Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	P-type potassium:proton transporter activity	ATP4A ATP4B	5.36e-05	3	85	2	GO:0008900
GeneOntologyBiologicalProcess	pH reduction	TCIRG1 ATP4A ATP4B	2.25e-06	7	84	3	GO:0045851
GeneOntologyCellularComponent	potassium:proton exchanging ATPase complex	ATP4A ATP4B	4.55e-05	3	82	2	GO:0005889
Domain	Sec7_N	GBF1 ARFGEF2	1.11e-04	4	81	2	IPR032691
Domain	Sec7_N	GBF1 ARFGEF2	1.11e-04	4	81	2	PF12783
Domain	Anaphylatoxin_comp_syst	C4A C4B	1.84e-04	5	81	2	IPR018081
Domain	Anaphylatoxn_comp_syst_dom	C4A C4B	1.84e-04	5	81	2	IPR001840
Domain	ANATO	C4A C4B	3.85e-04	7	81	2	SM00104
Domain	ANATO	C4A C4B	3.85e-04	7	81	2	PF01821
Domain	ANAPHYLATOXIN_2	C4A C4B	3.85e-04	7	81	2	PS01178
Domain	ANAPHYLATOXIN_1	C4A C4B	3.85e-04	7	81	2	PS01177
Domain	Anaphylatoxin/fibulin	C4A C4B	3.85e-04	7	81	2	IPR000020
Domain	Thiol-ester_cl	C4A C4B	5.11e-04	8	81	2	PF10569
Domain	MacrogloblnA2_thiol-ester-bond	C4A C4B	5.11e-04	8	81	2	IPR019565
Domain	MacrogloblnA2_CS	C4A C4B	5.11e-04	8	81	2	IPR019742
Domain	A2M_N	C4A C4B	8.17e-04	10	81	2	PF01835
Domain	A2M_N	C4A C4B	8.17e-04	10	81	2	IPR002890
Domain	A-macroglobulin_rcpt-bd	C4A C4B	8.17e-04	10	81	2	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	C4A C4B	8.17e-04	10	81	2	PS00477
Domain	A2M	C4A C4B	8.17e-04	10	81	2	PF00207
Domain	A2M_N_2	C4A C4B	8.17e-04	10	81	2	IPR011625
Domain	A2M_comp	C4A C4B	8.17e-04	10	81	2	IPR011626
Domain	A2M_N_2	C4A C4B	8.17e-04	10	81	2	PF07703
Domain	A2M_recep	C4A C4B	8.17e-04	10	81	2	PF07677
Domain	A2M_comp	C4A C4B	8.17e-04	10	81	2	PF07678
Domain	Macroglobln_a2	C4A C4B	8.17e-04	10	81	2	IPR001599
Domain	Calpain_III	CAPN9 CAPN10	1.19e-03	12	81	2	IPR022683
Domain	calpain_III	CAPN9 CAPN10	1.19e-03	12	81	2	SM00720
Domain	C2_III	CAPN9 CAPN10	1.19e-03	12	81	2	IPR033883
Domain	Calpain_domain_III	CAPN9 CAPN10	1.40e-03	13	81	2	IPR022682
Domain	Calpain_III	CAPN9 CAPN10	1.40e-03	13	81	2	PF01067
Domain	Calpain_cysteine_protease	CAPN9 CAPN10	1.63e-03	14	81	2	IPR022684
Domain	CysPc	CAPN9 CAPN10	1.88e-03	15	81	2	SM00230
Domain	Peptidase_C2_calpain_cat	CAPN9 CAPN10	1.88e-03	15	81	2	IPR001300
Domain	-	GBF1 ARFGEF2	1.88e-03	15	81	2	1.10.1000.11
Domain	Peptidase_C2	CAPN9 CAPN10	1.88e-03	15	81	2	PF00648
Domain	CALPAIN_CAT	CAPN9 CAPN10	1.88e-03	15	81	2	PS50203
Domain	Sec7	GBF1 ARFGEF2	1.88e-03	15	81	2	PF01369
Domain	Sec7_alpha_orthog	GBF1 ARFGEF2	1.88e-03	15	81	2	IPR023394
Domain	Sec7	GBF1 ARFGEF2	2.14e-03	16	81	2	SM00222
Domain	SEC7	GBF1 ARFGEF2	2.14e-03	16	81	2	PS50190
Domain	Sec7_dom	GBF1 ARFGEF2	2.14e-03	16	81	2	IPR000904
Domain	C345C	C4A C4B	2.42e-03	17	81	2	SM00643
Domain	Terpenoid_cyclase/PrenylTrfase	C4A C4B	2.72e-03	18	81	2	IPR008930
Domain	NTR	C4A C4B	3.03e-03	19	81	2	PF01759
Domain	Netrin_module_non-TIMP	C4A C4B	3.03e-03	19	81	2	IPR018933
Domain	NTR	C4A C4B	4.43e-03	23	81	2	PS50189
Domain	Netrin_domain	C4A C4B	4.43e-03	23	81	2	IPR001134
Domain	TIMP-like_OB-fold	C4A C4B	5.64e-03	26	81	2	IPR008993
Domain	THIOL_PROTEASE_CYS	CAPN9 CAPN10	5.64e-03	26	81	2	PS00139
Domain	THIOL_PROTEASE_ASN	CAPN9 CAPN10	6.08e-03	27	81	2	PS00640
Domain	IPT	PKHD1 PLXND1	6.08e-03	27	81	2	SM00429
Domain	THIOL_PROTEASE_HIS	CAPN9 CAPN10	6.08e-03	27	81	2	PS00639
Domain	Pept_cys_AS	CAPN9 CAPN10	6.53e-03	28	81	2	IPR000169
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	EPN3 MTA2 GBF1 MAP1S ZNF296 LRRC24 NBEAL2 ZNF516 HECTD4 MED14 AKNA ARFGEF2 PPARA PLXND1 AP3D1 DUS1L	9.74e-09	1105	85	16	35748872
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	GBF1 GSE1 MAP1S TCOF1 ZNF516 EIF2B5 MED14 ZNF638 ARFGEF2 LARP1 DIDO1 IQCN MRTFA	5.03e-08	774	85	13	15302935
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	NBEAL2 KIF21A SETBP1 ZNF516 HECTD4 AKNA LARP1 DIDO1 PLXND1 NACAD CAPN10	7.03e-08	529	85	11	14621295
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	FREM2 TBX3 GSE1 EIF2B5 ZNF638 LARP1 DIDO1 C4A C4B AP3D1 PARP12	5.45e-07	650	85	11	38777146
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZNF438 MTA2 TBX3 ZNF296 KLF5 ZNF516 ZNF638 DIDO1 E2F2 PPARA MRTFA PARP12	6.35e-07	808	85	12	20412781
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	GSE1 TCOF1 GPATCH1 EIF2B5 MED14 ZNF638 DIDO1 AP3D1	1.96e-06	341	85	8	32971831
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	MTA2 EMC6 LRRC24 TCOF1 TTLL6 SYNE2 MED14 DCHS1 ZNF638 DIDO1 MRTFA	2.30e-06	754	85	11	35906200
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	LRRC24 TCOF1 KIF21A SYNE2 ZNF516 HECTD4 DCHS1 DIDO1 PPP1R9B GRIN2B PRDX2 BAIAP2	3.90e-06	963	85	12	28671696
Pubmed	Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.	C4A C4B	5.90e-06	2	85	2	22737222
Pubmed	Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.	C4A C4B	5.90e-06	2	85	2	16565498
Pubmed	Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.	C4A C4B	5.90e-06	2	85	2	15998580
Pubmed	Structural polymorphism of murine C4 and its linkage to H-2.	C4A C4B	5.90e-06	2	85	2	7373044
Pubmed	High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.	C4A C4B	5.90e-06	2	85	2	19062096
Pubmed	The chemical structure of the C4d fragment of the human complement component C4.	C4A C4B	5.90e-06	2	85	2	3696167
Pubmed	Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.	C4A C4B	5.90e-06	2	85	2	1357031
Pubmed	Effect of increased bile acid synthesis or fecal excretion in irritable bowel syndrome-diarrhea.	FGFR4 KLB	5.90e-06	2	85	2	25070056
Pubmed	Promiscuous thymic expression of an autoantigen gene does not result in negative selection of pathogenic T cells.	ATP4A ATP4B	5.90e-06	2	85	2	16237067
Pubmed	Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.	C4A C4B	5.90e-06	2	85	2	16098595
Pubmed	Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.	C4A C4B	5.90e-06	2	85	2	19933335
Pubmed	Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.	C4A C4B	5.90e-06	2	85	2	2459207
Pubmed	Antigen-induced B cell apoptosis is independent of complement C4.	C4A C4B	5.90e-06	2	85	2	17645767
Pubmed	Structural organization and transcription of the mouse gastric H+, K(+)-ATPase beta subunit gene.	ATP4A ATP4B	5.90e-06	2	85	2	1654563
Pubmed	Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.	C4A C4B	5.90e-06	2	85	2	15787745
Pubmed	Anti-DNA autoreactivity in C4-deficient mice.	C4A C4B	5.90e-06	2	85	2	12207352
Pubmed	Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.	C4A C4B	5.90e-06	2	85	2	30026462
Pubmed	A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.	C4A C4B	5.90e-06	2	85	2	6559257
Pubmed	Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.	C4A C4B	5.90e-06	2	85	2	27758680
Pubmed	Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.	C4A C4B	5.90e-06	2	85	2	22387014
Pubmed	Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Spectrum Disorder Subjects.	C4A C4B	5.90e-06	2	85	2	34299197
Pubmed	Assessment of complement C4 gene copy number using the paralog ratio test.	C4A C4B	5.90e-06	2	85	2	20506482
Pubmed	Polymerase chain reaction based C4AQ0 and C4BQ0 genotyping: association with systemic lupus erythematosus in southwest Han Chinese.	C4A C4B	5.90e-06	2	85	2	12480675
Pubmed	Low C4, C4A and C4B gene copy numbers are stronger risk factors for juvenile-onset than for adult-onset systemic lupus erythematosus.	C4A C4B	5.90e-06	2	85	2	26800705
Pubmed	Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.	C4A C4B	5.90e-06	2	85	2	23749435
Pubmed	Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.	C4A C4B	5.90e-06	2	85	2	23918728
Pubmed	Murine complement C4 is not required for experimental autoimmune encephalomyelitis.	C4A C4B	5.90e-06	2	85	2	15390104
Pubmed	Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.	C4A C4B	5.90e-06	2	85	2	3037333
Pubmed	Proton pump inhibitors and acid-related diseases.	ATP4A ATP4B	5.90e-06	2	85	2	9017763
Pubmed	Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.	C4A C4B	5.90e-06	2	85	2	11726230
Pubmed	Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.	C4A C4B	5.90e-06	2	85	2	4216347
Pubmed	Importance of the alpha 3-fragment of complement C4 for the binding with C4b-binding protein.	C4A C4B	5.90e-06	2	85	2	1699796
Pubmed	Metabolic regulator betaKlotho interacts with fibroblast growth factor receptor 4 (FGFR4) to induce apoptosis and inhibit tumor cell proliferation.	FGFR4 KLB	5.90e-06	2	85	2	20657013
Pubmed	Sequence determination of the thiolester site of the fourth component of human complement.	C4A C4B	5.90e-06	2	85	2	6950384
Pubmed	Molecular cloning and characterization of complementary and genomic DNA clones for mouse C4 and Slp.	C4A C4B	5.90e-06	2	85	2	2997024
Pubmed	A convenient model of severe, high incidence autoimmune gastritis caused by polyclonal effector T cells and without perturbation of regulatory T cells.	ATP4A ATP4B	5.90e-06	2	85	2	22096532
Pubmed	Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.	C4A C4B	5.90e-06	2	85	2	8660986
Pubmed	Constitutive expression of Slp genes in mouse strain B10.WR directed by C4 regulatory sequences.	C4A C4B	5.90e-06	2	85	2	3624865
Pubmed	Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.	C4A C4B	5.90e-06	2	85	2	8428773
Pubmed	Primary structure and functional expression of the mouse and frog alpha-subunit of the gastric H(+)-K(+)-ATPase.	ATP4A ATP4B	5.90e-06	2	85	2	7762614
Pubmed	Determination of the loss of function complement C4 exon 29 CT insertion using a novel paralog-specific assay in healthy UK and Spanish populations.	C4A C4B	5.90e-06	2	85	2	21857912
Pubmed	Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.	C4A C4B	5.90e-06	2	85	2	24638111
Pubmed	Isolation of cDNA clones specifying the fourth component of mouse complement and its isotype, sex-limited protein.	C4A C4B	5.90e-06	2	85	2	6208559
Pubmed	The role of the histocompatibility-2-linked Ss-Slp region in the control of mouse complement.	C4A C4B	5.90e-06	2	85	2	4514997
Pubmed	Klotho-beta overexpression as a novel target for suppressing proliferation and fibroblast growth factor receptor-4 signaling in hepatocellular carcinoma.	FGFR4 KLB	5.90e-06	2	85	2	22439738
Pubmed	Transcriptional repression of C4 complement by hepatitis C virus proteins.	C4A C4B	5.90e-06	2	85	2	21345967
Pubmed	The inheritance of susceptibility to the Gross leukemia virus in mice.	C4A C4B	5.90e-06	2	85	2	5919331
Pubmed	Pharmacogenetics of the effects of colesevelam on colonic transit in irritable bowel syndrome with diarrhea.	FGFR4 KLB	5.90e-06	2	85	2	22271411
Pubmed	Molecular and cellular regulation of the gastric proton pump.	ATP4A ATP4B	5.90e-06	2	85	2	14743830
Pubmed	An ancient provirus has imposed androgen regulation on the adjacent mouse sex-limited protein gene.	C4A C4B	5.90e-06	2	85	2	3167981
Pubmed	The dichotomous size variation of human complement C4 genes is mediated by a novel family of endogenous retroviruses, which also establishes species-specific genomic patterns among Old World primates.	C4A C4B	5.90e-06	2	85	2	7545960
Pubmed	PPAR alpha mediates transcriptional upregulation of novel organic cation transporters-2 and -3 and enzymes involved in hepatic carnitine synthesis.	SLC22A5 PPARA	5.90e-06	2	85	2	18296741
Pubmed	Insights on the relationship between complement component C4 serum concentrations and C4 gene copy numbers in a Western Australian systemic lupus erythematosus cohort.	C4A C4B	5.90e-06	2	85	2	30041577
Pubmed	Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.	C4A C4B	5.90e-06	2	85	2	2572548
Pubmed	The complement component C4 of mammals.	C4A C4B	5.90e-06	2	85	2	2302180
Pubmed	Complete cDNA sequence of the fourth component of murine complement.	C4A C4B	5.90e-06	2	85	2	3862104
Pubmed	The BS variant of C4 protects against age-related loss of white matter microstructural integrity.	C4A C4B	5.90e-06	2	85	2	34358307
Pubmed	Acute renal allograft rejection: diagnostic significance of focal peritubular capillary C4d.	C4A C4B	5.90e-06	2	85	2	18360261
Pubmed	Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.	C4A C4B	5.90e-06	2	85	2	22151770
Pubmed	C4d-positive chronic rejection: a frequent entity with a poor outcome.	C4A C4B	5.90e-06	2	85	2	18091514
Pubmed	Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.	C4A C4B	5.90e-06	2	85	2	29080553
Pubmed	Schizophrenia risk from complex variation of complement component 4.	C4A C4B	5.90e-06	2	85	2	26814963
Pubmed	Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.	C4A C4B	5.90e-06	2	85	2	6589636
Pubmed	C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.	C4A C4B	5.90e-06	2	85	2	25339671
Pubmed	A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.	C4A C4B	5.90e-06	2	85	2	17728371
Pubmed	Structure and organization of the C4 genes.	C4A C4B	5.90e-06	2	85	2	6149580
Pubmed	Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.	C4A C4B	5.90e-06	2	85	2	6149581
Pubmed	The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.	C4A C4B	5.90e-06	2	85	2	12115608
Pubmed	Biochemistry and biology of anaphylatoxins.	C4A C4B	5.90e-06	2	85	2	3542363
Pubmed	C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.	C4A C4B	5.90e-06	2	85	2	2387317
Pubmed	Promoter elements of the mouse complement C4 gene critical for transcription activation and start site location.	C4A C4B	5.90e-06	2	85	2	8132550
Pubmed	Viperin Targets Flavivirus Virulence by Inducing Assembly of Noninfectious Capsid Particles.	RSAD2 GBF1	5.90e-06	2	85	2	29046456
Pubmed	Substitution of a single amino acid (aspartic acid for histidine) converts the functional activity of human complement C4B to C4A.	C4A C4B	5.90e-06	2	85	2	2395880
Pubmed	Effects of Complement C4 Gene Copy Number Variations, Size Dichotomy, and C4A Deficiency on Genetic Risk and Clinical Presentation of Systemic Lupus Erythematosus in East Asian Populations.	C4A C4B	5.90e-06	2	85	2	26814708
Pubmed	cDNA clone spanning the alpha-gamma subunit junction in the precursor of the murine fourth complement component (C4).	C4A C4B	5.90e-06	2	85	2	6192448
Pubmed	Cardiac Myocyte KLF5 Regulates Ppara Expression and Cardiac Function.	KLF5 PPARA	5.90e-06	2	85	2	26574507
Pubmed	Complete primary structure of human C4a anaphylatoxin.	C4A C4B	5.90e-06	2	85	2	6167582
Pubmed	Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.	C4A C4B	5.90e-06	2	85	2	16908004
Pubmed	Slp is an essential component of an EDTA-resistant activation pathway of mouse complement.	C4A C4B	5.90e-06	2	85	2	1438267
Pubmed	Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.	C4A C4B	5.90e-06	2	85	2	7365238
Pubmed	Human gastric (H+ + K+)-ATPase gene. Similarity to (Na+ + K+)-ATPase genes in exon/intron organization but difference in control region.	ATP4A ATP4B	5.90e-06	2	85	2	2160952
Pubmed	Genetic deficiency of complement isoforms C4A or C4B predicts improved survival of metastatic renal cell carcinoma.	C4A C4B	5.90e-06	2	85	2	19150565
Pubmed	Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.	C4A C4B	5.90e-06	2	85	2	7391573
Pubmed	Elevated levels of endogenous apoptotic DNA and IFN-alpha in complement C4-deficient mice: implications for induction of systemic lupus erythematosus.	C4A C4B	5.90e-06	2	85	2	17506029
Pubmed	Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.	C4A C4B	5.90e-06	2	85	2	17971360
Pubmed	Low C4 gene copy numbers are associated with superior graft survival in patients transplanted with a deceased donor kidney.	C4A C4B	5.90e-06	2	85	2	23715124
Pubmed	Identification of the 5'-flanking regulatory region responsible for the difference in transcriptional control between mouse complement C4 and Slp genes.	C4A C4B	5.90e-06	2	85	2	3464002
Pubmed	Complete nucleotide and derived amino acid sequences of the fourth component of mouse complement (C4). Evolutionary aspects.	C4A C4B	5.90e-06	2	85	2	2993295
Pubmed	Clinical features of patients with homozygous complement C4A or C4B deficiency.	C4A C4B	5.90e-06	2	85	2	29928053
Pubmed	Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.	C4A C4B	5.90e-06	2	85	2	17971229
Pubmed	Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease. Genetic and immunologic studies.	C4A C4B	5.90e-06	2	85	2	6881182
Pubmed	Identification of the site of sulfation of the fourth component of human complement.	C4A C4B	5.90e-06	2	85	2	3944109
GeneFamily	ATPase H+/K+ transporting	ATP4A ATP4B	2.43e-05	3	52	2	1211
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C4A C4B	2.88e-04	9	52	2	1234
GeneFamily	C2 domain containing\|Calpains	CAPN9 CAPN10	8.32e-04	15	52	2	975
Coexpression	GSE6269_FLU_VS_E_COLI_INF_PBMC_UP	UBA7 RSAD2 GSE1 NBEAL2 LARP1 AP3D1 MRTFA PARP12	5.76e-08	164	84	8	M5653
Coexpression	GSE360_HIGH_VS_LOW_DOSE_B_MALAYI_DC_UP	COMP ACO1 ZNF516 LTBP1 BAIAP2 ATP4B SDR39U1	3.50e-06	198	84	7	M5222
Coexpression	DESCARTES_FETAL_STOMACH_PARIETAL_AND_CHIEF_CELLS	EPN3 GPT2 ATP4A ATP4B	1.00e-05	42	84	4	M40300
Coexpression	GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP	UBA7 RSAD2 NMI COMP ZNF296 KLF5 NBEAL2 TCIRG1 C4A C4B FGFR4 BAIAP2 PARP12 CAPN10	3.30e-05	1226	84	14	MM979
Coexpression	LEE_TARGETS_OF_PTCH1_AND_SUFU_UP	AKNA C4A C4B CAVIN2	4.17e-05	60	84	4	MM601
Coexpression	GSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_TCELL_MEMBRANES_ACT_MAST_CELL_UP	UBA7 RSAD2 NMI MAP1S TCIRG1 PARP12	4.54e-05	200	84	6	M7320
Coexpression	GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP	UBA7 RSAD2 NMI COMP ZNF296 KLF5 NBEAL2 TCIRG1 C4B FGFR4 BAIAP2 PARP12 CAPN10	7.27e-05	1151	84	13	M1103
CoexpressionAtlas	BM Top 100 - urethra	COL6A3 SCGB3A1 COMP KLF5 ITGA8	1.14e-05	77	81	5	BM Top 100 - urethra
CoexpressionAtlas	kidney_e15.5_SmlBldVes_Tie2_k-means-cluster#2_top-relative-expression-ranked_200	RSAD2 NMI PLXND1 F8 CAVIN2	3.49e-05	97	81	5	gudmap_kidney_e15.5_SmlBldVes_Tie2_k2_200
ToppCell	Control-Control-Lymphocyte-T/NK-NK_activated\|Control / Disease, condition lineage and cell class	COL6A3 RSAD2 SETBP1 SYNE2 BRME1 AKNA PARP12	1.06e-07	198	85	7	76d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCell	T_cells-ISG-high_CD4+_T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	UBA7 RSAD2 NMI KLF5 SYNE2 PARP12	1.63e-06	188	85	6	6f8946d4710f6e32c937213f99b790b098b8819c
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A3 TBX3 COMP SETBP1 ITGA8 LTBP1	2.14e-06	197	85	6	44673c38384453207871d3fd8e8ba9093cc06bc5
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	EPN3 NBEAL2 SYNE2 PKHD1 BAIAP2 CAVIN2	2.27e-06	199	85	6	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	NBEAL2 KIF21A SYNE2 PKHD1 BAIAP2 CAVIN2	2.34e-06	200	85	6	ddfb1f006365bf16203ee49f20200f68220cc288
ToppCell	facs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l7\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RSAD2 GRIN2B PLXND1 TMPRSS11F CAVIN2	1.31e-05	158	85	5	78b48b110b777bcc4c07cd23388bee911c0231d6
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ACO1 SLC22A5 PPARA BAIAP2 GPT2	2.03e-05	173	85	5	8888434641ea554a9b62c436e87920378eef29cd
ToppCell	3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SCGB3A1 GRIN2B PLXND1 F8 CAVIN2	2.20e-05	176	85	5	5d3b2395bb842eea39175f5af6a4c76527e2fc31
ToppCell	T_cells-ISG-high_CD4+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	UBA7 RSAD2 NMI KLF5 PARP12	2.39e-05	179	85	5	af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ACO1 SLC22A5 PPARA BAIAP2 GPT2	2.39e-05	179	85	5	78fae47ec9bff4e0159a86a281e831d7f8ee925a
ToppCell	390C-Fibroblasts-Fibroblast-G\|390C / Donor, Lineage, Cell class and subclass (all cells)	COL6A3 TBX3 COMP ITGA8 FGFR4	2.45e-05	180	85	5	137fc14859c89e1ecd98bee388bb58c04b835847
ToppCell	390C-Fibroblasts-Fibroblast-G-\|390C / Donor, Lineage, Cell class and subclass (all cells)	COL6A3 TBX3 COMP ITGA8 FGFR4	2.45e-05	180	85	5	cd6790de050151fedfa2c5ea6ad58b72665414b2
ToppCell	facs-Liver-Hepatocytes-24m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACO1 C4B FGFR4 GPT2 KLB	2.66e-05	183	85	5	d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF21A SYNE2 PKHD1 BAIAP2 CAVIN2	2.73e-05	184	85	5	42ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCell	pdx-Tumor_cells-T0\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	GSE1 HECTD4 PKHD1 ATP4A KLB	2.80e-05	185	85	5	1d874608aa2062024323512f68889219471b2f00
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE2 SLC22A5 PKHD1 PPARA BAIAP2	2.95e-05	187	85	5	dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE2 SLC22A5 PKHD1 PPARA BAIAP2	2.95e-05	187	85	5	f1356273bd3587b6883295edf15cb9cdb706c057
ToppCell	droplet-Kidney-nan-3m-Endothelial-kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX3 RSAD2 LTBP1 F8 CAVIN2	2.95e-05	187	85	5	d72012e94857606f39975cf672f6b8c2e0fe093e
ToppCell	COPD-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	MTA2 KIF21A SYNE2 AKNA CAVIN2	3.02e-05	188	85	5	186fe1ea328c942910190a4240262c0d8642ea3b
ToppCell	droplet-Kidney-nan-3m-Endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX3 RSAD2 LTBP1 F8 CAVIN2	3.26e-05	191	85	5	dc58d45fafd224d2761aefbe0ce79f66b50c1c03
ToppCell	Calu_3-infected-SARSCoV2\|infected / Cell line, Condition and Strain	UBA7 RSAD2 NMI SYNE2 PARP12	3.26e-05	191	85	5	2da876d26f37a00dbdf1ee79d724306e8b20f304
ToppCell	ASK440-Mesenchymal\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	COL6A3 COMP ITGA8 LTBP1 FGFR4	3.26e-05	191	85	5	f12959eebb4167e1aa03de05d7711a702c58b3c9
ToppCell	ASK440-Mesenchymal-Fibroblast\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	COL6A3 COMP ITGA8 LTBP1 FGFR4	3.26e-05	191	85	5	387296b5377ef6839f0812e5b3529a10b5f7d530
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL6A3 SETBP1 ITGA8 LTBP1 FGFR4	3.34e-05	192	85	5	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	droplet-Bladder-BLADDER-1m-Endothelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FREM2 SCGB3A1 RSAD2 PLXND1 CAVIN2	3.42e-05	193	85	5	3a5090f81f35026f435f4a250d1e77601a53af15
ToppCell	droplet-Bladder-BLADDER-1m-Endothelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FREM2 SCGB3A1 RSAD2 PLXND1 CAVIN2	3.42e-05	193	85	5	13731b7fc1e3bec0cebc44bad7e2ecea358bb76a
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL6A3 SETBP1 ITGA8 LTBP1 FGFR4	3.42e-05	193	85	5	b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell	COVID-19-Fibroblasts-Other_FB\|COVID-19 / group, cell type (main and fine annotations)	COL6A3 COMP SETBP1 ITGA8 LTBP1	3.42e-05	193	85	5	e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell	human_hepatoblastoma-Tumor_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	TBX3 KIF21A ARFGEF2 DIDO1 GPT2	3.42e-05	193	85	5	503a979328c68b096680b71359a26f02fafdff35
ToppCell	ASK428-Mesenchymal\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	COL6A3 COMP ITGA8 LTBP1 FGFR4	3.60e-05	195	85	5	2b156163975d9a3d3fda1402acd9831d0fdc9e25
ToppCell	Bronchial_Biopsy-Mesenchymal-Fibroblasts\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	COL6A3 TBX3 COMP ITGA8 LTBP1	3.60e-05	195	85	5	5870b2956d50d6550a3174a220a6cc70c5538d70
ToppCell	ASK428-Mesenchymal-Fibroblast\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	COL6A3 COMP ITGA8 LTBP1 FGFR4	3.60e-05	195	85	5	c269c0d894a0f55da6495b59d4b9abb9f68df684
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D122\|Adult / Lineage, Cell type, age group and donor	COL6A3 SETBP1 ITGA8 LTBP1 FGFR4	3.60e-05	195	85	5	aa0add081881d349099d12efca5cdee098038d4e
ToppCell	Children_(3_yrs)-Mesenchymal\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL6A3 SETBP1 ITGA8 LTBP1 FGFR4	3.69e-05	196	85	5	bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 SETBP1 ITGA8 LTBP1 FGFR4	3.78e-05	197	85	5	94a9603cbd3516fbcce871909693b88f20d41713
ToppCell	IPF-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	COL6A3 COMP GSE1 ITGA8 LTBP1	3.78e-05	197	85	5	f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control_saline / Treatment groups by lineage, cell group, cell type	NBEAL2 KIF21A SYNE2 PKHD1 BAIAP2	3.87e-05	198	85	5	85f424cd9bb3117c9e322031024aabb87696ce47
ToppCell	Adult-Mesenchymal\|Adult / Lineage, Cell type, age group and donor	COL6A3 SETBP1 ITGA8 LTBP1 FGFR4	3.87e-05	198	85	5	26e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCell	Control_saline-Epithelial_alveolar-AT_1\|Control_saline / Treatment groups by lineage, cell group, cell type	NBEAL2 KIF21A SYNE2 PKHD1 BAIAP2	3.87e-05	198	85	5	9b161285df7a4e51618f3517cfc5b8221ba55786
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TBX3 SYNE2 ITGA8 F8 CAVIN2	3.96e-05	199	85	5	5d976d57872a8a25a11fe8cd53b01aa21a1a519a
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DCHS1 ITGA8 PLXND1 F8 CAVIN2	3.96e-05	199	85	5	8b62d43af8b2ebb4c1b2d068d50beaf35728dbe7
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	KIF21A SYNE2 PKHD1 BAIAP2 CAVIN2	3.96e-05	199	85	5	1c70e7d6bd25980e1b92aa1cac3f3c95d9651b4b
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	KIF21A SYNE2 PKHD1 BAIAP2 CAVIN2	3.96e-05	199	85	5	a270630626df614f8605abddb7dee7c4d74f6149
ToppCell	Kidney-Endothelial\|Kidney / Skin and Kidney Cells in Lupus Nephritis Patients.	RSAD2 DCHS1 PLXND1 F8 CAVIN2	3.96e-05	199	85	5	b543f0686522df43737e9ffa5c9733e42b8a9f4d
ToppCell	COVID-19-kidney-Glomerular_EC\|kidney / Disease (COVID-19 only), tissue and cell type	TBX3 ITGA8 PLXND1 F8 CAVIN2	3.96e-05	199	85	5	fffd2f9042b55531dac4e5b463b5cee80402e7bb
ToppCell	proximal-3-mesenchymal\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL6A3 TBX3 ITGA8 LTBP1 FGFR4	4.06e-05	200	85	5	94250991f78ea56810412d00a4bb645eb975478c
ToppCell	Biopsy_Other_PF-Mesenchymal-Myofibroblasts\|Biopsy_Other_PF / Sample group, Lineage and Cell type	COL6A3 COMP ITGA8 LTBP1 FGFR4	4.06e-05	200	85	5	e504570fd7eec1524c401b1cfa9d10822d80d994
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / Treatment groups by lineage, cell group, cell type	KIF21A SYNE2 PKHD1 BAIAP2 CAVIN2	4.06e-05	200	85	5	2dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCell	Tracheal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A3 COMP ITGA8 LTBP1 FGFR4	4.06e-05	200	85	5	8ab0051544ea32eb8b3f7f8ba7582deaf8bf26c0
ToppCell	proximal-mesenchymal\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL6A3 TBX3 ITGA8 LTBP1 FGFR4	4.06e-05	200	85	5	29f3a5c85404c6537d6405d599ebae281e0d4d4f
ToppCell	LPS_only-Epithelial_alveolar-AT_1\|LPS_only / Treatment groups by lineage, cell group, cell type	KIF21A SYNE2 PKHD1 BAIAP2 CAVIN2	4.06e-05	200	85	5	9a6ae40f3e17cd44ee5fd73260713b920aa2ea15
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A3 SETBP1 ITGA8 LTBP1 FGFR4	4.06e-05	200	85	5	311fab076f2ceb258e3970eb21e39344b894042a
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TBX3 DCHS1 PLXND1 F8 CAVIN2	4.06e-05	200	85	5	ced14d83222dbebca85c40540e76824e683354f3
ToppCell	Biopsy_IPF-Mesenchymal-Myofibroblasts\|Biopsy_IPF / Sample group, Lineage and Cell type	COL6A3 COMP ITGA8 LTBP1 FGFR4	4.06e-05	200	85	5	c2c6f687c49ba790174b27c7b8b084af30b34c86
ToppCell	droplet-Heart-nan-18m-Hematologic-erythrocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RSAD2 ADAT3 E2F2 NACAD	4.72e-05	104	85	4	060f0baca239ab89c18be40c1aa31931f4791b62
ToppCell	droplet-Lung-30m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l11\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CAPN9 RSAD2 PRDX2 NACAD	7.73e-05	118	85	4	a58dc4fcd92adcae5fae364052be4b909797e9f0
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C4A C4B PPARA F8	9.08e-05	123	85	4	a45d6907c041ad3f3218cd46dccfc25d4bd961cb
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZNF438 UBA7 PKHD1 IQCN	1.19e-04	132	85	4	a1fda8c5287168c4f159203ed27cadfb4ce1b131
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPN9 C4B CCL24 SIRT5	1.42e-04	138	85	4	c1a46fbf1beffa12c3d1b78361e0613e2e9e2d13
ToppCell	E16.5-samps-Epithelial-Alveolar_epithelial_precursor-Noncycling_AT1_Precursor\|E16.5-samps / Age Group, Lineage, Cell class and subclass	CAPN9 KLF5 TEX26 TMPRSS11F	2.15e-04	154	85	4	8a643d91896af9b630a715fb284c1523d01ad1a3
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_B0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	EXD3 HECTD4 E2F2 LTBP1	2.21e-04	155	85	4	a16e3a72badafa78a3efc4f4ab62396f0ce99d1e
ToppCell	FLU-Healthy-1\|Healthy / Virus stimulation, Condition and Cluster	RSAD2 SYNE2 IQCN F8	2.43e-04	159	85	4	97c8e16a7ac10ebba96daee97f9fb1d4a404f23b
ToppCell	FLU-Healthy-1\|FLU / Virus stimulation, Condition and Cluster	RSAD2 SYNE2 IQCN F8	2.43e-04	159	85	4	fe2a9f79b058e89214256e736f6e266830cdfa28
ToppCell	COVID-19-kidney-Epithelial_(EC)\|kidney / Disease (COVID-19 only), tissue and cell type	ITGA8 PLXND1 F8 CAVIN2	2.49e-04	160	85	4	0d4880f85565d8c540c94a8f8109147b3029279a
ToppCell	mild_COVID-19_(asymptomatic)-Neutrophil\|World / disease group, cell group and cell class (v2)	RSAD2 NMI KLF5	2.73e-04	66	85	3	e71738a3a84be93053d1ed20d030e4c606f8f402
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TTLL6 IQCN NACAD ATP4B	2.87e-04	166	85	4	d96c562e1483adb4cdd817b68133f03356d7279b
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	KIF21A SYNE2 AKNA F8	2.93e-04	167	85	4	abc4ba308ca3be41b0da604f5d82579fd58dff7b
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EPN3 SCGB3A1 LRRC24 SETBP1	3.00e-04	168	85	4	de0b00bc405c898d08a06b2e585fb62c0ab9a66e
ToppCell	facs-Marrow-B-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RSAD2 HECTD4 E2F2 PRDX2	3.00e-04	168	85	4	08fe8fa43c343c03f9a2f0b982192fde04a7c027
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)\|368C / Donor, Lineage, Cell class and subclass (all cells)	GRIN2B F8 ATP4B CAVIN2	3.00e-04	168	85	4	a74c8a9e3299183fba31ce3053ef325b5dbcd104
ToppCell	facs-Marrow-B-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RSAD2 HECTD4 E2F2 PRDX2	3.00e-04	168	85	4	d4053b2fffb19e0376b8ceb92e87ec4447d96a3e
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	GRIN2B F8 ATP4B CAVIN2	3.00e-04	168	85	4	dae37b316ce80dfe4236c4ed7f0d4e7c340fa7b6
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A3 C4A C4B F8	3.00e-04	168	85	4	d2b91f2adc95dcfa623f8d7ca2df1c6f884da988
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX3 SCGB3A1 ITGA8 F8	3.07e-04	169	85	4	87116c33c5ca8cb1862e103e5607b1df4d264569
ToppCell	5'-Adult-LargeIntestine-Epithelial-goblet-Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CAPN9 KLF5 ANO7 IQCN	3.21e-04	171	85	4	48125d825ca2d7ef34564250f5b47d2a579e03c9
ToppCell	droplet-Pancreas-Exocrine-18m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPN3 PKHD1 FGFR4 GPT2	3.21e-04	171	85	4	5447b78148f7bccb727e2fc108589b2af02a5d31
ToppCell	COVID-19_Mild-Neu_2\|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients	DPY19L4 SDR39U1 MRTFA CAPN10	3.28e-04	172	85	4	f5fd08b42c002d4693646b27e7b708eceb49524f
ToppCell	droplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cel\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPN3 PKHD1 FGFR4 GPT2	3.28e-04	172	85	4	a7eee0a30d2fe20c865a07b9004c6a821a72c0c4
ToppCell	droplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPN3 PKHD1 FGFR4 GPT2	3.28e-04	172	85	4	0a9fe2cd28203970295a1288078c66eadac1c9ed
ToppCell	droplet-Spleen-SPLEEN-30m-Hematologic-erythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RSAD2 HECTD4 E2F2 PRDX2	3.35e-04	173	85	4	a8fb8db6061fa4d8d56a7b45004ecbd344501573
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FREM2 SYNE2 C4B LTBP1	3.35e-04	173	85	4	30d67738633493d47f06ae452424382f069b6c0a
ToppCell	droplet-Liver-Npc-21m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C4A FGFR4 CAPN10	3.39e-04	71	85	3	cf4c8715c2bd77fc86e45cc01bcc7aa6044e091d
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FREM2 SYNE2 C4B LTBP1	3.43e-04	174	85	4	a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RSAD2 E2F2 PRDX2 NACAD	3.43e-04	174	85	4	81ab196e36cac2a7974d6e3fe457efffddfd03bb
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 TBX3 COMP LTBP1	3.50e-04	175	85	4	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	UBA7 RSAD2 NMI ACO1	3.50e-04	175	85	4	97616bb5c127284aa9e67bc336dfcf29e137164b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CAPN9 COL6A3 ITGA8 LTBP1	3.50e-04	175	85	4	795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|390C / Donor, Lineage, Cell class and subclass (all cells)	COL6A3 TBX3 COMP LTBP1	3.58e-04	176	85	4	852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	COL6A3 TBX3 COMP LTBP1	3.58e-04	176	85	4	d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCell	356C-Fibroblasts-Fibroblast-G\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL6A3 ITGA8 FGFR4 CAVIN2	3.66e-04	177	85	4	8220cc2fc0ee8764a67a3be51d75248be2453040
ToppCell	5'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WDR4 GPATCH1 SETBP1 PPP1R9B	3.66e-04	177	85	4	e1e45956887371b1c18f1eb479dd930031497520
ToppCell	facs-Brain_Myeloid-Striatum-24m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NBEAL2 E2F2 SDR39U1 MRTFA	3.66e-04	177	85	4	f6b9d91d46830d0d207b0abd4ee5a4942fd99774
ToppCell	356C-Fibroblasts-Fibroblast-G-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL6A3 ITGA8 FGFR4 CAVIN2	3.66e-04	177	85	4	7617270f49cd6b7ba66db72d20560cee985012b2
ToppCell	droplet-Marrow-nan-24m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RSAD2 HECTD4 E2F2 PRDX2	3.74e-04	178	85	4	b4e15c176875cd226854a0019495309d02730c42
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	COMP ARFGEF2 DIDO1 LTBP1	3.74e-04	178	85	4	edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCell	droplet-Spleen-nan-24m-Hematologic-erythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RSAD2 E2F2 PRDX2 NACAD	3.74e-04	178	85	4	9c4950357087212b2388116ba8866c359628694d
ToppCell	droplet-Bladder-BLADDER-1m-Endothelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FREM2 SCGB3A1 DPY19L4 LTBP1	3.74e-04	178	85	4	6bef4ef48f649c6e38ae732bc08e6d7814db588b
ToppCell	droplet-Marrow-nan-24m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RSAD2 HECTD4 E2F2 PRDX2	3.82e-04	179	85	4	7e6da098976c7801d31dcc0201f813d2bc8b07fc
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DCHS1 ITGA8 PLXND1 F8	3.82e-04	179	85	4	8f9e538c822940785130297712b75131812a4603
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE2 SLC22A5 PPARA BAIAP2	3.90e-04	180	85	4	f8bdfd7bf7b3d52c659a29d8f5f80858e79da83e
Disease	Heterotopia, Periventricular, Autosomal Recessive	DCHS1 ARFGEF2	2.40e-05	3	84	2	C1842563
Disease	stomach cancer (is_implicated_in)	CAPN9 GSE1 FGFR4 ATP4B	5.42e-05	72	84	4	DOID:10534 (is_implicated_in)
Disease	lean body mass	SLC22A5 ZNF638 DIDO1 LTBP1 FGFR4 BAIAP2 AP3D1	1.06e-04	379	84	7	EFO_0004995
Disease	systemic lupus erythematosus (implicated_via_orthology)	MTA2 C4A C4B	2.53e-04	43	84	3	DOID:9074 (implicated_via_orthology)
Disease	smoking behavior, BMI-adjusted waist circumference	ARFGEF2 LTBP1 IQCN FGFR4	4.16e-04	122	84	4	EFO_0004318, EFO_0007789
Disease	hyperhomocysteinemia (implicated_via_orthology)	GRIN2B F8	4.33e-04	11	84	2	DOID:9279 (implicated_via_orthology)
Disease	alcohol consumption measurement, alcohol drinking	HECTD4 KLB	5.19e-04	12	84	2	EFO_0004329, EFO_0007878
Disease	FEV/FEC ratio	ZNF438 FREM2 COL6A3 SYNE2 ZNF516 ITGA8 LTBP1 DLEC1 FGFR4 AP3D1 MRTFA	7.12e-04	1228	84	11	EFO_0004713
Disease	keratoconus	KLF5 PKHD1 GRIN2B	8.95e-04	66	84	3	MONDO_0015486
Disease	focal segmental glomerulosclerosis	GPATCH1 FGFR4	9.36e-04	16	84	2	EFO_0004236
Disease	serum gamma-glutamyl transferase measurement	GSE1 MAP1S KLF5 NBEAL2 GPATCH1 HECTD4 PKHD1 E2F2 KLB	1.17e-03	914	84	9	EFO_0004532
Disease	Myeloid Leukemia	SETBP1 PRDX2	1.19e-03	18	84	2	C0023470
Disease	Leukemia, Monocytic, Chronic	SETBP1 PRDX2	1.19e-03	18	84	2	C0023466
Disease	smoking behavior, BMI-adjusted waist-hip ratio	IQCN FGFR4 PLXND1	1.92e-03	86	84	3	EFO_0004318, EFO_0007788
Disease	carpal tunnel syndrome	ZNF438 LTBP1 MRTFA	2.12e-03	89	84	3	EFO_0004143
Disease	body surface area	PKHD1 DIDO1 LTBP1 DLEC1 FGFR4 PPARA BAIAP2	2.40e-03	643	84	7	EFO_0022196
Disease	cognitive function measurement	ZNF438 EXD3 GBF1 SETBP1 TEX26 PKHD1 ZNF638 LTBP1 GRIN2B BAIAP2 MRTFA	2.46e-03	1434	84	11	EFO_0008354
Disease	mean platelet volume	GSE1 SETBP1 SYNE2 SLC22A5 HTR3D LTBP1 PLXND1 CAVIN2 MRTFA	2.46e-03	1020	84	9	EFO_0004584
Disease	waist-hip ratio	GSE1 SETBP1 SYNE2 HECTD4 DLEC1 IQCN GRIN2B FGFR4 PLXND1 AP3D1	2.51e-03	1226	84	10	EFO_0004343

Protein segments in the cluster

Peptide	Gene	Start	Entry
VPFKPARVILQDFTG	ACO1	76	P21399
AFPRIFIPAKAVEAA	GPT2	441	Q8TD30
FAPAAAPQAVRAGAV	ADAT3	251	Q96EY9
ASPRARAVAVKGPVQ	CCL24	96	O00175
QVLVPAGSARPVAFS	C4B	886	P0C0L5
PFRAVAEPGIQLKAV	COMP	626	P49747
APQVAKTRNPFLTGL	EPN3	516	Q9H201
AFEPSRQAAVPLVKV	GSE1	611	Q14687
AVPAGNTVKFRCPAA	FGFR4	161	P22455
RLGTAAPPKANFIEA	ARFGEF2	51	Q9Y6D5
AVRKAVAIPVFANGN	DUS1L	196	Q6P1R4
IRAVAKNTTPGAALP	CAPN10	496	Q9HC96
IVKFLPSNGSAPRVD	ATP4B	186	P51164
PEVIPTAAARAGQRK	CBY3	206	A6NI87
VSALFAGELNPVAPK	AP3D1	596	O14617
APNPVVFVATKDTRA	MTA2	601	O94776
ANVKAPPQVAVAAGT	IQCN	526	Q9H0B3
AGSPAKPRIADFVLV	ANO7	101	Q6IWH7
VPPKPANTAAARAIF	DCHS1	3216	Q96JQ0
LAARSPVVSPFGVAQ	DCHS1	3261	Q96JQ0
ANKLFGAPEPSTIAR	LARP1	751	Q6PKG0
APNTGAPRFIKQVLS	nan	116	O00370
SRAAAPKATPVAAAK	MAP1S	871	Q66K74
VSRVPAQPAAFGRAL	FREM2	41	Q5SZK8
VAPPGVVVSRANKRS	EIF2B5	6	Q13144
EKARQLAAATAPIPG	GPATCH1	126	Q9BRR8
KATPVFRAPGLTSVA	PLXND1	461	Q9Y4D7
PAAAPFTKQGRQVVR	LTBP1	126	Q14766
FVINRSKPLFAEGPA	LRRC24	471	Q50LG9
EANRPGKVPFLRVAT	F8	1556	P00451
NQPLAARPIKGFAVV	HECTD4	3156	Q9Y4D8
ARIGKPAPDFKATAV	PRDX2	6	P32119
PDARTASVLVGAPKA	ITGA8	66	P53708
ETRVAGPPFKANTLI	MED14	1286	O60244
EFVRGNASFVRPPAK	PARP12	626	Q9H0J9
NGDPVAVAKAQPRTF	BRME1	576	Q0VDD7
RALASAAGQTPKVVP	E2F2	6	Q14209
AVRPPAAAAAKPVAT	COL6A3	2951	P12111
TFGPAIAAVQKVSPT	DDX12P	906	Q92771
IKRQAPVAAVFAGSP	DPY19L4	571	Q7Z388
SAALVGAVRKPVVPS	DIDO1	631	Q9BTC0
VAATPGKAEATRVLP	AKNA	801	Q7Z591
PAIVPAARKATAAVI	LYPLA1	11	O75608
GVKPPAALQATARAD	GBF1	1276	Q92538
PRLFPDGIVTVANAK	KLB	156	Q86Z14
PPFISEAAVRGNAAV	EMC6	11	Q9BV81
FIPLPSAVVQAVFGR	SDR39U1	241	Q9NRG7
IPASVFVKQPVSGAV	CAVIN2	166	O95810
KALARVIPQDQSFGP	CAPN9	111	O14815
QEPAKAAVAFRVSPN	DLEC1	1676	Q9Y238
AKANGIVVPSTIFDP	SLC22A5	301	O76082
RAAFKSGQDAVPVPK	ATP4A	441	P20648
QVLVPAGSARPVAFS	C4A	886	P0C0L4
RVILSGKASNNPPFV	PPARA	226	Q07869
RALPGKEAFAPLTVQ	TBX3	471	O15119
PAAFAGKLLSVFRQP	RSAD2	6	Q8WXG1
ATSVPAPRAKQFRAV	SYNE2	6791	Q8WXH0
GKAPQVRAASAPAKE	TCOF1	431	Q13428
PAVFRDLSKPIGVVN	NBEAL2	2116	Q6ZNJ1
GVNFTARSKPFAVLP	PKHD1	3836	P08F94
VVVAFPAARLSTGPA	MRTFA	406	Q969V6
AGRPTRFVKIAPAIQ	SUPT20HL2	551	P0C7V6
PAAFQAVFDRKAIGP	HTR3D	41	Q70Z44
RAFPAQTASGFKQRP	BAIAP2	476	Q9UQB8
QEAVAGRIPAIFSPA	TRAF2	366	Q12933
IARAGAQPSANSKPV	ZNF516	936	Q92618
ATFGATITPPAVKRN	TMPRSS11F	261	Q6ZWK6
AFARRPTVGAQIPEK	SSX2	6	Q16385
PKAEVAAAAARGLNP	UBA7	491	P41226
FPASKGIRAFPLQCI	KIF21A	1326	Q7Z4S6
PKETVALAFVRENPG	TTLL6	26	Q8N841
EAFFTILPQRKGAVP	TRMT10A	266	Q8TBZ6
VDPQAPQKFAASRIA	WDR4	236	P57081
AFTPKTGAVPALIRQ	TEX26	36	Q8N6G2
APQVAARGVPVAEFN	SIRT5	261	Q9NXA8
IPALEPVASFAKAQG	SETBP1	251	Q9Y6X0
FNAATKVASRLPVPQ	ZNF438	336	Q7Z4V0
FLVGSAKPVAQPVAA	SCGB3A1	21	Q96QR1
QADIPIRSPFGIVKA	ZNF638	376	Q14966
RVNFVAGAVEPHKAP	TCIRG1	166	Q13488
VSAVVGPAAEAKSPR	ZNF296	206	Q8WUU4
VFAQLKPVLGAANPA	KLF5	26	Q13887
GRKPVAAATIVPRQA	NACAD	576	O15069
AVSEGAAPQIPARAF	EXD3	616	Q8N9H8
PRAAGVPQVNSKLVS	PPP1R9B	231	Q96SB3
FRQPTVAGASKARPD	GRIN2B	1406	Q13224
TAKPVPLNSGVRFQV	NMI	136	Q13287