Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	5-diphosphoinositol pentakisphosphate 1-kinase activity	PPIP5K1 PPIP5K2	1.96e-05	2	89	2	GO:0033857
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	CHD5 CHD9 CHD8 CHD6	2.18e-05	37	89	4	GO:0140658
GeneOntologyMolecularFunction	GABA-gated chloride ion channel activity	GABRB1 GABRB2 GABRB3	6.65e-05	18	89	3	GO:0022851
GeneOntologyMolecularFunction	GABA-A receptor activity	GABRB1 GABRB2 GABRB3	7.88e-05	19	89	3	GO:0004890
GeneOntologyMolecularFunction	inositol hexakisphosphate 3-kinase activity	PPIP5K1 PPIP5K2	1.17e-04	4	89	2	GO:0052724
GeneOntologyMolecularFunction	inositol hexakisphosphate 1-kinase activity	PPIP5K1 PPIP5K2	1.17e-04	4	89	2	GO:0052723
GeneOntologyMolecularFunction	GABA receptor activity	GABRB1 GABRB2 GABRB3	1.24e-04	22	89	3	GO:0016917
GeneOntologyMolecularFunction	diphosphoinositol pentakisphosphate kinase activity	PPIP5K1 PPIP5K2	1.95e-04	5	89	2	GO:0000829
GeneOntologyMolecularFunction	inositol hexakisphosphate kinase activity	PPIP5K1 PPIP5K2	1.95e-04	5	89	2	GO:0000828
GeneOntologyMolecularFunction	inositol-1,3,4,5,6-pentakisphosphate kinase activity	PPIP5K1 PPIP5K2	1.95e-04	5	89	2	GO:0000827
GeneOntologyMolecularFunction	inositol hexakisphosphate 5-kinase activity	PPIP5K1 PPIP5K2	1.95e-04	5	89	2	GO:0000832
GeneOntologyMolecularFunction	helicase activity	CHD5 DDX42 CHD9 CHD8 CHD6	7.08e-04	158	89	5	GO:0004386
GeneOntologyMolecularFunction	inositol phosphate kinase activity	PPIP5K1 PPIP5K2	1.05e-03	11	89	2	GO:0180030
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	CHD5 CHD9 CHD8 CHD6 PTBP1 MGME1	1.13e-03	262	89	6	GO:0140097
GeneOntologyMolecularFunction	ligand-gated monoatomic anion channel activity	GABRB1 GABRB2 GABRB3	1.44e-03	50	89	3	GO:0099095
GeneOntologyMolecularFunction	cysteine-type deubiquitinase activity	OTUD5 USP24 DESI2 USP9Y	1.69e-03	114	89	4	GO:0004843
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	GABRB1 GABRB2 GABRB3	2.10e-03	57	89	3	GO:1904315
GeneOntologyMolecularFunction	K63-linked deubiquitinase activity	OTUD5 DESI2	2.26e-03	16	89	2	GO:0061578
GeneOntologyMolecularFunction	deubiquitinase activity	OTUD5 USP24 DESI2 USP9Y	2.30e-03	124	89	4	GO:0101005
GeneOntologyMolecularFunction	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	GABRB1 GABRB2 GABRB3	2.44e-03	60	89	3	GO:0099529
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	CHD5 CHD9 CHD8 CHD6	2.51e-03	127	89	4	GO:0008094
GeneOntologyMolecularFunction	quinone binding	COQ10A NDUFS2	2.56e-03	17	89	2	GO:0048038
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine phosphatase activity	PTPRA PTPRE	2.56e-03	17	89	2	GO:0005001
GeneOntologyMolecularFunction	transmembrane receptor protein phosphatase activity	PTPRA PTPRE	2.56e-03	17	89	2	GO:0019198
GeneOntologyMolecularFunction	transmitter-gated channel activity	GABRB1 GABRB2 GABRB3	3.06e-03	65	89	3	GO:0022835
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity	GABRB1 GABRB2 GABRB3	3.06e-03	65	89	3	GO:0022824
GeneOntologyBiologicalProcess	cellular response to histamine	GABRB1 GABRB2 GABRB3	2.59e-06	7	88	3	GO:0071420
GeneOntologyBiologicalProcess	response to histamine	GABRB1 GABRB2 GABRB3	1.61e-05	12	88	3	GO:0034776
GeneOntologyCellularComponent	GABA-A receptor complex	GABRB1 GABRB2 GABRB3	6.65e-05	19	88	3	GO:1902711
GeneOntologyCellularComponent	GABA receptor complex	GABRB1 GABRB2 GABRB3	9.08e-05	21	88	3	GO:1902710
GeneOntologyCellularComponent	postsynaptic specialization membrane	GABRB1 GABRB2 GABRB3 KCNH1 CNIH2 CNKSR2	2.07e-04	201	88	6	GO:0099634
MousePheno	abnormal social investigation	GABRB3 CUL3 CREBRF ARID1B UBE3A SRC CHD8 ADCY3	2.35e-06	171	71	8	MP:0001360
MousePheno	decreased dentate gyrus size	CUL3 ARID1B ADCY3	6.90e-06	8	71	3	MP:0012460
MousePheno	abnormal learning/memory/conditioning	GABRB1 GABRB2 GABRB3 DOCK3 RALGAPA1 ARID1B KLHL1 PTPRA UBE3A NACC1 CNIH2 SRC PRKCB ZC3H12B CHD8 CNKSR2 ADCY3 MYBPC3	3.32e-05	1239	71	18	MP:0002063
MousePheno	abnormal cognition	GABRB1 GABRB2 GABRB3 DOCK3 RALGAPA1 ARID1B KLHL1 PTPRA UBE3A NACC1 CNIH2 SRC PRKCB ZC3H12B CHD8 CNKSR2 ADCY3 MYBPC3	3.58e-05	1246	71	18	MP:0014114
MousePheno	abnormal response to social novelty	GABRB3 CUL3 ARID1B SRC	1.09e-04	49	71	4	MP:0020395
Domain	GABAAb_rcpt	GABRB1 GABRB2 GABRB3	9.76e-08	3	87	3	IPR002289
Domain	BRK	CHD9 CHD8 CHD6	1.93e-06	6	87	3	SM00592
Domain	BRK_domain	CHD9 CHD8 CHD6	1.93e-06	6	87	3	IPR006576
Domain	BRK	CHD9 CHD8 CHD6	1.93e-06	6	87	3	PF07533
Domain	Chromo_domain	CHD5 CHD9 CHD8 CHD6	4.35e-06	24	87	4	IPR023780
Domain	Chromo	CHD5 CHD9 CHD8 CHD6	6.07e-06	26	87	4	PF00385
Domain	CHROMO_1	CHD5 CHD9 CHD8 CHD6	8.26e-06	28	87	4	PS00598
Domain	CHROMO_2	CHD5 CHD9 CHD8 CHD6	8.26e-06	28	87	4	PS50013
Domain	SNF2_N	CHD5 CHD9 CHD8 CHD6	1.43e-05	32	87	4	IPR000330
Domain	Chromodomain-like	CHD5 CHD9 CHD8 CHD6	1.43e-05	32	87	4	IPR016197
Domain	SNF2_N	CHD5 CHD9 CHD8 CHD6	1.43e-05	32	87	4	PF00176
Domain	Chromo/shadow_dom	CHD5 CHD9 CHD8 CHD6	1.62e-05	33	87	4	IPR000953
Domain	CHROMO	CHD5 CHD9 CHD8 CHD6	1.62e-05	33	87	4	SM00298
Domain	K_chnl_volt-dep_EAG	KCNH1 KCNH5	2.14e-05	2	87	2	IPR003949
Domain	Tyr_Pase_rcpt_a/e-type	PTPRA PTPRE	2.14e-05	2	87	2	IPR016336
Domain	ARM-type_fold	DOCK3 RALGAPA1 KIFAP3 STAG1 XPO6 PKP4 USP24 APOB USP9Y	2.84e-05	339	87	9	IPR016024
Domain	Helicase_C	CHD5 DDX42 CHD9 CHD8 CHD6	1.43e-04	107	87	5	PF00271
Domain	HELICc	CHD5 DDX42 CHD9 CHD8 CHD6	1.43e-04	107	87	5	SM00490
Domain	Helicase_C	CHD5 DDX42 CHD9 CHD8 CHD6	1.49e-04	108	87	5	IPR001650
Domain	HELICASE_CTER	CHD5 DDX42 CHD9 CHD8 CHD6	1.56e-04	109	87	5	PS51194
Domain	HELICASE_ATP_BIND_1	CHD5 DDX42 CHD9 CHD8 CHD6	1.56e-04	109	87	5	PS51192
Domain	DEXDc	CHD5 DDX42 CHD9 CHD8 CHD6	1.56e-04	109	87	5	SM00487
Domain	GABAA/Glycine_rcpt	GABRB1 GABRB2 GABRB3	1.62e-04	23	87	3	IPR006028
Domain	Helicase_ATP-bd	CHD5 DDX42 CHD9 CHD8 CHD6	1.63e-04	110	87	5	IPR014001
Domain	Acid_Pase_AS	PPIP5K1 PPIP5K2	3.18e-04	6	87	2	IPR033379
Domain	-	TTC8 KIFBP CFAP70 TEX11 TTK KDM6A	4.13e-04	207	87	6	1.25.40.10
Domain	HIS_ACID_PHOSPHAT_2	PPIP5K1 PPIP5K2	4.44e-04	7	87	2	PS00778
Domain	HIS_ACID_PHOSPHAT_1	PPIP5K1 PPIP5K2	4.44e-04	7	87	2	PS00616
Domain	DNA/RNA_helicase_DEAH_CS	CHD5 CHD8 CHD6	5.74e-04	35	87	3	IPR002464
Domain	His_Pase_clade-2	PPIP5K1 PPIP5K2	5.90e-04	8	87	2	IPR000560
Domain	His_Phos_2	PPIP5K1 PPIP5K2	5.90e-04	8	87	2	PF00328
Domain	DEAH_ATP_HELICASE	CHD5 CHD8 CHD6	7.32e-04	38	87	3	PS00690
Domain	TPR-like_helical_dom	TTC8 KIFBP CFAP70 TEX11 TTK KDM6A	7.69e-04	233	87	6	IPR011990
Domain	PAS_9	KCNH1 KCNH5	9.42e-04	10	87	2	PF13426
Domain	Neurotransmitter_ion_chnl_CS	GABRB1 GABRB2 GABRB3	1.20e-03	45	87	3	IPR018000
Domain	Neur_chan_memb	GABRB1 GABRB2 GABRB3	1.28e-03	46	87	3	PF02932
Domain	Neur_chan_LBD	GABRB1 GABRB2 GABRB3	1.37e-03	47	87	3	PF02931
Domain	NEUROTR_ION_CHANNEL	GABRB1 GABRB2 GABRB3	1.37e-03	47	87	3	PS00236
Domain	Neurotrans-gated_channel_TM	GABRB1 GABRB2 GABRB3	1.37e-03	47	87	3	IPR006029
Domain	-	GABRB1 GABRB2 GABRB3	1.37e-03	47	87	3	2.70.170.10
Domain	Neur_channel	GABRB1 GABRB2 GABRB3	1.37e-03	47	87	3	IPR006201
Domain	Neur_chan_lig-bd	GABRB1 GABRB2 GABRB3	1.37e-03	47	87	3	IPR006202
Domain	ARM-like	KIFAP3 ARID1B STAG1 XPO6 PKP4 USP9Y	1.64e-03	270	87	6	IPR011989
Domain	K_chnl_volt-dep_EAG/ELK/ERG	KCNH1 KCNH5	1.88e-03	14	87	2	IPR003938
Domain	TPR	TTC8 CFAP70 TEX11 KDM6A	3.11e-03	129	87	4	SM00028
Domain	TPR_repeat	TTC8 CFAP70 TEX11 KDM6A	3.47e-03	133	87	4	IPR019734
Domain	His_PPase_superfam	PPIP5K1 PPIP5K2	3.86e-03	20	87	2	IPR029033
Domain	-	PPIP5K1 PPIP5K2	3.86e-03	20	87	2	3.40.50.1240
Pubmed	GABAA receptor beta 1, beta 2, and beta 3 subunits: comparisons in DBA/2J and C57BL/6J mice.	GABRB1 GABRB2 GABRB3	1.62e-08	3	89	3	7893750
Pubmed	Expression and distribution of GABAA receptor subtypes in human alcoholic cerebral cortex.	GABRB1 GABRB2 GABRB3	1.62e-08	3	89	3	11085308
Pubmed	GABAA receptor beta subunit mRNA expression in the human alcoholic brain.	GABRB1 GABRB2 GABRB3	1.62e-08	3	89	3	15337300
Pubmed	Differential expression of GABAA/benzodiazepine receptor beta 1, beta 2, and beta 3 subunit mRNAs in the developing mouse cerebellum.	GABRB1 GABRB2 GABRB3	1.62e-08	3	89	3	1282920
Pubmed	Identification of the cAMP-dependent protein kinase and protein kinase C phosphorylation sites within the major intracellular domains of the beta 1, gamma 2S, and gamma 2L subunits of the gamma-aminobutyric acid type A receptor.	GABRB1 GABRB2 PRKCB	1.61e-07	5	89	3	1321150
Pubmed	The brefeldin A-inhibited GDP/GTP exchange factor 2, a protein involved in vesicular trafficking, interacts with the beta subunits of the GABA receptors.	GABRB1 GABRB2 GABRB3	1.61e-07	5	89	3	15198677
Pubmed	Evolution of GABA(A) receptor diversity in the human genome.	GABRB1 GABRB2 GABRB3	3.22e-07	6	89	3	10023064
Pubmed	The GABAA Receptor β Subunit Is Required for Inhibitory Transmission.	GABRB1 GABRB2 GABRB3	3.22e-07	6	89	3	29706582
Pubmed	Lamina-specific alterations in cortical GABA(A) receptor subunit expression in schizophrenia.	GABRB1 GABRB2 GABRB3	5.63e-07	7	89	3	20843900
Pubmed	GABA(A) receptor cell surface number and subunit stability are regulated by the ubiquitin-like protein Plic-1.	GABRB1 GABRB2 GABRB3	8.99e-07	8	89	3	11528422
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	NOP58 STAG1 NACC1 CHD5 CHD9 PHF14 ELF2 CHD8 TIMELESS CHD6	3.65e-06	608	89	10	36089195
Pubmed	The biochemical anatomy of cortical inhibitory synapses.	GABRB1 GABRB2 GABRB3	5.78e-06	14	89	3	22768092
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CUL3 KIF13B KIFBP UBE3A NACC1 PABPC3 PKP4 SYNE2 SRC PRKCB CHD8 CNKSR2	6.36e-06	963	89	12	28671696
Pubmed	The Emerging Role of the RBM20 and PTBP1 Ribonucleoproteins in Heart Development and Cardiovascular Diseases.	PTBP1 RBM20	6.48e-06	2	89	2	32276354
Pubmed	Increased PTPRA expression leads to poor prognosis through c-Src activation and G1 phase progression in squamous cell lung cancer.	PTPRA SRC	6.48e-06	2	89	2	28656243
Pubmed	GABAA receptors involved in sleep and anaesthesia: β1- versus β3-containing assemblies.	GABRB1 GABRB3	6.48e-06	2	89	2	21735059
Pubmed	The receptor-like protein-tyrosine phosphatase, RPTP alpha, is phosphorylated by protein kinase C on two serines close to the inner face of the plasma membrane.	PTPRA PRKCB	6.48e-06	2	89	2	7537734
Pubmed	Structural analysis and detection of biological inositol pyrophosphates reveal that the family of VIP/diphosphoinositol pentakisphosphate kinases are 1/3-kinases.	PPIP5K1 PPIP5K2	6.48e-06	2	89	2	18981179
Pubmed	Epileptic encephalopathy de novo GABRB mutations impair γ-aminobutyric acid type A receptor function.	GABRB1 GABRB3	6.48e-06	2	89	2	26950270
Pubmed	β-cell proliferation is associated with increased A-type γ-aminobutyric acid receptor expression in pancreatectomized mice.	GABRB2 GABRB3	6.48e-06	2	89	2	23486367
Pubmed	Protein tyrosine phosphatase alpha inhibits hypothalamic leptin receptor signaling and regulates body weight in vivo.	PTPRA PTPRE	6.48e-06	2	89	2	30615487
Pubmed	Multiple modes for conferring surface expression of homomeric beta1 GABAA receptors.	GABRB1 GABRB3	6.48e-06	2	89	2	18650446
Pubmed	PKC and PTPα participate in Src activation by 1α,25OH2 vitamin D3 in C2C12 skeletal muscle cells.	PTPRA SRC	6.48e-06	2	89	2	21459125
Pubmed	Catalytically active membrane-distal phosphatase domain of receptor protein-tyrosine phosphatase alpha is required for Src activation.	PTPRA SRC	6.48e-06	2	89	2	20158519
Pubmed	Lifelong restructuring of 3D genome architecture in cerebellar granule cells.	ARID1B CHD8	6.48e-06	2	89	2	37676945
Pubmed	Functional distinction of human EAG1 and EAG2 potassium channels.	KCNH1 KCNH5	6.48e-06	2	89	2	11943152
Pubmed	In vivo modeling of myosin binding protein C familial hypertrophic cardiomyopathy.	DES MYBPC3	6.48e-06	2	89	2	10532952
Pubmed	No ligand binding in the GB2 subunit of the GABA(B) receptor is required for activation and allosteric interaction between the subunits.	GABRB1 GABRB2	6.48e-06	2	89	2	12196556
Pubmed	Estrous cycle variations in GABA(A) receptor phosphorylation enable rapid modulation by anabolic androgenic steroids in the medial preoptic area.	GABRB2 GABRB3	6.48e-06	2	89	2	22989919
Pubmed	Tyrosine phosphatase epsilonM stimulates migration and survival of porcine aortic endothelial cells by activating c-Src.	PTPRE SRC	6.48e-06	2	89	2	15522235
Pubmed	Purification, sequencing, and molecular identification of a mammalian PP-InsP5 kinase that is activated when cells are exposed to hyperosmotic stress.	PPIP5K1 PPIP5K2	6.48e-06	2	89	2	17702752
Pubmed	Epigenetic overlap in autism-spectrum neurodevelopmental disorders: MECP2 deficiency causes reduced expression of UBE3A and GABRB3.	GABRB3 UBE3A	6.48e-06	2	89	2	15615769
Pubmed	GABAB1 and GABAB2 receptor subunits co-expressed in cultured human RPE cells regulate intracellular Ca2+ via Gi/o-protein and phospholipase C pathways.	GABRB1 GABRB2	6.48e-06	2	89	2	25241062
Pubmed	Roles of surface residues of intracellular domains of heag potassium channels.	KCNH1 KCNH5	6.48e-06	2	89	2	19172261
Pubmed	Protein tyrosine phosphatases ε and α perform nonredundant roles in osteoclasts.	PTPRA PTPRE	6.48e-06	2	89	2	24694598
Pubmed	Receptor protein tyrosine phosphatase alpha activates pp60c-src and is involved in neuronal differentiation.	PTPRA SRC	6.48e-06	2	89	2	7691597
Pubmed	Tyrosine phosphatases epsilon and alpha perform specific and overlapping functions in regulation of voltage-gated potassium channels in Schwann cells.	PTPRA PTPRE	6.48e-06	2	89	2	16870705
Pubmed	Sedation and anesthesia mediated by distinct GABA(A) receptor isoforms.	GABRB2 GABRB3	6.48e-06	2	89	2	13679430
Pubmed	Increased expression of GABA(A) receptor beta-subunits in the hippocampus of patients with temporal lobe epilepsy.	GABRB2 GABRB3	6.48e-06	2	89	2	14503638
Pubmed	A phosphotyrosine displacement mechanism for activation of Src by PTPalpha.	PTPRA SRC	6.48e-06	2	89	2	10698938
Pubmed	The Significance of the Bifunctional Kinase/Phosphatase Activities of Diphosphoinositol Pentakisphosphate Kinases (PPIP5Ks) for Coupling Inositol Pyrophosphate Cell Signaling to Cellular Phosphate Homeostasis.	PPIP5K1 PPIP5K2	6.48e-06	2	89	2	28126903
Pubmed	Arid1b Haploinsufficiency Causes Abnormal Brain Gene Expression and Autism-Related Behaviors in Mice.	ARID1B CHD8	6.48e-06	2	89	2	28867767
Pubmed	Src kinase regulation by phosphorylation and dephosphorylation.	PTPRE SRC	6.48e-06	2	89	2	15845350
Pubmed	Direct binding of GABAA receptor β2 and β3 subunits to gephyrin.	GABRB2 GABRB3	6.48e-06	2	89	2	23205938
Pubmed	Cloning and characterization of two human VIP1-like inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinases.	PPIP5K1 PPIP5K2	6.48e-06	2	89	2	17690096
Pubmed	Regulation of an ERG K+ current by Src tyrosine kinase.	KCNH1 SRC	6.48e-06	2	89	2	11834728
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	DOCK3 XPO6 CHD9 PPIP5K1 N4BP3	7.38e-06	104	89	5	9205841
Pubmed	Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype.	GABRB1 GABRB2 GABRB3	1.29e-05	18	89	3	19078961
Pubmed	GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality.	GABRB1 GABRB2 GABRB3	1.29e-05	18	89	3	18985723
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	CREBRF KIF13B DES STAG1 PABPC3 CHD5 SYNE2 DDX42 PHF14 APOB CAGE1 CHD6 PTBP1 PPIP5K2	1.73e-05	1442	89	14	35575683
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	CUL3 ARID1B KLHL1 PTPRA PTPRE KCNH1 SRC USP24 PRKCB KCNH5	1.79e-05	730	89	10	34857952
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	KIFBP STAG1 XPO6 DDX42 USP24 SRP54 CHD8 PTBP1 TTK	1.87e-05	582	89	9	20467437
Pubmed	Transgenic overexpression of furin increases epileptic susceptibility.	GABRB2 GABRB3	1.94e-05	3	89	2	30333479
Pubmed	Molecular basis of titin exon exclusion by RBM20 and the novel titin splice regulator PTB4.	PTBP1 RBM20	1.94e-05	3	89	2	29518215
Pubmed	RNA-binding proteins RBM20 and PTBP1 regulate the alternative splicing of FHOD3.	PTBP1 RBM20	1.94e-05	3	89	2	30468920
Pubmed	PPIP5K2 and PCSK1 are Candidate Genetic Contributors to Familial Keratoconus.	PPIP5K1 PPIP5K2	1.94e-05	3	89	2	31852976
Pubmed	The E3 ubiquitin ligase Asb2β is downregulated in a mouse model of hypertrophic cardiomyopathy and targets desmin for proteasomal degradation.	DES MYBPC3	1.94e-05	3	89	2	26343497
Pubmed	Protrudin modulates seizure activity through GABAA receptor regulation.	GABRB2 GABRB3	1.94e-05	3	89	2	31772151
Pubmed	ERα phosphorylation at Y537 by Src triggers E6-AP-ERα binding, ERα ubiquitylation, promoter occupancy, and target gene expression.	UBE3A SRC	1.94e-05	3	89	2	22865929
Pubmed	Altered ultrasonic vocalization and impaired learning and memory in Angelman syndrome mouse model with a large maternal deletion from Ube3a to Gabrb3.	GABRB3 UBE3A	1.94e-05	3	89	2	20808828
Pubmed	N-Glycosylation of GABAA receptor subunits is altered in Schizophrenia.	GABRB1 GABRB2	1.94e-05	3	89	2	23917429
Pubmed	Identification of p130cas as an in vivo substrate of receptor protein-tyrosine phosphatase alpha.	PTPRA SRC	1.94e-05	3	89	2	10787408
Pubmed	Histamine action on vertebrate GABAA receptors: direct channel gating and potentiation of GABA responses.	GABRB1 GABRB3	1.94e-05	3	89	2	18281286
Pubmed	The ATP-dependent chromatin remodeling enzymes CHD6, CHD7, and CHD8 exhibit distinct nucleosome binding and remodeling activities.	CHD8 CHD6	1.94e-05	3	89	2	28533432
Pubmed	SMAP, an Smg GDS-associating protein having arm repeats and phosphorylated by Src tyrosine kinase.	KIFAP3 SRC	1.94e-05	3	89	2	8900189
Pubmed	Beyond Epilepsy and Autism: Disruption of GABRB3 Causes Ocular Hypopigmentation.	GABRB3 UBE3A	1.94e-05	3	89	2	28009282
Pubmed	Phosphorylation-dependent regulation of Kv2.1 Channel activity at tyrosine 124 by Src and by protein-tyrosine phosphatase epsilon.	PTPRE SRC	1.94e-05	3	89	2	12615930
Pubmed	Protein kinase C delta induces Src kinase activity via activation of the protein tyrosine phosphatase PTP alpha.	PTPRA SRC	1.94e-05	3	89	2	12826681
Pubmed	Protein-tyrosine phosphatase-alpha and Src functionally link focal adhesions to the endoplasmic reticulum to mediate interleukin-1-induced Ca2+ signaling.	PTPRA SRC	1.94e-05	3	89	2	19497848
Pubmed	Serine dephosphorylation of receptor protein tyrosine phosphatase alpha in mitosis induces Src binding and activation.	PTPRA SRC	1.94e-05	3	89	2	20385765
Pubmed	Tyrosine phosphatase-epsilon activates Src and supports the transformed phenotype of Neu-induced mammary tumor cells.	PTPRA PTPRE	1.94e-05	3	89	2	12598528
Pubmed	Protein-tyrosine phosphatase alpha acts as an upstream regulator of Fyn signaling to promote oligodendrocyte differentiation and myelination.	PTPRA PTPRE	1.94e-05	3	89	2	19812040
Pubmed	Early growth response 1 (Egr-1) directly regulates GABAA receptor α2, α4, and θ subunits in the hippocampus.	GABRB1 GABRB2 GABRB3	2.08e-05	21	89	3	25708312
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	XPO6 CHD5 SYNE2 PCNX1 CHD8 CHD6	2.55e-05	225	89	6	12168954
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	NOP58 PTPRA CYP3A5 UBE3A OTUD5 NACC1 NR5A2 PHF14 ELF2 CHD8 SLC25A28 TTK NDUFS2	3.25e-05	1327	89	13	32694731
Pubmed	Genome-wide association of lipid-lowering response to statins in combined study populations.	KIF13B APOB ARHGEF16 KLKB1	3.61e-05	72	89	4	20339536
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	ARID1B CTNNAL1 UBE3A NACC1 SYNE2 USP24 CHD6 KDM6A NDUFS2	3.83e-05	638	89	9	31182584
Pubmed	Regulation of hERG and hEAG channels by Src and by SHP-1 tyrosine phosphatase via an ITIM region in the cyclic nucleotide binding domain.	KCNH1 SRC	3.87e-05	4	89	2	24587194
Pubmed	Differential cell surface expression of GABAA receptor alpha1, alpha6, beta2 and beta3 subunits in cultured mouse cerebellar granule cells influence of cAMP-activated signalling.	GABRB2 GABRB3	3.87e-05	4	89	2	11902122
Pubmed	Phosphorylation of receptor protein-tyrosine phosphatase alpha on Tyr789, a binding site for the SH3-SH2-SH3 adaptor protein GRB-2 in vivo.	PTPRA SRC	3.87e-05	4	89	2	7518772
Pubmed	Src kinase activity is regulated by the SHP-1 protein-tyrosine phosphatase.	PTPRA SRC	3.87e-05	4	89	2	9261115
Pubmed	A novel ATPase on mouse chromosome 7 is a candidate gene for increased body fat.	GABRB3 UBE3A	3.87e-05	4	89	2	11074018
Pubmed	Differential assembly diversifies GABAA receptor structures and signalling.	GABRB2 GABRB3	3.87e-05	4	89	2	35355020
Pubmed	Inhibitory synapse formation in a co-culture model incorporating GABAergic medium spiny neurons and HEK293 cells stably expressing GABAA receptors.	GABRB2 GABRB3	3.87e-05	4	89	2	25489750
Pubmed	Expression of tetraspan protein CD63 activates protein-tyrosine kinase (PTK) and enhances the PTK-induced inhibition of ROMK channels.	PTPRA SRC	3.87e-05	4	89	2	18211905
Pubmed	GABAA Receptors and the Diversity in their Structure and Pharmacology.	GABRB2 GABRB3	3.87e-05	4	89	2	28528665
Pubmed	Regulatory effects of nitric oxide on Src kinase, FAK, p130Cas, and receptor protein tyrosine phosphatase alpha (PTP-alpha): a role for the cellular redox environment.	PTPRA SRC	3.87e-05	4	89	2	20055753
Pubmed	Activation of Src and transformation by an RPTPα splice mutant found in human tumours.	PTPRA SRC	3.87e-05	4	89	2	21725282
Pubmed	Deletion and expression analysis of AZFa genes on the human Y chromosome revealed a major role for DBY in male infertility.	USP9Y KDM6A	3.87e-05	4	89	2	10767340
Pubmed	Mechanistic insights of NAC1 nuclear export and its role in ovarian cancer resistance to docetaxel.	CUL3 NACC1	3.87e-05	4	89	2	37019189
Pubmed	Mitotic activation of protein-tyrosine phosphatase alpha and regulation of its Src-mediated transforming activity by its sites of protein kinase C phosphorylation.	PTPRA SRC	3.87e-05	4	89	2	11923305
Pubmed	NAC1 regulates the recruitment of the proteasome complex into dendritic spines.	CUL3 NACC1	6.44e-05	5	89	2	17699672
Pubmed	Differential expression of GABAA/benzodiazepine receptor subunit mRNAs and ligand binding sites in mouse cerebellar neurons following in vivo ethanol administration: an autoradiographic analysis.	GABRB2 GABRB3	6.44e-05	5	89	2	7643102
Pubmed	Isoform transitions of the myosin binding protein C family in developing human and mouse muscles: lack of isoform transcomplementation in cardiac muscle.	DES MYBPC3	6.44e-05	5	89	2	9440711
Pubmed	RACK1 regulates directional cell migration by acting on G betagamma at the interface with its effectors PLC beta and PI3K gamma.	SRC PRKCB	6.44e-05	5	89	2	18596232
Pubmed	Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligase.	CUL3 KLHL1	6.44e-05	5	89	2	22632832
Pubmed	Fine mapping of Ath6, a quantitative trait locus for atherosclerosis in mice.	CYRIA APOB	6.44e-05	5	89	2	11420610
Pubmed	γ-Aminobutyric Acid Type A (GABAA) Receptor Subunits Play a Direct Structural Role in Synaptic Contact Formation via Their N-terminal Extracellular Domains.	GABRB2 GABRB3	6.44e-05	5	89	2	27129275
Pubmed	A-kinase anchoring protein 79/150 facilitates the phosphorylation of GABA(A) receptors by cAMP-dependent protein kinase via selective interaction with receptor beta subunits.	GABRB1 GABRB3	6.44e-05	5	89	2	12595241
Pubmed	Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit.	GABRB1 GABRB3	6.44e-05	5	89	2	9039914
GeneFamily	Gamma-aminobutyric acid type A receptor subunits	GABRB1 GABRB2 GABRB3	3.41e-05	19	61	3	563
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	TTC8 KIFBP CFAP70 KDM6A	6.13e-04	115	61	4	769
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRA PTPRE	2.26e-03	21	61	2	813
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	KIFAP3 SNX4 PTPRA STAG1 UBE3A XPO6 PKP4 SYNE2 DDX42 USP24 CHD9 PHF14 PPIP5K2 TTK ADGRA3	1.34e-07	856	87	15	M4500
Coexpression	GSE13229_IMM_VS_INTMATURE_NKCELL_DN	PTPRE UBE3A PRKCB EFCAB7 SLC25A28 CERS4 MGME1	4.73e-06	200	87	7	M3212
Coexpression	GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN	COQ10A CREBRF IRGM GLTP PTPRE GPR37 CNIH2 PKP4 PCNX1 PIGG EFCAB7 KDM6A CERS4 MGME1	1.53e-05	1102	87	14	M2369
Coexpression	GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN	COQ10A CREBRF IRGM GLTP PTPRE GPR37 CNIH2 PKP4 PCNX1 PIGG EFCAB7 KDM6A CERS4 MGME1	1.91e-05	1124	87	14	MM1070
Coexpression	GSE21063_3H_VS_16H_ANTI_IGM_STIM_BCELL_DN	STAG1 PKP4 CHD9 PHF14 TIMELESS PIGG	5.09e-05	197	87	6	M8271
Coexpression	GSE27786_BCELL_VS_MONO_MAC_UP	CREBRF UBE3A OTUD5 XPO6 PHF14 CHD8	5.53e-05	200	87	6	M4817
Coexpression	GSE17721_CTRL_VS_POLYIC_12H_BMDC_DN	NIBAN1 CIITA PKP4 SYNE2 PCNX1 PLA2G2F	5.53e-05	200	87	6	M3722
CoexpressionAtlas	dev gonad_e11.5_M_GonMes_Sma_k-means-cluster#1_top-relative-expression-ranked_1000	CREBRF CTNNAL1 NACC1 KCNH1 GPR37 PRKCB ADGRA3	3.34e-06	156	86	7	gudmap_dev gonad_e11.5_M_GonMes_Sma_k1_1000
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#4_top-relative-expression-ranked_1000	KIFAP3 SYNE2 SRP54 CHD8 CALCRL KDM6A	1.29e-05	127	86	6	gudmap_developingGonad_e16.5_epididymis_1000_k4
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#5_top-relative-expression-ranked_1000	UBE3A PKP4 SYNE2 CHD8 CALCRL KDM6A	3.45e-05	151	86	6	gudmap_developingGonad_P2_ovary_1000_k5
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#2_top-relative-expression-ranked_1000	GABRB1 UBE3A PKP4 SYNE2 CHD9 CHD8 CALCRL	4.15e-05	230	86	7	gudmap_developingGonad_e16.5_ovary_1000_k2
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#3_top-relative-expression-ranked_500	GABRB1 PKP4 CHD8 CALCRL KDM6A	4.66e-05	97	86	5	gudmap_developingGonad_e18.5_ovary_500_k3
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000	GABRB1 GABRB2 KIFAP3 UBE3A PKP4 SYNE2 DDX42 SRP54 CHD9 CHD8 CALCRL KDM6A	7.90e-05	790	86	12	gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000	GABRB1 CREBRF UBE3A GPR37 PKP4 SYNE2 CHD9 CHD8 CALCRL TEX11 KDM6A CERS4	8.39e-05	795	86	12	gudmap_developingGonad_e16.5_ovary_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#3_top-relative-expression-ranked_1000	UBE3A PKP4 SYNE2 DDX42 CHD9 CHD8 KDM6A	1.27e-04	275	86	7	gudmap_developingGonad_e14.5_ epididymis_1000_k3
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#2_top-relative-expression-ranked_500	PKP4 SYNE2 CHD8 KDM6A	1.41e-04	65	86	4	gudmap_developingGonad_P2_ovary_500_k2
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#2_top-relative-expression-ranked_1000	GABRB1 UBE3A PKP4 SYNE2 CHD8 CALCRL	2.12e-04	210	86	6	gudmap_developingGonad_e18.5_ovary_1000_k2
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#5_top-relative-expression-ranked_1000	SYNE2 NR5A2 CHD8 TEX11 KDM6A	2.46e-04	138	86	5	gudmap_developingGonad_e12.5_epididymis_k5_1000
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000	GABRB1 KIFAP3 UBE3A PKP4 SYNE2 NR5A2 CHD8 CALCRL TEX11 KDM6A CERS4	2.98e-04	778	86	11	gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlas	BM Top 100 - heart atrium	DES NIBAN1 RBM20 MYBPC3	2.99e-04	79	86	4	BM Top 100 - heart atrium
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#3_top-relative-expression-ranked_1000	GABRB1 UBE3A PKP4 CHD9 CHD8 KDM6A	3.07e-04	225	86	6	gudmap_developingGonad_e14.5_ ovary_1000_k3
CoexpressionAtlas	DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#2_top-relative-expression-ranked_1000	UBE3A PKP4 SYNE2 CHD9 CHD8 CALCRL KDM6A	3.39e-04	323	86	7	gudmap_developingGonad_e11.5_ovary + mesonephros_k2_1000
CoexpressionAtlas	dev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#1_top-relative-expression-ranked_1000	GPR37 SYNE2 PRKCB ADGRA3	3.45e-04	82	86	4	gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k1_1000
CoexpressionAtlas	dev gonad_e13.5_M_SertoliCell_Sox9_top-relative-expression-ranked_500	CREBRF CTNNAL1 PTPRE KCNH1 GPR37 SYNE2 ADGRA3 MYBPC3	3.71e-04	433	86	8	gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_500
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_1000	GABRB1 KIFAP3 UBE3A GPR37 PKP4 SYNE2 CHD9 CHD8 CALCRL PPIP5K2 KDM6A	3.94e-04	804	86	11	gudmap_developingGonad_e12.5_ovary_1000
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_1000	KIFAP3 PTPRE KCNH1 GPR37 PKP4 SYNE2 NR5A2 CHD9 CHD8 TEX11 KDM6A	4.02e-04	806	86	11	gudmap_developingGonad_e12.5_epididymis_1000
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRB2 GABRB3 KIFAP3 UBE3A KCNH1 CHD5 PRKCB CNKSR2	5.36e-09	196	88	8	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	GABRB2 GABRB3 KIFAP3 UBE3A KCNH1 CHD5 PRKCB CNKSR2	6.28e-09	200	88	8	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF13B DES NIBAN1 NOP58 STAG1 SRP54 CHD9	1.22e-07	195	88	7	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRB2 GABRB3 KIFAP3 UBE3A CHD5 PRKCB CNKSR2	1.35e-07	198	88	7	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRB2 GABRB3 KIFAP3 UBE3A CHD5 PRKCB CNKSR2	1.35e-07	198	88	7	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRB2 GABRB3 KIFAP3 UBE3A CHD5 PRKCB CNKSR2	1.35e-07	198	88	7	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	LPS_only-Endothelial\|LPS_only / Treatment groups by lineage, cell group, cell type	CTNNAL1 PKP4 SYNE2 NR5A2 GBP3 CALCRL N4BP3	1.45e-07	200	88	7	81e76508c9050d533853d5fd2f3097b27613d836
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	CTNNAL1 PKP4 SYNE2 NR5A2 GBP3 CALCRL N4BP3	1.45e-07	200	88	7	3585484c7e24e941708bee471ca607d8ccee74e6
ToppCell	LPS_only-Endothelial-Endothelial\|LPS_only / Treatment groups by lineage, cell group, cell type	CTNNAL1 PKP4 SYNE2 NR5A2 GBP3 CALCRL N4BP3	1.45e-07	200	88	7	4bb609a284d4e6066f17470a1736076aa4a1f84c
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF13B STAG1 SRP54 CHD9 KDM6A RBM20	1.37e-06	176	88	6	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF13B IRGM STAG1 SYNE2 SRP54 GBP3	1.46e-06	178	88	6	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	COVID-19-Heart-CM_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GABRB1 DOCK3 DES NIBAN1 RBM20 MYBPC3	1.77e-06	184	88	6	e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	RALGAPA1 ARID1B SYNE2 USP24 PCNX1 KDM6A	2.00e-06	188	88	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	ILEUM-non-inflamed-(1)_T_cell-(1)_CD8_Trm\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CUL3 KIF13B NIBAN1 SYNE2 PCNX1 CHD6	2.07e-06	189	88	6	2c8a2fb76ea002bac554bc1c761ce960b5e116e1
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CTNNAL1 CIITA PKP4 NR5A2 GBP3 CALCRL	2.20e-06	191	88	6	a7b18bcf27c38ad2353c239ecb309c80f3ef3359
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRB2 GABRB3 KIFAP3 UBE3A CHD5 CNKSR2	2.70e-06	198	88	6	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Vein\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	RALGAPA1 CTNNAL1 KLHL1 PKP4 SYNE2 CALCRL	2.86e-06	200	88	6	7eb366b2c5394af7c77650bde6261e7dac67154e
ToppCell	LPS_only-Endothelial-Endothelial-Vein\|LPS_only / Treatment groups by lineage, cell group, cell type	CTNNAL1 KLHL1 PKP4 SYNE2 GBP3 CALCRL	2.86e-06	200	88	6	b036f5e22c95a3b14391785b6e91aa183b9bc9a8
ToppCell	Endothelial-F\|World / shred on cell class and cell subclass (v4)	IRGM CIITA GBP3 CALCRL N4BP3	8.35e-06	139	88	5	32d3c5d35e6c4205711c3500d736fd108443e6b4
ToppCell	367C-Lymphocytic-ILC-ILC-3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PABPC3 CNIH2 PPIP5K1 DESI2 MGME1	1.70e-05	161	88	5	8de421c61f4d5a6e05fdb20e4d230e2db98ee4d5
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	RALGAPA1 SYNE2 PCNX1 USP9Y KDM6A	1.75e-05	162	88	5	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYRIA PTPRE SYNE2 PRKCB PCNX1	2.54e-05	175	88	5	cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK3 DES NIBAN1 RBM20 MYBPC3	2.61e-05	176	88	5	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	E17.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GABRB2 CTNNAL1 KLHL1 KCNH1 CALCRL	2.75e-05	178	88	5	0139b42494c1186390b12106dea7957e2b6717c2
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CUL3 NIBAN1 CTNNAL1 SYNE2 PCNX1	2.90e-05	180	88	5	6bb9f41c3a99d1bbe697f589fb2bcea9b7bfbeee
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK3 DES NIBAN1 RBM20 MYBPC3	2.98e-05	181	88	5	719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell	LPS-IL1RA\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIFBP CTNNAL1 GLTP GBP3 CALCRL	3.22e-05	184	88	5	c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK3 DES NIBAN1 RBM20 MYBPC3	3.31e-05	185	88	5	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	PCW_05-06-Endothelial-Endothelial_mature-lymphatic\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	NIBAN1 PTPRE NR5A2 CALCRL N4BP3	3.40e-05	186	88	5	86b218a400f9c64f92b050f00b49f09647b17437
ToppCell	PCW_05-06-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	NIBAN1 PTPRE NR5A2 CALCRL N4BP3	3.40e-05	186	88	5	f51c76b1c3c6c49e0ebc9a913d8413e0b6a04d80
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CTNNAL1 PKP4 NR5A2 CHD8 CALCRL	3.57e-05	188	88	5	524d1d928c9386acf20e53d31894107dd7290dc7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GABRB1 DOCK3 PKP4 CFAP70 RBM20	3.57e-05	188	88	5	2ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRB3 KCNH1 PRKCB CNKSR2 KCNH5	3.57e-05	188	88	5	50c1b1d690f0e9443082f2adf4f1b8e9ce4cd337
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CTNNAL1 PKP4 NR5A2 CHD8 CALCRL	3.57e-05	188	88	5	1b57995d70cf81212e8d46dfaf44dbaf9c7bc4d5
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CTNNAL1 PKP4 NR5A2 CHD8 CALCRL	3.57e-05	188	88	5	cd2d1f8e43c252dd8730a5758458ef63e7ffc836
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CTNNAL1 PKP4 NR5A2 CHD8 CALCRL	3.57e-05	188	88	5	f5a2f324f3f6c5078d57130392d3f1ba74f29094
ToppCell	5'-Airway_Nasal-Endothelial\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CTNNAL1 PKP4 NR5A2 CHD8 CALCRL	3.57e-05	188	88	5	6c9d5e4014f807149328ff4eabd5e86dfe18094d
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRB3 CTNNAL1 KCNH1 PRKCB CNKSR2	3.76e-05	190	88	5	d594da827e3c16644952b9589cc12b947ce36279
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	NOP58 STAG1 MCMDC2 CHD6 MYBPC3	3.85e-05	191	88	5	6e1d00404d795ec7cf60f685e42e4ad9a16ac596
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	NOP58 STAG1 MCMDC2 CHD6 MYBPC3	3.85e-05	191	88	5	f158e393976b685b896a41871bda1ab65a8b58f5
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF13B DES NOP58 STAG1 CHD9	3.85e-05	191	88	5	7d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCell	COPD-Lymphoid\|COPD / Disease state, Lineage and Cell class	RALGAPA1 NIBAN1 NOP58 SYNE2 PRKCB	3.95e-05	192	88	5	064fefb8212fadab0ff441f4bf643559b7fdb25d
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Vein\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CTNNAL1 KLHL1 PKP4 NR5A2 CALCRL	3.95e-05	192	88	5	81baf1c4063469bb0c03a8602b40e387ba7b0dfb
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CYRIA NIBAN1 PTPRE CIITA PRKCB	4.05e-05	193	88	5	3e3d7cb3e7242ec9c9677e07e303835649852b52
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CYRIA ARID1B STAG1 PCNX1 KDM6A	4.05e-05	193	88	5	779276e775cb2492e8dd36436295a536084a6415
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CYRIA NIBAN1 PTPRE CIITA PRKCB	4.15e-05	194	88	5	badefcec2af86cbcd97305f4843e84db0f3ebc66
ToppCell	COVID-19-Heart-CM_1\|Heart / Disease (COVID-19 only), tissue and cell type	GABRB1 DOCK3 NIBAN1 RBM20 MYBPC3	4.25e-05	195	88	5	f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CTNNAL1 CIITA PKP4 NR5A2 CALCRL	4.25e-05	195	88	5	56efeb58df19f357d7d5ce87348d4f196a595421
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	DOCK3 DES NIBAN1 RBM20 MYBPC3	4.25e-05	195	88	5	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CYRIA NIBAN1 PTPRE CIITA PRKCB	4.36e-05	196	88	5	291c59b609985167c98a40d4e2caeea2fad74941
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CYRIA NIBAN1 PTPRE CIITA PRKCB	4.46e-05	197	88	5	0523aec9713ae21e6b879aa98e07fa2576610d5f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CYRIA NIBAN1 PTPRE CIITA PRKCB	4.46e-05	197	88	5	57dafb3047745a44b2345b8036e159c3641d496e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CYRIA NIBAN1 PTPRE CIITA PRKCB	4.46e-05	197	88	5	826cc6baafab13e7ef5cfcf28cd79d0fbf3af38d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CYRIA NIBAN1 PTPRE CIITA PRKCB	4.57e-05	198	88	5	96883ad8e189a46ed5b7eaafc0543e53682d26ed
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRB2 GABRB3 KIFAP3 UBE3A CHD5	4.57e-05	198	88	5	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CYRIA NIBAN1 PTPRE CIITA PRKCB	4.57e-05	198	88	5	623f9d64c9e800d2d7f623392bf2f22b563f0249
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CYRIA NIBAN1 PTPRE CIITA PRKCB	4.68e-05	199	88	5	04adf46975aa4194ea40c7480f8a517def5d929c
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RALGAPA1 ARID1B SYNE2 USP24 USP9Y	4.68e-05	199	88	5	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Vein\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	RALGAPA1 CTNNAL1 KLHL1 PKP4 CALCRL	4.68e-05	199	88	5	cfb624c7728046fc7f3ef071f57e4d7b013f3fef
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CTNNAL1 PKP4 SYNE2 CALCRL N4BP3	4.79e-05	200	88	5	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CTNNAL1 PKP4 SYNE2 NR5A2 CALCRL	4.79e-05	200	88	5	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	CTNNAL1 PKP4 NR5A2 GBP3 CALCRL	4.79e-05	200	88	5	6f531a418ff25b59a543800cf4bce7b72404ce08
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CTNNAL1 PKP4 SYNE2 CALCRL N4BP3	4.79e-05	200	88	5	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CTNNAL1 SYNE2 GBP3 CALCRL N4BP3	4.79e-05	200	88	5	79e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW09-Stem_cells-Stem_cells\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	CTNNAL1 SYNE2 TIMELESS PTBP1 MGME1	4.79e-05	200	88	5	c00cc0b91baa37828895d9d6b8acbc6aa503215a
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW09-Stem_cells\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	CTNNAL1 SYNE2 TIMELESS PTBP1 MGME1	4.79e-05	200	88	5	9e1b62a703fb7d413ce580448a1df5127c28e8a7
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CTNNAL1 PKP4 NR5A2 CALCRL N4BP3	4.79e-05	200	88	5	f15fffefe372005c33e31845982e2d2714ac26af
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CTNNAL1 PKP4 SYNE2 NR5A2 CALCRL	4.79e-05	200	88	5	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	CTNNAL1 PKP4 NR5A2 CALCRL N4BP3	4.79e-05	200	88	5	b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCell	LV-03._Atrial_Cardiomyocyte\|LV / Chamber and Cluster_Paper	GPR37 APOB RBM20 MYBPC3	9.44e-05	120	88	4	3b77bd0e3630cdd45001cecf5e47660a90ebc92e
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	SYNE2 APOB SPATA22 USP9Y	9.75e-05	121	88	4	19333a660800b583fa27b495c1f7828e6636a257
ToppCell	Control-PLT_5\|World / Disease Group and Platelet Clusters	GABRB2 CFAP70 ADGRA3 KCNH5	1.14e-04	126	88	4	4ba753c4e83eb1d41964edfa22135e047f06c481
ToppCell	TCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3\|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9	TTC8 CHD9 PPIP5K2 KDM6A	1.49e-04	135	88	4	ac20133d4a36f48338b45bffb13e842cb66f83ad
ToppCell	PBMC-Control-Hematopoietic-Platelet-Platelet-plt_5\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GABRB2 CFAP70 ADGRA3 KCNH5	1.53e-04	136	88	4	27a41463e6f16deb5b1d4f17fefded9959038c07
ToppCell	PBMC-Control-Hematopoietic-Platelet-Platelet-plt_5\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GABRB2 CFAP70 ADGRA3 KCNH5	1.53e-04	136	88	4	88b5c839d0446c6d6b7e81fc4d48f5e7e96eea11
ToppCell	TCGA-Bile_Duct\|World / Sample_Type by Project: Shred V9	CYP3A5 NR5A2 APOB KLKB1	1.71e-04	140	88	4	ca8a0ccbc2f501b759864fe9bb06dc8b44b6b31f
ToppCell	LPS-antiTNF-Unknown-Endothelial-Monocytes-Macrophages\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NR5A2 PRKCB GBP3 CHD8	1.81e-04	142	88	4	b66f9602dba30d1d4fbcc49ceb112eb5bd916ba1
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	RALGAPA1 ARID1B PCNX1 USP9Y	2.06e-04	147	88	4	94998bc40f5c08295cfe3bdcbe43f13b1e564b3d
ToppCell	367C-Lymphocytic-ILC-ILC-3\|367C / Donor, Lineage, Cell class and subclass (all cells)	PABPC3 CNIH2 PPIP5K1 MGME1	2.40e-04	153	88	4	9d64aadbb4bb28469af1d728457b431e21577429
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	RALGAPA1 SYNE2 PCNX1 KDM6A	2.59e-04	156	88	4	1545169694f686d28648a68b552c2ae606599d66
ToppCell	facs-Heart-Unknown-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR37 APOB KLKB1 MYBPC3	2.65e-04	157	88	4	8d30d8e6fae93afcada6bd68799439335cd65b69
ToppCell	facs-Heart-Unknown-3m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR37 APOB KLKB1 MYBPC3	2.65e-04	157	88	4	2ac4695d9e4ca8d4ba19c555e9a1d86ac8f398ab
ToppCell	facs-Heart-Unknown-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR37 APOB KLKB1 MYBPC3	2.65e-04	157	88	4	8a393eece90fb9a1b7c356736bdb36277261fbd3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NIBAN1 PTPRE NR5A2 CALCRL	2.92e-04	161	88	4	fb59d96c2aa9e4654f02bf6ce36bf832776cb4dd
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NIBAN1 PTPRE NR5A2 CALCRL	2.92e-04	161	88	4	c53c461fc721a7960cef86662f49e2a495520701
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	KCNH1 PRKCB CNKSR2 KCNH5	2.92e-04	161	88	4	ebcd5066e82b7760b9da6adc02d11258d1309dab
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DOCK3 PLA2G2F USP9Y KLKB1	2.98e-04	162	88	4	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NIBAN1 PTPRE NR5A2 CALCRL	2.98e-04	162	88	4	2ac02523348660e514d464f8f2434ee0c312d784
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYRIA PTPRE CIITA CAGE1	2.98e-04	162	88	4	93bd29c52846c3156b8b0d2e39c552373efdfe93
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CTNNAL1 PKP4 NR5A2 CALCRL	3.27e-04	166	88	4	f7926ee266dcbf10df375cd921f1db5a2fa604f8
ToppCell	BAL-Severe-cDC_5\|Severe / Compartment, Disease Groups and Clusters	CNIH2 CALCRL N4BP3 ADCY3	3.43e-04	168	88	4	857a80c217a5513553460798a625612031bc7bb7
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	COQ10A TTC8 CNIH2 PIGG	3.43e-04	168	88	4	ca94b29c1030484143a77f2df06dad74d2c6136e
ToppCell	PND10-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TTC8 PTPRE GBP3 PPIP5K1	3.43e-04	168	88	4	c3d2d573f21350a4a674faff30b06ff644d00ac3
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-TRGV2_gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DOCK3 IRGM PCNX1 ZC3H12B	3.50e-04	169	88	4	8caf7996796a2e2716e3855de855c903d6126bf2
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK3 DES RBM20 MYBPC3	3.58e-04	170	88	4	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	DOCK3 PRKCB RBM20 MYBPC3	3.58e-04	170	88	4	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GABRB2 DES CNKSR2 RBM20	3.58e-04	170	88	4	cb1ed6bd409ee1cf11be0d5e7cdcffe2ab220d38
ToppCell	3'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYRIA PTPRE PRKCB MYBPC3	3.58e-04	170	88	4	46a81d505de845cc59f80594fce338f7fdb9250f
ToppCell	3'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYRIA PTPRE PRKCB MYBPC3	3.58e-04	170	88	4	1a9a0487c35cf3fd5806d1f0f0e91ef0e0b9cd0a
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GABRB2 DES CNKSR2 RBM20	3.58e-04	170	88	4	da4fb1e186e9bec6bba0b25f2a0e68f9e11c6017
Computational	Neurotransmitter (GABA) receptor.	GABRB1 GABRB2 GABRB3	4.66e-05	15	52	3	MODULE_215
Drug	Adinazolam	GABRB1 GABRB2 GABRB3	3.19e-06	8	89	3	DB00546
Drug	Fludiazepam	GABRB1 GABRB2 GABRB3	3.19e-06	8	89	3	DB01567
Drug	Clotiazepam	GABRB1 GABRB2 GABRB3	3.19e-06	8	89	3	DB01559
Drug	Cinolazepam	GABRB1 GABRB2 GABRB3	3.19e-06	8	89	3	DB01594
Drug	Prazepam	GABRB1 GABRB2 GABRB3	3.19e-06	8	89	3	DB01588
Drug	Estazolam	GABRB1 GABRB2 GABRB3	3.19e-06	8	89	3	DB01215
Drug	Halazepam	GABRB1 GABRB2 GABRB3	3.19e-06	8	89	3	DB00801
Drug	1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane	GABRB1 GABRB2 GABRB3	3.19e-06	8	89	3	ctd:C091518
Drug	Ethchlorvynol	GABRB1 GABRB2 GABRB3	4.77e-06	9	89	3	DB00189
Drug	Diazepam	GABRB1 GABRB2 GABRB3	4.77e-06	9	89	3	DB00829
Drug	3-isothujone	GABRB1 GABRB2 GABRB3 CYP3A5	5.53e-06	30	89	4	CID000011027
Drug	Chlordiazepoxide	GABRB1 GABRB2 GABRB3	6.79e-06	10	89	3	DB00475
Drug	Clobazam	GABRB1 GABRB2 GABRB3	6.79e-06	10	89	3	DB00349
Drug	Bromazepam	GABRB1 GABRB2 GABRB3	6.79e-06	10	89	3	DB01558
Drug	Oxazepam	GABRB1 GABRB2 GABRB3	6.79e-06	10	89	3	DB00842
Drug	Midazolam	GABRB1 GABRB2 GABRB3	6.79e-06	10	89	3	DB00683
Drug	Flurazepam	GABRB1 GABRB2 GABRB3	6.79e-06	10	89	3	DB00690
Drug	Clonazepam	GABRB1 GABRB2 GABRB3	6.79e-06	10	89	3	DB01068
Drug	acetophenone	CYP3A5 KCNH1 KDM6A ADCY3	7.21e-06	32	89	4	CID000007410
Drug	Alprazolam	GABRB1 GABRB2 GABRB3	9.31e-06	11	89	3	DB00404
Drug	Temazepam	GABRB1 GABRB2 GABRB3	9.31e-06	11	89	3	DB00231
Drug	Nitrazepam	GABRB1 GABRB2 GABRB3	9.31e-06	11	89	3	DB01595
Drug	Lorazepam	GABRB1 GABRB2 GABRB3	9.31e-06	11	89	3	DB00186
Drug	Triazolam	GABRB1 GABRB2 GABRB3	9.31e-06	11	89	3	DB00897
Drug	Clorazepate	GABRB1 GABRB2 GABRB3	9.31e-06	11	89	3	DB00628
Drug	Etomidate	GABRB1 GABRB2 GABRB3	9.31e-06	11	89	3	ctd:D005045
Drug	secobarbital	GABRB1 GABRB2 GABRB3 CYP3A5	1.31e-05	37	89	4	CID000005193
Drug	I5B1	DES CYP3A5 NR5A2 PRKCB	1.31e-05	37	89	4	CID005487705
Drug	phaclofen	GABRB1 GABRB2	1.51e-05	2	89	2	ctd:C052329
Drug	pentobarbital	GABRB1 GABRB2 GABRB3 CYP3A5 KCNH1 PRKCB KCNH5	2.82e-05	224	89	7	CID000004737
Drug	lindane	GABRB1 GABRB2 GABRB3 CYP3A5 ARHGEF16 CERS4	3.18e-05	154	89	6	CID000000727
Drug	zolpidem	GABRB1 GABRB2 GABRB3	3.77e-05	17	89	3	ctd:C049109
Drug	dihydroxyaflavinine	GABRB1 GABRB2 GABRB3	3.77e-05	17	89	3	CID000156857
Drug	Muscimol	GABRB1 GABRB2 GABRB3	5.35e-05	19	89	3	ctd:D009118
Drug	triazolam	GABRB1 GABRB2 GABRB3 CYP3A5	5.94e-05	54	89	4	CID000005556
Drug	endrine	GABRB1 GABRB2 GABRB3 CYP3A5 ADCY3	6.05e-05	106	89	5	CID000003048
Drug	delta-hexachlorocyclohexane	GABRB1 GABRB2 GABRB3	6.27e-05	20	89	3	ctd:C086916
Drug	cisapride	CYP3A5 KCNH1 PTBP1 ADCY3 KCNH5	7.87e-05	112	89	5	CID000002769
Drug	flunitrazepam	GABRB1 GABRB2 GABRB3 CYP3A5	8.42e-05	59	89	4	CID000003380
Drug	AC1Q3G0K	DOCK3 KIFBP CYP3A5 ADCY3	9.00e-05	60	89	4	CID000002087
Drug	2,6-diisopropyl-4-(3-(3-methyl-3H-diazirin-3-yl)propyl)phenol	GABRB2 GABRB3	9.02e-05	4	89	2	ctd:C570407
Drug	Propofol	GABRB2 GABRB3	9.02e-05	4	89	2	DB00818
Drug	loreclezole	GABRB2 GABRB3	9.02e-05	4	89	2	ctd:C066440
Drug	Fospropofol	GABRB2 GABRB3	9.02e-05	4	89	2	DB06716
Drug	pf26	KIFBP CYP3A5	9.02e-05	4	89	2	CID000032197
Drug	pentanol	CYP3A5 KCNH1 ADCY3	9.66e-05	23	89	3	CID000006276
Drug	diazepam	GABRB1 GABRB2 GABRB3 TTC8 CYP3A5 ADCY3	9.92e-05	189	89	6	CID000003016
Drug	methohexital	GABRB1 GABRB2 GABRB3	1.10e-04	24	89	3	CID000009034
Drug	Mefloquine hydrochloride [51773-92-3]; Down 200; 9.6uM; MCF7; HT_HG-U133A	PTPRA UBE3A PKP4 USP24 PPIP5K2 SLC25A28	1.11e-04	193	89	6	6205_DN
Drug	Austricine [10180-88-8]; Down 200; 14.2uM; MCF7; HT_HG-U133A	PTPRE UBE3A PKP4 PPIP5K2 KDM6A ADCY3	1.24e-04	197	89	6	2812_DN
Drug	Heliotrine [303-33-3]; Up 200; 12.8uM; MCF7; HT_HG-U133A	NIBAN1 KLHL1 CYP3A5 UBE3A PCNX1 APOB	1.32e-04	199	89	6	3615_UP
Drug	enflurane	GABRB1 GABRB2 GABRB3 CYP3A5	1.47e-04	68	89	4	CID000003226
Drug	hexane	RALGAPA1 GLTP CYP3A5 KCNH1	1.47e-04	68	89	4	CID000008058
Drug	alphaxalone	GABRB2 GABRB3	1.50e-04	5	89	2	ctd:C006477
Drug	Advicor	SYNE2 APOB	1.50e-04	5	89	2	CID000151176
Drug	tert-butylbicyclophosphorothionate	GABRB2 GABRB3	1.50e-04	5	89	2	ctd:C037476
Disease	autism spectrum disorder (implicated_via_orthology)	GABRB3 ARID1B UBE3A PKP4 CHD9 CHD8 CHD6	3.47e-07	152	87	7	DOID:0060041 (implicated_via_orthology)
Disease	CHARGE syndrome (implicated_via_orthology)	CHD9 CHD8 CHD6	8.59e-07	7	87	3	DOID:0050834 (implicated_via_orthology)
Disease	Epilepsy	GABRB2 GABRB3 ARID1B UBE3A KCNH1 KCNH5	8.76e-07	109	87	6	C0014544
Disease	Epilepsy, Cryptogenic	GABRB2 GABRB3 ARID1B UBE3A KCNH1	4.53e-06	82	87	5	C0086237
Disease	Awakening Epilepsy	GABRB2 GABRB3 ARID1B UBE3A KCNH1	4.53e-06	82	87	5	C0751111
Disease	Aura	GABRB2 GABRB3 ARID1B UBE3A KCNH1	4.53e-06	82	87	5	C0236018
Disease	Neurodevelopmental Disorders	GABRB2 GABRB3 CUL3 ARID1B KCNH1	8.41e-06	93	87	5	C1535926
Disease	N-stearoyl-sphingosine (d18:1/18:0) measurement	SYNE2 CERS4	2.57e-05	3	87	2	EFO_0800613
Disease	proprotein convertase subtilisin/kexin type 9 measurement	USP24 APOB CNKSR2	3.66e-05	22	87	3	EFO_0009312
Disease	Angelman Syndrome	GABRB3 UBE3A	5.14e-05	4	87	2	C0162635
Disease	congenital heart disease (implicated_via_orthology)	CHD9 CHD8 CHD6 MYBPC3	5.27e-05	69	87	4	DOID:1682 (implicated_via_orthology)
Disease	Sphingomyelin (d18:1/20:0, d16:1/22:0) measurement	SYNE2 CERS4	8.54e-05	5	87	2	EFO_0022109
Disease	hearing threshold measurement, pure tone hearing measurement	GLTP ADGRA3	8.54e-05	5	87	2	EFO_0007617, EFO_0007618
Disease	level of Sphingomyelin (d38:1) in blood serum	SYNE2 USP24 CERS4	9.49e-05	30	87	3	OBA_2045180
Disease	vasoactive peptide measurement	KCNH1 KLKB1	1.28e-04	6	87	2	EFO_0005196
Disease	stearoyl sphingomyelin (d18:1/18:0) measurement	SYNE2 CERS4	1.28e-04	6	87	2	EFO_0800611
Disease	Primary dilated cardiomyopathy	DES RBM20 MYBPC3	1.39e-04	34	87	3	cv:C0007193
Disease	glycosyl ceramide (d18:1/20:0, d16:1/22:0) measurement	SYNE2 CERS4	1.79e-04	7	87	2	EFO_0800551
Disease	QRS-T angle	DES PCNX1 RBM20 MYBPC3	2.78e-04	106	87	4	EFO_0020097
Disease	dilated cardiomyopathy (is_implicated_in)	DES PRKCB RBM20	2.81e-04	43	87	3	DOID:12930 (is_implicated_in)
Disease	Familial dilated cardiomyopathy	DES RBM20 MYBPC3	3.00e-04	44	87	3	C0340427
Disease	level of Sphingomyelin (d36:1) in blood serum	CERS4 KCNH5	3.05e-04	9	87	2	OBA_2045178
Disease	Neuroblastoma	ARID1B CHD5 CHD6	3.65e-04	47	87	3	C0027819
Disease	Cardiomyopathy	DES RBM20 MYBPC3	3.65e-04	47	87	3	cv:C0878544
Disease	developmental disorder of mental health (implicated_via_orthology)	GABRB1 GABRB2 GABRB3	4.14e-04	49	87	3	DOID:0060037 (implicated_via_orthology)
Disease	Cardiomyopathies	DES RBM20 NDUFS2 MYBPC3	6.03e-04	130	87	4	C0878544
Disease	ceramide measurement	GABRB1 SYNE2 APOB CERS4 ADGRA3	6.67e-04	235	87	5	EFO_0010222
Disease	urate measurement, spine bone mineral density	KCNH1 SRC RBM20	6.79e-04	58	87	3	EFO_0004531, EFO_0007701
Disease	Autistic Disorder	GABRB1 GABRB3 UBE3A PRKCB CHD8	1.07e-03	261	87	5	C0004352
Disease	level of Sphingomyelin (d32:1) in blood serum	SYNE2 KCNH5	1.14e-03	17	87	2	OBA_2045173
Disease	Cardiomegaly	SRC PRKCB MYBPC3	1.85e-03	82	87	3	C0018800
Disease	Cardiac Hypertrophy	SRC PRKCB MYBPC3	1.85e-03	82	87	3	C1383860
Disease	hypertrophic cardiomyopathy (is_implicated_in)	NDUFS2 MYBPC3	1.91e-03	22	87	2	DOID:11984 (is_implicated_in)
Disease	Dyslipidemias	NR5A2 APOB	2.27e-03	24	87	2	C0242339
Disease	Dyslipoproteinemias	NR5A2 APOB	2.27e-03	24	87	2	C0598784
Disease	colon adenocarcinoma (is_implicated_in)	SRC KDM6A	2.67e-03	26	87	2	DOID:234 (is_implicated_in)
Disease	level of Sterol ester (27:1/16:0) in blood serum	USP24 APOB	2.67e-03	26	87	2	OBA_2045191
Disease	alcohol use disorder (implicated_via_orthology)	ARID1B PRKCB KDM6A NDUFS2	2.68e-03	195	87	4	DOID:1574 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
MEQFGQQQYDIYERM	PKP4	361	Q99569
MNAEVYYMHEDILQN	ERVPABLB-1	366	P60509
GSLASRQMIQQYEMY	CHD8	891	Q9HCK8
MVNYMQYQQVCDALF	CERS4	251	Q9HA82
NYVCLQERYMTEMQQ	CAGE1	416	Q8TC20
TVMYRNYQRKNDMDE	CHD5	536	Q8TDI0
MEQAQAYVMRYFESS	CIITA	571	P33076
TYDAVVQMEYLDMVV	CYP3A5	346	P20815
FMYELDREMNYQQNP	CREBRF	41	Q8IUR6
YANDVTRVLYMFNQM	ADGRA3	416	Q8IWK6
KSEESYMVQDYAQMN	ARHGEF16	541	Q5VV41
YMVQDYAQMNHIQVE	ARHGEF16	546	Q5VV41
RHEGDMYNMQYSSQQ	ARID1B	1456	Q8NFD5
MGANQLVVLNVYDMY	DESI2	1	Q9BSY9
IKMQVYFDMNYTNRV	CFAP206	81	Q8IYR0
AAQAMVQYYQEKSAV	RBM20	566	Q5T481
EYRTQLYEYLQNRMM	NOP58	266	Q9Y2X3
NEVNNEMANRMSLFY	CYRIA	176	Q9H0Q0
QMVQTDMQYTFIYQA	PTPRE	376	P23469
QNSQYQDMVASVMYT	OR1B1	271	Q8NGR6
DYTSQRFYMMQGIVI	MCMDC2	121	Q4G0Z9
QVVAYMGAMNHDTNY	MGME1	271	Q9BQP7
LENYLMEMQFNRYDF	IRGM	101	A1A4Y4
EQYKMEDLMQVYDQF	KDM6A	1376	O15550
FQQMYANTNRYHEML	KCNH5	471	Q8NCM2
MDRGNNNVMSNYEAY	DDX42	671	Q86XP3
LEYNQYEVRNAATMM	PCNX1	1331	Q96RV3
AEVVKQRMQMYNSPY	SLC25A28	191	Q96A46
IFQQMYANTNRYHEM	KCNH1	501	O95259
MGTINQQAMDQLYYV	GBP3	131	Q9H0R5
SEVNMDYTLTMYFQQ	GABRB1	76	P18505
EVNMDYTLTMYFQQA	GABRB2	76	P47870
SEVNMDYTLTMYFQQ	GABRB3	76	P28472
QTMDRLYFVMEYVNG	PRKCB	411	P05771
NMVLCLMNQTYREEY	PLA2G2F	116	Q9BZM2
NYYFERNMRMIQIQE	PHF14	621	O94880
YVSMMCNEQAYSLAV	NDUFS2	141	O75306
AYLTNEYMQRMASVR	PABPC3	376	Q9H361
MRRMICLNDEAYNNY	PPP4R3C	561	Q6ZMV5
DRMYQMDIQQELQRY	APOB	2521	P04114
SLISRQMIQQYEMYF	CHD9	941	Q3L8U1
QMIQQYEMYFRDSQG	CHD9	946	Q3L8U1
RAATNVQMYYEMIEN	GPR37	361	O15354
MEASYYDNIMEQQRL	DOCK3	1336	Q8IZD9
NEIVQYGRNMSSMAY	CTNNAL1	591	Q9UBT7
QYRMQIAQRSMVYLT	EFCAB7	291	A8K855
RQMIQQYEMVYRDAQ	CHD6	546	Q8TD26
YYEIQNNDIRMEMAF	CFAP70	746	Q5T0N1
DILMYMDRVYVQQNN	CUL3	121	Q13618
SMQEMYEVVSNVQEY	COQ10A	96	Q96MF6
MMEYRHQIQSYTCEI	DES	321	P17661
QFNTMYMYRHENVSI	ADCY3	306	O60266
AQVLVYDDETYMMQD	ELF2	51	Q15723
IDVIYEMYTQMNAEL	GLTP	191	Q9NZD2
VASMYTPNAQYCQMR	KLKB1	36	P03952
IMTAQYECYQKIMQD	CALCRL	41	Q16602
RQIQFEIAHAYYDMM	KIFBP	471	Q96EK5
MVESRQMDESEQYLY	KIFAP3	686	Q92845
QAMAEMYNRPVEVYQ	OTUD5	286	Q96G74
RCQMVQTDMQYVFIY	PTPRA	481	P18433
MQVSQFKMVNYSYDE	NR5A2	66	O00482
NFNYEYAQMEVTMKA	KIF13B	586	Q9NQT8
RNAMNMQETYTAYLI	SNX4	71	O95219
AQIASGMAYVERMNY	SRC	371	P12931
QFTLRDMYEQFQNIM	SRP54	326	P61011
VKIADVEMQYYINVM	SPATA22	346	Q8NHS9
IYDQLYDEVNMMTIR	SYNE2	5281	Q8WXH0
MYDAVSIMNADILNY	CNIH2	116	Q6PI25
YMSNEKIAQEEYMFQ	CNKSR2	471	Q8WXI2
IEQNLTNYYEMMLTD	TIMELESS	411	Q9UNS1
RIYEEMNNMSSAAEY	TTC8	326	Q8TAM2
LYRNVMMETYGNVVS	ZNF250	46	P15622
YNADQIRRMMETFQQ	UBE3A	331	Q05086
ILNIYRYMVVQVSMD	RALGAPA1	561	Q6GYQ0
NYMQELMENAVFTFE	NIBAN1	441	Q9BZQ8
VQKTLYQEVMMENYD	ZNF607	26	Q96SK3
YQEVMMENYDNLVSL	ZNF607	31	Q96SK3
SYETQMNMLYSQLVE	TEX11	906	Q8IYF3
IRQCQYSIIYDEYMM	STAG1	186	Q8WVM7
ATCYMNSVIQQLYMI	USP9Y	1566	O00507
NINSMHNREYYMAEV	ZC3H12B	556	Q5HYM0
ATCYMNAVFQQLYMQ	USP24	1696	Q9UPU5
QYIYMVMECGNIDLN	TTK	596	P33981
NELNYMTQIVIMLYE	PPIP5K2	861	O43314
RNDYVMMYSLTVFEN	XPO6	56	Q96QU8
QVAQYDIYSMMVGTV	PIGG	426	Q5H8A4
MNTEEAANTMVNYYT	PTBP1	101	P26599
YMTQIVIMLYEDNTQ	PPIP5K1	881	Q6PFW1
YTMENIMEVIRNQEF	KLHL1	336	Q9NR64
EGMDEQYRQICNMYT	NACC1	291	Q96RE7
YMDMYRRNQALEQEL	N4BP3	511	O15049
VYEMRVYAVNAIGMS	MYBPC3	841	Q14896