Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionalcohol dehydrogenase (NAD+) activity

ADH5 ADH6 ADH1A ADH1B ADH1C

4.13e-1026315GO:0004022
GeneOntologyMolecularFunctionalcohol dehydrogenase [NAD(P)+] activity

ADH5 ADH6 ADH1A ADH1B ADH1C

8.91e-1030315GO:0018455
GeneOntologyMolecularFunctionall-trans-retinol dehydrogenase (NAD+) activity

ADH6 ADH1A ADH1B ADH1C

4.94e-0824314GO:0004745
GeneOntologyMolecularFunctionethanol binding

ADH1A ADH1B ADH1C

6.75e-086313GO:0035276
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

ADH5 ADH6 ADH1A ADH1B ADH1C

1.43e-06127315GO:0016616
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH-OH group of donors

ADH5 ADH6 ADH1A ADH1B ADH1C

2.16e-06138315GO:0016614
GeneOntologyMolecularFunctionoxidoreductase activity

ADH5 ADH6 NXN HSPBAP1 ADH1A VAT1 ADH1B ADH1C

1.63e-05766318GO:0016491
GeneOntologyMolecularFunctionzinc ion binding

ADH5 ADH6 ZNF326 MIB2 ADH1A VAT1 ADH1B ADH1C

4.81e-05891318GO:0008270
GeneOntologyMolecularFunctionNAD binding

ADH1A ADH1B ADH1C

1.96e-0473313GO:0051287
GeneOntologyMolecularFunctiontransition metal ion binding

ADH5 ADH6 ZNF326 MIB2 ADH1A VAT1 ADH1B ADH1C

3.55e-041189318GO:0046914
GeneOntologyMolecularFunctionalcohol binding

ADH1A ADH1B ADH1C

5.24e-04102313GO:0043178
GeneOntologyBiologicalProcessacetaldehyde biosynthetic process

ADH1A ADH1B ADH1C

2.78e-093303GO:0046186
GeneOntologyBiologicalProcessethanol catabolic process

ADH5 ADH1A ADH1B ADH1C

8.54e-0917304GO:0006068
GeneOntologyBiologicalProcessethanol metabolic process

ADH5 ADH1A ADH1B ADH1C

1.10e-0818304GO:0006067
GeneOntologyBiologicalProcessacetaldehyde metabolic process

ADH1A ADH1B ADH1C

2.77e-085303GO:0006117
GeneOntologyBiologicalProcessprimary alcohol catabolic process

ADH5 ADH1A ADH1B ADH1C

3.16e-0823304GO:0034310
GeneOntologyBiologicalProcessretinoid metabolic process

ADH5 ADH6 ADH1A ADH1B ADH1C

1.75e-0789305GO:0001523
GeneOntologyBiologicalProcessditerpenoid metabolic process

ADH5 ADH6 ADH1A ADH1B ADH1C

2.30e-0794305GO:0016101
GeneOntologyBiologicalProcessretinoic acid metabolic process

ADH6 ADH1A ADH1B ADH1C

3.20e-0740304GO:0042573
GeneOntologyBiologicalProcessterpenoid metabolic process

ADH5 ADH6 ADH1A ADH1B ADH1C

4.00e-07105305GO:0006721
GeneOntologyBiologicalProcessprimary alcohol metabolic process

ADH5 ADH6 ADH1A ADH1B ADH1C

4.19e-07106305GO:0034308
GeneOntologyBiologicalProcessalcohol catabolic process

ADH5 ADH1A ADH1B ADH1C

6.21e-0747304GO:0046164
GeneOntologyBiologicalProcessretinol metabolic process

ADH6 ADH1A ADH1B ADH1C

1.01e-0653304GO:0042572
GeneOntologyBiologicalProcessbehavioral response to ethanol

ADH1A ADH1B ADH1C

1.86e-0617303GO:0048149
GeneOntologyBiologicalProcessisoprenoid metabolic process

ADH5 ADH6 ADH1A ADH1B ADH1C

1.92e-06144305GO:0006720
GeneOntologyBiologicalProcessorganic hydroxy compound catabolic process

ADH5 ADH1A ADH1B ADH1C

3.69e-0673304GO:1901616
GeneOntologyBiologicalProcessaldehyde metabolic process

ADH5 ADH1A ADH1B ADH1C

1.06e-0595304GO:0006081
GeneOntologyBiologicalProcessaldehyde biosynthetic process

ADH1A ADH1B ADH1C

1.21e-0531303GO:0046184
GeneOntologyBiologicalProcessresponse to testosterone

ADH1A ADH1B ADH1C

6.19e-0553303GO:0033574
GeneOntologyBiologicalProcessresponse to ethanol

ADH6 ADH1A ADH1B ADH1C

8.37e-05161304GO:0045471
GeneOntologyBiologicalProcessolefinic compound metabolic process

ADH6 ADH1A ADH1B ADH1C

1.29e-04180304GO:0120254
GeneOntologyBiologicalProcessalcohol metabolic process

ADH5 ADH6 ADH1A ADH1B ADH1C

2.93e-04412305GO:0006066
GeneOntologyBiologicalProcesssmall molecule catabolic process

ADH5 ECH1 ADH1A ADH1B ADH1C

3.24e-04421305GO:0044282
GeneOntologyBiologicalProcessmonocarboxylic acid metabolic process

ADH5 ADH6 ECH1 ADH1A ADH1B ADH1C

5.56e-04731306GO:0032787
GeneOntologyBiologicalProcesscarboxylic acid metabolic process

ADH5 ADH6 ECH1 GNE ADH1A ADH1B ADH1C

5.78e-041035307GO:0019752
GeneOntologyBiologicalProcessoxoacid metabolic process

ADH5 ADH6 ECH1 GNE ADH1A ADH1B ADH1C

6.59e-041058307GO:0043436
GeneOntologyBiologicalProcessorganic acid metabolic process

ADH5 ADH6 ECH1 GNE ADH1A ADH1B ADH1C

6.82e-041064307GO:0006082
GeneOntologyBiologicalProcesshormone metabolic process

ADH6 ADH1A ADH1B ADH1C

7.47e-04286304GO:0042445
GeneOntologyBiologicalProcessresponse to retinoic acid

ADH1A ADH1B ADH1C

8.97e-04131303GO:0032526
GeneOntologyBiologicalProcessresponse to alcohol

ADH6 ADH1A ADH1B ADH1C

1.03e-03312304GO:0097305
GeneOntologyBiologicalProcessorganic hydroxy compound metabolic process

ADH5 ADH6 ADH1A ADH1B ADH1C

2.13e-03641305GO:1901615
GeneOntologyBiologicalProcessregulation of hormone levels

ADH6 HCFC1 ADH1A ADH1B ADH1C

2.83e-03684305GO:0010817
MousePhenoabnormal ethanol metabolism

ADH1A ADH1B ADH1C

1.01e-076253MP:0005443
MousePhenoabnormal retinol metabolism

ADH1A ADH1B ADH1C

1.76e-077253MP:0005444
MousePhenoabnormal vitamin or vitamin cofactor metabolism

ADH1A ADH1B ADH1C

2.27e-0615253MP:0013274
MousePhenoabnormal vitamin A metabolism

ADH1A ADH1B ADH1C

2.27e-0615253MP:0011233
MousePhenoabnormal vitamin metabolism

ADH1A ADH1B ADH1C

2.27e-0615253MP:0013244
MousePhenoenhanced behavioral response to alcohol

ADH1A ADH1B ADH1C

2.79e-0616253MP:0009751
MousePhenoabnormal behavioral response to alcohol

ADH1A ADH1B ADH1C

9.98e-0624253MP:0020157
MousePhenoenhanced behavioral response to addictive substance

ADH1A ADH1B ADH1C

6.38e-0544253MP:0009749
MousePhenoweight loss

HRC PRX ADH1A ADH1B ADH1C

1.97e-04312255MP:0001263
MousePhenoenhanced behavioral response to xenobiotic

ADH1A ADH1B ADH1C

2.45e-0469253MP:0009746
MousePhenoabnormal behavioral response to addictive substance

ADH1A ADH1B ADH1C

7.72e-04102253MP:0009748
DomainADH_N

ADH5 ADH6 ADH1A VAT1 ADH1B ADH1C

7.98e-1416306IPR013154
DomainADH_N

ADH5 ADH6 ADH1A VAT1 ADH1B ADH1C

7.98e-1416306PF08240
Domain-

ADH5 ADH6 ADH1A VAT1 ADH1B ADH1C

1.85e-13183063.90.180.10
DomainADH_zinc_N

ADH5 ADH6 ADH1A VAT1 ADH1B ADH1C

2.70e-1319306PF00107
DomainADH_SF_Zn-type

ADH5 ADH6 ADH1A VAT1 ADH1B ADH1C

2.70e-1319306IPR002085
DomainADH_C

ADH5 ADH6 ADH1A VAT1 ADH1B ADH1C

2.70e-1319306IPR013149
DomainADH_Zn_CS

ADH5 ADH6 ADH1A ADH1B ADH1C

4.20e-138305IPR002328
DomainADH_ZINC

ADH5 ADH6 ADH1A ADH1B ADH1C

4.20e-138305PS00059
DomainGroES-like

ADH5 ADH6 ADH1A VAT1 ADH1B ADH1C

1.33e-1224306IPR011032
DomainPKS_ER

ADH6 ADH1A VAT1 ADH1B ADH1C

3.25e-1116305IPR020843
DomainPKS_ER

ADH6 ADH1A VAT1 ADH1B ADH1C

3.25e-1116305SM00829
Domain-

ADH5 ADH6 ADH1A VAT1 ADH1B ADH1C

2.49e-071693063.40.50.720
DomainNAD(P)-bd_dom

ADH5 ADH6 ADH1A VAT1 ADH1B ADH1C

2.86e-07173306IPR016040
DomainWD40_repeat_CS

WDR1 CFAP52 STXBP5

2.27e-03164303IPR019775
DomainWD40

WDR1 CFAP52 STXBP5

8.12e-03259303PF00400
DomainWD40

WDR1 CFAP52 STXBP5

8.91e-03268303SM00320
DomainWD40_repeat

WDR1 CFAP52 STXBP5

9.28e-03272303IPR001680
DomainWD_REPEATS_1

WDR1 CFAP52 STXBP5

9.84e-03278303PS00678
DomainWD_REPEATS_2

WDR1 CFAP52 STXBP5

9.94e-03279303PS50082
DomainWD_REPEATS_REGION

WDR1 CFAP52 STXBP5

9.94e-03279303PS50294
DomainWD40_repeat_dom

WDR1 CFAP52 STXBP5

1.18e-02297303IPR017986
Domain-

WDR1 CFAP52 STXBP5

1.60e-023333032.130.10.10
DomainWD40/YVTN_repeat-like_dom

WDR1 CFAP52 STXBP5

1.62e-02335303IPR015943
DomainPDZ

MAGI1 PRX

2.14e-02141302PF00595
PathwayREACTOME_ETHANOL_OXIDATION

ADH5 ADH6 ADH1A ADH1B ADH1C

1.98e-1212195M14663
PathwayREACTOME_ETHANOL_OXIDATION

ADH5 ADH1A ADH1B ADH1C

7.73e-1011194MM15405
PathwayKEGG_FATTY_ACID_METABOLISM

ADH5 ADH6 ADH1A ADH1B ADH1C

2.07e-0942195M699
PathwayKEGG_TYROSINE_METABOLISM

ADH5 ADH6 ADH1A ADH1B ADH1C

2.07e-0942195M16743
PathwayWP_FATTY_ACID_OMEGAOXIDATION

ADH6 ADH1A ADH1B ADH1C

3.19e-0915194M39717
PathwayKEGG_GLYCOLYSIS_GLUCONEOGENESIS

ADH5 ADH6 ADH1A ADH1B ADH1C

1.55e-0862195M11521
PathwayKEGG_RETINOL_METABOLISM

ADH5 ADH6 ADH1A ADH1B ADH1C

1.82e-0864195M9488
PathwayKEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450

ADH5 ADH6 ADH1A ADH1B ADH1C

2.88e-0870195M16794
PathwayKEGG_DRUG_METABOLISM_CYTOCHROME_P450

ADH5 ADH6 ADH1A ADH1B ADH1C

3.32e-0872195M9257
PathwayREACTOME_ABACAVIR_ADME

ADH1A ADH1B ADH1C

1.16e-078193MM14869
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

ADH5 ADH6 ADH1A ADH1B ADH1C

2.12e-07104195M738
PathwayWP_FATTY_ACID_OMEGAOXIDATION

ADH1A ADH1B ADH1C

2.48e-0710193MM15833
PathwayREACTOME_RA_BIOSYNTHESIS_PATHWAY

ADH1A ADH1B ADH1C

6.66e-0628193MM15188
PathwayWP_AMINO_ACID_METABOLISM

ADH5 ADH1A ADH1B ADH1C

7.86e-0698194MM15942
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

ADH5 ADH6 ADH1A ADH1B ADH1C

8.61e-06220195M10320
PathwayWP_ETHANOL_EFFECTS_ON_HISTONE_MODIFICATIONS

ADH1A ADH1B ADH1C

9.11e-0631193M39714
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

ADH5 ADH1A ADH1B ADH1C

1.03e-05105194MM14842
PathwayWP_RETINOL_METABOLISM

ADH1A ADH1B ADH1C

2.65e-0544193MM15851
PathwayREACTOME_SIGNALING_BY_RETINOIC_ACID

ADH1A ADH1B ADH1C

3.68e-0549193MM15186
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

ADH5 ADH1A ADH1B ADH1C

1.83e-04219194MM14838
PathwayREACTOME_RA_BIOSYNTHESIS_PATHWAY

ADH1A ADH1C

3.91e-0422192M27445
PathwayWP_COMPREHENSIVE_IL17A_SIGNALING

ADH1A ADH1B ADH1C

4.09e-04110193MM16642
PathwayREACTOME_DRUG_ADME

ADH1A ADH1B ADH1C

5.15e-04119193MM15692
PathwayREACTOME_SIGNALING_BY_RETINOIC_ACID

ADH1A ADH1C

1.50e-0343192M27443
PathwayREACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS

ADH1A ADH1B ADH1C

2.02e-03191193MM15586
Pubmed

Multiple ADH genes modulate risk for drug dependence in both African- and European-Americans.

ADH5 ADH6 ADH1A ADH1B ADH1C

2.40e-15631517185388
Pubmed

Merging protein, gene and genomic data: the evolution of the MDR-ADH family.

ADH5 ADH6 ADH1A ADH1B ADH1C

2.40e-15631516121213
Pubmed

Diplotype trend regression analysis of the ADH gene cluster and the ALDH2 gene: multiple significant associations with alcohol dependence.

ADH5 ADH6 ADH1A ADH1B ADH1C

8.41e-15731516685648
Pubmed

Extended genetic effects of ADH cluster genes on the risk of alcohol dependence: from GWAS to replication.

ADH5 ADH6 ADH1A ADH1B ADH1C

8.41e-15731523456092
Pubmed

Organization of six functional mouse alcohol dehydrogenase genes on two overlapping bacterial artificial chromosomes.

ADH5 ADH6 ADH1A ADH1B ADH1C

8.41e-15731511784316
Pubmed

Association between common alcohol dehydrogenase gene (ADH) variants and schizophrenia and autism.

ADH5 ADH6 ADH1A ADH1B ADH1C

8.41e-15731523468174
Pubmed

Mouse mitochondrial aldehyde dehydrogenase isozymes: purification and molecular properties.

ADH5 ADH1A ADH1B ADH1C

5.16e-1343143996732
Pubmed

Cloning of the mouse class IV alcohol dehydrogenase (retinol dehydrogenase) cDNA and tissue-specific expression patterns of the murine ADH gene family.

ADH5 ADH1A ADH1B ADH1C

2.58e-1253147738026
Pubmed

Expression patterns of class I and class IV alcohol dehydrogenase genes in developing epithelia suggest a role for alcohol dehydrogenase in local retinoic acid synthesis.

ADH5 ADH1A ADH1B ADH1C

2.58e-1253148892527
Pubmed

Retinoic acid synthesis in mouse embryos during gastrulation and craniofacial development linked to class IV alcohol dehydrogenase gene expression.

ADH5 ADH1A ADH1B ADH1C

2.58e-1253148621625
Pubmed

Metabolic deficiencies in alcohol dehydrogenase Adh1, Adh3, and Adh4 null mutant mice. Overlapping roles of Adh1 and Adh4 in ethanol clearance and metabolism of retinol to retinoic acid.

ADH5 ADH1A ADH1B ADH1C

2.58e-12531410358022
Pubmed

Human liver alcohol dehydrogenase: purification, composition, and catalytic features.

ADH6 ADH1A ADH1B ADH1C

7.73e-1263149982
Pubmed

Excessive vitamin A toxicity in mice genetically deficient in either alcohol dehydrogenase Adh1 or Adh3.

ADH5 ADH1A ADH1B ADH1C

7.73e-12631412027900
Pubmed

Tissue- and species-specific expression patterns of class I, III, and IV Adh and Aldh 1 mRNAs in rodent embryos.

ADH5 ADH1A ADH1B ADH1C

1.80e-11731416047160
Pubmed

Association of ADH and ALDH genes with alcohol dependence in the Irish Affected Sib Pair Study of alcohol dependence (IASPSAD) sample.

ADH5 ADH1A ADH1B ADH1C

3.60e-11831418331377
Pubmed

Expression of genes for alcohol and aldehyde metabolizing enzymes in mouse oocytes and preimplantation embryos.

ADH5 ADH1A ADH1B ADH1C

2.54e-101231412128098
Pubmed

Short-term selective breeding as a tool for QTL mapping: ethanol preference drinking in mice.

ADH1A ADH1B ADH1C

6.41e-1033139145544
Pubmed

Structure of the mouse Adh-1 gene and identification of a deletion in a long alternating purine-pyrimidine sequence in the first intron of strains expressing low alcohol dehydrogenase activity.

ADH1A ADH1B ADH1C

6.41e-1033133428612
Pubmed

Cloning and sequencing of cDNA encoding the complete mouse liver alcohol dehydrogenase.

ADH1A ADH1B ADH1C

6.41e-1033133157987
Pubmed

Genetic and developmental regulation of mouse liver alcohol dehydrogenase.

ADH1A ADH1B ADH1C

6.41e-1033136816803
Pubmed

Alcohol dehydrogenase isozymes in the mouse: genetic regulation, allelic variation among inbred strains and sex differences of liver and kidney A2 isozyme activity.

ADH1A ADH1B ADH1C

6.41e-1033136756216
Pubmed

Promoters for the human alcohol dehydrogenase genes ADH1, ADH2, and ADH3: interaction of CCAAT/enhancer-binding protein with elements flanking the ADH2 TATA box.

ADH1A ADH1B ADH1C

6.41e-1033132169444
Pubmed

Recommended nomenclature for the vertebrate alcohol dehydrogenase gene family.

ADH1A ADH1B ADH1C

6.41e-10331310424757
Pubmed

Retinol/ethanol drug interaction during acute alcohol intoxication in mice involves inhibition of retinol metabolism to retinoic acid by alcohol dehydrogenase.

ADH1A ADH1B ADH1C

6.41e-10331311960985
Pubmed

Tissue-specific genetic variation in the level of mouse alcohol dehydrogenase is controlled transcriptionally in kidney and posttranscriptionally in liver.

ADH1A ADH1B ADH1C

6.41e-1033132474823
Pubmed

Beneficial effect of low ethanol intake on the cardiovascular system: possible biochemical mechanisms.

ADH1A ADH1B ADH1C

6.41e-10331317326332
Pubmed

The role of alcohol dehydrogenase in retinoic acid homeostasis and fetal alcohol syndrome.

ADH1A ADH1B ADH1C

6.41e-1033137748347
Pubmed

Chromosomal assignment of the alcohol dehydrogenase cluster locus to human chromosome 4q21-23 by in situ hybridization.

ADH1A ADH1B ADH1C

6.41e-1033132737681
Pubmed

Alcoholic fatty liver: its pathogenesis and mechanism of progression to inflammation and fibrosis.

ADH1A ADH1B ADH1C

6.41e-10331315670660
Pubmed

Regulation of human class I alcohol dehydrogenases by bile acids.

ADH1A ADH1B ADH1C

6.41e-10331323772048
Pubmed

Alcohol dehydrogenase 1 is a tubular mitophagy-dependent apoptosis inhibitor against septic acute kidney injury.

ADH1A ADH1B ADH1C

6.41e-10331337806378
Pubmed

Structure and function of a long alternating purine-pyrimidine sequence in the mouse alcohol dehydrogenase Adh-1 gene.

ADH1A ADH1B ADH1C

6.41e-1033137840644
Pubmed

A novel negative element in the promoter of the mouse alcohol dehydrogenase gene Adh-1.

ADH1A ADH1B ADH1C

6.41e-1033138486690
Pubmed

A negative regulatory element upstream from the mouse Adh-1 gene can down-regulate a heterologous promoter.

ADH1A ADH1B ADH1C

6.41e-1033138163197
Pubmed

Genetics of human alcohol and aldehyde dehydrogenases.

ADH1A ADH1B ADH1C

6.41e-1033133006456
Pubmed

Three human alcohol dehydrogenase subunits: cDNA structure and molecular and evolutionary divergence.

ADH1A ADH1B ADH1C

6.41e-1033132935875
Pubmed

ALDH expression characterizes G1-phase proliferating beta cells during pregnancy.

ADH1A ADH1B ADH1C

6.41e-10331324787690
Pubmed

Ten kilobases of 5'-flanking region confers proper regulation of the mouse alcohol dehydrogenase-1 (Adh-1) gene in kidney and adrenal of transgenic mice.

ADH1A ADH1B ADH1C

6.41e-1033138973327
Pubmed

The discovery of the microsomal ethanol oxidizing system and its physiologic and pathologic role.

ADH1A ADH1B ADH1C

6.41e-10331315554233
Pubmed

ADH1C inhibits progression of colorectal cancer through the ADH1C/PHGDH /PSAT1/serine metabolic pathway.

ADH1A ADH1B ADH1C

6.41e-10331335354963
Pubmed

Purification and characterization of mouse alcohol dehydrogenase from two inbred strains that differ in total liver enzyme activity.

ADH1A ADH1B ADH1C

6.41e-1033136370228
Pubmed

Stage and tissue-specific expression of the alcohol dehydrogenase 1 (Adh-1) gene during mouse development.

ADH1A ADH1B ADH1C

6.41e-1033138018987
Pubmed

Individual susceptibility and alcohol effects:biochemical and genetic aspects.

ADH1A ADH1B ADH1C

6.41e-10331316801720
Pubmed

Paracardial fat remodeling affects systemic metabolism through alcohol dehydrogenase 1.

ADH1A ADH1B ADH1C

6.41e-10331333586683
Pubmed

The human class I alcohol dehydrogenase gene cluster: three genes are tandemly organized in an 80-kb-long segment of the genome.

ADH1A ADH1B ADH1C

6.41e-1033132347582
Pubmed

Androgen induction of alcohol dehydrogenase in mouse kidney. Studies with a cDNA probe confirmed by nucleotide sequence analysis.

ADH1A ADH1B ADH1C

6.41e-1033133011597
Pubmed

Effects of polymorphisms in untranslated regions of the class I alcohol dehydrogenase (ADH) genes on alcohol metabolism in Japanese subjects and transcriptional activity in HepG2 cells.

ADH1A ADH1B ADH1C

2.56e-09431319618839
Pubmed

ADH1 and ADH4 alcohol/retinol dehydrogenases in the developing adrenal blastema provide evidence for embryonic retinoid endocrine function.

ADH1A ADH1B ADH1C

2.56e-0943139733106
Pubmed

Hepatic CYP2B10 is highly induced by binge ethanol and contributes to acute-on-chronic alcohol-induced liver injury.

ADH1A ADH1B ADH1C

2.56e-09431336224745
Pubmed

Overexpression of alcohol dehydrogenase exacerbates ethanol-induced contractile defect in cardiac myocytes.

ADH1A ADH1B ADH1C

2.56e-09431311893554
Pubmed

Retinoic acid and alcohol/retinol dehydrogenase in the mouse adrenal gland: a potential endocrine source of retinoic acid during development.

ADH1A ADH1B ADH1C

2.56e-0943139202249
Pubmed

Localization of class I and class IV alcohol dehydrogenases in mouse testis and epididymis: potential retinol dehydrogenases for endogenous retinoic acid synthesis.

ADH1A ADH1B ADH1C

2.56e-0943139002638
Pubmed

Genetic mapping of a possible new alcohol dehydrogenase sequence to mouse chromosome 3 at the Adh-1/Adh-3 complex.

ADH1A ADH1B ADH1C

2.56e-0943139241435
Pubmed

Genetic regulation of gene-specific mRNA by ethanol in vivo and its possible role in ethanol preference in a cross with RI lines in mice.

ADH1A ADH1B ADH1C

2.56e-0943138813054
Pubmed

Opposing actions of cellular retinol-binding protein and alcohol dehydrogenase control the balance between retinol storage and degradation.

ADH1A ADH1B ADH1C

2.56e-09431315193143
Pubmed

Metabolic pharmacokinetics of early chronic alcohol consumption mediated by liver alcohol dehydrogenases 1 and 3 in mice.

ADH1A ADH1B ADH1C

2.56e-09431329663519
Pubmed

Families of retinoid dehydrogenases regulating vitamin A function: production of visual pigment and retinoic acid.

ADH1A ADH1B ADH1C

2.56e-09431310880953
Pubmed

Distribution of class I, III and IV alcohol dehydrogenase mRNAs in the adult rat, mouse and human brain.

ADH1A ADH1B ADH1C

2.56e-09431312631290
Pubmed

Molecular analysis of mouse alcohol dehydrogenase: nucleotide sequence of the Adh-1 gene and genetic mapping of a related nucleotide sequence to chromosome 3.

ADH1A ADH1B ADH1C

2.56e-0943132893758
Pubmed

Genetic evidence that retinaldehyde dehydrogenase Raldh1 (Aldh1a1) functions downstream of alcohol dehydrogenase Adh1 in metabolism of retinol to retinoic acid.

ADH1A ADH1B ADH1C

2.56e-09431312851412
Pubmed

ADH single nucleotide polymorphism associations with alcohol metabolism in vivo.

ADH1A ADH1B ADH1C

6.40e-09531319193628
Pubmed

Distinct retinoid metabolic functions for alcohol dehydrogenase genes Adh1 and Adh4 in protection against vitamin A toxicity or deficiency revealed in double null mutant mice.

ADH1A ADH1B ADH1C

6.40e-09531311836246
Pubmed

Associations of ADH and ALDH2 gene variation with self report alcohol reactions, consumption and dependence: an integrated analysis.

ADH5 ADH1B ADH1C

6.40e-09531318996923
Pubmed

Adh1 and Adh1/4 knockout mice as possible rodent models for presymptomatic Parkinson's disease.

ADH1A ADH1B ADH1C

6.40e-09531322079585
Pubmed

Mouse alcohol dehydrogenase isozymes: products of closely localized duplicate genes exhibiting divergent kinetic properties.

ADH1A ADH1B ADH1C

6.40e-0953137026729
Pubmed

Assignment of the rat genes coding for alpha 1-antitrypsin (PI), phosphoenolpyruvate carboxykinase (PEPCK), alcohol dehydrogenase (ADH), and fructose-1,6-bisphosphatase (FDP).

ADH1A ADH1B ADH1C

6.40e-0953131316195
Pubmed

Alcohol Dehydrogenase Protects against Endoplasmic Reticulum Stress-Induced Myocardial Contractile Dysfunction via Attenuation of Oxidative Stress and Autophagy: Role of PTEN-Akt-mTOR Signaling.

ADH1A ADH1B ADH1C

1.28e-08631326807981
Pubmed

High and complementary expression patterns of alcohol and aldehyde dehydrogenases in the gastrointestinal tract: implications for Parkinson's disease.

ADH1A ADH1B ADH1C

1.28e-08631317257171
Pubmed

Genetics and ontogeny of alcohol dehydrogenase isozymes in the mouse: evidence for a cis-acting regulator gene (Adt-i) controlling C2 isozyme expression in reproductive tissues and close linkage of Adh-3 and Adt-i on chromosome 3.

ADH1A ADH1B ADH1C

1.28e-086313518534
Pubmed

Ontogeny of rdh9 (Crad3) expression: ablation causes changes in retinoid and steroid metabolizing enzymes, but RXR and androgen signaling seem normal.

ADH5 ADH1A ADH1B ADH1C

1.82e-083231417270348
Pubmed

Androgen regulation of gene expression in primary epithelial cells of the mouse kidney.

ADH1A ADH1B ADH1C

2.24e-0873138119157
Pubmed

STOmicsDB: a comprehensive database for spatial transcriptomics data sharing, analysis and visualization.

ADH1A ADH1B ADH1C

2.24e-08731337953328
Pubmed

Biochemical and genetic characterization of esterase-27 (ES-27), the major plasma cholinesterase of the house mouse (Mus musculus).

ADH1A ADH1B ADH1C

3.58e-0883132040456
Pubmed

Isolation of genomic DNA fragments corresponding to genes modulated in vivo by a transcription factor.

ADH1A ADH1B ADH1C

3.58e-0883137937138
Pubmed

Quantitative axial profiles of retinoic acid in the embryonic mouse spinal cord: 9-cis retinoic acid only detected after all-trans-retinoic acid levels are super-elevated experimentally.

ADH1A ADH1B ADH1C

5.37e-08931311747070
Pubmed

[Genetic analysis of interspecific crosses Mus musculus L. x Mus spretus Lataste: linkage of Adh-1 with Amy-1 on chromosome 3 and Es-14 with Mod-1 on chromosome 9].

ADH1A ADH1B ADH1C

5.37e-08931393520
Pubmed

The murine M-CSF gene is localized on chromosome 3.

ADH1A ADH1B ADH1C

1.05e-07113132565740
Pubmed

Genetical genomic determinants of alcohol consumption in rats and humans.

ADH5 ADH6 ADH1A ADH1B ADH1C

1.06e-0713031519874574
Pubmed

Differential gene expression in the developing mouse ureter.

ADH1A ADH1B ADH1C

1.40e-071231316459152
Pubmed

Murine Models of Acute Alcoholic Hepatitis and Their Relevance to Human Disease.

ADH1A ADH1B ADH1C

2.32e-071431326835538
Pubmed

Fim-1, Fim-2/c-fms, and Fim-3, three common integration sites of Friend murine leukemia virus in myeloblastic leukemias, map to mouse chromosomes 13, 18, and 3, respectively.

ADH1A ADH1B ADH1C

2.32e-07143132902233
Pubmed

Confirmation of quantitative trait loci for alcohol preference in mice.

ADH1A ADH1B ADH1C

2.90e-07153139726281
Pubmed

Contribution of cellular retinol-binding protein type 1 to retinol metabolism during mouse development.

ADH1A ADH1B ADH1C

3.56e-071631315765518
Pubmed

Mouse microsatellites from a flow-sorted 4:6 Robertsonian chromosome.

ADH1A ADH1B ADH1C

6.15e-07193131450512
Pubmed

Cd14, Gbp1, and Pla2g2a: three major candidate genes for experimental IBD identified by combining QTL and microarray analyses.

ADH1A ADH1B ADH1C

6.15e-071931316705022
Pubmed

Structures of three human beta alcohol dehydrogenase variants. Correlations with their functional differences.

ADH1B ADH1C

7.69e-0723128201622
Pubmed

Alcohol intake, ADH1B and ADH1C genotypes, and the risk of colorectal cancer by sex and subsite in the Netherlands Cohort Study.

ADH1B ADH1C

7.69e-07231229390059
Pubmed

ADH1B and ADH1C genotype, alcohol consumption and biomarkers of liver function: findings from a Mendelian randomization study in 58,313 European origin Danes.

ADH1B ADH1C

7.69e-07231225503943
Pubmed

[Genetic variations in alcohol dehydrogenase, drinking habits and alcoholism].

ADH1B ADH1C

7.69e-07231218761854
Pubmed

Genetic variants in or near ADH1B and ADH1C affect susceptibility to alcohol dependence in a British and Irish population.

ADH1B ADH1C

7.69e-07231224735490
Pubmed

Genetic time-series analysis identifies a major QTL for in vivo alcohol metabolism not predicted by in vitro studies of structural protein polymorphism at the ADH1B or ADH1C loci.

ADH1B ADH1C

7.69e-07231216184481
Pubmed

Alcoholism and alcohol drinking habits predicted from alcohol dehydrogenase genes.

ADH1B ADH1C

7.69e-07231217923853
Pubmed

Alcohol intake, alcohol dehydrogenase genotypes, and liver damage and disease in the Danish general population.

ADH1B ADH1C

7.69e-07231219550411
Pubmed

Association of the alcohol dehydrogenase gene polymorphism rs1789891 with gray matter brain volume, alcohol consumption, alcohol craving and relapse risk.

ADH1B ADH1C

7.69e-07231229058369
Pubmed

ADH genotype does not modify the effects of alcohol on high-density lipoprotein.

ADH1B ADH1C

7.69e-07231212658118
Pubmed

Three-dimensional structures of the three human class I alcohol dehydrogenases.

ADH1B ADH1C

7.69e-07231211274460
Pubmed

ADH1C*2 allele is associated with alcohol dependence and elevated liver enzymes in Trinidad and Tobago.

ADH1B ADH1C

7.69e-07231217134660
Pubmed

Associations of variations in alcohol dehydrogenase genes with the level of response to alcohol in non-Asians.

ADH1B ADH1C

7.69e-07231216930209
Pubmed

Alcohol intake, myocardial infarction, biochemical risk factors, and alcohol dehydrogenase genotypes.

ADH1B ADH1C

7.69e-07231220031627
Pubmed

Alcohol drinking habits, alcohol dehydrogenase genotypes and risk of acute coronary syndrome.

ADH1B ADH1C

7.69e-07231220494945
InteractionADH1B interactions

ADH1A ADH1B ADH1C

8.43e-0713303int:ADH1B
InteractionADH1A interactions

ADH1A ADH1B

2.14e-055302int:ADH1A
Cytoband4q23

ADH5 ADH6 ADH1A ADH1B ADH1C

1.54e-12203154q23
CytobandEnsembl 112 genes in cytogenetic band chr4q23

ADH5 ADH6 ADH1A ADH1B ADH1C

4.29e-1137315chr4q23
Cytoband20q11.22

ZNF341 FER1L4

2.90e-043731220q11.22
Cytoband9p13.3

GNE RUSC2

1.19e-03753129p13.3
GeneFamilyAlcohol dehydrogenases

ADH5 ADH6 ADH1A ADH1B ADH1C

4.04e-148195397
GeneFamilyWD repeat domain containing

WDR1 CFAP52 STXBP5

2.45e-03262193362
GeneFamilyPDZ domain containing

MAGI1 PRX

1.09e-021521921220
CoexpressionZHANG_UTERUS_C1_PROLIFERATIVE_STROMAL1_MGP_HIGH_CELL

TMEM119 ECH1 ADH1A VAT1 ADH1B ADH1C

1.50e-06310316MM16608
CoexpressionLEIN_CHOROID_PLEXUS_MARKERS

NXN ADH1A ADH1B ADH1C

8.16e-06109314MM1214
CoexpressionBROWNE_HCMV_INFECTION_2HR_UP

ADH1A ADH1B ADH1C

1.44e-0540313M3649
CoexpressionMCDOWELL_ACUTE_LUNG_INJURY_DN

ADH1A ADH1B ADH1C

3.18e-0552313MM693
CoexpressionIWANAGA_CARCINOGENESIS_BY_KRAS_PTEN_DN

NXN SMCHD1 ADH1A ADH1B ADH1C

7.03e-05372315MM1043
CoexpressionBURTON_ADIPOGENESIS_PEAK_AT_0HR

ADH1A ADH1B ADH1C

7.44e-0569313MM1024
CoexpressionGSE41867_NAIVE_VS_DAY30_LCMV_ARMSTRONG_MEMORY_CD8_TCELL_UP

ADH5 GNE CDC26 SMCHD1

8.64e-05199314M9502
CoexpressionGSE13306_TREG_VS_TCONV_LAMINA_PROPRIA_DN

HRC TMEM119 STXBP5 ADH1C

8.81e-05200314M3222
CoexpressionWOO_LIVER_CANCER_RECURRENCE_DN

ADH5 ADH6 ADH1B

1.07e-0478313M9911
CoexpressionCAIRO_HEPATOBLASTOMA_CLASSES_DN

ADH6 ADH1A ADH1B ADH1C

1.12e-04213314M12176
CoexpressionBROWNE_HCMV_INFECTION_16HR_DN

ADH5 ADH1A ADH1B

1.29e-0483313M19130
CoexpressionGAVIN_FOXP3_TARGETS_CLUSTER_P4

ADH1A ADH1B ADH1C

2.66e-04106313MM1216
ToppCellMesenchymal_cells-Osteoblasts|Mesenchymal_cells / Lineage and Cell class

HRC TMEM119 GNE NXN

7.65e-06183314d6b52d52fe9a7a6c798947f05420d79fe12e4662
ToppCellCOVID-19_Mild-Neu_4|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients

ECH1 CENPC STXBP5 VAT1

8.33e-06187314714851e757c71c559ee6413a3f61d6c117c79ad2
ToppCell5'-Adult-Distal_Rectal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GNE SLC17A9 STXBP5 ADH1B

1.04e-05198314db26c20321f9ab102d6484f22ddb2bde684067b1
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MINDY2 SMCHD1 PRX VAT1

1.09e-05200314b7533c571eeea0cb3678e1a57d3dc036fa8d0f49
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MINDY2 SMCHD1 PRX VAT1

1.09e-05200314bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

MINDY2 SMCHD1 PRX VAT1

1.09e-05200314432384faeade8e609154fab3d96c955a8ec868dd
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MINDY2 SMCHD1 PRX VAT1

1.09e-0520031479e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Alv_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MINDY2 SMCHD1 PRX VAT1

1.09e-0520031466f7e8ee63c828f17468e79a4b816346b33e8980
ToppCelldroplet-Liver-nan-3m-Epithelial-Hepatocyte_(Midlobular)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADH5 ECH1 ADH1A

1.68e-041553138742a4eef328c05ca9a88e499868e45073545094
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

TMEM119 ZNF326 ECH1

1.91e-04162313810881210e015c788814e4fe8d7a24c929cf2621
ToppCellAT1-AT2_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

MAGI1 MINDY2 NXN

2.17e-04169313815474855a70498a74e52f6583113c63b7267a0c
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-CD45____B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF326 RBM12B SMCHD1

2.20e-041703136210ee3bf29059e6149c047bb7e02c5f59441519
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Proliferative_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADH5 ADH1A ADH1B

2.24e-0417131359d79c3e36a4930af42ebc96f05570641b9fb864
ToppCell5'-Adult-Appendix-Epithelial-mature_enterocytic-Colonocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADH5 ECH1 ADH1C

2.28e-041723137e94ff45812f0d03829976339240f3e4ba557122
ToppCell5'-Adult-Appendix-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADH5 ECH1 ADH1C

2.28e-041723134f4d39d26c40524dbdce39334dddd0eb30c140b2
ToppCellCOVID-19-kidney-PCT-S3-2|kidney / Disease (COVID-19 only), tissue and cell type

SLC17A9 ADH1A ADH1B

2.36e-041743135aa2fb631505600f37d2b87b02def7be139dc262
ToppCellP03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TMEM119 ECH1 ADH1C

2.40e-04175313282f09bbdfa70d93b3f66591dcfb84c5ee0268c7
ToppCelldroplet-Liver-LIVER-NPC-1m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADH5 ECH1 ADH1A

2.48e-041773131b077084b78e62ead603f72c9db6ce74a3953f81
ToppCelldroplet-Liver-LIVER-NPC-1m-Epithelial-Hepatocyte_(Pericentral)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADH5 ECH1 ADH1A

2.56e-0417931310baf575f06f9a15384bcdc751446b4670acf942
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADH6 RPRML ADH1A

2.61e-041803136b1606238417490e0d9930870a7827419d1c3737
ToppCelldroplet-Liver-LIVER-NPC-1m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADH5 ECH1 ADH1A

2.65e-041813130a44781cc34535f061812d1370f748b7bbdef17b
ToppCell(2)_5-FU-(4)_COL2.3+_osteoblasts|(2)_5-FU / Stress and Cell class

TMEM119 SLC17A9 NXN

2.65e-0418131356ae86072858c156681507aecd1bc6cb0a3372d2
ToppCelldroplet-Liver-LIVER-NPC-1m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADH5 ECH1 ADH1A

2.65e-0418131348d28eafbb5f4b141deeb0bf020dfca39e7be7a5
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADH6 RPRML ADH1A

2.82e-04185313eb78614c4acf8d2ce7874d7e51e16997b76127ef
ToppCellP28-Endothelial-unknown_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RPRML PRX VAT1

2.87e-04186313dde38decf368775694bbeae38a3ff084017c34ab
ToppCellP28-Endothelial-unknown_endothelial_cell-endothelial_unknown_1|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RPRML PRX VAT1

2.87e-04186313a38f84f478798951c8798c8e90e4897c729cf630
ToppCellP28-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell_of_alveolus|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RPRML PRX VAT1

2.87e-04186313375642f353842184792a834361284d6897c728de
ToppCellP15-Endothelial-unknown_endothelial_cell-endothelial_unknown_1|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RPRML PRX VAT1

2.92e-0418731360f41b1f1b656d211b80398aa2cf0ac0cdad9372
ToppCellP15-Endothelial-unknown_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RPRML PRX VAT1

2.92e-04187313d543ddc63f864b6d0982c4ff652af174af085c4a
ToppCellP03-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell_of_alveolus|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RPRML PRX VAT1

2.92e-0418731355618ceec367c1c51ed5c447063d7fbd5c7e0808
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM119 GNE VAT1

2.96e-041883137e27e49ec1eb02fb74c86ec2ccb84751bc778b21
ToppCelldroplet-Marrow-nan-21m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM119 GNE VAT1

2.96e-041883134b14c3ad80507245564d5be96d33fd9361f67dd0
ToppCellP15-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell_of_alveolus|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RPRML PRX VAT1

2.96e-04188313c0a03e33027f52b5c25ffbc8f822128e5160ed20
ToppCellP07-Endothelial-unknown_endothelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RPRML PRX VAT1

3.01e-04189313f515a04ae1746257d4568cea13a3dd75b4b05275
ToppCellP07-Endothelial-unknown_endothelial_cell-endothelial_unknown_1|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RPRML PRX VAT1

3.01e-04189313fcfb28bd96471affc13e55aa7228f594aaa967cd
ToppCellP07-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell_of_alveolus|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RPRML PRX VAT1

3.05e-041903135d25e40bc2cca314f4265e4001a546e6d99e2a79
ToppCellCOVID-19-Endothelial_cells-Endothelial_cells_(general)|COVID-19 / group, cell type (main and fine annotations)

MAGI1 NXN PRX

3.05e-04190313812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCelldroplet-Bladder|droplet / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FER1L4 ADH1A VAT1

3.05e-04190313170484f7a6f0a0d0792bbe1bb04abad060b7188e
ToppCellP03-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TMEM119 ECH1 ADH1C

3.15e-041923132802fae55683345ff94a1ecf73b6fbee4f17481e
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RPRML PRX VAT1

3.15e-041923139a1aeac3ecf31f865a23d8ee15a82aef31779089
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADH6 RPRML ADH1A

3.15e-041923135692bd57093852d442400383850f416c497dcc7d
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RPRML PRX VAT1

3.15e-0419231353d438e35c14e7656585942b788459e6d843c555
ToppCellP03-Mesenchymal-mesenchymal_fibroblast|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TMEM119 ECH1 ADH1C

3.15e-04192313e79f2253e084a9ab9afcaf7ec42a5012ade42d36
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADH6 RPRML ADH1A

3.15e-041923130b506fb5bca54a50949932293c6f86d974a3acdd
ToppCelldroplet-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RPRML PRX VAT1

3.20e-0419331325129080f8a40b2988a5d9dfec36ff9e72c27e61
ToppCell10x5'-Liver|World / Manually curated celltypes from each tissue

ADH1A ADH1B ADH1C

3.20e-04193313d010d47d763c99e68aede59345392f2a8c77d7ac
ToppCelldroplet-Lung-nan-21m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPRML PRX VAT1

3.20e-04193313ffdcbc5caff7fd4cc2e83dd21a05d43b0593d542
ToppCelldroplet-Lung-21m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RPRML PRX VAT1

3.20e-041933133a5ad8ffad441e30a6e1bd017da7720ad57f6c57
ToppCelldroplet-Lung-nan-18m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPRML PRX VAT1

3.25e-04194313f35f03412b596b6b570b377ba1a607409d984bb1
ToppCellfacs-GAT-Fat-18m-Mesenchymal-mesenchymal_progenitor|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM119 ADH1A VAT1

3.25e-041943139709dc95fb6982b6a0467b507845d5bc17252e3e
ToppCellfacs-GAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM119 ADH1A VAT1

3.25e-0419431393b7a9065430740ec31fce4e8c14ffccb498591d
ToppCellLPS_only-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAGI1 NXN PRX

3.25e-0419431358f069efdefa0366033764446b9d6ffd4a17807e
ToppCellfacs-GAT-Fat-18m-Mesenchymal|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM119 ADH1A VAT1

3.25e-041943130d2e65b44e3f143971c2fd24c4552f042b049cfa
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAGI1 NXN PRX

3.25e-04194313bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCell10x5'-Liver-Lymphocytic_Invariant-Inducer-like-MAIT|Liver / Manually curated celltypes from each tissue

ADH1A ADH1B ADH1C

3.30e-041953136da0db2a36a34952daab87d74367b491582dedea
ToppCell10x5'-Liver-Lymphocytic_Invariant-Inducer-like|Liver / Manually curated celltypes from each tissue

ADH1A ADH1B ADH1C

3.30e-0419531337853fe760eac27ecb2fe42ebff42deca0153400
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPRML PRX VAT1

3.30e-04195313cad21edd90bf3e2fefdf5773a59cb1a664a69ddd
ToppCellP03-Mesenchymal|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TMEM119 ECH1 ADH1C

3.30e-041953136180309c6ae278b996fd98c57461cbc129c028ba
ToppCellfacs-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RPRML PRX VAT1

3.30e-041953137e0ef92059ff34e368d2324815f49b50e3ca7332
ToppCell10x5'v1-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-basophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

STXBP5 VAT1 RUSC2

3.34e-041963135bb8653af62334ded8aad48b24b64d7b54bc3cd5
ToppCellNS-moderate-d_07-13-Epithelial-Secretory|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GNE ADH1A ADH1B

3.34e-0419631347930de6b47b7bf22d8dae8b7419a9cd1d22f0ea
ToppCellCOVID-19-lung-Capillary_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

MAGI1 NXN PRX

3.34e-04196313ac28e9be288af6f00a841aea4ce4b99aed6b4505
ToppCell5'-Adult-Distal_Rectal-Epithelial-epithelial_progenitor_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GNE SLC17A9 STXBP5

3.40e-0419731319cf283537c853fa902852e7b8ac1139729a931a
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Myeloid|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

WDR1 SLC17A9 CDC26

3.40e-04197313179b56147cfb0a5f53c58615f2612b8ef68c8bb8
ToppCell5'-Adult-Distal_Rectal-Epithelial-epithelial_progenitor_cell-TA|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GNE SLC17A9 STXBP5

3.40e-04197313e14a0e8a893c72356afc5508e3531ae0b23bfe16
ToppCelldistal-mesenchymal-Vascular_Smooth_Muscle-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HRC TMEM119 ADH1B

3.45e-041983135080767ff55326b7d94fca27d398237c4a15c1ed
ToppCell5'-Adult-Distal_Rectal-Epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GNE SLC17A9 STXBP5

3.45e-041983139c0535099750698daac5d6b4d39fb19fecf4ffde
ToppCellTracheal-NucSeq-Stromal-Schwann-Schwann_Myelinating|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ECH1 PRX VAT1

3.50e-041993134e4bdcd2e8b518156d5ebd294804180acaa3566b
ToppCellLPS_IL1RA-Endothelial-Endothelial-Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MINDY2 PRX VAT1

3.55e-042003137034f57e282982c19c13ee8ab78eabaffa069e30
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SMCHD1 PRX VAT1

3.55e-04200313a1fa6bae5a688faf488d6925cd3fad725dfa916b
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MINDY2 PRX VAT1

3.55e-0420031389a6da2bdedc6b1ad0675c8753bf2b763a99af6a
ToppCellmedial-mesenchymal-Airway_Smooth_Muscle|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HRC TMEM119 ADH1B

3.55e-04200313c1d9748aaae489d26e24602a5dcbe7f5fa9a5548
ToppCellLPS_IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MINDY2 PRX VAT1

3.55e-04200313b70b7adb7c187e6253c7f0bb4c1f09c85ef7142c
ToppCellproximal-mesenchymal-Vascular_Smooth_Muscle-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HRC TMEM119 ADH1B

3.55e-042003135c0135d3cb6f7fa904e9760904dfe5f11c7e9102
ToppCellbackground-Hepatocytes|background / Sample and Cell Type and Tumor Cluster (all cells)

ADH6 ADH1A ADH1B

3.55e-04200313787d35b5c2f2ad967ae14e99496a0299ac7e72fd
ToppCellLPS_IL1RA_TNF-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SMCHD1 PRX VAT1

3.55e-04200313d01cec331be3b03cef80e9536fc531285bcf00f6
ToppCellControl_saline-Endothelial-Endothelial-Activated_Alv_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

SMCHD1 PRX VAT1

3.55e-04200313be55cef682ba87250dad97689332c8820b3a7420
ToppCellControl_saline-Endothelial-Endothelial-Alv_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

MINDY2 PRX VAT1

3.55e-04200313abf4ba5fcb54cdeada0da1a8b956a30aa47679e4
ToppCellBronchus_Control_(B.)-Stromal-TX-Fibroblasts-1|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

TMEM119 ADH1A ADH1B

3.55e-0420031316a3685c41194a0a4a772e4eee372160263480e0
ToppCellproximal-3-mesenchymal-Vascular_Smooth_Muscle|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HRC TMEM119 ADH1B

3.55e-04200313870ab11343711f64fe6d6a858fc420fe17f1636a
ToppCellmedial-mesenchymal-Airway_Smooth_Muscle-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HRC TMEM119 ADH1B

3.55e-042003136a5047018b12be3bc4b55a64d42e52e96c624003
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SMCHD1 PRX VAT1

3.55e-0420031389821a264e872ed53e08e9d3609d5cc5c314503e
ToppCellmedial-2-mesenchymal-Airway_Smooth_Muscle|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HRC TMEM119 ADH1B

3.55e-0420031316b00eacbea4d75cf814803d3fc0b82c2b8c0a9c
ToppCellproximal-mesenchymal-Vascular_Smooth_Muscle|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HRC TMEM119 ADH1B

3.55e-0420031322892afca3666e944102c231b3f10340d8391364
ComputationalNeighborhood of IGFBP1

ADH6 ADH1A ADH1B ADH1C

2.06e-0657184CAR_IGFBP1
ComputationalOxidoreductases.

ADH1A ADH1B ADH1C

5.95e-0622183MODULE_373
ComputationalGenes in the cancer module 514.

ADH1A ADH1C

1.18e-0410182MODULE_514
Drug2-NA

ADH5 ADH6 ADH1A ADH1B ADH1C

4.18e-139315CID000074128
Drug(3R,7R)-17-(6-hydroxy-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol

ADH5 ADH6 ADH1A ADH1B ADH1C

4.18e-139315CID000440672
Drughexa-2,4-dien-1-ol

ADH5 ADH6 ADH1A ADH1B ADH1C

2.62e-1212315CID000008104
Drug2-naphthaldehyde

ADH5 ADH6 ADH1A ADH1B ADH1C

4.26e-1213315CID000006201
Drugnaphthalenemethanol

ADH5 ADH6 ADH1A ADH1B ADH1C

6.62e-1214315CID000020908
Drug6-[(3R,7R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylheptanal

ADH5 ADH6 ADH1A ADH1B ADH1C

9.92e-1215315CID000440673
Drugnaphthaldehyde

ADH5 ADH6 ADH1A ADH1B ADH1C

1.44e-1116315CID000006195
Drugdhmal

ADH5 ADH6 ADH1A ADH1B ADH1C

3.87e-1029315CID000151725
DrugAC1L1AOQ

ADH5 ADH6 ADH1A ADH1B ADH1C

4.64e-1030315CID000001082
Drugwillardine

ADH5 ADH6 ADH1A ADH1B ADH1C

6.54e-1032315CID000005123
DrugDOPEG

ADH5 ADH6 ADH1A ADH1B ADH1C

1.22e-0936315CID000091528
DrugAC1L1J0I

ADH5 ADH1A ADH1B ADH1C

1.38e-0912314CID000030201
Drug4-Iodopyrazole

ADH1A ADH1B ADH1C

2.29e-093313DB02721
DrugFomepizole

ADH1A ADH1B ADH1C

9.13e-094313DB01213
Drug2-butoxyethanol

ADH5 ADH1A ADH1B ADH1C

2.93e-0824314CID000008133
Drug2,2,2-trichloroethanol

ADH5 ADH6 ADH1A ADH1B ADH1C

4.69e-0873315CID000008259
DrugEthanol

ADH1A ADH1B ADH1C

7.97e-087313DB00898
Drugbenzyl alcohol

ADH5 ADH6 ADH1A ADH1B ADH1C

8.99e-0883315CID000000244
Drugwalrycin A

ADH6 ADH1A ADH1B ADH1C

9.84e-0832314ctd:C574123
DrugN-heptylformamide

ADH1A ADH1B ADH1C

1.27e-078313CID000347402
DrugNicotinamide-Adenine-Dinucleotide

ADH5 ADH1A ADH1B ADH1C

2.48e-0740314DB01907
Drugcyclohexanol

ADH5 HCFC1 ADH1B ADH1C

4.41e-0746314CID000007966
Drug3-methylbutanal

ADH1A ADH1B ADH1C

6.48e-0713313CID000011552
DrugEGEE

ADH5 ADH1A ADH1B ADH1C

6.72e-0751314CID000008076
Drugchloral hydrate

ADH5 ADH6 ADH1A ADH1B ADH1C

8.15e-07129315CID000002707
Drugglyceraldehyde

ADH5 ADH6 ADH1A ADH1B ADH1C

1.22e-06140315CID000000751
Drugphenoxyethanol

ADH1A ADH1B ADH1C

1.26e-0616313CID000031236
Drug1H-pyrazol

ADH5 ADH6 ADH1A ADH1B ADH1C

1.27e-06141315CID000001048
DrugC x F

ADH1A ADH1B ADH1C

2.18e-0619313CID000013017
DrugPeony

ADH1A ADH1B ADH1C

2.56e-0620313CID005483934
Drug4-iodopyrazole

ADH1A ADH1B ADH1C

2.99e-0621313CID000077022
Drug3-hydroxydodecanoate

ECH1 ADH1B ADH1C

2.99e-0621313CID000094216
DrugEthylene Glycol

ADH1A ADH1B ADH1C

2.99e-0621313ctd:D019855
DrugCimetidine

ADH5 ADH1A ADH1B ADH1C

3.37e-0676314ctd:D002927
Drug4-methylpyrazole

ADH5 ADH1A ADH1B ADH1C

5.03e-0684314CID000003406
Drug4-methylpiperazine-2,6-dione

ADH1A ADH1B ADH1C

5.82e-0626313CID000124723
Drugazoxystrobin

ADH5 ADH1A ADH1B ADH1C

6.05e-0688314CID003034285
Drugfomepizole

ADH1A ADH1B ADH1C

6.54e-0627313ctd:C010238
DrugMethanol

ADH1A ADH1B ADH1C

1.00e-0531313ctd:D000432
DrugAC1L1G3W

ADH5 ADH6 ADH1A ADH1B ADH1C

1.60e-05237315CID000003514
Drug3-hydroxynonanoate

ADH1B ADH1C

1.79e-055312CID000036599
Drug3-hydroxyundecanoate

ADH1B ADH1C

1.79e-055312CID003083221
DrugN-1-methylheptylformamide

ADH1B ADH1C

1.79e-055312CID005478865
Drug2-Propanol

ADH1A ADH1B ADH1C

2.02e-0539313ctd:D019840
DrugS-[2-[3-[[4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] (2R)-2-[4-(2-methylpropyl)phenyl]propanethioate

HCFC1 ADH1B ADH1C

2.35e-0541313CID009854504
Drug1-MCP

ADH1A ADH1B ADH1C

2.35e-0541313CID000151080
Drug3-butylthiolane 1-oxide

ADH1B ADH1C

3.75e-057312CID003363251
DrugNADH

ADH5 ADH1A ADH1B ADH1C

4.23e-05144314DB00157
DrugNile red

ADH1A ADH1B ADH1C

4.29e-0550313CID000065182
Drugbeta-NADP

ADH5 ADH6 ADH1A VAT1 ADH1B ADH1C

4.49e-05490316CID000000929
Drug5-butyl-2-phenoxyphenol

ADH1B ADH1C

5.00e-058312CID005274975
DrugAC1NBLOP

ADH1B ADH1C

5.00e-058312CID004469995
Drug3-keto-LCA

ADH1B ADH1C

5.00e-058312CID000159623
Drugdisulfiram

ADH5 ADH1A ADH1B ADH1C

6.07e-05158314CID000003117
Drugcysteinylglycine

ADH1A ADH1B ADH1C

6.36e-0557313CID000065270
Drug12-oxododecanoic acid

ADH1B ADH1C

6.42e-059312CID000077563
Drug1-2H

ADH5 ADH1B ADH1C

6.70e-0558313CID000079034
DrugUDP-alpha-d-xylopyranose

ADH1A ADH1B ADH1C

7.42e-0560313CID000001165
Drugverbenone

ADH5 ADH1A

8.02e-0510312CID000029025
Drugacetaldehyde

ADH5 ADH6 ADH1A ADH1B ADH1C

8.66e-05338315CID000000177
Drugallyl alcohol

ADH1A ADH1B ADH1C

9.00e-0564313CID000007858
Drugreduced diphosphopyridine nucleotide

ADH5 ADH6 ADH1A ADH1B ADH1C

9.15e-05342315CID000000928
Drughex-2-en-1-ol

ADH5 ADH1A

9.79e-0511312CID000013577
Drugoctanol

ADH5 ADH1B ADH1C

9.87e-0566313CID000000957
Drug9-cis-retinol

ADH5 ADH6 ADH1A ADH1B ADH1C

1.12e-04357315CID000001071
DrugAC1L590V

ADH1B ADH1C

1.17e-0412312CID000172417
Drugheptadecane

ADH1B ADH1C

1.17e-0412312CID000012398
Drug11-cis-retinal

ADH5 ADH1A ADH1B ADH1C

1.21e-04189314CID000001070
DrugParoxetine maleate [64006-44-6]; Up 200; 1uM; MCF7; HT_HG-U133A

ADH6 MINDY2 PRX RUSC2

1.45e-041983143904_UP
Drug3-hydroxyoctanoate

ADH1B ADH1C

1.86e-0415312CID000026613
Drugmethanol

ADH5 ADH1A ADH1B ADH1C

2.45e-04227314CID000000887
Drugmethylthiouracil

ADH5 GNE

2.71e-0418312CID000667493
Drug3H-DA

ADH1B ADH1C

2.71e-0418312CID000026612
Drugpentadecane

ADH1B ADH1C

3.02e-0419312CID000012391
Drug3-hydroxyvalerate

ADH1B ADH1C

3.02e-0419312CID000107802
DrugPM H

ADH1B ADH1C

3.36e-0420312CID000445008
Drug1-hydroxymethylpyrene

ADH1B ADH1C

4.46e-0423312CID000104977
Drugdiamifen

ADH5 ADH1A

4.46e-0423312CID000013482
Drugscoparone

ADH1B ADH1C

5.28e-0425312CID000008417
Drugisopropanol

ADH1A ADH1B ADH1C

6.05e-04122313CID000003776
Drugandrostenol

ADH1B ADH1C

6.17e-0427312CID000101989
DrugAC1L18Y7

ADH5 ADH1A

6.17e-0427312CID000000308
DrugNADP(H

ADH5 ADH6 ADH1A ADH1B ADH1C

6.73e-04527315CID000000930
Drug3-HB

ADH1B ADH1C

7.12e-0429312CID000007420
Drugglutathione reduced

ADH5 ADH6 ADH1A ADH1B ADH1C

7.15e-04534315CID000000745
DrugAmphoterin

GNE HSPBAP1 ADH1A

8.83e-04139313CID003496889
DrugAC1L1CWO

ADH1B ADH1C

1.04e-0335312CID000002095
DrugM-NR

ADH5 ADH1A

1.04e-0335312CID003000480
Drug2-butanol

ADH1B ADH1C

1.10e-0336312CID000006568
Drug2gg8

ADH1B ADH1C

1.16e-0337312CID006914647
Drugcoenzyme 1

ADH5 ADH6 ADH1A ADH1B ADH1C

1.17e-03596315CID000000925
Drugrhein

ADH1B ADH1C

1.29e-0339312CID000010168
DrugAC1NRA3O

ADH1B ADH1C

1.36e-0340312CID005287682
Diseasealcohol use disorder measurement, longitudinal alcohol consumption measurement

ADH6 ADH1A ADH1B ADH1C

6.42e-0837314EFO_0007645, EFO_0009458
Diseasealcohol dependence measurement

ADH6 ADH1A ADH1B ADH1C

3.27e-0755314EFO_0007835
Diseasealcohol use disorder measurement

ADH5 ADH6 ADH1A ADH1B ADH1C

2.79e-06214315EFO_0009458
DiseaseAlcoholic Intoxication, Chronic

ADH5 ADH6 ADH1A ADH1B ADH1C

8.34e-06268315C0001973
DiseaseALCOHOL DEPENDENCE

ADH1B ADH1C

1.07e-055312103780
DiseaseAlcohol dependence

ADH1B ADH1C

1.07e-055312cv:C0001973
Diseasealcohol use disorder (is_implicated_in)

ADH1B ADH1C

1.27e-0416312DOID:1574 (is_implicated_in)
Diseasesex interaction measurement, cerebral amyloid angiopathy

ADH1B ADH1C

2.22e-0421312EFO_0006790, EFO_0008343
Diseasealcohol use disorder measurement, alcohol dependence

ADH1B ADH1C

2.91e-0424312EFO_0009458, MONDO_0007079
Diseaseparental emotion expression measurmement, conduct disorder

ADH1B ADH1C

3.16e-0425312EFO_0004216, EFO_0008342
DiseaseAlcoholic Intoxication

ADH1B ADH1C

5.20e-0432312C0001969
Diseasealcohol dependence

ADH1A ADH1B ADH1C

9.28e-04183313MONDO_0007079
DiseaseAlcohol Use Disorder

ADH1B ADH1C

9.83e-0444312C0001956
Diseasesubstance-related disorder

ADH1B ADH1C

1.37e-0352312MONDO_0002494
DiseaseMouth Neoplasms

ADH1B ADH1C

1.48e-0354312C0026640
DiseaseMalignant neoplasm of mouth

ADH1B ADH1C

1.48e-0354312C0153381
Diseaseecosanoids measurement

ADH1A ADH1B

1.53e-0355312EFO_0020044
Diseaseisoleucine measurement

ADH1A ADH1B

1.59e-0356312EFO_0009793
DiseaseIGF-1 measurement

ADH5 ADH1A ADH1B ADH1C

1.63e-03488314EFO_0004627
Diseasealcohol consumption measurement

ADH5 ADH6 MAGI1 ADH1A ADH1B ADH1C

1.64e-031242316EFO_0007878
DiseaseAlcohol abuse

ADH1B ADH1C

2.26e-0367312C0085762
DiseaseNon-alcoholic Fatty Liver Disease

ADH1A ADH1B

2.47e-0370312C0400966
DiseaseNonalcoholic Steatohepatitis

ADH1A ADH1B

2.47e-0370312C3241937
Diseaseunipolar depression, alcohol dependence

ADH1A ADH1B

3.05e-0378312EFO_0003761, MONDO_0007079
Diseasealcohol use disorder measurement, alcohol consumption measurement

ADH1B ADH1C

4.67e-0397312EFO_0007878, EFO_0009458
Diseasevitamin D measurement

ADH1A ADH1B ADH1C

5.19e-03336313EFO_0004631

Protein segments in the cluster

PeptideGeneStartEntry
LGHEAAGIVESVGEG

ADH1A

66

P07327
ILGHEGAGIVESIGE

ADH6

66

P28332
GHEGAGIVESVGEGV

ADH5

66

P11766
LGHEAAGIVESVGEG

ADH1B

66

P00325
LGHEAAGIVESVGEG

ADH1C

66

P00326
IEGVVEGHIIGTIGH

GPR32

206

O75388
VEVVGGSDGEGAIGL

CDC26

36

Q8NHZ8
GGVHIIGGEIGEAFI

RBM12B

31

Q8IXT5
VVFGGGNEGIVDELH

HCFC1

46

P51610
GELGVTVLGGAEHGE

MAGI1

26

Q96QZ7
QDGGGEEEGSGHLVG

FER1L4

1201

A9Z1Z3
EGEVTHVGVGHSGNI

CFAP52

576

Q8N1V2
AVHGGCIGGGVDLVT

ECH1

166

Q13011
VIVAAGAGGEEGEHV

HSPBAP1

11

Q96EW2
ITGTGIGGGIIHQHE

GNE

541

Q9Y223
NAEGSGGIVGHDEIS

CENPC

596

Q03188
QDGGEGGVGTVVELG

MIB2

26

Q96AX9
VAGVGHELGTAGDAG

MINDY2

116

Q8NBR6
GERVKGVGASEGGEE

RUSC2

1226

Q8N2Y8
GASVGTEEDGGGVGH

SMCHD1

11

A6NHR9
LNHSGLEEVDGVGGG

RPRML

6

Q8N4K4
GGGEEVDVHSLGARG

NXN

16

Q6DKJ4
TQVVGGHLGDRIGGE

SLC17A9

76

Q9BYT1
VAVHPGGDTVAIGGV

WDR1

451

O75083
EGVSGEEVFAEHGGQ

HRC

116

P23327
GIEGVKGAASGVVGE

STXBP5

1086

Q5T5C0
GGAVGAETELVVPGH

ZNF341

806

Q9BYN7
GAQVAGGELLVGEGV

PRX

1196

Q9BXM0
GMEGAGVVIAVGEGV

VAT1

111

Q99536
EGAVVAGEGQGELEG

TMEM119

241

Q4V9L6
QGVGEGGEVGVVGEV

ZNF326

536

Q5BKZ1
GGEVGVVGEVEGVGE

ZNF326

541

Q5BKZ1