Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	volume-sensitive anion channel activity	LRRC8E LRRC8C CLCN3 LRRC8A LRRC8B	1.00e-11	9	50	5	GO:0005225
GeneOntologyMolecularFunction	monoatomic anion transmembrane transporter activity	LRRC8E LRRC8C GABRR1 SLC4A7 CLCN3 ANO6 LRRC8A GABRQ LRRC8B	1.22e-10	151	50	9	GO:0008509
GeneOntologyMolecularFunction	monoatomic anion channel activity	LRRC8E LRRC8C GABRR1 CLCN3 ANO6 LRRC8A GABRQ LRRC8B	1.71e-10	103	50	8	GO:0005253
GeneOntologyMolecularFunction	monoatomic ion channel activity	LRRC8E LRRC8C GABRR1 CACNA1E CLCN3 NALCN ANO6 LRRC8A GABRQ LRRC8B	1.68e-07	459	50	10	GO:0005216
GeneOntologyMolecularFunction	transporter activity	LRRC8E LRRC8C GABRR1 CACNA1E SLC4A7 ATP8A1 CLCN3 SLC7A13 NALCN ANO6 NPC1L1 LRRC8A GABRQ LRRC8B ATP10D	3.41e-07	1289	50	15	GO:0005215
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	LRRC8E LRRC8C GABRR1 CACNA1E SLC4A7 ATP8A1 CLCN3 NALCN ANO6 LRRC8A GABRQ LRRC8B	4.28e-07	793	50	12	GO:0015075
GeneOntologyMolecularFunction	channel activity	LRRC8E LRRC8C GABRR1 CACNA1E CLCN3 NALCN ANO6 LRRC8A GABRQ LRRC8B	5.79e-07	525	50	10	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	LRRC8E LRRC8C GABRR1 CACNA1E CLCN3 NALCN ANO6 LRRC8A GABRQ LRRC8B	5.89e-07	526	50	10	GO:0022803
GeneOntologyMolecularFunction	transmembrane transporter activity	LRRC8E LRRC8C GABRR1 CACNA1E SLC4A7 ATP8A1 CLCN3 SLC7A13 NALCN ANO6 LRRC8A GABRQ LRRC8B	4.58e-06	1180	50	13	GO:0022857
GeneOntologyMolecularFunction	chloride channel activity	GABRR1 CLCN3 ANO6 GABRQ	6.35e-05	86	50	4	GO:0005254
GeneOntologyMolecularFunction	inorganic anion transmembrane transporter activity	GABRR1 SLC4A7 CLCN3 ANO6 GABRQ	6.74e-05	171	50	5	GO:0015103
GeneOntologyMolecularFunction	signal recognition particle binding	DERL3 DERL2	1.70e-04	8	50	2	GO:0005047
GeneOntologyMolecularFunction	ligand-gated monoatomic anion channel activity	GABRR1 ANO6 GABRQ	2.67e-04	50	50	3	GO:0099095
GeneOntologyMolecularFunction	chloride transmembrane transporter activity	GABRR1 CLCN3 ANO6 GABRQ	2.70e-04	125	50	4	GO:0015108
GeneOntologyMolecularFunction	intramembrane lipid transporter activity	ATP8A1 ANO6 ATP10D	2.83e-04	51	50	3	GO:0140303
GeneOntologyMolecularFunction	voltage-gated chloride channel activity	CLCN3 ANO6	3.33e-04	11	50	2	GO:0005247
GeneOntologyMolecularFunction	protein phosphatase activator activity	PPP2R5A PPP2R5C	8.16e-04	17	50	2	GO:0072542
GeneOntologyMolecularFunction	voltage-gated monoatomic anion channel activity	CLCN3 ANO6	8.16e-04	17	50	2	GO:0008308
GeneOntologyMolecularFunction	flippase activity	ATP8A1 ATP10D	8.16e-04	17	50	2	GO:0140327
GeneOntologyMolecularFunction	GABA-gated chloride ion channel activity	GABRR1 GABRQ	9.16e-04	18	50	2	GO:0022851
GeneOntologyMolecularFunction	GABA-A receptor activity	GABRR1 GABRQ	1.02e-03	19	50	2	GO:0004890
GeneOntologyMolecularFunction	phosphatase activator activity	PPP2R5A PPP2R5C	1.13e-03	20	50	2	GO:0019211
GeneOntologyMolecularFunction	GABA receptor activity	GABRR1 GABRQ	1.37e-03	22	50	2	GO:0016917
GeneOntologyMolecularFunction	gated channel activity	GABRR1 CACNA1E CLCN3 ANO6 GABRQ	1.45e-03	334	50	5	GO:0022836
GeneOntologyMolecularFunction	lipid transporter activity	ATP8A1 ANO6 NPC1L1 ATP10D	1.46e-03	196	50	4	GO:0005319
GeneOntologyMolecularFunction	ATPase-coupled intramembrane lipid transporter activity	ATP8A1 ATP10D	2.23e-03	28	50	2	GO:0140326
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	GABRR1 CACNA1E SLC4A7 CLCN3 NALCN ANO6 GABRQ	2.66e-03	758	50	7	GO:0015318
GeneOntologyMolecularFunction	antiporter activity	SLC4A7 CLCN3 SLC7A13	4.99e-03	138	50	3	GO:0015297
GeneOntologyBiologicalProcess	monoatomic anion transmembrane transport	LRRC8E LRRC8C GABRR1 SLC4A7 CLCN3 ANO6 LRRC8A GABRQ LRRC8B	1.04e-10	153	50	9	GO:0098656
GeneOntologyBiologicalProcess	monoatomic anion transport	LRRC8E LRRC8C GABRR1 SLC4A7 CLCN3 ANO6 LRRC8A GABRQ LRRC8B	5.12e-10	183	50	9	GO:0006820
GeneOntologyBiologicalProcess	aspartate transmembrane transport	LRRC8E LRRC8C SLC7A13 LRRC8A LRRC8B	1.74e-09	22	50	5	GO:0015810
GeneOntologyBiologicalProcess	cyclic-GMP-AMP transmembrane import across plasma membrane	LRRC8E LRRC8C LRRC8A LRRC8B	2.12e-09	8	50	4	GO:0140361
GeneOntologyBiologicalProcess	guanine nucleotide transmembrane transport	LRRC8E LRRC8C LRRC8A LRRC8B	6.35e-09	10	50	4	GO:1903790
GeneOntologyBiologicalProcess	C4-dicarboxylate transport	LRRC8E LRRC8C SLC7A13 LRRC8A LRRC8B	7.75e-09	29	50	5	GO:0015740
GeneOntologyBiologicalProcess	cyclic nucleotide transport	LRRC8E LRRC8C LRRC8A LRRC8B	9.96e-09	11	50	4	GO:0070729
GeneOntologyBiologicalProcess	guanine nucleotide transport	LRRC8E LRRC8C LRRC8A LRRC8B	9.96e-09	11	50	4	GO:0001408
GeneOntologyBiologicalProcess	organophosphate ester transport	LRRC8E LRRC8C ATP8A1 ANO6 LRRC8A LRRC8B ATP10D	1.22e-07	162	50	7	GO:0015748
GeneOntologyBiologicalProcess	nucleotide transmembrane transport	LRRC8E LRRC8C LRRC8A LRRC8B	9.16e-07	31	50	4	GO:1901679
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	LRRC8E LRRC8C GABRR1 CACNA1E SLC4A7 ATP8A1 CLCN3 NALCN ANO6 LRRC8A GABRQ LRRC8B ATP10D	1.71e-06	1115	50	13	GO:0034220
GeneOntologyBiologicalProcess	purine-containing compound transmembrane transport	LRRC8E LRRC8C LRRC8A LRRC8B	2.62e-06	40	50	4	GO:0072530
GeneOntologyBiologicalProcess	purine ribonucleotide transport	LRRC8E LRRC8C LRRC8A LRRC8B	2.62e-06	40	50	4	GO:0015868
GeneOntologyBiologicalProcess	monoatomic ion transport	LRRC8E LRRC8C GABRR1 CACNA1E SLC4A7 ATP8A1 CLCN3 NALCN ANO6 LRRC8A GABRQ TACR2 LRRC8B ATP10D	3.06e-06	1374	50	14	GO:0006811
GeneOntologyBiologicalProcess	cell volume homeostasis	LRRC8E CLCN3 ANO6 LRRC8A	3.19e-06	42	50	4	GO:0006884
GeneOntologyBiologicalProcess	adenine nucleotide transport	LRRC8E LRRC8C LRRC8A LRRC8B	3.19e-06	42	50	4	GO:0051503
GeneOntologyBiologicalProcess	purine nucleotide transport	LRRC8E LRRC8C LRRC8A LRRC8B	3.86e-06	44	50	4	GO:0015865
GeneOntologyBiologicalProcess	inorganic anion transport	GABRR1 SLC4A7 CLCN3 ANO6 LRRC8A GABRQ	4.70e-06	180	50	6	GO:0015698
GeneOntologyBiologicalProcess	nucleotide transport	LRRC8E LRRC8C LRRC8A LRRC8B	6.48e-06	50	50	4	GO:0006862
GeneOntologyBiologicalProcess	import into cell	LRRC8E LRRC8C CACNA1E ATP8A1 DENND1B CLCN3 ANO6 LRRC8A LRRC8B FER1L5 DENND1A SORL1	7.21e-06	1074	50	12	GO:0098657
GeneOntologyBiologicalProcess	chloride transmembrane transport	GABRR1 CLCN3 ANO6 LRRC8A GABRQ	7.52e-06	112	50	5	GO:1902476
GeneOntologyBiologicalProcess	amino acid transmembrane transport	LRRC8E LRRC8C SLC7A13 LRRC8A LRRC8B	1.05e-05	120	50	5	GO:0003333
GeneOntologyBiologicalProcess	dicarboxylic acid transport	LRRC8E LRRC8C SLC7A13 LRRC8A LRRC8B	1.05e-05	120	50	5	GO:0006835
GeneOntologyBiologicalProcess	chloride transport	GABRR1 CLCN3 ANO6 LRRC8A GABRQ	1.44e-05	128	50	5	GO:0006821
GeneOntologyBiologicalProcess	inorganic anion transmembrane transport	GABRR1 CLCN3 ANO6 LRRC8A GABRQ	1.80e-05	134	50	5	GO:0098661
GeneOntologyBiologicalProcess	regulation of protein exit from endoplasmic reticulum	DERL3 DERL2 SORL1	3.76e-05	27	50	3	GO:0070861
GeneOntologyBiologicalProcess	carboxylic acid transmembrane transport	LRRC8E LRRC8C SLC7A13 LRRC8A LRRC8B	4.61e-05	163	50	5	GO:1905039
GeneOntologyBiologicalProcess	organic acid transmembrane transport	LRRC8E LRRC8C SLC7A13 LRRC8A LRRC8B	5.17e-05	167	50	5	GO:1903825
GeneOntologyBiologicalProcess	carbohydrate derivative transport	LRRC8E LRRC8C LRRC8A LRRC8B	8.61e-05	96	50	4	GO:1901264
GeneOntologyBiologicalProcess	amino acid transport	LRRC8E LRRC8C SLC7A13 LRRC8A LRRC8B	1.08e-04	195	50	5	GO:0006865
GeneOntologyBiologicalProcess	alkanesulfonate transmembrane transport	LRRC8C LRRC8A	1.60e-04	8	50	2	GO:0042918
GeneOntologyBiologicalProcess	negative regulation of cell volume	CLCN3 ANO6	1.60e-04	8	50	2	GO:0045794
GeneOntologyBiologicalProcess	taurine transmembrane transport	LRRC8C LRRC8A	1.60e-04	8	50	2	GO:0015734
GeneOntologyBiologicalProcess	protein hexamerization	LRRC8C LRRC8A	2.05e-04	9	50	2	GO:0034214
GeneOntologyBiologicalProcess	negative regulation of retrograde protein transport, ER to cytosol	DERL3 DERL2	2.05e-04	9	50	2	GO:1904153
GeneOntologyBiologicalProcess	import across plasma membrane	LRRC8E LRRC8C CACNA1E LRRC8A LRRC8B	2.32e-04	230	50	5	GO:0098739
GeneOntologyBiologicalProcess	negative regulation of protein exit from endoplasmic reticulum	DERL3 DERL2	2.56e-04	10	50	2	GO:0070862
GeneOntologyBiologicalProcess	protein exit from endoplasmic reticulum	DERL3 DERL2 SORL1	2.57e-04	51	50	3	GO:0032527
GeneOntologyBiologicalProcess	regulation of lipid kinase activity	PPP2R5A RBL1	3.12e-04	11	50	2	GO:0043550
GeneOntologyBiologicalProcess	phospholipid translocation	ATP8A1 ANO6 ATP10D	3.22e-04	55	50	3	GO:0045332
GeneOntologyBiologicalProcess	positive regulation of synaptic transmission, cholinergic	NALCN TACR2	3.74e-04	12	50	2	GO:0032224
GeneOntologyBiologicalProcess	lipid translocation	ATP8A1 ANO6 ATP10D	4.16e-04	60	50	3	GO:0034204
GeneOntologyBiologicalProcess	regulation of retrograde protein transport, ER to cytosol	DERL3 DERL2	5.14e-04	14	50	2	GO:1904152
GeneOntologyBiologicalProcess	sulfur compound transport	LRRC8C SLC7A13 LRRC8A	5.27e-04	65	50	3	GO:0072348
GeneOntologyBiologicalProcess	regulation of membrane lipid distribution	ATP8A1 ANO6 ATP10D	5.27e-04	65	50	3	GO:0097035
GeneOntologyBiologicalProcess	regulation of synaptic transmission, cholinergic	NALCN TACR2	7.65e-04	17	50	2	GO:0032222
GeneOntologyBiologicalProcess	protein N-linked glycosylation	ALG14 DERL3 ST3GAL1	8.32e-04	76	50	3	GO:0006487
GeneOntologyBiologicalProcess	regulation of intracellular protein transport	PIK3R1 DERL3 DERL2 SORL1	9.84e-04	182	50	4	GO:0033157
GeneOntologyBiologicalProcess	endoplasmic reticulum unfolded protein response	PIK3R1 DERL3 DERL2	1.15e-03	85	50	3	GO:0030968
GeneOntologyBiologicalProcess	organic anion transport	LRRC8E LRRC8C SLC4A7 SLC7A13 LRRC8A LRRC8B	1.47e-03	515	50	6	GO:0015711
GeneOntologyBiologicalProcess	endocytic recycling	DENND1B DENND1A SORL1	1.59e-03	95	50	3	GO:0032456
GeneOntologyBiologicalProcess	cilium movement involved in cell motility	CACNA1E YIF1B TACR2 DNAH9	1.67e-03	210	50	4	GO:0060294
GeneOntologyBiologicalProcess	cilium or flagellum-dependent cell motility	CACNA1E YIF1B TACR2 DNAH9	1.82e-03	215	50	4	GO:0001539
GeneOntologyBiologicalProcess	cilium-dependent cell motility	CACNA1E YIF1B TACR2 DNAH9	1.82e-03	215	50	4	GO:0060285
GeneOntologyBiologicalProcess	cellular response to unfolded protein	PIK3R1 DERL3 DERL2	1.84e-03	100	50	3	GO:0034620
GeneOntologyCellularComponent	transporter complex	LRRC8E LRRC8C GABRR1 CACNA1E ATP8A1 NALCN ANO6 LRRC8A GABRQ LRRC8B ATP10D	5.58e-08	550	50	11	GO:1990351
GeneOntologyCellularComponent	endoplasmic reticulum membrane	LRRC8E LRRC8C YIF1B PIK3R1 ALG14 DERL3 DERL2 LRRC8B FADS2B ZDHHC11 REEP3 HACD1 AWAT1 ATP10D SORL1	1.97e-07	1293	50	15	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	LRRC8E LRRC8C YIF1B PIK3R1 ALG14 DERL3 DERL2 LRRC8B FADS2B ZDHHC11 REEP3 HACD1 AWAT1 ATP10D SORL1	2.09e-07	1299	50	15	GO:0098827
GeneOntologyCellularComponent	monoatomic ion channel complex	LRRC8E LRRC8C GABRR1 CACNA1E NALCN ANO6 LRRC8A GABRQ LRRC8B	2.45e-07	378	50	9	GO:0034702
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	LRRC8E LRRC8C YIF1B PIK3R1 ALG14 DERL3 DERL2 LRRC8B FADS2B ZDHHC11 REEP3 HACD1 AWAT1 ATP10D SORL1	2.76e-07	1327	50	15	GO:0042175
GeneOntologyCellularComponent	transmembrane transporter complex	LRRC8E LRRC8C GABRR1 CACNA1E NALCN ANO6 LRRC8A GABRQ LRRC8B	3.61e-06	523	50	9	GO:1902495
GeneOntologyCellularComponent	chloride channel complex	GABRR1 ANO6 GABRQ	3.44e-04	57	50	3	GO:0034707
GeneOntologyCellularComponent	phospholipid-translocating ATPase complex	ATP8A1 ATP10D	5.01e-04	14	50	2	GO:1990531
GeneOntologyCellularComponent	membrane protein complex	LRRC8E LRRC8C GABRR1 CACNA1E NALCN ANO6 PIK3R1 ALG14 LRRC8A GABRQ LRRC8B	6.83e-04	1498	50	11	GO:0098796
GeneOntologyCellularComponent	trans-Golgi network	ATP8A1 FAM91A1 ST3GAL1 CLVS1 SORL1	8.04e-04	306	50	5	GO:0005802
GeneOntologyCellularComponent	protein phosphatase type 2A complex	PPP2R5A PPP2R5C	8.37e-04	18	50	2	GO:0000159
GeneOntologyCellularComponent	GABA-A receptor complex	GABRR1 GABRQ	9.34e-04	19	50	2	GO:1902711
GeneOntologyCellularComponent	GABA receptor complex	GABRR1 GABRQ	1.14e-03	21	50	2	GO:1902710
GeneOntologyCellularComponent	synaptic membrane	GABRR1 CACNA1E CLCN3 ANO6 GABRQ DENND1A	2.57e-03	583	50	6	GO:0097060
GeneOntologyCellularComponent	sno(s)RNA-containing ribonucleoprotein complex	POP4 NOP56	2.66e-03	32	50	2	GO:0005732
GeneOntologyCellularComponent	cytoplasmic vesicle membrane	ATP8A1 CLCN3 ANO6 NPC1L1 ZDHHC11 FER1L5 DENND1A CLVS1 SORL1	3.48e-03	1307	50	9	GO:0030659
GeneOntologyCellularComponent	vesicle membrane	ATP8A1 CLCN3 ANO6 NPC1L1 ZDHHC11 FER1L5 DENND1A CLVS1 SORL1	3.81e-03	1325	50	9	GO:0012506
GeneOntologyCellularComponent	Golgi apparatus subcompartment	ATP8A1 FAM91A1 ST3GAL1 CLVS1 SORL1	4.04e-03	443	50	5	GO:0098791
GeneOntologyCellularComponent	transport vesicle membrane	ATP8A1 CLCN3 FER1L5 SORL1	5.25e-03	293	50	4	GO:0030658
Domain	LRRC8_Pannexin-like	LRRC8E LRRC8C LRRC8A LRRC8B	2.09e-10	5	49	4	IPR021040
Domain	Pannexin_like	LRRC8E LRRC8C LRRC8A LRRC8B	2.09e-10	5	49	4	PF12534
Domain	DER1	DERL3 DERL2	2.02e-05	3	49	2	IPR007599
Domain	PP2A_B56	PPP2R5A PPP2R5C	6.71e-05	5	49	2	IPR002554
Domain	B56	PPP2R5A PPP2R5C	6.71e-05	5	49	2	PF01603
Domain	LRR_5	LRRC8C LRRC8B	2.99e-04	10	49	2	PF13306
Domain	LRR_5	LRRC8C LRRC8B	2.99e-04	10	49	2	IPR026906
Domain	P_typ_ATPase_c	ATP8A1 ATP10D	6.01e-04	14	49	2	IPR032630
Domain	P-type_ATPase_N	ATP8A1 ATP10D	6.01e-04	14	49	2	IPR032631
Domain	P-type_ATPase_IV	ATP8A1 ATP10D	6.01e-04	14	49	2	IPR006539
Domain	PhoLip_ATPase_C	ATP8A1 ATP10D	6.01e-04	14	49	2	PF16212
Domain	PhoLip_ATPase_N	ATP8A1 ATP10D	6.01e-04	14	49	2	PF16209
Domain	uDENN	DENND1B DENND1A	6.01e-04	14	49	2	SM00800
Domain	uDENN	DENND1B DENND1A	6.93e-04	15	49	2	PF03456
Domain	DENN	DENND1B DENND1A	7.90e-04	16	49	2	PF02141
Domain	UDENN	DENND1B DENND1A	7.90e-04	16	49	2	PS50946
Domain	DDENN	DENND1B DENND1A	7.90e-04	16	49	2	PS50947
Domain	dDENN_dom	DENND1B DENND1A	7.90e-04	16	49	2	IPR005112
Domain	uDENN_dom	DENND1B DENND1A	7.90e-04	16	49	2	IPR005113
Domain	dDENN	DENND1B DENND1A	7.90e-04	16	49	2	PF03455
Domain	DENN	DENND1B DENND1A	7.90e-04	16	49	2	SM00799
Domain	DENN	DENND1B DENND1A	7.90e-04	16	49	2	PS50211
Domain	DENN_dom	DENND1B DENND1A	7.90e-04	16	49	2	IPR001194
Domain	dDENN	DENND1B DENND1A	7.90e-04	16	49	2	SM00801
Domain	LRR_8	LRRC8E LRRC8C LRRC8A LRRC8B	1.04e-03	171	49	4	PF13855
Domain	Leu-rich_rpt_typical-subtyp	LRRC8E LRRC8C LRRC8A LRRC8B	1.18e-03	177	49	4	IPR003591
Domain	LRR_TYP	LRRC8E LRRC8C LRRC8A LRRC8B	1.18e-03	177	49	4	SM00369
Domain	GABAA/Glycine_rcpt	GABRR1 GABRQ	1.65e-03	23	49	2	IPR006028
Domain	LRR	LRRC8E LRRC8C LRRC8A LRRC8B	1.89e-03	201	49	4	PS51450
Domain	LRR_1	LRRC8E LRRC8C LRRC8A LRRC8B	2.58e-03	219	49	4	PF00560
Domain	-	ATP8A1 ATP10D	3.18e-03	32	49	2	2.70.150.10
Domain	-	ATP8A1 ATP10D	3.18e-03	32	49	2	3.40.1110.10
Domain	ATPase_P-typ_cyto_domN	ATP8A1 ATP10D	3.80e-03	35	49	2	IPR023299
Domain	ATPase_P-typ_P_site	ATP8A1 ATP10D	4.01e-03	36	49	2	IPR018303
Domain	P_typ_ATPase	ATP8A1 ATP10D	4.01e-03	36	49	2	IPR001757
Domain	ATPASE_E1_E2	ATP8A1 ATP10D	4.01e-03	36	49	2	PS00154
Domain	ATPase_P-typ_transduc_dom_A	ATP8A1 ATP10D	4.24e-03	37	49	2	IPR008250
Domain	E1-E2_ATPase	ATP8A1 ATP10D	4.24e-03	37	49	2	PF00122
Domain	Leu-rich_rpt	LRRC8E LRRC8C LRRC8A LRRC8B	5.50e-03	271	49	4	IPR001611
Domain	Neurotransmitter_ion_chnl_CS	GABRR1 GABRQ	6.21e-03	45	49	2	IPR018000
Domain	TF_fork_head_CS_2	FOXN2 FOXN3	6.48e-03	46	49	2	IPR030456
Domain	Neur_chan_memb	GABRR1 GABRQ	6.48e-03	46	49	2	PF02932
Domain	Neur_chan_LBD	GABRR1 GABRQ	6.76e-03	47	49	2	PF02931
Domain	Neur_channel	GABRR1 GABRQ	6.76e-03	47	49	2	IPR006201
Domain	Neur_chan_lig-bd	GABRR1 GABRQ	6.76e-03	47	49	2	IPR006202
Domain	NEUROTR_ION_CHANNEL	GABRR1 GABRQ	6.76e-03	47	49	2	PS00236
Domain	Neurotrans-gated_channel_TM	GABRR1 GABRQ	6.76e-03	47	49	2	IPR006029
Domain	TF_fork_head_CS_1	FOXN2 FOXN3	6.76e-03	47	49	2	IPR018122
Domain	-	GABRR1 GABRQ	6.76e-03	47	49	2	2.70.170.10
Domain	FORK_HEAD_3	FOXN2 FOXN3	7.33e-03	49	49	2	PS50039
Domain	FH	FOXN2 FOXN3	7.33e-03	49	49	2	SM00339
Domain	FORK_HEAD_1	FOXN2 FOXN3	7.33e-03	49	49	2	PS00657
Domain	FORK_HEAD_2	FOXN2 FOXN3	7.33e-03	49	49	2	PS00658
Domain	Forkhead	FOXN2 FOXN3	7.33e-03	49	49	2	PF00250
Domain	Fork_head_dom	FOXN2 FOXN3	7.33e-03	49	49	2	IPR001766
Pathway	REACTOME_MISCELLANEOUS_TRANSPORT_AND_BINDING_EVENTS	LRRC8E LRRC8C LRRC8A LRRC8B	8.23e-07	25	42	4	MM15172
Pathway	REACTOME_MISCELLANEOUS_TRANSPORT_AND_BINDING_EVENTS	LRRC8E LRRC8C LRRC8A LRRC8B	9.70e-07	26	42	4	M27424
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	LRRC8E LRRC8C SLC4A7 ATP8A1 CLCN3 NALCN ANO6 DERL3 DERL2 LRRC8A LRRC8B ATP10D	9.74e-07	736	42	12	M27287
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	LRRC8E LRRC8C SLC4A7 ATP8A1 NALCN ANO6 DERL3 DERL2 LRRC8A LRRC8B ATP10D	3.35e-06	681	42	11	MM14985
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	ATP8A1 CLCN3 NALCN ANO6 ATP10D	2.01e-04	183	42	5	M997
Pubmed	Renal Deletion of LRRC8/VRAC Channels Induces Proximal Tubulopathy.	LRRC8E LRRC8C LRRC8A LRRC8B	1.89e-11	5	50	4	35777784
Pubmed	LRRC8 involved in B cell development belongs to a novel family of leucine-rich repeat proteins.	LRRC8E LRRC8C LRRC8A LRRC8B	1.89e-11	5	50	4	15094057
Pubmed	Identification of LRRC8 heteromers as an essential component of the volume-regulated anion channel VRAC.	LRRC8E LRRC8C LRRC8A LRRC8B	1.89e-11	5	50	4	24790029
Pubmed	Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity.	LRRC8E LRRC8C LRRC8A LRRC8B	1.85e-09	12	50	4	32277911
Pubmed	LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength.	LRRC8E LRRC8C LRRC8A	1.12e-08	4	50	3	26824658
Pubmed	Selective transport of neurotransmitters and modulators by distinct volume-regulated LRRC8 anion channels.	LRRC8E LRRC8A LRRC8B	1.12e-08	4	50	3	28193731
Pubmed	LRRC8A:C/E Heteromeric Channels Are Ubiquitous Transporters of cGAMP.	LRRC8E LRRC8C LRRC8A	1.12e-08	4	50	3	33171122
Pubmed	Phosphorylation-dependent Regulation of Connecdenn/DENND1 Guanine Nucleotide Exchange Factors.	DENND1B DENND1A	2.03e-06	2	50	2	26055712
Pubmed	LRRC8 family proteins within lysosomes regulate cellular osmoregulation and enhance cell survival to multiple physiological stresses.	LRRC8E LRRC8A	2.03e-06	2	50	2	33139539
Pubmed	Structure of a volume-regulated anion channel of the LRRC8 family.	LRRC8C LRRC8A	2.03e-06	2	50	2	29769723
Pubmed	Structure of a volume-regulated heteromeric LRRC8A/C channel.	LRRC8C LRRC8A	2.03e-06	2	50	2	36522427
Pubmed	The connecdenn family, Rab35 guanine nucleotide exchange factors interfacing with the clathrin machinery.	DENND1B DENND1A	6.07e-06	3	50	2	20154091
Pubmed	Protein phosphatase 2A holoenzyme assembly: identification of contacts between B-family regulatory and scaffolding A subunits.	PPP2R5A PPP2R5C	1.21e-05	4	50	2	11929880
Pubmed	Derlin-3 Is Required for Changes in ERAD Complex Formation under ER Stress.	DERL3 DERL2	1.21e-05	4	50	2	32858914
Pubmed	Complex formation of JAK2 with PP2A, P13K, and Yes in response to the hematopoietic cytokine interleukin-11.	PPP2R5A PIK3R1	1.21e-05	4	50	2	8702385
Pubmed	A membrane protein required for dislocation of misfolded proteins from the ER.	DERL3 DERL2	1.21e-05	4	50	2	15215855
Pubmed	Genomic organisation, chromosomal localisation tissue distribution and developmental regulation of the PR61/B' regulatory subunits of protein phosphatase 2A in mice.	PPP2R5A PPP2R5C	2.02e-05	5	50	2	15095873
Pubmed	The variable subunit associated with protein phosphatase 2A0 defines a novel multimember family of regulatory subunits.	PPP2R5A PPP2R5C	2.02e-05	5	50	2	8694763
Pubmed	Derlin-dependent accumulation of integral membrane proteins at cell surfaces.	DERL3 DERL2	2.02e-05	5	50	2	19509052
Pubmed	Assignment of human protein phosphatase 2A regulatory subunit genes b56alpha, b56beta, b56gamma, b56delta, and b56epsilon (PPP2R5A-PPP2R5E), highly expressed in muscle and brain, to chromosome regions 1q41, 11q12, 3p21, 6p21.1, and 7p11.2 --> p12.	PPP2R5A PPP2R5C	2.02e-05	5	50	2	8812429
Pubmed	Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation.	DERL3 DERL2	2.02e-05	5	50	2	16449189
Pubmed	Characterization of mouse and human nude genes.	FOXN2 FOXN3	2.02e-05	5	50	2	9321431
Pubmed	An Arf/Rab cascade controls the growth and invasiveness of glioblastoma.	DENND1B DENND1A	3.03e-05	6	50	2	33443570
Pubmed	Defining the membrane proteome of NK cells.	LRRC8C ATP8A1 CLCN3 NOP56 ANO6 PIK3R1 DERL2 LRRC8A ST3GAL1	3.82e-05	1168	50	9	19946888
Pubmed	The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm.	PPP2R5A PPP2R5C	4.23e-05	7	50	2	8703017
Pubmed	Identification of a new family of protein phosphatase 2A regulatory subunits.	PPP2R5A PPP2R5C	4.23e-05	7	50	2	7592815
Pubmed	A specific PP2A regulatory subunit, B56gamma, mediates DNA damage-induced dephosphorylation of p53 at Thr55.	PPP2R5A PPP2R5C	5.64e-05	8	50	2	17245430
Pubmed	Pre-emptive Quality Control Protects the ER from Protein Overload via the Proximity of ERAD Components and SRP.	DERL3 DERL2	5.64e-05	8	50	2	26565908
Pubmed	Molecular mechanism of ER stress-induced pre-emptive quality control involving association of the translocon, Derlin-1, and HRD1.	DERL3 DERL2	5.64e-05	8	50	2	29743537
Pubmed	The transmembrane segment of a tail-anchored protein determines its degradative fate through dislocation from the endoplasmic reticulum.	DERL3 DERL2	7.25e-05	9	50	2	20435896
Pubmed	Gp78 cooperates with RMA1 in endoplasmic reticulum-associated degradation of CFTRDeltaF508.	DERL3 DERL2	7.25e-05	9	50	2	18216283
Pubmed	De Novo Mutations Affecting the Catalytic Cα Subunit of PP2A, PPP2CA, Cause Syndromic Intellectual Disability Resembling Other PP2A-Related Neurodevelopmental Disorders.	PPP2R5A PPP2R5C	7.25e-05	9	50	2	30595372
Pubmed	Direct binding between BubR1 and B56-PP2A phosphatase complexes regulate mitotic progression.	PPP2R5A PPP2R5C	7.25e-05	9	50	2	23345399
Pubmed	The type 4 subfamily of P-type ATPases, putative aminophospholipid translocases with a role in human disease.	ATP8A1 ATP10D	9.05e-05	10	50	2	15919184
Pubmed	The murine fork head gene Foxn2 is expressed in craniofacial, limb, CNS and somitic tissues during embryogenesis.	FOXN2 FOXN3	9.05e-05	10	50	2	12351180
Pubmed	Regulation of Chk2 phosphorylation by interaction with protein phosphatase 2A via its B' regulatory subunit.	PPP2R5A PPP2R5C	1.32e-04	12	50	2	15380617
Pubmed	ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner.	ATP8A1 ATP10D	1.32e-04	12	50	2	21914794
Pubmed	Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I.	PPP2R5A PPP2R5C	1.32e-04	12	50	2	16541024
Pubmed	PP2A1 binding, cell transducing and apoptotic properties of Vpr(77-92): a new functional domain of HIV-1 Vpr proteins.	PPP2R5A PPP2R5C	1.56e-04	13	50	2	21072166
Pubmed	Direct activation of protein phosphatase-2A0 by HIV-1 encoded protein complex NCp7:vpr.	PPP2R5A PPP2R5C	1.82e-04	14	50	2	9013886
Pubmed	Increasing the ratio of PP2A core enzyme to holoenzyme inhibits Tat-stimulated HIV-1 transcription and virus production.	PPP2R5A PPP2R5C	1.82e-04	14	50	2	9400615
Pubmed	Dephosphorylation of CDK9 by protein phosphatase 2A and protein phosphatase-1 in Tat-activated HIV-1 transcription.	PPP2R5A PPP2R5C	1.82e-04	14	50	2	16048649
Pubmed	Aurora B and Cdk1 mediate Wapl activation and release of acetylated cohesin from chromosomes by phosphorylating Sororin.	PPP2R5A PPP2R5C	2.10e-04	15	50	2	23901111
Pubmed	Tlx1/3 and Ptf1a control the expression of distinct sets of transmitter and peptide receptor genes in the developing dorsal spinal cord.	GABRR1 GABRQ TACR2	2.20e-04	81	50	3	22723691
Pubmed	Regulation of HIV-1 transcription by protein phosphatase 1.	PPP2R5A PPP2R5C	2.72e-04	17	50	2	17266553
Pubmed	[Action of protein phosphatase-1 on Tat-dependent HIV-1 transcription and its related inhibitors].	PPP2R5A PPP2R5C	2.72e-04	17	50	2	21351466
Pubmed	Molecular mechanisms involved in HIV-1-Tat mediated inhibition of telomerase activity in human CD4(+) T lymphocytes.	PPP2R5A PPP2R5C	3.05e-04	18	50	2	23287597
Pubmed	Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype.	GABRR1 GABRQ	3.05e-04	18	50	2	19078961
Pubmed	Shugoshin collaborates with protein phosphatase 2A to protect cohesin.	PPP2R5A PPP2R5C	3.41e-04	19	50	2	16541025
Pubmed	Identification of ERAD components essential for dislocation of the null Hong Kong variant of α-1-antitrypsin (NHK).	DERL3 DERL2	3.41e-04	19	50	2	25660456
Pubmed	ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.	LRRC8E LRRC8C SLC4A7 ATP8A1 NOP56 ANO6 DERL2	4.03e-04	952	50	7	38569033
Pubmed	HIV-1 Vpr induces cell cycle G2 arrest in fission yeast (Schizosaccharomyces pombe) through a pathway involving regulatory and catalytic subunits of PP2A and acting on both Wee1 and Cdc25.	PPP2R5A PPP2R5C	6.44e-04	26	50	2	11531413
Pubmed	Biology, structure and mechanism of P-type ATPases.	ATP8A1 ATP10D	8.02e-04	29	50	2	15071553
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	PPP2R5C SLC4A7 SLC7A13 NOP56 PIK3R1 UNC5C FAM91A1	8.69e-04	1084	50	7	11544199
Pubmed	Cell Surface Proteomic Map of HIV Infection Reveals Antagonism of Amino Acid Metabolism by Vpu and Nef.	LRRC8C SLC4A7 LRRC8B	9.19e-04	132	50	3	26439863
Pubmed	The tumor suppressor PP2A Abeta regulates the RalA GTPase.	PPP2R5A PPP2R5C	9.77e-04	32	50	2	17540176
Pubmed	A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population.	DENND1A DNAH9	9.77e-04	32	50	2	23049088
Pubmed	Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.	DENND1B DENND1A	1.31e-03	37	50	2	20937701
Pubmed	Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.	PPP2R5A PPP2R5C NOP56 INTS11 HACD1	1.37e-03	573	50	5	28330616
Interaction	LRRC8B interactions	LRRC8E LRRC8C ANO6 LRRC8A LRRC8B	1.40e-08	33	48	5	int:LRRC8B
Interaction	LGALS8 interactions	LRRC8E LRRC8C SLC4A7 CLCN3 ANO6 LRRC8A SORL1	1.73e-07	174	48	7	int:LGALS8
Interaction	TTYH1 interactions	LRRC8E LRRC8C SLC4A7 ATP8A1 ANO6 TMEM161B LRRC8A LRRC8B	4.94e-07	300	48	8	int:TTYH1
Interaction	OR10H2 interactions	LRRC8E LRRC8C CLCN3 ANO6 LRRC8A	7.68e-07	72	48	5	int:OR10H2
Interaction	LGALS9B interactions	SLC4A7 CLCN3 ANO6 LRRC8A	3.93e-06	45	48	4	int:LGALS9B
Interaction	HCST interactions	LRRC8E LRRC8C PIK3R1 TMEM161B LRRC8A FAM91A1	8.85e-06	205	48	6	int:HCST
Interaction	POPDC2 interactions	LRRC8C ANO6 LRRC8A	2.17e-05	23	48	3	int:POPDC2
Interaction	NPEPPS interactions	LRRC8E LRRC8C PIK3R1 LRRC8A LRRC8B	6.23e-05	177	48	5	int:NPEPPS
Cytoband	1p22.2	LRRC8C LRRC8B	4.32e-04	28	50	2	1p22.2
GeneFamily	Volume regulated anion channel subunits	LRRC8E LRRC8C LRRC8A LRRC8B	9.23e-11	5	39	4	1158
GeneFamily	Rhomboid family	DERL3 DERL2	4.06e-04	14	39	2	926
GeneFamily	WD repeat domain containing\|Protein phosphatase 2 regulatory subunits	PPP2R5A PPP2R5C	4.68e-04	15	39	2	696
GeneFamily	ATPase phospholipid transporting	ATP8A1 ATP10D	4.68e-04	15	39	2	1210
GeneFamily	Gamma-aminobutyric acid type A receptor subunits	GABRR1 GABRQ	7.58e-04	19	39	2	563
GeneFamily	Guanylate cyclase receptors\|DENN/MADD domain containing	DENND1B DENND1A	1.32e-03	25	39	2	504
GeneFamily	Forkhead boxes	FOXN2 FOXN3	3.87e-03	43	39	2	508
CoexpressionAtlas	dev lower uro neuro_e15.5_PelvicGanglion_Sox10_top-relative-expression-ranked_1000	LRRC8C CACNA1E ATP8A1 NOP56 NALCN UNC5C GPR63 CLVS1 C18orf32	2.81e-05	734	47	9	gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_1000
ToppCell	5'-Adult-LymphNode-Hematopoietic-T_cells-CX3CR1+_CD8_Tmem\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPP2R5C PIK3R1 ST3GAL1 FER1L5	4.43e-05	175	50	4	dddeced0cfcf71d03bcf349983908b3bfb0ab51d
ToppCell	Control-T_cells\|Control / group, cell type (main and fine annotations)	LRRC8C PPP2R5C SLC4A7 SORL1	5.73e-05	187	50	4	f4e8e0eba58da89b56587667555a5d4754e108c7
ToppCell	COPD-Lymphoid-T_Cytotoxic\|Lymphoid / Disease state, Lineage and Cell class	PPP2R5C ATP8A1 PIK3R1 ST3GAL1	6.10e-05	190	50	4	10bece40d980d37a01dae8ce887655bf9f93040c
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD8\|bone_marrow / Manually curated celltypes from each tissue	PPP2R5C SLC4A7 ATP8A1 PIK3R1	6.10e-05	190	50	4	be281c7c717c11ef3c5cbccd22628acf1bd9727f
ToppCell	IPF-Lymphoid-T\|IPF / Disease state, Lineage and Cell class	LRRC8C PPP2R5C SLC4A7 ATP8A1	6.10e-05	190	50	4	d57df208aaf7a5554899bb9107c80b443fd0cf93
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Inhibitory_Neuron.Gad1Gad2.Vip_(ventral_GP_(vGP))\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	GABRR1 NPC1L1 GPR63	6.15e-05	68	50	3	ad6c363d7fb3c436e894db30a544748c5df75a45
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Inhibitory_Neuron.Gad1Gad2.Vip_(ventral_GP_(vGP))--\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	GABRR1 NPC1L1 GPR63	6.15e-05	68	50	3	82d928f5eefa065d26096a84b0d78f131dcc8c73
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Inhibitory_Neuron.Gad1Gad2.Vip_(ventral_GP_(vGP))-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	GABRR1 NPC1L1 GPR63	6.15e-05	68	50	3	d97199a8c6afa79bff1600f00c2dbf6286df24a2
ToppCell	COVID-19-T_cells-CD4+_T_cells\|COVID-19 / group, cell type (main and fine annotations)	LRRC8C PPP2R5C ATP8A1 SORL1	6.22e-05	191	50	4	0646cca78e24aeb6baa9934d3c439b797c567997
ToppCell	COPD-Lymphoid-T\|World / Disease state, Lineage and Cell class	LRRC8C PPP2R5C SLC4A7 ATP8A1	6.35e-05	192	50	4	eb4909574fb5fc91399463523e2737095773200a
ToppCell	COPD-Lymphoid-T_Cytotoxic\|COPD / Disease state, Lineage and Cell class	LRRC8C PPP2R5C ATP8A1 PIK3R1	6.48e-05	193	50	4	58e94fe2e89cdafc6974938f97a4c162061a437d
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-T_cells-TRGV2_gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPP2R5C ATP8A1 PIK3R1 ST3GAL1	6.48e-05	193	50	4	544de0988510cc57744710d7cafe07aa27a0b99d
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PPP2R5C SLC4A7 ATP8A1 PIK3R1	6.48e-05	193	50	4	a594f89a18273797506287d9e22f72abe53e4920
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	PPP2R5C SLC4A7 ATP8A1 SORL1	6.48e-05	193	50	4	00349d176fb6a46cbcc99c41d975651b6e9aaad4
ToppCell	IPF-Lymphoid-T_Cytotoxic\|Lymphoid / Disease state, Lineage and Cell class	LRRC8C PPP2R5C ATP8A1 PIK3R1	6.48e-05	193	50	4	3c8a022dbd4f8d25b14fd137ce64c2713a7dbe41
ToppCell	Smart-seq2-bone_marrow_(Smart-seq2)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell\|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	LRRC8C PPP2R5C ATP8A1 PIK3R1	6.61e-05	194	50	4	bf2480acec5612cd8a3c33d3e7a98176dc6c9091
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-T_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	LRRC8C PPP2R5C ATP8A1 PIK3R1	6.88e-05	196	50	4	4a880a5d2c7047c050c7d6dd62186f35dc5c01f7
ToppCell	Bronchial_Brush-Epithelial-Club\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	ST3GAL1 FOXN3 REEP3 SORL1	7.15e-05	198	50	4	61292a2b5aacb6080a679a31b70a211bdec59a3b
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-T_lymphocytic-naive_thymus-derived_CD8-positive,_alpha-beta_T_cell\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	LRRC8C PPP2R5C SLC4A7 PIK3R1	7.29e-05	199	50	4	db05c16d80f5a74bfa048a5c92917d312d26f769
ToppCell	Bronchial_Brush-Epithelial-Club\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	ST3GAL1 FOXN3 REEP3 SORL1	7.29e-05	199	50	4	53b87edccc89a3e8a6c5166472f9ef24fcba416c
ToppCell	PBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_0\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CACNA1E CMTM2 UNC5C	4.00e-04	128	50	3	9b3c57d559a5ed8d590dd89b64a57a3227d8c684
ToppCell	PBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_0\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CACNA1E CMTM2 UNC5C	4.00e-04	128	50	3	58639cfdc70ff6764adcc5c1ce9eba9d033b8209
ToppCell	3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	PPP2R5C SLC4A7 DENND1B	4.67e-04	135	50	3	ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	LRRC8C SLC4A7 ATP8A1	5.19e-04	140	50	3	7b359bfbd404ab06d799048252f4985d85852048
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4\|356C / Donor, Lineage, Cell class and subclass (all cells)	PPP2R5C PIK3R1 NPC1L1	5.52e-04	143	50	3	e8fc6540a48086f58bc3f42dabe392ef46715b9e
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	UNC5C DNAH9 SORL1	5.64e-04	144	50	3	08005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	UNC5C GPR63 ST3GAL1	6.10e-04	148	50	3	f85dc34f6a4a15ecffa4fbd5644dea12ce30089b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	UNC5C GPR63 ST3GAL1	6.10e-04	148	50	3	4b1fdf90c585f89cee1cf521db4e3fafc9d74d9a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	UNC5C GPR63 ST3GAL1	6.10e-04	148	50	3	55826b7e9f79ab78a93abd4fc662bc37aa121471
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FOXN2 UNC5C AWAT1	6.35e-04	150	50	3	8645b9c7f9511ed6cc9afe04440c2873a3094150
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|343B / Donor, Lineage, Cell class and subclass (all cells)	POP4 SLC4A7 SORL1	6.47e-04	151	50	3	78475027bba9e3026e42493fec8ea630972353bb
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	PPP2R5C ATP8A1 SORL1	7.24e-04	157	50	3	170197b76620df31495f1247f365da382b2d8045
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM\|Lung / Manually curated celltypes from each tissue	PPP2R5C ATP8A1 PIK3R1	7.24e-04	157	50	3	af6eb2214340847bbab7cb209ea27cdc83b62a27
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PPP2R5C PIK3R1 NPC1L1	7.24e-04	157	50	3	f2bc60ec0305b056d79f1b7fd6b5e3730d606916
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	PPP2R5C ATP8A1 SORL1	7.24e-04	157	50	3	c21520301cc0d5d4b1cc4b8ec735f9adb698e768
ToppCell	facs-GAT-Fat-24m\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1E DERL3 GABRQ	7.24e-04	157	50	3	c4a0b6c95d353691fd2846002ce4bc7c2b0edd1c
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	PPP2R5C ATP8A1 SORL1	7.38e-04	158	50	3	7274f020c0ecf216da4b6689c62bc5f49c29b6f3
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-24m-Lymphocytic-B_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1E DERL3 ZDHHC11	7.65e-04	160	50	3	6bafbe2b4b98bc088406a516d079093f89d9c344
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	CLCN3 DDX60L KDM8	7.65e-04	160	50	3	636127753e3a22831f39d4c8170df40901e4329d
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	CLCN3 DDX60L KDM8	7.65e-04	160	50	3	cb8d0dc1a6c69c7a85c5fdd8f0f6cca1b73dfc63
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	PPP2R5A NALCN LRRC8A	7.79e-04	161	50	3	347edb0de10850b7d16c40945751033289289c9b
ToppCell	Influenza_Severe-Neutrophil\|Influenza_Severe / Disease group and Cell class	CACNA1E CMTM2 SORL1	7.79e-04	161	50	3	98c95b1b85d5427415af2ca8fb14849e97f6e8b5
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXN2 ATP8A1 ANO6	8.07e-04	163	50	3	8dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	SLC7A13 PIK3R1 SORL1	8.07e-04	163	50	3	9195051d6bcdd450ed745a099828a0d76d9d3f0b
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXN2 ATP8A1 ANO6	8.07e-04	163	50	3	fd243ca223079033be480a24817a399f281fa4d4
ToppCell	severe_influenza-CD4+_CTL\|severe_influenza / disease group, cell group and cell class (v2)	PPP2R5C SLC4A7 PIK3R1	8.81e-04	168	50	3	50697fda702a09d9a621e9f79c2b52d53792dd2a
ToppCell	390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|390C / Donor, Lineage, Cell class and subclass (all cells)	SLC4A7 ATP8A1 CMTM2	8.96e-04	169	50	3	cfc9ff103d13a2d5eacc457e800f53fdd29f7738
ToppCell	Influenza_Severe-Neutrophil\|World / Disease group and Cell class	CACNA1E CMTM2 SORL1	8.96e-04	169	50	3	6e8e2580e19c96bcf7fa6a6d8c183df65f428396
ToppCell	saliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NPFFR2 SLC4A7 ATP8A1	9.12e-04	170	50	3	32917888c3f1d54302675c1d4de1fd3b7c79af5f
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4/8-lo\|Lung / Manually curated celltypes from each tissue	PPP2R5C ATP8A1 PIK3R1	9.27e-04	171	50	3	dfd4a15ab68ef5a9a1954b1b1540ae04017885a6
ToppCell	facs\|World / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP2R5C LRRC8A SORL1	9.27e-04	171	50	3	c9990bc041a632b2f7bbebbfe737772c423d7027
ToppCell	normal-na-Lymphocytic_T-T4_em-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	PPP2R5C SLC4A7 PIK3R1	9.27e-04	171	50	3	61318a7aaf3bd8bdd28f8a8614ab4fdf2964b3a3
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	NPFFR2 CMTM2 SORL1	9.27e-04	171	50	3	2b7c5a557c4bc5c573211c4d618bdd6766a24916
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	NPFFR2 CMTM2 SORL1	9.27e-04	171	50	3	dcb15bc54aeea06ef8f07f1134f3ff1e21ac0e4f
ToppCell	BAL-Severe-Myeloid-Neutrophil-Neutrophil-Neu_3\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CACNA1E CMTM2 DDX60L	9.59e-04	173	50	3	1edef5aeab626cbf2c09468e77b02cfa2d21ba03
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ATP8A1 PIK3R1 FER1L5	9.59e-04	173	50	3	0c74bdb40e635d906fd180412c23bf7fed61621e
ToppCell	BAL-Severe-Myeloid-Neutrophil-Neutrophil\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CACNA1E CMTM2 DDX60L	9.59e-04	173	50	3	c37dba3804df7c3151e18e6ae4e0b6e7a92bae97
ToppCell	ILEUM-inflamed-(1)_T_(gd)\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PPP2R5C ATP8A1 PIK3R1	9.59e-04	173	50	3	85c3e227c81c6ab70148639381389fba3ac5e088
ToppCell	BAL-Severe-Myeloid-Neutrophil\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CACNA1E CMTM2 DDX60L	9.59e-04	173	50	3	5b76d9cc56bbb29017e64a2d0a3c76c0be003d96
ToppCell	BAL-Severe-Myeloid-Neutrophil-Neutrophil-Neu_3\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CACNA1E CMTM2 DDX60L	9.59e-04	173	50	3	bf685025961e79b379f2c35464b6c8ce3e31ace0
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_28\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRRC8C ATP8A1 ZDHHC11	9.59e-04	173	50	3	66488d01e03264fb193285470901c9c4182fbae8
ToppCell	BAL-Severe-Myeloid-Neutrophil\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CACNA1E CMTM2 DDX60L	9.59e-04	173	50	3	a6e73a40b0d5356564a594053e772f9d061a5919
ToppCell	severe_influenza-Neutrophil\|severe_influenza / disease group, cell group and cell class (v2)	CACNA1E CMTM2 SORL1	9.59e-04	173	50	3	615e266419b9f06e964eff73cb466f05451ba0dd
ToppCell	BAL-Severe-Myeloid-Neutrophil-Neutrophil\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CACNA1E CMTM2 DDX60L	9.59e-04	173	50	3	a8b5370f4c893a20c58e97659f3ac168699693f8
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NPFFR2 CACNA1E GPR63	9.75e-04	174	50	3	bc978a2148a0261a4f9d1ca5479b707e224566be
ToppCell	Healthy-Plasmablast\|World / disease group, cell group and cell class	ALG14 DERL3 CLVS1	9.75e-04	174	50	3	6becb456d8f44a1224c6d42be78d4c8cdb51f199
ToppCell	severe_influenza-Neutrophil\|World / disease group, cell group and cell class (v2)	CACNA1E CMTM2 SORL1	9.75e-04	174	50	3	f9f07436b7d3f190800cd85d229f007032f391e1
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PPP2R5A PPP2R5C DENND1A	9.91e-04	175	50	3	a3f8c54c77bce9b035a4835945ab341909be4946
ToppCell	COPD-Lymphoid-ILC_A\|World / Disease state, Lineage and Cell class	PPP2R5C ATP8A1 PIK3R1	9.91e-04	175	50	3	e773e330de36f8a0aa9398a176ed7edb5599c582
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PPP2R5C PIK3R1 ST3GAL1	1.01e-03	176	50	3	ce85a13e10cf37f5cf38ca8b0bac6701b6d00ffd
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DENND1B UNC5C SORL1	1.02e-03	177	50	3	c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCell	Severe-Myeloid-Neutrophil\|Severe / Condition, Lineage, Cell class and cell subclass	CACNA1E CMTM2 DDX60L	1.04e-03	178	50	3	454313efe59d71e7327b9758efabf2d893e4a8fd
ToppCell	Severe-Myeloid-Neutrophil-\|Severe / Condition, Lineage, Cell class and cell subclass	CACNA1E CMTM2 DDX60L	1.04e-03	178	50	3	8618ae891d62bf70fe860ff7bb2d31868961aa13
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	PPP2R5C ATP8A1 SORL1	1.04e-03	178	50	3	73936c2e7e8855b4ab65cad425686513dba331a3
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-T4_reg-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	PPP2R5C PIK3R1 HACD1	1.04e-03	178	50	3	90dedb3cef9b01907b9f8eec64218d6d2072be1f
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-T4_reg\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	PPP2R5C PIK3R1 HACD1	1.04e-03	178	50	3	d6312286bf6cc5b107ccd7adb583d9667d4e1d21
ToppCell	ILEUM-non-inflamed-(1)_T_(gd)\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PPP2R5C ATP8A1 PIK3R1	1.07e-03	180	50	3	44c37644973c4fc555dc966f8cfe1f4f81fef300
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	PPP2R5C PIK3R1 SORL1	1.07e-03	180	50	3	f3d35b2ea78afef37a84232adf5e6e26712b618d
ToppCell	COVID-19-kidney-NK\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PPP2R5C ATP8A1 SORL1	1.09e-03	181	50	3	8906ee8a7a1616dfe8c3b5c73988416641213629
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_4\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	ANO6 LRRC8B FOXN3	1.13e-03	183	50	3	3cbe0175d05fd39bc430de1ef471ff2c5b56460e
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM\|bone_marrow / Manually curated celltypes from each tissue	PPP2R5C ATP8A1 PIK3R1	1.13e-03	183	50	3	37db007cc65005bffc18a5fda7f454a57c9fb0a9
ToppCell	CF-Myeloid-Neutrophil\|CF / Disease state, Lineage and Cell class	CMTM2 DDX60L SORL1	1.13e-03	183	50	3	da43827952e6fdee2ce94648c316182f272b321c
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	PPP2R5C RBL1 SORL1	1.13e-03	183	50	3	f2ef110bf29b1a8276ef216238363e542db262c1
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4/8-lo\|bone_marrow / Manually curated celltypes from each tissue	PPP2R5C ATP8A1 PIK3R1	1.13e-03	183	50	3	2fb78622adc170dd3301e251418337523de50faf
ToppCell	ILEUM-inflamed-(1)_T_cell-(1)_CD8_Trm\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PPP2R5C SLC4A7 PIK3R1	1.15e-03	184	50	3	cef3ee2a4a0af961aa3b4c92150d423e841ae8c1
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	DENND1B DENND1A ATP10D	1.16e-03	185	50	3	e06a784a297f357f3f8e761c24fa70722048ab42
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PPP2R5C ATP8A1 SORL1	1.18e-03	186	50	3	9d576dce2c5deefef1adda16c6da7055c8d57f8f
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	PPP2R5C PIK3R1 SORL1	1.18e-03	186	50	3	c793a3d5709ad504c12fc3b2337746d90236d3ca
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PPP2R5C ATP8A1 SORL1	1.18e-03	186	50	3	bd3bd022b575d9b0ef90d50a5cb874085a827b77
ToppCell	3'-Adult-SmallIntestine-Epithelial-mature_enterocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANO6 NPC1L1 FOXN3	1.18e-03	186	50	3	bdd9d3a432aab46e733469b362f0064d35c1ac49
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PPP2R5C ATP8A1 SORL1	1.18e-03	186	50	3	924cc357b4c4ce8e9b05773bdab544f0b65474cc
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-effector_CD4-positive,_alpha-beta_T_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PPP2R5C PIK3R1 SORL1	1.20e-03	187	50	3	e61c1755531469dd3850c9740474b5ad4e0499c1
ToppCell	3'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANO6 NPC1L1 FOXN3	1.20e-03	187	50	3	9042bd0f57213a51503d9df2e4dce3209b7772d3
ToppCell	ILEUM-inflamed-(1)_CD8_Trm\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PPP2R5C SLC4A7 PIK3R1	1.20e-03	187	50	3	a77d7ae44f47410bd92fb3aa0f44dce891752b63
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	PPP2R5C PIK3R1 SORL1	1.20e-03	187	50	3	e1d6c1194476cf26969e405b0951796fed519f44
ToppCell	Fetal_29-31_weeks-Immune-natural_killer_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ATP8A1 PIK3R1 SORL1	1.22e-03	188	50	3	6686dbba990066568aa7573e70a7db8b4758f457
ToppCell	COPD-Lymphoid-NK\|COPD / Disease state, Lineage and Cell class	PPP2R5C ATP8A1 SORL1	1.22e-03	188	50	3	c9a227c8e71b69929d43e9afb8306a95c8163778
ToppCell	PBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CACNA1E CMTM2 SORL1	1.22e-03	188	50	3	aa46073e2940dc1d2020b2e259bf0fc06cb990ee
ToppCell	PBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CACNA1E CMTM2 SORL1	1.22e-03	188	50	3	04814b78da936a51a497e23060d19ca0d619e250
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-T4_reg\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	PPP2R5C PIK3R1 HACD1	1.22e-03	188	50	3	e5c480b9a030536578f1cc91fb61738f752525b3
Disease	Agammaglobulinemia, non-Bruton type	PIK3R1 LRRC8A	7.21e-05	8	48	2	C1832241
Disease	Agammaglobulinemia	PIK3R1 LRRC8A	1.69e-04	12	48	2	C0001768
Disease	unipolar depression	NPFFR2 CACNA1E DENND1B NALCN TMEM161B UNC5C DENND1A CLVS1	6.70e-04	1206	48	8	EFO_0003761
Disease	macular telangiectasia type 2	PPP2R5A REEP3	8.21e-04	26	48	2	EFO_1002009
Disease	verbal-numerical reasoning measurement	CACNA1E PIK3R1 FOXN3	1.28e-03	131	48	3	EFO_0008394
Disease	personality trait	ST3GAL1 DENND1A	1.85e-03	39	48	2	EFO_0004365
Disease	glucagon measurement	CACNA1E PIK3R1 KDM8	2.03e-03	154	48	3	EFO_0008463
Disease	unipolar depression, bipolar disorder	CACNA1E DENND1B DENND1A	2.11e-03	156	48	3	EFO_0003761, MONDO_0004985
Disease	complement factor H-related protein 5 measurement	DENND1B SORL1	2.14e-03	42	48	2	EFO_0008098
Disease	developmental disorder of mental health (implicated_via_orthology)	GABRR1 GABRQ	2.90e-03	49	48	2	DOID:0060037 (implicated_via_orthology)
Disease	macula measurement	TMEM161B DENND1A SORL1	3.62e-03	189	48	3	EFO_0008375
Disease	feeling emotionally hurt measurement	CACNA1E DENND1B	3.77e-03	56	48	2	EFO_0009599
Disease	polycystic ovary syndrome	UNC5C DENND1A	4.32e-03	60	48	2	EFO_0000660
Disease	anxiety	DENND1B TMEM161B DENND1A	5.73e-03	223	48	3	EFO_0005230

Protein segments in the cluster

Peptide	Gene	Start	Entry
PQWLTHLLYYAEFLF	CACNA1E	501	Q15878
WPHLQLVYEFFLRFL	PPP2R5C	131	Q13362
KILFHLSDYFIVQWP	ALG14	186	Q96F25
LYFNPHLVFRKFQVW	DERL3	41	Q96Q80
HSVILFWFPLKALQY	ATP8A1	951	Q9Y2Q0
YLPHTFWITLLDAFY	ATP10D	1191	Q9P241
VLLWIYKKFLEPYIY	C18orf32	11	Q8TCD1
IINIYIYPFAHWLAF	NPFFR2	411	Q9Y5X5
NRLHWFAKYFPYLVL	LRRC8A	116	Q8IWT6
YYWHVIAAKLAFIIV	ANO6	826	Q4KMQ2
EWYGYHFPELVKIIN	NOP56	191	O00567
LTEKANHYYKLFIPW	INTS11	271	Q5TA45
PLAFGLFNIVYWVYH	GABRQ	616	Q9UN88
IPEVSSVWFKLYIYH	FAM91A1	526	Q658Y4
ILFIPVKYWHYVRAL	KDM8	391	Q8N371
WKLFLEQHYPYFLIV	DDX60L	131	Q5H9U9
LHWYAKYFPYLVVIH	LRRC8E	111	Q6NSJ5
YWLTLQYLLKHFFKL	PIK3R1	236	P27986
WFAKFFPYLVLLHTL	LRRC8B	116	Q6P9F7
YEEQHLYFYKVWLPL	FADS2B	296	A8MWK0
FFQKAYAPFLLHWIT	NPC1L1	831	Q9UHC9
IIFPAAYILFNLIYW	GABRR1	461	P24046
PHIKPEWYFLFAYTI	MT-CYB	266	P00156
PVKDIYNWILEHFPY	FOXN3	136	O00409
YTFSLLDHLPYFIKW	HACD1	186	B0YJ81
LDHLPYFIKWARYNF	HACD1	191	B0YJ81
SYLAIFWILQPLFVY	AWAT1	21	Q58HT5
SYLPWFEVFYKLLNI	DENND1A	101	Q8TEH3
KEIYSWILDHFPYFA	FOXN2	136	P32314
LNPLIYYWRIKKFHD	GPR63	366	Q9BZJ6
PKEIYEHYFVFAAIW	DNAH9	2366	Q9NYC9
LYFNPELIFKHFQIW	DERL2	41	Q9GZP9
LPWFEVYYKLLNTLA	DENND1B	101	Q6P3S1
VLTFAICWLPYHLYF	TACR2	256	P21452
PHPYAIAVFKNEIYW	SORL1	961	Q92673
LIYLRYVPLWKVHIF	SLC4A7	1071	Q9Y6M7
LALHYFPEYQWLVDF	TMEM161B	96	Q8NDZ6
PKWPYFIQYKHFSLF	FER1L5	1861	A0AVI2
WIIEVLNLQPFYFYK	RBL1	521	P28749
YSLFLPLHELWKQYI	POP4	96	O95707
IYHPAFIKYVFDNWL	ST3GAL1	246	Q11201
YELKIAFVIWLLSPY	REEP3	66	Q6NUK4
WPHIQLVYEFFLRFL	PPP2R5A	156	Q15172
LYSFAIHRYIPFILW	CMTM2	131	Q8TAZ6
YHTPWYLFELFPFIL	CLCN3	381	P51790
PWYIHALYTLIKPFL	CLVS1	226	Q8IUQ0
LLFFPYLHQDWEVQY	YIF1B	126	Q5BJH7
YIPLIHFKIRLAWFE	SLC7A13	436	Q8TCU3
IPFLPHAWKYIAYVV	ZDHHC11	61	Q9H8X9
KLLAKYQEIPFYHVW	UNC5C	756	O95185
HWYAKYFPYLVLIHT	LRRC8C	121	Q8TDW0
WAPVVAIYFILYHLF	NALCN	571	Q8IZF0