Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane transporter activity	TMEM144 SLC9A3 SLC44A1 ATP2C1 SLC11A2 ABCB5 SLC39A4 SLC12A8 TMEM109 TAP2 ANO3 RHCE RHD	2.62e-05	1180	58	13	GO:0022857
GeneOntologyMolecularFunction	transporter activity	TMEM144 SLC9A3 SLC44A1 ATP2C1 SLC11A2 ABCB5 SLC39A4 SLC12A8 TMEM109 TAP2 ANO3 RHCE RHD	6.54e-05	1289	58	13	GO:0005215
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC9A3 SLC44A1 ATP2C1 SLC11A2 ABCB5 SLC39A4 SLC12A8 TAP2	6.72e-05	477	58	8	GO:0022804
GeneOntologyMolecularFunction	transition metal ion transmembrane transporter activity	ATP2C1 SLC11A2 SLC39A4	2.83e-04	44	58	3	GO:0046915
GeneOntologyMolecularFunction	manganese ion transmembrane transporter activity	ATP2C1 SLC11A2	3.68e-04	10	58	2	GO:0005384
GeneOntologyMolecularFunction	ammonium channel activity	RHCE RHD	5.37e-04	12	58	2	GO:0008519
GeneOntologyMolecularFunction	iron ion binding	CYP4F8 SLC11A2 CYP4B1 CYP24A1	1.38e-03	166	58	4	GO:0005506
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SLC9A3 ATP2C1 SLC11A2 SLC39A4 SLC12A8 ANO3 RHCE RHD	1.49e-03	758	58	8	GO:0015318
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC9A3 SLC44A1 SLC11A2 SLC39A4 SLC12A8	1.67e-03	296	58	5	GO:0015291
GeneOntologyMolecularFunction	active monoatomic ion transmembrane transporter activity	SLC9A3 ATP2C1 SLC11A2 SLC39A4 SLC12A8	1.80e-03	301	58	5	GO:0022853
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SLC9A3 ATP2C1 SLC11A2 SLC39A4 SLC12A8 RHCE RHD	2.18e-03	627	58	7	GO:0022890
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ATP2C1 ABCB5 TAP2	3.93e-03	109	58	3	GO:0042626
GeneOntologyMolecularFunction	actin filament binding	FLNA FLNC PLS1 PLS3	4.27e-03	227	58	4	GO:0051015
GeneOntologyMolecularFunction	monooxygenase activity	CYP4F8 CYP4B1 CYP24A1	4.56e-03	115	58	3	GO:0004497
GeneOntologyMolecularFunction	aromatase activity	CYP4F8 CYP4B1	4.64e-03	35	58	2	GO:0070330
GeneOntologyMolecularFunction	solute:monoatomic cation symporter activity	SLC11A2 SLC39A4 SLC12A8	5.02e-03	119	58	3	GO:0015294
GeneOntologyMolecularFunction	calcium ion binding	TBC1D9B ATP2C1 DSC2 DSC3 PCDHGA12 PLS1 PLS3	5.80e-03	749	58	7	GO:0005509
GeneOntologyBiologicalProcess	cell-cell adhesion via plasma-membrane adhesion molecules	ATP2C1 DSC2 DSC3 PCDHGA12 MDGA2 ITGA3 ITGB2	2.13e-05	313	56	7	GO:0098742
GeneOntologyBiologicalProcess	learning or memory	PTCHD1 SLC11A2 CKAP5 EIF2AK4 ITGA3 ADGRF1 TAFA2	6.47e-05	373	56	7	GO:0007611
GeneOntologyBiologicalProcess	multicellular organismal-level iron ion homeostasis	SLC11A2 RHCE RHD	8.89e-05	32	56	3	GO:0060586
GeneOntologyBiologicalProcess	ammonium homeostasis	RHCE RHD	1.08e-04	6	56	2	GO:0097272
GeneOntologyBiologicalProcess	memory	PTCHD1 EIF2AK4 ITGA3 ADGRF1 TAFA2	1.38e-04	183	56	5	GO:0007613
GeneOntologyBiologicalProcess	cognition	PTCHD1 SLC11A2 CKAP5 EIF2AK4 ITGA3 ADGRF1 TAFA2	1.42e-04	423	56	7	GO:0050890
GeneOntologyBiologicalProcess	myeloid cell development	FLNA SLC11A2 RHCE RHD	2.19e-04	109	56	4	GO:0061515
GeneOntologyBiologicalProcess	integrin-mediated signaling pathway	FLNA ITGA10 ITGA3 ITGB2	3.59e-04	124	56	4	GO:0007229
GeneOntologyBiologicalProcess	actin filament network formation	PLS1 PLS3	3.92e-04	11	56	2	GO:0051639
GeneOntologyBiologicalProcess	positive regulation of protein localization to membrane	ATP2C1 ITGA3 ITGB2 PLS1	4.29e-04	130	56	4	GO:1905477
GeneOntologyBiologicalProcess	erythrocyte development	SLC11A2 RHCE RHD	4.50e-04	55	56	3	GO:0048821
GeneOntologyBiologicalProcess	manganese ion transmembrane transport	ATP2C1 SLC11A2	4.70e-04	12	56	2	GO:0071421
GeneOntologyBiologicalProcess	ammonium transmembrane transport	RHCE RHD	5.54e-04	13	56	2	GO:0072488
GeneOntologyBiologicalProcess	cell-cell adhesion	FLNA ATP2C1 DSC2 DSC3 PCDHGA12 ITGA10 MDGA2 ITGA3 ITGB2 GNRH1	5.74e-04	1077	56	10	GO:0098609
GeneOntologyBiologicalProcess	monoatomic cation homeostasis	FLNA SLC9A3 ATP2C1 SLC11A2 SLC39A4 SLC12A8 RHCE RHD	5.96e-04	705	56	8	GO:0055080
GeneOntologyBiologicalProcess	inorganic ion import across plasma membrane	SLC9A3 SLC11A2 SLC39A4 SLC12A8	5.99e-04	142	56	4	GO:0099587
GeneOntologyBiologicalProcess	inorganic cation import across plasma membrane	SLC9A3 SLC11A2 SLC39A4 SLC12A8	5.99e-04	142	56	4	GO:0098659
GeneOntologyBiologicalProcess	behavior	PTCHD1 SLC11A2 CWH43 CKAP5 MDGA2 EIF2AK4 ITGA3 ADGRF1 TAFA2	6.14e-04	891	56	9	GO:0007610
GeneOntologyBiologicalProcess	manganese ion transport	ATP2C1 SLC11A2	6.45e-04	14	56	2	GO:0006828
GeneOntologyBiologicalProcess	monoatomic ion homeostasis	FLNA SLC9A3 ATP2C1 SLC11A2 SLC39A4 SLC12A8 RHCE RHD	6.66e-04	717	56	8	GO:0050801
GeneOntologyCellularComponent	integrin complex	ITGA10 ITGA3 ITGB2	9.50e-05	32	58	3	GO:0008305
GeneOntologyCellularComponent	ankyrin-1 complex	RHCE RHD	3.36e-04	10	58	2	GO:0170014
GeneOntologyCellularComponent	cluster of actin-based cell projections	FLNA SLC9A3 SLC11A2 PLS1 PLS3	3.82e-04	223	58	5	GO:0098862
GeneOntologyCellularComponent	protein complex involved in cell adhesion	ITGA10 ITGA3 ITGB2	5.90e-04	59	58	3	GO:0098636
GeneOntologyCellularComponent	brush border	FLNA SLC9A3 SLC11A2 PLS1	8.40e-04	152	58	4	GO:0005903
HumanPheno	Flat sella turcica	FLNA ALDH18A1	2.51e-05	2	26	2	HP:0100857
HumanPheno	Hypochromia	SLC11A2 RHCE RHD	2.52e-05	12	26	3	HP:0032231
HumanPheno	Positive direct antiglobulin test	RHCE RHD	7.49e-05	3	26	2	HP:0032366
HumanPheno	Anti-erythrocyte autoantibody positivity	RHCE RHD	7.49e-05	3	26	2	HP:6000388
Domain	Actinin_actin-bd_CS	FLNA FLNC PLS1 PLS3	6.61e-07	23	57	4	IPR001589
Domain	ACTININ_2	FLNA FLNC PLS1 PLS3	6.61e-07	23	57	4	PS00020
Domain	ACTININ_1	FLNA FLNC PLS1 PLS3	6.61e-07	23	57	4	PS00019
Domain	CH	FLNA FLNC PLS1 PLS3	4.59e-05	65	57	4	SM00033
Domain	Integrin_dom	ITGA10 ITGA3 ITGB2	5.91e-05	25	57	3	IPR032695
Domain	CH	FLNA FLNC PLS1 PLS3	6.15e-05	70	57	4	PF00307
Domain	-	FLNA FLNC PLS1 PLS3	6.50e-05	71	57	4	1.10.418.10
Domain	TM4_1	TSPAN31 TSPAN10 TSPAN7	6.67e-05	26	57	3	PS00421
Domain	CH	FLNA FLNC PLS1 PLS3	7.25e-05	73	57	4	PS50021
Domain	CH-domain	FLNA FLNC PLS1 PLS3	8.06e-05	75	57	4	IPR001715
Domain	Ammonium_transpt	RHCE RHD	9.10e-05	5	57	2	IPR001905
Domain	Ammonium_transp	RHCE RHD	9.10e-05	5	57	2	PF00909
Domain	NH4_transpt_AmtB-like_dom	RHCE RHD	9.10e-05	5	57	2	IPR024041
Domain	RhesusRHD	RHCE RHD	9.10e-05	5	57	2	IPR002229
Domain	Tetraspanin	TSPAN31 TSPAN10 TSPAN7	1.26e-04	32	57	3	IPR000301
Domain	Tetraspannin	TSPAN31 TSPAN10 TSPAN7	1.38e-04	33	57	3	PF00335
Domain	Tetraspanin/Peripherin	TSPAN31 TSPAN10 TSPAN7	1.38e-04	33	57	3	IPR018499
Domain	-	RHCE RHD	1.90e-04	7	57	2	1.10.3430.10
Domain	Desmosomal_cadherin	DSC2 DSC3	1.90e-04	7	57	2	IPR009122
Domain	Cadherin_pro	DSC2 DSC3	1.90e-04	7	57	2	PF08758
Domain	Ammonium/urea_transptr	RHCE RHD	1.90e-04	7	57	2	IPR029020
Domain	Cadherin_pro_dom	DSC2 DSC3	2.53e-04	8	57	2	IPR014868
Domain	Cadherin_pro	DSC2 DSC3	2.53e-04	8	57	2	SM01055
Domain	Cyt_P450_E_grp-I	CYP4F8 CYP4B1 CYP24A1	3.49e-04	45	57	3	IPR002401
Domain	IG_FLMN	FLNA FLNC	4.05e-04	10	57	2	SM00557
Domain	Filamin	FLNA FLNC	4.94e-04	11	57	2	PF00630
Domain	Filamin/ABP280_rpt	FLNA FLNC	4.94e-04	11	57	2	IPR001298
Domain	Filamin/ABP280_repeat-like	FLNA FLNC	4.94e-04	11	57	2	IPR017868
Domain	FILAMIN_REPEAT	FLNA FLNC	4.94e-04	11	57	2	PS50194
Domain	Cyt_P450_CS	CYP4F8 CYP4B1 CYP24A1	5.67e-04	53	57	3	IPR017972
Domain	CYTOCHROME_P450	CYP4F8 CYP4B1 CYP24A1	7.02e-04	57	57	3	PS00086
Domain	-	CYP4F8 CYP4B1 CYP24A1	7.38e-04	58	57	3	1.10.630.10
Domain	p450	CYP4F8 CYP4B1 CYP24A1	7.38e-04	58	57	3	PF00067
Domain	Cyt_P450	CYP4F8 CYP4B1 CYP24A1	8.15e-04	60	57	3	IPR001128
Domain	Integrin_alpha-2	ITGA10 ITGA3	1.36e-03	18	57	2	IPR013649
Domain	Integrin_alpha2	ITGA10 ITGA3	1.36e-03	18	57	2	PF08441
Domain	Integrin_alpha	ITGA10 ITGA3	1.36e-03	18	57	2	IPR000413
Domain	INTEGRIN_ALPHA	ITGA10 ITGA3	1.36e-03	18	57	2	PS00242
Domain	Int_alpha_beta-p	ITGA10 ITGA3	1.51e-03	19	57	2	IPR013519
Domain	Int_alpha	ITGA10 ITGA3	1.51e-03	19	57	2	SM00191
Domain	Tetraspanin_CS	TSPAN10 TSPAN7	1.85e-03	21	57	2	IPR018503
Domain	FG_GAP	ITGA10 ITGA3	2.03e-03	22	57	2	PS51470
Domain	FG-GAP	ITGA10 ITGA3	2.42e-03	24	57	2	PF01839
Domain	FG-GAP	ITGA10 ITGA3	2.42e-03	24	57	2	IPR013517
Domain	ABC_membrane	ABCB5 TAP2	2.42e-03	24	57	2	PF00664
Domain	Cadherin_C	DSC2 DSC3	2.62e-03	25	57	2	PF01049
Domain	Cadherin_cytoplasmic-dom	DSC2 DSC3	2.62e-03	25	57	2	IPR000233
Domain	Endo/exonuclease/phosphatase	CWH43 INPPL1	3.06e-03	27	57	2	IPR005135
Domain	ABC_TM1F	ABCB5 TAP2	3.29e-03	28	57	2	PS50929
Domain	ABC1_TM_dom	ABCB5 TAP2	3.29e-03	28	57	2	IPR011527
Domain	VWF_A	TSPAN10 ITGA10 ITGB2	3.44e-03	99	57	3	IPR002035
Domain	Catenin_binding_dom	DSC2 DSC3	3.52e-03	29	57	2	IPR027397
Domain	-	DSC2 DSC3	3.52e-03	29	57	2	4.10.900.10
Domain	Tetraspanin_EC2	TSPAN10 TSPAN7	4.28e-03	32	57	2	IPR008952
Domain	Cadherin_CS	DSC2 DSC3 PCDHGA12	4.50e-03	109	57	3	IPR020894
Domain	GPS	ADGRF1 ADGRD1	4.82e-03	34	57	2	SM00303
Domain	Cadherin	DSC2 DSC3 PCDHGA12	4.98e-03	113	57	3	PF00028
Domain	CADHERIN_1	DSC2 DSC3 PCDHGA12	4.98e-03	113	57	3	PS00232
Domain	CADHERIN_2	DSC2 DSC3 PCDHGA12	5.10e-03	114	57	3	PS50268
Domain	-	DSC2 DSC3 PCDHGA12	5.10e-03	114	57	3	2.60.40.60
Domain	GPS	ADGRF1 ADGRD1	5.10e-03	35	57	2	PF01825
Domain	CA	DSC2 DSC3 PCDHGA12	5.23e-03	115	57	3	SM00112
Domain	Cadherin-like	DSC2 DSC3 PCDHGA12	5.35e-03	116	57	3	IPR015919
Domain	GPS	ADGRF1 ADGRD1	5.39e-03	36	57	2	PS50221
Domain	Cadherin	DSC2 DSC3 PCDHGA12	5.61e-03	118	57	3	IPR002126
Domain	GPS	ADGRF1 ADGRD1	5.69e-03	37	57	2	IPR000203
Pathway	PID_INTEGRIN_CS_PATHWAY	ITGA10 ITGA3 ITGB2	4.15e-05	26	37	3	M47
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	SLC9A3 SLC44A1 ATP2C1 SLC11A2 PSME4 ABCB5 SLC39A4 ANO3	3.16e-04	681	37	8	MM14985
Pathway	WP_NPHP1_DELETION_SYNDROME	FLNA FLNC	3.63e-04	11	37	2	M48099
Pathway	REACTOME_EICOSANOIDS	CYP4F8 CYP4B1	4.35e-04	12	37	2	M27129
Pathway	REACTOME_EICOSANOIDS	CYP4F8 CYP4B1	4.35e-04	12	37	2	MM14845
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	SLC9A3 SLC44A1 ATP2C1 SLC11A2 PSME4 ABCB5 SLC39A4 ANO3	5.32e-04	736	37	8	M27287
Pathway	WP_OXIDATION_BY_CYTOCHROME_P450	CYP4F8 CYP4B1 CYP24A1	5.66e-04	62	37	3	M39653
Pathway	REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE	CYP4F8 CYP4B1 CYP24A1	6.21e-04	64	37	3	M5650
Pathway	REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE	CYP4F8 CYP4B1 CYP24A1	6.80e-04	66	37	3	MM14839
Pathway	REACTOME_FATTY_ACIDS	CYP4F8 CYP4B1	6.89e-04	15	37	2	M27126
Pathway	WP_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY	DSC2 ITGA10 ITGA3	9.49e-04	74	37	3	M39462
Pathway	KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC	DSC2 ITGA10 ITGA3	9.49e-04	74	37	3	M16376
Pathway	REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS	FLNA FLNC	9.99e-04	18	37	2	MM15123
Pathway	REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS	FLNA FLNC	9.99e-04	18	37	2	M840
Pathway	REACTOME_MISCELLANEOUS_SUBSTRATES	CYP4F8 CYP4B1	9.99e-04	18	37	2	MM14843
Pathway	REACTOME_FATTY_ACIDS	CYP4F8 CYP4B1	9.99e-04	18	37	2	MM14841
Pathway	REACTOME_METABOLISM_OF_LIPIDS	CYP4F8 SLC44A1 OXCT1 CYP4B1 INPPL1 CYP24A1 GPAT3	1.00e-03	620	37	7	MM15193
Pathway	REACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS	SLC44A1 SLC11A2 SLC39A4	1.03e-03	76	37	3	MM15072
Pathway	REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS	ITGA10 ITGA3 ITGB2	1.03e-03	76	37	3	MM14867
Pathway	REACTOME_METAL_ION_SLC_TRANSPORTERS	SLC11A2 SLC39A4	1.24e-03	20	37	2	MM15077
Pathway	REACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX	CYP4F8 CYP4B1	1.36e-03	21	37	2	M27137
Pathway	REACTOME_BLOOD_GROUP_SYSTEMS_BIOSYNTHESIS	RHCE RHD	1.36e-03	21	37	2	M27917
Pathway	REACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS	SLC44A1 SLC11A2 SLC39A4	1.37e-03	84	37	3	M27334
Pathway	WP_FOCAL_ADHESION	FLNA ITGA10 ITGA3 ITGB2	1.41e-03	187	37	4	MM15913
Pathway	REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS	ITGA10 ITGA3 ITGB2	1.42e-03	85	37	3	M16441
Pathway	KEGG_MEDICUS_REFERENCE_ITGA_B_RHOGAP_RHOA_SIGNALING_PATHWAY	ITGA10 ITGA3	1.64e-03	23	37	2	M47537
Pathway	KEGG_MEDICUS_REFERENCE_ITGA_B_RHOGEF_RHOA_SIGNALING_PATHWAY	ITGA10 ITGA3	1.64e-03	23	37	2	M47720
Pathway	WP_FOCAL_ADHESION	FLNA FLNC ITGA10 ITGA3	1.77e-03	199	37	4	M39402
Pathway	KEGG_FOCAL_ADHESION	FLNA FLNC ITGA10 ITGA3	1.77e-03	199	37	4	M7253
Pathway	REACTOME_METAL_ION_SLC_TRANSPORTERS	SLC11A2 SLC39A4	1.78e-03	24	37	2	M18795
Pathway	REACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX	CYP4F8 CYP4B1	1.94e-03	25	37	2	MM14858
Pathway	KEGG_MEDICUS_REFERENCE_ITGA_B_FAK_CDC42_SIGNALING_PATHWAY	ITGA10 ITGA3	2.09e-03	26	37	2	M47719
Pathway	WP_INTEGRINMEDIATED_CELL_ADHESION	ITGA10 ITGA3 ITGB2	2.39e-03	102	37	3	M39577
Pathway	WP_INTEGRINMEDIATED_CELL_ADHESION	ITGA10 ITGA3 ITGB2	2.39e-03	102	37	3	MM15830
Pathway	KEGG_MEDICUS_REFERENCE_ITGA_B_RHOG_RAC_SIGNALING_PATHWAY	ITGA10 ITGA3	2.43e-03	28	37	2	M47655
Pathway	REACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS	CYP4F8 CYP4B1 CYP24A1	2.53e-03	104	37	3	M738
Pathway	REACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS	CYP4F8 CYP4B1 CYP24A1	2.60e-03	105	37	3	MM14842
Pathway	WP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY	CYP4B1 CYP24A1	2.78e-03	30	37	2	MM15866
Pathway	KEGG_MEDICUS_REFERENCE_ITGA_B_TALIN_VINCULIN_SIGNALING_PATHWAY	ITGA10 ITGA3	2.78e-03	30	37	2	M47724
Pathway	KEGG_MEDICUS_REFERENCE_ITGA_B_FAK_RAC_SIGNALING_PATHWAY	ITGA10 ITGA3	2.78e-03	30	37	2	M47718
Pathway	REACTOME_METABOLISM_OF_LIPIDS	CYP4F8 SLC44A1 OXCT1 CYP4B1 INPPL1 CYP24A1 GPAT3	3.14e-03	757	37	7	M27451
Pathway	BIOCARTA_NUCLEARRS_PATHWAY	CYP4B1 CYP24A1	3.36e-03	33	37	2	MM1448
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC9A3 SLC44A1 SLC11A2 SLC39A4	3.38e-03	238	37	4	MM15076
Pathway	BIOCARTA_NUCLEARRS_PATHWAY	CYP4B1 CYP24A1	3.57e-03	34	37	2	M16393
Pathway	WP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY	CYP4B1 CYP24A1	3.78e-03	35	37	2	M39488
Pathway	SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES	FLNA FLNC	3.78e-03	35	37	2	M16801
Pathway	WP_HIPPOMERLIN_SIGNALING_DYSREGULATION	ITGA10 ITGA3 ITGB2	3.87e-03	121	37	3	M39823
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC9A3 SLC44A1 SLC11A2 SLC39A4	3.97e-03	249	37	4	M5988
Pubmed	Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.	FLNA FLNC ITGA3 PLS1 PLS3	9.11e-11	18	58	5	12119179
Pubmed	The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin.	FLNA FLNC INPPL1	1.76e-08	4	58	3	11739414
Pubmed	Organization of the gene (RHCE) encoding the human blood group RhCcEe antigens and characterization of the promoter region.	RHCE RHD	2.73e-06	2	58	2	8188244
Pubmed	E variants found in Japanese and c antigenicity alteration without substitution in the second extracellular loop.	RHCE RHD	2.73e-06	2	58	2	11724987
Pubmed	DCS-1, DCS-2, and DFV share amino acid substitutions at the extracellular RhD protein vestibule.	RHCE RHD	2.73e-06	2	58	2	17900276
Pubmed	RHD and RHCE molecular analysis in weak D blood donors and in patients with Rh antibodies against their own corresponding Rh antigen.	RHCE RHD	2.73e-06	2	58	2	32697929
Pubmed	The Rh blood group system: a review.	RHCE RHD	2.73e-06	2	58	2	10627438
Pubmed	Polymorphisms in the promoter regions of RHD and RHCE genes in the Chinese Han population.	RHCE RHD	2.73e-06	2	58	2	37823181
Pubmed	Sequence diversity of the Rh blood group system in Basques.	RHCE RHD	2.73e-06	2	58	2	30089826
Pubmed	Review: the molecular basis of the Rh blood group phenotypes.	RHCE RHD	2.73e-06	2	58	2	15373666
Pubmed	Intron 4 of the RH Gene in Han Chinese, Tibetan, and Mongol Populations.	RHCE RHD	2.73e-06	2	58	2	26579938
Pubmed	Accurate long-read sequencing allows assembly of the duplicated RHD and RHCE genes harboring variants relevant to blood transfusion.	RHCE RHD	2.73e-06	2	58	2	34968422
Pubmed	Transfusion strategy for weak D Type 4.0 based on RHD alleles and RH haplotypes in Tunisia.	RHCE RHD	2.73e-06	2	58	2	29193104
Pubmed	Regarding the size of Rh proteins.	RHCE RHD	2.73e-06	2	58	2	1898705
Pubmed	PCR screening for common weak D types shows different distributions in three Central European populations.	RHCE RHD	2.73e-06	2	58	2	11161244
Pubmed	RH diversity in Mali: characterization of a new haplotype RHDDIVa/RHCEceTI(D2).	RHCE RHD	2.73e-06	2	58	2	25857637
Pubmed	The low-prevalence Rh antigen STEM (RH49) is encoded by two different RHCEce818T alleles that are often in cis to RHDDOL.	RHCE RHD	2.73e-06	2	58	2	22738288
Pubmed	Multiple Rh messenger RNA isoforms are produced by alternative splicing.	RHCE RHD	2.73e-06	2	58	2	1379850
Pubmed	RHCE variants inherited with altered RHD alleles in Brazilian blood donors.	RHCE RHD	2.73e-06	2	58	2	27111588
Pubmed	Characterization of the mouse Rh blood group gene.	RHCE RHD	2.73e-06	2	58	2	10329015
Pubmed	Alteration of RH gene structure and expression in human dCCee and DCW-red blood cells: phenotypic homozygosity versus genotypic heterozygosity.	RHCE RHD	2.73e-06	2	58	2	8822955
Pubmed	Genetic recombination at the human RH locus: a family study of the red-cell Evans phenotype reveals a transfer of exons 2-6 from the RHD to the RHCE gene.	RHCE RHD	2.73e-06	2	58	2	8808597
Pubmed	Molecular background of Rh D-positive, D-negative, D(el) and weak D phenotypes in Chinese.	RHCE RHD	2.73e-06	2	58	2	12201845
Pubmed	Variant RH alleles and Rh immunisation in patients with sickle cell disease.	RHCE RHD	2.73e-06	2	58	2	24960646
Pubmed	Mapping of two genes encoding isoforms of the actin binding protein ABP-280, a dystrophin like protein, to Xq28 and to chromosome 7.	FLNA FLNC	2.73e-06	2	58	2	7689010
Pubmed	RHCEceMO is frequently in cis to RHDDAU0 and encodes a hr(S) -, hr(B) -, RH:-61 phenotype in black persons: clinical significance.	RHCE RHD	2.73e-06	2	58	2	23772606
Pubmed	Comprehensive phenotypic and molecular investigation of RhD and RhCE variants in Moroccan blood donors.	RHCE RHD	2.73e-06	2	58	2	30418133
Pubmed	A convenient qualitative and quantitative method to investigate RHD-RHCE hybrid genes.	RHCE RHD	2.73e-06	2	58	2	23550903
Pubmed	Molecular cloning and primary structure of the human blood group RhD polypeptide.	RHCE RHD	2.73e-06	2	58	2	1438298
Pubmed	Determination of the N-terminal sequence of human red cell Rh(D) polypeptide and demonstration that the Rh(D), (c), and (E) antigens are carried by distinct polypeptide chains.	RHCE RHD	2.73e-06	2	58	2	3135863
Pubmed	Molecular background of D(C)(e) haplotypes within the white population.	RHCE RHD	2.73e-06	2	58	2	12084172
Pubmed	The analysis of nucleotide substitutions, gaps, and recombination events between RHD and RHCE genes through complete sequencing.	RHCE RHD	2.73e-06	2	58	2	10924335
Pubmed	Sequences and evolution of mammalian RH gene transcripts and proteins.	RHCE RHD	2.73e-06	2	58	2	9811965
Pubmed	A two-locus gene conversion model with selection and its application to the human RHCE and RHD genes.	RHCE RHD	2.73e-06	2	58	2	12857961
Pubmed	Specific amino acid substitutions cause distinct expression of JAL (RH48) and JAHK (RH53) antigens in RhCE and not in RhD.	RHCE RHD	2.73e-06	2	58	2	20233350
Pubmed	Rare RHCE phenotypes in black individuals of Afro-Caribbean origin: identification and transfusion safety.	RHCE RHD	2.73e-06	2	58	2	12393640
Pubmed	Molecular genetic basis of the human Rhesus blood group system.	RHCE RHD	2.73e-06	2	58	2	8220426
Pubmed	Filamin isogene expression during mouse myogenesis.	FLNA FLNC	2.73e-06	2	58	2	10679933
Pubmed	A recombination hot spot in the Rh genes revealed by analysis of unrelated donors with the rare D-- phenotype.	RHCE RHD	2.73e-06	2	58	2	8900235
Pubmed	RHDweak partial 4.0 is associated with an altered RHCEce(48C, 105T, 733G, 744C, 1025T) allele in the Tunisian population.	RHCE RHD	2.73e-06	2	58	2	23742316
Pubmed	Isolation of a new cDNA clone encoding an Rh polypeptide associated with the Rh blood group system.	RHCE RHD	2.73e-06	2	58	2	7916743
Pubmed	A comprehensive survey of both RHD and RHCE allele frequencies in sub-Saharan Africa.	RHCE RHD	2.73e-06	2	58	2	24033223
Pubmed	RHDDOL1 and RHDDOL2 encode a partial D antigen and are in cis with the rare RHCE*ceBI allele in people of African descent.	RHCE RHD	2.73e-06	2	58	2	22690701
Pubmed	No Distinction of Orthology/Paralogy between Human and Chimpanzee Rh Blood Group Genes.	RHCE RHD	2.73e-06	2	58	2	26872772
Pubmed	RHCEceTI encodes partial c and partial e and is often in cis to RHDDIVa.	RHCE RHD	2.73e-06	2	58	2	22804620
Pubmed	A novel structural unit in the N-terminal region of filamins.	FLNA FLNC	2.73e-06	2	58	2	24469451
Pubmed	Intricate combinatorial patterns of exon splicing generate multiple Rh-related isoforms in human erythroid cells.	RHCE RHD	2.73e-06	2	58	2	7789951
Pubmed	Appearance of new tetraspanin genes during vertebrate evolution.	TSPAN31 TSPAN10 TSPAN7	4.92e-06	20	58	3	18291621
Pubmed	Assignment of the human genes for desmocollin 3 (DSC3) and desmocollin 4 (DSC4) to chromosome 18q12.	DSC2 DSC3	8.19e-06	3	58	2	7774948
Pubmed	Filamins as integrators of cell mechanics and signalling.	FLNA FLNC	8.19e-06	3	58	2	11252955
Pubmed	The F-actin cross-linking and focal adhesion protein filamin A is a ligand and in vivo substrate for protein kinase C alpha.	FLNA FLNC	8.19e-06	3	58	2	12704190
Pubmed	Generation and characterisation of Rhd and Rhag null mice.	RHCE RHD	8.19e-06	3	58	2	19807729
Pubmed	Involvement of alpha3 integrin/tetraspanin complexes in the angiogenic response induced by angiotensin II.	TSPAN7 ITGA3	8.19e-06	3	58	2	11387256
Pubmed	Sequential expression and differential localization of I-, L-, and T-fimbrin during differentiation of the mouse intestine and yolk sac.	PLS1 PLS3	8.19e-06	3	58	2	7655078
Pubmed	The Roles of Actin-Binding Domains 1 and 2 in the Calcium-Dependent Regulation of Actin Filament Bundling by Human Plastins.	PLS1 PLS3	8.19e-06	3	58	2	28694070
Pubmed	cDNA cloning and expression of a novel human desmocollin.	DSC2 DSC3	8.19e-06	3	58	2	7929347
Pubmed	Hydrophobic cluster analysis and modeling of the human Rh protein three-dimensional structures.	RHCE RHD	8.19e-06	3	58	2	16584906
Pubmed	Evolutionary history of the Rh blood group-related genes in vertebrates.	RHCE RHD	8.19e-06	3	58	2	10970100
Pubmed	Indications for a novel muscular dystrophy pathway. gamma-filamin, the muscle-specific filamin isoform, interacts with myotilin.	FLNA FLNC	8.19e-06	3	58	2	11038172
Pubmed	Human plastin genes. Comparative gene structure, chromosome location, and differential expression in normal and neoplastic cells.	PLS1 PLS3	8.19e-06	3	58	2	8428952
Pubmed	Structure and function of desmosomal proteins and their role in development and disease.	DSC2 DSC3	8.19e-06	3	58	2	14523549
Pubmed	Conserved evolution of the Rh50 gene compared to its homologous Rh blood group gene.	RHCE RHD	8.19e-06	3	58	2	9705835
Pubmed	Desmocollin switching in colorectal cancer.	DSC2 DSC3	8.19e-06	3	58	2	17088906
Pubmed	LL5beta directs the translocation of filamin A and SHIP2 to sites of phosphatidylinositol 3,4,5-triphosphate (PtdIns(3,4,5)P3) accumulation, and PtdIns(3,4,5)P3 localization is mutually modified by co-recruited SHIP2.	FLNA INPPL1	8.19e-06	3	58	2	20236936
Pubmed	Localization and enhanced current density of the Kv4.2 potassium channel by interaction with the actin-binding protein filamin.	FLNA FLNC	8.19e-06	3	58	2	11102480
Pubmed	Filamin A negatively regulates the transcriptional activity of p73alpha in the cytoplasm.	FLNA FLNC	8.19e-06	3	58	2	17825253
Pubmed	Molecular cloning and characterization of plastin, a human leukocyte protein expressed in transformed human fibroblasts.	PLS1 PLS3	8.19e-06	3	58	2	3211125
Pubmed	Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.	FLNA FLNC	8.19e-06	3	58	2	12393796
Pubmed	The members of the RH gene family (RH50 and RH30) followed different evolutionary pathways.	RHCE RHD	8.19e-06	3	58	2	9929383
Pubmed	Cytoskeletal protein ABP-280 directs the intracellular trafficking of furin and modulates proprotein processing in the endocytic pathway.	FLNA FLNC	8.19e-06	3	58	2	9412467
Pubmed	The influence of desmocollin 1-3 expression on prognosis after curative resection of colorectal liver metastases.	DSC2 DSC3	8.19e-06	3	58	2	23975055
Pubmed	Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family.	FLNA FLNC	8.19e-06	3	58	2	11153914
Pubmed	Protein-sequence studies on Rh-related polypeptides suggest the presence of at least two groups of proteins which associate in the human red-cell membrane.	RHCE RHD	8.19e-06	3	58	2	3146980
Pubmed	Compositionally different desmosomes in the various compartments of the human hair follicle.	DSC2 DSC3	8.19e-06	3	58	2	9810708
Pubmed	Changing pattern of desmocollin 3 expression accompanies epidermal organisation during skin development.	DSC2 DSC3	8.19e-06	3	58	2	9389456
Pubmed	Perlecan regulates pericyte dynamics in the maintenance and repair of the blood-brain barrier.	ITGA10 ITGA3 ITGB2	1.25e-05	27	58	3	31541017
Pubmed	Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.	PSME4 INPPL1 CYP24A1 EIF2AK4 ITGA3	1.40e-05	183	58	5	31932471
Pubmed	Microglia/macrophage-specific protein Iba1 binds to fimbrin and enhances its actin-bundling activity.	PLS1 PLS3	1.64e-05	4	58	2	14756805
Pubmed	The sarcomeric Z-disc component myopodin is a multiadapter protein that interacts with filamin and alpha-actinin.	FLNA FLNC	1.64e-05	4	58	2	20554076
Pubmed	Differential localization of villin and fimbrin during development of the mouse visceral endoderm and intestinal epithelium.	PLS1 PLS3	1.64e-05	4	58	2	2686960
Pubmed	Entire sequence of a mouse chromosomal segment containing the gene Rhced and a comparative analysis of the homologous human sequence.	RHCE RHD	1.64e-05	4	58	2	12459264
Pubmed	Structural interaction and functional regulation of polycystin-2 by filamin.	FLNA FLNC	1.64e-05	4	58	2	22802962
Pubmed	Nephrin regulates lamellipodia formation by assembling a protein complex that includes Ship2, filamin and lamellipodin.	FLNA INPPL1	1.64e-05	4	58	2	22194892
Pubmed	Plakoglobin as a regulator of desmocollin gene expression.	DSC2 DSC3	1.64e-05	4	58	2	23652796
Pubmed	HLA-DRB1 molecules and the presentation of anchor peptides from RhD, RhCE, and KEL proteins.	RHCE RHD	1.64e-05	4	58	2	33675036
Pubmed	Association between ABO, Rhesus blood group systems and haemoglobin genotype among confirmed HIV/AIDS-TB co-infected patients in Enugu Urban, Nigeria.	RHCE RHD	1.64e-05	4	58	2	16722361
Pubmed	RHCE represents the ancestral RH position, while RHD is the duplicated gene.	RHCE RHD	2.72e-05	5	58	2	11902138
Pubmed	Evolutionary conservation and diversification of Rh family genes and proteins.	RHCE RHD	2.72e-05	5	58	2	16227429
Pubmed	Loss of desmocollin 1-3 and homeobox genes PITX1 and CDX2 are associated with tumor progression and survival in colorectal carcinoma.	DSC2 DSC3	2.72e-05	5	58	2	22438068
Pubmed	HIV infection of T cells: actin-in and actin-out.	FLNA FLNC	2.72e-05	5	58	2	19366992
Pubmed	Identification and characterization of multiple similar ligand-binding repeats in filamin: implication on filamin-mediated receptor clustering and cross-talk.	FLNA ITGB2	2.72e-05	5	58	2	19828450
Pubmed	Nephrocystin-conserved domains involved in targeting to epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity.	FLNA FLNC	2.72e-05	5	58	2	12006559
Pubmed	Chromosomal assignment of the human genes coding for the major proteins of the desmosome junction, desmoglein DGI (DSG), desmocollins DGII/III (DSC), desmoplakins DPI/II (DSP), and plakoglobin DPIII (JUP).	DSC2 DSC3	2.72e-05	5	58	2	1889810
Pubmed	Nomenclature of the desmosomal cadherins.	DSC2 DSC3	2.72e-05	5	58	2	8486729
Pubmed	Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development.	FLNA FLNC	2.72e-05	5	58	2	17360453
Pubmed	Cytoplasmic domains of the transporter associated with antigen processing and P-glycoprotein interact with subunits of the proteasome.	ABCB5 TAP2	4.08e-05	6	58	2	15488952
Pubmed	Actin-binding protein-280 binds the stress-activated protein kinase (SAPK) activator SEK-1 and is required for tumor necrosis factor-alpha activation of SAPK in melanoma cells.	FLNA FLNC	4.08e-05	6	58	2	9006895
Pubmed	Uropod elongation is a common final step in leukocyte extravasation through inflamed vessels.	ITGA3 ITGB2	4.08e-05	6	58	2	22711877
Pubmed	Ahch, the mouse homologue of DAX1: cloning, characterization and synteny with GyK, the glycerol kinase locus.	FLNA GNRH1	4.08e-05	6	58	2	8921887
Pubmed	Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation.	FLNA FLNC	4.08e-05	6	58	2	12679033
Cytoband	1p36.11	IFNLR1 RHCE RHD	9.05e-05	68	58	3	1p36.11
Cytoband	18q12.1	DSC2 DSC3	5.00e-04	26	58	2	18q12.1
GeneFamily	CD molecules\|Tetraspanins	TSPAN31 TSPAN10 TSPAN7	5.23e-05	33	40	3	768
GeneFamily	Desmosomal cadherins	DSC2 DSC3	9.95e-05	7	40	2	1188
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	SLC44A1 TSPAN7 ITGA3 ITGB2 RHCE RHD	2.11e-04	394	40	6	471
GeneFamily	Solute carriers	SLC9A3 SLC44A1 SLC11A2 SLC39A4 SLC12A8 SLC35F4	2.14e-04	395	40	6	752
GeneFamily	ATP binding cassette subfamily B	ABCB5 TAP2	2.59e-04	11	40	2	806
GeneFamily	CD molecules\|Integrin alpha subunits	ITGA10 ITGA3	7.14e-04	18	40	2	1160
GeneFamily	Cytochrome P450 family 4	CYP4F8 CYP4B1	2.87e-03	36	40	2	1003
GeneFamily	Glycosyltransferase family 6\|Blood group antigens	RHCE RHD	3.03e-03	37	40	2	454
GeneFamily	EF-hand domain containing	TBC1D9B PLS1 PLS3	1.25e-02	219	40	3	863
Coexpression	MILI_PSEUDOPODIA_HAPTOTAXIS_DN	FLNA FLNC CYP4F8 DPY19L3 SLC11A2 TSPAN31 TM2D3 ITGA3 TMEM109	1.51e-05	681	57	9	M5314
Coexpression	FEKIR_HEPARG_SIDE_POP_VS_HEPARG_UP	FLNA GPAT3 ITGA3 GNRH1	4.47e-05	90	57	4	M48360
Coexpression	HALLMARK_APICAL_JUNCTION	FLNC DSC3 INPPL1 ITGA10 ITGA3	7.46e-05	200	57	5	M5915
Coexpression	GSE17186_NAIVE_VS_CD21LOW_TRANSITIONAL_BCELL_CORD_BLOOD_DN	SLC44A1 TSPAN31 INPPL1 ITGB2 PLS3	7.46e-05	200	57	5	M7177
Coexpression	GSE21670_UNTREATED_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_UP	FLNA TMEM144 SLC44A1 GPAT3 ITGB2	7.46e-05	200	57	5	M7457
Coexpression	BROWNE_HCMV_INFECTION_48HR_DN	FLNA TBC1D9B ATP2C1 TSPAN31 ITGA3 TMEM109 ITGB2	8.13e-05	482	57	7	M12144
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Spp1_(Entopeduncular_Nucleus_(Ent)_or_Zona_Incerta,_ventral_part_(ZIV)._State_signal?)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ABCB5 ADGRD1 IFNLR1 RHD	7.49e-07	54	58	4	98b31718fa200432cf86b59a52484da101219f96
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Spp1_(Entopeduncular_Nucleus_(Ent)_or_Zona_Incerta,_ventral_part_(ZIV)._State_signal?)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ABCB5 ADGRD1 IFNLR1 RHD	7.49e-07	54	58	4	872e7374dac64be2c8ebe71e88a2ec6814168d89
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Tmem132c_(SN/VTA_(SNr))--\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CYP4B1 PPP1R3F ADGRF1 GNRH1	1.40e-06	63	58	4	e1b68ef6123ad084ce602b09fd1ba394785797e5
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Tmem132c_(SN/VTA_(SNr))\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CYP4B1 PPP1R3F ADGRF1 GNRH1	1.40e-06	63	58	4	9bfd9ba1335a155ed9e56dd41dd3621b37d4234e
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Tmem132c_(SN/VTA_(SNr))-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CYP4B1 PPP1R3F ADGRF1 GNRH1	1.40e-06	63	58	4	9a90c761898618fc7e5e2984baa1021b74d4ac39
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA FLNC PTCHD1 GLIPR1L2 SLC35F4	3.35e-06	176	58	5	a8875b4ba4abf6625cdeb67bf544ce1573c59060
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ABCB5 PLS3 ADGRD1 IFNLR1 SLC35F4	3.54e-06	178	58	5	e86ed30652c2de70f16430f04b78789b87df4af2
ToppCell	(7)_Epithelial-H_(AT1)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	TMEM61 DSC2 CYP4B1 CYP24A1 ITGA3	4.16e-06	184	58	5	1f76b37c265b519171b767a52d48f31f0cdc4a3c
ToppCell	367C-Epithelial_cells-Epithelial-H_(AT1)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	TMEM61 DSC3 CYP4B1 ITGA3 PLS1	4.62e-06	188	58	5	61422c7919ca0ea02d6be4302f11b169a3ce35e5
ToppCell	367C-Epithelial_cells-Epithelial-H_(AT1)\|367C / Donor, Lineage, Cell class and subclass (all cells)	TMEM61 DSC3 CYP4B1 ITGA3 PLS1	4.62e-06	188	58	5	18698f0b22ccbc2b93759acc1c8dbdb30a6b5a16
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	OXCT1 TMEM61 TSPAN7 GPAT3 ADGRF1	5.52e-06	195	58	5	f7d9adadd37209ce1a38e5d621607b9c9270fed8
ToppCell	Bronchial-10x5prime-Hematologic-Erythrocyte\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	C3orf80 STKLD1 RHCE RHD	2.21e-05	126	58	4	65c7c0e4cfb5ac58d80b4034d42e9f662116e0d3
ToppCell	Bronchial-10x5prime-Hematologic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	C3orf80 STKLD1 RHCE RHD	2.21e-05	126	58	4	b6482ef18e6d9e12ba4810ce7845f9f991cb95bc
ToppCell	Bronchial-10x5prime-Hematologic-Erythrocyte-Erythrocyte\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	C3orf80 STKLD1 RHCE RHD	2.21e-05	126	58	4	12f3d0f60db462f2a9799b3a06005bc871670760
ToppCell	Cerebellum-Neuronal-Excitatory\|Cerebellum / BrainAtlas - Mouse McCarroll V32	GPAT3 ANO3 SLC35F4 TAFA2	2.35e-05	128	58	4	c30ba14320e9b98c9af9e4cd5a8c55380bb9ffa9
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nxph3-Excitatory_Neuron.Slc17a7-Slc17a6.Nxph3-Cbln2-Kcnh8_(Deep_layer_subiculum)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CWH43 ADGRD1 IFNLR1	5.09e-05	55	58	3	5ce0008811bb696191923de9b34ea6e0d8d39a7a
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	OXCT1 TMEM61 TSPAN7 ADGRF1	6.34e-05	165	58	4	a6c6de17fec678ad0cac3138dde3a14cc39ffd26
ToppCell	368C-Myeloid-Monocyte-CD16+_Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CYP4B1 ITGA3 PLS3 IFNLR1	6.64e-05	167	58	4	dbd2b9f2f4ba7be5fdf8318094e6b078cb1d1c43
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ABCB5 PLS3 ADGRD1 SLC35F4	6.96e-05	169	58	4	f47c4fbdc2a38745ec1b35104b85121c1413875a
ToppCell	368C-Myeloid-Monocyte-CD16+_Monocyte\|Monocyte / Donor, Lineage, Cell class and subclass (all cells)	CYP4B1 ITGA3 PLS3 IFNLR1	7.12e-05	170	58	4	4a19c7e3bb0f9c2601a10debe7000066789b4150
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM61 TSPAN7 GPAT3 ADGRF1	7.12e-05	170	58	4	3229f2a02bfa075aa61118552d0407fc018ab3d1
ToppCell	droplet-Kidney-nan-21m\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OXCT1 CYP24A1 TSPAN7 G6PC1	8.14e-05	176	58	4	0475db3f860de1e216cbdeb886f7a75b9f4fc801
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4B1 TSPAN7 ADGRF1 PLS3	8.14e-05	176	58	4	7292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4B1 TSPAN7 ADGRF1 PLS3	8.14e-05	176	58	4	88ca2f83d8301633232735f39b0683efe49d0b86
ToppCell	facs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l7\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DSC3 PCDHGA12 CYP4B1 TSPAN7	8.51e-05	178	58	4	a3f95f0002f408b5b6c57e28b297b5b2737e919c
ToppCell	droplet-Fat-Bat-18m-Endothelial-endothelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4B1 TSPAN7 EIF2AK4 PLS3	8.69e-05	179	58	4	e6224864eb76a2e9c1fc0c61513d9e936bb5c72c
ToppCell	droplet-Fat-Bat-18m-Endothelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4B1 TSPAN7 EIF2AK4 PLS3	8.69e-05	179	58	4	9863ab3ceb160a4b1d9790033a4ac48845863d65
ToppCell	droplet-Fat-Bat-18m-Endothelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4B1 TSPAN7 EIF2AK4 PLS3	8.69e-05	179	58	4	dfe110add7228cd834b35916cbcc849769a01bb9
ToppCell	IPF-Epithelial-Mesothelial\|IPF / Disease state, Lineage and Cell class	FLNC DSC3 SLC12A8 ADGRD1	8.88e-05	180	58	4	1fa54bf4dba72866b2295639d991af639341bc08
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam____podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNC ITGA3 ADGRF1 PLS3	8.88e-05	180	58	4	6327c938a4f99df9fee714e44f15ea4a4a63ae15
ToppCell	cellseq2-Epithelial-Epithelial_Airway-Basal/Suprabasal-Suprabasal\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DSC3 CYP4B1 CYP24A1 ADGRF1	8.88e-05	180	58	4	535a890bde0d978b461c2d4c571529b585c76b21
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GPAT3 EIF2AK4 TMEM109 ITGB2	9.07e-05	181	58	4	c8286a7ac8e3cc5aa7e92b043a08435294ea686f
ToppCell	B_cells-ABCs\|B_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	DSC2 SLC12A8 ITGB2 IFNLR1	9.47e-05	183	58	4	bf9c6fe3ce4e44e4056027257eab8448c39c4fb8
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA PTCHD1 MDGA2 ANO3	9.47e-05	183	58	4	667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM61 TSPAN7 GPAT3 ADGRF1	9.67e-05	184	58	4	282118f8221fa383ffb81dfb5798a0b7f065f911
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CYP4B1 SLC12A8 ITGA3 PLS3	9.87e-05	185	58	4	1c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPY19L3 MDGA2 ANO3 STRIP1	9.87e-05	185	58	4	554c5d812197fbf66bf279fcc953277e926ade15
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DSC3 CYP4B1 TSPAN7 ITGA3	9.87e-05	185	58	4	492529121cb9e88bd3c0db6b54af3cd2979572bc
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Macroglial-oligodendrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC9A3 SLC44A1 PLS1 RHD	9.87e-05	185	58	4	7406a9fdd5beb2777a9cad3268673977bb19f050
ToppCell	Epithelial-alveolar_epithelial_cell_type_1\|World / Lineage, Cell type, age group and donor	CYP4B1 SLC12A8 ITGA3 PLS3	1.01e-04	186	58	4	09d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	OXCT1 TMEM61 TSPAN7 ADGRF1	1.03e-04	187	58	4	7b0168bdaa7c6c6b39878aff6a17f0943189a380
ToppCell	COVID-19-Epithelial_cells-Airway_basal\|COVID-19 / group, cell type (main and fine annotations)	DSC3 CYP4B1 CYP24A1 ITGA3	1.03e-04	187	58	4	8407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA PTCHD1 MDGA2 ANO3	1.05e-04	188	58	4	b2d68a32314e9b099ed74d974079ad96359d1ae3
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	FLNA PTCHD1 PLS3 SLC35F4	1.05e-04	188	58	4	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SLC44A1 SLC11A2 CWH43 ADGRF1	1.05e-04	188	58	4	58ccb31cdf43167872ef0fc737e6f9c51ee2e060
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DSC3 CYP4B1 TSPAN7 ITGA3	1.05e-04	188	58	4	9655a4c47b644a870017d349b99063e17dbae572
ToppCell	droplet-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4B1 TSPAN7 ITGA3 PLS3	1.07e-04	189	58	4	7b6cb745c0a637d6addc105a79059ed488fced39
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	FLNA PTCHD1 PLS3 SLC35F4	1.07e-04	189	58	4	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA PTCHD1 ANO3 ADGRD1	1.09e-04	190	58	4	2e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCell	IPF-Epithelial-Basal\|IPF / Disease state, Lineage and Cell class	DSC3 CYP24A1 ITGA3 PLS3	1.09e-04	190	58	4	ea19e9ce954f2dfde97388db9695325cd92ab88f
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	OXCT1 TMEM61 GPAT3 ADGRF1	1.09e-04	190	58	4	bb3b396d78887d5d6f93a05c8ed4d703591bf33f
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA PTCHD1 ANO3 ADGRD1	1.09e-04	190	58	4	0028f886c789ba238c031eae5d96acaed4af8c25
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ABCB5 TSPAN7 PLS3 SLC35F4	1.12e-04	191	58	4	764c3a8829ae1253a0790744138266e81fc075ec
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA MDGA2 ANO3 ADGRD1	1.12e-04	191	58	4	04c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	OXCT1 TMEM61 TSPAN7 ADGRF1	1.12e-04	191	58	4	feec8617678b778475747ad406c80231e07fd6f7
ToppCell	wk_08-11-Mesenchymal-Mesothelial-intermediate_mesothelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	DSC3 CYP4B1 TSPAN7 ITGA3	1.14e-04	192	58	4	ac9e5288ecd4b1e142f2e15a1fcd11c8eb9e15cd
ToppCell	IPF-Epithelial-Basal\|World / Disease state, Lineage and Cell class	DSC3 CYP24A1 ITGA3 PLS3	1.14e-04	192	58	4	9b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCell	droplet-Lung-LUNG-30m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4B1 TSPAN7 ITGA3 PLS3	1.14e-04	192	58	4	35f7926628a967f85b26371e795a1b93c6f103ab
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DSC2 ADGRF1 PLS1 ANO3	1.14e-04	192	58	4	4a2c82e7af700ae6f04742027877768b151f5d81
ToppCell	droplet-Fat-Mat-18m-Endothelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4B1 TSPAN7 ITGA3 PLS3	1.16e-04	193	58	4	54024a373e42e1c0bcc327dc084564b83b63a9d4
ToppCell	droplet-Fat-Mat-18m-Endothelial-endothelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4B1 TSPAN7 ITGA3 PLS3	1.16e-04	193	58	4	81d908594d2983ba7e7c1ec25afdde4315d9690e
ToppCell	droplet-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYP4B1 TSPAN7 ITGA3 PLS3	1.16e-04	193	58	4	25129080f8a40b2988a5d9dfec36ff9e72c27e61
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA FLNC PTCHD1 C3orf80	1.16e-04	193	58	4	0256e8fe4a47f2e2a43ef9d19bfc047d20806d69
ToppCell	droplet-Lung-30m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYP4B1 TSPAN7 ITGA3 PLS3	1.19e-04	194	58	4	cf7f232827945fbafd2c298c08a799ab916c2472
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	OXCT1 TMEM61 TSPAN7 ADGRF1	1.19e-04	194	58	4	6165c00ec06a8393f23b0c62f679c143839b03b1
ToppCell	droplet-Fat-Mat-18m-Endothelial-Cd36+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4B1 TSPAN7 ITGA3 PLS3	1.19e-04	194	58	4	74d0eaa76f6d9af14110dfe5b4bf9751b99ff6e3
ToppCell	Control-cDC-\|Control / Disease condition and Cell class	OXCT1 GPAT3 EIF2AK4 TMEM109	1.21e-04	195	58	4	a2b4d9473eff73f088b247ce43e66f013622471e
ToppCell	(3)_Chondrocytes-(30)_Chondro\|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis	DSC3 CYP4B1 TSPAN7 MDGA2	1.21e-04	195	58	4	f5597d3ed37770c6fa2b339f98a80ac7ecd4f9ff
ToppCell	Control-cDC\|Control / Disease condition and Cell class	OXCT1 GPAT3 EIF2AK4 TMEM109	1.21e-04	195	58	4	b96acdd22dd3885af69328f170ea871a0d570034
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA PTCHD1 ANO3 ADGRD1	1.23e-04	196	58	4	1522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCell	BAL-Severe-Epithelial-Epithelial-transitional_Epi\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CYP4B1 ADGRF1 PLS1 PLS3	1.23e-04	196	58	4	3e99a367b7d817e1f1221450fcec20ad7a7c7a2a
ToppCell	BAL-Severe-Epithelial-Epithelial-transitional_Epi-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CYP4B1 ADGRF1 PLS1 PLS3	1.23e-04	196	58	4	1efacc37bbfbd05b5d4db3dd10f6d9a238d23e31
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA PTCHD1 ANO3 ADGRD1	1.23e-04	196	58	4	1c8294014713684b50885e638668f2ce75f357f0
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DSC2 DSC3 CYP4B1 ITGA3	1.23e-04	196	58	4	ee89f6884aea11aefeaabe043db7f80145dcdf7f
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DSC2 DSC3 CYP4B1 ITGA3	1.23e-04	196	58	4	e75c36cb042342d69a593fb1ce62fab033889871
ToppCell	Severe_COVID-19-Epithelial-transitional_Epi\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	CYP4B1 ADGRF1 PLS1 PLS3	1.26e-04	197	58	4	5ad3cd4c77016e862041baac3076f8cc0f75c417
ToppCell	BAL-Severe-Epithelial-Epithelial-transitional_Epi-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CYP4B1 ADGRF1 PLS1 PLS3	1.26e-04	197	58	4	08b371309cd790b171ed76cabc7d910e71cd2835
ToppCell	normal_Lung-Epithelial_cells-AT1\|Epithelial_cells / Location, Cell class and cell subclass	FLNA CYP4B1 ITGA3 PLS3	1.26e-04	197	58	4	7d19b93d6853828e2a036e37c4887edb1de4503c
ToppCell	ASK440-Epithelial-Type_1\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	DSC2 CYP4B1 ITGA3 PLS3	1.26e-04	197	58	4	782449c522c9e16e72bf999a73090688a3aefe06
ToppCell	BAL-Severe-Epithelial-Epithelial-transitional_Epi\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CYP4B1 ADGRF1 PLS1 PLS3	1.26e-04	197	58	4	9f49feee38647bbf964974aac96fa75602186b5c
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC9A3 SLC39A4 G6PC1 PLS1	1.28e-04	198	58	4	2967fb2d94662997bfe932ac299c80d6f182fb48
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-mature_enterocytic\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC9A3 SLC39A4 G6PC1 PLS1	1.28e-04	198	58	4	8fac96132663f54566136ef54b53684d31dfde32
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-mature_enterocytic\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC9A3 SLC39A4 G6PC1 PLS1	1.28e-04	198	58	4	222a060c2c63d30da34e4b71c37aa27a048d7d09
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC9A3 SLC39A4 G6PC1 PLS1	1.28e-04	198	58	4	c48b3f026b16d48b8eca9f74dc1e3f3f39a89322
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DSC3 CYP4B1 CYP24A1 ITGA3	1.31e-04	199	58	4	94a7867e800df352731796de8c24cba133c29622
ToppCell	Biopsy_IPF-Epithelial-Transitional_AT2\|Biopsy_IPF / Sample group, Lineage and Cell type	CYP4B1 ITGA3 PLS3 ADGRD1	1.31e-04	199	58	4	83ff8b7e472d1212324c05cc719b746d19e5e23b
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Basal_2\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	DSC3 CYP4B1 CYP24A1 ADGRF1	1.33e-04	200	58	4	c7668e26c6b8cfa6d174b0634e43c230425faba9
ToppCell	cellseq2-Epithelial-Epithelial_Glandular-MEC\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FLNA TMEM61 DSC3 PLS3	1.33e-04	200	58	4	53160551d558148d1d80ec87b90dd6be7d36e4c7
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CYP4B1 ADGRF1 PLS1 PLS3	1.33e-04	200	58	4	f386a86b127433cbac306950443355bd723080ff
ToppCell	cellseq2-Epithelial-Epithelial_Glandular-MEC-MEC\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FLNA TMEM61 DSC3 PLS3	1.33e-04	200	58	4	af4d922659b6f9d446797f7a3922a211e22f88e4
ToppCell	Parenchyma_COVID-19-Epithelial-TX-Basal_2\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	DSC3 CYP4B1 CYP24A1 ADGRF1	1.33e-04	200	58	4	bce9bce9eb622bc6514708d49ca4a6604043c22a
ToppCell	343B-Fibroblasts-Fibroblast-K_(Pericytes)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	FLNA ITGA10 ITGA3 PLS3	1.33e-04	200	58	4	4fb6fd703aca9a992924245105ad99163146a415
ToppCell	Bronchial_Brush-Epithelial-Basal_2\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	FLNA DSC3 CYP24A1 PLS3	1.33e-04	200	58	4	1fa29a9f42987549a75dffeb177099458f7cca88
ToppCell	Severe-Epithelial-Epithelial-\|Severe / Condition, Lineage, Cell class and cell subclass	CYP4B1 ADGRF1 PLS1 PLS3	1.33e-04	200	58	4	8669ce08f93eefb8ac970e30cdc4b1f908023c54
ToppCell	Bronchial_Brush-Epithelial-Basal_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	FLNA DSC3 CYP24A1 PLS3	1.33e-04	200	58	4	7595eb2a8af3de879ecaa71f3d96f890e13b59ce
ToppCell	Severe-Epithelial\|Severe / Condition, Lineage, Cell class and cell subclass	CYP4B1 ADGRF1 PLS1 PLS3	1.33e-04	200	58	4	6ead9db88568bb829d564a6d8e85f71fd765bac0
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Mesothelial-1\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	DSC2 DSC3 PLS3 ADGRD1	1.33e-04	200	58	4	c800f20adedf4ca736c740510889e92d8bf0ba44
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Basal_2-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DSC3 CYP4B1 CYP24A1 ADGRF1	1.33e-04	200	58	4	621dd6438ef6e71811d3644b75209535b7c0f8f7
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CYP4B1 ADGRF1 PLS1 PLS3	1.33e-04	200	58	4	b75154417c215b8853186bff46d624ebd387ac4f
ToppCell	Parenchyma_COVID-19-Stromal-TX-Mesothelial-1\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	DSC2 DSC3 PLS3 ADGRD1	1.33e-04	200	58	4	bf50e30d5cafb71c567e89580f62084d2f894170
Computational	Genes in the cancer module 275.	ITGA10 ITGA3 ITGB2	1.44e-05	16	33	3	MODULE_275
Computational	Actin cytoskeleton binding.	FLNA FLNC PLS3	1.01e-04	30	33	3	MODULE_524
Computational	Genes in the cancer module 419.	FLNA FLNC PLS3	1.48e-04	34	33	3	MODULE_419
Computational	Genes in the cancer module 412.	ITGA3 ITGB2	6.98e-04	13	33	2	MODULE_412
Drug	N-methylformamide	ABCB5 ITGA10 ITGA3 ITGB2 GNRH1	7.14e-07	66	58	5	CID000031254
Drug	AC1L1KIN	CYP4F8 CYP4B1 ABCB5 CYP24A1 GNRH1	5.63e-06	100	58	5	CID000005516
Disease	Anemia, Hemolytic, Congenital	RHCE RHD	3.67e-06	2	57	2	C0002881
Disease	myofibrillar myopathy 5 (implicated_via_orthology)	FLNA FLNC	1.10e-05	3	57	2	DOID:0080096 (implicated_via_orthology)
Disease	Rh Deficiency Syndrome	RHCE RHD	1.10e-05	3	57	2	C0272052
Disease	distal muscular dystrophy 4 (implicated_via_orthology)	FLNA FLNC	1.10e-05	3	57	2	DOID:0111190 (implicated_via_orthology)
Disease	Rh-Null, Regulator Type	RHCE RHD	1.10e-05	3	57	2	C1849387
Disease	arrhythmogenic right ventricular cardiomyopathy (implicated_via_orthology)	DSC2 DSC3	3.65e-05	5	57	2	DOID:0050431 (implicated_via_orthology)
Disease	desmocollin-2 measurement	DSC2 DSC3	3.65e-05	5	57	2	EFO_0021936
Disease	macrophage migration inhibitory factor measurement	MDGA2 ADGRD1 TAFA2	7.98e-05	43	57	3	EFO_0008221
Disease	bronchopulmonary dysplasia	DSC2 DSC3 MDGA2	9.15e-05	45	57	3	MONDO_0019091
Disease	pneumonia (implicated_via_orthology)	SLC11A2 ITGB2	1.63e-04	10	57	2	DOID:552 (implicated_via_orthology)
Disease	Mental Retardation, X-Linked 1	PTCHD1 TSPAN7	1.75e-03	32	57	2	C2931498
Disease	Huntington's disease (implicated_via_orthology)	PLS1 PLS3	1.75e-03	32	57	2	DOID:12858 (implicated_via_orthology)
Disease	age of onset of Alzheimer disease	ATP2C1 ANO3	1.86e-03	33	57	2	OBA_2001000

Protein segments in the cluster

Peptide	Gene	Start	Entry
GKKGDVWRLGLLLLS	EIF2AK4	476	Q9P2K8
KAVGEILLLPGWIAL	ADGRD1	326	Q6QNK2
KSLLILTPLLGLTWG	ADGRF1	791	Q5T601
LAVGLVKGWKLTLVT	ABCB5	196	Q2M3G0
LWKILSLTIGGTIAL	DPY19L3	41	Q6ZPD9
LLWEGGLIKVELCRG	CFAP44	346	Q96MT7
QLGKWAILAILLGIA	DSC2	691	Q02487
IIGIIMLVGWLLGKD	ATP2C1	276	P98194
IWLGILEGIGILAVI	ANO3	811	Q9BYT9
KGLVLLGILLGTLWE	PCDHGA12	11	O60330
LILLLVIAAGGVIWK	IFNLR1	236	Q8IU57
GGVLKLRLCELWLLL	GLIPR1L2	21	Q4G1C9
VLGLLWQIIKVGLFA	PLS1	226	Q14651
LVLGLLWQIIKIGLF	PLS3	226	P13797
EGLVGLGTLVLGLEW	ITGA3	806	P26006
AIVDGNLKLILGLIW	FLNC	121	Q14315
GFKLLWILLLATLVG	SLC11A2	101	P49281
GLVWLLTVLLEGISG	MDGA2	6	Q7Z553
PVGLEGLLTTKWLLR	ALDH18A1	751	P54886
GIVLIGILLLVIWKA	ITGB2	711	P05107
EGVIGCLDLILKWLT	CKAP5	1236	Q14008
VILGKWAILAILLGI	DSC3	686	Q14574
LLGSLLQILWKGGLK	CYP24A1	66	Q07973
LAGKILSTWLTLVLG	GPAT3	6	Q53EU6
DGNLKLILGLIWTLI	FLNA	131	P21333
LLKGLGVDLLWTLEK	G6PC1	226	P35575
KTLKPWLGDGLLLSV	CYP4F8	126	P98187
GWFVRKLSGLLILLV	C3orf80	76	F5H4A9
ISLWILIGSVLGGLL	ITGA10	1121	O75578
VWILTILVILGSLGG	SLC44A1	241	Q8WWI5
WASGLILVLGFLKLI	CYP4B1	16	P13584
KLLAGLILLTWCVEG	GNRH1	6	P01148
LALLGINLAGVKWII	SLC12A8	166	A0AV02
FLWLLVGVGLLGLGL	CWH43	396	Q9H720
KGKLLIIIFIVTLWG	TAFA2	11	Q8N3H0
GLILIEKELAELGWK	TCP11X2	356	Q5H9J9
KPWLGLLGLVTISLA	PTCHD1	296	Q96NR3
ALLIVLGLVLGGIVW	SLC9A3	86	P48764
VGLLGGWTVLLLLSL	SLC39A4	626	Q6P5W5
VLLLLWKTVLCTLGG	STRIP1	286	Q5VSL9
WLDLLRGGLKELTDL	INPPL1	481	O15357
EGTLRLGGLWGLLKL	TAP2	41	Q03519
KKGLTLIELWEGLTV	OXCT1	481	P55809
VLKGIWGLLIILSVS	SLC35F4	161	A4IF30
LKGIPESLRGELWLL	TBC1D9B	506	Q66K14
AGGLLLLIGLLWSVK	TMEM61	76	Q8N0U2
LLIGLLWSVKASIPG	TMEM61	81	Q8N0U2
GLLTGLLLNLKIWKA	RHD	381	Q02161
GLLTGLLLNLKIWKA	RHCE	381	P18577
GLGLLWALLLDGIIV	STKLD1	481	Q8NE28
IKTIGLGLGILIWGS	TMEM144	86	Q7Z5S9
LLIGVAAWGKGLGLV	TSPAN31	26	Q12999
LGILTDRDLILKWPG	PPP1R3F	526	Q6ZSY5
WKFEHIGIGLLSLLL	PSME4	1161	Q14997
LVLALLGRILWGLKL	TMEM109	151	Q9BVC6
LGRILWGLKLVIFLA	TMEM109	156	Q9BVC6
GLLALAIGLWGLAVK	TSPAN10	91	Q9H1Z9
VILLAVGVWGKLTLG	TSPAN7	31	P41732
GLGIWTLIDVLLIGV	TM2D3	221	Q9BRN9
ETLAPSLLLVLKWGG	PPIP5K1	511	Q6PFW1
SLLLVLKWGGELTPA	PPIP5K1	516	Q6PFW1