Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	intermediate filament cytoskeleton organization	KRT13 SYNM KRT34 KRT35 KRT39 KRT40 MACF1 KRT36	2.84e-07	99	135	8	GO:0045104
GeneOntologyBiologicalProcess	intermediate filament-based process	KRT13 SYNM KRT34 KRT35 KRT39 KRT40 MACF1 KRT36	3.07e-07	100	135	8	GO:0045103
GeneOntologyBiologicalProcess	regulation of hematopoietic progenitor cell differentiation	FLT1 ABL1 FNIP1 PRKDC NOTCH1 CDK6	5.31e-07	46	135	6	GO:1901532
GeneOntologyBiologicalProcess	intermediate filament organization	KRT13 KRT34 KRT35 KRT39 KRT40 KRT36	9.78e-06	75	135	6	GO:0045109
GeneOntologyBiologicalProcess	epithelial cell differentiation	KRT13 ABL1 KRT34 KRT35 ASCL5 WNT4 KRT39 AKAP9 PTPRS KRT40 SPRED1 MUC2 FZD2 HYDIN KRT36 NOTCH1 CDK6 SPINK5	1.52e-05	870	135	18	GO:0030855
GeneOntologyBiologicalProcess	regulation of anatomical structure morphogenesis	FLT1 ABL1 SYNE1 SPTA1 DBNL HLA-G RELA WNT4 HUWE1 WNK1 PTPRS AMOT MACF1 SPRED1 PRKDC FZD2 FMNL1 NOTCH1 SPINK5 BRWD1	2.80e-05	1090	135	20	GO:0022603
GeneOntologyBiologicalProcess	pro-B cell differentiation	FNIP1 PRKDC NOTCH1	7.47e-05	13	135	3	GO:0002328
GeneOntologyBiologicalProcess	epithelium development	FLT1 KRT13 ABL1 KRT34 KRT35 ASCL5 RELA WNT4 ASCL3 KRT39 AKAP9 PTPRS KRT40 NUP133 SPRED1 PRKDC MUC2 FZD2 HYDIN KRT36 NOTCH1 CDK6 SPINK5	7.88e-05	1469	135	23	GO:0060429
GeneOntologyBiologicalProcess	retrograde transport, endosome to Golgi	ASB14 TBC1D10A AP5Z1 CLTC DENND5A HEATR5B	8.20e-05	109	135	6	GO:0042147
GeneOntologyCellularComponent	ruffle	KIF18A ABL1 DBNL FRMD4B AMOT MACF1 ARHGEF4 CDK6	6.22e-05	206	136	8	GO:0001726
GeneOntologyCellularComponent	intermediate filament	KRT13 SYNM KRT34 KRT35 KRT39 KRT40 MACF1 KRT36	1.22e-04	227	136	8	GO:0005882
GeneOntologyCellularComponent	intermediate filament cytoskeleton	KRT13 SYNM KRT34 KRT35 KRT39 KRT40 MACF1 KRT36	3.32e-04	263	136	8	GO:0045111
Domain	Keratin_I	KRT13 KRT34 KRT35 KRT39 KRT40 KRT36	7.50e-07	44	136	6	IPR002957
Domain	IF	KRT13 SYNM KRT34 KRT35 KRT39 KRT40 KRT36	9.23e-07	72	136	7	PS00226
Domain	Filament	KRT13 SYNM KRT34 KRT35 KRT39 KRT40 KRT36	1.01e-06	73	136	7	PF00038
Domain	IF	KRT13 SYNM KRT34 KRT35 KRT39 KRT40 KRT36	1.34e-06	76	136	7	IPR001664
Domain	Intermediate_filament_CS	KRT13 SYNM KRT34 KRT35 KRT39 KRT36	6.45e-06	63	136	6	IPR018039
Domain	Clathrin	VPS11 CLTC VPS41	1.29e-05	7	136	3	PF00637
Domain	CHCR	VPS11 CLTC VPS41	1.29e-05	7	136	3	PS50236
Domain	Filament	KRT13 SYNM KRT35 KRT39 KRT40 KRT36	1.30e-05	71	136	6	SM01391
Domain	Clathrin_H-chain/VPS_repeat	VPS11 CLTC VPS41	2.06e-05	8	136	3	IPR000547
Domain	Sushi	PAMR1 CSMD3 SVEP1 NCAN C4BPB	3.75e-05	52	136	5	PF00084
Domain	CCP	PAMR1 CSMD3 SVEP1 NCAN C4BPB	4.52e-05	54	136	5	SM00032
Domain	FNIP_N_dom	FNIP2 FNIP1	5.26e-05	2	136	2	IPR028084
Domain	FNIP_mid_dom	FNIP2 FNIP1	5.26e-05	2	136	2	IPR028085
Domain	FNIP_C_dom	FNIP2 FNIP1	5.26e-05	2	136	2	IPR028086
Domain	FNIP_C	FNIP2 FNIP1	5.26e-05	2	136	2	PF14638
Domain	FNIP_M	FNIP2 FNIP1	5.26e-05	2	136	2	PF14637
Domain	FNIP_N	FNIP2 FNIP1	5.26e-05	2	136	2	PF14636
Domain	SLIDE	SMARCA5 SMARCA1	5.26e-05	2	136	2	IPR015195
Domain	ISWI_HAND-dom	SMARCA5 SMARCA1	5.26e-05	2	136	2	IPR015194
Domain	FNIP_fam	FNIP2 FNIP1	5.26e-05	2	136	2	IPR026156
Domain	EIF3C_N_dom	EIF3CL EIF3C	5.26e-05	2	136	2	IPR008905
Domain	eIF-3c_N	EIF3CL EIF3C	5.26e-05	2	136	2	PF05470
Domain	SLIDE	SMARCA5 SMARCA1	5.26e-05	2	136	2	PF09111
Domain	HAND	SMARCA5 SMARCA1	5.26e-05	2	136	2	PF09110
Domain	EIF3C	EIF3CL EIF3C	5.26e-05	2	136	2	IPR027516
Domain	ISWI	SMARCA5 SMARCA1	5.26e-05	2	136	2	IPR029915
Domain	SUSHI	PAMR1 CSMD3 SVEP1 NCAN C4BPB	5.39e-05	56	136	5	PS50923
Domain	Sushi_SCR_CCP_dom	PAMR1 CSMD3 SVEP1 NCAN C4BPB	5.88e-05	57	136	5	IPR000436
Domain	SNF2_N	TTF2 SMARCA5 ERCC6L2 SMARCA1	8.26e-05	32	136	4	IPR000330
Domain	SNF2_N	TTF2 SMARCA5 ERCC6L2 SMARCA1	8.26e-05	32	136	4	PF00176
Domain	DBINO	SMARCA5 SMARCA1	1.57e-04	3	136	2	IPR020838
Domain	DBINO	SMARCA5 SMARCA1	1.57e-04	3	136	2	PF13892
Domain	CLH	CLTC VPS41	1.57e-04	3	136	2	SM00299
Domain	DEAH_ATP_HELICASE	TTF2 SMARCA5 ERCC6L2 SMARCA1	1.64e-04	38	136	4	PS00690
Domain	PINT	EIF3CL COPS7A EIF3C	1.97e-04	16	136	3	SM00088
Domain	PCI_dom	EIF3CL COPS7A EIF3C	2.38e-04	17	136	3	IPR000717
Domain	PCI	EIF3CL COPS7A EIF3C	2.38e-04	17	136	3	PF01399
Domain	EGF_CA	PAMR1 SVEP1 EYS NCAN LTBP2 NOTCH1	2.70e-04	122	136	6	SM00179
Domain	EGF-like_Ca-bd_dom	PAMR1 SVEP1 EYS NCAN LTBP2 NOTCH1	2.95e-04	124	136	6	IPR001881
Domain	EGF	PAMR1 SVEP1 EYS NCAN LTBP2 NOTCH1	3.22e-04	126	136	6	PF00008
Domain	Spectrin	SYNE1 SPTA1 MACF1	6.01e-04	23	136	3	PF00435
Domain	EGF_Ca-bd_CS	SVEP1 EYS NCAN LTBP2 NOTCH1	7.17e-04	97	136	5	IPR018097
Domain	EGF_CA	SVEP1 EYS NCAN LTBP2 NOTCH1	7.86e-04	99	136	5	PS01187
Domain	ASX_HYDROXYL	SVEP1 EYS NCAN LTBP2 NOTCH1	8.23e-04	100	136	5	PS00010
Domain	ARM-type_fold	VPS11 HUWE1 WDFY4 CLTC PUM3 PRKDC STKLD1 HEATR5B FMNL1	8.55e-04	339	136	9	IPR016024
Domain	EGF-type_Asp/Asn_hydroxyl_site	SVEP1 EYS NCAN LTBP2 NOTCH1	1.07e-03	106	136	5	IPR000152
Domain	hEGF	SVEP1 EYS NOTCH1	1.08e-03	28	136	3	PF12661
Domain	Spectrin_repeat	SYNE1 SPTA1 MACF1	1.20e-03	29	136	3	IPR002017
Domain	SPEC	SYNE1 SPTA1 MACF1	1.60e-03	32	136	3	SM00150
Domain	Spectrin/alpha-actinin	SYNE1 SPTA1 MACF1	1.60e-03	32	136	3	IPR018159
Domain	DNA/RNA_helicase_DEAH_CS	TTF2 SMARCA5 ERCC6L2	2.08e-03	35	136	3	IPR002464
Pathway	REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE	KRT13 KRT34 KRT35 KRT39 KRT40 KRT36 SPINK5	3.50e-06	87	104	7	MM15351
Pathway	REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE	KRT13 KRT34 KRT35 KRT39 KRT40 KRT36 SPINK5	4.64e-05	129	104	7	M27649
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	COL5A2 KRT13 ABL1 KRT34 KRT35 SPTA1 ARHGEF12 DPYSL4 KRT39 KRT40 CLTC KRT36 SPINK5	8.03e-05	502	104	13	MM14537
Pathway	REACTOME_KERATINIZATION	KRT13 KRT34 KRT35 KRT39 KRT40 KRT36 SPINK5	1.36e-04	153	104	7	MM15343
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FNIP2 SYNE1 SPEG ARHGEF12 ZDHHC17 CSMD3 RSBN1 AKAP9 SV2A CLTC FNIP1 MACF1 ARHGEF4	1.10e-08	407	139	13	12693553
Pubmed	New consensus nomenclature for mammalian keratins.	KRT13 KRT34 KRT35 KRT39 KRT40 KRT36	2.06e-07	63	139	6	16831889
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	GPD2 SYNE1 SPTA1 DBNL ARHGEF12 DPYSL4 GRM1 EIF3CL UBA1 PTPRS SV2A AMOT NCAN CLTC MACF1 PLCL1 EIF3C ARHGEF4 USP54 PCM1 CKMT1A	2.68e-07	1431	139	21	37142655
Pubmed	Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.	SYNE1 MCM9 MACF1 HEATR5B	1.13e-06	20	139	4	21689717
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	NACC1 SYNE1 KSR2 ARHGEF12 DPYSL4 HUWE1 GRM1 UBA1 AKAP9 PLPP3 PTPRS NCAN CLTC MACF1 PLCL1 PCM1	1.66e-06	963	139	16	28671696
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	TOR1AIP2 DBNL HUWE1 ZDHHC17 WNK1 WDFY4 COPS7A ZNF32 WDHD1 COQ8A AMOT TET1 CLTC MACF1 SPRED1 CDK6 BRWD1	1.68e-06	1084	139	17	11544199
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	TTF2 NACC1 WNK1 AKAP9 AMOT PRKDC USP54 FMNL1 NOTCH1 PCM1 ALG13	1.96e-06	446	139	11	24255178
Pubmed	Global landscape of HIV-human protein complexes.	TOR1AIP2 GEMIN2 ARHGEF12 RNF213 HUWE1 UBA1 AKAP9 FNIP1 EIF3C PRKDC CKMT1A	2.47e-06	457	139	11	22190034
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TOR1AIP2 SMARCA5 LZTR1 NACC1 RNF213 GJD4 RSBN1 COQ8A SV2A SMARCA1 MACF1 VAX2 USP54 ANKS3 PCM1 ALG13 BRWD1	2.49e-06	1116	139	17	31753913
Pubmed	Characterization of a 190-kilobase pair domain of human type I hair keratin genes.	KRT34 KRT35 KRT36	5.16e-06	9	139	3	9756910
Pubmed	Human hair keratins.	KRT34 KRT35 KRT36	5.16e-06	9	139	3	7686952
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	SYNE1 WNK1 AKAP9 AMOT CLTC NUP133 MACF1 SPRED1 PUM3 EIF3C ZSCAN23	5.49e-06	497	139	11	23414517
Pubmed	The catalog of human hair keratins. I. Expression of the nine type I members in the hair follicle.	KRT34 KRT35 KRT36	7.34e-06	10	139	3	10391933
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	COL5A2 ABL1 HUWE1 EYS AP5Z1 CLTC MACF1 PRKDC PCM1	8.16e-06	332	139	9	37433992
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	SYNE1 SPTA1 ARHGEF12 RNF213 ZNF616 EIF3C ZNHIT2	1.09e-05	187	139	7	26460568
Pubmed	Charting the molecular network of the drug target Bcr-Abl.	KRT13 ABL1 KRT34 KRT35 SPTA1 CLTC PRKDC KRT36	1.25e-05	266	139	8	19380743
Pubmed	Clathrin-dependent mechanisms modulate the subcellular distribution of class C Vps/HOPS tether subunits in polarized and nonpolarized cells.	VPS11 CLTC VPS41	1.34e-05	12	139	3	21411634
Pubmed	Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.	RNF213 HUWE1 AKAP9 MACF1 PRKDC	1.40e-05	76	139	5	27542412
Pubmed	[Association of Inorganics Accumulation with the Activation of NF-κB Signaling Pathway and the iNOS Expression of Lung Tissue in Xuanwei Lung Cancer Patients].	RELA NOS2	1.59e-05	2	139	2	26805735
Pubmed	Daedalea gibbosa substances inhibit LPS-induced expression of iNOS by suppression of NF-kappaB and MAPK activities in RAW 264.7 macrophage cells.	RELA NOS2	1.59e-05	2	139	2	20127048
Pubmed	Expression of inducible nitric oxide synthase in the liver is under the control of nuclear factor kappa B in concanavalin A-induced hepatitis.	RELA NOS2	1.59e-05	2	139	2	17683476
Pubmed	Advanced glycosylation end products induce NF-kappaB dependent iNOS expression in RAW 264.7 cells.	RELA NOS2	1.59e-05	2	139	2	12242023
Pubmed	NOS2 regulation of NF-kappaB by S-nitrosylation of p65.	RELA NOS2	1.59e-05	2	139	2	17720813
Pubmed	EIF3C Promotes Lung Cancer Tumorigenesis by Regulating the APP/HSPA1A/LMNB1 Axis.	EIF3CL EIF3C	1.59e-05	2	139	2	36157221
Pubmed	Enzymatic Hydroxylation and Excision of Extended 5-Methylcytosine Analogues.	NEIL1 TET1	1.59e-05	2	139	2	33065111
Pubmed	Course of Brugia malayi infection in C57BL/6J NOS2 +/+ and -/- mice.	PRKDC NOS2	1.59e-05	2	139	2	11426950
Pubmed	Differential Expression of VEGFA Isoforms Regulates Metastasis and Response to Anti-VEGFA Therapy in Sarcoma.	FLT1 PRKDC	1.59e-05	2	139	2	28377452
Pubmed	Ligustilide prevents LPS-induced iNOS expression in RAW 264.7 macrophages by preventing ROS production and down-regulating the MAPK, NF-κB and AP-1 signaling pathways.	RELA NOS2	1.59e-05	2	139	2	21457761
Pubmed	Synergistic association of Notch and NFκB signaling and role of Notch signaling in modulating epithelial to mesenchymal transition in colorectal adenocarcinoma.	RELA NOTCH1	1.59e-05	2	139	2	25257945
Pubmed	Progression of pulmonary tuberculosis and efficiency of bacillus Calmette-Guérin vaccination are genetically controlled via a common sst1-mediated mechanism of innate immunity.	PRKDC NOS2	1.59e-05	2	139	2	17982083
Pubmed	Single-cell sequencing reveals SATB2/NOTCH1 signaling promotes the progression of malignancy of epithelial cells from papillary thyroid cancer.	SATB2 NOTCH1	1.59e-05	2	139	2	37877736
Pubmed	Notch1 expression, which is related to p65 Status, is an independent predictor of prognosis in colorectal cancer.	RELA NOTCH1	1.59e-05	2	139	2	21771876
Pubmed	Inducible nitric oxide synthase up-regulates Notch-1 in mouse cholangiocytes: implications for carcinogenesis.	NOS2 NOTCH1	1.59e-05	2	139	2	15887117
Pubmed	Novel type I hair keratins K39 and K40 are the last to be expressed in differentiation of the hair: completion of the human hair keratin catalog.	KRT39 KRT40	1.59e-05	2	139	2	17301834
Pubmed	Suppression of NF-κB by dieckol extracted from Ecklonia cava negatively regulates LPS induction of inducible nitric oxide synthase gene.	RELA NOS2	1.59e-05	2	139	2	24744158
Pubmed	Effects of Celastrol on growth inhibition of U937 leukemia cells through the regulation of the Notch1/NF-kappaB signaling pathway in vitro.	RELA NOTCH1	1.59e-05	2	139	2	20346213
Pubmed	PTPsigma is a receptor for chondroitin sulfate proteoglycan, an inhibitor of neural regeneration.	PTPRS NCAN	1.59e-05	2	139	2	19833921
Pubmed	Cloning of a DNA binding protein that is a tyrosine kinase substrate and recognizes an upstream initiator-like sequence in the promoter of the preprodynorphin gene.	ABL1 HUWE1	1.59e-05	2	139	2	7968380
Pubmed	ABL1, Overexpressed in Hepatocellular Carcinomas, Regulates Expression of NOTCH1 and Promotes Development of Liver Tumors in Mice.	ABL1 NOTCH1	1.59e-05	2	139	2	32171747
Pubmed	BCR/ABL downregulates DNA-PK(CS)-dependent and upregulates backup non-homologous end joining in leukemic cells.	ABL1 PRKDC	1.59e-05	2	139	2	19697154
Pubmed	Role of HLA-G in innate immunity through direct activation of NF-kappaB in natural killer cells.	HLA-G RELA	1.59e-05	2	139	2	17675239
Pubmed	Protein nitration promotes inducible nitric oxide synthase transcription mediated by NF-κB in high glucose-stimulated human lens epithelial cells.	RELA NOS2	1.59e-05	2	139	2	23454417
Pubmed	L-fucose reduces gut inflammation due to T-regulatory response in Muc2 null mice.	PRKDC MUC2	1.59e-05	2	139	2	36584066
Pubmed	Endocytosis-independent function of clathrin heavy chain in the control of basal NF-κB activation.	RELA CLTC	1.59e-05	2	139	2	21364927
Pubmed	Functional interaction between DNA-PK and c-Abl in response to DNA damage.	ABL1 PRKDC	1.59e-05	2	139	2	9109492
Pubmed	Ferrous citrate up-regulates the NOS2 through nuclear translocation of NFκB induced by free radicals generation in mouse cerebral endothelial cells.	RELA NOS2	1.59e-05	2	139	2	23029446
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	GPD2 SMARCA5 GEMIN2 SYNE1 HUWE1 UBA1 AMOT CLTC NUP133 MACF1 PUM3 EIF3C PRKDC HEATR5B PCM1	1.60e-05	1024	139	15	24711643
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	GPD2 SMARCA5 SYNE1 DBNL HUWE1 GRM1 TRIM14 EIF3CL UBA1 PDE12 AMOT CLTC SMARCA1 NUP133 PUM3 EIF3C PRKDC CKMT1A	1.61e-05	1425	139	18	30948266
Pubmed	A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.	KSR2 DYNC2I1 OSBP KLHL9 AMOT MCM9 FBXL2 ZNHIT2 CDK6	1.66e-05	363	139	9	25036637
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	GPD2 TOR1AIP2 KIF18A LZTR1 RNF213 RELA HUWE1 CNNM4 UBA1 AKAP9 PTPRS CLTC NUP133 EIF3C NOTCH1	2.11e-05	1049	139	15	27880917
Pubmed	A human MAP kinase interactome.	KRT13 SYNE1 NCKAP5 RELA ZDHHC17 WNK1 CLTC MACF1 PRKDC ARHGEF4	2.77e-05	486	139	10	20936779
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	TTF2 SMARCA5 HUWE1 PDE12 WDHD1 CLTC SMARCA1 NUP133 PUM3 EIF3C PRKDC CDK6	2.77e-05	704	139	12	29955894
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	NEIL1 KSR2 DYNC2I1 RNF213 WNT4 HUWE1 H6PD DNAH1 CNNM4 KLHL9 COQ8A PTPRS VPS41 FNIP1 MACF1 ARHGEF4 DENND5A PCM1	2.87e-05	1489	139	18	28611215
Pubmed	Unpackaging the genetics of mammalian fertility: strategies to identify the "reproductive genome".	DNAH1 AKAP9 BRWD1	3.37e-05	16	139	3	29878059
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	SMARCA5 DBNL HUWE1 WNK1 EIF3CL UBA1 NUP133 EIF3C ANKS3 PCM1	3.70e-05	503	139	10	16964243
Pubmed	Thrombin induces inducible nitric oxide synthase expression via the MAPK, MSK1, and NF-κB signaling pathways in alveolar macrophages.	RELA NOS2	4.75e-05	3	139	2	22004609
Pubmed	Oocyte-specific inactivation of Omcg1 leads to DNA damage and c-Abl/TAp63-dependent oocyte death associated with dramatic remodeling of ovarian somatic cells.	ABL1 ZNF830	4.75e-05	3	139	2	25168238
Pubmed	Contributions of the RhoGEF activity of p210 BCR/ABL to disease progression.	ABL1 ARHGEF12	4.75e-05	3	139	2	23207522
Pubmed	Caveolin-1 mediates chemoresistance in cisplatin-resistant ovarian cancer cells by targeting apoptosis through the Notch-1/Akt/NF-κB pathway.	RELA NOTCH1	4.75e-05	3	139	2	26503358
Pubmed	Heterologous down-regulation of angiotensin type 1 receptors by purinergic P2Y2 receptor stimulation through S-nitrosylation of NF-kappaB.	RELA NOS2	4.75e-05	3	139	2	21464294
Pubmed	c-Abl Tyrosine Kinase Is Regulated Downstream of the Cytoskeletal Protein Synemin in Head and Neck Squamous Cell Carcinoma Radioresistance and DNA Repair.	ABL1 SYNM	4.75e-05	3	139	2	33019757
Pubmed	T cell leukemia-associated human Notch/translocation-associated Notch homologue has I kappa B-like activity and physically interacts with nuclear factor-kappa B proteins in T cells.	RELA NOTCH1	4.75e-05	3	139	2	8642313
Pubmed	Casein kinase II-mediated phosphorylation of NF-kappaB p65 subunit enhances inducible nitric-oxide synthase gene transcription in vivo.	RELA NOS2	4.75e-05	3	139	2	15033982
Pubmed	Sphingolipid degradation by Leishmania major is required for its resistance to acidic pH in the mammalian host.	PRKDC NOS2	4.75e-05	3	139	2	21576322
Pubmed	Attenuated nephritis in inducible nitric oxide synthase knockout C57BL/6 mice and pulmonary hemorrhage in CB17 SCID and recombination activating gene 1 knockout C57BL/6 mice infected with Leptospira interrogans.	PRKDC NOS2	4.75e-05	3	139	2	21576342
Pubmed	Mercury inhibits nitric oxide production but activates proinflammatory cytokine expression in murine macrophage: differential modulation of NF-kappaB and p38 MAPK signaling pathways.	RELA NOS2	4.75e-05	3	139	2	12175822
Pubmed	Angiogenesis-related protein expression in bevacizumab-treated metastatic colorectal cancer: NOTCH1 detrimental to overall survival.	FLT1 NOTCH1	4.75e-05	3	139	2	26394830
Pubmed	Production of proinflammatory mediators in activated microglia is synergistically regulated by Notch-1, glycogen synthase kinase (GSK-3β) and NF-κB/p65 signalling.	RELA NOTCH1	4.75e-05	3	139	2	29049420
Pubmed	Binding kinetics of human ISWI chromatin-remodelers to DNA repair sites elucidate their target location mechanism.	SMARCA5 SMARCA1	4.75e-05	3	139	2	21738833
Pubmed	Cloning and characterization of the murine Imitation Switch (ISWI) genes: differential expression patterns suggest distinct developmental roles for Snf2h and Snf2l.	SMARCA5 SMARCA1	4.75e-05	3	139	2	11359880
Pubmed	Nitric oxide is involved in Mycobacterium bovis bacillus Calmette-Guérin-activated Jagged1 and Notch1 signaling.	NOS2 NOTCH1	4.75e-05	3	139	2	20147635
Pubmed	Serine 62 is a phosphorylation site in folliculin, the Birt-Hogg-Dubé gene product.	FNIP2 FNIP1	4.75e-05	3	139	2	19914239
Pubmed	Andrographolide exerts anti-inflammatory effects in Mycobacterium tuberculosis-infected macrophages by regulating the Notch1/Akt/NF-κB axis.	RELA NOTCH1	4.75e-05	3	139	2	32991757
Pubmed	Ultrasound stimulates NF-kappaB activation and iNOS expression via the Ras/Raf/MEK/ERK signaling pathway in cultured preosteoblasts.	RELA NOS2	4.75e-05	3	139	2	19288477
Pubmed	Catalytic domain of deubiquitinylase USP48 directs interaction with Rel homology domain of nuclear factor kappaB transcription factor RelA.	RELA USP48	4.75e-05	3	139	2	30628021
Pubmed	SNX4 in complex with clathrin and dynein: implications for endosome movement.	DNAH1 CLTC	4.75e-05	3	139	2	19529763
Pubmed	Hypoimmunogenic human iPSCs expressing HLA-G, PD-L1, and PD-L2 evade innate and adaptive immunity.	HLA-G PDCD1LG2	4.75e-05	3	139	2	38956724
Pubmed	HUWE1-dependent DNA-PKcs neddylation modulates its autophosphorylation in DNA damage response.	HUWE1 PRKDC	4.75e-05	3	139	2	32457294
Pubmed	Loss of FLCN-FNIP1/2 induces a non-canonical interferon response in human renal tubular epithelial cells.	FNIP2 FNIP1	4.75e-05	3	139	2	33459596
Pubmed	The NF-kappaB RelA subunit confers resistance to Leishmania major by inducing nitric oxide synthase 2 and Fas expression but not Th1 differentiation.	RELA NOS2	4.75e-05	3	139	2	19342670
Pubmed	Nuclear interaction between ADR-induced p65 and p53 mediates cardiac injury in iNOS (-/-) mice.	RELA NOS2	4.75e-05	3	139	2	24586632
Pubmed	Nuclear RPSA senses viral nucleic acids to promote the innate inflammatory response.	SMARCA5 RELA	4.75e-05	3	139	2	38114488
Pubmed	Expressions of nuclear factor kappaB, inducible nitric oxide synthase, and vascular endothelial growth factor in adenoid cystic carcinoma of salivary glands: correlations with the angiogenesis and clinical outcome.	RELA NOS2	4.75e-05	3	139	2	16243805
Pubmed	Assessment of community efforts to advance network-based prediction of protein-protein interactions.	KRT13 GEMIN2 KRT34 KRT35 KSR2 RABAC1 TRIM14 KRT39 KRT40 ZSCAN23 KRT36	4.87e-05	630	139	11	36949045
Pubmed	Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells.	FLT1 WNT4 FZD2	5.78e-05	19	139	3	21623369
Pubmed	Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.	SYNE1 SVEP1 CNNM4	5.78e-05	19	139	3	18711365
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	SMARCA5 LZTR1 SYNE1 RNF213 HUWE1 SMARCA1 NUP133 PUM3	6.04e-05	332	139	8	25693804
Pubmed	LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.	SYNE1 SPTA1 PKD1L2 IGSF10 KRT39 UBA1	6.14e-05	168	139	6	30631154
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	DBNL RELA HUWE1 WNK1 EIF3CL COPS7A OSBP UBA1 EHBP1L1 PDE12 WDHD1 NUP133 MACF1 EIF3C PRKDC USP48 SNRPF	7.40e-05	1455	139	17	22863883
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	TTF2 SMARCA5 DBNL HUWE1 UBA1 AMOT TET1 CLTC PRKDC PCM1	7.66e-05	549	139	10	38280479
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	HUWE1 WNK1 EIF3CL UBA1 PDE12 CLTC EIF3C PRKDC	7.73e-05	344	139	8	30333137
Pubmed	Snf2h Drives Chromatin Remodeling to Prime Upper Layer Cortical Neuron Development.	SATB2 SMARCA5 SMARCA1	7.88e-05	21	139	3	31680852
Pubmed	Putative complement control protein CSMD3 dysfunction impairs synaptogenesis and induces neurodevelopmental disorders.	SATB2 GRM1 CSMD3	9.10e-05	22	139	3	35245678
Pubmed	Simultaneous Detection of NF1, SPRED1, LZTR1, and NF2 Gene Mutations by Targeted NGS in an Italian Cohort of Suspected NF1 Patients.	LZTR1 SPRED1	9.47e-05	4	139	2	32575496
Pubmed	CARMA1 is a novel regulator of T-ALL disease and leukemic cell migration to the CNS.	PRKDC NOTCH1	9.47e-05	4	139	2	27698445
Pubmed	Short-Term In Vitro ROS Detection and Oxidative Stress Regulators in Epiretinal Membranes and Vitreous from Idiopathic Vitreoretinal Diseases.	RELA NOS2	9.47e-05	4	139	2	36567907
Pubmed	E3 ligase c-Cbl regulates intestinal inflammation through suppressing fungi-induced noncanonical NF-κB activation.	ABL1 RELA	9.47e-05	4	139	2	33962939
Pubmed	Human ubiquitin specific protease 31 is a deubiquitinating enzyme implicated in activation of nuclear factor-kappaB.	RELA USP48	9.47e-05	4	139	2	16214042
Pubmed	p21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation.	WNT4 NOTCH1	9.47e-05	4	139	2	15964998
Pubmed	Quantitative genome-wide methylation analysis of high-grade non-muscle invasive bladder cancer.	VAX2 ARHGEF4	9.47e-05	4	139	2	26929985
Interaction	KRT81 interactions	KRT13 KRT34 KRT35 KRT39 KRT40 NOS2 KRT36 PCM1	2.69e-09	53	138	8	int:KRT81
Interaction	KRT74 interactions	KRT13 KRT34 KRT35 KRT39 KRT40 KRT36	1.80e-07	37	138	6	int:KRT74
Interaction	C1orf216 interactions	KRT13 KRT34 ZDHHC17 KRT39 AMOT KRT40 KRT36	6.77e-07	73	138	7	int:C1orf216
Interaction	KRT85 interactions	KRT13 KRT34 KRT35 KRT39 KRT40 KRT36	3.77e-06	61	138	6	int:KRT85
Interaction	KRT83 interactions	KRT34 KRT35 KRT39 KRT40 KRT36 PCM1	7.14e-06	68	138	6	int:KRT83
Interaction	KRT71 interactions	KRT13 KRT34 KRT35 KRT40 KRT36	1.09e-05	43	138	5	int:KRT71
Interaction	KRT86 interactions	KRT34 KRT35 KRT39 KRT40 KRT36 PCM1	1.26e-05	75	138	6	int:KRT86
Interaction	PRPF18 interactions	NACC1 KRT34 KRT35 KRT39 KRT40 SPRED1 FMNL1	1.89e-05	120	138	7	int:PRPF18
Interaction	KRT78 interactions	KRT13 KRT34 KRT35 KRT39 KRT40 KRT36	2.96e-05	87	138	6	int:KRT78
Interaction	KRT3 interactions	KRT13 KRT34 KRT35 KRT39 KRT40 KRT36	3.16e-05	88	138	6	int:KRT3
Interaction	KRT2 interactions	KRT13 KRT34 KRT35 KRT39 KRT40 USP54 ZNHIT2 KRT36 PCM1	3.68e-05	236	138	9	int:KRT2
Interaction	EEF1AKMT3 interactions	TTF2 ARHGEF12 RELA HUWE1 WNK1 UBA1 EHBP1L1 WDHD1 VPS41 USP48 CDK6	4.27e-05	364	138	11	int:EEF1AKMT3
Interaction	KRT72 interactions	KRT13 KRT34 KRT35 KRT40 KRT36	5.21e-05	59	138	5	int:KRT72
Interaction	KRT79 interactions	KRT13 KRT34 KRT35 KRT40 KRT36	5.21e-05	59	138	5	int:KRT79
Interaction	GAN interactions	SYNE1 SPTA1 ARHGEF12 RNF213 RELA UBA1 ZNF616 EIF3C ZNHIT2	6.30e-05	253	138	9	int:GAN
Interaction	KRT4 interactions	KRT13 KRT34 KRT35 KRT40 KRT36	6.62e-05	62	138	5	int:KRT4
Interaction	BEX2 interactions	KRT34 ZDHHC17 KRT39 AKAP9 KRT40 SPRED1	9.00e-05	106	138	6	int:BEX2
Interaction	KRT82 interactions	KRT34 KRT35 KRT40 KRT36	1.17e-04	37	138	4	int:KRT82
Interaction	GPS1 interactions	SMARCA5 SYNE1 RELA HUWE1 COPS7A KLHL9 USP48 NOTCH1	1.31e-04	218	138	8	int:GPS1
Interaction	SHC3 interactions	KRT34 KRT35 KRT39 KRT40 USP54	1.36e-04	72	138	5	int:SHC3
Cytoband	17q21.2	KRT34 KRT35 KRT39 KRT40	6.32e-05	70	139	4	17q21.2
Cytoband	Ensembl 112 genes in cytogenetic band chr17q21	KRT13 KRT34 KRT35 KRT39 KRT40 FZD2 FMNL1 KRT36	1.04e-04	473	139	8	chr17q21
Cytoband	7q21-q22	AKAP9 CDK6	4.03e-04	10	139	2	7q21-q22
Cytoband	9p24.2	PUM3 PDCD1LG2	4.92e-04	11	139	2	9p24.2
GeneFamily	Keratins, type I	KRT13 KRT34 KRT35 KRT39 KRT40 KRT36	8.40e-09	28	100	6	608
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	PAMR1 CSMD3 SVEP1 NCAN C4BPB	1.56e-05	57	100	5	1179
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	KIF18A GRM1 WNK1 AKAP9 SPRED1 PLCL1 HYDIN	6.56e-05	181	100	7	694
GeneFamily	Guanylate cyclase receptors\|DENN/MADD domain containing	FNIP2 FNIP1 DENND5A	3.46e-04	25	100	3	504
GeneFamily	Endogenous ligands\|Minor histocompatibility antigens	WNK1 NUP133 PUM3	2.82e-03	51	100	3	870
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#3	SATB2 SMARCA5 SYNE1 DYNC2I1 RNF213 WNK1 TBC1D10A TET1 MACF1 HEATR5B FMNL1 PCM1 BRWD1	3.34e-06	432	133	13	Facebase_RNAseq_e10.5_Maxillary Arch_1000_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_500_k-means-cluster#3	SATB2 SMARCA5 SYNE1 DYNC2I1 RNF213 TBC1D10A TET1 FMNL1 CKMT1A	3.36e-05	255	133	9	Facebase_RNAseq_e10.5_Maxillary Arch_500_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000	SATB2 SMARCA5 KRT13 SYNE1 ARHGEF12 DYNC2I1 RNF213 WNK1 AKAP9 TBC1D10A TET1 MACF1 VAX2 HEATR5B FMNL1 PCM1 CKMT1A BRWD1	4.59e-05	989	133	18	Facebase_RNAseq_e10.5_Maxillary Arch_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_500	SATB2 SMARCA5 KRT13 SYNE1 DYNC2I1 RNF213 AKAP9 TBC1D10A TET1 VAX2 FMNL1 CKMT1A	6.36e-05	492	133	12	Facebase_RNAseq_e10.5_Maxillary Arch_500
ToppCell	343B-Fibroblasts-Fibroblast-G\|343B / Donor, Lineage, Cell class and subclass (all cells)	COL5A2 ABCA9 SVEP1 PHEX IGSF10 PLPP3 PTPRS MACF1 LTBP2	1.35e-08	199	139	9	f4b6c095cbe7a38b310adc49be4069e4d56e6a66
ToppCell	343B-Fibroblasts-Fibroblast-G-\|343B / Donor, Lineage, Cell class and subclass (all cells)	COL5A2 ABCA9 SVEP1 PHEX IGSF10 PLPP3 PTPRS MACF1 LTBP2	1.35e-08	199	139	9	9c6d1c328bfbb6547f4c7bb2a784576a56bd72af
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TRHDE COL5A2 SYNE1 SVEP1 PHEX IGSF10 AKAP9 PLPP3 MACF1	1.41e-08	200	139	9	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	TTF2 RNF213 HUWE1 MCM9 CLTC MACF1 PRKDC CDK6	1.25e-07	185	139	8	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	TTF2 RNF213 HUWE1 MCM9 CLTC MACF1 PRKDC CDK6	1.30e-07	186	139	8	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	facs-GAT-Fat-3m\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT13 HUWE1 WNK1 ABCA9 IGSF10 UBA1 PTPRS CLTC	1.53e-07	190	139	8	1d92be1b41cff59e834a9d28868f554bd1f3e471
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TRHDE SPEG SVEP1 PHEX IGSF10 PLPP3 PTPRS PLCL1	1.60e-07	191	139	8	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A2 ABCA9 SVEP1 IGSF10 PLPP3 PTPRS MACF1 LTBP2	1.87e-07	195	139	8	df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A2 ABCA9 SVEP1 IGSF10 PLPP3 PTPRS MACF1 LTBP2	1.87e-07	195	139	8	4243190ad291d56694e2155954dbaa879c9d3844
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A2 ABCA9 SVEP1 IGSF10 PLPP3 PTPRS MACF1 LTBP2	1.94e-07	196	139	8	9737a5f006d37b549f281e1863aca558e1e4dc99
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A2 ABCA9 SVEP1 IGSF10 PLPP3 PTPRS MACF1 LTBP2	1.94e-07	196	139	8	42e9828222a9663525d571633e8a454c30bfa7f8
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A2 ABCA9 SVEP1 IGSF10 PLPP3 PTPRS MACF1 LTBP2	1.94e-07	196	139	8	cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TRHDE COL5A2 SYNE1 DYNC2I1 SVEP1 PHEX IGSF10 MACF1	2.02e-07	197	139	8	fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A2 ABCA9 SVEP1 IGSF10 PLPP3 PTPRS MACF1 LTBP2	2.02e-07	197	139	8	94a9603cbd3516fbcce871909693b88f20d41713
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL5A2 ABCA9 SVEP1 PHEX IGSF10 PLPP3 MACF1 LTBP2	2.10e-07	198	139	8	f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCell	343B-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SVEP1 PHEX IGSF10 AKAP9 PLPP3 PTPRS MACF1 LTBP2	2.18e-07	199	139	8	212e89d097753790061310373a1fafba773488b6
ToppCell	343B-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SVEP1 PHEX IGSF10 AKAP9 PLPP3 PTPRS MACF1 LTBP2	2.18e-07	199	139	8	14b676aa289c0578a37be32cec3ea285c79d97cc
ToppCell	medial-mesenchymal-Alveolar_Fibroblast\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL5A2 ABCA9 SVEP1 IGSF10 PLPP3 PTPRS MACF1 LTBP2	2.27e-07	200	139	8	c22cbfecee00183dd4be678f116ab9fd9ad0a4dd
ToppCell	Control_saline-Mesenchymal_fibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	TRHDE COL5A2 SYNE1 SVEP1 PHEX IGSF10 PLPP3 MACF1	2.27e-07	200	139	8	64ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCell	medial-2-mesenchymal-Alveolar_Fibroblast\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL5A2 ABCA9 SVEP1 IGSF10 PLPP3 PTPRS MACF1 LTBP2	2.27e-07	200	139	8	cc6062dac07916c29091fc6bee2b864d29e6525b
ToppCell	proximal-mesenchymal-Adventitial_Fibroblast\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL5A2 PAMR1 ABCA9 SVEP1 IGSF10 PLPP3 PTPRS LTBP2	2.27e-07	200	139	8	58c5870030192b337e7d883044948634fcd17d2c
ToppCell	proximal-mesenchymal-Adventitial_Fibroblast-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL5A2 PAMR1 ABCA9 SVEP1 IGSF10 PLPP3 PTPRS LTBP2	2.27e-07	200	139	8	05486d86868f6a93429226063cca270f00dd8714
ToppCell	medial-mesenchymal-Alveolar_Fibroblast-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL5A2 ABCA9 SVEP1 IGSF10 PLPP3 PTPRS MACF1 LTBP2	2.27e-07	200	139	8	5c0716bf375c8158f7dc2c82bf5eaf37af594dd0
ToppCell	proximal-3-mesenchymal-Adventitial_Fibroblast\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL5A2 PAMR1 ABCA9 SVEP1 IGSF10 PLPP3 PTPRS LTBP2	2.27e-07	200	139	8	869d45b71efd395d050873db5fee2ed0443d5e6f
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated\|COVID-19_Mild / Disease, condition lineage and cell class	SYNE1 HLA-G ARHGEF12 RNF213 HUWE1 EIF3CL MACF1 EIF3C	2.27e-07	200	139	8	2281debd86e5d92e8fe0397aec9ef670800f7471
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts\|Control_saline / Treatment groups by lineage, cell group, cell type	TRHDE COL5A2 SYNE1 SVEP1 PHEX IGSF10 PLPP3 MACF1	2.27e-07	200	139	8	a1fc74c1b27e104895910bc7cdce7ba33d30df7e
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	TRHDE COL5A2 SYNE1 SVEP1 PHEX IGSF10 PLPP3 MACF1	2.27e-07	200	139	8	bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE SPTA1 PKD1L2 GRM1 CSMD3 DNAH1 HYDIN	1.85e-06	184	139	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE SPTA1 PKD1L2 GRM1 CSMD3 DNAH1 HYDIN	1.85e-06	184	139	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE SPTA1 PKD1L2 GRM1 CSMD3 DNAH1 HYDIN	1.85e-06	184	139	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	TRHDE COL5A2 ABCA9 SVEP1 PTPRS MACF1 LTBP2	2.06e-06	187	139	7	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	RNF213 HUWE1 ZDHHC17 MCM9 MACF1 PRKDC CDK6	2.37e-06	191	139	7	9454f642c3621370fa23640b631301346b300950
ToppCell	RV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	TRHDE COL5A2 PAMR1 ABCA9 SVEP1 EYS PTPRS	2.37e-06	191	139	7	70c067c54084bfb02c29bab085f4defd477194fb
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A2 PAMR1 ABCA9 SVEP1 IGSF10 PLPP3 LTBP2	2.45e-06	192	139	7	c5f8e766453f87847b740d6988c524b3d0ef3765
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	COL5A2 FLT1 PAMR1 CSMD3 ABCA9 PHEX PLCL1	2.54e-06	193	139	7	cd45118ced91b10baed3b1068d4673ec99824b86
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TRHDE COL5A2 ABCA9 SVEP1 PHEX PTPRS MACF1	2.54e-06	193	139	7	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TRHDE COL5A2 ABCA9 SVEP1 PHEX PLPP3 PTPRS	2.62e-06	194	139	7	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TRHDE COL5A2 SYNE1 SVEP1 PHEX IGSF10 PTPRS	2.62e-06	194	139	7	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	LPS-antiTNF-Stromal_mesenchymal\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TRHDE COL5A2 SYNE1 SVEP1 PHEX IGSF10 PTPRS	2.62e-06	194	139	7	6e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPD2 HUWE1 AKAP9 CLTC FNIP1 MACF1 PCM1	2.72e-06	195	139	7	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPD2 HUWE1 AKAP9 CLTC FNIP1 MACF1 PCM1	2.72e-06	195	139	7	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	LPS_IL1RA_TNF\|World / Treatment groups by lineage, cell group, cell type	COL5A2 SYNE1 SVEP1 PHEX IGSF10 AKAP9 FZD2	2.90e-06	197	139	7	0a6550dce156fc81f15b1e7830d331ca50d87d06
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA9 SVEP1 IGSF10 PLPP3 PTPRS MACF1 LTBP2	2.90e-06	197	139	7	13896ec65ccda0b928c91d41112dc01b480036b7
ToppCell	proximal-mesenchymal-Alveolar_Fibroblast\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SVEP1 PHEX IGSF10 PLPP3 PTPRS MACF1 LTBP2	3.10e-06	199	139	7	7f4840ae6a888380feca722543e5e52783f3e35d
ToppCell	distal-mesenchymal-Alveolar_Fibroblast-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL5A2 ABCA9 SVEP1 IGSF10 PLPP3 MACF1 LTBP2	3.10e-06	199	139	7	28c1722deef3b8347371c7359be7c64b95780de3
ToppCell	proximal-3-mesenchymal-Alveolar_Fibroblast\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SVEP1 PHEX IGSF10 PLPP3 PTPRS MACF1 LTBP2	3.10e-06	199	139	7	301d02bbb37e6f1d24b6e865bc3fe3e91260eb30
ToppCell	proximal-mesenchymal-Alveolar_Fibroblast-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SVEP1 PHEX IGSF10 PLPP3 PTPRS MACF1 LTBP2	3.10e-06	199	139	7	9a16e519fb0651a7c4d8e05b931df4fb3b0eb3d1
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	COL5A2 SYNE1 SVEP1 PHEX IGSF10 PLPP3 MACF1	3.10e-06	199	139	7	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	(5)_Fibroblast-G\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	SVEP1 PHEX IGSF10 PLPP3 PTPRS MACF1 LTBP2	3.10e-06	199	139	7	b4a737575be9f8c65771832dd8cd25328d5dae0d
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL5A2 PAMR1 ABCA9 SVEP1 IGSF10 PLPP3 LTBP2	3.10e-06	199	139	7	0019cfaa586a450c2e4952d1184a540561c8d0ba
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	COL5A2 SYNE1 SVEP1 PHEX IGSF10 PLPP3 MACF1	3.10e-06	199	139	7	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	COL5A2 SYNE1 SVEP1 PHEX IGSF10 PLPP3 MACF1	3.10e-06	199	139	7	e1849505b92820a219c5a2c35492bdd55579fb48
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL5A2 ABCA9 SVEP1 IGSF10 PLPP3 MACF1 LTBP2	3.10e-06	199	139	7	66a79732caf2f04c09b4d9832377aa01ca477677
ToppCell	cellseq-Mesenchymal-Fibroblastic\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL5A2 ABCA9 SVEP1 IGSF10 PLPP3 MACF1 LTBP2	3.21e-06	200	139	7	8978867bf69c830b1e48cac2ad6b512dbe60f149
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FLT1 ARHGEF12 RNF213 NCKAP5 MACF1 NOTCH1 BRWD1	3.21e-06	200	139	7	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	COL5A2 SYNE1 SVEP1 PHEX IGSF10 PLPP3 MACF1	3.21e-06	200	139	7	b79628fd1386aa9a3b0e9fa81def0bc100c3c073
ToppCell	normal_Lung-Fibroblasts\|normal_Lung / Location, Cell class and cell subclass	COL5A2 PAMR1 ABCA9 SVEP1 IGSF10 PLPP3 PTPRS	3.21e-06	200	139	7	803cf7f1382d07220249029cd220233232027689
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	COL5A2 SYNE1 SVEP1 PHEX IGSF10 PLPP3 MACF1	3.21e-06	200	139	7	50ca6550998e461ef26dd670351060bd940765a8
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TRHDE COL5A2 ABCA9 SVEP1 PHEX PTPRS LTBP2	3.21e-06	200	139	7	e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	ABCA9 SVEP1 PHEX IGSF10 PTPRS MACF1 LTBP2	3.21e-06	200	139	7	aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	COL5A2 SYNE1 SVEP1 PHEX IGSF10 PLPP3 MACF1	3.21e-06	200	139	7	3bdba9612cd7c612b76aa9abecc4a6529aabfc1c
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABCA9 SVEP1 PHEX IGSF10 PTPRS MACF1 LTBP2	3.21e-06	200	139	7	a510deaada669e690329183e18df02870bd204b3
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	COL5A2 SYNE1 SVEP1 PHEX IGSF10 PLPP3 MACF1	3.21e-06	200	139	7	44a68bacdb3d5bf563bd35952176995850933a81
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TRHDE COL5A2 SYNE1 ABCA9 SVEP1 PLPP3 LTBP2	3.21e-06	200	139	7	3dd022e974fec7013ba18f333da63f58fbf2dd7c
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	COL5A2 SYNE1 SVEP1 PHEX IGSF10 PLPP3 MACF1	3.21e-06	200	139	7	dc61016c61729f69649cfb21f6264e685ce83dea
ToppCell	normal_Lung-Fibroblasts-COL14A1+_matrix_FBs\|normal_Lung / Location, Cell class and cell subclass	COL5A2 PAMR1 ABCA9 SVEP1 IGSF10 PLPP3 PTPRS	3.21e-06	200	139	7	ee3d06865a6300e1279edf6664320b71647f5efb
ToppCell	Biopsy_Control_(H.)-Mesenchymal-PLIN2+_Fibroblasts\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	COL5A2 PAMR1 ABCA9 SVEP1 PTPRS TET1 LTBP2	3.21e-06	200	139	7	cdaf462b1db29dab61038eeab5ddd3eef3386763
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TRHDE COL5A2 SYNE1 ABCA9 SVEP1 LTBP2 PLCL1	3.21e-06	200	139	7	58b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCA9 SVEP1 PHEX IGSF10 PTPRS MACF1 LTBP2	3.21e-06	200	139	7	dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Hsd11b1_Endou\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	COL5A2 SATB2 PAMR1 WNT4 JAML FMNL1	1.04e-05	158	139	6	c8af8964a140acb2987e3b4906d72c546108d229
ToppCell	356C-Fibroblasts-Fibroblast-H-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL5A2 PAMR1 DPYSL4 SVEP1 SV2A VAX2	1.48e-05	168	139	6	b5d74500bdac0d680ce7eb7afa0b867b8d85e6a4
ToppCell	356C-Fibroblasts-Fibroblast-H\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL5A2 PAMR1 DPYSL4 SVEP1 SV2A VAX2	1.48e-05	168	139	6	838ce47d4958ba12047882f97925eddd02f081c7
ToppCell	B_cells-pDCs\|World / Immune cells in Kidney/Urine in Lupus Nephritis	ZDHHC17 JAML WDFY4 PHEX PTPRS C4BPB	1.48e-05	168	139	6	dc8f94424f60ab56facdcffa969e7f3466ee1b6e
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTA1 CSMD3 DNAH1 LTBP2 HYDIN SPINK5	1.53e-05	169	139	6	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL5A2 H6PD SVEP1 PLPP3 MACF1 DENND5A	1.58e-05	170	139	6	7fa022471e14ac8a3bc147c793368a4d56a8e591
ToppCell	normal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells\|B_lymphocytes / Location, Cell class and cell subclass	LZTR1 JAML FRMD4B PHEX IGSF10 PTPRS	1.92e-05	176	139	6	d6e660df92a3d7dd5732171ee623763faf108476
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-like-AT1_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SVEP1 CNNM4 AMOT AP5Z1 ZNF616 ZNF830	1.98e-05	177	139	6	164ffbbf798defa3728197deb1a14b661490e525
ToppCell	COVID-19_Mild-NK_activated\|COVID-19_Mild / Disease condition and Cell class	SYNE1 HLA-G RNF213 EIF3CL MACF1 EIF3C	2.39e-05	183	139	6	22bd05135906d0ecc4ba8c2e0a666093d1bf3b8f
ToppCell	343B-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	NCKAP5 FRMD4B CLTC SPRED1 LTBP2 CDK6	2.62e-05	186	139	6	9673367cb53bafb873a01ef6bda11d9f392ce648
ToppCell	metastatic_Lymph_Node-Fibroblasts-COL14A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	ZDHHC17 ABCA9 CNNM4 ERMAP EIF3C ARHGEF4	2.62e-05	186	139	6	6259f0f2d5bc863782d09a901d6be2f387d1f074
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Parm1-Excitatory_Neuron.Slc17a7.Parm1.Ndnf_(Deep_layer_pyramidal_cells--layer_5)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	GLB1L3 SKOR1 MUC2 HYDIN	2.83e-05	56	139	4	64ccf87f1baf014924dd42a4eb5e7a3e99b365dd
ToppCell	droplet-Tongue-nan-24m-Epithelial-filiform\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 KRT34 KRT35 KRT39 PLPP3 KRT36	2.95e-05	190	139	6	86ab845a7fae2111c0b01e1aec235e19c4c0ef5c
ToppCell	droplet-Tongue-nan-3m-Epithelial-filiform\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 KRT34 KRT35 KRT39 PLPP3 KRT36	2.95e-05	190	139	6	251e3a33041023bfc4b547c7eb68cfb8f421636f
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TRHDE COL5A2 SVEP1 PHEX IGSF10 PLPP3	2.95e-05	190	139	6	841cd55861b43578d704418b9bc0af2e8b88323a
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	COL5A2 H6PD SVEP1 PLPP3 PTPRS MACF1	3.04e-05	191	139	6	3379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL5A2 PAMR1 NCKAP5 WNT4 IGSF10 PTPRS	3.04e-05	191	139	6	9214655dca96d766737c9f30b624d7fe7050342e
ToppCell	ASK440-Mesenchymal\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	PAMR1 ABCA9 SVEP1 IGSF10 PLPP3 LTBP2	3.04e-05	191	139	6	f12959eebb4167e1aa03de05d7711a702c58b3c9
ToppCell	ASK440-Mesenchymal-Fibroblast\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	PAMR1 ABCA9 SVEP1 IGSF10 PLPP3 LTBP2	3.04e-05	191	139	6	387296b5377ef6839f0812e5b3529a10b5f7d530
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL5A2 ABCA9 SVEP1 PTPRS MACF1 LTBP2	3.04e-05	191	139	6	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TRHDE COL5A2 SVEP1 PHEX IGSF10 PLPP3	3.13e-05	192	139	6	6f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCell	PND14-Mesenchymal-Mesenchymal_structural\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL5A2 H6PD SVEP1 PHEX IGSF10 MACF1	3.13e-05	192	139	6	25492568f9cbe097b7bb1db50d8b817c80ea87d7
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL5A2 ABCA9 SVEP1 PTPRS MACF1 LTBP2	3.13e-05	192	139	6	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	facs-Lung-3m-Mesenchymal\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL5A2 PAMR1 H6PD SVEP1 IGSF10 PLPP3	3.13e-05	192	139	6	8df15085b35b86f39debd933284cb703c5dd63c2
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TRHDE COL5A2 SVEP1 PHEX IGSF10 PLPP3	3.13e-05	192	139	6	3d0cb19f037f604253d7d728689aeaa94251e92b
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL5A2 H6PD SVEP1 PHEX IGSF10 MACF1	3.13e-05	192	139	6	de9c1536d5aee86f9c62acbc54ca8fa581c00f17
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)-D175\|Adult / Lineage, Cell type, age group and donor	FNIP2 WDFY4 EHBP1L1 PLPP3 SPRED1 DENND5A	3.13e-05	192	139	6	733491e932350e3c216a626cc49c3cd3fe970a82
ToppCell	PND28-Mesenchymal-Mesenchymal_structural\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL5A2 PAMR1 SVEP1 IGSF10 PLPP3 MACF1	3.22e-05	193	139	6	ec81c1afdae2e0433a22c8c1fa1c6232526ff7e7
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D231\|Adult / Lineage, Cell type, age group and donor	COL5A2 ABCA9 SVEP1 PHEX PTPRS LTBP2	3.22e-05	193	139	6	ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TRHDE COL5A2 SVEP1 PHEX IGSF10 PLPP3	3.22e-05	193	139	6	fb28717fadd06c3840636d25409ce80c9254bd34
ToppCell	LV-01._Fibroblast_I\|LV / Chamber and Cluster_Paper	COL5A2 PAMR1 ABCA9 SVEP1 PTPRS LTBP2	3.22e-05	193	139	6	dc17f3b9758936d428cf17f77a1ce6d4c479b165
Disease	retinopathy of prematurity (biomarker_via_orthology)	FLT1 NOS2 NOTCH1	1.91e-05	12	133	3	DOID:13025 (biomarker_via_orthology)
Disease	Malignant neoplasm of breast	FLT1 ABL1 SYNE1 RELA H6PD WNK1 CNNM4 AKAP9 NUP133 MACF1 ARHGEF4 USP54 ZNHIT2 NOS2 NOTCH1	1.04e-04	1074	133	15	C0006142
Disease	mucositis (biomarker_via_orthology)	MUC2 NOS2	2.00e-04	5	133	2	DOID:0080178 (biomarker_via_orthology)
Disease	response to bronchodilator, response to corticosteroid	CSMD3 ZNF616	2.00e-04	5	133	2	GO_0031960, GO_0097366
Disease	angina pectoris	FLT1 ARHGEF12 RNF213 EHBP1L1 PLPP3	2.62e-04	125	133	5	EFO_0003913
Disease	Colorectal Carcinoma	SATB2 SYNE1 GRM1 WNK1 CSMD3 ABCA9 GJD4 OSBP AKAP9 PTPRS FBXL2	3.50e-04	702	133	11	C0009402
Disease	interleukin 8 measurement, cerebrospinal fluid biomarker measurement	SATB2 PLCL1	4.17e-04	7	133	2	EFO_0006794, EFO_0008191
Disease	Hepatic Insufficiency	RELA NOS2	7.11e-04	9	133	2	C1306571
Disease	colitis (biomarker_via_orthology)	RELA MUC2 NOS2	9.04e-04	42	133	3	DOID:0060180 (biomarker_via_orthology)
Disease	Marfan Syndrome	LTBP2 NOS2	1.08e-03	11	133	2	C0024796
Disease	bipolar disorder	KIF18A PGAP3 SYNE1 HUWE1 SVEP1 CNNM4 RHEBL1 NCAN PLCL1	1.25e-03	577	133	9	MONDO_0004985
Disease	xanthine measurement	KSR2 EYS	1.52e-03	13	133	2	EFO_0010548
Disease	Glioblastoma Multiforme	LZTR1 STKLD1 NOTCH1 CDK6	1.63e-03	111	133	4	C1621958
Disease	Childhood Acute Lymphoblastic Leukemia	ABL1 NOTCH1 CDK6	1.68e-03	52	133	3	C0023452
Disease	RASopathy	LZTR1 SPRED1	2.04e-03	15	133	2	cv:C5555857
Disease	alkaline phosphatase measurement	PGAP3 WNT4 PHEX RSBN1 CCM2L MACF1 LTBP2 PLCL1 STKLD1 USP48 NOTCH1 PDCD1LG2	2.18e-03	1015	133	12	EFO_0004533
Disease	central nervous system disease (implicated_via_orthology)	SMARCA5 SMARCA1	2.32e-03	16	133	2	DOID:331 (implicated_via_orthology)
Disease	Malignant neoplasm of skin	FLT1 RELA NOTCH1	2.42e-03	59	133	3	C0007114
Disease	Skin Neoplasms	FLT1 RELA NOTCH1	2.42e-03	59	133	3	C0037286
Disease	cystic fibrosis (is_marker_for)	HLA-G MUC2 NOS2	2.79e-03	62	133	3	DOID:1485 (is_marker_for)
Disease	rheumatoid arthritis, ACPA-positive rheumatoid arthritis, rheumatoid factor seropositivity measurement	WDFY4 RSBN1 CDK6	2.92e-03	63	133	3	EFO_0000685, EFO_0007791, EFO_0009459
Disease	coronary artery disease	VPS11 FLT1 KSR2 ARHGEF12 RNF213 SVEP1 IGSF10 RSBN1 EHBP1L1 PLPP3 PLCL1 DENND5A USP48	2.94e-03	1194	133	13	EFO_0001645
Disease	cholangiocarcinoma (is_marker_for)	MUC2 NOS2 NOTCH1	3.05e-03	64	133	3	DOID:4947 (is_marker_for)
Disease	response to methotrexate, neurotoxicity	MACF1 PLCL1	3.28e-03	19	133	2	EFO_0011057, GO_0031427
Disease	Diabetes Mellitus, Non-Insulin-Dependent	GPD2 KSR2 RELA USP48 NOS2	3.33e-03	221	133	5	C0011860
Disease	Neoplastic Cell Transformation	SATB2 RELA NOS2 NOTCH1	3.67e-03	139	133	4	C0007621
Disease	bipolar I disorder	SYNE1 CNNM4 RHEBL1 NCAN	3.87e-03	141	133	4	EFO_0009963

Protein segments in the cluster

Peptide	Gene	Start	Entry
EVNVEIACRNATRYV	TRHDE	166	Q9UKU6
LNCLEQRIQEQGVEY	AKAP9	3061	Q99996
RNLRQELEGCYEKVA	AMOT	446	Q4VCS5
QCYSEVRREDGIQAE	ALG13	1031	Q9NP73
NERERQRVKCVNEGY	ASCL5	161	Q7RTU5
QGEERITCIQVENRY	CSMD3	1561	Q7Z407
DQRNQRLEVDYSIGR	COPS7A	146	Q9UBW8
ELYRDLDRCSNQGIE	ABCA9	761	Q8IUA7
LRTIFGNIEDIYRCQ	ARHGEF4	326	Q9NR80
LCRADQQYECVAEIG	CDK6	6	Q00534
VAFEYCQRLIEQSNR	AP5Z1	296	O43299
INYGADVNLRCANER	ASB14	171	A6NK59
YNDATQVRDCRLVGL	AMY2B	166	P19961
QIIYGDQSIECVDRA	CCM2L	326	Q9NUG4
YGLVQRCVIIQKDDN	ARHGEF12	66	Q9NZN5
LLAIYCRNEAGQEEV	ATF5	161	Q9Y2D1
EIARVENSYGQERRC	RHEBL1	166	Q8TAI7
QVQVRDEGQYQCIII	PDCD1LG2	91	Q9BQ51
RVIQCYIQYGNEEQR	PUM3	181	Q15397
RQRYVEKDGRCNVQQ	KCNJ9	21	Q92806
CEAANVAEQRRAYLE	HLA-G	171	P17693
TEIGVRDFCDVQRYN	NOS2	376	P35228
LIGLYICEENRRANE	NUP133	1031	Q8WUM0
RGLERLELYDCQQVT	FBXL2	366	Q9UKC9
VENECYQVFLDRINR	TOR1AIP2	31	Q9H496
IRCDLERQNQEYQVL	KRT40	361	Q6A162
VRGSIVYLEIDNRQC	NOTCH1	1671	P46531
LNEVRNYLSCDVEVR	GPD2	376	P43304
RLEQLCRQYIEASVD	LZTR1	561	Q8N653
GLQRYERNICEIDTE	EYS	631	Q5T1H1
CVLQEYQQFRENVLR	NEIL1	136	Q96FI4
EYLRRVQIEAAQCPD	GEMIN2	51	O14893
AEIRCALERQNQEYE	KRT39	366	Q6A163
NYIRNNELICPREND	SPINK5	921	Q9NQ38
DCRYLRILVENQGRV	GLB1L3	501	Q8NCI6
LNCLFQNREEIRQEY	KIF18A	426	Q8NI77
ERVTSYLQRCGEQVD	LRRC75A	191	Q8NAA5
VEKYGANREECARLN	KSR2	131	Q6VAB6
ETECRYALQLQQIQG	KRT13	351	P13646
AYVQCNEDNVERDIQ	DYNC2I1	531	Q8WVS4
GRPVYQDEQERFVCN	GJD4	41	Q96KN9
LDCRYNREGEQEIHV	PCM1	601	Q15154
YLEAGDVVVRQEERC	MUC2	726	Q02817
GYNADVICLQEVDRA	PDE12	341	Q6L8Q7
QERVVCNERFSEDGY	FZD2	301	Q14332
QYVCAELQALEQEQR	EHBP1L1	1361	Q8N3D4
LDNCVEVGRIANTYN	KLHL9	151	Q9P2J3
LQCLREAAERGNVYA	LRP2BP	231	Q9P2M1
CQYETLVENNRRDAE	KRT35	271	Q92764
IACRGENADYVEQAI	OVOS2	701	Q6IE36
REYNLEQQRRAQCET	HUWE1	3646	Q7Z6Z7
DRLEENGYRSLCEQV	OSBP	506	P22059
YIQECEGLIRQLQVD	MACF1	476	Q9UPN3
RGQELENRAEQCLYV	PKD1L2	641	Q7Z442
LRTPRDENVYECVAQ	PTPRS	96	Q13332
EAQVCAIIERVQRYL	EIF3C	476	Q99613
QEIENAINEYRIRCG	FRMD4B	546	Q9Y2L6
AYENREVINVCSDLR	DNAH1	1281	Q9P2D7
NLNVEYNIFEGVECR	DPYSL4	426	O14531
DEAQVCAIIERVQRY	EIF3CL	476	B5ME19
QRVEIQDRGQYLCSA	IGSF10	1711	Q6WRI0
QILAERIQLSDCYRG	HYDIN	2216	Q4G0P3
RQLAQREAAEVCEYA	HEATR5B	1091	Q9P2D3
VYQDCERRGRNVLFD	FNIP1	46	Q8TF40
VYQDCDRRGRQVLFD	FNIP2	51	Q9P278
AEGLSQEIRNEICYN	COQ8A	456	Q8NI60
GNLLDYLRECNRQEV	ABL1	321	P00519
YLRECNRQEVNAVVL	ABL1	326	P00519
EDRYYLVGVQEQQCV	C4BPB	166	P20851
ERQRVKCVNEGYAQL	ASCL3	101	Q9NQ33
EGNIRFRYIVLQDTC	COL5A2	1436	P05997
QCDEEELRIYQLNIQ	DENND5A	501	Q6IQ26
CRRAAQVLVQELEQY	BRWD1	31	Q9NSI6
VYAQLCNVARIEAER	LTBP2	1631	Q14767
GQYEVVKECVQRREL	ANKS3	46	Q6ZW76
NLGAERICQAIEAYD	FMNL1	726	O95466
DLQAIDRAYRIGQCR	ERCC6L2	621	Q5T890
KCGEIREQYGIQRVE	GRM1	66	Q13255
RLCAEEDQGAQIYAR	H6PD	661	O95479
EAARREQRYQEQGGE	DBNL	216	Q9UJU6
NYLIDCERRLERGQD	CKMT1A	391	P12532
RCQYEALVENNRRDV	KRT36	266	O76013
RCDLERQNQEYQVLL	KRT36	366	O76013
YTGQRCENLLEERNC	PAMR1	266	Q6UXH9
EPVYRDCVLQCEEQN	PGAP3	26	Q96FM1
CRDYQEIKIQEQVQR	MCM9	196	Q9NXL9
VRLEDQGSYRCLIQV	ERMAP	116	Q96PL5
LCYRELAAQQRQEEA	PLEKHF1	206	Q96S99
EGIRYARIQLCDNDI	RSBN1	661	Q5VWQ0
CNELDQERKARYAIQ	SKOR1	916	P84550
RENVYEELRQCVRNA	SMARCA1	981	P28370
LEEQRQEQALQRYRC	SYNE1	6076	Q8NF91
QEQALQRYRCEADEL	SYNE1	6081	Q8NF91
EYGIQAEERQRVIDC	SYNM	261	O15061
RCDLERQNQEYQVLL	KRT34	371	O76011
QREQYERCLDEVANQ	NCKAP5	206	O14513
IQNYRCRGDDSKVQE	PLPP3	176	O14495
VQEADQGTYICEIRL	JAML	106	Q86YT9
GLYRCQVVRGIEDEQ	NCAN	136	O14594
RVERENLSDYCVLGQ	SATB2	236	Q9UPW6
EADQGLCRQIRHQYR	NSMCE4A	76	Q9NXX6
YELEGNRERVCQENR	SVEP1	3271	Q4LDE5
EELAQQYEAILRECG	SV2A	146	Q7L0J3
QNQVEYENVARECRL	TET1	1636	Q8NFU7
YERGQCDLELINVCN	CLTC	921	Q00610
IVQNCGTEKERRYAR	CNNM4	216	Q6P4Q7
NCQYQVEEGRETVQE	RNF213	4936	Q63HN8
DYNGEQKQIRLCREL	PLCL1	571	Q15111
QYRQVISVCERHGEQ	VPS11	701	Q9H270
LQKVQTEGRLYECNE	ZNF616	151	Q08AN1
NEYGARQCEARLEVR	SPEG	946	Q15772
CQDRALLVNNAYRGL	STKLD1	556	Q8NE28
DQDLACTVLQIEYRG	SERPINA11	256	Q86U17
SIGIIRCYNDEQDNA	WDHD1	451	O75717
VYCQERFNHEENVRG	SPRED1	336	Q7Z699
EENDQLIRCIVEYQN	SS18L2	26	Q9UHA2
EDFVSCIENYRRRGQ	WDFY4	2221	Q6ZS81
VRCNSYRPEAAREQV	PHEX	691	P78562
EGRVVEVNQYANECA	SPTA1	211	P02549
EDKCLQRQNRYDGQV	UBA1	441	P22314
ALTVRGFQENECRDY	VPS41	321	P49754
CNNVLYIRGVEEEEE	SNRPF	66	P62306
RLACDVDQVTRQLYE	PRKDC	971	P78527
GELCQRLVRNVEYYQ	RABAC1	61	Q9UI14
ERCRELVEAGYDVRQ	ZDHHC17	71	Q8IUH5
LQVYREQADSCREQL	TRIM14	141	Q14142
CAENFYRDQVLGELR	ZNHIT2	41	Q9UHR6
FQRCQYVVGRERTEL	VAX2	121	Q9UIW0
LDRQIGEIDEQIECY	ZNF830	301	Q96NB3
SVRRGAQLAIEECQY	WNT4	66	P56705
AQLAIEECQYQFRNR	WNT4	71	P56705
IEGCIRQNKDERYSI	WNK1	456	Q9H4A3
KENVYDELRQCIRNS	SMARCA5	966	O60264
CRARNVYTGEEILQK	FLT1	636	P17948
RIQEGSRDNNEYIAR	RNF145	621	Q96MT1
VKACQGQYETIERLR	TBC1D10A	321	Q9BXI6
EEQRGDYDLNAVRLC	RELA	146	Q04206
EGLLCQQQRDLREYT	USP48	846	Q86UV5
QEDSPGVRQRVYECQ	ZNF32	66	P17041
DQACDRIYRVGQQKD	TTF2	1096	Q9UNY4
CGEDEQYSAENLRRI	USP54	1401	Q70EL1
QTLEEQLGYNLREVC	ZSCAN23	166	Q3MJ62
NEQRLQGLYCDVSVV	NACC1	21	Q96RE7