Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal protein binding

CACNA1D SETD2 BRCA1 BRCA2 MYO5A CFL1 CEP70 KIF14 PSTPIP2 NEB MAP3K1 MYO5C

7.36e-0510995912GO:0008092
GeneOntologyBiologicalProcesscytokinesis

USP8 SETD2 BRCA2 CFL1 KIF14 EXOC1

1.87e-05204566GO:0000910
GeneOntologyBiologicalProcesschromatin organization

RAG1 RIF1 SETD2 PBRM1 BRCA1 LMNA BRCA2 BAZ2B SYCP1 PHF14 ZNF445

2.42e-058965611GO:0006325
GeneOntologyBiologicalProcessprotein-DNA complex organization

RAG1 RIF1 SETD2 PBRM1 BRCA1 LMNA BRCA2 BAZ2B SYCP1 PHF14 ZNF445

6.53e-059995611GO:0071824
GeneOntologyCellularComponentlateral element

BRCA1 BRCA2 SYCP1

1.81e-0519573GO:0000800
GeneOntologyCellularComponentneuron spine

USP8 ADRB2 ABR CFL1 EEA1 EPHA4

5.61e-05247576GO:0044309
GeneOntologyCellularComponentSchaffer collateral - CA1 synapse

ADRB2 ABR MYO5A EEA1 EPHA4

6.45e-05155575GO:0098685
GeneOntologyCellularComponentsynaptonemal complex

BRCA1 BRCA2 SYCP1

2.68e-0446573GO:0000795
GeneOntologyCellularComponentsynaptonemal structure

BRCA1 BRCA2 SYCP1

2.68e-0446573GO:0099086
GeneOntologyCellularComponentdendritic spine

USP8 ADRB2 ABR CFL1 EPHA4

5.12e-04242575GO:0043197
GeneOntologyCellularComponentchromosome, telomeric repeat region

RIF1 ACD

6.51e-0414572GO:0140445
GeneOntologyCellularComponentcondensed chromosome

RIF1 PBRM1 BRCA1 BRCA2 SYCP1

1.48e-03307575GO:0000793
GeneOntologyCellularComponentDNA repair complex

BRCA1 BRCA2

1.78e-0323572GO:1990391
GeneOntologyCellularComponentearly endosome

PI4K2B USP8 ADRB2 MYO5A EEA1 EPHA4

1.93e-03481576GO:0005769
GeneOntologyCellularComponentcondensed nuclear chromosome

BRCA1 BRCA2 SYCP1

1.97e-0391573GO:0000794
HumanPhenoAcholic stools

BRCA1 BRCA2 ROS1

4.99e-069213HP:0011985
HumanPhenoBiliary tract neoplasm

BRCA1 BRCA2 ROS1

3.27e-0516213HP:0100574
MousePhenoabnormal skin pigmentation

RAG1 BRCA1 LMNA ACD MYO5A

7.46e-0687445MP:0002095
MousePhenoabnormal epidermal melanocyte morphology

LMNA MYO5A

5.79e-054442MP:0009388
MousePhenoabnormal double-strand DNA break repair

RIF1 BRCA1 LMNA BRCA2

6.73e-0570444MP:0010948
MousePhenohairpin sperm flagellum

TTC29 ROS1 CEP128

1.00e-0429443MP:0009243
DomainZnf_C2H2-like

RAG1 ZNF594 ZFHX4 ZNF451 ZNF184 ZNF790 ZBTB21 ZFHX3 EEA1 ZNF782 ZNF445

2.86e-057965811IPR015880
DomainZnF_C2H2

RAG1 ZNF594 ZFHX4 ZNF451 ZNF184 ZNF790 ZBTB21 ZFHX3 EEA1 ZNF782 ZNF445

3.28e-058085811SM00355
Domain-

RAG1 RC3H2 BRCA1 BAZ2B PHF14 EEA1 OBI1 MAP3K1

7.00e-054495883.30.40.10
DomainZnf_RING/FYVE/PHD

RAG1 RC3H2 BRCA1 BAZ2B PHF14 EEA1 OBI1 MAP3K1

8.17e-05459588IPR013083
DomainMyosin_S1_N

MYO5A MYO5C

9.42e-055582IPR008989
DomainZINC_FINGER_C2H2_2

ZNF594 ZFHX4 ZNF451 ZNF184 ZNF790 ZBTB21 ZFHX3 EEA1 ZNF782 ZNF445

1.22e-047755810PS50157
DomainZINC_FINGER_C2H2_1

ZNF594 ZFHX4 ZNF451 ZNF184 ZNF790 ZBTB21 ZFHX3 EEA1 ZNF782 ZNF445

1.25e-047775810PS00028
DomainDIL

MYO5A MYO5C

1.41e-046582PF01843
DomainDilute_dom

MYO5A MYO5C

1.41e-046582IPR002710
DomainDILUTE

MYO5A MYO5C

1.41e-046582PS51126
DomainDIL

MYO5A MYO5C

1.41e-046582SM01132
DomainZnf_C2H2

ZNF594 ZFHX4 ZNF451 ZNF184 ZNF790 ZBTB21 ZFHX3 EEA1 ZNF782 ZNF445

1.67e-048055810IPR007087
Domain-

RAG1 ZNF594 ZFHX4 ZNF184 ZNF790 ZBTB21 ZFHX3 ZNF782 ZNF445

2.27e-046795893.30.160.60
Domainzf-C2H2

ZNF594 ZFHX4 ZNF451 ZNF184 ZNF790 ZBTB21 ZFHX3 ZNF782 ZNF445

2.65e-04693589PF00096
DomainZnf_C2H2/integrase_DNA-bd

RAG1 ZNF594 ZFHX4 ZNF184 ZNF790 ZBTB21 ZFHX3 ZNF782 ZNF445

2.67e-04694589IPR013087
DomainIQ

MYO5A SCN7A MYO5C

2.04e-0381583SM00015
DomainZF_RING_1

RAG1 RC3H2 BRCA1 OBI1 MAP3K1

2.07e-03291585PS00518
DomainZF_RING_2

RAG1 RC3H2 BRCA1 OBI1 MAP3K1

2.30e-03298585PS50089
DomainRING

RAG1 RC3H2 BRCA1 OBI1 MAP3K1

2.54e-03305585SM00184
DomainIQ_motif_EF-hand-BS

MYO5A SCN7A MYO5C

2.76e-0390583IPR000048
DomainBromodomain_CS

PBRM1 BAZ2B

2.94e-0326582IPR018359
DomainZnf_RING

RAG1 RC3H2 BRCA1 OBI1 MAP3K1

3.38e-03326585IPR001841
DomainZnF_U1

ZFHX4 ZFHX3

3.65e-0329582SM00451
DomainZnf_U1

ZFHX4 ZFHX3

3.65e-0329582IPR003604
DomainIon_trans_dom

CACNA1D SCN7A ITPR2

5.35e-03114583IPR005821
DomainIon_trans

CACNA1D SCN7A ITPR2

5.35e-03114583PF00520
DomainBROMODOMAIN_1

PBRM1 BAZ2B

5.89e-0337582PS00633
DomainMyosin_head_motor_dom

MYO5A MYO5C

6.20e-0338582IPR001609
DomainBromodomain

PBRM1 BAZ2B

6.20e-0338582PF00439
DomainMYOSIN_MOTOR

MYO5A MYO5C

6.20e-0338582PS51456
DomainMyosin_head

MYO5A MYO5C

6.20e-0338582PF00063
DomainMYSc

MYO5A MYO5C

6.20e-0338582SM00242
Domain-

RC3H2 ZC3H6

6.85e-03405824.10.1000.10
DomainBROMODOMAIN_2

PBRM1 BAZ2B

7.19e-0341582PS50014
DomainBROMO

PBRM1 BAZ2B

7.54e-0342582SM00297
DomainBromodomain

PBRM1 BAZ2B

7.54e-0342582IPR001487
Domain-

PBRM1 BAZ2B

7.54e-03425821.20.920.10
PathwayREACTOME_MEIOSIS

BRCA1 LMNA ACD BRCA2 SYCP1

2.41e-05120415M529
PathwayREACTOME_MEIOTIC_SYNAPSIS

BRCA1 LMNA ACD SYCP1

7.52e-0578414M1061
PathwayREACTOME_REPRODUCTION

BRCA1 LMNA ACD BRCA2 SYCP1

8.98e-05158415M26956
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

USP8 PDE6A BRCA1 LMNA MYO5A CFL1 ZBTB21 SYCP1 PHF14 EEA1 NEB KRT79 CEP128 OBI1 HSPA6 GOLGB1 ESF1 EPHA4

2.08e-111442601835575683
Pubmed

Association between mitogen-activated protein kinase kinase kinase 1 rs889312 polymorphism and breast cancer risk: evidence from 59,977 subjects.

BRCA1 BRCA2 MAP3K1

4.88e-09360320809358
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

ZFHX4 BRCA2 ZBTB21 KIF14 ZFHX3 ICE1 OBI1 HSPA6 GOLGB1

4.13e-0841860934709266
Pubmed

Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers.

BRCA1 BRCA2 MAP3K1

4.87e-08560318355772
Pubmed

Longitudinal profiling identifies co-occurring BRCA1/2 reversions, TP53BP1, RIF1 and PAXIP1 mutations in PARP inhibitor-resistant advanced breast cancer.

RIF1 BRCA1 BRCA2

4.87e-08560338244928
Pubmed

Breast cancer susceptibility variants alter risks in familial disease.

BRCA1 BRCA2 MAP3K1

9.73e-08660319617217
Pubmed

Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions.

SETD2 PBRM1 BRCA1 BRCA2 MAP3K1

1.54e-077160528319113
Pubmed

Exome sequencing identifies breast cancer susceptibility genes and defines the contribution of coding variants to breast cancer risk.

BRCA1 BRCA2 MAP3K1

5.81e-071060337592023
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

RIF1 SETD2 BRCA1 LMNA BRCA2 BAZ2B CFL1 ZNF451 PHF14 ICE1 ESF1

6.27e-07954601136373674
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

RIF1 PBRM1 LMNA MYO5A CFL1 ZBTB21 KIF14 EEA1 GOLGB1 MYO5C ITPR2

1.25e-061024601124711643
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

BRCA1 BRCA2 BAZ2B ZNF451 ZBTB21 ESF1

2.37e-0622260637071664
Pubmed

Association of BRCA1/2 mutations with ovarian cancer prognosis: An updated meta-analysis.

BRCA1 BRCA2

2.93e-06260229480828
Pubmed

A systematic genetic assessment of 1,433 sequence variants of unknown clinical significance in the BRCA1 and BRCA2 breast cancer-predisposition genes.

BRCA1 BRCA2

2.93e-06260217924331
Pubmed

Attitudes, knowledge, risk perceptions and decision-making among women with breast and/or ovarian cancer considering testing for BRCA1 and BRCA2 and their spouses.

BRCA1 BRCA2

2.93e-06260212833555
Pubmed

Randomised trial of a decision aid and its timing for women being tested for a BRCA1/2 mutation.

BRCA1 BRCA2

2.93e-06260214735173
Pubmed

Coffee consumption and breast cancer risk among BRCA1 and BRCA2 mutation carriers.

BRCA1 BRCA2

2.93e-06260216032702
Pubmed

Oral contraceptive use and BRCA penetrance: a case-only study.

BRCA1 BRCA2

2.93e-06260219549808
Pubmed

Prevalence of BRCA1 and BRCA2 Mutations Among Patients With Ovarian, Primary Peritoneal, and Fallopian Tube Cancer in India: A Multicenter Cross-Sectional Study.

BRCA1 BRCA2

2.93e-06260234101484
Pubmed

Olaparib monotherapy in patients with advanced relapsed ovarian cancer and a germline BRCA1/2 mutation: a multistudy analysis of response rates and safety.

BRCA1 BRCA2

2.93e-06260226961146
Pubmed

Predicting BRCA1 and BRCA2 gene mutation carriers: comparison of PENN II model to previous study.

BRCA1 BRCA2

2.93e-06260220512419
Pubmed

Deleterious and ethnic-related BRCA1/2 mutations in tissue and blood of Egyptian colorectal cancer patients and its correlation with human papillomavirus.

BRCA1 BRCA2

2.93e-06260237804357
Pubmed

Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2.

BRCA1 BRCA2

2.93e-06260222053997
Pubmed

BRCA mutations in women with inflammatory breast cancer.

BRCA1 BRCA2

2.93e-06260229044548
Pubmed

Mutations in BRCA1 and BRCA2 differentially affect the tumor microenvironment and response to checkpoint blockade immunotherapy.

BRCA1 BRCA2

2.93e-06260233834176
Pubmed

Should genetic testing for BRCA1/2 be permitted for minors? Opinions of BRCA mutation carriers and their adult offspring.

BRCA1 BRCA2

2.93e-06260218200524
Pubmed

Enhanced response rate to pegylated liposomal doxorubicin in high grade serous ovarian carcinomas harbouring BRCA1 and BRCA2 aberrations.

BRCA1 BRCA2

2.93e-06260229298688
Pubmed

Fertility in women with BRCA mutations: a case-control study.

BRCA1 BRCA2

2.93e-06260219200971
Pubmed

Prevalence of BRCA mutations and founder effect in high-risk Hispanic families.

BRCA1 BRCA2

2.93e-06260216030099
Pubmed

Prevalence of BRCA1 and BRCA2 large genomic rearrangements in Tunisian high risk breast/ovarian cancer families: Implications for genetic testing.

BRCA1 BRCA2

2.93e-06260228212807
Pubmed

Genetic counseling impacts decision for prophylactic surgery for patients perceived to be at high risk for breast cancer.

BRCA1 BRCA2

2.93e-06260211448436
Pubmed

Rapid evolution of BRCA1 and BRCA2 in humans and other primates.

BRCA1 BRCA2

2.93e-06260225011685
Pubmed

Breast magnetic resonance imaging for screening high-risk women.

BRCA1 BRCA2

2.93e-06260223928241
Pubmed

Heterozygous BRCA1 and BRCA2 and Mismatch Repair Gene Pathogenic Variants in Children and Adolescents With Cancer.

BRCA1 BRCA2

2.93e-06260235980168
Pubmed

Tubal ligation and risk of ovarian cancer in carriers of BRCA1 or BRCA2 mutations: a case-control study.

BRCA1 BRCA2

2.93e-06260211377596
Pubmed

BRCA mutations and risk of prostate cancer in Ashkenazi Jews.

BRCA1 BRCA2

2.93e-06260215131025
Pubmed

Broad BRCA1 and BRCA2 mutational spectrum and high incidence of recurrent and novel mutations in the eastern Spain population.

BRCA1 BRCA2

2.93e-06260220033483
Pubmed

Health survey and assessment of the polymorphisms BRCA1/P871L, BRCA1/Q356R, and BRCA2/N372H in female gas station workers in Rio de Janeiro.

BRCA1 BRCA2

2.93e-06260228862356
Pubmed

BRCA1 and BRCA2 germline mutations in Moroccan breast/ovarian cancer families: novel mutations and unclassified variants.

BRCA1 BRCA2

2.93e-06260222425665
Pubmed

BRCA1/2 in high-risk African American women with breast cancer: providing genetic testing through various recruitment strategies.

BRCA1 BRCA2

2.93e-06260218752448
Pubmed

Peritoneal washing cytology in patients with BRCA1 or BRCA2 mutations undergoing risk-reducing salpingo-oophorectomies: a 10-year experience and reappraisal of its clinical utility.

BRCA1 BRCA2

2.93e-06260222425664
Pubmed

Identification of BRCA1/2 founder mutations in Southern Chinese breast cancer patients using gene sequencing and high resolution DNA melting analysis.

BRCA1 BRCA2

2.93e-06260222970155
Pubmed

Anti-müllerian hormone levels and antral follicle count in women with a BRCA1 or BRCA2 germline pathogenic variant: A retrospective cohort study.

BRCA1 BRCA2

2.93e-06260234304065
Pubmed

Absence of 185delAG and 6174delT Mutations among Breast Cancer Patients of Eastern India.

BRCA1 BRCA2

2.93e-06260226625823
Pubmed

Novel germline mutations and unclassified variants of BRCA1 and BRCA2 genes in Chinese women with familial breast/ovarian cancer.

BRCA1 BRCA2

2.93e-06260226852015
Pubmed

Meta-analysis of BRCA1 and BRCA2 penetrance.

BRCA1 BRCA2

2.93e-06260217416853
Pubmed

Power spectral analysis of mammographic parenchymal patterns for breast cancer risk assessment.

BRCA1 BRCA2

2.93e-06260218175183
Pubmed

Presence of crown-like structures in breast adipose tissue; differences between healthy controls, BRCA1/2 gene mutation carriers and breast cancer patients.

BRCA1 BRCA2

2.93e-06260238057686
Pubmed

Germline mutations in BRCA1 and BRCA2 in epithelial ovarian cancer patients in Brazil.

BRCA1 BRCA2

2.93e-06260227914478
Pubmed

BRCA1 and BRCA2 germline mutations in Korean breast cancer patients at high risk of carrying mutations.

BRCA1 BRCA2

2.93e-06260216455195
Pubmed

The poly(ADP-ribose) polymerase inhibitor niraparib (MK4827) in BRCA mutation carriers and patients with sporadic cancer: a phase 1 dose-escalation trial.

BRCA1 BRCA2

2.93e-06260223810788
Pubmed

Prognostic Impact of Breast-Conserving Therapy Versus Mastectomy of BRCA1/2 Mutation Carriers Compared With Noncarriers in a Consecutive Series of Young Breast Cancer Patients.

BRCA1 BRCA2

2.93e-06260229727326
Pubmed

Risk reducing surgery with peritoneal staging in BRCA1-2 mutation carriers. A prospective study.

BRCA1 BRCA2

2.93e-06260235871032
Pubmed

Recurrent BRCA1 and BRCA2 mutations in breast cancer patients of African ancestry.

BRCA1 BRCA2

2.93e-06260222739995
Pubmed

The impact of a panel of 18 SNPs on breast cancer risk in women attending a UK familial screening clinic: a case-control study.

BRCA1 BRCA2

2.93e-06260227794048
Pubmed

Breast cancer surgery trend changes since the introduction of BRCA1/2 mutation screening: a retrospective cohort analysis of 158 mutation carriers treated at a single institution.

BRCA1 BRCA2

2.93e-06260220972632
Pubmed

BRCA1 and BRCA2 germline mutations in Korean ovarian cancer patients.

BRCA1 BRCA2

2.93e-06260219499246
Pubmed

Comprehensive mutational analysis of BRCA1/BRCA2 for Korean breast cancer patients: evidence of a founder mutation.

BRCA1 BRCA2

2.93e-06260219656164
Pubmed

Effect of pregnancy as a risk factor for breast cancer in BRCA1/BRCA2 mutation carriers.

BRCA1 BRCA2

2.93e-06260215986445
Pubmed

Effect of BRCA1/2 mutations on long-term survival of patients with invasive ovarian cancer: the national Israeli study of ovarian cancer.

BRCA1 BRCA2

2.93e-06260218165636
Pubmed

Large genomic rearrangements in BRCA1 and BRCA2: implications for patient care.

BRCA1 BRCA2

2.93e-06260223615136
Pubmed

Clinicopathologic features and BRCA mutations in primary fallopian tube cancer in Japanese women.

BRCA1 BRCA2

2.93e-06260229982601
Pubmed

Breast cancer detection and tumor characteristics in BRCA1 and BRCA2 mutation carriers.

BRCA1 BRCA2

2.93e-06260228343309
Pubmed

BRCA1 and BRCA2 genetic testing in Hispanic patients: mutation prevalence and evaluation of the BRCAPRO risk assessment model.

BRCA1 BRCA2

2.93e-06260217925560
Pubmed

Intratumor Heterogeneity of Homologous Recombination Deficiency in Primary Breast Cancer.

BRCA1 BRCA2

2.93e-06260227601588
Pubmed

Tamoxifen and risk of contralateral breast cancer for BRCA1 and BRCA2 mutation carriers.

BRCA1 BRCA2

2.93e-06260223918944
Pubmed

Genomic Analysis of Circulating Tumor DNA in 3,334 Patients with Advanced Prostate Cancer Identifies Targetable BRCA Alterations and AR Resistance Mechanisms.

BRCA1 BRCA2

2.93e-06260233558422
Pubmed

Breast cancer risk associated with BRCA1/2 variants in the Pakistani population.

BRCA1 BRCA2

2.93e-06260230430339
Pubmed

Satisfaction with prophylactic risk-reducing salpingo-oophorectomy in BRCA mutation carriers is very high and little dependent on the participants' characteristics at surgery: a prospective study.

BRCA1 BRCA2

2.93e-06260233534430
Pubmed

BRCA 1, 2 mutation and earlier menopause: could BRCA 1,2 be used as predictor of menopause?

BRCA1 BRCA2

2.93e-06260234137566
Pubmed

BRCA1/2 Mutation Detection in the Tumor Tissue from Selected Polish Patients with Breast Cancer Using Next Generation Sequencing.

BRCA1 BRCA2

2.93e-06260233918338
Pubmed

Effect of Oophorectomy on Survival After Breast Cancer in BRCA1 and BRCA2 Mutation Carriers.

BRCA1 BRCA2

2.93e-06260226181175
Pubmed

Mutational analysis of BRCA1 and BRCA2 in Mediterranean Spanish women with early-onset breast cancer: identification of three novel pathogenic mutations.

BRCA1 BRCA2

2.93e-06260214517958
Pubmed

Better life expectancy in women with BRCA2 compared with BRCA1 mutations is attributable to lower frequency and later onset of ovarian cancer.

BRCA1 BRCA2

2.93e-06260218559571
Pubmed

BRCA1-2 diagnostic workflow from next-generation sequencing technologies to variant identification and final report.

BRCA1 BRCA2

2.93e-06260227225819
Pubmed

BRCA1 and BRCA2 mutation prevalence and clinical characteristics of a population-based series of ovarian cancer cases from Denmark.

BRCA1 BRCA2

2.93e-06260218559594
Pubmed

Characterization of BRCA1 and BRCA2 genetic variants in a cohort of Bahraini breast cancer patients using next-generation sequencing.

BRCA1 BRCA2

2.93e-06260231131559
Pubmed

The pathology of familial breast cancer: predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2.

BRCA1 BRCA2

2.93e-06260211981002
Pubmed

Identification of twenty-nine novel germline unclassified variants of BRCA1 and BRCA2 genes in 1400 Italian individuals.

BRCA1 BRCA2

2.93e-06260229020660
Pubmed

An emerging entity: pancreatic adenocarcinoma associated with a known BRCA mutation: clinical descriptors, treatment implications, and future directions.

BRCA1 BRCA2

2.93e-06260221934105
Pubmed

Revertant mosaicism for family mutations is not observed in BRCA1/2 phenocopies.

BRCA1 BRCA2

2.93e-06260228199346
Pubmed

Results of a population-based screening for hereditary breast cancer in a region of North-Central Italy: contribution of BRCA1/2 germ-line mutations.

BRCA1 BRCA2

2.93e-06260218092194
Pubmed

Diet, lifestyle and BRCA-related breast cancer risk among French-Canadians.

BRCA1 BRCA2

2.93e-06260216541324
Pubmed

Investigating the relationship between BRCA1 and BRCA2 genes methylation profile and sperm DNA fragmentation in infertile men.

BRCA1 BRCA2

2.93e-06260231095775
Pubmed

Ethnic-specificity, evolution origin and deleteriousness of Asian BRCA variation revealed by over 7500 BRCA variants derived from Asian population.

BRCA1 BRCA2

2.93e-06260236385461
Pubmed

Screening for Genetic Testing in Breast Cancer - Are We Missing the Full Picture?

BRCA1 BRCA2

2.93e-06260226254840
Pubmed

Contribution of BRCA1 germ-line mutations to breast cancer in Greece: a hospital-based study of 987 unselected breast cancer cases.

BRCA1 BRCA2

2.93e-06260219491894
Pubmed

Young age at first pregnancy does protect against early onset breast cancer in BRCA1 and BRCA2 mutation carriers.

BRCA1 BRCA2

2.93e-06260229116468
Pubmed

BRCA1 and BRCA2 mutations in males with familial breast and ovarian cancer syndrome. Results of a Spanish multicenter study.

BRCA1 BRCA2

2.93e-06260226026974
Pubmed

Etiology of familial breast cancer with undetected BRCA1 and BRCA2 mutations: clinical implications.

BRCA1 BRCA2

2.93e-06260224306927
Pubmed

[Germline mutations in the BRCA1 and BRCA2 genes from breast cancer families in China Han people].

BRCA1 BRCA2

2.93e-06260215059511
Pubmed

The impact of reproductive life on breast cancer risk in women with family history or BRCA mutation.

BRCA1 BRCA2

2.93e-06260227880720
Pubmed

BRCA1 and BRCA2 mutations in Turkish familial and non-familial ovarian cancer patients: a high incidence of mutations in non-familial cases.

BRCA1 BRCA2

2.93e-06260212112655
Pubmed

Can soy phytoestrogens decrease DNA methylation in BRCA1 and BRCA2 oncosuppressor genes in breast cancer?

BRCA1 BRCA2

2.93e-06260222339411
Pubmed

Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants.

BRCA1 BRCA2

2.93e-06260234906479
Pubmed

Validation of Version 3.0 of the Breast Cancer Genetics Referral Screening Tool (B-RST™).

BRCA1 BRCA2

2.93e-06260229740170
Pubmed

Elevated expression of Ki-67 identifies aggressive prostate cancers but does not distinguish BRCA1 or BRCA2 mutation carriers.

BRCA1 BRCA2

2.93e-06260220043088
Pubmed

Utilization of breast cancer screening in a clinically based sample of women after BRCA1/2 testing.

BRCA1 BRCA2

2.93e-06260212376518
Pubmed

Characterization and in silico analyses of the BRCA1/2 variants identified in individuals with personal and/or family history of BRCA-related cancers.

BRCA1 BRCA2

2.93e-06260232599251
Pubmed

Oral contraceptive use and breast or ovarian cancer risk in BRCA1/2 carriers: a meta-analysis.

BRCA1 BRCA2

2.93e-06260220537530
Pubmed

Multiple founder effects and geographical clustering of BRCA1 and BRCA2 families in Finland.

BRCA1 BRCA2

2.93e-06260211039575
InteractionPHF21A interactions

ZFHX4 BRCA2 KIF14 ZFHX3 EXOC1 ICE1 OBI1 HSPA6 GOLGB1

7.43e-07343609int:PHF21A
InteractionNUP43 interactions

RIF1 SETD2 PBRM1 BRCA1 LMNA BRCA2 BAZ2B ZFHX3 ICE1 HSPA6 ELP4

2.01e-066256011int:NUP43
InteractionMAGEA9 interactions

PI4K2B RC3H2 ZFHX4 BRCA2 CEP95 KIF14 ITPR2

2.74e-06208607int:MAGEA9
InteractionKDM1A interactions

BRCA1 ZFHX4 BRCA2 ZNF451 ZBTB21 CEP70 KIF14 ZFHX3 EXOC1 ICE1 OBI1 HSPA6 GOLGB1

3.10e-069416013int:KDM1A
InteractionMDC1 interactions

RAG1 RIF1 SETD2 BRCA1 LMNA ACD BRCA2 KIF14 ICE1

3.50e-06414609int:MDC1
InteractionNINL interactions

BRCA1 LMNA BRCA2 MYO5A CEP95 CFL1 KIF14 ZFHX3 CEP128

7.91e-06458609int:NINL
InteractionCEP135 interactions

BRCA2 CEP95 CEP70 KIF14 CEP128 GOLGB1 ESF1

1.58e-05272607int:CEP135
InteractionSNRNP40 interactions

RC3H2 SETD2 BRCA1 LMNA BRCA2 BAZ2B ZNF451 RAVER2 ZBTB21 ZFHX3

1.68e-056376010int:SNRNP40
InteractionCSNK2A3 interactions

ANKRD36B ABR KIF14 ANKRD36 ANKRD36C

1.90e-05110605int:CSNK2A3
InteractionFLNA interactions

RC3H2 ADRB2 BRCA1 LMNA BRCA2 MYO5A CFL1 KIF14 HSPA6 MYO5C

1.95e-056486010int:FLNA
InteractionGAPDH interactions

RIF1 ADRB2 BRCA1 LMNA ACD CFL1 KIF14 ZFHX3 ANKRD36 HSPA6

3.17e-056866010int:GAPDH
InteractionSERPINH1 interactions

ADRB2 BRCA1 BRCA2 CFL1 CEP70 KIF14 ROS1

3.37e-05306607int:SERPINH1
InteractionNPM1 interactions

RC3H2 SETD2 PBRM1 BRCA1 LMNA BRCA2 MYO5A CFL1 ZBTB21 SYCP1 KIF14 NEB ESF1

4.19e-0512016013int:NPM1
InteractionSLX4 interactions

BRCA1 LMNA BRCA2 BAZ2B CFL1 ZNF451 ZBTB21 HSPA6 ESF1

4.57e-05572609int:SLX4
InteractionCDK16 interactions

RC3H2 BRCA1 LMNA ZBTB21 KIF14

4.57e-05132605int:CDK16
InteractionCALM3 interactions

RC3H2 ADRB2 CFL1 ROS1 MYO5C EPHA4 ITPR2

6.93e-05343607int:CALM3
InteractionTCEANC interactions

BRCA1 LMNA TNIP3 CEP70 OBI1

7.15e-05145605int:TCEANC
InteractionPOT1 interactions

RIF1 BRCA1 ACD CFL1 ZNF790 MYO5C

7.31e-05237606int:POT1
InteractionFAM118B interactions

LMNA CEP70 CEP126 EPHA4

8.59e-0578604int:FAM118B
InteractionZNF790 interactions

ACD ZNF790

8.67e-055602int:ZNF790
InteractionTMOD4 interactions

MYO5A NEB MYO5C

8.68e-0529603int:TMOD4
InteractionSLU7 interactions

RC3H2 SETD2 LMNA CEP70 KIF14

1.01e-04156605int:SLU7
InteractionODF2 interactions

BRCA1 CFL1 KIF14 CEP128 MAP3K1

1.07e-04158605int:ODF2
InteractionCBX3 interactions

RIF1 SETD2 BRCA1 LMNA ZNF451 ZNF184 ZBTB21 KIF14 ESF1

1.16e-04646609int:CBX3
InteractionPOLN interactions

BRCA1 BRCA2 ELP4

1.17e-0432603int:POLN
InteractionCFAP184 interactions

SETD2 BRCA2 CEP95 EXOC1 ICE1

1.21e-04162605int:CFAP184
InteractionEEA1 interactions

USP8 ADRB2 LMNA KIF14 EEA1

1.21e-04162605int:EEA1
InteractionZNF25 interactions

ADRB2 LMNA

1.30e-046602int:ZNF25
InteractionCLIC1 interactions

BRCA1 LMNA ZNF184 KIF14 MYO5C

1.31e-04165605int:CLIC1
InteractionKRT38 interactions

LMNA BRCA2 EEA1 KRT79 MYO5C

1.60e-04172605int:KRT38
InteractionBRIP1 interactions

PBRM1 BRCA1 LMNA BRCA2

1.63e-0492604int:BRIP1
InteractionPIAS4 interactions

RIF1 BRCA1 LMNA BRCA2 ZNF445

1.64e-04173605int:PIAS4
InteractionZNF594 interactions

ANKRD36B ZNF594

1.81e-047602int:ZNF594
InteractionCXCL6 interactions

SETD2 MYO5A MYO5C

1.81e-0437603int:CXCL6
InteractionSFR1 interactions

PBRM1 CEP70 EXOC1

1.81e-0437603int:SFR1
InteractionCDC5L interactions

RC3H2 RIF1 BRCA1 LMNA ZNF451 KIF14 EXOC1 PSTPIP2 HSPA6 GOLGB1

1.97e-048556010int:CDC5L
InteractionCWF19L2 interactions

BRCA1 LMNA BRCA2 CEP70 KIF14

2.08e-04182605int:CWF19L2
InteractionTULP2 interactions

PBRM1 BRCA1 MYO5C

2.12e-0439603int:TULP2
InteractionZBTB14 interactions

BRCA1 BRCA2 BAZ2B ZBTB21

2.25e-04100604int:ZBTB14
InteractionKRT37 interactions

LMNA ANKRD36 EEA1 KRT79

2.25e-04100604int:KRT37
InteractionSHANK1 interactions

USP8 BRCA2 KIF14

2.47e-0441603int:SHANK1
InteractionAP2A1 interactions

RC3H2 ADRB2 BRCA1 KIF14 CEP128 MYO5C

2.59e-04299606int:AP2A1
InteractionGOLGA2 interactions

ZNF594 BAZ2B CEP95 ZBTB21 KIF14 ZFHX3 ICE1 ANKRD36 GOLGB1

2.98e-04733609int:GOLGA2
InteractionPHIP interactions

PBRM1 LMNA ZFHX4 KIF14 ZFHX3

3.00e-04197605int:PHIP
InteractionDCAF12 interactions

SETD2 BRCA2 BAZ2B ZFHX3

3.02e-04108604int:DCAF12
InteractionSMTN interactions

BRCA1 LMNA KIF14

3.05e-0444603int:SMTN
InteractionPIBF1 interactions

TNIP3 CEP70 ZFHX3 EEA1 CEP128

3.21e-04200605int:PIBF1
InteractionORC2 interactions

BRCA1 LMNA KIF14 OBI1

3.24e-04110604int:ORC2
InteractionNDC80 interactions

CEP95 KIF14 EXOC1 ICE1 CEP128 MYO5C

3.25e-04312606int:NDC80
InteractionH2AX interactions

PBRM1 BRCA1 LMNA BRCA2 CFL1 KIF14 PHF14 NEB

3.56e-04593608int:H2AX
InteractionCTTN interactions

LMNA ACD BRCA2 MYO5A CFL1 KIF14 MYO5C

3.67e-04450607int:CTTN
InteractionHDAC1 interactions

BRCA1 ZFHX4 BRCA2 ZBTB21 KIF14 PHF14 ZFHX3 CEP128 OBI1 HSPA6 GOLGB1

3.77e-0411086011int:HDAC1
InteractionXRCC6 interactions

RC3H2 RIF1 BRCA1 LMNA ACD BRCA2 KIF14 ZFHX3 ICE1 ESF1

3.79e-049286010int:XRCC6
InteractionHDAC6 interactions

PBRM1 ADRB2 LMNA BRCA2 MYO5A CFL1 CEP70 KIF14 HSPA6 GOLGB1

3.82e-049296010int:HDAC6
InteractionAURKB interactions

RC3H2 RIF1 SETD2 ABR LMNA BRCA2 KIF14 ZNF782 OBI1

3.92e-04761609int:AURKB
InteractionYWHAQ interactions

USP8 ADRB2 BRCA1 LMNA CEP95 CFL1 ZBTB21 KIF14 NEB GOLGB1 MAP3K1

4.07e-0411186011int:YWHAQ
InteractionYWHAZ interactions

PDC USP8 BRCA1 LMNA MYO5A CEP95 CFL1 ZBTB21 KIF14 CEP126 NEB MAP3K1

4.37e-0413196012int:YWHAZ
InteractionZNF239 interactions

LMNA CEP70

4.71e-0411602int:ZNF239
InteractionHSP90AB1 interactions

USP8 RC3H2 BRCA1 ACD BRCA2 BAZ2B KIF14 ROS1 NEB HSPA6

4.95e-049606010int:HSP90AB1
Cytoband15q21

MYO5A MYO5C

9.17e-051160215q21
CytobandEnsembl 112 genes in cytogenetic band chr3p21

CACNA1D SETD2 PBRM1 ZNF445

7.93e-04316604chr3p21
CytobandEnsembl 112 genes in cytogenetic band chr2q11

ANKRD36B ANKRD36 ANKRD36C

1.08e-03153603chr2q11
CytobandEnsembl 112 genes in cytogenetic band chr15q21

USP8 MYO5A MYO5C

1.64e-03177603chr15q21
CytobandEnsembl 112 genes in cytogenetic band chr2q23

RIF1 NEB

2.22e-0353602chr2q23
Cytoband11p13

RAG1 ELP4

2.47e-035660211p13
Cytoband2q11.2

ANKRD36B ANKRD36

4.05e-03726022q11.2
CytobandEnsembl 112 genes in cytogenetic band chr5q32

PDE6A ADRB2

4.97e-0380602chr5q32
GeneFamilyMyosins, class V

MYO5A MYO5C

1.73e-0534421100
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF594 ZNF451 ZNF184 ZNF790 ZBTB21 ZFHX3 ZNF782 ZNF445

2.97e-0471844828
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZFHX4 ZFHX3

5.96e-0415442529
GeneFamilyRing finger proteins|Fanconi anemia complementation groups|Protein phosphatase 1 regulatory subunits|BRCA1 A complex|BRCA1 B complex|BRCA1 C complex

BRCA1 BRCA2

1.07e-0320442548
GeneFamilyZinc fingers CCCH-type

RC3H2 ZC3H6

3.27e-033544273
GeneFamilyRing finger proteins

RAG1 RC3H2 BRCA1 OBI1

4.41e-0327544458
GeneFamilyPHD finger proteins

BAZ2B PHF14

2.02e-029044288
GeneFamilyAnkyrin repeat domain containing

ANKRD36B ANKRD36 ANKRD36C

2.10e-02242443403
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

PI4K2B USP8 RIF1 PBRM1 BRCA1 MYO5A BAZ2B CEP70 KIF14 EXOC1 EEA1 OBI1 GOLGB1 ESF1 ITPR2

1.52e-116566015M18979
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

RIF1 SETD2 BRCA1 BRCA2 BAZ2B ZNF451 KIF14 PHF14 ZFHX3 EPHA4

2.25e-058566010M4500
CoexpressionE2F3_UP.V1_DN

RIF1 BRCA2 ZNF782 HSPA6 ESF1

3.62e-05163605M2704
CoexpressionHE_LIM_SUN_FETAL_LUNG_C4_CYCLING_T_CELL

ANKRD36B RIF1 PBRM1 BRCA1 ACD BRCA2 KIF14 ANKRD36 ANKRD36C MAP3K1

4.92e-059396010M45768
CoexpressionGSE14415_INDUCED_TREG_VS_FAILED_INDUCED_TREG_DN

BRCA1 BRCA2 MYO5A KIF14 EEA1

5.51e-05178605M2952
CoexpressionGSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_2H_UP

BRCA1 BRCA2 MYO5A KIF14 NEB

6.28e-05183605M2993
CoexpressionDAZARD_RESPONSE_TO_UV_NHEK_DN

RIF1 ADRB2 BAZ2B ZNF451 KIF14 ICE1

6.37e-05300606M8702
CoexpressionGSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_UP

BAZ2B ZNF451 EXOC1 ANKRD36 GOLGB1

9.56e-05200605M9889
CoexpressionGSE32164_RESTING_DIFFERENTIATED_VS_CMYC_INHIBITED_MACROPHAGE_UP

PDE6A ADRB2 MYO5A EEA1 MAP3K1

9.56e-05200605M8532
CoexpressionLEE_EARLY_T_LYMPHOCYTE_UP

RAG1 CEP70 KIF14 CEP128

1.24e-04111604M7357
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

RIF1 BRCA1 BRCA2 MYO5A ZNF184 CEP70 PHF14 ESF1

1.71e-06311578Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500

RIF1 ADRB2 BRCA1 BRCA2 MYO5A ZNF184 CEP70 KIF14 PHF14 CEP126 CEP128 OBI1 ESF1 MYO5C

1.62e-0514145714facebase_RNAseq_e10.5_Emin_MedNas_2500
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500_K1

RIF1 BRCA1 BRCA2 MYO5A ZNF184 CEP70 KIF14 PHF14 CEP126 CEP128 OBI1 ESF1

1.98e-0510605712facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlasDevelopingGonad_e18.5_testes_emap-11164_k-means-cluster#1_top-relative-expression-ranked_500

RC3H2 RIF1 BAZ2B CFL1 ESF1

3.69e-05140575gudmap_developingGonad_e18.5_testes_500_k1
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000

RC3H2 RIF1 MYO5A SYCP1 EEA1 NEB KRT79 ESF1 ITPR2 ZNF445

3.73e-057785710gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlasDevelopingGonad_e12.5_testes_emap-29069_k-means-cluster#4_top-relative-expression-ranked_500

RC3H2 RIF1 BRCA1 BAZ2B CFL1 ESF1

4.49e-05241576gudmap_developingGonad_e12.5_testes_k4_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#5_top-relative-expression-ranked_1000

RIF1 MYO5A ZNF451 ZFHX3 ICE1 ZC3H6 ELP4 EPHA4

4.79e-05492578gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000_k5
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_1000

RC3H2 RIF1 PBRM1 ZFHX4 CCDC30 ZNF451 ZFHX3 MAP3K1 ESF1 ZNF445

4.92e-058045710gudmap_developingGonad_e12.5_ovary_1000
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_1000

RIF1 BRCA1 BRCA2 CEP95 ZNF451 SYCP1 CEP70 KIF14 ZC3H6 ESF1

5.24e-058105710gudmap_dev gonad_e13.5_M_GermCell_Oct_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000

PI4K2B ABR BRCA1 ZFHX4 BRCA2 RAVER2 ZNF184 ZNF790 CEP70 PHF14 ZFHX3

5.25e-059855711Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_1000

RIF1 ZFHX4 MYO5A ZNF451 ZFHX3 ICE1 NEB ZC3H6 ELP4 EPHA4

6.83e-058365710gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000
CoexpressionAtlasDevelopingGonad_e16.5_testes_emap-8444_k-means-cluster#1_top-relative-expression-ranked_500

RC3H2 RIF1 BAZ2B CFL1 ESF1

8.53e-05167575gudmap_developingGonad_e16.5_testes_500_k1
CoexpressionAtlasDevelopingGonad_P2_ovary_emap-30224_k-means-cluster#4_top-relative-expression-ranked_1000

RIF1 MYO5A SYCP1 EEA1 ITPR2

8.77e-05168575gudmap_developingGonad_P2_ovary_1000_k4
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

RIF1 BRCA1 BRCA2 MYO5A ZNF184 CEP70 PHF14 ZFHX3 CEP126 CEP128 OBI1 ESF1

1.04e-0412575712facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasDevelopingGonad_e14.5_ testes_emap-6710_k-means-cluster#4_top-relative-expression-ranked_500

RC3H2 RIF1 BAZ2B CFL1 ESF1

1.34e-04184575gudmap_developingGonad_e14.5_ testes_500_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_500

RIF1 ZFHX4 ZNF451 ZFHX3 NEB ZC3H6 EPHA4

1.45e-04429577gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500
CoexpressionAtlasDevelopingGonad_e11.5_testes and mesonephros_emap-3226_top-relative-expression-ranked_500

RC3H2 RIF1 ZFHX4 BAZ2B CFL1 OBI1 ESF1

1.58e-04435577gudmap_developingGonad_e11.5_testes and mesonephros_500
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_k-means-cluster#1_top-relative-expression-ranked_1000

RIF1 BRCA1 ZNF451 CEP70 KIF14 ESF1

2.63e-04333576gudmap_dev gonad_e13.5_M_GermCell_Oct_k1_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#5_top-relative-expression-ranked_1000

RIF1 ZFHX4 MYO5A ZNF451 ZFHX3 ELP4 EPHA4

2.80e-04478577gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000_k5
CoexpressionAtlasDevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_1000

RC3H2 RIF1 PBRM1 ZFHX4 ZNF451 ZFHX3 OBI1 ESF1 ZNF445

2.98e-04815579gudmap_developingGonad_e11.5_ovary + mesonephros_1000
CoexpressionAtlasDevelopingGonad_P2_testes_emap-30171_k-means-cluster#2_top-relative-expression-ranked_1000

RC3H2 RIF1 BRCA1 BAZ2B CFL1 ESF1

3.38e-04349576gudmap_developingGonad_P2_testes_1000_k2
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

RIF1 SETD2 BRCA1 BRCA2 MYO5A ZNF184 PHF14 EEA1 ESF1

3.43e-04831579Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlasDevelopingGonad_e14.5_ testes_emap-6710_k-means-cluster#3_top-relative-expression-ranked_200

RIF1 CFL1 ESF1

3.69e-0452573gudmap_developingGonad_e14.5_ testes_200_k3
CoexpressionAtlasDevelopingGonad_e11.5_testes_emap-3226_top-relative-expression-ranked_1000

RC3H2 RIF1 BRCA1 ZFHX4 BAZ2B CFL1 ZFHX3 OBI1 ESF1

3.81e-04843579gudmap_developingGonad_e11.5_testes_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#2_top-relative-expression-ranked_200

ZFHX4 ZFHX3 EPHA4

4.13e-0454573gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_200_k2
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

RIF1 BRCA1 BRCA2 MYO5A ZNF184 CEP70 PHF14 ZFHX3 CEP126 CEP128 OBI1 ESF1

4.14e-0414595712facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlasDevelopingGonad_P2_testes_emap-30171_k-means-cluster#3_top-relative-expression-ranked_500

RIF1 BAZ2B CFL1 ESF1

4.89e-04136574gudmap_developingGonad_P2_testes_500_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#4_top-relative-expression-ranked_500

RIF1 ZFHX4 ZNF451 ZFHX3 EPHA4

5.23e-04247575gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#3_top-relative-expression-ranked_500

RIF1 ZFHX4 ZFHX3 ELP4 EPHA4

5.43e-04249575gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_500_k3
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_500

RIF1 BRCA1 BRCA2 SYCP1 KIF14 ZC3H6

5.68e-04385576gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_500
CoexpressionAtlasdev gonad_e12.5_M_GermCellTestis_Oct_top-relative-expression-ranked_500

RIF1 BRCA1 BRCA2 ZNF451 SYCP1 KIF14

5.84e-04387576gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_500
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_500

RIF1 BRCA2 ZNF451 SYCP1 CEP70 KIF14

6.59e-04396576gudmap_dev gonad_e13.5_M_GermCell_Oct_500
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_500

RIF1 BRCA1 BRCA2 ZNF451 SYCP1 KIF14

7.50e-04406576gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_500
CoexpressionAtlasDevelopingGonad_e12.5_testes_emap-29069_top-relative-expression-ranked_500

RC3H2 RIF1 BRCA1 BAZ2B CFL1 ESF1

7.50e-04406576gudmap_developingGonad_e12.5_testes_500
CoexpressionAtlasDevelopingGonad_e14.5_ testes_emap-6710_top-relative-expression-ranked_500

RC3H2 RIF1 BAZ2B CFL1 SYCP1 ESF1

7.99e-04411576gudmap_developingGonad_e14.5_ testes_500
CoexpressionAtlasDevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_500

RIF1 PBRM1 ZFHX4 ZFHX3 ESF1 ZNF445

8.62e-04417576gudmap_developingGonad_e11.5_ovary + mesonephros_500
CoexpressionAtlasfacebase_RNAseq_e10.5_NeuroEpith_central_2500_K4

RC3H2 BRCA1 BRCA2 MYO5A CEP95 ZNF184 KIF14 PHF14 CEP126 OBI1 ESF1

9.13e-0413705711facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4
CoexpressionAtlasDevelopingGonad_e14.5_ testes_emap-6710_k-means-cluster#5_top-relative-expression-ranked_1000

RC3H2 RIF1 BRCA1 BAZ2B CFL1 ESF1

9.98e-04429576gudmap_developingGonad_e14.5_ testes_1000_k5
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#1_top-relative-expression-ranked_1000

CACNA1D SETD2 PHF14 ITPR2

1.03e-03166574gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k1_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#3

RIF1 ZFHX4 BRCA2 CEP70 GOLGB1 ESF1

1.03e-03432576Facebase_RNAseq_e10.5_Maxillary Arch_1000_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1

SETD2 BRCA1 BRCA2 CEP95 ZNF184 CEP70 PHF14 EEA1

1.07e-03780578Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#3

BRCA1 BRCA2 ZNF184 CEP70 PHF14

1.09e-03291575Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000_K3
CoexpressionAtlasDevelopingGonad_e11.5_testes_emap-3226_top-relative-expression-ranked_500

RC3H2 RIF1 ZFHX4 CFL1 OBI1 ESF1

1.10e-03437576gudmap_developingGonad_e11.5_testes_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000

RIF1 SETD2 BRCA1 BRCA2 MYO5A ZNF184 CEP70 PHF14 ESF1

1.19e-03989579Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#4

BRCA2 CEP70 PHF14 CEP126 GOLGB1

1.21e-03298575Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000_K4
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000

RC3H2 RIF1 MYO5A SYCP1 MAP3K1 ESF1 ITPR2 ZNF445

1.21e-03795578gudmap_developingGonad_e16.5_ovary_1000
CoexpressionAtlasdev gonad_e12.5_M_GermCellTestis_Oct_top-relative-expression-ranked_1000

RIF1 BRCA1 BRCA2 ZNF451 SYCP1 CEP70 KIF14 ESF1

1.21e-03795578gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_1000
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000

RC3H2 RIF1 BAZ2B ZNF451 ZFHX3 MAP3K1 ESF1 ZNF445

1.27e-03801578gudmap_developingGonad_e14.5_ epididymis_1000
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_1000

RC3H2 RIF1 PBRM1 BRCA1 ZNF451 MAP3K1 ESF1 ZNF445

1.33e-03806578gudmap_developingGonad_e12.5_epididymis_1000
CoexpressionAtlasDevelopingGonad_e11.5_testes and mesonephros_emap-3226_top-relative-expression-ranked_200

RC3H2 ZFHX4 CFL1 ESF1

1.36e-03179574gudmap_developingGonad_e11.5_testes and mesonephros_200
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000

RIF1 BRCA1 BRCA2 ZNF451 SYCP1 KIF14 ZC3H6 ESF1

1.48e-03820578gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlasfacebase_RNAseq_e10.5_MandArch_2500_K1

RIF1 BRCA1 BRCA2 ZNF184 CEP70 PHF14 ZFHX3 CEP126 ESF1 ITPR2

1.57e-0312415710facebase_RNAseq_e10.5_MandArch_2500_K1
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500_k-means-cluster#5

BRCA2 ZNF184 CEP70 PHF14

1.57e-03186574Facebase_RNAseq_e10.5_Mandibular Arch_500_K5
CoexpressionAtlasfacebase_RNAseq_e10.5_MaxArch_2500_K3

RIF1 BRCA2 ZNF184 CEP70 PHF14 ZFHX3 CEP126 CEP128 ESF1 EPHA4

1.67e-0312525710facebase_RNAseq_e10.5_MaxArch_2500_K3
CoexpressionAtlasDevelopingGonad_e12.5_testes_emap-29069_k-means-cluster#5_top-relative-expression-ranked_200

RIF1 CFL1 ESF1

1.71e-0388573gudmap_developingGonad_e12.5_testes_k5_200
CoexpressionAtlaskidney_P2_CapMes_Crym_k-means-cluster#1_top-relative-expression-ranked_1000

BRCA1 CEP126 OBI1 EPHA4

1.73e-03191574gudmap_kidney_P2_CapMes_Crym_k1_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#3_top-relative-expression-ranked_200

ZFHX4 EPHA4

1.73e-0323572DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k3_200
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3

RIF1 BRCA1 BRCA2 ESF1

1.76e-03192574Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3
CoexpressionAtlasDevelopingGonad_e11.5_testes and mesonephros_emap-3226_top-relative-expression-ranked_1000

RC3H2 RIF1 BRCA1 ZFHX4 BAZ2B CFL1 OBI1 ESF1

1.77e-03844578gudmap_developingGonad_e11.5_testes and mesonephros_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_1000

RIF1 ZFHX4 MYO5A ZNF451 ZFHX3 NEB ELP4 EPHA4

1.85e-03850578gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#5_top-relative-expression-ranked_200

ZFHX4 ZFHX3 EPHA4

1.88e-0391573gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_200_k5
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500

PI4K2B BRCA1 ZFHX4 BRCA2 CEP70 ZFHX3

2.00e-03492576Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500
ToppCellmoderate-Epithelial-FOXN4+|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

BRCA2 ZBTB21 ANKRD36 CEP126 ANKRD36C MYO5C

2.45e-071946065dffa578149104dda33774361e9e77b227b5f1ce
ToppCellmoderate-Epithelial-FOXN4+|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

BRCA1 BRCA2 CEP95 ZBTB21 ANKRD36 CEP128

2.45e-07194606dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

LMNA PHF14 ANKRD36 ANKRD36C GOLGB1 ESF1

2.69e-071976060fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TTC29 TNIP3 ZFHX3 ROS1 ITPR2

2.98e-06166605739dfbe927f409821ff23aca6e47ebe78f57e859
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ANKRD36B CEP95 ANKRD36 GOLGB1 MAP3K1

3.07e-06167605ced6ed9b412739c6ced622523347c10295edbf53
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TTC29 TNIP3 ZFHX3 ROS1 ITPR2

3.35e-0617060584d49a1f2989d98bd0acf9ec2d59f1042fc0f55b
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TTC29 TNIP3 ZFHX3 ROS1 ITPR2

3.55e-06172605adc09c4d1b63fe84150516beb692db1e7f7ac980
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TTC29 TNIP3 ZFHX3 ROS1 ITPR2

3.55e-06172605cecfe5cf20f317ea01b4604789e07a14481c4cd6
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANKRD36B BAZ2B ANKRD36C GOLGB1 MYO5C

4.31e-061796056e965e424eebef50f0202cff75f458be395cfca1
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

ZFHX4 MYO5A SCN7A EEA1 ITPR2

4.93e-0618460567164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellBrain_organoid-organoid_Kanton_Nature|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.

ANKRD36B BAZ2B PHF14 ICE1 ANKRD36C

5.06e-06185605857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCellControl-Endothelial-Endothelial-FOXM1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BRCA1 BRCA2 SYCP1 KIF14 CEP128

5.62e-061896051e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANKRD36B TNIP3 ANKRD36 ANKRD36C GOLGB1

6.54e-061956053f8ed20ad17afe1545e574e5ca5fe33c3704c7f3
ToppCell(1)_T_cells-(1)_T_CD4_naive|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

ANKRD36B SETD2 PHF14 ANKRD36 ANKRD36C

6.54e-06195605d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

ANKRD36B ANKRD36 CEP126 EEA1 GOLGB1

7.22e-0619960561b1ed2db71b96157b92b7535d1955a4033098da
ToppCellNeuronal-Excitatory-eE(FEZF2_SLC17A7)|Neuronal / cells hierarchy compared to all cells using T-Statistic

TTC29 TNIP3 ZFHX3 ROS1 ITPR2

7.39e-06200605501cd2b4e55444fc5fdd93ebbcfc0616442b110b
ToppCellSepsis-URO-Lymphocyte-T/NK-T/NK_proliferative|URO / Disease, condition lineage and cell class

BRCA1 BRCA2 KIF14 ANKRD36C CEP128

7.39e-06200605f277db6cc288a52a5426120c1067608700ee8ccc
ToppCellControl_saline-Endothelial-Endothelial-FOXM1|Control_saline / Treatment groups by lineage, cell group, cell type

BRCA1 BRCA2 CEP70 KIF14 CEP128

7.39e-062006059bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCellNeuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_1(EFTUD1P1)---L5-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

TTC29 TNIP3 ZFHX3 ROS1 ITPR2

7.39e-06200605046a3a4d7e4d84ee4252a695ffd4a6aee8b77070
ToppCellNeuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_1(EFTUD1P1)-|Neuronal / cells hierarchy compared to all cells using T-Statistic

TTC29 TNIP3 ZFHX3 ROS1 ITPR2

7.39e-06200605893cc7f6b9794da90aa0c9d721b8647dc97201cd
ToppCellNeuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_1(EFTUD1P1)|Neuronal / cells hierarchy compared to all cells using T-Statistic

TTC29 TNIP3 ZFHX3 ROS1 ITPR2

7.39e-062006053d677f13e429abc805a52ec2b8f36c703f511569
ToppCellNeuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_1(EFTUD1P1)--|Neuronal / cells hierarchy compared to all cells using T-Statistic

TTC29 TNIP3 ZFHX3 ROS1 ITPR2

7.39e-0620060512518f4a8d01fc66b72878cdf0ba124b37cff3d8
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN2(Gad1Gad2)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PDC SYCP1 KIF14

3.29e-0546603771bca319a0324b551b1d83bd6eba1e033a12d26
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-7|TCGA-Brain / Sample_Type by Project: Shred V9

PI4K2B BRCA2 KIF14 MAP3K1

3.42e-05136604d94f0fbeb7b80d4cf0687d1924ebf8f9dd07358c
ToppCellCOVID-19_Moderate-multiplets|World / disease group, cell group and cell class

ANKRD36B ANKRD36 ANKRD36C KRT79

5.83e-05156604afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_TBC1D26|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TTC29 TNIP3 ZFHX3 ROS1

6.13e-051586043d6295fe25e3b1fb4b6e83704c5bdbf86dc639b3
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell-DC2_(CD1c+_dendritic_cell)-DC2_L.1.2.1.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BRCA1 MYO5A ZNF782 HSPA6

7.25e-0516560476abebe80e5f8bf44825bb619ae86fcb6f66ffeb
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TNIP3 ZFHX3 ROS1 ITPR2

7.25e-05165604e381bcd558745f3a60346f78b49d0b2672184baa
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TNIP3 ZFHX3 ROS1 ITPR2

7.25e-05165604fee7f2f8d0e25c0d067adc73f8913721bd709a3e
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TTC29 TNIP3 ZFHX3 ROS1

7.59e-05167604a6ff7a3d9b80839c0efa91658836812e868561fa
ToppCell3'-Child09-12-SmallIntestine-Epithelial-Tuft-related-Tuft|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZFHX3 PSTPIP2 EPHA4 ITPR2

7.95e-0516960405e12524d68d409fed386ffad233305683b4575b
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_ETV4|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TTC29 TNIP3 ZFHX3 ROS1

7.95e-05169604ccb7b2daa65cb5f4c1e7a48b3bcdf0cb8f7675c3
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA1 BRCA2 KIF14 CEP128

7.95e-051696040bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_TBC1D26|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TTC29 TNIP3 ZFHX3 ROS1

7.95e-051696042abdd8ae9a5d88aac30992142d1b502c959bc015
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABR CEP70 KIF14 PSTPIP2

8.13e-051706047534ac69ca3a378df78d61c284e89bc96a71a4a8
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

LMNA ANKRD36 ANKRD36C GOLGB1

8.32e-051716042e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_TBC1D26|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TTC29 TNIP3 ZFHX3 ROS1

8.70e-0517360437457ce2b0bb2a56d6e56f6fd9c668eb40c70ae0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA1 BRCA2 KIF14 CEP128

8.90e-0517460484da9faff088d05233183b425385beb054c92d1b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA1 BRCA2 KIF14 CEP128

8.90e-05174604dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TTC29 TNIP3 ZFHX3 ROS1

9.30e-05176604ed421d8525108d2f585265d2cf777f07b29f44f0
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA1 BRCA2 KIF14 CEP128

9.93e-0517960480112c686a8f85ad5e3cda6e3f3d3d51cf688092
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BRCA1 BRCA2 KIF14 CEP128

1.01e-04180604334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA1 BRCA2 KIF14 CEP128

1.01e-04180604f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC29 SCN7A KIF14 CEP128

1.04e-04181604c26d3cbbc592299786d79d1b15fc6bead2aafb9a
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANKRD36B ANKRD36 ANKRD36C GOLGB1

1.10e-0418460401c19a830348ab0b9c02c1546a439de70ee10f97
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA1 BRCA2 KIF14 CEP128

1.13e-0418560430e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

USP8 PBRM1 ZNF184 MAP3K1

1.15e-0418660403db813598b67b1e08f759758a1c2023396921fa
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA1 BRCA2 KIF14 CEP128

1.17e-041876049351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCellMonocytes-M2-like_CD16+_macrophages|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

BRCA2 BAZ2B NEB ITPR2

1.17e-0418760459e31c51183ed4c9a3d0792c8005ea3a12b28dfa
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA1 BRCA2 KIF14 CEP128

1.17e-04187604057569c9437219ecc396aa6e673b1178a2273837
ToppCelldroplet-Marrow-nan-3m-Hematologic-erythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PI4K2B BRCA1 LMNA BRCA2

1.22e-041896048a38baee58a27c2fa3f4bd131ab9f15723ed9295
ToppCellNS-moderate-d_16-33-Epithelial-FOXN4+|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

BRCA1 BRCA2 ZBTB21 CEP128

1.25e-04190604250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SETD2 ANKRD36C GOLGB1 MAP3K1

1.25e-0419060491ba66d4b56c59523485b17738e93f14bb00afa4
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

ZFHX4 ZFHX3 CEP126 EPHA4

1.25e-041906046e92c78799f34b31d098854503c796edb0dc7f80
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA1 BRCA2 KIF14 ANKRD36C

1.25e-0419060431de1727822e9818652946dfb962daee77ffad68
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BRCA1 BRCA2 ANKRD36 ANKRD36C

1.25e-041906040adb24dafa077156bbc73a8d8cbf3d9eeb6e08df
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BRCA1 BRCA2 ANKRD36 ANKRD36C

1.25e-0419060405455775845f4ded5c27e7b83242078d23162aaf
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANKRD36B ANKRD36 ANKRD36C GOLGB1

1.25e-041906043c337374d89e69cc0a78e65a4a7e21db7b050fcd
ToppCellpdx-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

BRCA1 BRCA2 KIF14 CEP128

1.25e-04190604d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANKRD36B ANKRD36 ANKRD36C GOLGB1

1.25e-0419060423f2ac4da431211084bb6ab0494c2e0b69547cb6
ToppCellCOVID-19-kidney-Proliferating_T_cell|COVID-19 / Disease (COVID-19 only), tissue and cell type

BRCA2 KIF14 CEP128 HSPA6

1.27e-04191604bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-ventral_progenitors_and_neurons_2|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

ZFHX4 CFL1 ZFHX3 EPHA4

1.27e-04191604509d17d8ee0d028757ce0f2c9b97e5875f06f0ab
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANKRD36B TNIP3 ANKRD36 ANKRD36C

1.33e-04193604463274f394757fb2570ae885d58e1f9fa7e60c4a
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BRCA1 BRCA2 TNIP3 KIF14

1.33e-04193604444de545117dae8ab24a22880583ac2f0b2d6eac
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

BRCA1 BRCA2 KIF14 CEP128

1.33e-041936044b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYO5A PSTPIP2 HSPA6 ITPR2

1.35e-04194604663e7e7fe48157e808b4f1a0ea6ad41944e857a2
ToppCellwk_20-22-Hematologic_Lymphocytic-B-Pro-B|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

RAG1 BRCA1 BRCA2 KIF14

1.35e-041946043590ff471f74a361ee5bf02a58e3104cd3bf7d00
ToppCell368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

PSTPIP2 HSPA6 ITPR2 ZNF445

1.35e-0419460458046894446cb250814252a23f60fdd59c114d77
ToppCellCOVID-19-T_cells-Cycling_NK/T_cells|COVID-19 / group, cell type (main and fine annotations)

BRCA1 BRCA2 KIF14 CEP128

1.38e-04195604764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

BRCA1 BRCA2 KIF14 CEP128

1.38e-04195604926eb3fc5d028be936885bea0654a77db3107234
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

BRCA1 BRCA2 KIF14 CEP128

1.38e-041956041a5e814e12fe37287dbfc58189e1958e2c76b5da
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

BRCA1 BRCA2 KIF14 CEP128

1.41e-041966041d2e0b328eb822db7521b5f5724d4bd17c0bad5f
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

BRCA1 BRCA2 KIF14 CEP128

1.41e-041966041964c5003a0cb84539850a7cfe3bbb0e23a61d2d
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

BRCA1 BRCA2 KIF14 CEP128

1.41e-0419660473f951f7712e0aa3323676b9a4b7944d21d347c4
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

BRCA1 BRCA2 KIF14 CEP128

1.44e-041976048b616cde333bdbc0c591035ad9e4949155866245
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

BRCA1 BRCA2 KIF14 CEP128

1.44e-0419760484ed777cdba569200a3ef1654d8a12f17fcfb7f1
ToppCellCOVID-19-kidney-Macrophages|COVID-19 / Disease (COVID-19 only), tissue and cell type

ABR PSTPIP2 HSPA6 ITPR2

1.44e-041976043912301018d0863144dcfac8d1fa8adc081748d7
ToppCellproximal-3-Hematologic-Proliferating_Macrophage|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

BRCA1 BRCA2 KIF14 KRT79

1.44e-041976040dd9058aa19d1268ebba9a65555870224b5a5978
ToppCellproximal-Hematologic-Proliferating_Macrophage|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

BRCA1 BRCA2 KIF14 KRT79

1.44e-041976040b1fa881abbfcc54b322fc27124db3f8947af016
ToppCellproximal-Hematologic-Proliferating_Macrophage-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

BRCA1 BRCA2 KIF14 KRT79

1.44e-041976049243617b307acf3df40d93c41cd8d4788699a7ea
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BRCA1 BRCA2 TNIP3 KIF14

1.46e-04198604428182c71f009906c581e02257e545ea5fb99650
ToppCellcritical-Epithelial-FOXN4+|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

BRCA2 ZBTB21 ANKRD36 MYO5C

1.46e-041986046b160b3d6a2c1b1641c2c7dcec1a7ef38411fec9
ToppCelldistal-Hematologic-Proliferating_Macrophage-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

BRCA1 BRCA2 TNIP3 KIF14

1.46e-041986048afeb1f9bc9d8551482c8fefe4c5f88d9cd13ee2
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-35|World / Primary Cells by Cluster

BAZ2B PHF14 ANKRD36 ANKRD36C

1.46e-04198604de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ZNF451 ANKRD36 ANKRD36C GOLGB1

1.49e-04199604f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

BAZ2B ANKRD36 EEA1 GOLGB1

1.49e-04199604c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCellNasal_Brush-Epithelial-Goblet_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

ANKRD36B TNIP3 ANKRD36 ANKRD36C

1.49e-041996042ac716f887687b5109fb9feced75d5c62646a268
ToppCellLPS_IL1RA-Endothelial-Endothelial-FOXM1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

BRCA1 BRCA2 CEP70 KIF14

1.49e-04199604be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCellNasal_Brush-Epithelial-Goblet_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

ANKRD36B TNIP3 ANKRD36 ANKRD36C

1.49e-04199604aa6f1390283617c7f9aaf91d379024832ea24a9e
ToppCellNon-neuronal-Dividing-IPC-IPC-div2|World / Primary Cells by Cluster

BRCA1 ZFHX4 BRCA2 BAZ2B

1.52e-042006044923d7a4f00853c4d76fc1cc0fa82d522a2302e7
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

BRCA1 BRCA2 CEP70 KIF14

1.52e-042006044cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

LMNA EEA1 NEB ITPR2

1.52e-042006045ba4ed490c64b3bb738e7729669f893fa73aa56f
ToppCellNon-neuronal-Dividing-IPC|World / Primary Cells by Cluster

BRCA1 ZFHX4 BRCA2 KIF14

1.52e-04200604971533181daa1bfac1f1b8c507d2013f891f9078
ToppCellNon-neuronal-Dividing-IPC-IPC-div2-5|World / Primary Cells by Cluster

BRCA1 ZFHX4 BRCA2 BAZ2B

1.52e-04200604dc1c1506823eaa105f1532c6b5d4efa14e788314
ToppCellBronchus_Control_(B.)-Epithelial-TX-Club|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

ANKRD36B ANKRD36 ANKRD36C MYO5C

1.52e-04200604292c63693eb7f435335a8cfba07aa35b72139393
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BRCA1 BRCA2 KIF14 CEP128

1.52e-04200604af3dc76b4507bf4edd265169f5dfbbb8a19eb394
ToppCellCOVID-19-Myeloid-MoAM2,_CCL18|Myeloid / Condition, Lineage and Cell class

LMNA MYO5A ZFHX3 ITPR2

1.52e-04200604a60346c5ea7a3dae1ad3c5dc6c6eca65b64c6888
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Intermediate|2m / Sample Type, Dataset, Time_group, and Cell type.

ABR MYO5A BAZ2B PHF14

1.52e-042006042a635694844ddabcd98462c5636a6f41a3f08a46
ToppCellSigmoid-T_cell-cycling_gd_T|T_cell / Region, Cell class and subclass

ZNF594 BRCA1 BRCA2 KIF14

1.52e-042006044e489ecf472857357d45e9f6c7a812aa48b72ebf
ToppCellmild-T/NK_proliferative|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BRCA1 BRCA2 KIF14 ANKRD36C

1.52e-0420060463cc57b9331459efbb73051d174d198a3568b938
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

RIF1 ANKRD36C GOLGB1

7.12e-0450383GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_4
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

BAZ2B GOLGB1 MAP3K1

7.12e-0450383GAVISH_3CA_MALIGNANT_METAPROGRAM_29_NPC_OPC
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

RIF1 SETD2 GOLGB1

7.12e-0450383GAVISH_3CA_MALIGNANT_METAPROGRAM_4_CHROMATIN
ComputationalPorins / transporters.

ADRB2 SCN7A ROS1 EPHA4 ITPR2

8.23e-04211385MODULE_63
Diseaseductal carcinoma in situ (biomarker_via_orthology)

BRCA1 BRCA2

3.80e-062582DOID:0060074 (biomarker_via_orthology)
DiseaseHereditary site-specific ovarian cancer syndrome

BRCA1 BRCA2

3.80e-062582C4749652
Diseasecolorectal cancer (is_marker_for)

SETD2 PBRM1 BRCA1 BRCA2 ZFHX3

1.46e-05157585DOID:9256 (is_marker_for)
DiseaseHereditary breast ovarian cancer syndrome

BRCA1 BRCA2

2.27e-054582cv:C0677776
DiseaseAuriculo-Ventricular Dissociation

CACNA1D LMNA

2.27e-054582C0004331
DiseaseHeart Block

CACNA1D LMNA

2.27e-054582C0018794
Diseaseblood phosphate measurement

USP8 ABR CFL1 ZFHX3 GOLGB1

2.40e-05174585EFO_0010972
DiseaseProstatic Neoplasms

RAG1 SETD2 ADRB2 ABR BRCA1 BRCA2 ZFHX3 MAP3K1

2.64e-05616588C0033578
DiseaseMalignant neoplasm of prostate

RAG1 SETD2 ADRB2 ABR BRCA1 BRCA2 ZFHX3 MAP3K1

2.64e-05616588C0376358
Diseasehereditary breast ovarian cancer syndrome (is_implicated_in)

BRCA1 BRCA2

3.78e-055582DOID:5683 (is_implicated_in)
DiseaseAdult only

BRCA1 BRCA2

5.67e-056582C3842001
DiseaseNeoplasm of uncertain or unknown behavior of breast

PBRM1 BRCA1 BRCA2

7.29e-0541583C0496956
DiseaseBreast adenocarcinoma

PBRM1 BRCA1 BRCA2

7.29e-0541583C0858252
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

BRCA1 BRCA2 MAP3K1

9.64e-0545583DOID:3748 (is_implicated_in)
DiseasePancreatic carcinoma, familial

BRCA1 BRCA2

1.35e-049582C2931038
DiseaseMalignant tumor of prostate

BRCA2 ZFHX3

1.35e-049582cv:C0376358
Diseaselung non-small cell carcinoma (is_implicated_in)

PBRM1 BRCA1 ZFHX3 MAP3K1

1.64e-04139584DOID:3908 (is_implicated_in)
DiseaseFanconi anemia (is_implicated_in)

BRCA1 BRCA2

1.69e-0410582DOID:13636 (is_implicated_in)
Diseasecognitive behavioural therapy

SCN7A ZFHX3 NEB

2.06e-0458583EFO_0007820
DiseaseBenign tumor of pancreas

BRCA1 BRCA2

2.92e-0413582C0347284
DiseaseHereditary Breast and Ovarian Cancer Syndrome

BRCA1 BRCA2

3.40e-0414582C0677776
DiseasePancreatic carcinoma

BRCA1 BRCA2

6.36e-0419582C0235974
DiseaseBreast Carcinoma

SETD2 PBRM1 BRCA1 BRCA2 CFL1 MAP3K1

6.48e-04538586C0678222
Diseaseblood aluminium measurement

BAZ2B EPHA4

7.05e-0420582EFO_0007575
DiseaseAdenocarcinoma of prostate

BRCA1 BRCA2

7.05e-0420582C0007112
DiseaseBREAST CANCER

BRCA1 BRCA2

7.78e-0421582114480
DiseasePancreatic Neoplasm

BRCA1 BRCA2 SYCP1

1.02e-03100583C0030297
DiseaseNeoplasm of the genitourinary tract

BRCA2 ZFHX3

1.02e-0324582cv:C0042065
DiseaseMalignant neoplasm of pancreas

BRCA1 BRCA2 SYCP1

1.08e-03102583C0346647
DiseaseFanconi Anemia

BRCA1 BRCA2

1.11e-0325582C0015625
Diseasebreast cancer (implicated_via_orthology)

BRCA1 BRCA2

1.11e-0325582DOID:1612 (implicated_via_orthology)
DiseaseMalignant neoplasm of breast

RIF1 SETD2 PBRM1 BRCA1 BRCA2 CFL1 GOLGB1 MAP3K1

1.14e-031074588C0006142
DiseaseMalignant tumor of breast

BRCA1 BRCA2

1.29e-0327582cv:C0006142
DiseaseBreast neoplasm

BRCA1 BRCA2

1.29e-0327582cv:C1458155
DiseaseFamilial cancer of breast

BRCA1 BRCA2

1.29e-0327582cv:C0346153
DiseaseMiller Dieker syndrome

BRCA1 BRCA2

1.49e-0329582C0265219
DiseaseNeoplasm of uncertain or unknown behavior of ovary

BRCA1 BRCA2

1.49e-0329582C0496920
DiseaseOvarian Carcinoma

BRCA1 BRCA2

1.59e-0330582C0029925
DiseaseBreast Cancer, Familial

BRCA1 BRCA2

1.59e-0330582C0346153
Diseaseprostate cancer (is_implicated_in)

BRCA1 BRCA2 ZFHX3

1.60e-03117583DOID:10283 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
EKCYDKTKVNKDNNE

ABR

571

Q12979
SKLFEDDEHEKEQYC

AKAP2

191

Q9Y2D5
YHVEQEKENKLLCED

ADRB2

366

P07550
KYQCLKDQLEEREKH

CEP128

781

Q6ZU80
IKHELQANCYEEVKD

CFL1

131

P23528
TDHCEQKEDLKEKDN

BAZ2B

1441

Q9UIF8
VNELNHSKEKECQYE

ANKRD36

1781

A6QL64
HSKEKECQYEKEKAE

ANKRD36

1786

A6QL64
ELNHSKEKECQYEKE

ANKRD36B

1221

Q8N2N9
ENKHYEVAKKCVEDL

RC3H2

91

Q9HBD1
KECNEEVSLEKYNHH

RAG1

361

P15918
NCQEVHDLLKDYDLK

RAVER2

81

Q9HCJ3
KKNYEQKCRDKDEAE

PSTPIP2

141

Q9H939
EQEKFLTCDEYEKKQ

ITPR2

246

Q14571
ELNHSKEKKCQYEKE

ANKRD36C

1646

Q5JPF3
EVYNEKIHDLLVCKD

KIF14

496

Q15058
KLKNQEYETLDHLEC

PBRM1

436

Q86U86
QHEDQVEQYKKELEK

LMNA

251

P02545
KNKYEDEINKHTAAE

KRT79

231

Q5XKE5
YSKAKQEADEEKHLN

EPHA4

576

P54764
DEDSKKHFNYNKIVE

ESF1

716

Q9H501
EYELIHKEKEDENCL

PDC

76

P20941
QDIVKYHVKCDNEEI

PDE6A

451

P16499
HKEYEDEIDCLQKEV

OBI1

96

Q5W0B1
KLENEQEKLHVEYNK

PHF14

646

O94880
LVRYEKQKCEKEIDH

PI4K2B

311

Q8TCG2
SNCKHPEIKKQEYEE

BRCA1

1101

P38398
QEHCSQLESHLKEYK

EEA1

701

Q15075
DTHQEYARVKEECLK

ICE1

111

Q9Y2F5
KIFHEANADECEKSK

BRCA2

331

P51587
VKCQHYKKKRTEQEE

CEP70

156

Q8NHQ1
KEEEIKYFNCNKEEL

CEP126

501

Q9P2H0
QLENEKRKYDEHVKS

CCDC30

451

Q5VVM6
KEYEHNKRLQDFKDC

CEP95

631

Q96GE4
DNLYKKVDKHLCEEE

EXOC1

826

Q9NV70
KEEYEHQKRELEQIC

HSPA6

591

P17066
DKCKKEFDEDVYNHK

ELP4

136

Q96EB1
QEQGEKEYKNCELDK

CACNA1D

1156

Q01668
TYKDDVNHNQKCKEK

MAP3K1

1166

Q13233
KQECIKAENQSHDYK

RIF1

1591

Q5UIP0
DLDVQKKLYDCLEEH

ACD

141

Q96AP0
TDENIKRKDHIDYQK

ZNF451

61

Q9Y4E5
HKEKSDEEEQQYVIK

ZNF451

776

Q9Y4E5
DLITHQKKQCYKDED

ZFHX4

2281

Q86UP3
ELKQEHESKCEYKKL

ZBTB21

761

Q9ULJ3
QCKFDHDAELEKRKE

ZC3H6

291

P61129
TLANKEKEHYECEIK

TNIP3

146

Q96KP6
EKEHYECEIKRLNKA

TNIP3

151

Q96KP6
QHLEQEYKKEINDKE

SYCP1

251

Q15431
EKEPHADKDFCQEKQ

ROS1

2306

P08922
ECNENVKHKTKEYIK

SETD2

2531

Q9BYW2
LHEEEKFYKQDECRE

ZNF445

646

P59923
EKIHNERKSYECKEC

ZNF790

441

Q6PG37
KEKDDIDHYLEVNFK

TTC29

36

Q8NA56
HNINKTYECKECEKT

ZNF594

121

Q96JF6
KNYEEFVCHIDKDCQ

SCN7A

651

Q01118
QYSKEKAHERNVCDK

ZNF782

156

Q6ZMW2
KRYKEENNDHLDDFK

USP8

891

P40818
QKTHTQEKAYECKEC

ZNF184

521

Q99676
HQKKLCYKDEDEEGQ

ZFHX3

2346

Q15911
HKAQEIYEKNLDEKA

GOLGB1

701

Q14789
EVEEDKENKEYSEKC

GOLGB1

1036

Q14789
KKCIEEHADRYKQET

MYO5A

1006

Q9Y4I1
LESHFQSQKDCYEKE

MYO5C

1151

Q9NQX4
CNDVQSELKYKAEHV

NEB

4241

P20929