Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity	ALG10B ALG10	4.27e-05	2	131	2	GO:0106073
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	SMG1 CDC42BPA PRAG1 CDC42BPB ARAF AATK CIITA COQ8A PIK3C2A FAM20B PIP5K1A ULK4 ATM G6PC1	2.36e-04	709	131	14	GO:0016773
GeneOntologyMolecularFunction	triplex DNA binding	DDX11 DDX11L8	2.54e-04	4	131	2	GO:0045142
Domain	ARM-type_fold	PDS5B SMG1 PKP4 KPNA6 CTIF ITPR1 PIK3C2A ULK4 PDS5A RIPOR1 ATM CTNND1 CTNND2 UNC79 HTT	1.16e-08	339	128	15	IPR016024
Domain	Plakophilin/d_Catenin	PKP4 CTNND1 CTNND2	1.08e-05	7	128	3	IPR028435
Domain	ARM-like	PDS5B SMG1 PKP4 KPNA6 ULK4 PDS5A RIPOR1 CTNND1 CTNND2 HTT	1.71e-05	270	128	10	IPR011989
Domain	-	PDS5B PKP4 KPNA6 ULK4 PDS5A RIPOR1 CTNND1 CTNND2 HTT	2.26e-05	222	128	9	1.25.10.10
Domain	Alg10	ALG10B ALG10	4.66e-05	2	128	2	IPR016900
Domain	KELK	CDC42BPA CDC42BPB	4.66e-05	2	128	2	IPR031597
Domain	DIE2_ALG10	ALG10B ALG10	4.66e-05	2	128	2	PF04922
Domain	KELK	CDC42BPA CDC42BPB	4.66e-05	2	128	2	PF15796
Domain	ATM/Tel1	SMG1 ATM	4.66e-05	2	128	2	IPR015519
Domain	Arm	PKP4 KPNA6 CTNND1 CTNND2	5.74e-05	31	128	4	PF00514
Domain	HEAT_REPEAT	PDS5B SMG1 ULK4 PDS5A HTT	1.18e-04	70	128	5	PS50077
Domain	PI3/4_kinase_CS	SMG1 PIK3C2A ATM	1.35e-04	15	128	3	IPR018936
Domain	ARM_REPEAT	PKP4 KPNA6 CTNND1 CTNND2	1.59e-04	40	128	4	PS50176
Domain	ARM	PKP4 KPNA6 CTNND1 CTNND2	1.59e-04	40	128	4	SM00185
Domain	-	SMG1 PIK3C2A ATM	1.65e-04	16	128	3	1.10.1070.11
Domain	PI3Kc	SMG1 PIK3C2A ATM	1.65e-04	16	128	3	SM00146
Domain	PI3_PI4_kinase	SMG1 PIK3C2A ATM	2.38e-04	18	128	3	PF00454
Domain	PI3_4_KINASE_1	SMG1 PIK3C2A ATM	2.38e-04	18	128	3	PS00915
Domain	PI3_4_KINASE_2	SMG1 PIK3C2A ATM	2.38e-04	18	128	3	PS00916
Domain	PI3/4_kinase_cat_dom	SMG1 PIK3C2A ATM	2.38e-04	18	128	3	IPR000403
Domain	PI3_4_KINASE_3	SMG1 PIK3C2A ATM	2.38e-04	18	128	3	PS50290
Domain	Myotonic_dystrophy_kinase_coil	CDC42BPA CDC42BPB	2.77e-04	4	128	2	IPR014930
Domain	Myotonic_dystrophy_kinase_coil	CDC42BPA CDC42BPB	2.77e-04	4	128	2	PD011252
Domain	DMPK_coil	CDC42BPA CDC42BPB	2.77e-04	4	128	2	PF08826
Domain	BTB	LZTR1 NACC1 ZBTB37 RHOBTB2 ZBTB21 KBTBD12	2.86e-04	131	128	6	PF00651
Domain	Armadillo	PKP4 KPNA6 CTNND1 CTNND2	2.99e-04	47	128	4	IPR000225
Domain	FATC	SMG1 ATM	4.60e-04	5	128	2	PF02260
Domain	DMAP_binding	DIP2B DIP2A	4.60e-04	5	128	2	PF06464
Domain	DMAP1-bd	DIP2B DIP2A	6.87e-04	6	128	2	IPR010506
Domain	TNF_rcpt--assoc_TRAF	TRAF3 TRAF6	6.87e-04	6	128	2	IPR012227
Domain	FAT	SMG1 ATM	6.87e-04	6	128	2	PS51189
Domain	FATC	SMG1 ATM	6.87e-04	6	128	2	PS51190
Domain	FATC_dom	SMG1 ATM	6.87e-04	6	128	2	IPR003152
Domain	PIK_FAT	SMG1 ATM	6.87e-04	6	128	2	IPR014009
Domain	DMAP_binding	DIP2B DIP2A	6.87e-04	6	128	2	SM01137
Domain	FATC	SMG1 ATM	6.87e-04	6	128	2	SM01343
Domain	BTB	LZTR1 NACC1 ZBTB37 RHOBTB2 ZBTB21 KBTBD12	8.26e-04	160	128	6	PS50097
Domain	zf-TRAF	TRAF3 TRAF6	1.27e-03	8	128	2	PF02176
Domain	BTB	LZTR1 NACC1 ZBTB37 RHOBTB2 ZBTB21 KBTBD12	1.51e-03	180	128	6	SM00225
Domain	cNMP	KCNH3 PNPLA7 RAPGEF2	1.61e-03	34	128	3	SM00100
Domain	cNMP_binding	KCNH3 PNPLA7 RAPGEF2	1.61e-03	34	128	3	PF00027
Domain	BTB/POZ_dom	LZTR1 NACC1 ZBTB37 RHOBTB2 ZBTB21 KBTBD12	1.74e-03	185	128	6	IPR000210
Domain	cNMP-bd_dom	KCNH3 PNPLA7 RAPGEF2	1.75e-03	35	128	3	IPR000595
Domain	CNMP_BINDING_3	KCNH3 PNPLA7 RAPGEF2	1.75e-03	35	128	3	PS50042
Domain	SKP1/BTB/POZ	LZTR1 NACC1 ZBTB37 RHOBTB2 ZBTB21 KBTBD12	1.94e-03	189	128	6	IPR011333
Domain	cNMP-bd-like	KCNH3 PNPLA7 RAPGEF2	2.23e-03	38	128	3	IPR018490
Domain	MATH	TRAF3 TRAF6	2.94e-03	12	128	2	PS50144
Domain	Znf_TRAF	TRAF3 TRAF6	2.94e-03	12	128	2	IPR001293
Domain	MATH/TRAF_dom	TRAF3 TRAF6	2.94e-03	12	128	2	IPR002083
Domain	MATH	TRAF3 TRAF6	2.94e-03	12	128	2	SM00061
Domain	MATH	TRAF3 TRAF6	2.94e-03	12	128	2	PF00917
Domain	Kelch_2	LZTR1 KLHDC3	3.46e-03	13	128	2	IPR011498
Domain	ZF_TRAF	TRAF3 TRAF6	3.46e-03	13	128	2	PS50145
Domain	Kelch_2	LZTR1 KLHDC3	3.46e-03	13	128	2	PF07646
Domain	Gelsolin	FLII SEC24C	4.02e-03	14	128	2	PF00626
Domain	Gelsolin-like_dom	FLII SEC24C	4.02e-03	14	128	2	IPR007123
Domain	-	TRAF3 TRAF6	4.02e-03	14	128	2	3.90.890.10
Domain	-	TRAF3 TRAF6	4.02e-03	14	128	2	2.60.210.10
Domain	CNH	CDC42BPA CDC42BPB	4.02e-03	14	128	2	SM00036
Domain	Kinase-like_dom	SMG1 CDC42BPA PRAG1 CDC42BPB ARAF AATK COQ8A PIK3C2A ULK4 ATM	4.16e-03	542	128	10	IPR011009
Domain	-	KCNH3 PNPLA7 RAPGEF2	4.34e-03	48	128	3	2.60.120.10
Domain	-	LZTR1 KLHDC3 KBTBD12	4.34e-03	48	128	3	2.120.10.80
Domain	CNH	CDC42BPA CDC42BPB	4.62e-03	15	128	2	PF00780
Domain	CNH	CDC42BPA CDC42BPB	4.62e-03	15	128	2	PS50219
Domain	CNH_dom	CDC42BPA CDC42BPB	4.62e-03	15	128	2	IPR001180
Domain	RmlC-like_jellyroll	KCNH3 PNPLA7 RAPGEF2	5.15e-03	51	128	3	IPR014710
Domain	SIAH-type	TRAF3 TRAF6	5.25e-03	16	128	2	IPR013323
Domain	PBD	CDC42BPA CDC42BPB	5.25e-03	16	128	2	SM00285
Domain	PPIase_FKBP	FKBP6 TTC9	5.93e-03	17	128	2	IPR023566
Domain	LRR_6	LRRC42 RNH1 CIITA	6.36e-03	55	128	3	PF13516
Domain	Kelch-typ_b-propeller	LZTR1 KLHDC3 KBTBD12	6.36e-03	55	128	3	IPR015915
Pubmed	The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.	DIP2B PKP4 CTIF PRAG1 RNH1 PIK3C2A CTNND1 CTNND2 WDFY1	2.00e-07	218	135	9	33378226
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DIP2B DIP2A NWD2 AATK CTNND1 RAPGEF2	1.19e-06	87	135	6	12465718
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	LZTR1 NACC1 CECR2 PKP4 KPNA6 ARAF DMAP1 ZNF469 RNH1 COQ8A ANAPC1 ZBTB21 TTC39A OSMR RAPGEF2 VPS53 NOTCH2	1.65e-06	1116	135	17	31753913
Pubmed	p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas.	PKP4 CTNND1 CTNND2 MUC1	1.82e-06	23	135	4	25523391
Pubmed	DIPA-family coiled-coils bind conserved isoform-specific head domain of p120-catenin family: potential roles in hydrocephalus and heterotopia.	PKP4 CTNND1 CTNND2	1.98e-06	7	135	3	25009281
Pubmed	Ang2/fat-free is a conserved subunit of the Golgi-associated retrograde protein complex.	VPS54 EXOC2 VPS53	3.16e-06	8	135	3	20685960
Pubmed	The Erbin PDZ domain binds with high affinity and specificity to the carboxyl termini of delta-catenin and ARVCF.	PKP4 CTNND1 CTNND2	3.16e-06	8	135	3	11821434
Pubmed	CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.	ARAF ITPR1 COQ8A ATM EXOC2 HTT	3.40e-06	104	135	6	31240132
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	DIP2B FLII PDE2A TRAF3 NACC1 PKP4 CDC42BPB SEC24C ANAPC1 ZBTB21 CTNND1 CTNND2 RAPGEF2 CABIN1 UNC79	5.42e-06	963	135	15	28671696
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FLII PDE2A LZTR1 CDC42BPA FHIP1B PRAG1 CDC42BPB KCNH3 DIP2A AATK ULK4 RIPOR1 CABIN1 D2HGDH NOTCH2 HTT	6.48e-06	1105	135	16	35748872
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SMG1 DIP2B PKP4 ARAF ALG10B ITPR1 TGM2 DIP2A NUP155 COQ8A PIP5K1A DDX11L8	9.39e-06	650	135	12	38777146
Pubmed	SMG1 heterozygosity exacerbates haematopoietic cancer development in Atm null mice by increasing persistent DNA damage and oxidative stress.	SMG1 ATM	1.50e-05	2	135	2	31565865
Pubmed	Targeting ATM ameliorates mutant Huntingtin toxicity in cell and animal models of Huntington's disease.	ATM HTT	1.50e-05	2	135	2	25540325
Pubmed	Tumor necrosis factor receptor-associated factor 6 (TRAF6) associates with huntingtin protein and promotes its atypical ubiquitination to enhance aggregate formation.	TRAF6 HTT	1.50e-05	2	135	2	21454471
Pubmed	Canonical and truncated transglutaminase-2 regulate mucin-1 expression and androgen independency in prostate cancer cell lines.	TGM2 MUC1	1.50e-05	2	135	2	37160910
Pubmed	Cloning and chromosomal localization of human Cdc42-binding protein kinase beta.	CDC42BPA CDC42BPB	1.50e-05	2	135	2	10198171
Pubmed	PDS5 proteins are required for proper cohesin dynamics and participate in replication fork protection.	PDS5B PDS5A	1.50e-05	2	135	2	31757807
Pubmed	Genetic deletion of transglutaminase 2 does not rescue the phenotypic deficits observed in R6/2 and zQ175 mouse models of Huntington's disease.	TGM2 HTT	1.50e-05	2	135	2	24955833
Pubmed	hSMG-1 and ATM sequentially and independently regulate the G1 checkpoint during oxidative stress.	SMG1 ATM	1.50e-05	2	135	2	18332866
Pubmed	Type 2 transglutaminase differentially modulates striatal cell death in the presence of wild type or mutant huntingtin.	TGM2 HTT	1.50e-05	2	135	2	17403029
Pubmed	Exploring electrostatic interactions of relaxin family peptide receptor 3 and 4 with ligands using a NanoBiT-based binding assay.	RXFP3 RXFP4	1.50e-05	2	135	2	30684458
Pubmed	Delta-catenin regulates spine and synapse morphogenesis and function in hippocampal neurons during development.	CTNND1 CTNND2	1.50e-05	2	135	2	19403811
Pubmed	PDS5A and PDS5B in Cohesin Function and Human Disease.	PDS5B PDS5A	1.50e-05	2	135	2	34070827
Pubmed	Loss of vps54 function leads to vesicle traffic impairment, protein mis-sorting and embryonic lethality.	VPS54 VPS53	1.50e-05	2	135	2	23708095
Pubmed	Huntingtin is a scaffolding protein in the ATM oxidative DNA damage response complex.	ATM HTT	1.50e-05	2	135	2	28017939
Pubmed	Characterization of the interaction of phorbol esters with the C1 domain of MRCK (myotonic dystrophy kinase-related Cdc42 binding kinase) alpha/beta.	CDC42BPA CDC42BPB	1.50e-05	2	135	2	18263588
Pubmed	δ-Catenin Promotes Bevacizumab-Induced Glioma Invasion.	CTNND1 CTNND2	1.50e-05	2	135	2	30872378
Pubmed	Beyond regulation of cell adhesion: local control of RhoA at the cleavage furrow by the p0071 catenin.	PKP4 CTNND1	1.50e-05	2	135	2	17264675
Pubmed	HSV infection induces production of ROS, which potentiate signaling from pattern recognition receptors: role for S-glutathionylation of TRAF3 and 6.	TRAF3 TRAF6	1.50e-05	2	135	2	21949653
Pubmed	Mutations of the Huntington's disease protein impact on the ATM-dependent signaling and repair pathways of the radiation-induced DNA double-strand breaks: corrective effect of statins and bisphosphonates.	ATM HTT	1.50e-05	2	135	2	24277524
Pubmed	Identification and localization of a neurally expressed member of the plakoglobin/armadillo multigene family.	PKP4 CTNND2	1.50e-05	2	135	2	9342840
Pubmed	Interactions between MUC1 and p120 catenin regulate dynamic features of cell adhesion, motility, and metastasis.	CTNND1 MUC1	1.50e-05	2	135	2	24371222
Pubmed	Tissue transglutaminase selectively modifies proteins associated with truncated mutant huntingtin in intact cells.	TGM2 HTT	1.50e-05	2	135	2	11442349
Pubmed	Pharmacological characterization of relaxin-3/INSL7 receptors GPCR135 and GPCR142 from different mammalian species.	RXFP3 RXFP4	1.50e-05	2	135	2	15367576
Pubmed	Cigarette smoke disrupts the integrity of airway adherens junctions through the aberrant interaction of p120-catenin with the cytoplasmic tail of MUC1.	CTNND1 MUC1	1.50e-05	2	135	2	22833523
Pubmed	PDS5A and PDS5B differentially affect gene expression without altering cohesin localization across the genome.	PDS5B PDS5A	1.50e-05	2	135	2	35986423
Pubmed	Delta-catenin affects the localization and stability of p120-catenin by competitively interacting with E-cadherin.	CTNND1 CTNND2	1.50e-05	2	135	2	20108168
Pubmed	Intratumor δ-catenin heterogeneity driven by genomic rearrangement dictates growth factor dependent prostate cancer progression.	CTNND1 CTNND2	1.50e-05	2	135	2	32313227
Pubmed	Aberrant calcium signaling by transglutaminase-mediated posttranslational modification of inositol 1,4,5-trisphosphate receptors.	ITPR1 TGM2	1.50e-05	2	135	2	25201980
Pubmed	Heterozygous deficiency of delta-catenin impairs pathological angiogenesis.	CTNND1 CTNND2	1.50e-05	2	135	2	20048286
Pubmed	Identification of the domains in RXFP4 (GPCR142) responsible for the high affinity binding and agonistic activity of INSL5 at RXFP4 compared to RXFP3 (GPCR135).	RXFP3 RXFP4	1.50e-05	2	135	2	18582868
Pubmed	Loss of p120 catenin and links to mitotic alterations, inflammation, and skin cancer.	CTNND1 CTNND2	1.50e-05	2	135	2	18809907
Pubmed	A role for proteolytic regulation of δ-catenin in remodeling a subpopulation of dendritic spines in the rodent brain.	CTNND1 CTNND2	1.50e-05	2	135	2	29875160
Pubmed	δ-Catenin activates Rho GTPase, promotes lymphangiogenesis and growth of tumor metastases.	CTNND1 CTNND2	1.50e-05	2	135	2	25635825
Pubmed	Developmental functions of the P120-catenin sub-family.	CTNND1 CTNND2	1.50e-05	2	135	2	16942809
Pubmed	DMAP1 is an essential regulator of ATM activity and function.	DMAP1 ATM	1.50e-05	2	135	2	23318425
Pubmed	Mechanism for insulin-like peptide 5 distinguishing the homologous relaxin family peptide receptor 3 and 4.	RXFP3 RXFP4	1.50e-05	2	135	2	27404393
Pubmed	The Human DF3/MUC1 carcinoma-associated antigen signals nuclear localization of the catenin p120(ctn).	CTNND1 MUC1	1.50e-05	2	135	2	11181067
Pubmed	An ATM/TRIM37/NEMO Axis Counteracts Genotoxicity by Activating Nuclear-to-Cytoplasmic NF-κB Signaling.	TRAF6 NUP155 ATM	1.59e-05	13	135	3	30254148
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	DIP2B CDC42BPA PKP4 CDC42BPB DIP2A PIP5K1A CTNND1 STRA6 NOTCH2	1.77e-05	377	135	9	38117590
Pubmed	Systematic protein-protein interaction mapping for clinically relevant human GPCRs.	GJB6 RXFP3 FBXO17 SHISA4 F2RL1 AATK METTL9 RXFP4 CTNND2 NOTCH2 HTT PIGM	1.87e-05	697	135	12	28298427
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	DIP2B CDC42BPA G2E3 CTIF VPS54 ATP10A CDC42BPB COQ8A XPNPEP3 PIP5K1A RIPOR1 PLCB4 PNPLA7 CTNND1 RAPGEF2 NOTCH2 HTT DOP1A	1.93e-05	1489	135	18	28611215
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	FLII ZNF821 PDE2A TRAF6 SESN3 KPNA6 VPS54 CDC42BPB DMAP1 USP2 DIP2A ATM GFPT2 CTNND2 RAPGEF2 CABIN1	4.08e-05	1285	135	16	35914814
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SMG1 CDC42BPA CECR2 G2E3 DMAP1 NUP155 COQ8A FAM20B ZBTB21 FTO	4.39e-05	529	135	10	14621295
Pubmed	A point mutation in the gene for asparagine-linked glycosylation 10B (Alg10b) causes nonsyndromic hearing impairment in mice (Mus musculus).	ALG10B ALG10	4.48e-05	3	135	2	24303013
Pubmed	Increased expression of delta-catenin/neural plakophilin-related armadillo protein is associated with the down-regulation and redistribution of E-cadherin and p120ctn in human prostate cancer.	CTNND1 CTNND2	4.48e-05	3	135	2	16226102
Pubmed	Mef2 promotes spine elimination in absence of δ-catenin.	CTNND1 CTNND2	4.48e-05	3	135	2	23328440
Pubmed	Pom121 links two essential subcomplexes of the nuclear pore complex core to the membrane.	NUP155 NUP160	4.48e-05	3	135	2	20974814
Pubmed	MIP-T3, a novel protein linking tumor necrosis factor receptor-associated factor 3 to the microtubule network.	TRAF3 TRAF6	4.48e-05	3	135	2	10791955
Pubmed	CGG-repeat expansion in the DIP2B gene is associated with the fragile site FRA12A on chromosome 12q13.1.	DIP2B DIP2A	4.48e-05	3	135	2	17236128
Pubmed	Loss of ChlR1 helicase in mouse causes lethality due to the accumulation of aneuploid cells generated by cohesion defects and placental malformation.	DDX11 DDX11L8	4.48e-05	3	135	2	17611414
Pubmed	Induction of USP25 by viral infection promotes innate antiviral responses by mediating the stabilization of TRAF3 and TRAF6.	TRAF3 TRAF6	4.48e-05	3	135	2	26305951
Pubmed	Isolation of human delta-catenin and its binding specificity with presenilin 1.	CTNND1 CTNND2	4.48e-05	3	135	2	10208590
Pubmed	Pds5 Regulates Sister-Chromatid Cohesion and Chromosome Bi-orientation through a Conserved Protein Interaction Module.	PDS5B PDS5A	4.48e-05	3	135	2	28343969
Pubmed	Loss of δ-catenin function in severe autism.	CTNND1 CTNND2	4.48e-05	3	135	2	25807484
Pubmed	PAPIN. A novel multiple PSD-95/Dlg-A/ZO-1 protein interacting with neural plakophilin-related armadillo repeat protein/delta-catenin and p0071.	PKP4 CTNND2	4.48e-05	3	135	2	10896674
Pubmed	MUC1-C Oncoprotein Interacts Directly with ATM and Promotes the DNA Damage Response to Ionizing Radiation.	ATM MUC1	4.48e-05	3	135	2	20865059
Pubmed	Mammalian ChlR1 has a role in heterochromatin organization.	DDX11 DDX11L8	4.48e-05	3	135	2	21854770
Pubmed	Inducible ATP1B1 Upregulates Antiviral Innate Immune Responses by the Ubiquitination of TRAF3 and TRAF6.	TRAF3 TRAF6	4.48e-05	3	135	2	34011520
Pubmed	Deficiency of transcription factor RelB perturbs myeloid and DC development by hematopoietic-extrinsic mechanisms.	CIITA NOTCH2	4.48e-05	3	135	2	28348230
Pubmed	Calmodulin regulates transglutaminase 2 cross-linking of huntingtin.	TGM2 HTT	4.48e-05	3	135	2	14985437
Pubmed	Identification of novel NPRAP/δ-catenin-interacting proteins and the direct association of NPRAP with dynamin 2.	CTNND1 CTNND2	4.48e-05	3	135	2	22022388
Pubmed	Ataxia-Telangiectasia, Mutated (ATM)/Nuclear Factor κ light chain enhancer of activated B cells (NFκB) signaling controls basal and DNA damage-induced transglutaminase 2 expression.	TGM2 ATM	4.48e-05	3	135	2	22493284
Pubmed	Pds5B is required for cohesion establishment and Aurora B accumulation at centromeres.	PDS5B PDS5A	4.48e-05	3	135	2	24141881
Pubmed	Rictor Is a Novel Regulator of TRAF6/TRAF3 in Osteoclasts.	TRAF3 TRAF6	4.48e-05	3	135	2	34155681
Pubmed	Upregulation of δ-catenin is associated with poor prognosis and enhances transcriptional activity through Kaiso in non-small-cell lung cancer.	CTNND1 CTNND2	4.48e-05	3	135	2	21070476
Pubmed	Deubiquitinase USP47 attenuates virus-induced type I interferon signaling.	TRAF3 TRAF6	4.48e-05	3	135	2	37001379
Pubmed	The amnionless gene, essential for mouse gastrulation, encodes a visceral-endoderm-specific protein with an extracellular cysteine-rich domain.	TRAF3 CDC42BPB	4.48e-05	3	135	2	11279523
Pubmed	The ATM-related kinase, hSMG-1, bridges genome and RNA surveillance pathways.	SMG1 ATM	4.48e-05	3	135	2	15279777
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	TRAF3 PKP4 FBXO17 KIF24 ITPR1 PLCB4 CTNND1 FTO NOTCH2 WDFY1	4.90e-05	536	135	10	15840001
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	FLII TRAF3 CDC42BPB ARAF TGM2 NWD2 XPNPEP3 CTNND1 RAPGEF2	4.92e-05	430	135	9	32581705
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	TRAF3 PKP4 FBXO17 KIF24 ITPR1 PLCB4 CTNND1 FTO NOTCH2 WDFY1	5.06e-05	538	135	10	10512203
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	PDS5B DIP2B FLII NACC1 TBC1D2 SEC24C ANAPC1 ZBTB21 RIPOR1 ATM EXOC2 NOTCH2	5.17e-05	774	135	12	15302935
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	SMG1 KPNA6 DMAP1 ITPR1 NUP155 ANAPC1 GFPT2 CTNND1 NUP160	5.87e-05	440	135	9	34244565
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	FLII CDC42BPA DDX11 NBAS SEC24C CTNND1 VPS53	5.92e-05	251	135	7	29778605
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	PDS5B FLII DMAP1 NUP155 COQ8A ANAPC1 PIP5K1A PDS5A EXOC2 NUP160	7.05e-05	560	135	10	35241646
Pubmed	A proposed clinical application of a model of CO2 laser radiation induced damage craters.	VPS54 VPS53	8.93e-05	4	135	2	3172165
Pubmed	Severe acute respiratory syndrome coronavirus ORF3a protein activates the NLRP3 inflammasome by promoting TRAF3-dependent ubiquitination of ASC.	TRAF3 TRAF6	8.93e-05	4	135	2	31034780
Pubmed	YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction.	TRAF3 TRAF6	8.93e-05	4	135	2	17608743
Pubmed	UBXN1 interferes with Rig-I-like receptor-mediated antiviral immune response by targeting MAVS.	TRAF3 TRAF6	8.93e-05	4	135	2	23545497
Pubmed	A deficiency of lunatic fringe is associated with cystic dilation of the rete testis.	MUC1 NOTCH2	8.93e-05	4	135	2	18801836
Pubmed	Cholesterol depletion associated with Leishmania major infection alters macrophage CD40 signalosome composition and effector function.	TRAF3 TRAF6	8.93e-05	4	135	2	19198591
Pubmed	A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling.	TRAF3 TRAF6	8.93e-05	4	135	2	21041452
Pubmed	Blockade of CD40-TRAF2,3 or CD40-TRAF6 is sufficient to inhibit pro-inflammatory responses in non-haematopoietic cells.	TRAF3 TRAF6	8.93e-05	4	135	2	25051892
Pubmed	The armadillo protein p0071 regulates Rho signalling during cytokinesis.	PKP4 CTNND1	8.93e-05	4	135	2	17115030
Pubmed	The binding site for TRAF2 and TRAF3 but not for TRAF6 is essential for CD40-mediated immunoglobulin class switching.	TRAF3 TRAF6	8.93e-05	4	135	2	12354380
Pubmed	Suboptimal activation of protease-activated receptors enhances alpha2beta1 integrin-mediated platelet adhesion to collagen.	ITGA2 F2RL1	8.93e-05	4	135	2	19815553
Pubmed	RANKL cytokine enhances TNF-induced osteoclastogenesis independently of TNF receptor associated factor (TRAF) 6 by degrading TRAF3 in osteoclast precursors.	TRAF3 TRAF6	8.93e-05	4	135	2	28438834
Pubmed	PDS5 proteins regulate the length of axial elements and telomere integrity during male mouse meiosis.	PDS5B PDS5A	8.93e-05	4	135	2	32285610
Pubmed	GSK-3 phosphorylates delta-catenin and negatively regulates its stability via ubiquitination/proteosome-mediated proteolysis.	CTNND1 CTNND2	8.93e-05	4	135	2	19706605
Interaction	HAVCR2 interactions	DIP2B CDC42BPA PKP4 DIP2A PIK3C2A DDX11L8 PIGM	1.09e-06	83	130	7	int:HAVCR2
Interaction	GPR17 interactions	PDS5B FHIP1B NBAS ALG10 PDS5A ATM EXOC2 VPS53 HTT DOP1A	1.54e-05	283	130	10	int:GPR17
GeneFamily	Alpha-1,2-glucosyltransferases	ALG10B ALG10	2.13e-05	2	84	2	448
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	LZTR1 NACC1 ZBTB37 RHOBTB2 ZBTB21 KBTBD12	3.75e-05	134	84	6	861
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	PKP4 KPNA6 CTNND1 CTNND2	4.66e-05	43	84	4	409
GeneFamily	Relaxin family peptide receptors	RXFP3 RXFP4	1.27e-04	4	84	2	217
GeneFamily	TNF receptor associated factors	TRAF3 TRAF6	4.41e-04	7	84	2	1056
Coexpression	JOHNSTONE_PARVB_TARGETS_3_UP	FLII ITGA2 PRAG1 ARAF TGM2 TMC8 RIPOR1 ATM GFPT2 OSMR CTNND1 NOTCH2	2.63e-06	433	135	12	M2240
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-large_intestine_goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A DZIP1L ITGA2 KCNH3 TSPAN13 TTC39A PLCB4 UNC79	1.38e-07	193	135	8	6a9bce5064938b5b84ad57b4fd4a7841afe100c8
ToppCell	TCGA-Ovary-Primary_Tumor\|TCGA-Ovary / Sample_Type by Project: Shred V9	PKP4 KPNA6 PRAG1 CDC42BPB RHOBTB2 FAM20B	8.70e-07	106	135	6	14f548be39cec604fbdae0382cbf434fa4049840
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma\|TCGA-Ovary / Sample_Type by Project: Shred V9	PKP4 KPNA6 PRAG1 CDC42BPB RHOBTB2 FAM20B	8.70e-07	106	135	6	939b80950d39cdc7149a05fdfb64c8810064cdb1
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma\|TCGA-Ovary / Sample_Type by Project: Shred V9	PKP4 KPNA6 PRAG1 CDC42BPB RHOBTB2 FAM20B	8.70e-07	106	135	6	e9e1b55f32b3d5b9eeec94a997912e5c21c1fb48
ToppCell	droplet-Heart-nan-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DIP2B PDE2A CECR2 HSPA12B PIK3C2A TSPAN13 PLCB4	1.36e-06	181	135	7	92d44892bb15771f0ab5fe61879b204b0acbd9b3
ToppCell	COVID-19-Heart-EC_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL15A1 PKP4 CC2D2B TGM2 PIK3C2A PLCB4 OSMR	1.47e-06	183	135	7	ff95382cfed592190d0636d2b750328471f82e0d
ToppCell	LPS-IL1RA-Epithelial_alveolar\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SFTPB CECR2 ITGA2 PRSS36 TTC39A PLD5 MUC1	1.75e-06	188	135	7	6164d467b612767ceba15de34176bcc8e8c36ab8
ToppCell	E12.5-Epithelial-alveolar_epithelial_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SFTPB TMEM54 F2RL1 TSPAN13 TTC9 CTNND2 MUC1	1.75e-06	188	135	7	c19c89756f2f999e0814f08a89818ef156f6fc69
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	PTCHD4 CDC14A GASK1B ITPR1 PIK3C2A STRA6 UNC79	1.75e-06	188	135	7	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	COVID-19-Heart-EC_3\|Heart / Disease (COVID-19 only), tissue and cell type	PKP4 CC2D2B TGM2 CIITA PIK3C2A PLCB4 OSMR	1.88e-06	190	135	7	78e7c502b0450c0b37652b1896a2a752fd8a2111
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	DIP2B G2E3 ALG10B PIK3C2A PDS5A TRIM44 WDFY1	2.09e-06	193	135	7	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	SMG1 SESN3 CDC14A ITPR1 TMC8 ATM	1.02e-05	162	135	6	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	368C-Myeloid-Dendritic-pDC\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	COL15A1 G2E3 ZNF587B ZNF469 TSPAN13 TTC39A	1.38e-05	171	135	6	714a0b0d0c9886fef64170cf53eb64f0d8a47280
ToppCell	droplet-Lung-30m-Epithelial-alveolar_epithelial\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SFTPB TMEM54 CECR2 GJB6 TTC9 MUC1	1.74e-05	178	135	6	76e71fff99cf64302e2e3c0d66dd8ba0ff13624e
ToppCell	droplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SFTPB TMEM54 CECR2 GJB6 TTC9 MUC1	1.74e-05	178	135	6	82f78ea1ea3ff3e2347cd8bc2f06e2a10e96f220
ToppCell	droplet-Lung-30m-Epithelial\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SFTPB TMEM54 CECR2 GJB6 TTC9 MUC1	1.74e-05	178	135	6	5442bc52b8e902da1383f44d97a9f95e471a8d4d
ToppCell	droplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SFTPB TMEM54 CECR2 GJB6 TTC9 MUC1	1.74e-05	178	135	6	523b286ebe0359c7f1902f28cbd71f452626fc0d
ToppCell	droplet-Lung-LUNG-30m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFTPB TMEM54 CECR2 GJB6 TTC9 MUC1	1.91e-05	181	135	6	cadb18fc73031eb9f779599e15cd7861337fee78
ToppCell	droplet-Lung-LUNG-30m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFTPB TMEM54 CECR2 GJB6 TTC9 MUC1	1.91e-05	181	135	6	85bec4d3f255f4c61c790325eeb50ad38f709ef2
ToppCell	Control-Epithelial_alveolar-AT_1-AT1-AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SFTPB CECR2 F2RL1 PRSS36 PLD5 MUC1	1.97e-05	182	135	6	a95956ce4adccb34cc0c47ebfa1878ce4617904e
ToppCell	droplet-Heart-nan-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DIP2B CECR2 HSPA12B PIK3C2A TSPAN13 PLCB4	1.97e-05	182	135	6	81279877b920b5a1bc991a07d3031d6458700fe3
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SFTPB CECR2 ITGA2 PRSS36 PLD5 MUC1	2.09e-05	184	135	6	cdf6f1c6cce97a7effa0c55959652e2c0b6992b3
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	TRAF3 TRAF6 PKP4 ZBTB37 NUP155 GFPT2	2.16e-05	185	135	6	e06a784a297f357f3f8e761c24fa70722048ab42
ToppCell	E12.5-Epithelial\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SFTPB TMEM54 F2RL1 TSPAN13 CTNND2 MUC1	2.29e-05	187	135	6	29ea5e14dac3321df76f6aa4f053068b49c4a4bf
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A PKP4 HSPA12B TGM2 TSPAN13 PLCB4	2.36e-05	188	135	6	8a87daf2851d9404df7c36f279db599574b47c69
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A PKP4 HSPA12B TGM2 TSPAN13 PLCB4	2.36e-05	188	135	6	0f426cca2ad7671fed9c6d2aa09f6a8627a518cd
ToppCell	droplet-Lung-nan-18m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDC42BPA AQP11 TRPM5 RIPOR1 PLCB4 OSMR	2.36e-05	188	135	6	405efea75233ecf70f7d19b630230798d817b7f2
ToppCell	droplet-Limb_Muscle-nan-18m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A PKP4 HSPA12B TGM2 TSPAN13 RIPOR1	2.43e-05	189	135	6	a3f6ebd1622d36d114e42f6e0618d7b2fe8b9a2f
ToppCell	droplet-Limb_Muscle-nan-18m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A PKP4 HSPA12B TGM2 TSPAN13 RIPOR1	2.43e-05	189	135	6	d86455cf20769d70d62e2c1dd92cbc93c67aada5
ToppCell	10x5'v1-week_12-13-Mesenchymal_fibro-stroma-endosteal_fibroblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL15A1 TMEM54 NKAIN1 TTC9 GFPT2 MOCS1	2.43e-05	189	135	6	473b01c9162b12b90a617c600238436177a0d18d
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-large_intestine_goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A KCNH3 TSPAN13 TTC39A PLCB4 UNC79	2.43e-05	189	135	6	5a0fd34928117f162c83ca1b068aa8f7069a6765
ToppCell	droplet-Limb_Muscle-nan-18m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A PKP4 HSPA12B TGM2 TSPAN13 RIPOR1	2.43e-05	189	135	6	84036d1257f6b18f47cfc7ac5e6ed6ea3553c235
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B1\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	SHQ1 NUP155 SEC24C ALG10 TSPAN13 PIGM	2.51e-05	190	135	6	2434b8ad2976eab7d9147012c28454ab29670709
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CDC42BPA CTIF HSPA12B PLCB4 CTNND1 CTNND2	2.51e-05	190	135	6	474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PKP4 TGM2 CIITA PLCB4 CTNND1 CTNND2	2.58e-05	191	135	6	a7b18bcf27c38ad2353c239ecb309c80f3ef3359
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SHQ1 NUP155 SEC24C ALG10 TSPAN13 PIGM	2.58e-05	191	135	6	39ef8e1d7cc3ebb11717e8a55501515e3b72b177
ToppCell	facs-Heart-RV-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A PKP4 HSPA12B TGM2 TSPAN13 PLCB4	2.58e-05	191	135	6	84ebb9f8e975acc88aa600c08a8aa791256948a6
ToppCell	(7)_Epithelial-C_(AT2)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	SFTPB TMEM54 RHOBTB2 TSPAN13 TTC39A MUC1	2.74e-05	193	135	6	a3ca6ab20c8de260e410ddc14d3d202f28b9d6c2
ToppCell	LPS-antiTNF-Endothelial-Endothelial\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PKP4 CTIF HSPA12B PLCB4 CTNND1 CTNND2	2.74e-05	193	135	6	02f633b016ab19bfa65bfd0cf32f000549a62148
ToppCell	LPS-antiTNF-Endothelial\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PKP4 CTIF HSPA12B PLCB4 CTNND1 CTNND2	2.74e-05	193	135	6	5122b1ffba42de190061be34ecdc6176f84e56a3
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D231\|Adult / Lineage, Cell type, age group and donor	COL15A1 NTNG1 ITGA2 TGM2 GFPT2 MOCS1	2.74e-05	193	135	6	ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HSPA12B GASK1B CC2D2B TGM2 PLCB4 CMKLR1	2.74e-05	193	135	6	0b328f725f6feba263783eaca60c142e80df90f3
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL15A1 PKP4 CIITA RIPOR1 PLCB4 CTNND2	2.90e-05	195	135	6	56efeb58df19f357d7d5ce87348d4f196a595421
ToppCell	11.5-Airway-Epithelial-Secretory_progenitor\|Airway / Age, Tissue, Lineage and Cell class	SFTPB TMEM54 TBC1D2 TSPAN13 CTNND2 MUC1	2.90e-05	195	135	6	8cbc78a6cb812f907c69b00f85263976216840ac
ToppCell	COVID-19-Lymphoid-pDC\|Lymphoid / Condition, Lineage and Cell class	NLRP7 CIITA TSPAN13 TTC39A PLCB4 CMKLR1	2.90e-05	195	135	6	4a7c080230ce6a79335ecbeadecb0177b2c13625
ToppCell	AT2_cells-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	SFTPB ITGA2 GPR68 TSPAN13 OSMR MUC1	2.90e-05	195	135	6	bb45a17871a8a2593bc16a95f22e3c239c49985b
ToppCell	PBMC-Control-cDC_3\|Control / Compartment, Disease Groups and Clusters	KPNA6 ZNF469 CIITA CTNND1 DSE NOTCH2	2.98e-05	196	135	6	09d197b321ff9f13c0672ea059c850845b0dbbd5
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDE2A COL15A1 HSPA12B GASK1B CIITA CMKLR1	3.07e-05	197	135	6	cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCell	saliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CDC42BPA PKP4 F2RL1 LRRC42 TSPAN13 PLCB4	3.07e-05	197	135	6	d6c9da7a3a6d2bcb13e2fc6605c8a59e7fb121c5
ToppCell	(4)_Blood_vessel\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	PDE2A COL15A1 HSPA12B GASK1B TGM2 PLCB4	3.07e-05	197	135	6	1b82979a41ef46c814c82527a585900586d71260
ToppCell	saliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CDC42BPA PKP4 F2RL1 LRRC42 TSPAN13 PLCB4	3.07e-05	197	135	6	80b05c8ad9c1edc5dea3236079372475431343fe
ToppCell	(4)_Endothelial_cells\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	PDE2A COL15A1 HSPA12B GASK1B TGM2 PLCB4	3.07e-05	197	135	6	dd9abb43c23e7698433e455eacbf5b23b0a756c2
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDE2A COL15A1 HSPA12B GASK1B CIITA CMKLR1	3.07e-05	197	135	6	412cb5f37df57121ddd1492021445479c7cbccbf
ToppCell	Bronchial-10x5prime-Epithelial-Epi_alveolar-AT1\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SFTPB RBP2 AATK RHOBTB2 TSPAN13 MUC1	3.16e-05	198	135	6	54228dd9a50616d2022712d162a419ed0327cabd
ToppCell	10x3'2.3-week_17-19-Endothelial\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PDE2A COL15A1 ITGA2 HSPA12B GASK1B CTNND1	3.16e-05	198	135	6	2630a7a6e56febe5c0b0bde70dd7292fa1650c47
ToppCell	moderate-Epithelial-Secretory\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CDC42BPA TMEM54 TGM2 TSPAN13 CTNND1 MUC1	3.16e-05	198	135	6	7d96d7105a849c7280ce87bd76ce130ac47384fd
ToppCell	distal-Endothelial-Bronchial_Vessel_1-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PDE2A COL15A1 PKP4 HSPA12B GASK1B TSPAN13	3.16e-05	198	135	6	5bdffabf80716dd80c1265c3d126c7a25340251c
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PDE2A COL15A1 ITGA2 HSPA12B GASK1B CTNND1	3.16e-05	198	135	6	1e83bec16dcd60460422625f89952ff506d6be51
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-AT1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SFTPB RBP2 RHOBTB2 TSPAN13 PLD5 MUC1	3.25e-05	199	135	6	f8846446ebbc4948cdc69640782db1358bbdc486
ToppCell	Biopsy_IPF-Epithelial-Transitional_AT2\|Biopsy_IPF / Sample group, Lineage and Cell type	SFTPB RBP2 AATK RHOBTB2 TSPAN13 MUC1	3.25e-05	199	135	6	83ff8b7e472d1212324c05cc719b746d19e5e23b
ToppCell	Parenchyma_COVID-19-Epithelial-TX-AT1\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	SFTPB RBP2 RHOBTB2 TSPAN13 PLD5 MUC1	3.25e-05	199	135	6	fe9f5bc317be0c35bd96311bf0b3c7b91d98acc5
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	DIP2B VPS54 NBAS PLCB4 RAPGEF2 FTO	3.25e-05	199	135	6	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDE2A COL15A1 PKP4 ITGA2 HSPA12B GASK1B	3.25e-05	199	135	6	f0bf75bfae7b288ecb6801be458b03ebd0108ea7
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-AT1\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SFTPB RBP2 RHOBTB2 TSPAN13 PLD5 MUC1	3.25e-05	199	135	6	3e35ee426ef06f9af568c37349b62dd1ee9b97ea
ToppCell	metastatic_Lymph_Node-Epithelial_cells-Malignant_cells\|metastatic_Lymph_Node / Location, Cell class and cell subclass	SFTPB TMEM54 TGM2 TSPAN13 OSMR MUC1	3.34e-05	200	135	6	5e2def2e56f21bc7295cdcf3580f5c0d16a6a494
ToppCell	Parenchyma_COVID-19-Epithelial-TX-Transitional_AT2\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	SFTPB TMEM54 RHOBTB2 TSPAN13 PLD5 MUC1	3.34e-05	200	135	6	dfa897ef5ce4744c77b6e5ee5a0d6d83229d1691
ToppCell	Neuronal-Excitatory-eH(THEMIS)-CRABP1-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	NTNG1 ATP10A CDC14A GASK1B NWD2 PLD5	3.34e-05	200	135	6	473e85930f433e392956a7a10ea5d09fdc2a35b1
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Vein\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PKP4 HSPA12B TGM2 TSPAN13 PLCB4 CMKLR1	3.34e-05	200	135	6	b3f93b71589251197cde96b7bc6d065c106f61cd
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Transitional_AT2-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SFTPB TMEM54 RHOBTB2 TSPAN13 PLD5 MUC1	3.34e-05	200	135	6	8d1c78dd829cbc290820d5118f24ff7f828a8622
ToppCell	metastatic_Lymph_Node-Epithelial_cells\|metastatic_Lymph_Node / Location, Cell class and cell subclass	SFTPB TMEM54 TGM2 TSPAN13 OSMR MUC1	3.34e-05	200	135	6	07408011b37d32a20164866cf5da9dd120985357
ToppCell	Neuronal-Excitatory-eH(THEMIS)-CRABP1--\|Neuronal / cells hierarchy compared to all cells using T-Statistic	NTNG1 ATP10A CDC14A GASK1B NWD2 PLD5	3.34e-05	200	135	6	73b7e395398fdc9aa5adb3ade675ae0168d7f46c
ToppCell	Neuronal-Excitatory-eH(THEMIS)-CRABP1---L5-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	NTNG1 ATP10A CDC14A GASK1B NWD2 PLD5	3.34e-05	200	135	6	c9113e7a9624499db3e66c01462159e8e8781cc4
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDE2A COL15A1 PKP4 ITGA2 HSPA12B GASK1B	3.34e-05	200	135	6	90061284a80d29a4ca6078f578e13d32b8cc80e1
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Transitional_AT2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SFTPB TMEM54 RHOBTB2 TSPAN13 PLD5 MUC1	3.34e-05	200	135	6	992bd6b1feac2afded6eb927ac95ddf5cfef961c
ToppCell	Neuronal-Excitatory-eH(THEMIS)-CRABP1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	NTNG1 ATP10A CDC14A GASK1B NWD2 PLD5	3.34e-05	200	135	6	a737c4f535723e389ba4b957ae1fdc5162d3d951
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SFTPB PTCHD4 RXFP4 PLD5 CMKLR1	5.53e-05	134	135	5	64979e1a056b7406e1be39c5ebe2f8d731ac3c17
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE2A COL15A1 PLEKHF1 SHISA4 TSPAN13	7.78e-05	144	135	5	f501e11b1d051ca67124137017a79a2d5bb6ae87
ToppCell	PND28-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SFTPB TMEM54 GJB6 NWD2 MUC1	8.03e-05	145	135	5	9b69bfdbf91ef197b4c483617aa67498d9d2cd79
ToppCell	PND28-Epithelial-Epithelial_Airway-Neurosecretory-Secretory\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SFTPB TMEM54 GJB6 NWD2 MUC1	8.03e-05	145	135	5	31af9fce1dcd7e8ae1604476598e099232017ee9
ToppCell	PND28-Epithelial-Epithelial_Airway-Neurosecretory\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SFTPB TMEM54 GJB6 NWD2 MUC1	8.03e-05	145	135	5	76f0cde9acdc3ad5948c007dccf312665972c9e6
ToppCell	normal_Lymph_Node-Myeloid_cells-CD163+CD14+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	FHIP1B CC2D2B CASD1 ATM PIGM	9.13e-05	149	135	5	a34d095b8e0fe59d69d84e4fd2fe4ccb82f92e4f
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	F2RL1 CDC42BPB ALG10 ZBTB21 RIPOR1	1.00e-04	152	135	5	b8aa62e3cf2b4c252db4bccfa75d881c4fa0a788
ToppCell	P28-Epithelial-epithelial_progenitor_cell-epi_progenitor\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SFTPB GJB6 F2RL1 TTC9 MUC1	1.10e-04	155	135	5	be575a0096415705dba425002247289ff8f89474
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_1-Tnr-Polydendrocyte.Tnr.Opalin_(Opalin)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	IQCH ITGA2 DCST1 TRPM5	1.13e-04	82	135	4	5cd8e47edb775eabf3e9a407c1c2d8a78afb9509
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_1-Tnr\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	IQCH ITGA2 DCST1 TRPM5	1.13e-04	82	135	4	1eeb259ec555879ee1962b7bc2c31c200fbb85cf
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NTNG1 ATP10A CDC14A KCNH3 RIPOR1	1.24e-04	159	135	5	fd7db2f7328cfefdc3ada2af91006d5a91d137e1
ToppCell	Severe-B_naive-1\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	PRAG1 ITPR1 CIITA RIPOR1 NOTCH2	1.24e-04	159	135	5	2881b054bbeb479221ee3c38bbd9b0815b123579
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NTNG1 ATP10A CDC14A KCNH3 RIPOR1	1.24e-04	159	135	5	aaf449c768d6fbb0a1bb47746ff3bdb7f9eb8914
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NTNG1 ATP10A CDC14A KCNH3 RIPOR1	1.24e-04	159	135	5	8bbdef1e927f3130b578d7d7c5ff38bbe06fab63
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B1\|367C / Donor, Lineage, Cell class and subclass (all cells)	SHQ1 NUP155 SEC24C ALG10 PIGM	1.31e-04	161	135	5	f470b662566131dfe69a2fd01186ac8491196396
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE2A COL15A1 HSPA12B GASK1B ZNF469	1.35e-04	162	135	5	c399b9e4854916a59f5cae2d8dbf19660f8759be
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE2A COL15A1 HSPA12B GASK1B ZNF469	1.35e-04	162	135	5	a291248b693c771845174393934a782f1d8bd7ce
ToppCell	368C-Myeloid-Dendritic-pDC\|368C / Donor, Lineage, Cell class and subclass (all cells)	G2E3 ZNF587B ZNF469 TSPAN13 TTC39A	1.56e-04	167	135	5	1e2fc1637769405a61f4c7e44945712a1888a299
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells-neuroepithelial-like_cells\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	LZTR1 CDC14A PRSS36 ULK4 UNC79	1.56e-04	167	135	5	e488d9c7cf4355959e3833de3bd496c13fc11b1b
ToppCell	CV-Mild-6\|CV / Virus stimulation, Condition and Cluster	FAM120B PRSS36 XPNPEP3 TMC8 CTNND1	1.56e-04	167	135	5	cf2ed0b6d17a16f9a2318879ce8856d5983ad3cf
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM54 DZIP1L KCNH3 CMKLR1 MUC1	1.69e-04	170	135	5	a121e10099faaeb60251eec162f38caf7c4238c2
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PDE2A COL15A1 PKP4 GASK1B CC2D2B	1.69e-04	170	135	5	1a568efcff9c39b3f709b55a05d24710450a2657
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PDE2A COL15A1 PKP4 GASK1B CC2D2B	1.69e-04	170	135	5	66d41d794790e621d72ac37af995510537103c9c
ToppCell	Children_(3_yrs)-Immune-B_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ZNF821 TRAF3 SESN3 ITPR1 TMC8	1.69e-04	170	135	5	e421f9eedf74baffda1d03707a710ece4b777f29
ToppCell	368C-Myeloid-Dendritic-pDC\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	COL15A1 ZNF587B ZNF469 TSPAN13 TTC39A	1.74e-04	171	135	5	f3bf5805823d5733b58742172e7668725ce82931
Drug	Isoxicam [34552-84-6]; Down 200; 12uM; MCF7; HT_HG-U133A	ZNF821 SFTPB PKP4 KPNA6 CDC42BPB RIPOR1 ATM CTNND2 CABIN1	2.45e-06	197	133	9	1698_DN
Drug	Methionine sulfoximine (L) [15985-39-4]; Up 200; 22.2uM; MCF7; HT_HG-U133A	LZTR1 SFTPB ITPR1 USP2 RHOBTB2 ATM STRA6 VPS53	1.76e-05	192	133	8	2831_UP
Drug	Pramoxine hydrochloride [637-58-1]; Up 200; 12.2uM; MCF7; HT_HG-U133A	PDE2A CDC42BPA PLEKHF1 CTIF CDC14A ITPR1 USP2 TTC39A	1.97e-05	195	133	8	4368_UP
Drug	5162773; Down 200; 7uM; MCF7; HT_HG-U133A_EA	RHOBTB2 RIPOR1 TTC9 ATM OSMR ANKRD40 DSE HTT	2.04e-05	196	133	8	892_DN
Drug	NS-398; Down 200; 10uM; MCF7; HT_HG-U133A	FLII ITGA2 KLHDC3 FAM20B CABIN1 MUC1 MOCS1 NOTCH2	2.12e-05	197	133	8	6911_DN
Drug	Kynurenine, 3-hydroxy (R,S) [2147-61-7]; Down 200; 17.8uM; PC3; HT_HG-U133A	SFTPB CTIF AATK TTC39A CHRNA10 RAPGEF2 NOTCH2 DOP1A	2.20e-05	198	133	8	4681_DN
Drug	Isocarboxazid [59-63-2]; Down 200; 17.2uM; HL60; HT_HG-U133A	LZTR1 CTIF CDC14A DIP2A GPR68 TSPAN13 MUC1 NOTCH2	2.28e-05	199	133	8	2562_DN
Drug	Spiramycin [8025-81-8]; Up 200; 4.8uM; PC3; HT_HG-U133A	ZNF821 PDE2A SFTPB PKP4 ATP10A NKAIN1 STRA6 CHRNA10	2.28e-05	199	133	8	3762_UP
Drug	Monobenzone [103-16-2]; Up 200; 20uM; PC3; HT_HG-U133A	ZNF821 PKP4 TBC1D2 NTNG1 CTIF GASK1B AFM CTNND2	2.28e-05	199	133	8	6713_UP
Disease	Long Qt Syndrome 2	ALG10B ALG10	5.76e-05	3	130	2	C3150943
Disease	Warsaw breakage syndrome (implicated_via_orthology)	DDX11 DDX11L8	5.76e-05	3	130	2	DOID:0060535 (implicated_via_orthology)
Disease	response to peginterferon alfa-2a	IQCH ATP10A NBAS	1.79e-04	25	130	3	EFO_0010103
Disease	nonsyndromic deafness (implicated_via_orthology)	ALG10B ALG10	2.86e-04	6	130	2	DOID:0050563 (implicated_via_orthology)
Disease	body fat percentage	PDS5B TRAF3 IQCH NTNG1 RNH1 ULK4 FTO UNC79 HTT	3.24e-04	488	130	9	EFO_0007800
Disease	Glioblastoma	LZTR1 TGM2 CTNND2 NOTCH2	4.19e-04	79	130	4	C0017636
Disease	Giant Cell Glioblastoma	LZTR1 TGM2 CTNND2 NOTCH2	5.28e-04	84	130	4	C0334588
Disease	Inherited neuropathies	ITPR1 COQ8A ATM	7.33e-04	40	130	3	C0598589
Disease	cerebral cavernous malformation (implicated_via_orthology)	CDC42BPA CDC42BPB	1.03e-03	11	130	2	DOID:0060669 (implicated_via_orthology)
Disease	Glioblastoma Multiforme	LZTR1 TGM2 CTNND2 NOTCH2	1.50e-03	111	130	4	C1621958
Disease	diffuse large B-cell lymphoma	CDC42BPB EXOC2	1.69e-03	14	130	2	EFO_0000403
Disease	Neoplasm of uncertain or unknown behavior of bladder	ATM NOTCH2	1.95e-03	15	130	2	C0496930
Disease	Benign neoplasm of bladder	ATM NOTCH2	1.95e-03	15	130	2	C0154017
Disease	Carcinoma in situ of bladder	ATM NOTCH2	1.95e-03	15	130	2	C0154091
Disease	Gastro-enteropancreatic neuroendocrine tumor	CIITA NOTCH2	1.95e-03	15	130	2	C2930967
Disease	2-hydroxyglutarate measurement	PLD5 D2HGDH	2.22e-03	16	130	2	EFO_0021506
Disease	serum gamma-glutamyl transferase measurement	TRAF3 CDC42BPA IQCH SFTPB NTNG1 HSPA12B CDC42BPB ITPR1 CABIN1 G6PC1 NOTCH2	2.43e-03	914	130	11	EFO_0004532
Disease	sphingosine 1-phosphate measurement	ITPR1 FTO	2.81e-03	18	130	2	EFO_0800185
Disease	Carcinoma of bladder	ATM NOTCH2	2.81e-03	18	130	2	C0699885
Disease	type 2 diabetes mellitus (is_marker_for)	ITGA2 PIK3C2A FTO G6PC1	3.13e-03	136	130	4	DOID:9352 (is_marker_for)
Disease	common carotid intimal medial thickness	SESN3 PRAG1 CTNND2	3.26e-03	67	130	3	EFO_0004860
Disease	sarcopenia	TTC9 FTO	3.47e-03	20	130	2	EFO_1000653
Disease	unipolar depression, bipolar disorder, schizophrenia	METTL9 FTO	3.47e-03	20	130	2	EFO_0003761, MONDO_0004985, MONDO_0005090
Disease	corneal hysteresis	ZNF469 ANAPC1	3.47e-03	20	130	2	EFO_0010066
Disease	Infiltrating duct carcinoma of female breast	SMG1 CDC42BPB	3.83e-03	21	130	2	C3165106
Disease	opioid dependence	GJB6 NWD2 RIPOR1 CTNND2 FTO	4.07e-03	237	130	5	EFO_0005611
Disease	lung disease (is_marker_for)	SFTPB MUC1	4.20e-03	22	130	2	DOID:850 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
NCVCTLRNLSYRLEL	PKP4	741	Q99569
AAAYVCNLLLPCVLI	CHRNA10	236	Q9GZZ6
CPIYTCLRELLQSQD	CTIF	501	O43310
LRIVQIYKDLLRNCC	AFM	371	P43652
LLRLSLYNNCICDVG	CIITA	1046	P33076
NCTYNLTILDCLQGI	CDC14A	136	Q9UNH5
CCLEYVQQFLTRLIN	DOP1A	676	Q5JWR5
RLVCELSCYAIVNFI	ALG10B	436	Q5I7T1
ELTYQELLRVCCCEL	ANKRD40	286	Q6AI12
LCARLLQLYECFQDR	CC2D2B	311	Q6DHV5
ISDLIACLLQGCYQR	CECR2	56	Q9BXF3
VENCVCILRNLSYRL	CTNND2	761	Q9UQB3
LLDQCLCYVQSRGLQ	ATP10A	926	O60312
LLLSVCEQLAVNYRC	NWD2	466	Q9ULI1
LCALAINDECYQVRQ	PDS5B	906	Q9NTI5
ILDRCSYQICVIANN	OSMR	496	Q99650
LCALVINDECYQVRQ	PDS5A	916	Q29RF7
LCDILDANVNVIYIC	IQCH	481	Q86VS3
DVKGLTYCVLQCLQL	KCNH3	661	Q9ULD8
FLCFLVESQLQLRCV	ANAPC1	441	Q9H1A4
QLIIEYLLHCQDCLS	DZIP1L	91	Q8IYY4
NLSCEDVLLQLVLRY	FHIP1B	411	Q8N612
CIQLTNDYLCVCRSA	NOTCH2	1281	Q04721
CRDYVLNCSILNPLL	KPNA6	201	O60684
LFLCQLSAIELCYTL	OR10AC1	61	Q8NH08
LQSLLDTRCVYILDC	FLII	766	Q13045
SFQLCRLEQLCRQYI	LZTR1	556	Q8N653
ILNVRLDYRISCLLC	ITPR1	991	Q14643
CSTGTLDYILQRCQL	FTO	326	Q9C0B1
VYLIALAVCQCRRKN	MUC1	1176	P15941
TSEQRLLIVLSNCCY	EXOC2	706	Q96KP1
LFVDLCCQAYNLIRK	PIK3C2A	1311	O00443
QYLQQETRASRCCLL	PDE2A	251	O00408
VNALCRAIKLQCELY	DIP2B	1176	Q9P265
QCELYSSRQIAICLD	DIP2B	1186	Q9P265
CIQSLRSQLQLYLTC	KIF24	1341	Q5T7B8
FQYDVISCLNLLDRC	METTL9	201	Q9H1A3
GQRCLYAVLLIDSCI	DSE	931	Q9UL01
CSLCLRNRYLVISEK	LRRC42	151	Q9Y546
VQCLAVLRDRLCVGY	CDC42BPB	1376	Q9Y5S2
EQVLLAYSRCIQACG	DDX11	746	Q96FC9
QRRVLINLYCCAAED	HSPA12B	601	Q96MM6
VLALSQGILNCCLAY	ITGA2	16	P17301
LECIYTCERNDQLCL	NBAS	996	A2RRP1
TCERNDQLCLCYDLL	NBAS	1001	A2RRP1
YNALCKTLQRDCLVL	PIP5K1A	301	Q99755
IQTRLAYVCCVRQLE	PNPLA7	1146	Q6ZV29
YLRISLTEKCNLRCQ	MOCS1	71	Q9NZB8
ALIASLINCYIRDNA	NUP155	836	O75694
VELRLLGEATCQCLY	PRSS36	196	Q5K4E3
ILTQRICDCLYQGIL	PRSS36	731	Q5K4E3
YIVALCLSTLNSCID	F2RL1	326	P55085
ENCGCVYQLRVRLLD	FBXO17	191	Q96EF6
LFRCGQACLLLTEYQ	FKBP6	256	O75344
DFLLQIYNRLDTNCC	GASK1B	371	Q6UWH4
ECYNYLELIGCLRLI	G2E3	516	Q7L622
RFLCKAVENYINCLL	ATM	2461	Q13315
VRGLNQDCCVVYRLI	ARAF	51	P10398
RGALILFCDYVCQNL	HTT	1896	P42858
CQVLFRLNFLVVVLC	CASD1	491	Q96PB1
QFLTEQCIASFRLCL	CABIN1	1506	Q9Y6J0
ILYRTCTLENVKNIC	GFPT2	221	O94808
LVLLYELKQACANCE	DMAP1	371	Q9NPF5
LRCSYVVNQAILSCR	DCST1	246	Q5T197
AVQLNVCLSRIYLAA	G6PC1	161	P35575
NVAELCYLLLKVCFR	GJB6	206	O95452
VEQVLLAYSRCIQAC	DDX11L8	746	A8MPP1
QEIRNEICYNILVLC	COQ8A	461	Q8NI60
EICYNILVLCLRELF	COQ8A	466	Q8NI60
ICQRCNELRYLSDIL	MCF2	296	P10911
LCKLAVIQYNLDQSC	KLHDC3	341	Q9BQ90
VCLFCLLLVYRCTQQ	HERVK_113	646	Q902F9
LQCELYPSRQIAICL	DIP2A	1181	Q14689
AYSCANRLIVLCIEN	COL15A1	1366	P39059
LLQCALLYTSCAGQR	SEC24C	806	P53992
NLALNCCTQLADLYR	SEC24C	826	P53992
LITQCAQILACYRKN	SEC24C	871	P53992
VENCVCLLRNLSYQV	CTNND1	576	O60716
ISRVLATNVYLRCCL	DPY19L2P2	326	Q6ZN68
LVCQAGCVLEELSRY	D2HGDH	166	Q8N465
CCLLIYLFVQVDTLC	FAM120B	721	Q96EK7
LQLTQTLGLECCLLY	PBOV1	111	Q9GZY1
TCGLLECNQREVILY	KBTBD12	61	Q3ZCT8
DLSCQVCGILLYENI	GPR68	91	Q15743
NRCSYIDLLNTVICV	NTNG1	371	Q9Y2I2
VRVCSLCYRELAAQQ	PLEKHF1	201	Q96S99
NSCLNPVLYCLVRRE	RXFP3	381	Q9NSD7
NSCLNPVLYCLLRRE	RXFP4	301	Q8TDU9
SRIIEYCRNDNKLLC	TRIM42	296	Q8IWZ5
LSTYCQEDRQLICVL	TRIM44	186	Q96DX7
YRQVLLAGCRCVELD	PLCB4	346	Q15147
VIFYNCSCLVLDLQR	PLD5	251	Q8N7P1
CSCLVLDLQRIFALY	PLD5	256	Q8N7P1
CQCLAERYSVILLDT	SFTPB	246	P07988
LQCLAQCAEVTPYLL	AATK	186	Q6ZMQ8
DCISILCLIYTLNFA	PTCHD4	711	Q6ZW05
YVRQSICNLLCRVAQ	SMG1	1836	Q96Q15
ICARACNATLTQYQL	RHOBTB2	31	Q9BYZ6
CLSPLVCRLSLRQYQ	SPPL2C	296	Q8IUH8
RACRQVCYSLIDILL	SHQ1	266	Q6PI26
YCCRDLTLLITERQQ	SHISA4	61	Q96DD7
VLQQCSITKLGCRYL	NLRP7	881	Q8WX94
VAFCCLQLVAALERQ	NKAIN1	11	Q4KMZ8
LLDILICLYDECNNS	CDC42BPA	31	Q5VT25
QGNCYLAALNCLRLI	NUP160	1121	Q12769
LYLELTCGDQVCRQV	RBP2	116	P50120
ALEVCYISALVLSCL	STRA6	361	Q9BX79
RLICELSCYAVVNFI	ALG10	436	Q5BKT4
LLAQLVSALCSRYCT	AQP11	121	Q8NBQ7
ITACYLTIVCKLQRN	CMKLR1	236	Q99788
TNNTAEEYVCRLLLC	TGM2	496	P21980
CQFVCIAQQDYCRIL	RAPGEF2	221	Q9Y4G8
CKREILALQIYCRNE	TRAF3	106	Q13114
LALQIYCRNESRGCA	TRAF3	111	Q13114
VYQCRLCNAKLSSLL	ZBTB21	721	Q9ULJ3
QTACRLLSYLRVNVL	TMC8	291	Q8IU68
EQLLSFCYTGRICLQ	ZBTB37	81	Q5TC79
LCVAENVFAVRCAQL	TMEM54	166	Q969K7
NCLCALNLLYTLVSL	TSPAN13	11	O95857
RIKCLESQINYCSVL	TRPM5	1101	Q9NZQ8
AANYLLCTNCRKVLR	SESN3	11	P58005
ANVICEYCNTILIRE	TRAF6	211	Q9Y4K3
ERSILAPLYQCCIIR	FAM20B	321	O75063
CLRSQRLKLCLDYVN	TTC41P	86	Q6P2S7
QCRLEKLQLEYCSLS	RNH1	141	P13489
EAYERRVCFLLLQLC	PRAG1	1116	Q86YV5
LICNILSTAEYCLAT	VPS53	551	Q5VIR6
QLDVLLTCRQCDRNY	ZNF469	726	Q96JG9
QRCLYRDVTLENLAL	ZNF587B	36	E7ETH6
YEAVLEIQRDCLALC	XPNPEP3	361	Q9NQH7
LVCNNCAAYRKLLEA	ZNF821	236	O75541
ILQCLSNTRELRDYC	USP2	281	O75604
LCPVERVLLTFCNQY	RIPOR1	986	Q6ZS17
FQACLYELLKRLCNR	PIGM	211	Q9H3S5
VCYAECLLQRAALTF	TTC39A	126	Q5SRH9
QSLCYLQLTRQLVSC	WDFY1	246	Q8IWB7
ALLTKCAYLQARNCQ	TBC1D2	491	Q9BYX2
QRCLYRDVTLENLAL	ZNF814	36	B7Z6K7
INSAAILLYALTCCI	TM9SF1	341	O15321
ASRAKLNLLCYLCVV	ULK4	481	Q96C45
LLLIRIILEYCQCVD	VPS54	746	Q9P1Q0
IEIDCYNSLAACLLQ	TTC9	126	Q92623
IECNLCQSSILCYQL	UNC79	856	Q9P2D8
ILECLNEQRLQGLYC	NACC1	16	Q96RE7