Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH10 DNAH17 DNAH11

3.38e-0518713GO:0008569
GeneOntologyMolecularFunctiontestosterone 6-beta-hydroxylase activity

CYP3A7 CYP3A4

1.24e-045712GO:0050649
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH10 DNAH17 DNAH11

1.32e-0428713GO:0051959
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH10 DNAH17 DNAH11

3.07e-0437713GO:0045505
GeneOntologyMolecularFunctionestrogen 2-hydroxylase activity

CYP3A7 CYP3A4

3.44e-048712GO:0101021
GeneOntologyMolecularFunctionestrogen 16-alpha-hydroxylase activity

CYP3A7 CYP3A4

6.72e-0411712GO:0101020
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNAH10 MYO7A DNAH17 DNAH11

8.30e-04118714GO:0003774
GeneOntologyMolecularFunctionD1 dopamine receptor binding

PTPN11 NSF

1.10e-0314712GO:0031748
GeneOntologyMolecularFunctionretinoic acid 4-hydroxylase activity

CYP3A7 CYP3A4

1.10e-0314712GO:0008401
GeneOntologyBiologicalProcesspositive regulation of striated muscle contraction

TRPV4 CCN2 GSTO1

2.68e-0517723GO:0045989
GeneOntologyBiologicalProcessestrogen metabolic process

CYP3A7 CYP3A4 UGT2A3 UGT2B10

3.26e-0552724GO:0008210
GeneOntologyBiologicalProcessnegative regulation of cholangiocyte proliferation

LIMS1 LIMS2

3.60e-053722GO:1904055
GeneOntologyBiologicalProcesshormone metabolic process

CYP3A7 PTPN11 CYP3A4 UGT2A3 RDH10 GATA3 UGT2B10

6.25e-05286727GO:0042445
GeneOntologyBiologicalProcessintegrin-mediated signaling pathway

LIMS1 PTPN11 ILK CCN2 LIMS2

7.34e-05124725GO:0007229
GeneOntologyBiologicalProcessmicrotubule depolymerization

TRPV4 CCN2 RP1 WDR47

8.35e-0566724GO:0007019
GeneOntologyBiologicalProcessxenobiotic metabolic process

CYP3A7 CYP3A4 SLCO2B1 UGT2B10 GSTO1

1.35e-04141725GO:0006805
GeneOntologyBiologicalProcessprotein depolymerization

LIMA1 TRPV4 CCN2 RP1 WDR47

1.49e-04144725GO:0051261
DomainATPase_dyneun-rel_AAA

MDN1 DNAH10 DNAH11

1.78e-0514703IPR011704
DomainAAA_5

MDN1 DNAH10 DNAH11

1.78e-0514703PF07728
DomainPINCH

LIMS1 LIMS2

4.14e-053702IPR017351
DomainLIM

LIMA1 LIMS1 TES LIMS2

1.30e-0469704PF00412
DomainCyt_P450_E_grp-II

CYP3A7 CYP3A4

1.37e-045702IPR002402
Domain-

LIMA1 LIMS1 TES LIMS2

1.38e-04707042.10.110.10
DomainZnf_LIM

LIMA1 LIMS1 TES LIMS2

1.45e-0471704IPR001781
DomainLIM_DOMAIN_1

LIMA1 LIMS1 TES LIMS2

1.45e-0471704PS00478
DomainLIM_DOMAIN_2

LIMA1 LIMS1 TES LIMS2

1.45e-0471704PS50023
DomainLIM

LIMA1 LIMS1 TES LIMS2

1.45e-0471704SM00132
DomainCyt_P450_E_CYP3A

CYP3A7 CYP3A4

2.06e-046702IPR008072
DomainDHC_N1

DNAH10 DNAH11

3.82e-048702PF08385
DomainDynein_heavy_dom-1

DNAH10 DNAH11

3.82e-048702IPR013594
DomainDynein_heavy_chain_D4_dom

DNAH10 DNAH11

1.22e-0314702IPR024317
DomainDynein_HC_stalk

DNAH10 DNAH11

1.22e-0314702IPR024743
DomainDynein_heavy_dom-2

DNAH10 DNAH11

1.22e-0314702IPR013602
DomainDHC_N2

DNAH10 DNAH11

1.22e-0314702PF08393
DomainMT

DNAH10 DNAH11

1.22e-0314702PF12777
DomainAAA_8

DNAH10 DNAH11

1.22e-0314702PF12780
DomainDHC_fam

DNAH10 DNAH11

1.41e-0315702IPR026983
DomainDynein_heavy_dom

DNAH10 DNAH11

1.41e-0315702IPR004273
DomainDynein_heavy

DNAH10 DNAH11

1.41e-0315702PF03028
DomainAAA+_ATPase

MDN1 DNAH10 NSF DNAH11

2.10e-03144704IPR003593
DomainAAA

MDN1 DNAH10 NSF DNAH11

2.10e-03144704SM00382
DomainApc4_WD40_dom

EML5 WDR47

2.52e-0320702IPR024977
DomainANAPC4_WD40

EML5 WDR47

2.52e-0320702PF12894
DomainUDPGT

UGT2A3 UGT2B10

2.78e-0321702PF00201
DomainUDPGT

UGT2A3 UGT2B10

2.78e-0321702PS00375
DomainUDP_glucos_trans

UGT2A3 UGT2B10

2.78e-0321702IPR002213
DomainTPR_REGION

TRANK1 DNAH10 TTC21B TTC3

3.42e-03165704PS50293
DomainTPR

TRANK1 DNAH10 TTC21B TTC3

3.42e-03165704PS50005
DomainC2H2_Znf_fam

ZNF518B ZNF518A

3.62e-0324702IPR027775
Domain-

GDPD3 PLCG1

3.93e-03257023.20.20.190
DomainPLC-like_Pdiesterase_TIM-brl

GDPD3 PLCG1

3.93e-0325702IPR017946
Domain-

EFL1 TRANK1 MDN1 DNAH10 MYO7A NSF ERCC6L2 DNAH11

6.63e-037467083.40.50.300
Domain-

TRANK1 TTC21B KDM6B TTC3

7.60e-032077041.25.40.10
PathwayKEGG_RETINOL_METABOLISM

CYP3A7 CYP3A4 UGT2A3 RDH10 UGT2B10

2.18e-0664475M9488
PathwayKEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450

CYP3A7 CYP3A4 UGT2A3 UGT2B10 GSTO1

3.41e-0670475M16794
PathwayKEGG_DRUG_METABOLISM_CYTOCHROME_P450

CYP3A7 CYP3A4 UGT2A3 UGT2B10 GSTO1

3.92e-0672475M9257
PathwayREACTOME_ASPIRIN_ADME

CYP3A4 SLCO2B1 UGT2A3 UGT2B10

1.34e-0544474M45014
PathwayREACTOME_ASPIRIN_ADME

CYP3A4 SLCO2B1 UGT2A3 UGT2B10

1.46e-0545474MM15694
PathwayKEGG_DRUG_METABOLISM_OTHER_ENZYMES

CYP3A7 CYP3A4 UGT2A3 UGT2B10

2.42e-0551474M17726
PathwayREACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS

LIMS1 ILK LIMS2

2.74e-0518473MM15123
PathwayREACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS

LIMS1 ILK LIMS2

2.74e-0518473M840
PathwayKEGG_STEROID_HORMONE_BIOSYNTHESIS

CYP3A7 CYP3A4 UGT2A3 UGT2B10

3.27e-0555474M14933
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

CYP3A7 CYP3A4 ESD UGT2A3 UGT2B10 GSTO1

8.49e-05220476M10320
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH10 DNAH17 DNAH11

9.61e-0527473M47755
PathwayKEGG_LINOLEIC_ACID_METABOLISM

CYP3A7 CYP3A4 PLA2G4A

1.19e-0429473M2920
PathwayWP_PDGF_PATHWAY

PTPN11 PLA2G4A PLCG1

3.15e-0440473M39555
PathwayREACTOME_ATORVASTATIN_ADME

CYP3A4 SLCO2B1

3.86e-049472M45020
PathwayKEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT

DNAH10 DNAH17 DNAH11

3.90e-0443473M47669
PathwayREACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS

ESD UGT2A3 UGT2B10 GSTO1

4.35e-04107474MM14595
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH10 DNAH17 DNAH11

4.47e-0445473M47670
PathwayPID_ILK_PATHWAY

LIMS1 ILK LIMS2

4.47e-0445473M71
PathwayREACTOME_DRUG_ADME

CYP3A4 SLCO2B1 UGT2A3 UGT2B10

4.67e-04109474M45012
PathwayREACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS

ESD UGT2A3 UGT2B10 GSTO1

4.67e-04109474M18788
PathwayREACTOME_DRUG_ADME

CYP3A4 SLCO2B1 UGT2A3 UGT2B10

6.51e-04119474MM15692
PathwayKEGG_STARCH_AND_SUCROSE_METABOLISM

UGT2A3 UGT2B10 PYGB

6.85e-0452473M14171
PathwayREACTOME_PECAM1_INTERACTIONS

PTPN11 PLCG1

7.03e-0412472MM14835
PathwayREACTOME_PECAM1_INTERACTIONS

PTPN11 PLCG1

7.03e-0412472M11773
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

CYP3A4 ESD UGT2A3 UGT2B10 GSTO1

7.80e-04219475MM14838
PathwayPID_FCER1_PATHWAY

PTPN11 PLA2G4A PLCG1

1.04e-0360473M7
PathwayREACTOME_ATORVASTATIN_ADME

CYP3A4 SLCO2B1

1.11e-0315472MM15697
PathwayREACTOME_PLATELET_SENSITIZATION_BY_LDL

PTPN11 PLA2G4A

1.43e-0317472MM15096
PathwayREACTOME_PLATELET_SENSITIZATION_BY_LDL

PTPN11 PLA2G4A

1.43e-0317472M919
Pubmed

Characterization of PINCH-2, a new focal adhesion protein that regulates the PINCH-1-ILK interaction, cell spreading, and migration.

LIMS1 ILK LIMS2

8.87e-09373312167643
Pubmed

Consequences of loss of PINCH2 expression in mice.

LIMS1 ILK LIMS2

8.87e-09373316317048
Pubmed

A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading.

LIMS1 ILK LIMS2

3.54e-08473311331308
Pubmed

Dissecting integrin-dependent regulation of neural stem cell proliferation in the adult brain.

LIMS1 ILK LIMS2

8.84e-08573324719101
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

TRANK1 SALL2 MDN1 MAST4 KDM6B ZNF518A

8.94e-081047369205841
Pubmed

Mutations in the paxillin-binding site of integrin-linked kinase (ILK) destabilize the pseudokinase domain and cause embryonic lethality in mice.

LIMS1 ILK LIMS2

4.93e-07873323658024
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH10 DNAH17 DNAH11

3.18e-06147339373155
Pubmed

Targeted ablation of PINCH1 and PINCH2 from murine myocardium results in dilated cardiomyopathy and early postnatal lethality.

LIMS1 ILK LIMS2

3.18e-061473319652092
Pubmed

Digging Deeper into CYP3A Testosterone Metabolism: Kinetic, Regioselectivity, and Stereoselectivity Differences between CYP3A4/5 and CYP3A7.

CYP3A7 CYP3A4

4.35e-06273228986474
Pubmed

Inhibition of integrin-linked kinase via a siRNA expression plasmid attenuates connective tissue growth factor-induced human proximal tubular epithelial cells to mesenchymal transition.

ILK CCN2

4.35e-06273217951996
Pubmed

Signaling via PINCH: Functions, binding partners and implications in human diseases.

LIMS1 LIMS2

4.35e-06273227590440
Pubmed

PINCH-1 promotes tubular epithelial-to-mesenchymal transition by interacting with integrin-linked kinase.

LIMS1 ILK

4.35e-06273217656471
Pubmed

The structural basis of integrin-linked kinase-PINCH interactions.

LIMS1 ILK

4.35e-06273219074270
Pubmed

Structural basis of focal adhesion localization of LIM-only adaptor PINCH by integrin-linked kinase.

LIMS1 ILK

4.35e-06273219117955
Pubmed

Focal adhesion proteins Pinch1 and Pinch2 regulate bone homeostasis in mice.

LIMS1 LIMS2

4.35e-06273231723057
Pubmed

Differential regulation of CYP3A4 and CYP3A7 by dimethylsulfoxide in primary human hepatocytes.

CYP3A7 CYP3A4

4.35e-06273215379787
Pubmed

A2 isoform of mammalian translation factor eEF1A displays increased tyrosine phosphorylation and ability to interact with different signalling molecules.

PTPN11 PLCG1

4.35e-06273217936057
Pubmed

LIM domain proteins Pinch1/2 regulate chondrogenesis and bone mass in mice.

LIMS1 LIMS2

4.35e-06273233083097
Pubmed

Dynamics of Cytosine Methylation in the Proximal Promoters of CYP3A4 and CYP3A7 in Pediatric and Prenatal Livers.

CYP3A7 CYP3A4

4.35e-06273226772622
Pubmed

Integrin-linked kinase (ILK) and src homology 2 domain-containing phosphatase 2 (SHP2): Novel targets in EGFR-mutation positive non-small cell lung cancer (NSCLC).

PTPN11 ILK

4.35e-06273230473379
Pubmed

The archetype STYX/dead-phosphatase complexes with a spermatid mRNA-binding protein and is essential for normal sperm production.

STYX CARHSP1

4.35e-06273211842224
Pubmed

Role of Chromatin Structural Changes in Regulating Human CYP3A Ontogeny.

CYP3A7 CYP3A4

4.35e-06273226921389
Pubmed

Molecular mechanisms of polymorphic CYP3A7 expression in adult human liver and intestine.

CYP3A7 CYP3A4

4.35e-06273211940601
Pubmed

Solution structure of the focal adhesion adaptor PINCH LIM1 domain and characterization of its interaction with the integrin-linked kinase ankyrin repeat domain.

LIMS1 ILK

4.35e-06273211078733
Pubmed

Integrin-linked kinase mediates CTGF-induced epithelial to mesenchymal transition in alveolar type II epithelial cells.

ILK CCN2

4.35e-06273225580742
Pubmed

Role of ERK1/2 and PI3-K in the regulation of CTGF-induced ILK expression in HK-2 cells.

ILK CCN2

4.35e-06273217498677
Pubmed

The roles of connective tissue growth factor and integrin-linked kinase in high glucose-induced phenotypic alterations of podocytes.

ILK CCN2

4.35e-06273221913214
Pubmed

The focal adhesion protein PINCH-1 associates with EPLIN at integrin adhesion sites.

LIMA1 LIMS1

4.35e-06273225609703
Pubmed

Expression of CYP3A4 and CYP3A7 in Human Foetal Tissues and its Correlation with Nuclear Receptors.

CYP3A7 CYP3A4

4.35e-06273225689036
Pubmed

Immunohistochemical markers of CYP3A4 and CYP3A7: a new tool towards personalized pharmacotherapy of hepatocellular carcinoma.

CYP3A7 CYP3A4

4.35e-06273227349315
Pubmed

Requirement for PINCH in skeletal myoblast differentiation.

LIMS1 LIMS2

4.35e-06273236385586
Pubmed

Developmental regulation of CYP3A4 and CYP3A7 in Chinese Han population.

CYP3A7 CYP3A4

4.35e-06273227727071
Pubmed

Expression and cyclic variability of CYP3A4 and CYP3A7 isoforms in human endometrium and cervix during the menstrual cycle.

CYP3A7 CYP3A4

4.35e-06273212485945
Pubmed

Role of PINCH and its partner tumor suppressor Rsu-1 in regulating liver size and tumorigenesis.

LIMS1 LIMS2

4.35e-06273224058607
Pubmed

Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis.

LIMA1 GATA3 EIF3H

5.91e-061773324737748
Pubmed

Integrin-linked kinase is required for radial sorting of axons and Schwann cell remyelination in the peripheral nervous system.

LIMS1 ILK LIMS2

8.39e-061973319349584
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

EHBP1 SACS SLCO2B1 DNAH17 TTC21B ZBTB26 ZNF518B UBN2

9.24e-0649373815368895
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

PABIR1 EHBP1 LIMA1 ILK MDN1 MAST4 CLMN AHNAK CCDC18 NSMCE2

1.25e-05861731036931259
Pubmed

PINCH-1 is an obligate partner of integrin-linked kinase (ILK) functioning in cell shape modulation, motility, and survival.

LIMS1 ILK

1.30e-05373214551191
Pubmed

Molecular dissection of the ILK-PINCH-parvin triad reveals a fundamental role for the ILK kinase domain in the late stages of focal-adhesion maturation.

LIMS1 ILK

1.30e-05373219435803
Pubmed

The P450 oxidoreductase genotype is associated with CYP3A activity in vivo as measured by the midazolam phenotyping test.

CYP3A7 CYP3A4

1.30e-05373219801957
Pubmed

Metabolic pathways of inhaled glucocorticoids by the CYP3A enzymes.

CYP3A7 CYP3A4

1.30e-05373223143891
Pubmed

Development of template systems for ligand interactions of CYP3A5 and CYP3A7 and their distinctions from CYP3A4 template.

CYP3A7 CYP3A4

1.30e-05373233866277
Pubmed

Integrin-linked kinase is localized to cell-matrix focal adhesions but not cell-cell adhesion sites and the focal adhesion localization of integrin-linked kinase is regulated by the PINCH-binding ANK repeats.

LIMS1 ILK

1.30e-05373210574708
Pubmed

Cytochrome P450 3A gene variation, steroid hormone serum levels and prostate cancer--The Rotterdam Study.

CYP3A7 CYP3A4

1.30e-05373220621111
Pubmed

Formation and phosphorylation of the PINCH-1-integrin linked kinase-alpha-parvin complex are important for regulation of renal glomerular podocyte adhesion, architecture, and survival.

LIMS1 ILK

1.30e-05373215872073
Pubmed

Contribution of three CYP3A isoforms to metabolism of R- and S-warfarin.

CYP3A7 CYP3A4

1.30e-05373220615193
Pubmed

Effects of hypoxia-inducible factor-1α chemical stabilizer, CoCl(2) and hypoxia on gene expression of CYP3As in human fetal liver cells.

CYP3A7 CYP3A4

1.30e-05373222277676
Pubmed

Chromatin Immunoprecipitation and DNA Sequencing Identified a LIMS1/ILK Pathway Regulated by LMO1 in Neuroblastoma.

LIMS1 ILK

1.30e-05373229695398
Pubmed

Comparison of steroid hormone hydroxylation mediated by cytochrome P450 3A subfamilies.

CYP3A7 CYP3A4

1.30e-05373232001245
Pubmed

Brief research report: Effects of Pinch deficiency on cartilage homeostasis in adult mice.

LIMS1 LIMS2

1.30e-05373236743414
Pubmed

CYP3A Polymorphism and Chronic Mercury Intoxication.

CYP3A7 CYP3A4

1.30e-05373232146629
Pubmed

Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites.

LIMS1 ILK

1.30e-05373212432066
Pubmed

The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cells.

LIMS1 ILK

1.30e-05373210022929
Pubmed

In vitro and in vivo evidence for an inflammatory role of the calcium channel TRPV4 in lung epithelium: Potential involvement in cystic fibrosis.

PLA2G4A TRPV4

1.30e-05373227496898
Pubmed

Synergistic role of retinoic acid signaling and Gata3 during primitive choanae formation.

RDH10 GATA3

1.30e-05373234272563
Pubmed

ILKAP, ILK and PINCH1 control cell survival of p53-wildtype glioblastoma cells after irradiation.

LIMS1 ILK

1.30e-05373226460618
Pubmed

Differences in CYP3A41G genotype distribution and haplotypes of CYP3A4, CYP3A5 and CYP3A7 in 3 Chinese populations.

CYP3A7 CYP3A4

1.30e-05373217582393
Pubmed

Cytochrome P450 3As gene expression and testosterone 6 beta-hydroxylase activity in human fetal membranes and placenta at full term.

CYP3A7 CYP3A4

1.30e-05373220118548
Pubmed

CYP3A7, CYP3A4, and CYP3A5 genetic polymorphisms in recipients rather than donors influence tacrolimus concentrations in the early stages after liver transplantation.

CYP3A7 CYP3A4

1.30e-05373234688813
Pubmed

SHP-2 modulates interleukin-1-induced Ca2+ flux and ERK activation via phosphorylation of phospholipase Cgamma1.

PTPN11 PLCG1

1.30e-05373215563458
Pubmed

The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.

IPO5 LIMS1 MDN1 NSF PYGB GSTO1

1.93e-0526273636880596
Pubmed

Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics.

LIMS1 ILK

2.60e-05473233587032
Pubmed

Tyrosine 1213 of Flt-1 is a major binding site of Nck and SHP-2.

PTPN11 PLCG1

2.60e-0547329600074
Pubmed

Functional molecular imaging of ILK-mediated Akt/PKB signaling cascades and the associated role of beta-parvin.

LIMS1 ILK

2.60e-05473220164304
Pubmed

Histopathology of melanosis coli and determination of its associated genes by comparative analysis of expression microarrays.

CYP3A7 CYP3A4

2.60e-05473226238215
Pubmed

Thymosin beta4 inhibits TNF-alpha-induced NF-kappaB activation, IL-8 expression, and the sensitizing effects by its partners PINCH-1 and ILK.

LIMS1 ILK

2.60e-05473221343177
Pubmed

Allele and genotype frequencies of CYP3A4, CYP3A5, CYP3A7, and GSTP1 gene polymorphisms among mainland Tibetan, Mongolian, Uyghur, and Han Chinese populations.

CYP3A7 CYP3A4

2.60e-05473234689350
Pubmed

CYP3A7, CYP3A5, CYP3A4, and ABCB1 genetic polymorphisms, cyclosporine concentration, and dose requirement in transplant recipients.

CYP3A7 CYP3A4

2.60e-05473218978522
Pubmed

Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair.

LIMS1 ILK

2.60e-05473215565145
Pubmed

The roles of two distinct regions of PINCH-1 in the regulation of cell attachment and spreading.

LIMS1 ILK

2.60e-05473220926685
Pubmed

Non-catalytic signaling by pseudokinase ILK for regulating cell adhesion.

LIMS1 ILK

2.60e-05473230367047
Pubmed

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.

LIMA1 LIMS1 TES ILK AHNAK LIMS2

3.09e-0528573621423176
Pubmed

Proteomic analysis of NMDA receptor-adhesion protein signaling complexes.

PTPN11 NSF PLA2G4A PLCG1

3.33e-058673410862698
Pubmed

Cytochrome P450 isoforms are differently up-regulated in aflatoxin B₁-exposed human lymphocytes and monocytes.

CYP3A7 CYP3A4

4.33e-05573224168324
Pubmed

Association of the insulin receptor with phospholipase C-gamma (PLCgamma) in 3T3-L1 adipocytes suggests a role for PLCgamma in metabolic signaling by insulin.

PTPN11 PLCG1

4.33e-0557329593725
Pubmed

Human cytochrome P450 3A7 has a distinct high catalytic activity for the 16alpha-hydroxylation of estrone but not 17beta-estradiol.

CYP3A7 CYP3A4

4.33e-05573214559847
Pubmed

Genomic organization of the human CYP3A locus: identification of a new, inducible CYP3A gene.

CYP3A7 CYP3A4

4.33e-05573211266076
Pubmed

Differential association of cytoplasmic signalling molecules SHP-1, SHP-2, SHIP and phospholipase C-gamma1 with PECAM-1/CD31.

PTPN11 PLCG1

4.33e-05573210350061
Pubmed

Expression of MYOSIN VIIA in developing mouse cochleovestibular ganglion neurons.

MYO7A GATA3

4.33e-05573231918020
Pubmed

Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites.

CYP3A7 CYP3A4

4.33e-05573211093772
Pubmed

Identification of ILK as a new partner of the ADAM12 disintegrin and metalloprotease in cell adhesion and survival.

LIMS1 ILK

4.33e-05573222767580
Pubmed

Pathways downstream of Shc and Grb2 are required for cell transformation by the tpr-Met oncoprotein.

PTPN11 PLCG1

4.33e-0557328662733
Pubmed

Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.

CYP3A7 CYP3A4 SLCO2B1 ESD GZMA

5.53e-0519373519343046
Pubmed

Rictor and integrin-linked kinase interact and regulate Akt phosphorylation and cancer cell survival.

LIMS1 ILK

6.48e-05673218339839
Pubmed

PINCH2 is a new five LIM domain protein, homologous to PINCHand localized to focal adhesions.

LIMS1 LIMS2

6.48e-05673212651156
Pubmed

Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signalling.

LIMS1 ILK

6.48e-05673223877428
Pubmed

CD99 inhibits CD98-mediated β1 integrin signaling through SHP2-mediated FAK dephosphorylation.

LIMS1 ILK

6.48e-05673226172215
Pubmed

A PINCH-1-Smurf1 signaling axis mediates mechano-regulation of BMPR2 and stem cell differentiation.

LIMS1 ILK

6.48e-05673231578224
Pubmed

Requirement of phospholipase C gamma, the tyrosine phosphatase Syp and the adaptor proteins Shc and Nck for PDGF-induced DNA synthesis: evidence for the existence of Ras-dependent and Ras-independent pathways.

PTPN11 PLCG1

6.48e-0567328890167
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

IPO5 SACS AHNAK CCN2 ZNF518B TTC3

7.19e-0533273637433992
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

IPO5 LIMS1 PTPN11 ILK CLMN CCN2 TTC3

8.43e-0549773723414517
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

IPO5 VRK1 ILK NUP85 SACS AHNAK PLCG1

8.53e-0549873736634849
Pubmed

CFAP45 deficiency causes situs abnormalities and asthenospermia by disrupting an axonemal adenine nucleotide homeostasis module.

DNAH17 DNAH11

9.06e-05773233139725
Pubmed

The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons.

CYP3A7 CYP3A4

9.06e-05773211137287
Pubmed

Association between ABCC2 polymorphism and lopinavir accumulation in peripheral blood mononuclear cells of HIV-infected patients.

CYP3A7 CYP3A4

9.06e-05773219842932
Pubmed

Differences in binding to the ILK complex determines kindlin isoform adhesion localization and integrin activation.

LIMS1 ILK

9.06e-05773225086068
Pubmed

Gab2, a new pleckstrin homology domain-containing adapter protein, acts to uncouple signaling from ERK kinase to Elk-1.

PTPN11 PLCG1

9.06e-05773210391903
Pubmed

iNOS-Derived Nitric Oxide Induces Integrin-Linked Kinase Endocytic Lysosome-Mediated Degradation in the Vascular Endothelium.

LIMS1 ILK

9.06e-05773228546219
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH17 DNAH11

9.06e-05773231178125
GeneFamilyDyneins, axonemal

DNAH10 DNAH17 DNAH11

1.66e-0517543536
GeneFamilyLIM zinc finger domain containing|LIM domain containing

LIMS1 LIMS2

5.23e-0545421163
GeneFamilyCytochrome P450 family 3

CYP3A7 CYP3A4

2.42e-0485421002
GeneFamilyLIM domain containing

LIMA1 LIMS1 TES

7.27e-04595431218
GeneFamilyPhospholipases|C2 domain containing phospholipases

PLA2G4A PLCG1

1.45e-0319542832
GeneFamilyUDP glucuronosyltransferases

UGT2A3 UGT2B10

4.10e-0332542363
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TRANK1 TTC21B TTC3

4.91e-03115543769
GeneFamilyPhospholipases

PLA2G4A PLCG1

6.98e-0342542467
GeneFamilyPDZ domain containing

MAST4 AHNAK LNX1

1.06e-021525431220
GeneFamilyAAA ATPases

MDN1 NSF

1.09e-0253542413
CoexpressionGSE22886_NAIVE_TCELL_VS_NEUTROPHIL_UP

IPO5 PTPN11 TES NUP85 ESD TTC3

1.83e-05199726M4473
CoexpressionGSE19888_CTRL_VS_TCELL_MEMBRANES_ACT_MAST_CELL_PRETREAT_A3R_INH_UP

CYP3A7 EML5 STYX SLCO2B1 ZBTB26 TTC3

1.88e-05200726M7335
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH10 CLMN CCN2 RP1 CEP126 DNAH11

8.21e-071957363486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH10 CLMN CCN2 RP1 CEP126 DNAH11

8.21e-07195736e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCell(00)_Basal-(2)_GFP_FOXI1|(00)_Basal / shred by cell type by condition

LIMA1 LIMS1 PTPN11 GATA3 TTC3 GSTO1

9.24e-0719973619674e1eaeb51e4196d847cb62aa437c852951d3
ToppCell(04)_Interm._basal>secr.-(2)_GFP_FOXI1|(04)_Interm._basal>secr. / shred by cell type by condition

LIMS1 PTPN11 GATA3 SECISBP2 CCN2 TTC3

9.24e-0719973653ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCell356C-Lymphocytic-ILC-ILC-3|ILC / Donor, Lineage, Cell class and subclass (all cells)

FAM228B PTPN11 NSF UBN2

3.10e-0661734d0b33a48ee2faf68b270f9279c630437f3e8b20b
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH10 TRPV4 RP1 CEP126 DNAH11

5.66e-061557355f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH10 TRPV4 RP1 CEP126 DNAH11

5.66e-061557350944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCellBronchial_Biopsy-Immune-T_and_NK|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

MYO7A GATA3 RP1 PLCG1 RECK

8.37e-06168735435b2f238fbb3f50427e8cdecf2220615015153c
ToppCelldroplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRANK1 CLMN CCDC18 CCN2 RP1

9.92e-06174735a0ccda8fd6f55251cdeff24cf66e72e4a31d2104
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAM228B CILP CCDC18 TRPV4 ZNF518B

9.92e-061747351779e67382cb2644534ffb5b9b8f28d32935f4ea
ToppCellCOVID-19_Convalescent|World / Disease Group and Platelet Clusters

PABIR1 SECISBP2 CEP126 NSMCE2 GSTO1

1.02e-05175735e9b1faa4c85537f30306619a2f3ada6c8ef0ac6c
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TES ILK AHNAK CCN2 LIMS2

1.20e-05181735beb2771820956be8b190c0088ae3c4efdb53c897
ToppCelldroplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LIMA1 MYO7A CLMN SLCO2B1 DNAH11

1.48e-0518973598f517af255ef234eefc3ed7e6c1d63331ab8af0
ToppCelldroplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LIMA1 MYO7A CLMN SLCO2B1 DNAH11

1.48e-05189735f7e9b6e6a4de297b660a5b6c9a62f860c147185e
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MDN1 GZMA GATA3 PLCG1 TTC3

1.48e-05189735d05e043d0874b8563b9f5514f6c884b35c603e3a
ToppCellBAL-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRANK1 MAST4 GZMA GATA3 PLCG1

1.52e-0519073555df73c8b696967a925b1772631f6900eff0fa30
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAH10 CCN2 RP1 CEP126 DNAH11

1.52e-051907359ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAH10 CCN2 RP1 CEP126 DNAH11

1.52e-05190735833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCellBAL-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRANK1 MAST4 GZMA GATA3 PLCG1

1.52e-05190735494fbab37305a7f92cddec75b291d42282555f5f
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-Double_negative_Thymocyte,_DN4_(Cd8-,_Cd4-),_some_undergoing_VDJ_recombination_|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TES SALL2 GATA3 KDM6B TTC3

1.52e-051907358f5e71a0861ee4e8f3ce45e8a7f18fb9d6036a3c
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-double_negative_T_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TES SALL2 GATA3 KDM6B TTC3

1.52e-0519073584265be128170cbb08d76e824aa108e07da9c3e5
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP3A4 CLMN RDH10 RP1 DNAH11

1.52e-051907352fdc024d3d673a0134b74b4c5a63afe924995730
ToppCelldroplet-Bladder-nan-3m-Epithelial-basal_bladder_epithelial_cell_(Krt5+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIMA1 MAST4 GATA3 PYGB GSTO1

1.63e-05193735268925bfe85fb94a93a4ff8fe078d692df888140
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH10 CLMN RP1 CEP126 DNAH11

1.63e-05193735ea345d34440b25f65358a53dc72831998d1c3620
ToppCelldroplet-Bladder-nan-3m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIMA1 MAST4 GATA3 PYGB GSTO1

1.63e-05193735ee91a796d0f6d4cee7a93a525689e716fdceeda5
ToppCellfacs-Bladder-nan-3m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAST4 GATA3 PYGB TRPV4 GSTO1

1.68e-051947351531dcace28a14bd700e909a027426a8cee20337
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

MAST4 DNAH10 RP1 CEP126 DNAH11

1.72e-05195735fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

MAST4 DNAH10 RP1 CEP126 DNAH11

1.72e-0519573521dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 CLMN RP1 CEP126 DNAH11

1.72e-0519573579dc031258579ea328181dda33710dd897f1064a
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

MAST4 DNAH10 RP1 CEP126 DNAH11

1.72e-05195735eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCelltumor_Lung-T/NK_cells-Exhausted_Tfh|T/NK_cells / Location, Cell class and cell subclass

LIMA1 LIMS1 MAST4 MYO7A RDH10

1.76e-051967355a0b5aeff7e535781ea2a4c85799bb468afcb6f8
ToppCellSevere-Lymphoid-T-Treg|Severe / Condition, Lineage, Cell class and cell subclass

LIMA1 MAST4 CARHSP1 GZMA GATA3

1.76e-0519673529d4db6816fead2ad9136ef824e0775463b02159
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 CLMN RP1 CEP126 DNAH11

1.80e-0519773591637bdeab85024b5a02d1066f76cb803a2d6420
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH10 CLMN RP1 CEP126 DNAH11

1.80e-0519773571fea4aa6ce96c7693fa94792d08770622873850
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 CLMN RP1 CEP126 DNAH11

1.80e-0519773522c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 CLMN RP1 CEP126 DNAH11

1.80e-051977353bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH10 CCN2 RP1 CEP126 DNAH11

1.80e-05197735e453d085182364ca347cbcc9dc995c62c3353016
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 CLMN RP1 CEP126 DNAH11

1.80e-0519773587db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH10 CCN2 RP1 CEP126 DNAH11

1.80e-05197735d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TES ILK RDH10 CCN2 LIMS2

1.80e-051977355a63c2b824c7d0dbbc706e408459c9b9fe65daaa
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH10 CLMN RP1 CEP126 DNAH11

1.85e-05198735ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellLPS_only-Epithelial_airway-airway_epithelial-Ciliated|LPS_only / Treatment groups by lineage, cell group, cell type

EML5 DNAH10 MYO7A RP1 CEP126

1.85e-051987356d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLMN AHNAK RDH10 RP1 DNAH11

1.85e-05198735d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCell(05)_Secretory-(2)_GFP_FOXI1|(05)_Secretory / shred by cell type by condition

LIMS1 PTPN11 GATA3 CCN2 TTC3

1.89e-05199735d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-CD4+_T_activated|COVID-19_Mild / Disease, condition lineage and cell class

TRANK1 MDN1 MAST4 GATA3 PLCG1

1.94e-05200735d9e8a0d047d4403fb7265fde7448e23a7780785c
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Thalamus / BrainAtlas - Mouse McCarroll V32

TES TRPV4 RP1 PLCG1

6.78e-0513373429b0c2c682c6b97823e7d8d8ba1f5114044b30ba
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MDN1 GDPD3 PLA2G4A ZNF518A

6.78e-05133734f6e9a1301a3379847b215303a9b0c028841e2cc0
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MDN1 GDPD3 PLA2G4A ZNF518A

6.78e-05133734292ecfcadbaf15e0d34a3ab9bf511ab1065888bd
ToppCellcontrol-dn_T|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

LIMA1 LIMS1 CARHSP1 GZMA

9.99e-0514773468258498202c7f580f72c46dd645071835098455
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH10 RP1 CEP126 DNAH11

1.03e-04148734d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH10 RP1 CEP126 DNAH11

1.03e-04148734c8e93b87212f55774223caa385859c566fa1981f
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B0|367C / Donor, Lineage, Cell class and subclass (all cells)

STYX ZER1 CEP126 UBN2

1.05e-0414973441f28138bde45d0b814e116837e5a32b5e80d54a
ToppCellLPS-IL1RA-Epithelial_airway-Ciliated_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH10 RP1 CEP126 DNAH11

1.11e-0415173481cf939ed4df9574fbfff265e109cb9f947d7e6e
ToppCellLPS-IL1RA-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH10 RP1 CEP126 DNAH11

1.11e-041517349cbcbbc22965a9f0be8364e733d205dd64f2a533
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH10 RP1 CEP126 DNAH11

1.20e-041547349ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MDN1 GZMA GATA3 PLCG1

1.20e-04154734ec920cae12ea1d14b6c973f6e903f895f80e3c50
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH10 RP1 CEP126 DNAH11

1.20e-0415473458072ce422d09f2de602580325eaac6c4ec6c136
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STYX GDPD3 DNAH17 GSTO1

1.29e-04157734eea53cf8d8a607264e1ee00b7a97c94bcf2ac80d
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Mesenchymal|GW19 / Sample Type, Dataset, Time_group, and Cell type.

GDPD3 DNAH17 GATA3 RECK

1.35e-04159734f34f2729a3872fbb2939e76ad35d7e25f71b8f57
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

VRK1 GATA3 PLCG1 DNAH11

1.35e-04159734b1d5ebd0c186b6d0279dab20d8f3b4a915acdc1f
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Mesenchymal-Unfolded_protein_responsible_cell|GW19 / Sample Type, Dataset, Time_group, and Cell type.

GDPD3 DNAH17 GATA3 RECK

1.35e-04159734929ed98f6c2ad14e8d5af5c6f11a5a3d4b388cf7
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ILK MDN1 GZMA RECK

1.39e-041607341a9329d8183296f36928bd9e96f10db9f04ce326
ToppCellPND01-03-samps|World / Age Group, Lineage, Cell class and subclass

MDN1 CCN2 KDM6B LIMS2

1.42e-041617341973b112d8d67aacc02751797d0148e7b53bfa66
ToppCellT_cells-TFH-like_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

LIMS1 PTPN11 MYO7A RDH10

1.52e-04164734b10cf59f4cc37ca6cd0ecf71d7de278cc2bdd8b5
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SLCO2B1 ERCC6L2 CEP126 SENP7

1.60e-04166734f62db9d9b6c9dd8f2afcaea0fc5f8c69f50205b2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SACS AHNAK TTC21B PLCG1

1.63e-0416773483969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCelldroplet-Spleen-nan-21m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK GZMA GATA3 CCN2

1.63e-0416773492ddabbe55315856d8ea6f8db1560b6d97636bac
ToppCelldroplet-Liver-LIVER_NPC-30m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TES AHNAK GZMA GATA3

1.67e-04168734110c3c7c322e04a684a19c2b5434a502279fd000
ToppCelldroplet-Liver-LIVER_NPC-30m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TES AHNAK GZMA GATA3

1.67e-04168734735d30cfda1889740bdeb43e39330a52e8f4d599
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 RP1 CEP126 DNAH11

1.71e-041697348bca402e144819cb9a8d431d6bf9429be2fff6d6
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 RP1 CEP126 DNAH11

1.71e-04169734fba841664939c771881ba97f14ef1df6635c04ff
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 RP1 CEP126 DNAH11

1.71e-0416973414aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRANK1 DNAH10 RP1 DNAH11

1.71e-0416973412bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellfacs-Lung-nan-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDHB15 PLA2G4A TRPV4 CCN2

1.75e-041707348e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TES AHNAK GATA3 PLCG1

1.75e-04170734aff226a84e397ab58204325aa9d8b396a881986e
ToppCellfacs-Lung-nan-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDHB15 PLA2G4A TRPV4 CCN2

1.75e-0417073467d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TES AHNAK GATA3 PLCG1

1.75e-041707346af16e6f276aec6389ece99505ba13c7edc4c4fa
ToppCellcontrol-dn_T|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

LIMA1 LIMS1 CARHSP1 GZMA

1.75e-04170734839f62860b4a52d06e6a8fce7632195c7310b89d
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD4_INF-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TES TRANK1 AHNAK GZMA

1.79e-04171734e6dfbd2652b67577c8834c05348f62150637f348
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD4_INF|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TES TRANK1 AHNAK GZMA

1.79e-04171734ddaeb96ce9c9c3bf232b4a42266fa2ee7e8f3f41
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD4_rest-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TES AHNAK GZMA GATA3

1.79e-04171734e1fe07652c10c37191d1471ddaea500f74269e0c
ToppCelldroplet-Marrow-nan-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EHBP1 AHNAK DNAH17 GSTO1

1.87e-041737346d2ceba4f89a228600e2b40aba81bb0eb81578c0
ToppCell390C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

LIMA1 SALL2 SLCO2B1 TRPV4

1.87e-041737341f725ff16e28636b20ef26f3fa9be8b47c89378d
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SACS ZER1 TRPV4 CCN2

1.95e-04175734a5db428b078938627e61b7e944c1e0c1d61ac2da
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CARHSP1 GDPD3 RDH10 LNX1

1.95e-041757348252ddc2ca95071381f0354aefb70c4714828491
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SACS ZER1 TRPV4 CCN2

1.95e-041757348b498eea1ec1c1f27b171025c3d08adf3687bafc
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CARHSP1 GDPD3 RDH10 LNX1

1.95e-041757348ccf60fc469059d7aaf4e6ce54159db2962e0060
ToppCellT_cells-Tph_and_Tfh|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

LIMS1 PTPN11 MYO7A RDH10

2.00e-0417673456c055488e34605d32562571a2fee621b47c9441
ToppCellfacs-Spleen-nan-18m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK GZMA GATA3 RECK

2.00e-04176734a23d484aff5ad094333b2feae9106ca219514711
ToppCelldroplet-Pancreas-Exocrine-24m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLMN PYGB TRPV4 CCN2

2.04e-04177734a5b54792ef948a1e1de66301a60e051250189f59
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GZMA GATA3 ERCC6L2 PLCG1

2.04e-041777349edfb50856f5e10672ab194ce0076d6a190e64de
ToppCelldroplet-Lung-nan-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO7A CLMN SLCO2B1 DNAH11

2.08e-04178734de6cd81e6d58e7687386df163471bf1901b9c0aa
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATA3 PLA2G4A TRPV4 LIMS2

2.08e-041787345cc182e6faa7ba5b88378d2c953be29bbbb95a7e
ToppCellfacs-Lung-Endomucin-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATA3 PLA2G4A TRPV4 LIMS2

2.08e-04178734f9a16bc3f09c35c7d30e3809da024bc2dcf746ed
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLMN RP1 CEP126 DNAH11

2.08e-041787343b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCellT_cells-TFH-like_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

LIMS1 PTPN11 MYO7A RDH10

2.08e-04178734e2ae43e5ec31de6197f2cbd6089f944adbf0a163
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TES ILK CCN2 LIMS2

2.13e-04179734e860dca9b28ac5af61804bfd729cd39257cdb352
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 RP1 CEP126 DNAH11

2.17e-041807341f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCellfacs-Spleen-nan-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK GATA3 PLCG1 RECK

2.17e-04180734407fd8f61a757626e082b6e2eefd3a33276e6b71
ToppCellfacs-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GATA3 PLA2G4A TRPV4 LIMS2

2.22e-0418173472c28baf4fd417ff4a7068603830d55074960144
Drugbeta-naphthoflavone

CYP3A7 CYP3A4 SLCO2B1 ESD UGT2A3 UGT2B10 GSTO1

3.30e-06200727CID000002361
DrugBiliton

DNAH10 MYO7A DNAH17 DNAH11

8.52e-0641724CID000002974
Drugorthovanadate

PTPN11 STYX ACTRT3 MYO7A NSF DNAH17 PYGB PLCG1 DNAH11

9.17e-06435729CID000061672
Drugp-nitroanisole

CYP3A7 CYP3A4 ESD UGT2A3 UGT2B10

1.09e-0592725CID000007485
DrugN'-nitrosonornicotine

GATA3 UGT2B10 PLA2G4A

1.34e-0515723ctd:C008655
Drug1-naphthol

CYP3A7 CYP3A4 ESD UGT2A3 UGT2B10

1.48e-0598725CID000007005
Druggeldanamycin

EHBP1 LIMA1 PTPN11 RDH10 ERCC6L2 UBN2 TTC3 ZNF518A

2.22e-05371728ctd:C001277
DrugSN-38

CYP3A7 CYP3A4 ESD UGT2A3 UGT2B10 RECK

2.58e-05184726CID000104842
Drug5,6-epoxy-8,11,14-eicosatrienoic acid

CYP3A4 TRPV4

2.95e-053722ctd:C040776
Drug17-hydroxypregnenolone sulfate

CYP3A7 CYP3A4

2.95e-053722CID000152971
DrugAC1L1FTZ

CYP3A4 PLA2G4A

2.95e-053722CID000003392
DrugSN-38G

CYP3A4 ESD UGT2A3 UGT2B10

3.67e-0559724CID000443154
Drugbenzphetamine

CYP3A7 CYP3A4 UGT2A3 UGT2B10 KDM6B

3.79e-05119725CID000002341
Drughexobarbital

CYP3A7 CYP3A4 CLMN UGT2A3 UGT2B10

5.18e-05127725CID000003608
Drugvanadyl

PTPN11 DNAH10 MYO7A NSF DNAH17 PLCG1 DNAH11

5.27e-05307727CID000061671
DrugAroclor 1254

CYP3A7 LIMS1 CYP3A4 UGT2A3 UGT2B10 GSTO1

5.84e-05213726CID000040470
Drug5,6-epoxyeicosatrienoic acid

CYP3A7 CYP3A4 PLA2G4A TRPV4

6.42e-0568724CID000001778
Diseaseapolipoprotein B measurement

EHBP1 LIMA1 LIMS1 PTPN11 DNAH10 PYGB RP1 PLCG1 DNAH11

2.65e-05663709EFO_0004615
Diseasetacrolimus measurement

CYP3A7 CYP3A4

3.32e-054702EFO_0008458
Diseaseestrone conjugate measurement

CYP3A7 CYP3A4

3.32e-054702EFO_0007971
Diseasetauro-beta-muricholate measurement

CYP3A7 CYP3A4

5.52e-055702EFO_0800213
Diseaseglyco-beta-muricholate measurement

CYP3A7 CYP3A4

5.52e-055702EFO_0800569
Diseasedehydroisoandrosterone sulfate DHEA-S measurement

CYP3A7 CYP3A4

8.27e-056702EFO_0021119
Diseaseandrostenediol (3beta,17beta) monosulfate (1) measurement

CYP3A7 CYP3A4

8.27e-056702EFO_0800294
Diseaselow density lipoprotein cholesterol measurement, alcohol consumption measurement

EHBP1 ZER1 RP1 DNAH11

9.22e-0599704EFO_0004611, EFO_0007878
Diseaselow density lipoprotein cholesterol measurement, alcohol drinking

EHBP1 ZER1 RP1 DNAH11

1.04e-04102704EFO_0004329, EFO_0004611
DiseaseX-24574 measurement

CYP3A7 CYP3A4

1.16e-047702EFO_0800897
Diseasefibromuscular dysplasia

LIMA1 NSF LNX1

1.58e-0444703EFO_1000938
Diseaseandrostenediol (3beta,17beta) disulfate (1) measurement

CYP3A7 CYP3A4

1.98e-049702EFO_0800278
Disease4-androsten-3alpha,17alpha-diol monosulfate (3) measurement

CYP3A7 CYP3A4

2.47e-0410702EFO_0022090
Disease5alpha-androstan-3beta,17alpha-diol disulfate measurement

CYP3A7 CYP3A4

2.47e-0410702EFO_0800289
DiseaseDNA repair protein RAD51 homolog 4 measurement

CYP3A7 CYP3A4

3.01e-0411702EFO_0801531
Diseaseandrostenediol (3beta,17beta) monosulfate (2) measurement

CYP3A7 CYP3A4

3.01e-0411702EFO_0800295
DiseasePrecursor B-Cell Lymphoblastic Leukemia-Lymphoma

GATA3 CCN2

3.61e-0412702C0023485
Disease5alpha-androstan-3beta,17beta-diol monosulfate (2) measurement

CYP3A7 CYP3A4

3.61e-0412702EFO_0800291
Diseaseandrostenediol (3alpha, 17alpha) monosulfate (3) measurement

CYP3A7 CYP3A4

4.25e-0413702EFO_0800293
Disease5alpha-pregnan-3beta,20beta-diol monosulfate (1) measurement

CYP3A7 CYP3A4

4.25e-0413702EFO_0800284
DiseaseLiver Cirrhosis, Experimental

TES ILK AHNAK GZMA RDH10 PLA2G4A CCN2 RECK

4.86e-04774708C0023893
DiseaseX-21470 measurement

CYP3A7 CYP3A4

4.96e-0414702EFO_0800817
Disease5alpha-androstan-3alpha,17alpha-diol monosulfate measurement

CYP3A7 CYP3A4

4.96e-0414702EFO_0800283
Diseaselow density lipoprotein cholesterol measurement, physical activity

EHBP1 RP1 DNAH11

5.26e-0466703EFO_0003940, EFO_0004611
Disease16a-hydroxy DHEA 3-sulfate measurement

CYP3A7 CYP3A4

5.71e-0415702EFO_0800301
DiseaseX-21410 measurement

CYP3A7 CYP3A4

6.52e-0416702EFO_0800813
Diseaseidiopathic scoliosis (implicated_via_orthology)

PTPN11 DNAH10

6.52e-0416702DOID:0060250 (implicated_via_orthology)
Diseaseandro steroid monosulfate C19H28O6S (1) measurement

CYP3A7 CYP3A4

6.52e-0416702EFO_0800305
Diseaseanthranilic acid measurement

NSMCE2 LNX1

6.52e-0416702EFO_0010460
Disease5alpha-androstan-3alpha,17beta-diol monosulfate (1) measurement

CYP3A7 CYP3A4

8.28e-0418702EFO_0800288
DiseaseLung diseases

CCN2 GSTO1 DNAH11

8.56e-0478703C0024115
Diseasesensorineural hearing loss (implicated_via_orthology)

DNAH17 LNX1

9.24e-0419702DOID:10003 (implicated_via_orthology)
Diseasemetabolonic lactone sulfate measurement

CYP3A7 CYP3A4

9.24e-0419702EFO_0800659
Diseaseetiocholanolone glucuronide measurement

CYP3A7 CYP3A4

9.24e-0419702EFO_0800362
Diseaseandrosterone glucuronide measurement

CYP3A7 CYP3A4

1.03e-0320702EFO_0800317
DiseaseHMG CoA reductase inhibitor use measurement

EHBP1 UGT2B10 RP1 DNAH11

1.08e-03189704EFO_0009932
DiseaseX-24947 measurement

CYP3A7 CYP3A4

1.24e-0322702EFO_0800910
Disease5alpha-androstan-3beta,17beta-diol disulfate measurement

CYP3A7 CYP3A4

1.24e-0322702EFO_0021115
Diseaseepiandrosterone sulfate measurement

CYP3A7 CYP3A4

1.61e-0325702EFO_0021120
Diseasefree cholesterol measurement, very low density lipoprotein cholesterol measurement

EHBP1 DNAH10 PLCG1 DNAH11

1.73e-03215704EFO_0008317, EFO_0008591
DiseaseC-reactive protein measurement

CYP3A7 TES TRANK1 CYP3A4 AHNAK DNAH17 PYGB NSMCE2 DNAH11

2.14e-031206709EFO_0004458
DiseaseCiliopathies

MYO7A TTC21B DNAH11

2.30e-03110703C4277690
Diseaselymphocyte count

CYP3A7 LIMA1 DNAH10 CYP3A4 AHNAK DNAH17 GATA3 ERCC6L2 RNF212B LIMS2

2.30e-0314647010EFO_0004587

Protein segments in the cluster

PeptideGeneStartEntry
VNFPSFLPAFVKKMK

TTC21B

206

Q7Z4L5
PKPLCFMEVLAKEDT

FAM228B

26

P0C875
LNCKMKFAVYLPPKA

ESD

26

P10768
PKLMEVCKEKDFSPE

EIF3H

171

O15372
MAKKPDCLEKVYQLP

ACTRT3

226

Q9BYD9
KMFAVDAKALPQNKP

EFL1

416

Q7Z2Z2
TKQIMLVKKEFPYPC

GZMA

91

P12544
KELACPMPVIFAKAT

DNAH11

4451

Q96DT5
LECPDAKLKGPKFKM

AHNAK

1831

Q09666
FCILFAPKAAMQEKE

ATG2B

1491

Q96BY7
NLKPQEKMFFKSPVE

RNF212B

51

A8MTL3
KMPFINIPVLDIKKC

RECK

391

O95980
FKFMKKFEAVLSEPC

MDN1

3971

Q9NU22
TLKNKFVEFDMKPVC

LIMS2

291

Q7Z4I7
PKAMKKFQAPARETC

LIMA1

376

Q9UHB6
KLLPDDPYEKACQKM

GSTO1

101

P78417
KISDPDLFKMIKFCL

KDM6B

1526

O15054
VCKKDVEINGMFIPK

CYP3A4

376

P08684
KKEKSEMVPSCPFIY

NUP85

41

Q9BW27
NFTCPITKEEMKKPV

NSMCE2

166

Q96MF7
EKDFCPMDRKPLVLQ

LNX1

71

Q8TBB1
NFPFIKICSPDKMIG

NSF

561

P46459
KKCKAANPEMPLSFT

GDPD3

186

Q7L5L3
MPEFETKCNNSKPKK

PTPN11

311

Q06124
PLKRKCEMETEYQPK

PABIR1

201

Q96E09
MICSIQDDVPFKLKP

PCDHB15

381

Q9Y5E8
VGKIMKFKPDCVNVE

IPO5

976

O00410
PPQMKKKCVNGFIMF

MEIOSIN

536

C9JSJ3
FMCNTVFKKIPLKPS

PIPSL

391

A2A3N6
KECLKYQVPLPDSMK

GATA3

181

P23771
CVNMKLFFKDKEPVP

DNAH17

391

Q9UFH2
EIMPDVQDPKFAKCF

CCDC18

1326

Q5T9S5
LPVEFKCPDGEVMKK

CCN2

301

P29279
VSSPPMFVLDKKCEK

CEP126

371

Q9P2H0
TFLPEVAKKFPNMKI

BPI

331

P17213
KICMNEDPAKRPKFD

ILK

426

Q13418
YVSDKKKDMSPPFIC

EHBP1

701

Q8NDI1
EDKEDNLCPVLKPKM

MAST4

1696

O15021
KDKIFVVKMNPYVPD

EML5

816

Q05BV3
VCKKDVEINGMFIPK

CYP3A7

376

P24462
FIPRKPMKCSNEKVV

ERCC6L2

1096

Q5T890
IVMEKFAAKKPPCVA

DNAH10

1006

Q8IVF4
PAFNKFVLMKAVEPK

SALL2

506

Q9Y467
MLPEKLFIPNDFFKK

SACS

3551

Q9NZJ4
GLKECYVFKPKNPDM

PLA2G4A

616

P47712
YVFKPKNPDMEKDCP

PLA2G4A

621

P47712
LKKFQPDLKERFCMN

RP1

2021

P56715
FSKTNMVDLCPKVPK

SENP7

971

Q9BQF6
VMVNDKPVCKPCYVK

TES

341

Q9UGI8
NTCPLPQEMKALFKK

SECISBP2

131

Q96T21
TLKNKFVEFDMKPVC

LIMS1

286

P48059
MKPVCKKCYEKFPLE

LIMS1

296

P48059
PLKPDYCVKQAMKAI

RDH10

266

Q8IZV5
MEDVKLEFPSLPQCK

STYX

1

Q8WUJ0
PISMENPYKEPLKKC

MRPS18C

51

Q9Y3D5
PPSKVFVCDKPESMK

CLMN

346

Q96JQ2
PKPMEFRACYIKVKI

CILP

946

O75339
EVTYKMCSIPPKNEK

CARHSP1

106

Q9Y2V2
QFIQPLECMEKFDKK

WDR47

66

O94967
MKLFLDCLKEFPEKQ

ZER1

571

Q7Z7L7
FPTMLKECSPKKDQK

UBN2

701

Q6ZU65
FFPKEMPKEKRELQF

SLCO2B1

296

O94956
FSPKEPDCFKDIVNM

PYGB

751

P11216
KMLLEKFVEECKFPP

TTC3

631

P53804
ANPMPTFKCAVKALF

PLCG1

786

P19174
FLKCVMPNKTELLKP

ZNF518A

1106

Q6AHZ1
MDKCFPEKNKPGEIA

VRK1

286

Q99986
KPAKALPKEMENFVQ

UGT2A3

281

Q6UWM9
CKPAKPLPKEMEEFV

UGT2B10

281

P36537
PFVFICKNPQEMVVK

TRIP4

536

Q15650
CKNPQEMVVKFPIKG

TRIP4

541

Q15650
NPMACKEILKPNYKS

TRANK1

2241

O15050
FTNIKDLFMKKCPGV

TRPV4

526

Q9HBA0
FIKPKQPMDSKEGCE

ZBTB26

126

Q9HCK0
PKEYQKDVVCIPNKM

ZNF518B

281

Q9C0D4
FFVRCIKPNEFKKPM

MYO7A

631

Q13402