Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent

MEGF9 MUC2 MUC3A

7.12e-04188193GO:0005201
GeneOntologyMolecularFunctionstructural molecule activity

MEGF9 MUC2 MUC3A POM121L2

8.92e-03891194GO:0005198
GeneOntologyCellularComponentGolgi lumen

MUC2 MUC16 MUC3A MUC5B MUC3B MUC12

6.39e-10109206GO:0005796
DomainSEA_dom

MUC16 MUC3A MUC3B MUC12

6.69e-0923194IPR000082
DomainSEA

MUC16 MUC3A MUC3B MUC12

6.69e-0923194PS50024
DomainSEA

MUC16 MUC3A MUC3B

3.23e-0714193SM00200
DomainSEA

MUC16 MUC3B MUC12

1.36e-0622193PF01390
DomainWxxW_domain

MUC2 MUC5B

1.47e-056192IPR025155
DomainMucin2_WxxW

MUC2 MUC5B

1.47e-056192PF13330
DomainTIL

MUC2 MUC5B

6.43e-0512192PF01826
DomainC8

MUC2 MUC5B

6.43e-0512192PF08742
DomainC8

MUC2 MUC5B

7.60e-0513192SM00832
DomainUnchr_dom_Cys-rich

MUC2 MUC5B

7.60e-0513192IPR014853
DomainTIL_dom

MUC2 MUC5B

8.86e-0514192IPR002919
DomainEGF_1

MEGF9 MUC3A MUC3B MUC12

1.12e-04255194PS00022
DomainVWFD

MUC2 MUC5B

1.17e-0416192PS51233
DomainVWD

MUC2 MUC5B

1.17e-0416192SM00216
DomainVWF_type-D

MUC2 MUC5B

1.17e-0416192IPR001846
DomainVWD

MUC2 MUC5B

1.17e-0416192PF00094
DomainEGF-like_CS

MEGF9 MUC3A MUC3B MUC12

1.22e-04261194IPR013032
DomainEGF_2

MEGF9 MUC3A MUC3B MUC12

1.30e-04265194PS01186
DomainCTCK_1

MUC2 MUC5B

1.49e-0418192PS01185
DomainVWC_out

MUC2 MUC5B

1.66e-0419192SM00215
DomainCT

MUC2 MUC5B

2.24e-0422192SM00041
DomainCys_knot_C

MUC2 MUC5B

2.90e-0425192IPR006207
DomainCTCK_2

MUC2 MUC5B

2.90e-0425192PS01225
Domain-

INPP5J PDE12

3.14e-04261923.60.10.10
DomainExo_endo_phos

INPP5J PDE12

3.14e-0426192PF03372
DomainEndo/exonuclease/phosphatase

INPP5J PDE12

3.39e-0427192IPR005135
DomainVWFC_1

MUC2 MUC5B

6.05e-0436192PS01208
DomainVWC

MUC2 MUC5B

6.74e-0438192SM00214
DomainVWFC_2

MUC2 MUC5B

6.74e-0438192PS50184
DomainVWF_dom

MUC2 MUC5B

8.24e-0442192IPR001007
DomainEGF

MEGF9 MUC3A MUC3B

1.64e-03235193SM00181
DomainEGF-like_dom

MEGF9 MUC3A MUC3B

1.94e-03249193IPR000742
DomainLeu-rich_rpt_typical-subtyp

LRFN5 PHLPP2

1.37e-02177192IPR003591
DomainLRR_TYP

LRFN5 PHLPP2

1.37e-02177192SM00369
DomainLRR

LRFN5 PHLPP2

1.75e-02201192PS51450
DomainLRR_1

LRFN5 PHLPP2

2.05e-02219192PF00560
DomainEGF_3

MUC3A MUC3B

2.34e-02235192PS50026
DomainANK_REPEAT

ANKHD1 MUC16

2.69e-02253192PS50088
DomainANK_REP_REGION

ANKHD1 MUC16

2.71e-02254192PS50297
DomainLeu-rich_rpt

LRFN5 PHLPP2

3.05e-02271192IPR001611
PathwayREACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC

MUC16 MUC3A MUC5B MUC12

5.45e-1016124M27410
PathwayREACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS

MUC16 MUC3A MUC5B MUC12

7.12e-1017124M27412
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC16 MUC3A MUC5B MUC12

2.64e-0923124M556
PathwayREACTOME_DECTIN_2_FAMILY

MUC16 MUC3A MUC5B MUC12

4.45e-0926124M27483
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC16 MUC3A MUC5B MUC12

1.64e-0762124M546
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

MUC16 MUC3A MUC5B MUC12

2.38e-0768124M27303
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC2 MUC16 MUC5B

6.21e-0721123MM15706
PathwayREACTOME_O_LINKED_GLYCOSYLATION

MUC16 MUC3A MUC5B MUC12

1.72e-06111124M27416
PathwayREACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS

MUC16 MUC3A MUC5B MUC12

4.34e-06140124M27484
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

MUC16 MUC3A MUC5B MUC12

4.72e-06143124M27275
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC2 MUC16 MUC5B

1.57e-0560123MM15636
PathwayREACTOME_DISEASES_OF_METABOLISM

MUC16 MUC3A MUC5B MUC12

4.27e-05250124M27554
PathwayREACTOME_O_LINKED_GLYCOSYLATION

MUC2 MUC16 MUC5B

9.40e-05109123MM15164
PathwayREACTOME_INNATE_IMMUNE_SYSTEM

MUC16 MUC3A MUC5B MUC12

1.20e-021128124M1036
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC2 MUC16 MUC3A MUC5B MUC12

3.12e-131820518834073
Pubmed

Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.

MUC2 MUC16 MUC5B

3.25e-09620319110483
Pubmed

MUC3 human intestinal mucin. Analysis of gene structure, the carboxyl terminus, and a novel upstream repetitive region.

MUC3A MUC3B

3.14e-0722029334251
Pubmed

[Interleukin-1beta induces MUC2/MUC5B gene expression in human nasal epithelial cells].

MUC2 MUC5B

3.14e-07220220873538
Pubmed

Initiation of transcription of the MUC3A human intestinal mucin from a TATA-less promoter and comparison with the MUC3B amino terminus.

MUC3A MUC3B

3.14e-07220212958310
Pubmed

Molecular cloning of cDNAs derived from a novel human intestinal mucin gene.

MUC3A MUC3B

3.14e-0722022393399
Pubmed

Associations of distinct variants of the intestinal mucin gene MUC3A with ulcerative colitis and Crohn's disease.

MUC3A MUC3B

3.14e-07220211289722
Pubmed

Multiple transcripts of MUC3: evidence for two genes, MUC3A and MUC3B.

MUC3A MUC3B

3.14e-07220210973822
Pubmed

The MUC3 gene encodes a transmembrane mucin and is alternatively spliced.

MUC3A MUC3B

3.14e-07220210405327
Pubmed

Expression of mucin 3 and mucin 5AC in arthritic synovial tissue.

MUC3A MUC3B

9.42e-07320218163520
Pubmed

Differential Expression of MUC12, MUC16, and MUC20 in Patients with Active and Remission Ulcerative Colitis.

MUC16 MUC12

9.42e-07320226770020
Pubmed

DUSP28 links regulation of Mucin 5B and Mucin 16 to migration and survival of AsPC-1 human pancreatic cancer cells.

MUC16 MUC5B

9.42e-07320227230679
Pubmed

Mucin gene polymorphisms in otitis media patients.

MUC2 MUC5B

9.42e-07320219718741
Pubmed

Genomic organization and structure of the 3' region of human MUC3: alternative splicing predicts membrane-bound and soluble forms of the mucin.

MUC3A MUC3B

9.42e-07320210512748
Pubmed

Polymorphisms in MUC1, MUC2, MUC5B and MUC6 genes are not associated with the risk of chronic atrophic gastritis.

MUC2 MUC5B

1.88e-06420221596555
Pubmed

Increased expression of MUC5AC and MUC5B promoting bacterial biofilm formation in chronic rhinosinusitis patients.

MUC2 MUC5B

1.88e-06420225638393
Pubmed

Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.

MUC2 MUC5B

1.88e-06420217471237
Pubmed

Expression of MUC1, MUC2, MUC5AC and MUC5B in mucinous lesions of the breast.

MUC2 MUC5B

1.88e-06420222269464
Pubmed

The mouse secreted gel-forming mucin gene cluster.

MUC2 MUC5B

1.88e-06420214984930
Pubmed

Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.

MUC2 MUC5B

1.88e-06420212676567
Pubmed

Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.

MUC2 MUC5B

1.88e-06420223807779
Pubmed

Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.

MUC2 MUC5B

1.88e-06420229869461
Pubmed

Polymorphism of human mucin genes in chest disease: possible significance of MUC2.

MUC2 MUC5B

3.14e-06520211062147
Pubmed

Comprehensive glycomics comparison between colon cancer cell cultures and tumours: implications for biomarker studies.

MUC2 MUC5B

3.14e-06520224840470
Pubmed

Differential expression of MUC genes in endometrial and cervical tissues and tumors.

MUC2 MUC5B

3.14e-06520216188033
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

KDM3B MUC2 MUC16 MUC3A NFIC

1.26e-0555220510737800
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

MUC16 MUC5B PDE12

1.23e-0417020323314748
Pubmed

Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.

MUC2 MUC5B

2.54e-044120222675208
Pubmed

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.

KDM3B TMEM108

3.20e-044620221102462
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

KDM3B CHAMP1 NFIC

4.68e-0426820333640491
Cytoband7q22

MUC3A MUC3B MUC12

5.91e-07382037q22
CytobandEnsembl 112 genes in cytogenetic band chr7q22

PILRB MUC3A MUC12

1.15e-04219203chr7q22
Cytoband11p15.5

MUC2 MUC5B

1.21e-0311820211p15.5
CytobandEnsembl 112 genes in cytogenetic band chr5q31

ANKHD1 KDM3B

7.39e-03298202chr5q31
CytobandEnsembl 112 genes in cytogenetic band chr11p15

MUC2 MUC5B

2.47e-02564202chr11p15
GeneFamilyCD molecules|Mucins

MUC2 MUC16 MUC3A MUC5B MUC3B MUC12

3.34e-1521146648
CoexpressionNABA_ECM_AFFILIATED

MUC2 MUC16 MUC3A MUC5B MUC12

1.17e-07170195M5880
CoexpressionNABA_MATRISOME_ASSOCIATED

MEGF9 MUC2 MUC16 MUC3A MUC5B MUC12

1.07e-05751196M5885
CoexpressionNABA_MATRISOME

MEGF9 MUC2 MUC16 MUC3A MUC5B MUC12

6.20e-051026196M5889
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MUC16 LRFN5 TMEM108

2.53e-0513619388b5c839d0446c6d6b7e81fc4d48f5e7e96eea11
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MUC16 LRFN5 TMEM108

2.53e-0513619327a41463e6f16deb5b1d4f17fefded9959038c07
ToppCellnormal_Lymph_Node-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

ANKHD1 PILRB PDE12

5.26e-051741932274648b80dd74f3c948a779bba3391095964c34
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet-BEST2+_Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC2 MUC5B MUC12

5.35e-05175193019ea30ac55748463d7917abf3d3f0e804189bfd
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC2 MUC5B MUC12

5.63e-051781939099b47e0756d6a1b7ba1c6aa7b47c5425f649e0
ToppCellnucseq-Epithelial-Epithelial_Glandular|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 MUC3A MUC5B

5.73e-05179193859cd8ee414ad6207c046ada2e655e49322dd01c
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 MUC3A MUC5B

5.82e-051801933dc80bc636bf0e6ffc9762853132a9fe59fd1f66
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 MUC3A MUC5B

5.82e-05180193668a2d8e1d5a390309d5eb62c836f5903144bea9
ToppCellControl-Epithelial_cells-Airway_mucous|Control / group, cell type (main and fine annotations)

MUC16 MUC3A MUC5B

6.11e-0518319315d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCellControl-Epithelial_cells-Airway_goblet|Control / group, cell type (main and fine annotations)

MUC16 MUC3A MUC5B

6.21e-05184193d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

APBB2 TMEM108 INPP5J

6.62e-05188193bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCell5'-Adult-LargeIntestine|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC2 MUC5B MUC12

7.38e-05195193600174e35574fe7c44dd923adcf43686e7b01e39
ToppCell5'-GW_trimst-2-LargeIntestine|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC2 MUC5B MUC12

7.38e-051951931a4a5623fa0318ef388cc228c7060e0586a7acf9
ToppCelldistal-Epithelial-Goblet|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC2 MUC16 MUC5B

7.61e-05197193da1ed7303cc9cb2d205c0e5c49c52544d3540951
ToppCelldistal-3-Epithelial-Goblet|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC2 MUC16 MUC5B

7.61e-05197193a00784ccfb1de6a96b91e2a8a2889b69f31a33da
ToppCelldistal-Epithelial-Goblet-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC2 MUC16 MUC5B

7.61e-051971933fbf456ae4f73da4f6254a6f0d24f0ec27d7a3cc
ToppCellBL-critical-LOC-Epithelial-Secretory_LYPD2|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MUC2 MUC16 MUC5B

7.72e-05198193484d16aaa601a1e11b871b0475dd01a2de1a29ce
ToppCellBronchial-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Mucous|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 MUC5B INPP5J

7.84e-05199193eb2d1b7e875c5bf833e7a80b43282e12893c34e9
ToppCell5'-Adult|5' / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC3A MUC5B MUC12

7.84e-051991938b7b1fcea9a06522fdfab85d0dfd33010ae96d75
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Pvrl3-Excitatory_Neuron.Slc17a7.Pvrl3-Inhba_(CA3_Principal_cells)|Hippocampus / BrainAtlas - Mouse McCarroll V32

MUC2 POM121L2

4.48e-047419229d94713d97ac44e0f83d2f3609a719650e20d0f
ToppCellParenchymal-10x5prime-Epithelial-Epi_submucosal-gland|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 MUC5B

9.51e-0410819275d635fc5bb004418db2e1328c24d96b718f10b1
ToppCellParenchymal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Duct|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 MUC5B

9.51e-041081929c7f3e25facfb54ef0be45044999bc36438bbea0
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l14|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MEGF9 KDM3B

1.10e-03116192f2bf9599040f43b5ea8724841d7b71c0a859c016
ToppCellPBMC-Mild-cDC_2|Mild / Compartment, Disease Groups and Clusters

TMEM108 PHLPP2

1.48e-03135192cb9d834f8301cf53f20e09c3f4cb6a148690196a
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Mucinous|TCGA-Stomach / Sample_Type by Project: Shred V9

MUC2 MUC12

1.52e-03137192291b4eeaf21ec951695621161dbc2de3e82ca993
ToppCellNS-critical-d_07-13-Epithelial-unknown_epithelial|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PILRB MUC16

1.61e-0314119233ad925ff7be3c682741a6328216a89f9d4033e9
ToppCellControl-Plasmablast|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MUC2 SEC14L1

1.70e-03145192fe68582f5a15b9714cb84fa32ac880e13cb69895
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

INPP5J MUC12

1.70e-031451929964d6d3769be2f35d86268fe044cecd1d5a1616
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Mucinous-3|TCGA-Stomach / Sample_Type by Project: Shred V9

MUC2 MUC12

1.77e-03148192c95a732163050cfb5d604c2a4c9eb1afa9f19a95
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRFN5 PHLPP2

1.80e-031491927e295b2b82dea0754e98f8cef788e2781e5d641f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRFN5 PHLPP2

1.80e-03149192b4f77dc5f9d08b249fe5cd9a0acf86308c528ef4
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM108 PHLPP2

1.82e-0315019247ea08d7609e1d2382bf56ef9e5c767e3597cf93
ToppCellfacs-Aorta-Heart-3m-Epithelial|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC5B INPP5J

1.84e-03151192bee48137d1f5f27a24571a59c835284651d38538
ToppCellfacs-Aorta-Heart-3m-Epithelial-epithelial_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC5B INPP5J

1.84e-031511920de76acd1b204345dce7f33be2a1ed9fbe9e6da0
ToppCellfacs-Aorta-Heart-3m-Epithelial-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC5B INPP5J

1.84e-0315119220b9c8fb966c5d62ff909cc4a4616b109b78cdca
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PILRB MUC3A

1.89e-0315319292a5307b8e4dcf9ee42134b4c0645f9d488df61a
ToppCell367C-Lymphocytic-ILC-ILC-3|367C / Donor, Lineage, Cell class and subclass (all cells)

ANKHD1 PDE12

1.89e-031531929d64aadbb4bb28469af1d728457b431e21577429
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

APBB2 TMEM108

1.89e-0315319261fe71e32fc9c8cad875bc087aad0b0ff680bf45
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 MUC5B

1.94e-0315519262b59cb32b12bd55b19e98786a866d788fc9e4bf
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 MUC5B

1.99e-03157192c43f2e1ea53b375a7432f17f87cfef3b2261003d
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 MUC5B

2.04e-0315919260b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRFN5 TMEM108

2.04e-031591929f6607e395bcca9cb1c83199bdbbaaa62a93938d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRFN5 TMEM108

2.04e-03159192c8b42ebc25ebcc450832096fbffaa5c5f5fe88e7
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MUC3A MUC5B

2.07e-031601921f4ee446436726c3d373f56d87dd80b6a12e8b9e
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MUC3A MUC5B

2.07e-03160192028b5261a1da832d52f66fb620db83e5fbbd874a
ToppCell367C-Lymphocytic-ILC-ILC-3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MUC12 PDE12

2.09e-031611928de421c61f4d5a6e05fdb20e4d230e2db98ee4d5
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MUC16 MUC5B

2.09e-031611922d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B INPP5J

2.09e-031611927c9d4410d7142a5f3a05418c994f69978c9ffa17
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

APBB2 INPP5J

2.12e-0316219236ddebe3bb172c992739353b7b049b2dde98b559
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_C|TCGA-Thymus / Sample_Type by Project: Shred V9

MUC16 INPP5J

2.14e-031631922dac87d15051151ccf193760ddd8b82534c3f922
ToppCell5'-Adult-Appendix-Epithelial-goblet|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC2 MUC3A

2.17e-03164192e83b632ac7e1dace946991ddfe1fbfbbffc3a88b
ToppCellAdult-Epithelial-lung_goblet_cell-D175|Adult / Lineage, Cell type, age group and donor

MUC16 MUC5B

2.17e-031641926e6aedb61f8e195d52e028fdda750a29bb14e57e
ToppCell5'-Adult-Appendix-Epithelial-goblet-BEST2+_Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC2 MUC3A

2.17e-0316419229da0175bd3808a5b3039a6161c764105608ef96
ToppCellPND14-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRFN5 MUC5B

2.19e-03165192baff639a7046fb5cacb70f341b6d24cef3519f8e
ToppCellPND14-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRFN5 MUC5B

2.19e-03165192dd4d36ff8efb89fee1fb4c48d1b8f46902119909
ToppCellPND14-Epithelial-Epithelial_Airway-Neurosecretory|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRFN5 MUC5B

2.19e-031651926fdce8b23736409a23884ef3918638ffc067a86f
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B INPP5J

2.22e-0316619260060b03f2abfa3cc08107ab5a9f578e60e4ae16
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B INPP5J

2.22e-03166192ec9161d388db5a257b8d125c14f9dd911d5d5d4a
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B INPP5J

2.22e-031661924586d6725403f879fc96f67be579022587ce1906
ToppCellTCGA-Colorectal|World / Sample_Type by Project: Shred V9

MUC2 MUC12

2.22e-03166192c018cd8c7a82251c67e3dc812d4d21e527a43456
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 MUC5B

2.25e-0316719231633899aae852873a4887e72c621474b0a51a33
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MUC16 TMEM108

2.25e-031671927abc785e688a384672d7fb5a62d32538fe7e5a51
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MUC16 TMEM108

2.25e-03167192d50311b1f66f143bae4c4cf50e2e9b13c85d6920
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC2 MUC5B

2.33e-031701922c5a1469e5743870e96e6c2cc92f0c5096b79f51
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC2 MUC5B

2.33e-031701929bea81031cdfe45e8cddac3a3afd9ca6c331c45a
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B INPP5J

2.35e-03171192eddc5e05003382603ee49f74b9e2242a43021096
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC3A MUC5B

2.35e-031711923a2fefcb62e9d47ae6b3a946c45d3f2dd32c576c
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC3A MUC5B

2.35e-031711923ef44a5e3e8f81424f1e9aa302860b6688a549b8
ToppCell3'-Adult-Distal_Rectal-Epithelial-Tuft-related-BEST4+_epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHAMP1 MUC12

2.35e-03171192317b70d72a4ca5336cfb6a49dc57f8e2a8a1c736
ToppCell5'-Adult-LargeIntestine-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC2 MUC5B

2.35e-0317119248125d825ca2d7ef34564250f5b47d2a579e03c9
ToppCellP07-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MUC16 TMEM108

2.38e-031721929a256db817c1af1802203cc88a55d608fb328c63
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

MUC16 MUC5B

2.41e-03173192d1e47c87bd4750801f3531f66a56c5dccb4ea64c
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MUC16 TMEM108

2.41e-031731923725525b99a6011eda2ff5459b4fd2e1eab1f090
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 MUC5B

2.41e-031731923aa1d28d4814798a772808ed29e1dbbdf92abd03
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MUC16 MUC5B

2.41e-03173192464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MUC16 TMEM108

2.41e-03173192ee7d1429f23f1b89a9a9f7bc07a84a44cf7acd1c
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 MUC5B

2.41e-03173192e8afef5ae68983eb8d6515b43952636a47e9d3d4
ToppCellAT1_cells-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

APBB2 MEGF9

2.41e-03173192b29816427428c7053017477f59b828bf1357f3b2
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

APBB2 POM121L2

2.44e-0317419240bb87d219aafab0357ab0d797efd38085fc0312
ToppCellAdult-Epithelial-lung_goblet_cell-D231|Adult / Lineage, Cell type, age group and donor

MUC16 MUC5B

2.44e-031741927d2f802f493f19a068e097b2909a9000e2160266
ToppCell(03)_Secretory-(0)_uninjured|(03)_Secretory / shred by cell type and Timepoint

MUC16 MUC5B

2.44e-03174192ebdddb5091afcc49ab533c890f260f709880c5f9
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 MUC3A

2.44e-03174192207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MUC3A MUC5B

2.46e-0317519219eda8b5d39dc93d79737ebdbeeba5ec0cb23c51
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 MUC5B

2.49e-03176192dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCell(03)_Secretory|World / shred by cell type and Timepoint

MUC16 MUC5B

2.49e-03176192cb7b1945788196ca79007f0768b6576ec885a0e5
ToppCellnormal_Lymph_Node-Myeloid_cells-pDCs|normal_Lymph_Node / Location, Cell class and cell subclass

ANKHD1 PDE12

2.49e-03176192476794ef75ce5ab732d78cfeb4944e2f841e3e92
ToppCellAT1_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

APBB2 MUC3A

2.49e-03176192458720776b0151cd55acc352d509599cb62f0ca8
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC2 MUC12

2.52e-03177192e1e45956887371b1c18f1eb479dd930031497520
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

APBB2 SEC14L1

2.52e-031771921921226196b2ab7919d9f843e60d9f4bd9ec9c57
ToppCellFetal_29-31_weeks-Epithelial-lung_goblet_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MUC16 MUC5B

2.52e-03177192a4c001a8e44142babf9f24dfe6f7b73a70b11b16
ToppCellFetal_29-31_weeks-Epithelial-lung_goblet_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MUC16 MUC5B

2.52e-03177192363e07b0f347f3716d530a28ead854b98e27d37c
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MUC16 TMEM108

2.55e-03178192c413861148129be1ee94f2ceb5999840217eebe5
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-respiratory_basal_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM108 MUC5B

2.55e-03178192fb8f8d95f6b08378fb42c4076ee040276faa296f
ToppCellBAL-Severe-Epithelial-Epithelial-undefined_Epi-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MUC16 MUC5B

2.55e-031781929a3ef66814dfca7b37024e7f79e86ea8c72ae10f
ToppCellBAL-Severe-Epithelial-Epithelial-undefined_Epi|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

MUC16 MUC5B

2.55e-0317819219b5432aa1d7f616d58a106543c18cf2d7ca840c
ToppCellBAL-Severe-Epithelial-Epithelial-undefined_Epi|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MUC16 MUC5B

2.55e-0317819249a2271718637522f74334068d252963ee13b1ce
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC16 SEC14L1

2.55e-03178192360d7a987f91d6d721487a921824057ec31a7332
ToppCell390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|390C / Donor, Lineage, Cell class and subclass (all cells)

MUC16 MUC5B

2.55e-03178192fce60ce6b662f1bdaa3b4da43800c6c22fe89533
ToppCell(5)_Glands_mucous|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

MUC16 MUC5B

2.55e-03178192f0f19b0d78f2cc5df4d4c321a953a6e447d5114a
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MUC16 TMEM108

2.55e-031781921e05bc26591fea16e29bcfc5f538dda1dc427f05
Drugrioprostil

MUC3A MUC3B MUC12

2.83e-0632203CID005311413
Drugcellobiitol

MUC3A MUC3B MUC12

4.42e-0637203CID000003871
DrugGastrin tetrapeptide

MUC3A MUC3B MUC12

1.11e-0550203CID000005415
DrugSertaconazole nitrate [99592-39-9]; Down 200; 8uM; HL60; HT_HG-U133A

APBB2 POM121L2 PDE12 SEC14L1

2.23e-051942046128_DN
DrugCyclopentolate hydrochloride [5870-29-1]; Down 200; 12.2uM; HL60; HT_HG-U133A

APBB2 PDE12 PHLPP2 SEC14L1

2.46e-051992046132_DN
Drugmucic acid

MUC3A MUC3B MUC12

6.06e-0588203CID000000607
Diseasecholangiocarcinoma (is_marker_for)

MUC2 MUC16 MUC3A MUC5B

9.50e-0864204DOID:4947 (is_marker_for)
Diseasealcohol dependence

MUC2 LRFN5 TMEM108

2.48e-04183203MONDO_0007079
Diseaseheart rate response to exercise

MUC3A MUC3B

3.88e-0443202EFO_0009184
Diseaseplasminogen activator inhibitor 1 measurement

NFIC MUC12

6.12e-0454202EFO_0004792
Diseasepancreatic ductal carcinoma (is_marker_for)

MUC3A MUC5B

7.80e-0461202DOID:3587 (is_marker_for)
Diseasecystic fibrosis (is_marker_for)

MUC2 MUC5B

8.05e-0462202DOID:1485 (is_marker_for)
Diseasetotal iron binding capacity

POM121L2 TMEM108

1.27e-0378202EFO_0006334
Diseaseeye color

APBB2 MUC16

1.69e-0390202EFO_0003949
DiseaseInhalant adrenergic use measurement

MUC2 MUC16

1.92e-0396202EFO_0009941
DiseaseRS-10-hydroxywarfarin to RS-warfarin ratio measurement

MUC3A MUC3B

2.50e-03110202EFO_0803335
Diseasebipolar I disorder

ANKHD1 KDM3B

4.07e-03141202EFO_0009963
Diseasebipolar disorder

ANKHD1 KDM3B TMEM108

6.62e-03577203MONDO_0004985
Diseaseobsessive-compulsive disorder, attention deficit hyperactivity disorder, Tourette syndrome, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia, anorexia nervosa

KDM3B LRFN5

8.02e-03200202EFO_0003756, EFO_0003761, EFO_0003888, EFO_0004242, EFO_0004895, MONDO_0004985, MONDO_0005090, MONDO_0005351

Protein segments in the cluster

PeptideGeneStartEntry
SWTTLSQDSASPSSP

APBB2

261

Q92870
TSSTATPSSTPGTTW

MUC5B

1891

Q9HC84
WISTTTTPTTRGSTV

MUC5B

2076

Q9HC84
PSSPHTVRTAWTSAT

MUC5B

2761

Q9HC84
PSSPHTVRTAWTSAT

MUC5B

3461

Q9HC84
TSSTSTPSSTPGTTW

MUC5B

4376

Q9HC84
TATSFTPIPSSTLWT

MUC5B

4746

Q9HC84
DSSTTTSALPPSWTS

LRFN5

621

Q96NI6
TSALPPSWTSSTSVS

LRFN5

626

Q96NI6
TTSLPTTTWPSTSLS

MUC16

2056

Q8WXI7
SVPDILSTSWTPSST

MUC16

3686

Q8WXI7
PSTNTVETTGWVTSS

MUC16

3946

Q8WXI7
TSWNTETSPSVTSVG

MUC16

11916

Q8WXI7
RSSGLTTSTPWTSTV

MUC16

13131

Q8WXI7
TTSTPWTSTVDLGTS

MUC16

13136

Q8WXI7
PSTVQTTTTSAWTPT

MUC2

4296

Q02817
RTTTSWPTATNTLSP

MUC3A

1401

Q02505
LSPSSPSSSWTETDV

PDE12

216

Q6L8Q7
SSATTVTSKVAPSWP

KDM3B

661

Q7LBC6
ETTPLWATAGPSSTT

MEGF9

101

Q9H1U4
PTPSVSSASWKSSSV

CHAMP1

361

Q96JM3
WSPPSITTSSETSSS

SEC14L1

181

Q92503
WSSTPTIIMSSSPSS

MUC3B

596

Q9H195
TSPSSPTSSSRNWTE

NFIC

301

P08651
LTPSASTSQTPASTW

POM121L2

831

Q96KW2
WTSASNSSTSAPPTL

ANKHD1

2336

Q8IWZ3
SSTSTLSSSPWSAQP

INPP5J

401

Q15735
PLPTTDSTVTSTFWS

PHLPP2

771

Q6ZVD8
QAVTTTTTWRPSSTT

PILRB

151

Q9UKJ0
TTVPSNTSWAPTTTS

TMEM108

256

Q6UXF1
TTFQSWPSSSDTTPS

MUC12

1581

Q9UKN1
TTFQSWPSSSDTTPS

MUC12

4221

Q9UKN1