Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionzinc ion sequestering activity

S100A7 S100A7A

4.79e-054572GO:0140486
GeneOntologyMolecularFunctionmetal ion sequestering activity

S100A7 S100A7A

2.22e-048572GO:0140487
GeneOntologyBiologicalProcessmodulation of inhibitory postsynaptic potential

NTSR1 GRIN2B CHRNA2

3.88e-0612553GO:0098828
GeneOntologyBiologicalProcessendocardial cushion development

BMPR1A NFATC1 SNAI2 SNAI1

1.72e-0558554GO:0003197
GeneOntologyBiologicalProcessheart valve morphogenesis

BMPR1A NFATC1 SNAI2 SNAI1

2.40e-0563554GO:0003179
GeneOntologyBiologicalProcessinhibitory postsynaptic potential

NTSR1 GRIN2B CHRNA2

5.01e-0527553GO:0060080
GeneOntologyBiologicalProcessheart valve development

BMPR1A NFATC1 SNAI2 SNAI1

5.57e-0578554GO:0003170
GeneOntologyBiologicalProcessnegative regulation of vitamin D biosynthetic process

SNAI2 SNAI1

6.95e-055552GO:0010957
GeneOntologyBiologicalProcessendocardial cushion formation

BMPR1A SNAI2 SNAI1

8.42e-0532553GO:0003272
GeneOntologyBiologicalProcessregulation of vitamin D biosynthetic process

SNAI2 SNAI1

1.45e-047552GO:0060556
GeneOntologyBiologicalProcessaortic valve morphogenesis

NFATC1 SNAI2 SNAI1

1.53e-0439553GO:0003180
GeneOntologyBiologicalProcessregulation of DNA damage response, signal transduction by p53 class mediator

NPM1 SNAI2 SNAI1

1.65e-0440553GO:0043516
GeneOntologyBiologicalProcessendocardial cushion morphogenesis

BMPR1A SNAI2 SNAI1

2.20e-0444553GO:0003203
GeneOntologyBiologicalProcessaortic valve development

NFATC1 SNAI2 SNAI1

2.51e-0446553GO:0003176
GeneOntologyBiologicalProcessmembraneless organelle assembly

NPM1 HAUS6 NEK6 MAPT STARD9 POC1B TNS3

2.57e-04475557GO:0140694
GeneOntologyBiologicalProcessvitamin D biosynthetic process

SNAI2 SNAI1

3.10e-0410552GO:0042368
GeneOntologyBiologicalProcesspositive regulation of inhibitory postsynaptic potential

NTSR1 GRIN2B

3.10e-0410552GO:0097151
GeneOntologyBiologicalProcessnegative regulation of vitamin metabolic process

SNAI2 SNAI1

3.10e-0410552GO:0046137
GeneOntologyBiologicalProcesssemi-lunar valve development

NFATC1 SNAI2 SNAI1

3.22e-0450553GO:1905314
GeneOntologyBiologicalProcesscartilage morphogenesis

SNAI2 SNAI1

4.53e-0412552GO:0060536
GeneOntologyCellularComponentmicrotubule organizing center

CCDC14 NPM1 HAUS6 NDRG1 NEK6 STARD9 POLR3H ENTR1 POC1B LRP1 DYNC1I2

2.26e-059195511GO:0005815
GeneOntologyCellularComponentcentrosome

CCDC14 NPM1 HAUS6 NDRG1 NEK6 POLR3H ENTR1 POC1B DYNC1I2

1.66e-04770559GO:0005813
GeneOntologyCellularComponentouter dynein arm

DNAI2 DYNC1I2

4.41e-0412552GO:0036157
GeneOntologyCellularComponentmicrotubule

HAUS6 NDRG1 NEK6 CFAP52 MAPT DNAI2 DYNC1I2

4.74e-04533557GO:0005874
DomainWD40

AAMP DMXL2 CFAP52 TBL1Y WDR6 POC1B DNAI2 DYNC1I2

6.34e-07259538PF00400
DomainWD40

AAMP DMXL2 CFAP52 TBL1Y WDR6 POC1B DNAI2 DYNC1I2

8.21e-07268538SM00320
DomainWD40_repeat

AAMP DMXL2 CFAP52 TBL1Y WDR6 POC1B DNAI2 DYNC1I2

9.18e-07272538IPR001680
DomainWD_REPEATS_1

AAMP DMXL2 CFAP52 TBL1Y WDR6 POC1B DNAI2 DYNC1I2

1.08e-06278538PS00678
DomainWD_REPEATS_2

AAMP DMXL2 CFAP52 TBL1Y WDR6 POC1B DNAI2 DYNC1I2

1.11e-06279538PS50082
DomainWD_REPEATS_REGION

AAMP DMXL2 CFAP52 TBL1Y WDR6 POC1B DNAI2 DYNC1I2

1.11e-06279538PS50294
DomainWD40_repeat_dom

AAMP DMXL2 CFAP52 TBL1Y WDR6 POC1B DNAI2 DYNC1I2

1.77e-06297538IPR017986
Domain-

AAMP DMXL2 CFAP52 TBL1Y WDR6 POC1B DNAI2 DYNC1I2

4.14e-063335382.130.10.10
DomainWD40/YVTN_repeat-like_dom

AAMP DMXL2 CFAP52 TBL1Y WDR6 POC1B DNAI2 DYNC1I2

4.32e-06335538IPR015943
DomainS100A7

S100A7 S100A7A

7.90e-062532IPR028477
DomainQuinoprotein_ADH-like_supfam

AAMP DMXL2 WDR6

4.57e-0453533IPR011047
DomainWD40_repeat_CS

AAMP CFAP52 TBL1Y POC1B

1.20e-03164534IPR019775
DomainS100_CABP

S100A7 S100A7A

2.65e-0327532PS00303
DomainS_100

S100A7 S100A7A

2.65e-0327532PF01023
DomainS100_Ca-bd_sub

S100A7 S100A7A

2.85e-0328532IPR013787
DomainS100/CaBP-9k_CS

S100A7 S100A7A

2.85e-0328532IPR001751
DomainS_100

S100A7 S100A7A

2.85e-0328532SM01394
Domain6-blade_b-propeller_TolB-like

WDR6 LRP1

7.55e-0346532IPR011042
Pubmed

Endocardial to myocardial notch-wnt-bmp axis regulates early heart valve development.

BMPR1A NFATC1 SNAI2 SNAI1

8.58e-082558423560082
Pubmed

RERE deficiency leads to decreased expression of GATA4 and the development of ventricular septal defects.

NFATC1 SNAI2 SNAI1

9.58e-071258330061196
Pubmed

Nfatc1 coordinates valve endocardial cell lineage development required for heart valve formation.

NFATC1 SNAI2 SNAI1

1.58e-061458321597012
Pubmed

Endoglin is dispensable for angiogenesis, but required for endocardial cushion formation in the midgestation mouse embryo.

NFATC1 SNAI2 SNAI1

1.58e-061458319703439
Pubmed

NFATc1 promotes epithelial-mesenchymal transition and facilitates colorectal cancer metastasis by targeting SNAI1.

NFATC1 SNAI1

2.73e-06258234597678
Pubmed

Identification and analysis of two snail genes in the pufferfish (Fugu rubripes) and mapping of human SNA to 20q.

SNAI2 SNAI1

2.73e-06258210773451
Pubmed

Tumor-induced upregulation of Twist, Snail, and Slug represses the activity of the human VE-cadherin promoter.

SNAI2 SNAI1

2.73e-06258219046938
Pubmed

Impact of Selected Signaling Proteins on SNAIL 1 and SNAIL 2 Expression in Ovarian Cancer Cell Lines in Relation to Cells' Cisplatin Resistance and EMT Markers Level.

SNAI2 SNAI1

2.73e-06258233478150
Pubmed

LRP1 is critical for the surface distribution and internalization of the NR2B NMDA receptor subtype.

LRP1 GRIN2B

2.73e-06258223866919
Pubmed

Conserved and divergent roles for members of the Snail family of transcription factors in the chick and mouse embryo.

SNAI2 SNAI1

2.73e-0625829671584
Pubmed

SNAI1 and SNAI2 are asymmetrically expressed at the 2-cell stage and become segregated to the TE in the mouse blastocyst.

SNAI2 SNAI1

2.73e-06258220046880
Pubmed

Snail and Slug, key regulators of TGF-β-induced EMT, are sufficient for the induction of single-cell invasion.

SNAI2 SNAI1

2.73e-06258223618854
Pubmed

Distinct EMT programs control normal mammary stem cells and tumour-initiating cells.

SNAI2 SNAI1

2.73e-06258226331542
Pubmed

Hepatic Snai1 and Snai2 promote liver regeneration and suppress liver fibrosis in mice.

SNAI2 SNAI1

2.73e-06258238451818
Pubmed

Expression and localization of transcription factors SNAIL and SLUG in mouse ovaries and pre-implantation embryos.

SNAI2 SNAI1

2.73e-06258225092544
Pubmed

'Snail factors in testicular germ cell tumours and their regulation by the BMP4 signalling pathway'.

SNAI2 SNAI1

2.73e-06258232441446
Pubmed

The SNAI1 and SNAI2 proteins occupy their own and each other's promoter during chondrogenesis.

SNAI2 SNAI1

2.73e-06258223665016
Pubmed

Modularity and reshuffling of Snail and Slug expression during vertebrate evolution.

SNAI2 SNAI1

2.73e-06258212482931
Pubmed

Snail family transcription factors are implicated in thyroid carcinogenesis.

SNAI2 SNAI1

2.73e-06258217724139
Pubmed

Snai1 and Snai2 collaborate on tumor growth and metastasis properties of mouse skin carcinoma cell lines.

SNAI2 SNAI1

2.73e-06258218408755
Pubmed

SNAIL Transctiption factor in prostate cancer cells promotes neurite outgrowth.

SNAI2 SNAI1

2.73e-06258233132158
Pubmed

Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress.

SNAI2 SNAI1

2.73e-06258215314165
Pubmed

Slug and Snail have differential effects in directing colonic epithelial wound healing and partially mediate the restitutive effects of butyrate.

SNAI2 SNAI1

2.73e-06258231393789
Pubmed

Snail is an independent prognostic predictor for progression and patient survival of gastric cancer.

SNAI2 SNAI1

2.73e-06258222471696
Pubmed

Risk Variants in or Near ZBTB40 AND NFATC1 Increase the Risk of Both IBD and Adverse Bone Health Outcomes Highlighting Common Genetic Underpinnings Across Both Diseases.

NFATC1 ZBTB40

2.73e-06258236680554
Pubmed

Regulation of tau internalization, degradation, and seeding by LRP1 reveals multiple pathways for tau catabolism.

MAPT LRP1

2.73e-06258233930462
Pubmed

Snail2 cooperates with Snail1 in the repression of vitamin D receptor in colon cancer.

SNAI2 SNAI1

2.73e-06258219502595
Pubmed

[SNAI1 and SNAI2 - transcriptional master-regulators of epithelial-mesenchimal transition].

SNAI2 SNAI1

2.73e-06258226571812
Pubmed

The transcriptional repressor Snail promotes mammary tumor recurrence.

SNAI2 SNAI1

2.73e-06258216169465
Pubmed

Expression of Snail and Slug in renal cell carcinoma: E-cadherin repressor Snail is associated with cancer invasion and prognosis.

SNAI2 SNAI1

2.73e-06258221808237
Pubmed

Erg is a crucial regulator of endocardial-mesenchymal transformation during cardiac valve morphogenesis.

NFATC1 SNAI2 SNAI1

5.73e-062158322932696
Pubmed

Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development.

BMPR1A NFATC1 SNAI2 SNAI1

6.58e-067258437702066
Pubmed

Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning.

BMPR1A NFATC1 SNAI1

7.61e-062358316314491
Pubmed

The transcription factors Snail and Slug activate the transforming growth factor-beta signaling pathway in breast cancer.

SNAI2 SNAI1

8.19e-06358222028892
Pubmed

Interaction of endogenous tau protein with synaptic proteins is regulated by N-methyl-D-aspartate receptor-dependent tau phosphorylation.

MAPT GRIN2B

8.19e-06358222833681
Pubmed

The mouse S100A15 ortholog parallels genomic organization, structure, gene expression, and protein-processing pattern of the human S100A7/A15 subfamily during epidermal maturation.

S100A7 S100A7A

8.19e-06358216528363
Pubmed

Inhibition of CK2 mitigates Alzheimer's tau pathology by preventing NR2B synaptic mislocalization.

MAPT GRIN2B

8.19e-06358235246269
Pubmed

Genetic profiling of epithelial cells expressing E-cadherin repressors reveals a distinct role for Snail, Slug, and E47 factors in epithelial-mesenchymal transition.

SNAI2 SNAI1

8.19e-06358217018611
Pubmed

Immunohistochemical study of correlation between histologic subtype and expression of epithelial-mesenchymal transition-related proteins in synovial sarcomas.

SNAI2 SNAI1

8.19e-06358221809991
Pubmed

Depletion of Progranulin Reduces GluN2B-Containing NMDA Receptor Density, Tau Phosphorylation, and Dendritic Arborization in Mouse Primary Cortical Neurons.

MAPT GRIN2B

8.19e-06358228899992
Pubmed

Helicobacter pylori-induced epithelial-mesenchymal transition, a potential role of gastric cancer initiation and an emergence of stem cells.

SNAI2 SNAI1

8.19e-06358225784376
Pubmed

Nucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteases.

NPM1 SENP5

8.19e-06358219015314
Pubmed

The snail superfamily of zinc-finger transcription factors.

SNAI2 SNAI1

8.19e-06358211994736
Pubmed

Snail family members unequally trigger EMT and thereby differ in their ability to promote the neoplastic transformation of mammary epithelial cells.

SNAI2 SNAI1

8.19e-06358224638100
Pubmed

Differential role of Snail1 and Snail2 zinc fingers in E-cadherin repression and epithelial to mesenchymal transition.

SNAI2 SNAI1

8.19e-06358224297167
Pubmed

Expression analysis of the mouse S100A7/psoriasin gene in skin inflammation and mammary tumorigenesis.

S100A7 S100A7A

8.19e-06358215717926
Pubmed

HOPX hypermethylation promotes metastasis via activating SNAIL transcription in nasopharyngeal carcinoma.

SNAI2 SNAI1

8.19e-06358228146149
Pubmed

Proteomic Analysis of Epithelial to Mesenchymal Transition (EMT) Reveals Cross-talk between SNAIL and HDAC1 Proteins in Breast Cancer Cells.

SNAI2 SNAI1

8.19e-06358226764010
Pubmed

SMT3IP1, a nucleolar SUMO-specific protease, deconjugates SUMO-2 from nucleolar and cytoplasmic nucleophosmin.

NPM1 SENP5

8.19e-06358218639523
Pubmed

S100A7 enhances mammary tumorigenesis through upregulation of inflammatory pathways.

S100A7 S100A7A

8.19e-06358222158945
Pubmed

Downregulation of miR-95 in gastric cancer promotes EMT via regulation of Slug, thereby promoting migration and invasion.

SNAI2 SNAI1

8.19e-06358230535480
Pubmed

[Time dependent expression profiling of PTK2B and its relationship with Aβ, Tau and LRP-1 in hippocampus and blood of APPswe/PS1dE9 double-transgenic mouse].

MAPT LRP1

8.19e-06358235634664
Pubmed

The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression.

SNAI2 SNAI1

8.19e-06358210655586
Pubmed

Snail promotes lymph node metastasis and Twist enhances tumor deposit formation through epithelial-mesenchymal transition in colorectal cancer.

SNAI2 SNAI1

8.19e-06358222974478
Pubmed

SNAI1 recruits HDAC1 to suppress SNAI2 transcription during epithelial to mesenchymal transition.

SNAI2 SNAI1

8.19e-06358231165775
Pubmed

The transcription factors Slug (SNAI2) and Snail (SNAI1) regulate phospholipase D (PLD) promoter in opposite ways towards cancer cell invasion.

SNAI2 SNAI1

8.19e-06358226781944
Pubmed

Regulation of p63 isoforms by snail and slug transcription factors in human squamous cell carcinoma.

SNAI2 SNAI1

8.19e-06358220150431
Pubmed

The SLUG zinc-finger protein represses E-cadherin in breast cancer.

SNAI2 SNAI1

8.19e-06358211912130
Pubmed

CCL2 expression correlates with Snail expression and affects the prognosis of patients with gastric cancer.

SNAI2 SNAI1

8.19e-06358228215642
Pubmed

Genetic interaction between tau and the apolipoprotein E receptor LRP1 Increases Alzheimer's disease risk.

MAPT LRP1

8.19e-06358219684401
Pubmed

The transcription factors Snail1 and Snail2 repress vitamin D receptor during colon cancer progression.

SNAI2 SNAI1

8.19e-06358220138990
Pubmed

Association study of polymorphisms in LRP1, tau and 5-HTT genes and Alzheimer's disease in a sample of Colombian patients.

MAPT LRP1

8.19e-06358216362633
Pubmed

Comparative analysis of the physical properties of murine and human S100A7: Insight into why zinc piracy is mediated by human but not murine S100A7.

S100A7 S100A7A

8.19e-06358237769710
Pubmed

Comprehensive analysis of the independent effect of twist and snail in promoting metastasis of hepatocellular carcinoma.

SNAI2 SNAI1

8.19e-06358219821482
Pubmed

TOX3 inhibits cancer cell migration and invasion via transcriptional regulation of SNAI1 and SNAI2 in clear cell renal cell carcinoma.

SNAI2 SNAI1

8.19e-06358230772441
Pubmed

The Tau/A152T mutation, a risk factor for frontotemporal-spectrum disorders, leads to NR2B receptor-mediated excitotoxicity.

MAPT GRIN2B

8.19e-06358226931569
Pubmed

Quercetin modulates Wnt signaling components in prostate cancer cell line by inhibiting cell viability, migration, and metastases.

SNAI2 SNAI1

8.19e-06358227495232
Pubmed

Yap1 is required for endothelial to mesenchymal transition of the atrioventricular cushion.

NFATC1 SNAI2 SNAI1

9.86e-062558324831012
Pubmed

Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation.

BMPR1A NFATC1 SNAI1

9.86e-062558316887829
Pubmed

Maternal DNA Methylation Regulates Early Trophoblast Development.

PTPRE SNAI2 SNAI1

1.40e-052858326812015
Pubmed

VAV1 represses E-cadherin expression through the transactivation of Snail and Slug: a potential mechanism for aberrant epithelial to mesenchymal transition in human epithelial ovarian cancer.

SNAI2 SNAI1

1.64e-05458223856093
Pubmed

MiR-22 suppresses epithelial-mesenchymal transition in bladder cancer by inhibiting Snail and MAPK1/Slug/vimentin feedback loop.

SNAI2 SNAI1

1.64e-05458229434190
Pubmed

Transcription factors Snail, Slug, Twist, and SIP1 in spindle cell carcinoma of the head and neck.

SNAI2 SNAI1

1.64e-05458219381684
Pubmed

Snail1, Snail2, and E47 promote mammary epithelial branching morphogenesis.

SNAI2 SNAI1

1.64e-05458221610693
Pubmed

Molecular cloning and characterization of alternatively spliced mRNA isoforms from psoriatic skin encoding a novel member of the S100 family.

S100A7 S100A7A

1.64e-05458212923069
Pubmed

Reciprocal negative regulation between S100A7/psoriasin and beta-catenin signaling plays an important role in tumor progression of squamous cell carcinoma of oral cavity.

S100A7 S100A7A

1.64e-05458218223693
Pubmed

Expression of the E-cadherin repressors Snail, Slug and Zeb1 in urothelial carcinoma of the urinary bladder: relation to stromal fibroblast activation and invasive behaviour of carcinoma cells.

SNAI2 SNAI1

1.64e-05458222820858
Pubmed

Differences in the expression of epithelial-mesenchymal transition related molecules between primary tumors and pulmonary metastatic tumors in colorectal cancer.

SNAI2 SNAI1

1.64e-05458223052737
Pubmed

Snail/Slug-YAP/TAZ complexes cooperatively regulate mesenchymal stem cell function and bone formation.

SNAI2 SNAI1

1.64e-05458228112996
Pubmed

Snail activation disrupts tissue homeostasis and induces fibrosis in the adult kidney.

SNAI2 SNAI1

1.64e-05458217093497
Pubmed

Modulation of beta-catenin and E-cadherin interaction by Vpu increases human immunodeficiency virus type 1 particle release.

SNAI2 SNAI1

1.64e-05458218256147
Pubmed

Differential expression of the epithelial mesenchymal transition factors Snail, Slug, Twist, TGF-β, and E-cadherin in ameloblastoma.

SNAI2 SNAI1

1.64e-05458227995335
Pubmed

Chemotactic activity of S100A7 (Psoriasin) is mediated by the receptor for advanced glycation end products and potentiates inflammation with highly homologous but functionally distinct S100A15.

S100A7 S100A7A

1.64e-05458218606705
Pubmed

HR+HER2- breast cancers with growth factor receptor-mediated EMT have a poor prognosis and lapatinib downregulates EMT in MCF-7 cells.

SNAI2 SNAI1

1.64e-05458228349782
Pubmed

Mutation of LRP1 in cardiac neural crest cells causes congenital heart defects by perturbing outflow lengthening.

NFATC1 LRP1 SNAI1

1.91e-053158332546759
Pubmed

Enhanced epithelial to mesenchymal transition (EMT) and upregulated MYC in ectopic lesions contribute independently to endometriosis.

SNAI2 SNAI1

2.72e-05558226198055
Pubmed

Interaction of SQSTM1 with the motor protein dynein--SQSTM1 is required for normal dynein function and trafficking.

DNAI2 DYNC1I2

2.72e-05558225015291
Pubmed

A genome-wide RNAi screen identifies opposing functions of Snai1 and Snai2 on the Nanog dependency in reprogramming.

SNAI2 SNAI1

2.72e-05558225240402
Pubmed

Endothelial HIF-2α contributes to severe pulmonary hypertension due to endothelial-to-mesenchymal transition.

SNAI2 SNAI1

2.72e-05558229074488
Pubmed

Genomic and phylogenetic analysis of the S100A7 (Psoriasin) gene duplications within the region of the S100 gene cluster on human chromosome 1q21.

S100A7 S100A7A

2.72e-05558212664160
Pubmed

Molecular cloning, occurrence, and expression of a novel partially secreted protein "psoriasin" that is highly up-regulated in psoriatic skin.

S100A7 S100A7A

2.72e-0555821940442
Pubmed

p53 inhibits tumor cell invasion via the degradation of snail protein in hepatocellular carcinoma.

SNAI2 SNAI1

2.72e-05558220385133
Pubmed

Snail regulates MyoD binding-site occupancy to direct enhancer switching and differentiation-specific transcription in myogenesis.

SNAI2 SNAI1

2.72e-05558222771117
Pubmed

Snail/Slug binding interactions with YAP/TAZ control skeletal stem cell self-renewal and differentiation.

SNAI2 SNAI1

2.72e-05558227479603
Pubmed

S100A15, an antimicrobial protein of the skin: regulation by E. coli through Toll-like receptor 4.

S100A7 S100A7A

2.72e-05558217625598
Pubmed

Tau accumulation triggers STAT1-dependent memory deficits by suppressing NMDA receptor expression.

MAPT GRIN2B

2.72e-05558231085626
Pubmed

In vitro treatment of carcinoma cell lines with pancreatic (pro)enzymes suppresses the EMT programme and promotes cell differentiation.

SNAI2 SNAI1

2.72e-05558223677639
Pubmed

Down-regulation of microRNAs of the miR-200 family and up-regulation of Snail and Slug in inflammatory bowel diseases - hallmark of epithelial-mesenchymal transition.

SNAI2 SNAI1

2.72e-05558227113480
Pubmed

Nucleolin modulates the subcellular localization of GDNF-inducible zinc finger protein 1 and its roles in transcription and cell proliferation.

NPM1 NFATC1

2.72e-05558217674968
Pubmed

Sema6D acts downstream of bone morphogenetic protein signalling to promote atrioventricular cushion development in mice.

NFATC1 SNAI2 SNAI1

2.77e-053558328172500
GeneFamilyWD repeat domain containing

AAMP DMXL2 CFAP52 TBL1Y WDR6 POC1B DNAI2 DYNC1I2

1.35e-07262428362
GeneFamilyZinc fingers C2H2-type|SNAG transcriptional repressors

SNAI2 SNAI1

2.34e-04104221259
GeneFamilyS100 calcium binding proteins|EF-hand domain containing

S100A7 S100A7A

1.08e-0321422459
CoexpressionKOHN_EMT_MESENCHYMAL

STARD9 SNAI2 SNAI1

4.59e-0615583M46417
CoexpressionGSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_DN

DMXL2 BMPR1A FBXO10 NDRG1 VWA5A EMILIN2

5.18e-06199586M6028
CoexpressionBAFNA_MUC4_TARGETS_UP

NEK6 SNAI1

4.79e-055582MM709
CoexpressionBAFNA_MUC4_TARGETS_UP

NEK6 SNAI1

4.79e-055582M1699
CoexpressionGSE28449_WT_VS_LRF_KO_GERMINAL_CENTER_BCELL_UP

S100A7 DMXL2 BMPR1A NTSR1 RCBTB2

7.93e-05199585M8347
CoexpressionGSE25123_CTRL_VS_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DN

PTPRE STARD9 ANKRD12 DYNC1I2 TNS3

7.93e-05199585M7998
CoexpressionGSE5589_WT_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_UP

NDRG1 NFATC1 CPT1C RCBTB2 TNS3

8.12e-05200585M6649
CoexpressionGSE5589_LPS_VS_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_UP

HAUS6 PTPRE CPT1C DTX3 RCBTB2

8.12e-05200585M6609
CoexpressionKIM_WT1_TARGETS_UP

PTPRE NFATC1 SNAI2 TNS3 SENP5

1.19e-04217585M9128
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DMXL2 PTPRE NTSR1 EMILIN2 LRP1 SNAI1

1.69e-071925760219093e7921a0db78053aee13ec480b520f5662
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DMXL2 PTPRE NTSR1 EMILIN2 LRP1 SNAI1

1.69e-07192576f14ee74ac3275601749a23c5efe39c2413a62e1a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRE NFATC1 STARD9 GRIN2B ITGA9

2.59e-06170575dcc64b73134e89ae37990d4878813b86ce91dae9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRE NFATC1 STARD9 GRIN2B ITGA9

2.59e-061705756035c92cd39c5ac54e7ec57d94888ee19f574639
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRE NFATC1 STARD9 GRIN2B ITGA9

2.59e-06170575c8c42eda44b61440c96b202e7f54650046eb95d3
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DMXL2 PTPRE NTSR1 EMILIN2 LRP1

3.72e-06183575fcb0f755382d88fb207fc2322cd224c09c6e2ea6
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DMXL2 PTPRE NTSR1 EMILIN2 LRP1

3.72e-061835754763df29c888d47c22076803b054f06b4cc29368
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRR35 NDRG1 GRIN2B AQP2 ADH1C

4.02e-06186575aeac0c2db173cd1ea45b5052ab418d6cacd198d8
ToppCellE18.5-samps-Mesenchymal|E18.5-samps / Age Group, Lineage, Cell class and subclass

SUGP2 SNAI2 LRP1 SNAI1 TNS3

4.35e-061895750c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRR35 NDRG1 GRIN2B AQP2 ADH1C

4.46e-06190575078f4be52fa4cc8dd9c8d7a2b6d9631c3d902285
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4-Gpr17_(Bmp4)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

S100A7A PRR35 DNAI2 DMRTB1

4.55e-0686574eb2b9e98ff97371f497ee1709848a2caaa46ed3d
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4-Gpr17_(Bmp4)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

S100A7A PRR35 DNAI2 DMRTB1

4.55e-068657402ea5219e2faded2b50b96d41861e4f8a558e4e3
ToppCellNS-critical-d_0-4|critical / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

S100A7 DMXL2 EMILIN2 LRP1 TNS3

4.58e-06191575769942a6a31c13c583dc38e8a762df2f5c06c2fb
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DMXL2 NEK6 VWA5A LRP1 TNS3

5.07e-061955759d649ac7d2af313481069c95349efc0c68449e2b
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_monocytic-classical_monocyte|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DMXL2 LINC00482 PTPRE EMILIN2 LRP1

5.07e-06195575580ed65b4152483b642a7e7dbdf00d03588c46f6
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DMXL2 PTPRE EMILIN2 LRP1 SNAI1

5.32e-06197575383d598ce3f8f5fc98bef3300e4cf7b6992aec9c
ToppCellmild_COVID-19-Classical_Monocyte|World / disease group, cell group and cell class (v2)

DMXL2 PTPRE EMILIN2 LRP1 SNAI1

5.32e-061975755d826f4d7b7a46847c67e6bef38eb860bc808a6c
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DMXL2 PTPRE EMILIN2 LRP1 SNAI1

5.32e-061975753cc4e56a77f96a43f9b5a24cf1b9524c927ef795
ToppCellNS-moderate-d_07-13-Myeloid-Non-resident_Macrophage|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DMXL2 PTPRE EMILIN2 LRP1 TNS3

5.32e-06197575774a5053f43ac7d614c127ae7363d32a3a194f63
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DMXL2 HAUS6 EMILIN2 LRP1 TNS3

5.46e-0619857593cc01d91ffc543fd1a717ef47e02e532b50b665
ToppCellsevere-HLA-DR+_CD83+_Monocyte|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DMXL2 PTPRE EMILIN2 LRP1 TNS3

5.46e-06198575a77f3440d7fb6a50066abc7e9ad59e83798ef13d
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DMXL2 NT5DC4 EMILIN2 LRP1 TNS3

5.46e-061985750b41b3d6c2db795320e8b65d40d85fb8b618cc34
ToppCellNS-moderate-d_16-33-Myeloid-Non-resident_Macrophage|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DMXL2 EMILIN2 LRP1 SNAI1 TNS3

5.46e-0619857511a7a553de6786c1e8288251ba0d5c898505c158
ToppCellmoderate-Myeloid-Non-resident_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DMXL2 EMILIN2 LRP1 SNAI1 TNS3

5.59e-061995753895e367a33ac0316f96a64c07574de99684f4b7
ToppCellmoderate-Myeloid-Non-resident_Macrophage|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DMXL2 EMILIN2 LRP1 SNAI1 TNS3

5.59e-06199575614c1e788d89310e78984241977941beed8d12dc
ToppCellBAL-Severe-Myeloid-MoAM|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

DMXL2 PTPRE EMILIN2 LRP1 TNS3

5.73e-0620057543ec6732cc255d533170ebf95d282e503606dcc6
ToppCellBronchial-10x5prime-Immune_Myeloid-Monocytic-Monocyte_CD14|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DMXL2 PTPRE NTSR1 EMILIN2 SNAI1

5.73e-062005751aa4197f1c7c099313dc2e1f8b1153252add7a33
ToppCellBAL-Severe-Myeloid|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

DMXL2 PTPRE EMILIN2 LRP1 TNS3

5.73e-06200575bb246c630b2fde1633b28838a5f087fdfb4bc4a5
ToppCellSevere-Myeloid-Macrophages|Severe / Condition, Lineage, Cell class and cell subclass

DMXL2 PTPRE EMILIN2 LRP1 TNS3

5.73e-06200575ee1d80fa5d4609f9a6b10c33950e888f509a063c
ToppCellSevere_COVID-19-Myeloid|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

DMXL2 PTPRE EMILIN2 LRP1 TNS3

5.73e-062005755a199f2a32dd2cb3a2f2d6ee73798114786a37a2
ToppCellsevere-CD163+_Monocytes_(Sample_ID1_d7)|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DMXL2 LINC00482 EMILIN2 LRP1 TNS3

5.73e-062005754943fe826d5fcc3dfeb8b99a7415848f3fecc994
ToppCellBAL-Severe-Myeloid-MoAM|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DMXL2 PTPRE EMILIN2 LRP1 TNS3

5.73e-0620057560bf9f9d4899245463707016e51cd7243f6405b4
ToppCellBAL-Severe-Myeloid|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DMXL2 PTPRE EMILIN2 LRP1 TNS3

5.73e-062005759bc2e86d84cc7e328950e7273014de5a5d2549c4
ToppCellBronchial-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD14|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DMXL2 PTPRE NTSR1 EMILIN2 LRP1

5.73e-062005755432bdf495431cd26f6e4cd585100f3652588913
ToppCelldroplet-Lung-18m-Hematologic-myeloid-intermediate_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTPRE EMILIN2 LRP1 TAB2

6.35e-0516857400cff4698db14e03ca1d1b409e5ed1ad23b12615
ToppCelldroplet-Lung-18m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTPRE EMILIN2 LRP1 TAB2

6.50e-0516957490c00ab30e582b0e2a2be751e1fae9024cfb9ea6
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRR35 NDRG1 AQP2 ADH1C

6.65e-05170574928e42c51a7079c506f21c669c4e4c1a0df84d77
ToppCell10x5'-Liver-Myeloid_Mac-Intermediate_macrophages|Liver / Manually curated celltypes from each tissue

DMXL2 NDRG1 SNAI1 CHRNA2

6.80e-0517157425e0333743affdb662223fb5220b8a61fa02ad9f
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DMXL2 PTPRE EMILIN2 LRP1

7.11e-05173574279efbab7810fa60ab12ea5d09a84800df4adef0
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAM151A SNAI2 SNAI1 TNS3

7.60e-05176574cb8fd56a4f935cdda19d7ab43382cdda7c307667
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DMXL2 PTPRE EMILIN2 LRP1

7.60e-051765746548797336c9f4ca0f38e74a2c629e2a4defa252
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

EMILIN2 LRP1 SNAI1 ITGA9

7.77e-05177574382f0d6bbff01e84b0c7840e74ac865864e6da89
ToppCell10x5'-GI_large-bowel-Mast-Mast_cells|GI_large-bowel / Manually curated celltypes from each tissue

BMPR1A VWA5A BSPRY EMILIN2

7.94e-051785748fc5f735afa25ae43c2acb1c710ade6e9e093e3c
ToppCell10x5'-GI_large-bowel-Mast|GI_large-bowel / Manually curated celltypes from each tissue

BMPR1A VWA5A BSPRY EMILIN2

7.94e-05178574d10ed2543c96e1a2373f847e0b82144771e26d07
ToppCellLPS_only-Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DMXL2 PTPRE EMILIN2 LRP1

8.12e-05179574dc03b9045510eb1bb934329646bb92dd06890ce9
ToppCellLPS_only-Myeloid-Monocytes,_Macrophages|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DMXL2 PTPRE EMILIN2 LRP1

8.12e-05179574330c1326ba93bb8f32559ee1cc40e357cc44ad8d
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SNAI2 SNAI1 TNS3 ADH1C

8.12e-05179574b559f5a72cc9e3e35d05cb539b5c2e006e56e652
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRR35 NDRG1 AQP2 ADH1C

8.47e-05181574c2a8ee8679a1d71fcbff792cd516d3ce114f3ca6
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast|E18.5-samps / Age Group, Lineage, Cell class and subclass

SNAI2 LRP1 SNAI1 TNS3

8.66e-05182574ceb37c214662a48efb56ab0d015977c6fab478b0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRR35 NDRG1 GRIN2B AQP2

8.84e-05183574b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DMXL2 PTPRE EMILIN2 SNAI1

9.03e-05184574d1ea2b60fb1ca1a0b809d131310c43903a9e84ce
ToppCellE16.5-samps-Mesenchymal|E16.5-samps / Age Group, Lineage, Cell class and subclass

SNAI2 LRP1 SNAI1 TNS3

9.81e-051885743f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_naive-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DMXL2 PTPRE EMILIN2 SNAI1

1.00e-0418957455aba1ebc012006a5db3ff9c92589cb3d9f7c68a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRR35 NDRG1 GRIN2B AQP2

1.00e-04189574bfc76a72b600d641c8fe58346e5d8986c34f3981
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRR35 NDRG1 GRIN2B AQP2

1.02e-0419057411d3c31167ea71809b4cc3757a0c6ea54a448602
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_monocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DMXL2 PTPRE EMILIN2 LRP1

1.02e-0419057400ef6ec71353e42260c0d807d7da65b63154c288
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DMXL2 PTPRE EMILIN2 LRP1

1.02e-0419057418c020ca9a23399214133ec255ab870e0060f2e1
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal|E16.5-samps / Age Group, Lineage, Cell class and subclass

MAPT SNAI2 LRP1 TNS3

1.04e-041915743379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCellCOVID-19-lung-Macrophage_PPARGhi_CD5Lhi|lung / Disease (COVID-19 only), tissue and cell type

DMXL2 EMILIN2 LRP1 TNS3

1.04e-04191574dab953682b8c9ed680a799161f837f792a7e4f33
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRR35 NDRG1 GRIN2B AQP2

1.04e-041915747235a4d1601c88a2c8af571a2c04ab56d32f1b9a
ToppCellCOVID-19-lung-Macrophage_PPARGhi_CD5Lhi|COVID-19 / Disease (COVID-19 only), tissue and cell type

DMXL2 EMILIN2 LRP1 TNS3

1.06e-04192574bcfb9c005166bc0b4f8ee2dfc0c1540e8bf0e1ff
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRR35 NDRG1 AQP2 ADH1C

1.06e-04192574d5ec4cdb15620a5abfc83577353501186c2bc86a
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)-D175|Adult / Lineage, Cell type, age group and donor

DMXL2 NEK6 LRP1 TNS3

1.06e-04192574733491e932350e3c216a626cc49c3cd3fe970a82
ToppCellControl-Myeloid-cMonocyte|Control / Disease state, Lineage and Cell class

NDRG1 LINC00482 PTPRE EMILIN2

1.06e-04192574ad04c9c4bdebf94615cee1904ca48197e62c923b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRR35 NDRG1 GRIN2B AQP2

1.06e-04192574fd08ae787e936cfdb1ab8f19b0fd63005b462709
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRR35 NDRG1 AQP2 ADH1C

1.06e-041925749e031bf93eb8757fdd0cc22f01b44e48f85532d5
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRR35 NDRG1 AQP2 ADH1C

1.06e-041925743d777d07878269b87ec7e1f06489cae7c989d633
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DMXL2 PTPRE EMILIN2 LRP1

1.09e-041935745f732598cdb6f3bd519f044a9cc553bd2e8b1052
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DMXL2 PTPRE NEK6 EMILIN2

1.09e-04193574bd08555f02db8bc903caacae57e80bb91e2556ce
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRR35 NDRG1 AQP2 ADH1C

1.09e-04193574371f4c98a599923fbe8382530b3eab05d873665a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRR35 NDRG1 GRIN2B AQP2

1.09e-04193574e7012f7b53971972299db34fa51ff51a4e4987fe
ToppCellLeuk-UTI-Myeloid-CD14_Mono|Leuk-UTI / Disease, Lineage and Cell Type

DMXL2 LINC00482 EMILIN2 LRP1

1.09e-04193574d1eac8627d00629ed2e81d3b86778007304efcb7
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

NEK6 EMILIN2 LRP1 SNAI1

1.09e-0419357452f5b0fbb8ca706206c65e7edbb1ddbd380aebae
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DMXL2 PTPRE NEK6 EMILIN2

1.09e-04193574374d0526a071e973c3f43b4564f78f6933bb67ed
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SNAI2 SNAI1 TNS3 ADH1C

1.09e-04193574b637e1c47a98009e7d19a6daac78f888fd12748f
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)|Adult / Lineage, Cell type, age group and donor

DMXL2 EMILIN2 LRP1 RCBTB2

1.09e-0419357431c0978ba78c9516d498aec0798902e57555e557
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRR35 NDRG1 AQP2 ADH1C

1.09e-041935745da60321bcf761913eb30779b6d8b1e933c5e51e
ToppCellCF-Myeloid-Monocyte|CF / Disease state, Lineage and Cell class

DMXL2 EMILIN2 LRP1 SNAI1

1.09e-041935743a83b2593a37a075f91354745e5a7a081ec406a8
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRR35 NDRG1 AQP2 ADH1C

1.11e-04194574158dc393639e69aecfb014f6106797214ea05fe5
ToppCellPND01-03-samps-Mesenchymal|PND01-03-samps / Age Group, Lineage, Cell class and subclass

SNAI2 LRP1 SNAI1 TNS3

1.11e-041945744f9bd0ded0dde1df885850714f29e73e992539a5
ToppCellE15.5-Mesenchymal-developing_mesenchymal_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MAPT SNAI2 SNAI1 ADH1C

1.11e-04194574d840c1949c328779426c9172e02da09e968f0567
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SNAI2 SNAI1 TNS3 ADH1C

1.11e-04194574f2f7b9aad7588c8020a4850ff9333e1db8eafac7
ToppCellHealthy-Classical_Monocyte|World / disease group, cell group and cell class

DMXL2 PTPRE EMILIN2 LRP1

1.13e-041955740d96f456cc84ebb2543406fb2374c6d7cedd3c4d
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_monocytic-intermediate_monocyte|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DMXL2 PTPRE EMILIN2 LRP1

1.13e-04195574403d874198a7bde626b0d0b4efad8dbb34060761
ToppCellControl-Classical_Monocyte-cMono_2|Control / Disease condition and Cell class

DMXL2 PTPRE EMILIN2 LRP1

1.13e-041955740fea64ee3eedf3929abb0dd9c5f5fc72f181eed9
ToppCellPND01-Mesenchymal-Mesenchymal_structural|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAPT SNAI2 LRP1 TNS3

1.13e-041955746bb6349d6ec8da094fe1c7c590021989337aeb0b
ToppCellImmune-alveolar_macrophage_(MARCO_positive)|World / Lineage, Cell type, age group and donor

DMXL2 EMILIN2 LRP1 TNS3

1.13e-04195574f92114ef995e690a3bedc62c89c5fd6773d0d9f7
ToppCellmild-dn_T|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CCDC14 NFATC1 DTX3 BSPRY

1.13e-04195574158f0f229bad71cc9b06b7399168982bbbbd1d47
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|lung / Disease (COVID-19 only), tissue and cell type

DMXL2 EMILIN2 LRP1 TNS3

1.13e-04195574148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DMXL2 PTPRE EMILIN2 LRP1

1.13e-041955740110b976f98561ecd2e20ff6e7e3960a401bb7c2
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)|Adult / Lineage, Cell type, age group and donor

DMXL2 EMILIN2 LRP1 TNS3

1.13e-0419557455e25f702af19146a161861cfd15f40bbda1dc35
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAPT SNAI2 LRP1 TNS3

1.13e-04195574a3b468125e48f072255cede7645f6692298ecf54
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DMXL2 PTPRE EMILIN2 LRP1

1.13e-04195574050fc59b328391d6e3ce23051764a842dcbb3144
ToppCellsevere-Classical_Monocyte|World / disease stage, cell group and cell class

DMXL2 LINC00482 PTPRE LRP1

1.13e-04195574cf638aac4d57ae0774008920a1a5e9dfd8c73885
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRR35 NDRG1 AQP2 ADH1C

1.13e-041955740ac7762197cdd8d643f87148573a8df6e936c1b0
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_monocytic|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DMXL2 PTPRE EMILIN2 LRP1

1.15e-04196574f943519bff51c3094776fd45889dadf9062c8379
ToppCellHealthy-Classical_Monocyte|Healthy / disease group, cell group and cell class

DMXL2 PTPRE EMILIN2 LRP1

1.15e-0419657427d24aa2fd4521cf7e410688ed3b11b2d9700dd2
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SNAI2 LRP1 SNAI1 TNS3

1.15e-04196574db64ab27374f82553ee577aec056141170f3656f
ToppCellE17.5-Mesenchymal|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SNAI2 SNAI1 TNS3 ADH1C

1.15e-04196574b4ee991445b612506372b9361ebfe72cb59b811e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRR35 NDRG1 AQP2 ADH1C

1.15e-04196574cd8c22c6f52f068a33525723108d6b5b23fe822d
DiseaseNRF2 measurement

NTSR1 GRIN2B

9.48e-058552EFO_0009794
DiseaseParkinson disease, late-onset

MAPT ADH1C

1.52e-0410552cv:C3160718
DiseasePARKINSON DISEASE, LATE-ONSET

MAPT ADH1C

1.52e-0410552168600
Diseaselate onset Parkinson's disease (is_implicated_in)

MAPT ADH1C

1.86e-0411552DOID:0060892 (is_implicated_in)
DiseasePARKINSON DISEASE, LATE-ONSET

MAPT ADH1C

2.22e-0412552C3160718
DiseaseAnilide use measurement

MAPT LRP1

3.53e-0415552EFO_0009938
Diseasealcohol use disorder (is_implicated_in)

GRIN2B ADH1C

4.03e-0416552DOID:1574 (is_implicated_in)
DiseaseParkinson disease

MAPT ADH1C

7.69e-0422552cv:C0030567
Diseasevascular endothelial function measurement

DNAI2 TAB2 ANKRD12

8.47e-0499553EFO_0803369
Diseasecongenital heart disease (is_implicated_in)

NFATC1 TAB2

9.17e-0424552DOID:1682 (is_implicated_in)
DiseaseDrugs affecting bone structure and mineralization use measurement

NFATC1 ZBTB40

1.34e-0329552EFO_0009936
DiseaseC-reactive protein measurement

DMXL2 NEK6 UBP1 ENTR1 NTSR1 POC1B ZBTB40 ADH1C

1.68e-031206558EFO_0004458

Protein segments in the cluster

PeptideGeneStartEntry
GHLLGIHYTGCSMNP

AQP2

171

P41181
HVLKGTEGHQGPLTC

AAMP

251

Q13685
FTCSGKPIHHFVGVS

ADH1C

131

P00326
GHIQVHGPGTCQVKF

FBXO10

211

Q9UK96
AGHVAPSVGTLCSHG

CHRNA2

426

Q15822
ISPGNSLIHGFTCHD

DMXL2

2886

Q8TDJ6
FHISTGKSPKHSCGL

ANKRD12

536

Q6UB98
TSAEKIVCTFPGHHG

DNAI2

351

Q9GZS0
HGPSGCLSNSLQVKG

CCDC14

881

Q49A88
RLKCGSGPVHISGQH

NPM1

101

P06748
LGNGTTNHGLVPCHI

RCBTB2

131

O95199
TGNHPITVHCSAGAG

PTPRE

621

P23469
LTGKHERHFSISGCP

KAT7

196

O95251
GQHAGGLVCTPTIHT

NTSR1

216

P30989
HKFGHSPLVNLTGGL

LRP1

4116

Q07954
QGPITGIHCHAAVGA

DYNC1I2

476

Q13409
GFNGHVPTGLKCHPD

CFAP52

21

Q8N1V2
HGSVHVTLCGTPKGN

NDRG1

41

Q92597
YTKGVASPGHCHLGL

NFATC1

776

O95644
GGSSNNLCHTLGPVH

NEK6

11

Q9HC98
VHSGGVNCISFHPSG

POC1B

226

Q8TC44
KFVDVGGHSHGCTPL

PCDHGC4

761

Q9Y5F7
VSPKISAGHQHCGQS

GPR75

456

O95800
IHSLHCGGGPKSRAK

PRR35

121

P0CG20
TCFSFHGKHVPGEIG

ITGA9

496

Q13797
GKLHVGTSTGPHQHC

NT5DC4

276

Q86YG4
FQLGYSTDGHCKGHP

CPT1C

491

Q8TCG5
IHHKTSCTGGPQLFG

DTX3

311

Q8N9I9
FNQGHSCGSPKVSHT

LINC00482

246

Q8N8I6
ASGTVLCAHHVSFPG

BSPRY

371

Q5W0U4
NHGFLVPVKGHAGKC

DMRTB1

16

Q96MA1
KISHGSFSVPGHVAG

FAM151A

446

Q8WW52
KCSKQSPSGAHGTHF

ENTR1

81

Q96C92
GLCHLHTEIYGTQGK

BMPR1A

341

P36894
SFLSGPITHHKGCVA

ADGRF2

506

Q8IZF7
GPATIACGKIVSHTH

HAUS6

26

Q7Z4H7
QSCTLSGGKHHGPVE

LAS2

281

Q8IYD9
TCGGPGAFHLIVHLK

EMILIN2

1001

Q9BXX0
GKESCPVIFGHVQGH

HELZ2

2461

Q9BYK8
VKIHCRLSGGLPGHS

GPRIN2

276

O60269
YHKQSHGAAPCSGGS

S100A7A

86

Q86SG5
GSHKSPLESLSLHGC

SCP2D1-AS1

31

Q9BR46
TGGIQKAFSTCGPHL

OR1E3

231

Q8WZA6
SAPHLGFHLGSKGTS

TAB2

151

Q9NYJ8
QGHIRTHTGEKPFSC

SNAI2

201

O43623
PGDGASHTKVHFRCV

POLR3H

61

Q9Y535
RKNGLHSSGHGQPCT

STARD9

891

Q9P2P6
GPQSAHLGPFTCHKS

TNS3

501

Q68CZ2
QGHVRTHTGEKPFSC

SNAI1

196

O95863
SHVPDCHTKGSSFLG

SENP5

321

Q96HI0
YHKQSHGAAPCSGGS

S100A7

86

P31151
ICFTSSPHNLHTGGG

SUGP2

841

Q8IX01
TSKCGSLGNIHHKPG

MAPT

636

P10636
SLCGLISHKDQHSPG

VWA5A

661

O00534
LGCDHPVKTFQGHTN

TBL1Y

346

Q9BQ87
LHGKQGVTSVTCHGG

WDR6

566

Q9NNW5
VHCISTEFTPRKHGG

UBP1

186

Q9NZI7
GNIHAICGVPSQHGT

ZBED9

621

Q6R2W3
CGKAFSQKSHLPGHQ

ZNF300

526

Q96RE9
HVVTHVGGKPFSCGI

ZBTB40

996

Q9NUA8
GPCTNRSHIKHGTGD

GRIN2B

1171

Q13224