Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionGTPase activator activity

PLCB1 EVI5 SRGAP2 RABGAP1 SRGAP3 SRGAP1

1.56e-05279396GO:0005096
GeneOntologyMolecularFunctionmodification-dependent protein binding

PHF2 HTATSF1 CHD1 CBX5 BRD7

4.82e-05206395GO:0140030
GeneOntologyMolecularFunctionhistone binding

PHF2 CHD1 DEK CBX5 BRD7

1.58e-04265395GO:0042393
GeneOntologyMolecularFunctionenzyme activator activity

PLCB1 EVI5 SRGAP2 RABGAP1 MNAT1 SRGAP3 SRGAP1

2.46e-04656397GO:0008047
GeneOntologyMolecularFunctionGTPase regulator activity

PLCB1 EVI5 SRGAP2 RABGAP1 SRGAP3 SRGAP1

4.16e-04507396GO:0030695
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

PLCB1 EVI5 SRGAP2 RABGAP1 SRGAP3 SRGAP1

4.16e-04507396GO:0060589
GeneOntologyMolecularFunctionmethylated histone binding

PHF2 CHD1 CBX5

6.30e-0486393GO:0035064
GeneOntologyMolecularFunctionmethylation-dependent protein binding

PHF2 CHD1 CBX5

6.74e-0488393GO:0140034
GeneOntologyMolecularFunctionmolecular adaptor activity

PHF2 HTATSF1 KMT2C YTHDC2 EIF3B OFD1 TCERG1 CBX5 BRD7

9.87e-041356399GO:0060090
GeneOntologyMolecularFunctionphosphatidylinositol phospholipase C activity

PLCB1 PLCD1

1.17e-0326392GO:0004435
GeneOntologyMolecularFunctionphospholipase C activity

PLCB1 PLCD1

1.46e-0329392GO:0004629
GeneOntologyMolecularFunctionATP hydrolysis activity

MCM7 YTHDC2 CHD1 ABCF1 HSP90AA5P

1.59e-03441395GO:0016887
GeneOntologyMolecularFunctiontranscription coactivator activity

PHF2 KMT2C TCERG1 BRD7

2.81e-03303394GO:0003713
GeneOntologyMolecularFunctionsmall GTPase binding

EVI5 SRGAP2 RABGAP1 SRGAP1

3.46e-03321394GO:0031267
GeneOntologyMolecularFunctionhelicase activity

MCM7 YTHDC2 CHD1

3.61e-03158393GO:0004386
GeneOntologyBiologicalProcessextension of a leading process involved in cell motility in cerebral cortex radial glia guided migration

SRGAP2C SRGAP2

3.67e-062402GO:0021816
GeneOntologyBiologicalProcessmodulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration

SRGAP2C SRGAP2

3.65e-055402GO:0021815
GeneOntologyBiologicalProcesschromatin organization

PHF2 HTATSF1 KMT2C CHD1 UBN1 DEK CBX5 TET1 BRD7

4.29e-05896409GO:0006325
GeneOntologyBiologicalProcesschromatin remodeling

PHF2 KMT2C CHD1 UBN1 DEK CBX5 TET1 BRD7

7.41e-05741408GO:0006338
GeneOntologyBiologicalProcesscell motility involved in cerebral cortex radial glia guided migration

SRGAP2C SRGAP2

7.65e-057402GO:0021814
GeneOntologyBiologicalProcessprotein-DNA complex organization

PHF2 HTATSF1 KMT2C CHD1 UBN1 DEK CBX5 TET1 BRD7

9.94e-05999409GO:0071824
GeneOntologyBiologicalProcessnegative regulation of cell migration

PLCB1 SRGAP2 DNAI3 SRGAP3 SRGAP1 TET1

1.45e-04419406GO:0030336
GeneOntologyBiologicalProcessnegative regulation of cell motility

PLCB1 SRGAP2 DNAI3 SRGAP3 SRGAP1 TET1

1.78e-04435406GO:2000146
GeneOntologyBiologicalProcessnegative regulation of locomotion

PLCB1 SRGAP2 DNAI3 SRGAP3 SRGAP1 TET1

2.24e-04454406GO:0040013
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

EVI5 SRGAP2C SRGAP2 RABGAP1 OFD1 DNAI3 CCDC40

2.71e-04670407GO:0120031
GeneOntologyBiologicalProcesstranscription initiation-coupled chromatin remodeling

PHF2 TET1 BRD7

2.72e-0465403GO:0045815
GeneOntologyBiologicalProcesscell projection assembly

EVI5 SRGAP2C SRGAP2 RABGAP1 OFD1 DNAI3 CCDC40

3.10e-04685407GO:0030031
GeneOntologyBiologicalProcesspositive regulation of gene expression, epigenetic

PHF2 TET1 BRD7

3.10e-0468403GO:0141137
GeneOntologyBiologicalProcessepithelial cilium movement involved in determination of left/right asymmetry

OFD1 CCDC40

3.79e-0415402GO:0060287
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

SRGAP2C SRGAP2 OFD1 SGO1 DNAI3 DEUP1 CCDC40

4.19e-04720407GO:0000226
GeneOntologyBiologicalProcesstranscription initiation at RNA polymerase II promoter

PHF2 MNAT1 TET1 BRD7

4.54e-04186404GO:0006367
GeneOntologyBiologicalProcessinositol trisphosphate metabolic process

PLCB1 PLCD1

4.90e-0417402GO:0032957
GeneOntologyBiologicalProcessinner dynein arm assembly

DNAI3 CCDC40

4.90e-0417402GO:0036159
GeneOntologyBiologicalProcesspseudopodium assembly

SRGAP2C SRGAP2

4.90e-0417402GO:0031269
GeneOntologyBiologicalProcessmeiotic cell cycle

PLCB1 MCM7 YTHDC2 CCNB1IP1 SGO1

5.52e-04350405GO:0051321
GeneOntologyBiologicalProcesspseudopodium organization

SRGAP2C SRGAP2

6.14e-0419402GO:0031268
GeneOntologyBiologicalProcessregulation of synapse assembly

SRGAP2C SRGAP2 SRGAP2B SRGAP3

6.19e-04202404GO:0051963
GeneOntologyBiologicalProcessphosphatidylinositol-mediated signaling

PLCB1 PLCD1

9.85e-0424402GO:0048015
GeneOntologyBiologicalProcessDNA-templated transcription initiation

PHF2 MNAT1 TET1 BRD7

1.02e-03231404GO:0006352
GeneOntologyBiologicalProcessaxoneme assembly

OFD1 DNAI3 CCDC40

1.23e-03109403GO:0035082
GeneOntologyCellularComponentkinetochore

PHF2 CSNK1A1L SGO1 CBX5 BRD7

2.37e-05181405GO:0000776
GeneOntologyCellularComponentcondensed chromosome

PHF2 CSNK1A1L CCNB1IP1 SGO1 CBX5 BRD7

2.41e-05307406GO:0000793
GeneOntologyCellularComponentcondensed chromosome, centromeric region

PHF2 CSNK1A1L SGO1 CBX5 BRD7

3.22e-05193405GO:0000779
GeneOntologyCellularComponentchromosomal region

PHF2 MCM7 CSNK1A1L SGO1 CBX5 BRD7

1.38e-04421406GO:0098687
GeneOntologyCellularComponentchromosome, centromeric region

PHF2 CSNK1A1L SGO1 CBX5 BRD7

1.74e-04276405GO:0000775
GeneOntologyCellularComponentnuclear protein-containing complex

HTATSF1 KMT2C MCM7 CSNK1A1L DEK RFXAP MNAT1 CBX5 TET1 BRD7

2.04e-0413774010GO:0140513
GeneOntologyCellularComponentnuclear chromosome

MCM7 CHD1 CCNB1IP1 TET1

1.38e-03254404GO:0000228
GeneOntologyCellularComponentmicrotubule organizing center

EVI5 RABGAP1 CSNK1A1L UBN1 OFD1 SGO1 DEUP1

1.62e-03919407GO:0005815
DomainFCH

SRGAP2C SRGAP2 SRGAP2B SRGAP3 SRGAP1

6.81e-1022385PF00611
DomainFCH

SRGAP2C SRGAP2 SRGAP2B SRGAP3 SRGAP1

6.81e-1022385SM00055
DomainFCH_dom

SRGAP2C SRGAP2 SRGAP2B SRGAP3 SRGAP1

8.69e-1023385IPR001060
DomainF_BAR

SRGAP2C SRGAP2 SRGAP2B SRGAP3 SRGAP1

1.37e-0925385IPR031160
DomainF_BAR

SRGAP2C SRGAP2 SRGAP2B SRGAP3 SRGAP1

1.37e-0925385PS51741
DomainsrGAP2

SRGAP2C SRGAP2 SRGAP2B

7.77e-093383IPR030252
DomainRhoGAP

SRGAP2 SRGAP3 SRGAP1

2.71e-0462383SM00324
DomainRhoGAP

SRGAP2 SRGAP3 SRGAP1

2.84e-0463383PF00620
DomainRHOGAP

SRGAP2 SRGAP3 SRGAP1

2.97e-0464383PS50238
DomainRhoGAP_dom

SRGAP2 SRGAP3 SRGAP1

2.97e-0464383IPR000198
Domain-

SRGAP2 SRGAP3 SRGAP1

2.97e-04643831.10.555.10
DomainSH3_1

SRGAP2 NEB SRGAP3 SRGAP1

3.35e-04164384PF00018
DomainPIPLC_Y_DOMAIN

PLCB1 PLCD1

4.16e-0415382PS50008
DomainPI-PLC_fam

PLCB1 PLCD1

4.16e-0415382IPR001192
DomainPLC_EF-hand-like

PLCB1 PLCD1

4.16e-0415382IPR015359
DomainPI-PLC-Y

PLCB1 PLCD1

4.16e-0415382PF00387
DomainPLipase_C_Pinositol-sp_Y

PLCB1 PLCD1

4.16e-0415382IPR001711
DomainEF-hand_like

PLCB1 PLCD1

4.16e-0415382PF09279
DomainPLCYc

PLCB1 PLCD1

4.16e-0415382SM00149
DomainPI-PLC-X

PLCB1 PLCD1

6.04e-0418382PF00388
DomainChromodomain_CS

CHD1 CBX5

6.04e-0418382IPR023779
DomainPLCXc

PLCB1 PLCD1

6.04e-0418382SM00148
DomainPIPLC_X_DOMAIN

PLCB1 PLCD1

6.74e-0419382PS50007
DomainPLipase_C_PInositol-sp_X_dom

PLCB1 PLCD1

6.74e-0419382IPR000909
DomainRho_GTPase_activation_prot

SRGAP2 SRGAP3 SRGAP1

7.57e-0488383IPR008936
DomainSH3

SRGAP2 NEB SRGAP3 SRGAP1

9.44e-04216384PS50002
DomainSH3

SRGAP2 NEB SRGAP3 SRGAP1

9.44e-04216384SM00326
DomainSH3_domain

SRGAP2 NEB SRGAP3 SRGAP1

1.01e-03220384IPR001452
DomainChromo_domain

CHD1 CBX5

1.08e-0324382IPR023780
Domain-

PLCB1 PLCD1

1.17e-03253823.20.20.190
DomainPLC-like_Pdiesterase_TIM-brl

PLCB1 PLCD1

1.17e-0325382IPR017946
DomainChromo

CHD1 CBX5

1.27e-0326382PF00385
DomainCHROMO_2

CHD1 CBX5

1.47e-0328382PS50013
DomainCHROMO_1

CHD1 CBX5

1.47e-0328382PS00598
DomainChromodomain-like

CHD1 CBX5

1.92e-0332382IPR016197
DomainCHROMO

CHD1 CBX5

2.05e-0333382SM00298
DomainChromo/shadow_dom

CHD1 CBX5

2.05e-0333382IPR000953
DomainDEAH_ATP_HELICASE

YTHDC2 CHD1

2.71e-0338382PS00690
DomainTBC

EVI5 RABGAP1

4.46e-0349382SM00164
DomainRabGAP-TBC

EVI5 RABGAP1

5.20e-0353382PF00566
DomainTBC_RABGAP

EVI5 RABGAP1

5.59e-0355382PS50086
DomainRab-GTPase-TBC_dom

EVI5 RABGAP1

5.59e-0355382IPR000195
PathwayREACTOME_INACTIVATION_OF_CDC42_AND_RAC1

SRGAP2 SRGAP3 SRGAP1

3.49e-078273M27349
PathwayPID_AURORA_B_PATHWAY

EVI5 SGO1 CBX5

5.47e-0539273M14
PathwayREACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

KMT2C DEK MNAT1 CBX5 TET1

1.07e-04254275M27131
PathwayWP_GPR40_PATHWAY

PLCB1 PLCD1

3.65e-0415272M39526
Pubmed

Inhibition of SRGAP2 function by its human-specific paralogs induces neoteny during spine maturation.

SRGAP2C SRGAP2 SRGAP2B

1.41e-09340322559944
Pubmed

Dynamic expression of the Slit-Robo GTPase activating protein genes during development of the murine nervous system.

SRGAP2 SRGAP3 SRGAP1

1.41e-09340319137586
Pubmed

Evolution of human-specific neural SRGAP2 genes by incomplete segmental duplication.

SRGAP2C SRGAP2 SRGAP2B

5.63e-09440322559943
Pubmed

SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance.

SRGAP2 SRGAP3 SRGAP1

2.81e-08640333514561
Pubmed

FNBP2 gene on human chromosome 1q32.1 encodes ARHGAP family protein with FCH, FBH, RhoGAP and SH3 domains.

SRGAP2 SRGAP3 SRGAP1

2.81e-08640312736724
Pubmed

Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway.

SRGAP2 SRGAP3 SRGAP1

2.81e-08640311672528
Pubmed

Evidence for a role of srGAP3 in the positioning of commissural axons within the ventrolateral funiculus of the mouse spinal cord.

SRGAP2 SRGAP3 SRGAP1

4.92e-08740321655271
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

HTATSF1 MCM7 CHD1 RABGAP1 EIF3B UBN1 TCERG1 DEK MNAT1 CBX5

1.63e-071014401032416067
Pubmed

TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.

PHF2 MCM7 CHD1 DEK BRD7

1.66e-0710940533554859
Pubmed

FOXA1 Directs H3K4 Monomethylation at Enhancers via Recruitment of the Methyltransferase MLL3.

PHF2 KMT2C MCM7 DEK CBX5 DEUP1

3.88e-0724840627926873
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

PHF2 CHD1 UBN1 SGO1 DEK RFXAP CBX5 BRD7

3.91e-0760840836089195
Pubmed

Jade-1S phosphorylation induced by CK1α contributes to cell cycle progression.

PHF2 ABCF1 CSNK1A1L UBN1

5.27e-075640426919559
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

HTATSF1 KMT2C MCM7 CHD1 DEK CBX5 BRD7

9.84e-0746940727634302
Pubmed

Phospholipase C isoforms are localized at the cleavage furrow during cytokinesis.

PLCB1 PLCD1

1.29e-06240217041247
Pubmed

Identification of SRGAP2 as a potential oncogene and a prognostic biomarker in hepatocellular carcinoma.

SRGAP2 SRGAP1

1.29e-06240233984363
Pubmed

The inverse F-BAR domain protein srGAP2 acts through srGAP3 to modulate neuronal differentiation and neurite outgrowth of mouse neuroblastoma cells.

SRGAP2 SRGAP3

1.29e-06240223505444
Pubmed

FF domains of CA150 bind transcription and splicing factors through multiple weak interactions.

HTATSF1 TCERG1

1.29e-06240215485897
Pubmed

Crosstalk between RNA m6A and DNA methylation regulates transposable element chromatin activation and cell fate in human pluripotent stem cells.

YTHDC2 TET1

1.29e-06240237474847
Pubmed

The human-specific paralogs SRGAP2B and SRGAP2C differentially modulate SRGAP2A-dependent synaptic development.

SRGAP2C SRGAP2B

1.29e-06240231822692
Pubmed

SRGAP2 and Its Human-Specific Paralog Co-Regulate the Development of Excitatory and Inhibitory Synapses.

SRGAP2C SRGAP2

1.29e-06240227373832
Pubmed

Slit-Robo GTPase-activating proteins are differentially expressed in murine dorsal root ganglia: modulation by peripheral nerve injury.

SRGAP3 SRGAP1

1.29e-06240222271578
Pubmed

The transcriptional transactivator Tat selectively regulates viral splicing.

HTATSF1 TCERG1

3.87e-06340219966273
Pubmed

Heterochromatin links to centromeric protection by recruiting shugoshin.

SGO1 CBX5

3.87e-06340218716626
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

PHF2 KMT2C YTHDC2 CHD1 SRGAP2 EIF3B ABCF1 TCERG1 MNAT1 BRD7

5.50e-061497401031527615
Pubmed

Phosphoinositide binding specificity among phospholipase C isozymes as determined by photo-cross-linking to novel substrate and product analogs.

PLCB1 PLCD1

7.73e-0644029188725
Pubmed

The MAT1 cyclin-dependent kinase-activating kinase (CAK) assembly/targeting factor interacts physically with the MCM7 DNA licensing factor.

MCM7 MNAT1

7.73e-06440211056214
Pubmed

Molecular cloning and characterization of a novel phospholipase C, PLC-eta.

PLCB1 PLCD1

7.73e-06440215702972
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

PHF2 YTHDC2 CHD1 EIF3B TCERG1

9.88e-0625040533536335
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

PHF2 HTATSF1 CHD1 UBN1 TCERG1 DEK CBX5 BRD7

1.10e-0595440836373674
Pubmed

Mitotic centromeric targeting of HP1 and its binding to Sgo1 are dispensable for sister-chromatid cohesion in human cells.

SGO1 CBX5

1.29e-05540221346195
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

MCM7 YTHDC2 CHD1 EIF3B ABCF1 OFD1 DEK CBX5

1.83e-05102440824711643
Pubmed

A High-Density Map for Navigating the Human Polycomb Complexome.

KMT2C MCM7 EIF3B DEK CBX5 TET1

2.05e-0549540627705803
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

HTATSF1 MCM7 CHD1 SRGAP2 EIF3B ABCF1 TCERG1 DEK NEMF

2.60e-05141540928515276
Pubmed

Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening.

SRGAP2 SRGAP3 SRGAP1

2.66e-055040319807924
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

PHF2 MCM7 YTHDC2 CHD1 EIF3B ABCF1 TCERG1 DEK NEMF

2.75e-05142540930948266
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

PHF2 CHD1 ABCF1 TCERG1 DEK CBX5

3.11e-0553340630554943
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

PHF2 HTATSF1 YTHDC2 CHD1 EIF3B HSP90AA5P DEK CBX5

4.26e-05115340829845934
Pubmed

Exogenous human immunodeficiency virus type-1 Tat protein selectively stimulates a phosphatidylinositol-specific phospholipase C nuclear pathway in the Jurkat T cell line.

PLCB1 PLCD1

4.62e-0594027589147
Pubmed

Involvement of inositol 1,4,5-trisphosphate-regulated stores of intracellular calcium in calcium dysregulation and neuron cell death caused by HIV-1 protein tat.

PLCB1 PLCD1

4.62e-05940210501179
Pubmed

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.

HTATSF1 YTHDC2 ABCF1 UBN1 CBX5

4.88e-0534940525665578
Pubmed

Expression of phospholipase C isozymes by murine B lymphocytes.

PLCB1 PLCD1

5.77e-05104022033248
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

HTATSF1 MCM7 EIF3B ABCF1 DEK CBX5

6.27e-0560540628977666
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

MCM7 CHD1 SRGAP2 TCERG1 DEK SRGAP3 SRGAP1

7.50e-0591640732203420
Pubmed

Huntingtin interacting proteins are genetic modifiers of neurodegeneration.

SRGAP2 TCERG1 SRGAP3 SRGAP1

7.78e-0519740417500595
Pubmed

The histone methyltransferase SUV420H2 and Heterochromatin Proteins HP1 interact but show different dynamic behaviours.

MCM7 CBX5

8.45e-051240219486527
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

PHF2 UBN1 OFD1 SGO1 MNAT1 CBX5

8.92e-0564540625281560
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

PHF2 HTATSF1 KMT2C UBN1 TCERG1 DEK RFXAP CBX5

9.56e-05129440830804502
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

PHF2 MCM7 CHD1 EIF3B ABCF1 TCERG1 DEK CBX5

1.09e-04131840830463901
Pubmed

Inner centromere formation requires hMis14, a trident kinetochore protein that specifically recruits HP1 to human chromosomes.

SGO1 CBX5

1.16e-041440220231385
Pubmed

Interactions of MCP1 with components of the replication machinery in mammalian cells.

MCM7 CBX5

1.16e-041440221383955
Pubmed

Epigenetic displacement of HP1 from heterochromatin by HIV-1 Vpr causes premature sister chromatid separation.

SGO1 CBX5

1.16e-041440221875947
Pubmed

Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains.

SRGAP2 TCERG1

1.16e-04144028605874
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

KMT2C SRGAP2 UBN1 SGO1 FAM81B LACTB

1.28e-0468940636543142
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PLCB1 PHF2 KMT2C SRGAP3

1.30e-0422540412168954
Pubmed

Nucleosome-interacting proteins regulated by DNA and histone methylation.

CHD1 CBX5

1.34e-041540221029866
Pubmed

Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.

MCM7 EIF3B ABCF1 TCERG1 CBX5

1.46e-0444140531239290
Pubmed

High-throughput screen for genes predominantly expressed in the ICM of mouse blastocysts by whole mount in situ hybridization.

KMT2C TCERG1 DEK

1.76e-049440316325481
Pubmed

Human transcription factor protein interaction networks.

PHF2 KMT2C EIF3B UBN1 OFD1 TCERG1 RFXAP BRD7

1.89e-04142940835140242
Pubmed

A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response.

MCM7 TCERG1

1.95e-041840229474905
Pubmed

Human immunodeficiency virus-1 glycoproteins gp120 and gp160 specifically inhibit the CD3/T cell-antigen receptor phosphoinositide transduction pathway.

PLCB1 PLCD1

1.95e-04184021979339
Pubmed

Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.

HTATSF1 CHD1 ABCF1 CBX5

1.97e-0425140428077445
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

PLCB1 YTHDC2 CSNK1A1L TCERG1 NEMF

2.06e-0447540531040226
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

PHF2 EIF3B ABCF1 TCERG1 DEK CBX5 NEMF

2.10e-04108240738697112
Pubmed

Genome-wide association with bone mass and geometry in the Framingham Heart Study.

SRGAP2C FRMD4B

2.18e-041940217903296
Pubmed

Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.

MCM7 YTHDC2 ABCF1 NEMF BRD7

2.29e-0448640530940648
Pubmed

The Polycomb Repressive Complex 1 Protein BMI1 Is Required for Constitutive Heterochromatin Formation and Silencing in Mammalian Somatic Cells.

DEK CBX5

2.67e-042140226468281
Pubmed

Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways.

EVI5 RABGAP1

2.67e-042140217562788
Pubmed

HIV-1 tat molecular diversity and induction of TNF-alpha: implications for HIV-induced neurological disease.

PLCB1 PLCD1

3.21e-04234029730685
Pubmed

The Tat protein of HIV-1 induces tumor necrosis factor-alpha production. Implications for HIV-1-associated neurological diseases.

PLCB1 PLCD1

3.21e-04234029278385
Pubmed

L3MBTL1, a histone-methylation-dependent chromatin lock.

CHD1 CBX5

3.50e-042440217540172
Pubmed

Release of calcium from inositol 1,4,5-trisphosphate receptor-regulated stores by HIV-1 Tat regulates TNF-alpha production in human macrophages.

PLCB1 PLCD1

3.50e-042440210843712
Pubmed

Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.

MCM7 CHD1 EIF3B HSP90AA5P DEK

3.66e-0453840528524877
Pubmed

Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.

CHD1 DEK CBX5

3.97e-0412440320850016
Pubmed

ATRX promotes heterochromatin formation to protect cells from G-quadruplex DNA-mediated stress.

MCM7 TCERG1

4.12e-042640234162889
Pubmed

Mechanism of HIV-1-TAT induction of interleukin-1beta from human monocytes: Involvement of the phospholipase C/protein kinase C signaling cascade.

PLCB1 PLCD1

4.45e-042740220336759
Pubmed

Identification of 14-3-3epsilon substrates from embryonic murine brain.

SRGAP2 SRGAP3 FRMD4B

4.76e-0413240316944949
Pubmed

Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.

CCDC175 ABCF1 DEK CBX5

5.01e-0432140432098917
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

MCM7 YTHDC2 EIF3B ABCF1 TCERG1 SRGAP1 LACTB

5.19e-04125740736526897
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

MCM7 RABGAP1 UBN1 SGO1 TCERG1

5.48e-0458840538580884
Pubmed

Isolation and characterization of proteins associated with histone H3 tails in vivo.

KMT2C CBX5

5.50e-043040217403666
Pubmed

Repurposing of the multiciliation gene regulatory network in fate specification of Cajal-Retzius neurons.

DEUP1 CCDC40

5.50e-043040237321213
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

CHD1 EIF3B ABCF1 CSNK1A1L DEK MNAT1

5.67e-0491040636736316
Pubmed

Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2.

PHF2 KMT2C MCM7 YTHDC2

5.75e-0433340436779763
Pubmed

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

KMT2C CSNK1A1L TET1

6.39e-0414640323892456
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

HTATSF1 YTHDC2 CHD1 SRGAP2 ABCF1 TCERG1

6.50e-0493440633916271
Pubmed

The HIV-1 Tat cellular coactivator Tat-SF1 is a general transcription elongation factor.

HTATSF1 MNAT1

6.66e-04334029765201
Pubmed

Genetic mapping of the human and mouse phospholipase C genes.

PLCB1 PLCD1

6.66e-04334028672127
Pubmed

An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance.

CSNK1A1L DEK

6.66e-043340230783098
Pubmed

WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.

YTHDC2 EIF3B ABCF1 LACTB NEMF

6.71e-0461540531048545
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

SRGAP2 RABGAP1 SRGAP3

7.05e-0415140317043677
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

MCM7 EIF3B ABCF1 TCERG1 HSP90AA5P DEK

7.06e-0494940636574265
Pubmed

Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage.

DEUP1 CCDC40

7.49e-043540237890489
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

PHF2 CBX5 BRD7

7.89e-0415740330186101
Pubmed

Signaling pathways triggered by HIV-1 Tat in human monocytes to induce TNF-alpha.

PLCB1 PLCD1

8.83e-043840212482669
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

SRGAP2 ABCF1 TCERG1 DEK CBX5

9.21e-0466040532780723
Pubmed

Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins.

YTHDC2 EIF3B OFD1

9.76e-0416940331462741
Pubmed

Characterization of the DOT1L network: implications of diverse roles for DOT1L.

CHD1 RFXAP

1.03e-034140220431927
Pubmed

Functional dissection of Rab GTPases involved in primary cilium formation.

EVI5 RABGAP1

1.13e-034340217646400
Pubmed

Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity.

EVI5 RABGAP1

1.13e-034340219077034
Pubmed

Identification of Novel Nuclear Factor of Activated T Cell (NFAT)-associated Proteins in T Cells.

CSNK1A1L DEK CBX5

1.13e-0317840327637333
InteractionH3-4 interactions

PHF2 KMT2C MCM7 CHD1 ABCF1 DEK CBX5 BRD7

2.31e-06448408int:H3-4
InteractionH3-3B interactions

MCM7 CHD1 CCNB1IP1 UBN1 CBX5

2.98e-06114405int:H3-3B
InteractionH3-3A interactions

PHF2 KMT2C CHD1 UBN1 SGO1 DEK RFXAP CBX5 BRD7

1.25e-05749409int:H3-3A
InteractionH2BC8 interactions

PHF2 CHD1 SGO1 TCERG1 DEK MNAT1 CBX5 BRD7

1.46e-05576408int:H2BC8
InteractionCIT interactions

PHF2 MCM7 YTHDC2 CHD1 EIF3B ABCF1 CSNK1A1L TCERG1 DEK CBX5 LACTB CCDC40

1.54e-0514504012int:CIT
InteractionTWIST1 interactions

PHF2 MCM7 CHD1 DEK BRD7

2.09e-05170405int:TWIST1
InteractionIRF4 interactions

KMT2C YTHDC2 OFD1 BRD7

2.40e-0585404int:IRF4
InteractionBRD3 interactions

PHF2 CHD1 ABCF1 TCERG1 DEK CBX5 BRD7

4.71e-05494407int:BRD3
InteractionH3C1 interactions

KMT2C MCM7 CHD1 NEB UBN1 DEK RFXAP CBX5 BRD7

5.36e-05901409int:H3C1
InteractionH2BC21 interactions

PHF2 MCM7 NEB DEK MNAT1 CBX5 TET1 BRD7

5.61e-05696408int:H2BC21
InteractionPYHIN1 interactions

HTATSF1 CHD1 PLCD1 ABCF1 UBN1 CBX5

6.95e-05358406int:PYHIN1
InteractionCDK8 interactions

HSP90AA5P DEK MNAT1 CBX5 SRGAP1

7.45e-05222405int:CDK8
InteractionHDAC4 interactions

PLCB1 YTHDC2 SRGAP2 EIF3B TCERG1 RFXAP CBX5 NEMF

8.96e-05744408int:HDAC4
InteractionCCDC181 interactions

ABCF1 CCNB1IP1

1.07e-048402int:CCDC181
InteractionPCNT interactions

SRGAP2 OFD1 FAM81B DEUP1 BRD7

1.10e-04241405int:PCNT
InteractionRPL5 interactions

HTATSF1 YTHDC2 EIF3B HSP90AA5P CBX5 NEMF BRD7

1.69e-04606407int:RPL5
InteractionCYTH1 interactions

OFD1 FRMD4B CCDC40

1.77e-0455403int:CYTH1
InteractionPCM1 interactions

SRGAP2 CCNB1IP1 OFD1 FAM81B SRGAP1 CCDC40

1.99e-04434406int:PCM1
InteractionLHX5 interactions

SRGAP2 SRGAP1

2.09e-0411402int:LHX5
InteractionARHGAP42 interactions

SRGAP2 DEK SRGAP1

2.29e-0460403int:ARHGAP42
InteractionH3C14 interactions

PHF2 KMT2C CBX5 BRD7

2.54e-04156404int:H3C14
InteractionSLC26A7 interactions

SRGAP2 SRGAP1

2.95e-0413402int:SLC26A7
InteractionARHGAP24 interactions

HTATSF1 MCM7 EIF3B ABCF1 DEK SRGAP3

3.65e-04486406int:ARHGAP24
CytobandEnsembl 112 genes in cytogenetic band chr13q13

CSNK1A1L RFXAP

2.35e-0382402chr13q13
CytobandEnsembl 112 genes in cytogenetic band chr14q23

CCDC175 MNAT1

5.78e-03130402chr14q23
CytobandEnsembl 112 genes in cytogenetic band chr1p22

EVI5 DNAI3

6.40e-03137402chr1p22
GeneFamilyRho GTPase activating proteins|F-BAR domain containing

SRGAP2C SRGAP2 SRGAP2B SRGAP3 SRGAP1

3.20e-11232051288
GeneFamilyRho GTPase activating proteins|BCH domain containing

SRGAP2 SRGAP3 SRGAP1

2.19e-0550203721
GeneFamilyPhospholipases|C2 domain containing phospholipases

PLCB1 PLCD1

1.97e-0419202832
GeneFamilyPhospholipases

PLCB1 PLCD1

9.75e-0442202467
GeneFamilyPHD finger proteins

PHF2 KMT2C

4.39e-039020288
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

MCM7 UBN1

1.68e-02181202694
GeneFamilyRNA binding motif containing

HTATSF1 EIF3B

2.28e-02213202725
CoexpressionGSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_2H_UP

MCM7 NEB SGO1 CBX5 SRGAP3 FRMD4B

2.87e-07183396M2993
CoexpressionHE_LIM_SUN_FETAL_LUNG_C5_LARGE_PRE_B_CELL

HTATSF1 MCM7 SRGAP2C EIF3B SRGAP2B CCNB1IP1 UBN1 SGO1 MNAT1 CBX5 BRD7

3.14e-0613633911M45782
CoexpressionRODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP

PLCB1 HTATSF1 KMT2C MCM7 SRGAP2 SRGAP2B LACTB NEMF

9.12e-06721398M10237
CoexpressionMARTIN_VIRAL_GPCR_SIGNALING_DN

UBN1 TCERG1 FRMD4B

6.40e-0552393M1330
CoexpressionGSE13547_2H_VS_12_H_ANTI_IGM_STIM_BCELL_UP

NEB OFD1 SGO1 SRGAP3

1.34e-04176394M2981
CoexpressionGSE14415_NATURAL_TREG_VS_TCONV_DN

MCM7 ABCF1 SGO1 CBX5

1.47e-04180394M2961
CoexpressionBERENJENO_TRANSFORMED_BY_RHOA_UP

MCM7 CHD1 EIF3B TCERG1 DEK CBX5

1.50e-04550396M16189
CoexpressionCHICAS_RB1_TARGETS_SENESCENT

MCM7 SRGAP2 SRGAP2B CCNB1IP1 DEK CBX5

1.74e-04565396M2125
CoexpressionTABULA_MURIS_SENIS_SPLEEN_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_CELL_AGEING

MCM7 SGO1 DEK

1.76e-0473393MM3841
CoexpressionGAUTAM_EYE_IRIS_CILIARY_BODY_CILIARY_BODY_ENDOTHELIAL_CELLS

PLCB1 KMT2C MNAT1 FRMD4B NEMF

1.77e-04356395M43609
CoexpressionBERENJENO_TRANSFORMED_BY_RHOA_UP

MCM7 CHD1 EIF3B TCERG1 DEK CBX5

1.84e-04571396MM1100
CoexpressionGRASEMANN_RETINOBLASTOMA_WITH_6P_AMPLIFICATION

ABCF1 DEK

1.94e-0414392M14308
CoexpressionGSE37416_0H_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_DN

CHD1 ABCF1 CBX5 FRMD4B

2.07e-04197394M5342
CoexpressionGSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_48H_DN

SRGAP2 EIF3B ABCF1 FRMD4B

2.11e-04198394M6089
CoexpressionGSE360_L_MAJOR_VS_T_GONDII_DC_DN

YTHDC2 UBN1 OFD1 RFXAP

2.11e-04198394M5208
CoexpressionGSE16385_ROSIGLITAZONE_IL4_VS_IL4_ALONE_STIM_MACROPHAGE_12H_UP

RABGAP1 EIF3B UBN1 OFD1

2.20e-04200394M8026
CoexpressionGSE21927_SPLEEN_C57BL6_VS_EL4_TUMOR_BALBC_MONOCYTES_DN

MCM7 EIF3B ABCF1 MNAT1

2.20e-04200394M7599
CoexpressionGSE24026_PD1_LIGATION_VS_CTRL_IN_ACT_TCELL_LINE_DN

PLCB1 MCM7 YTHDC2 EIF3B

2.20e-04200394M4538
CoexpressionGSE28237_FOLLICULAR_VS_EARLY_GC_BCELL_DN

MCM7 EIF3B TCERG1 DEK

2.20e-04200394M4885
CoexpressionGSE17721_PAM3CSK4_VS_CPG_24H_BMDC_DN

RABGAP1 ABCF1 TCERG1 LACTB

2.20e-04200394M3875
CoexpressionRODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP

EVI5 MCM7 SRGAP2 SRGAP2B CBX5 NEMF

3.52e-04644396M10501
CoexpressionZHENG_CORD_BLOOD_C7_PUTATIVE_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_1

CHD1 TCERG1 DEK

3.95e-0496393M39216
CoexpressionPUJANA_BRCA2_PCC_NETWORK

MCM7 YTHDC2 TCERG1 DEK RFXAP

4.05e-04426395M9516
CoexpressionSHEN_SMARCA2_TARGETS_UP

HTATSF1 YTHDC2 RABGAP1 DEK NEMF

4.18e-04429395M29
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1

CHD1 ABCF1 SGO1 TCERG1 DEK TET1 NEMF CCDC40 BRD7

1.36e-07469399Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

EVI5 CHD1 ABCF1 SGO1 TCERG1 DEK DEUP1 TET1 NEMF CCDC40 BRD7

4.32e-0514593911facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3

CHD1 ABCF1 SGO1 TCERG1 NEMF CCDC40 BRD7

4.57e-05532397Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

EVI5 CHD1 ABCF1 SGO1 TCERG1 DEK TET1 NEMF CCDC40 BRD7

6.68e-0512573910facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_500

KMT2C YTHDC2 CCNB1IP1 NEB OFD1 CBX5

6.92e-05387396gudmap_developingGonad_e18.5_ovary_500
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000

KMT2C YTHDC2 CCNB1IP1 NEB UBN1 OFD1 CBX5 FRMD4B

7.03e-05778398gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

ABCF1 TCERG1 DEK SRGAP1 NEMF

2.50e-04311395Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#2_top-relative-expression-ranked_500

YTHDC2 CCNB1IP1 OFD1

2.64e-0468393gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k2_500
CoexpressionAtlasdev gonad_e12.5_M_GermCellTestis_Oct_k-means-cluster#4_top-relative-expression-ranked_1000

YTHDC2 CCNB1IP1 OFD1

3.13e-0472393gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_k4_1000
ToppCellNS-critical-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CCDC175 CCDC80 FAM81B SRGAP3 CCDC40

5.10e-07176405b794275fdd757b8fa2108e3c867f23da2649146d
ToppCellCOPD-Myeloid-ncMonocyte|World / Disease state, Lineage and Cell class

PLCB1 CHD1 SRGAP2C SRGAP2 SRGAP2B

7.44e-07190405aece860b5609ad5a8fc920d685f0d0ec71bf9018
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SRGAP2C SRGAP2 SRGAP2B FRMD4B SRGAP1

7.44e-071904052d54fca50593fbd11fe13fc2bfaf937a05db776d
ToppCellControl-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

PLCB1 CHD1 SRGAP2C SRGAP2 SRGAP2B

8.03e-071934053479c01aaae7afd7e02d00e0cb21951c0106a0fd
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Myeloid-Macrophages|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SRGAP2C SRGAP2 SRGAP2B FRMD4B SRGAP1

8.24e-071944057c7091de47359760003e910cfbe63db5c99410d6
ToppCellControl-Myeloid-ncMonocyte|Control / Disease state, Lineage and Cell class

PLCB1 CHD1 SRGAP2C SRGAP2 SRGAP2B

8.45e-07195405fcb05948e7480dc53f06f3fc9b9c3fc129874edd
ToppCellCiliated_cells-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

CCDC175 DNAI3 FAM81B DEUP1

1.40e-05164404fd30c55d0d75ef8b9396435d836187168095152b
ToppCellCiliated_cells-A-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

CCDC175 DNAI3 FAM81B DEUP1

1.62e-051704048b7ef1464ea589886b575ebad5447b085cbdcdba
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1

1.69e-05172404381ae1c3c07d0a424f43455ec571653b192a946a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1

1.89e-051774044d2cdb57b427a42085c5f9affa0967b15e84dec3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1

1.94e-05178404edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1

1.98e-051794047394e77e665bf16d3733df91bb12907be460ab44
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.07e-051814045bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.07e-051814048e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCellCiliated_cells-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

CCDC80 DNAI3 FAM81B SRGAP3

2.11e-05182404e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4/8-lo-Cycling_T|bone_marrow / Manually curated celltypes from each tissue

MCM7 SGO1 DEK CBX5

2.16e-05183404a48a6313f2f144586951cece97ec31f6d72361df
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.16e-051834047c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.16e-05183404848fc6dd129150897ee339343e83c645b6e779eb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.16e-05183404eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.25e-05185404b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.25e-051854049197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCellCiliated_cells-A-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

DNAI3 FAM81B SRGAP3 DEUP1

2.25e-05185404d77ca57b02125a3a57a37f4aed20c89803b7d551
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.25e-05185404ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCellCV-Severe-3|Severe / Virus stimulation, Condition and Cluster

MCM7 SGO1 DEK FRMD4B

2.35e-0518740468cb43a73945f5e252530da25613f6b3f484b4d5
ToppCellILEUM-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CHD1 SRGAP2C SRGAP2B SRGAP3

2.35e-051874040099def970fbc828756fbf853eca2ce77b8cd342
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.40e-05188404047c4e0b03fc8334e38c48977e41d26dbe229d47
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)|Children_(3_yrs) / Lineage, Cell type, age group and donor

SRGAP2 SRGAP2B FRMD4B SRGAP1

2.50e-05190404f573fef3762a30c38cf8fa7f45df0ffbb49dc873
ToppCellIPF-Myeloid-ncMonocyte|World / Disease state, Lineage and Cell class

CHD1 SRGAP2C SRGAP2 SRGAP2B

2.50e-05190404f9c2a13c7f6460e3b348581be855b7281c8f70b5
ToppCellControl-Myeloid-cDC2|Control / Disease state, Lineage and Cell class

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.50e-051904044e481e42353d47af7991744000403af2873f6a41
ToppCellControl-Myeloid-cDC2|World / Disease state, Lineage and Cell class

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.55e-0519140411dfd8f38beb294f42710cfbd355cb089e1023c0
ToppCellLV-08._Macrophage|World / Chamber and Cluster_Paper

SRGAP2C SRGAP2 SRGAP2B FRMD4B

2.55e-05191404e7a0bc46ba9ba772636a583f3387748418e18832
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MCM7 SGO1 DEK CBX5

2.55e-0519140450854384fdaa0efa2e3227659d544ed09ac102f2
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4/8-lo-Cycling_T|bone_marrow / Manually curated celltypes from each tissue

MCM7 SGO1 DEK CBX5

2.55e-05191404210a0f1a71df2508cbfc73d6868a2122338b9a1c
ToppCellCOPD-Myeloid-cDC2|World / Disease state, Lineage and Cell class

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.55e-051914044e4887175200a57e1b041f2f131e3df774df3509
ToppCellCOPD-Myeloid-cDC2|COPD / Disease state, Lineage and Cell class

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.55e-051914042af6e4a6bd1f2193ece2131c3b7d976dd23a6966
ToppCellIPF-Myeloid-cDC2|World / Disease state, Lineage and Cell class

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.55e-051914049fda87fb6bc5b8b6c0214ec909ebbc9f3f65319b
ToppCellCOPD-Myeloid-cDC2|Myeloid / Disease state, Lineage and Cell class

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.60e-05192404984cdc2f1d93e164bc946d63f58dacb629f82eb7
ToppCellIPF-Myeloid-cDC2|IPF / Disease state, Lineage and Cell class

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.60e-05192404fe1de692fec48cba4a9bbc6eaa257260e8b4e800
ToppCellIPF-Myeloid-ncMonocyte|IPF / Disease state, Lineage and Cell class

CHD1 SRGAP2C SRGAP2 SRGAP2B

2.60e-05192404e9fb8c57d8094f70fb492909b2bec40aa5f2e5b8
ToppCellLV-08._Macrophage|LV / Chamber and Cluster_Paper

SRGAP2C SRGAP2 SRGAP2B FRMD4B

2.60e-051924047be12d580aaf2f2f1562203fcad3a44639b8c5a6
ToppCellControl-Myeloid-cDC2|Myeloid / Disease state, Lineage and Cell class

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.66e-051934044cb938c346cc32ec122d11e6b9f25db20e0f7ff6
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.66e-051934043eaa0461618582a1754400624350d269d24e750a
ToppCellCOPD-Myeloid-ncMonocyte|COPD / Disease state, Lineage and Cell class

CHD1 SRGAP2 SRGAP2B SRGAP1

2.66e-05193404936ca95995599356b794fba32bfd82d8de339365
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CCDC80 MCM7 SGO1 DEK

2.66e-05193404ecbe1bd16df547427da5e69a3017300e766c2899
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ABCF1 SGO1 DEK CBX5

2.71e-051944047a66bd7d4fc9c6db861cedd2487f241e406869d1
ToppCellILEUM-inflamed-(3)_moDC|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SRGAP2C SRGAP2B SRGAP3 SRGAP1

2.71e-05194404c9d2acab0bbcfa9a9113cf3b9f8147403f0beb43
ToppCellIPF-Myeloid-cDC2|Myeloid / Disease state, Lineage and Cell class

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.71e-05194404accf4b7b09e2048f2e47a52201e0158684dda8fe
ToppCellnucseq-Immune-Immune_Myeloid-Myeloid_Dendritic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.71e-05194404bde6830a281f7cd7fd1733e40a41ddd2673ba88e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2 SRGAP2B FRMD4B SRGAP1

2.71e-05194404c95d5c4ad0210ebd672926558cc8331e6396a854
ToppCellCOPD-Myeloid-Macrophage|World / Disease state, Lineage and Cell class

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.71e-051944047d682408e9a6239a4e47befc9376e760cc3d133a
ToppCellmetastatic_Lymph_Node-B_lymphocytes-GC_B_cells_in_the_DZ|metastatic_Lymph_Node / Location, Cell class and cell subclass

MCM7 SGO1 DEK CBX5

2.77e-051954043c5b7cce4a1c4b28fa3b657cce4148669a59e55e
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCM7 SGO1 DEK CBX5

2.77e-05195404e9c7eb0b1a2d58f69b4e839665101948bd4527b8
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCM7 SGO1 DEK CBX5

2.77e-051954047ae732f100e9a3c6062be5b877efa1ec9d5b3958
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCM7 SGO1 DEK CBX5

2.77e-05195404043e2f19d95e94cd5219e2c415f322ed340aa80f
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Myeloid|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.77e-05195404f289a44010788853d7726d4b5aa75f3c62186c08
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCM7 SGO1 DEK CBX5

2.82e-051964045ddd314d3def3776dc7da83778d41c6436ca51ac
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors|bone_marrow / Manually curated celltypes from each tissue

CCDC175 MCM7 SGO1 DEK

2.82e-051964044143dab6dce3c88c9b002c64699ab453149990e7
ToppCellSmart-seq2-thymus_(Smart-seq2)-myeloid-myeloid_macrophage-macrophage|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

YTHDC2 SRGAP2B FRMD4B SRGAP1

2.88e-05197404e567886d69c6ea8dec87019c2ebc593793cb3107
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.88e-05197404dea1d29154c585ab588e50b83c7c8de7fe24d2d4
ToppCellSmart-seq2-thymus_(Smart-seq2)-myeloid-myeloid_macrophage|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

YTHDC2 SRGAP2B FRMD4B SRGAP1

2.88e-05197404e3349a381723393cd255f202afedd0c99037939b
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCM7 SGO1 DEK CBX5

2.88e-051974049b2c67de46bd59bf56c81a0d10b84cf4a041c120
ToppCellnucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-cDC2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SRGAP2C SRGAP2 SRGAP2B SRGAP1

2.88e-05197404a902aa05e5f711bcfdd9e19749ab636b597eb116
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCM7 SGO1 DEK CBX5

2.88e-05197404f84f0ddf51208764ab56408d97035bbff562e59d
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCM7 SGO1 DEK CBX5

2.88e-05197404a0d463825b62de49466f9fa563405dda4387cfff
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells-Cycling_B_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MCM7 SGO1 DEK CBX5

2.94e-051984048bd9be3f57e7a27935c63c913e486872d52600e7
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MCM7 SGO1 DEK CBX5

2.94e-0519840406888fe2d42ac66ac12157608becd42764e0d034
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T-F_2|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MCM7 SGO1 DEK CBX5

2.94e-05198404bcfe7b6d91f2e2f145cb2660b65fd2a6c1134b86
ToppCell10x3'2.3-week_12-13-Lymphocytic_B-B_lineage-pre_pro_B_progenitor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MCM7 SGO1 DEK CBX5

3.00e-051994048e7f9312dec1e3a92b6a0ccc7baa2d46e89c11f3
ToppCellremission-T/NK_proliferative|World / disease stage, cell group and cell class

MCM7 SGO1 DEK CBX5

3.00e-05199404f305f3a454b7d2170429bad087480ccccca19acd
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MCM7 SGO1 DEK CBX5

3.00e-051994044394dcd1809f49e9bada8f5e115d5123356eae3e
ToppCell10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-pre_pro_B_progenitor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MCM7 SGO1 DEK CBX5

3.00e-0519940499778178e3ec121802db938db8c5475d19b43fec
ToppCellremission-T/NK_proliferative|remission / disease stage, cell group and cell class

MCM7 SGO1 DEK CBX5

3.00e-05199404303a5fc43a48b05b6f2060d99eef4adc36f8d4e3
ToppCell10x5'v1-week_14-16-Lymphocytic_B-B_lineage-pre_pro_B_progenitor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MCM7 SGO1 DEK CBX5

3.00e-051994048daf945fc93169b0a4fa3ef9f4a87eedd52e314a
ToppCellCOVID-19_Convalescent-Lymphoid_T/NK-T/NK_proliferative|COVID-19_Convalescent / Disease group, lineage and cell class

MCM7 SGO1 DEK CBX5

3.00e-05199404893b78c661c529db07a5fcc3124d9b3d0f270fa5
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MCM7 SGO1 DEK CBX5

3.00e-05199404c0ea391bb347b99b94b5d7f02612ede938986745
ToppCellCOVID-19_Convalescent-T/NK_proliferative|COVID-19_Convalescent / Disease condition and Cell class

MCM7 SGO1 DEK CBX5

3.00e-05199404c608d953b852b67a4e36bd63d45f0deec3eefbd9
ToppCell10x3'2.3-week_12-13-Lymphocytic_B-B_lineage|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MCM7 SGO1 DEK CBX5

3.00e-05199404fe3b7d540a644dfc6beea171c809b4d1ba4e188f
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MCM7 SGO1 DEK CBX5

3.00e-051994045b18e18ddbf4bd53aa0d574d23092cb96da7f400
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-Other_T|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MCM7 SGO1 DEK CBX5

3.00e-051994046df65f4c2f9a125e0c7c4f597fefc05a97fc8831
ToppCell356C-Lymphocytic-NK_cells-Proliferating_NK_cell|356C / Donor, Lineage, Cell class and subclass (all cells)

MCM7 SGO1 DEK CBX5

3.00e-05199404e3b69608c834bd8ce6bedde298a2763cc0d7d573
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-Other_T|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MCM7 SGO1 DEK CBX5

3.00e-05199404cb229aa3eb7b1cc47e76711b8fc18fce88a5cf08
ToppCell10x3'2.3-week_12-13-Lymphocytic_B|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MCM7 SGO1 DEK CBX5

3.00e-05199404cdee798e3586e4e7a15de598239090a85752ea1e
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MCM7 SGO1 DEK CBX5

3.00e-0519940453b3d35767889a152f1f38e8f6f0ba8f7a7690f2
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MCM7 SGO1 DEK CBX5

3.00e-0519940496af1f289552f38f2dfa181192eb3276f4c7d70b
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-cycling_ENCC/glia|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MCM7 SGO1 DEK CBX5

3.00e-051994049940f347973bf976ee23fb4b1cf1f349d96c21df
ToppCellHematolymphoid-Microglia|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SRGAP2C SRGAP2 SRGAP2B SRGAP1

3.05e-0520040421bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCell356C-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MCM7 SGO1 DEK CBX5

3.05e-052004045d11a2c0021805e78d97dc1638bf73ca1faede66
ToppCellHematolymphoid-Microglia-TYROBP----L1-3|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SRGAP2C SRGAP2 SRGAP2B SRGAP1

3.05e-05200404a20dce14f94777687aad57d6fbe3258ad376f63f
ToppCell356C-Lymphocytic-NK_cells-Proliferating_NK_cell|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

MCM7 SGO1 DEK CBX5

3.05e-0520040497e47eb69d1d4cab45256acca9589837eb7817e7
ToppCellHematolymphoid-Microglia-TYROBP--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SRGAP2C SRGAP2 SRGAP2B SRGAP1

3.05e-05200404dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCellHematolymphoid-Microglia-TYROBP---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SRGAP2C SRGAP2 SRGAP2B SRGAP1

3.05e-05200404a8646d0fca99f10827c2d2a12e584660ef7155f1
ToppCellHematolymphoid-Microglia-TYROBP-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SRGAP2C SRGAP2 SRGAP2B SRGAP1

3.05e-052004043bba5219453322198e8fdb0921d5f8c403598751
ToppCellHematolymphoid-Microglia-TYROBP|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SRGAP2C SRGAP2 SRGAP2B SRGAP1

3.05e-0520040433036d21c1c82109284473a515c4f890b33fdd5c
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MCM7 SGO1 DEK CBX5

3.05e-05200404cab374b7c56310329951c2ca44a7179ffa895b7d
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Calb1-Excitatory_Neuron.Slc17a7-Slc17a6.Calb1-Rorb-Il1rapl2_(Layer_5b)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CCDC80 CCNB1IP1 NEB

5.10e-0580403402aba070f0728ebda9db7a8fa85441533755ff4
ToppCell356C-Epithelial_cells-Epithelial-E_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SRGAP2 CCNB1IP1 TET1

2.73e-0414140331e0984f09983e83a814424f74c871c1c5a3a789
ToppCell356C-Epithelial_cells-Epithelial-E_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SRGAP2 CCNB1IP1 TET1

2.73e-04141403d7d3c3932651d90fa4f3c4e3df16f4b677faaf9f
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-2|TCGA-Colorectal / Sample_Type by Project: Shred V9

DNAI3 FAM81B CCDC40

2.79e-04142403959af19add016f21c814c28604d0177b88ebed12
ToppCellE16.5-samps|World / Age Group, Lineage, Cell class and subclass

MCM7 SGO1 CBX5

3.21e-04149403e94d075f68c1c70c89fab50b1b765b5dda650d09
ToppCell10x5'-Liver-Myeloid_Mac-Intestinal_macrophages|Liver / Manually curated celltypes from each tissue

SRGAP3 FRMD4B CCDC40

3.68e-041564039a897fc79c4fae94c5f2e9012d65297f9225e5e3
DiseaseNeurodevelopmental Disorders

PHF2 KMT2C SRGAP3

2.18e-0493373C1535926
Diseasecholesteryl ester 22:6 measurement

SRGAP2 SRGAP3

7.41e-0432372EFO_0010350
Diseasecysteine-rich with EGF-like domain protein 1 measurement

SRGAP2 SRGAP3

7.41e-0432372EFO_0021870
DiseasePolynesian Bronchiectasis

OFD1 CCDC40

8.87e-0435372C4317124
DiseaseCiliary Dyskinesia, Primary, 1, With Or Without Situs Inversus

OFD1 CCDC40

8.87e-0435372C4551906
DiseaseKartagener Syndrome

OFD1 CCDC40

8.87e-0435372C0022521
Diseaseskin microbiome measurement

SRGAP2 SRGAP3

1.10e-0339372EFO_0801228
Diseasereading and spelling ability

SRGAP2 NEB SRGAP3

1.18e-03166373EFO_0005301
Diseasefolic acid measurement

PHF2 DEUP1

1.53e-0346372EFO_0005111
DiseasePrimary Ciliary Dyskinesia

OFD1 CCDC40

1.60e-0347372C4551720
Diseaseacute myeloid leukemia (is_marker_for)

PLCB1 BRD7

1.73e-0349372DOID:9119 (is_marker_for)
Diseasecognitive behavioural therapy

NEB TCERG1

2.42e-0358372EFO_0007820
Diseaseblood lead measurement

SRGAP2 SRGAP3

3.12e-0366372EFO_0007040
Diseasebody fat percentage

SRGAP2 UBN1 SRGAP3 TET1

3.17e-03488374EFO_0007800
Diseaseschizophrenia (implicated_via_orthology)

PLCB1 SRGAP3

3.31e-0368372DOID:5419 (implicated_via_orthology)
DiseaseFEV/FEC ratio

PHF2 MCM7 SRGAP2 NEB SRGAP3 DEUP1

3.95e-031228376EFO_0004713
DiseaseAutism Spectrum Disorders

TET1 NEMF

5.12e-0385372C1510586
Diseaselung adenocarcinoma (is_marker_for)

KMT2C CBX5

5.12e-0385372DOID:3910 (is_marker_for)
Diseaseserum iron measurement

SRGAP2 SRGAP3

5.23e-0386372EFO_0006332

Protein segments in the cluster

PeptideGeneStartEntry
KEKKKLKKQMEYERQ

ABCF1

256

Q8NE71
KKDLKKYSKIFEQKD

EIF3B

721

P55884
FMKKYKKMKEGENNK

CBX5

66

P45973
KKDKDMLEDKFKSNN

BRD7

296

Q9NPI1
EKMLAKQKVSDMKYK

DEUP1

406

Q05D60
KKKVKTYQKSKEQMQ

DNAI3

841

Q8IWG1
MKKLDNYKKKDQETK

CHD1

346

O14646
KKKMKNENADKLLKS

CCDC80

551

Q76M96
EIAKIKMEAKKKYEK

OFD1

226

O75665
NMKISQKKLKKYEKE

RABGAP1

806

Q9Y3P9
KKRKKDEEEKQAMYS

KMT2C

3866

Q8NEZ4
DNTKKKMEIYQKENK

MNAT1

116

P51948
GQKSKMKKMKEKYKD

NEMF

871

O60524
KEEKAYKALKMMKEN

LACTB

231

P83111
KKKKSKEKYIDQELN

HSP90AA5P

101

Q58FG0
VKYNSKKMKKLEKEY

EVI5

401

O60447
AMTKKQKYEKISEKK

CSNK1A1L

226

Q8N752
MALKDYALEKEKVKK

MCM7

1

P33993
KADKNKDNKMSFKEL

PLCD1

151

P51178
TKMDLEKYKVQKDLK

FAM81B

426

Q96LP2
KKCKDYKKKLSMQQK

HTATSF1

231

O43719
KKKRKQDYTDAMKKL

FRMD4B

531

Q9Y2L6
YQKKKELDKLQTKMS

CCDC175

256

P0C221
EKGSVQYKKKEEMLK

DEK

136

P35659
AYKKSIMKEEEKNEK

CCDC40

536

Q4G0X9
KKIEKMKEKRQAKYS

SRGAP1

216

Q7Z6B7
KQKDCKMKLKEFVDY

PHF2

166

O75151
MSKYKENKSENKKTV

SGO1

306

Q5FBB7
KKIEKMKEKHQAKYT

SRGAP2C

226

P0DJJ0
KKIEKMKEKRQAKYT

SRGAP2B

226

P0DMP2
RNKMYKDKYKKKKSD

RFXAP

166

O00287
IKFEAKEAKNKKMKA

TET1

2066

Q8NFU7
KEAKNKKMKASEQKD

TET1

2071

Q8NFU7
MKKVLEEYKKKFSDI

CCNB1IP1

146

Q9NPC3
KKIEKMKEKRQAKYS

SRGAP3

216

O43295
KKNKIMQAKEDFKKM

TCERG1

721

O14776
KKIEKMKEKRQAKYT

SRGAP2

226

O75044
KLQKKHYKEMKDLVK

PLCB1

921

Q9NQ66
NKEMLKYKKEKQQEE

YTHDC2

391

Q9H6S0
KEMLKKFQKEKEAQK

UBN1

246

Q9NPG3
EKNKKAMEIISEKKY

NEB

1946

P20929
VSEKKYKIQYEKMKD

NEB

5226

P20929