Repression of Nanog gene transcription by Tcf3 limits embryonic stem cell self-renewal.	NANOG NANOGP8	2.74e-06	4	24	2	16894029
Pubmed	GATA-1 directly regulates Nanog in mouse embryonic stem cells.	NANOG NANOGP8	2.74e-06	4	24	2	26296469
Pubmed	Expansion of undifferentiated murine embryonic stem cells as aggregates in suspension culture bioreactors.	NANOG NANOGP8	2.74e-06	4	24	2	17518637
Pubmed	Fibroblast growth factor receptor 2 homodimerization rapidly reduces transcription of the pluripotency gene Nanog without dissociation of activating transcription factors.	NANOG NANOGP8	2.74e-06	4	24	2	22787153
Pubmed	Kruppel-like factor 4 (Klf4) prevents embryonic stem (ES) cell differentiation by regulating Nanog gene expression.	NANOG NANOGP8	2.74e-06	4	24	2	20071344
Pubmed	Cyclic mechanical strain maintains Nanog expression through PI3K/Akt signaling in mouse embryonic stem cells.	NANOG NANOGP8	2.74e-06	4	24	2	22683858
Cytoband	Ensembl 112 genes in cytogenetic band chr8p21	INTS9 HR	2.27e-03	135	24	2	chr8p21
GeneFamily	NKL subclass homeoboxes and pseudogenes	NANOG NANOGP8	1.99e-03	67	18	2	519
GeneFamily	Olfactory receptors, family 2	OR2A4 OR2A7	5.55e-03	113	18	2	149
GeneFamily	WD repeat domain containing	WDR7 WDR45B	2.75e-02	262	18	2	362
Disease	colon cancer (implicated_via_orthology)	NANOG NANOGP8	2.64e-05	11	21	2	DOID:219 (implicated_via_orthology)
Disease	Alopecia	EDNRA HR	8.19e-05	19	21	2	C0002170
Disease	Cleft Palate	EDNRA AMER1	1.51e-03	81	21	2	C0008925
Disease	Profound Mental Retardation	SRGAP3 WDR45B	4.36e-03	139	21	2	C0020796
Disease	Mental deficiency	SRGAP3 WDR45B	4.36e-03	139	21	2	C0917816
Disease	Mental Retardation, Psychosocial	SRGAP3 WDR45B	4.36e-03	139	21	2	C0025363

Protein segments in the cluster

Peptide	Gene	Start	Entry
LHLPMGPCYNLQPQA	AMER1	1026	Q5JTC6
NLVLPSNGSMHNYCP	EDNRA	56	P25101
LRMILPNPLYHCLGS	ACSF2	301	Q96CM8
MKLYCLSGHPTLPCN	INTS9	1	Q9NV88
CNPLLHTPMYFLLGN	OR11H4	61	Q8NGC9
GPSLPPDCHLLYAQM	HR	1156	O43593
YHQGCLVNPTGNLPM	NANOG	181	Q9H9S0
FHSLFNPMLNPLICS	OR2A7	276	Q96R45
FHSLFNPMLNPLICS	OR2A4	276	O95047
PQLHSPMYFFLGNLS	OR12D3	51	Q9UGF7
YPPAIPHNLSCLMNL	CSF3R	121	Q99062
ANHCPGAVMILFYLP	DCLRE1A	791	Q6PJP8
GNTSCLLHYMPQAPS	CREB3	306	O43889
YLMPGFIHLVLQPSL	DDX43	296	Q9NXZ2
CHGNTLLPQFLGMYR	PIP4K2C	176	Q8TBX8
YLPGMLHSNCPKGLL	SMG8	746	Q8ND04
YHQGCLVNPTGNLPM	NANOGP8	181	Q6NSW7
CLMNYFPLAPFNQLL	FASTKD2	506	Q9NYY8
NCYFLHPPMPALLQL	NUDT12	246	Q9BQG2
MNLLPCNPHGNGLLY	WDR45B	1	Q5MNZ6
DPYNLAICFGPTLMH	SRGAP3	651	O43295
PNYPAALMNLGAILH	TMTC2	776	Q8N394
AGCHPNPMKLLNYNP	PON3	281	Q15166
LMLPGYNQPACKLSH	WDR7	846	Q9Y4E6