Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsingle-stranded RNA binding

RBMS1 DDX60 PABPC4 U2AF2 CBX4 PABPC1 MSI2 TIA1 PABPC3 PABPC1L DDX11L8

6.87e-1011114911GO:0003727
GeneOntologyMolecularFunctionpoly-pyrimidine tract binding

RBMS1 PABPC4 U2AF2 PABPC1 MSI2 PABPC3 PABPC1L

1.41e-08391497GO:0008187
GeneOntologyMolecularFunctionpoly(A) binding

RBMS1 PABPC4 PABPC1 TIA1 PABPC3 PABPC1L

6.43e-08291496GO:0008143
GeneOntologyMolecularFunctionpoly(U) RNA binding

RBMS1 PABPC4 PABPC1 MSI2 PABPC3 PABPC1L

1.77e-07341496GO:0008266
GeneOntologyMolecularFunctionpoly-purine tract binding

RBMS1 PABPC4 PABPC1 TIA1 PABPC3 PABPC1L

3.00e-07371496GO:0070717
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC9A8 ABCA3 SLC2A8 KCNV2 SLC25A14 SLC25A26 AQP8 RYR2 ABCB1 ABCB4 MFSD14A SLC8A2 SLC7A4 SLC8A3 SLCO4C1 ABCB9 CLCNKA SLC25A40 CLCNKB SV2B KCNH1 SV2A SLC2A6 KCNJ10 SLC26A6

2.10e-06118014925GO:0022857
GeneOntologyMolecularFunctiontransporter activity

SLC9A8 ABCA3 SLC2A8 KCNV2 SLC25A14 SLC25A26 AQP8 RYR2 ABCB1 ABCB4 MFSD14A SLC8A2 SLC7A4 SLC8A3 SLCO4C1 ABCB9 CLCNKA SLC25A40 CLCNKB SV2B KCNH1 SV2A SLC2A6 KCNJ10 SLC26A6

9.86e-06128914925GO:0005215
GeneOntologyMolecularFunctionceramide floppase activity

ABCB1 ABCB4

1.65e-0431492GO:0099038
GeneOntologyMolecularFunctioncalcium:monoatomic cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration

SLC8A2 SLC8A3

1.65e-0431492GO:1905060
GeneOntologyMolecularFunctionpyrophosphatase activity

ABCA3 HSP90B2P ERCC3 DDX60 RAB3D LHPP RHOT2 UPF1 ABCB1 ABCB4 EFTUD2 ABCB9 ENTPD5 DDX41 RAB3A RAB3B DDX11L8

1.79e-0483914917GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

ABCA3 HSP90B2P ERCC3 DDX60 RAB3D LHPP RHOT2 UPF1 ABCB1 ABCB4 EFTUD2 ABCB9 ENTPD5 DDX41 RAB3A RAB3B DDX11L8

1.81e-0484014917GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

ABCA3 HSP90B2P ERCC3 DDX60 RAB3D LHPP RHOT2 UPF1 ABCB1 ABCB4 EFTUD2 ABCB9 ENTPD5 DDX41 RAB3A RAB3B DDX11L8

1.81e-0484014917GO:0016818
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

ABCA3 HSP90B2P ERCC3 DDX60 RAB3D RHOT2 UPF1 ABCB1 ABCB4 EFTUD2 ABCB9 ENTPD5 DDX41 RAB3A RAB3B DDX11L8

2.27e-0477514916GO:0017111
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC9A8 ABCA3 SLC2A8 SLC25A14 SLC25A26 ABCB1 ABCB4 SLC8A2 SLC8A3 SLCO4C1 ABCB9 SLC26A6

2.48e-0447714912GO:0022804
GeneOntologyMolecularFunctionsphingolipid floppase activity

ABCB1 ABCB4

3.29e-0441492GO:0046623
GeneOntologyMolecularFunctionNADPH:quinone reductase activity

ADH4 CRYZL1

3.29e-0441492GO:0003960
GeneOntologyMolecularFunctiongroup III metabotropic glutamate receptor activity

GRM4 GRM8

3.29e-0441492GO:0001642
GeneOntologyMolecularFunctionphosphatidylcholine transporter activity

ABCA3 ABCB1 ABCB4

4.23e-04201493GO:0008525
GeneOntologyMolecularFunctionmyosin V binding

RAB3D RAB3A RAB3B

4.23e-04201493GO:0031489
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA3 ABCB1 ABCB4 ABCB9

4.86e-04491494GO:0140359
GeneOntologyMolecularFunctionantiporter activity

SLC9A8 SLC25A14 SLC25A26 SLC8A2 SLC8A3 SLC26A6

5.97e-041381496GO:0015297
GeneOntologyMolecularFunctionGTP-dependent protein binding

RAB3D RAB3A RAB3B

7.35e-04241493GO:0030742
GeneOntologyMolecularFunctiontriacylglycerol lipase activity

CES1 ABHD2 LIPK

9.33e-04261493GO:0004806
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ABCA3 ABCB1 ABCB4

1.16e-03281493GO:0140326
GeneOntologyMolecularFunctionphosphatidylcholine floppase activity

ABCB1 ABCB4

1.50e-0381492GO:0090554
GeneOntologyMolecularFunctiondehydroascorbic acid transmembrane transporter activity

SLC2A8 SLC2A6

1.50e-0381492GO:0033300
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC9A8 SLC2A8 SLC25A14 SLC25A26 SLC8A2 SLC8A3 SLCO4C1 SLC26A6

1.74e-032961498GO:0015291
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCA3 HSP90B2P ERCC3 DDX60 UPF1 ABCB1 ABCB4 ABCB9 DDX41 DDX11L8

1.78e-0344114910GO:0016887
GeneOntologyMolecularFunctionG protein-coupled glutamate receptor activity

GRM4 GRM8

1.92e-0391492GO:0098988
GeneOntologyMolecularFunctionfructose transmembrane transporter activity

SLC2A8 SLC2A6

1.92e-0391492GO:0005353
GeneOntologyMolecularFunctionadenylate cyclase inhibiting G protein-coupled glutamate receptor activity

GRM4 GRM8

1.92e-0391492GO:0001640
GeneOntologyMolecularFunctioncalcium:sodium antiporter activity

SLC8A2 SLC8A3

2.39e-03101492GO:0005432
GeneOntologyBiologicalProcesstransepithelial transport

AQP8 ABCB1 CLCNKA CLCNKB SLC26A6

7.87e-06381505GO:0070633
GeneOntologyBiologicalProcesscalcium ion transport into cytosol

RYR2 LHCGR SLC8A2 SLC8A3 CD4

1.30e-05421505GO:0060402
GeneOntologyBiologicalProcesstransepithelial chloride transport

CLCNKA CLCNKB SLC26A6

4.36e-05101503GO:0030321
DomainPolyA

PABPC4 PABPC1 PABPC3 PABPC1L

1.68e-0851444SM00517
Domain-

PABPC4 PABPC1 PABPC3 PABPC1L

1.68e-08514441.10.1900.10
DomainPABP

PABPC4 PABPC1 PABPC3 PABPC1L

1.68e-0851444PF00658
DomainPABP_1234

PABPC4 PABPC1 PABPC3 PABPC1L

1.68e-0851444IPR006515
DomainPABC

PABPC4 PABPC1 PABPC3 PABPC1L

1.68e-0851444PS51309
DomainPABP_HYD

PABPC4 PABPC1 PABPC3 PABPC1L

1.68e-0851444IPR002004
DomainRRM_1

PABPC4 PABPC1 TIA1 PABPC3 PABPC1L

7.65e-07231445SM00361
DomainRRM_dom_euk

PABPC4 PABPC1 TIA1 PABPC3 PABPC1L

7.65e-07231445IPR003954
DomainSugar_transporter_CS

SLC2A8 MFSD14A SV2B SV2A SLC2A6

4.33e-06321445IPR005829
DomainRRM_1

CELF6 PTBP2 RBMS1 PABPC4 U2AF2 PABPC1 MSI2 TIA1 PABPC3 PABPC1L

4.96e-0620814410PF00076
DomainRRM

CELF6 PTBP2 RBMS1 PABPC4 U2AF2 PABPC1 MSI2 TIA1 PABPC3 PABPC1L

7.22e-0621714410SM00360
DomainRRM_dom

CELF6 PTBP2 RBMS1 PABPC4 U2AF2 PABPC1 MSI2 TIA1 PABPC3 PABPC1L

1.07e-0522714410IPR000504
DomainRRM

CELF6 PTBP2 RBMS1 PABPC4 U2AF2 PABPC1 MSI2 TIA1 PABPC3 PABPC1L

1.20e-0523014410PS50102
Domain-

CELF6 PTBP2 RBMS1 PABPC4 U2AF2 PABPC1 MSI2 TIA1 PABPC3 PABPC1L

2.00e-05244144103.30.70.330
DomainNucleotide-bd_a/b_plait

CELF6 PTBP2 RBMS1 PABPC4 U2AF2 PABPC1 MSI2 TIA1 PABPC3 PABPC1L

3.22e-0525814410IPR012677
DomainCl_channel-K

CLCNKA CLCNKB

5.90e-0521442IPR002250
DomainMFS_sugar_transport-like

SLC2A8 SV2B SV2A SLC2A6

1.65e-04361444IPR005828
DomainSugar_tr

SLC2A8 SV2B SV2A SLC2A6

1.65e-04361444PF00083
DomainSV2

SV2B SV2A

1.76e-0431442IPR022308
DomainNa_Ca_Ex

SLC8A2 SLC8A3

1.76e-0431442IPR004836
DomainNa_Ca_Ex_C-exten

SLC8A2 SLC8A3

1.76e-0431442IPR032452
DomainPentapeptide_4

SV2B SV2A

1.76e-0431442PF13599
DomainNa_Ca_ex_C

SLC8A2 SLC8A3

1.76e-0431442PF16494
DomainMFS

SLC2A8 MFSD14A SLCO4C1 SV2B SV2A SLC2A6

1.90e-041081446PS50850
DomainABC_transporter_CS

ABCA3 ABCB1 ABCB4 ABCB9

3.02e-04421444IPR017871
Domain5peptide_repeat

SV2B SV2A

3.51e-0441442IPR001646
DomainABC_tran

ABCA3 ABCB1 ABCB4 ABCB9

5.07e-04481444PF00005
DomainABC_TRANSPORTER_2

ABCA3 ABCB1 ABCB4 ABCB9

5.07e-04481444PS50893
DomainABC_TRANSPORTER_1

ABCA3 ABCB1 ABCB4 ABCB9

5.49e-04491444PS00211
DomainAminotrans_3

PHYKPL AGXT2

5.81e-0451442IPR005814
DomainAminotran_3

PHYKPL AGXT2

5.81e-0451442PF00202
DomainAA_TRANSFER_CLASS_3

PHYKPL AGXT2

5.81e-0451442PS00600
DomainABC_transporter-like

ABCA3 ABCB1 ABCB4 ABCB9

5.93e-04501444IPR003439
DomainMFS_dom

SLC2A8 MFSD14A SLCO4C1 SV2B SV2A SLC2A6

6.05e-041341446IPR020846
DomainABC_membrane

ABCB1 ABCB4 ABCB9

8.07e-04241443PF00664
DomainSUGAR_TRANSPORT_1

SLC2A8 MFSD14A SLC2A6

8.07e-04241443PS00216
DomainFN3_dom

COL6A3 CMYA5 PTPRZ1 IL3RA IL6ST CDON MYBPC3

1.20e-032091447IPR003961
DomainABC_TM1F

ABCB1 ABCB4 ABCB9

1.28e-03281443PS50929
DomainABC1_TM_dom

ABCB1 ABCB4 ABCB9

1.28e-03281443IPR011527
DomainGPCR_3_mtglu_rcpt

GRM4 GRM8

1.60e-0381442IPR000162
DomainHelicase/UvrB_N

ERCC3 UPF1

1.60e-0381442IPR006935
DomainCalx_beta

SLC8A2 SLC8A3

1.60e-0381442SM00237
DomainVIT

ITIH1 VWA5A

1.60e-0381442PF08487
DomainVIT

ITIH1 VWA5A

1.60e-0381442SM00609
DomainResIII

ERCC3 UPF1

1.60e-0381442PF04851
Domain-

ABCA3 ERCC3 DDX60 RAB3D RHOT2 UPF1 ABCB1 ABCB4 EFTUD2 ABCB9 AK2 DDX41 RAB3A RAB3B

1.90e-03746144143.40.50.300
DomainCalx_beta

SLC8A2 SLC8A3

2.05e-0391442IPR003644
DomainCl-channel_core

CLCNKA CLCNKB

2.05e-0391442IPR014743
Domain-

CLCNKA CLCNKB

2.05e-03914421.10.3080.10
DomainVoltage_CLC

CLCNKA CLCNKB

2.05e-0391442PF00654
DomainCl-channel_volt-gated

CLCNKA CLCNKB

2.05e-0391442IPR001807
DomainNaCa_Exmemb

SLC8A2 SLC8A3

2.05e-0391442IPR004837
DomainNa_Ca_ex

SLC8A2 SLC8A3

2.05e-0391442PF01699
DomainCalx-beta

SLC8A2 SLC8A3

2.05e-0391442PF03160
DomainVIT

ITIH1 VWA5A

2.55e-03101442PS51468
DomainVIT

ITIH1 VWA5A

2.55e-03101442IPR013694
DomainIL6Ra-bind

IL3RA IL6ST

3.10e-03111442PF09240
DomainTypeI_recpt_CBD

IL3RA IL6ST

3.10e-03111442IPR015321
DomainFN3

COL6A3 CMYA5 PTPRZ1 IL6ST CDON MYBPC3

3.14e-031851446SM00060
Domain-

PHYKPL AGXT2 SGPL1

3.35e-033914433.40.640.10
DomainPyrdxlP-dep_Trfase

PHYKPL AGXT2 SGPL1

3.86e-03411443IPR015424
DomainPyrdxlP-dep_Trfase_major_sub1

PHYKPL AGXT2 SGPL1

3.86e-03411443IPR015421
DomainNCD3G

GRM4 GRM8

4.36e-03131442PF07562
DomainGPCR_3_9-Cys_dom

GRM4 GRM8

4.36e-03131442IPR011500
DomainFN3

COL6A3 CMYA5 PTPRZ1 IL6ST CDON MYBPC3

4.49e-031991446PS50853
DomainSugar/inositol_transpt

SLC2A8 SLC2A6

5.06e-03141442IPR003663
DomainGPCR_3_CS

GRM4 GRM8

5.06e-03141442IPR017979
DomainP-loop_NTPase

ABCA3 ERCC3 DDX60 RAB3D RHOT2 UPF1 ABCB1 ABCB4 EFTUD2 ABCB9 AK2 DDX41 RAB3A RAB3B

5.94e-0384814414IPR027417
DomainCBS

CLCNKA CLCNKB

6.60e-03161442SM00116
DomainPKS_ER

ADH4 CRYZL1

6.60e-03161442IPR020843
DomainADH_N

ADH4 CRYZL1

6.60e-03161442PF08240
DomainPKS_ER

ADH4 CRYZL1

6.60e-03161442SM00829
DomainADH_N

ADH4 CRYZL1

6.60e-03161442IPR013154
DomainSUGAR_TRANSPORT_2

SLC2A8 SLC2A6

7.44e-03171442PS00217
PathwayWP_MRNA_PROCESSING

CELF6 PCBP3 PTBP2 RBMS1 PABPC4 U2AF2 PABPC1 ABCB4 MSI2 EFTUD2 TIA1 PABPC3 LTV1 DDX41

3.84e-0545112314MM15946
Pubmed

The RNA recognition motif protein RBM11 is a novel tissue-specific splicing regulator.

U2AF2 PABPC1 TIA1 PABPC3

7.03e-0810151421984414
Pubmed

Embryonic Poly(A)-Binding Protein Is Required During Early Stages of Mouse Oocyte Development for Chromatin Organization, Transcriptional Silencing, and Meiotic Competence.

PABPC1 PABPC3 PABPC1L

8.02e-083151326134869
Pubmed

Superovulation alters embryonic poly(A)-binding protein (Epab) and poly(A)-binding protein, cytoplasmic 1 (Pabpc1) gene expression in mouse oocytes and early embryos.

PABPC1 PABPC3 PABPC1L

8.02e-083151325034140
Pubmed

The poly(A)-binding protein genes, EPAB, PABPC1, and PABPC3 are differentially expressed in infertile men with non-obstructive azoospermia.

PABPC1 PABPC3 PABPC1L

8.02e-083151326843391
Pubmed

Nuclear relocalisation of cytoplasmic poly(A)-binding proteins PABP1 and PABP4 in response to UV irradiation reveals mRNA-dependent export of metazoan PABPs.

PABPC4 PABPC1 PABPC3

8.02e-083151321940797
Pubmed

Epab and Pabpc1 are differentially expressed during male germ cell development.

PABPC1 PABPC3 PABPC1L

8.02e-083151322814100
Pubmed

Epab is dispensable for mouse spermatogenesis and male fertility.

PABPC1 PABPC3 PABPC1L

8.02e-083151324599567
Pubmed

Epab and Pabpc1 are differentially expressed in the postnatal mouse ovaries.

PABPC1 PABPC3 PABPC1L

8.02e-083151325370180
Pubmed

SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.

PTBP2 RBMS1 PABPC4 U2AF2 RPSA UPF1 CMYA5 PABPC1 MSI2 TIA1

2.12e-072581511037794589
Pubmed

Rab3 proteins involved in vesicle biogenesis and priming in embryonic mouse chromaffin cells.

RAB3D RAB3A RAB3B

3.20e-074151320716109
Pubmed

Localization versus function of Rab3 proteins. Evidence for a common regulatory role in controlling fusion.

RAB3D RAB3A RAB3B

3.20e-074151312167638
Pubmed

A complete genetic analysis of neuronal Rab3 function.

RAB3D RAB3A RAB3B

3.20e-074151315269275
Pubmed

An embryonic poly(A)-binding protein (ePAB) is expressed in mouse oocytes and early preimplantation embryos.

PABPC1 PABPC3 PABPC1L

3.20e-074151315630085
Pubmed

Rab3 superprimes synaptic vesicles for release: implications for short-term synaptic plasticity.

RAB3D RAB3A RAB3B

3.20e-074151316436611
Pubmed

cTag-PAPERCLIP Reveals Alternative Polyadenylation Promotes Cell-Type Specific Protein Diversity and Shifts Araf Isoforms with Microglia Activation.

PTBP2 PABPC1 PABPC3

3.20e-074151328910620
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

PCBP3 RBMS1 PABPC4 RAB3D RPSA AHCYL2 MED1 PABPC1 MSI2 EFTUD2 IGF2R PABPC3 PABPC1L LTV1 DDX41 RAB3A RAB3B HCK NUP153

6.80e-0711531511929845934
Pubmed

Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.

IMPA1 PTBP2 RBMS1 PABPC4 U2AF2 RPSA RHOT2 UPF1 SSR1 PABPC1 MSI2 EFTUD2 TIA1 LTV1 CRYZL1

6.95e-077251511527025967
Pubmed

Tctex-1, a novel interaction partner of Rab3D, is required for osteoclastic bone resorption.

RAB3D RAB3A RAB3B

7.97e-075151321262767
Pubmed

HIV- 1 protease inhibits Cap- and poly(A)-dependent translation upon eIF4GI and PABP cleavage.

PABPC4 PABPC1 PABPC3

7.97e-075151319956697
Pubmed

MKRN3-mediated ubiquitination of Poly(A)-binding proteins modulates the stability and translation of GNRH1 mRNA in mammalian puberty.

PABPC4 PABPC1 PABPC3

7.97e-075151333744966
Pubmed

Rab3a is involved in transport of synaptic vesicles to the active zone in mouse brain nerve terminals.

RAB3D RAB3A RAB3B

7.97e-075151311598194
Pubmed

Embryonic Poly(A)-Binding Protein (EPAB) Is Required for Granulosa Cell EGF Signaling and Cumulus Expansion in Female Mice.

PABPC1 PABPC3 PABPC1L

7.97e-075151326492470
Pubmed

Noc2 is essential in normal regulation of exocytosis in endocrine and exocrine cells.

RAB3D RAB3A RAB3B

7.97e-075151315159548
Pubmed

Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.

ABCA3 PABPC4 RPSA UPF1 SSR1 PIGU PABPC1 IGF2R SGPL1 CNOT1 NUP153

8.27e-073751511132788342
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

PCBP3 PTBP2 RBMS1 PABPC4 U2AF2 RPSA CBX4 HEATR1 MED1 PABPC1 CIC EFTUD2 RIF1 PABPC3 DDX41 MGA NUP153

9.56e-079541511736373674
Pubmed

The RAB3-RIM Pathway Is Essential for the Release of Neuromodulators.

RAB3D RAB3A RAB3B

1.59e-066151331679900
Pubmed

The eukaryotic polypeptide chain releasing factor (eRF3/GSPT) carrying the translation termination signal to the 3'-Poly(A) tail of mRNA. Direct association of erf3/GSPT with polyadenylate-binding protein.

PABPC4 PABPC1 PABPC3

1.59e-066151310358005
Pubmed

Rab3D is not required for exocrine exocytosis but for maintenance of normally sized secretory granules.

RAB3D RAB3A RAB3B

1.59e-066151312192047
Pubmed

Embryonic poly(A)-binding proteinĀ is differently expressed and interacts with the messenger RNAs in the mouse oocytes and early embryos.

PABPC1 PABPC3 PABPC1L

1.59e-066151330302808
Pubmed

Rep15 interacts with several Rab GTPases and has a distinct fold for a Rab effector.

RAB3D RAB3A RAB3B

2.77e-067151335871249
Pubmed

E3 ligase MKRN3 is a tumor suppressor regulating PABPC1 ubiquitination in non-small cell lung cancer.

UPF1 PABPC1 PABPC3

2.77e-067151334143182
Pubmed

Genetic imbalances in preleukemic thymuses.

RPSA PABPC1 PABPC3

2.77e-067151311322760
Pubmed

Chromosomal localization of three human poly(A)-binding protein genes and four related pseudogenes.

PABPC4 PABPC1 PABPC3

2.77e-067151310543404
Pubmed

NMD abnormalities during brain development in the Fmr1-knockout mouse model of fragile X syndrome.

UPF1 PABPC1 PABPC3

2.77e-067151334784943
Pubmed

Mono-ubiquitination of Rabphilin 3A by UBE3A serves a non-degradative function.

RAB3D RAB3A RAB3B

2.77e-067151333542309
Pubmed

A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.

CELF6 PCBP3 PTBP2 RBMS1 PABPC4 U2AF2 PABPC1 MSI2 TIA1 PABPC3

3.10e-063471511016033648
Pubmed

Embryonic poly(A)-binding protein (EPAB) is required for oocyte maturation and female fertility in mice.

PABPC1 PABPC3 PABPC1L

4.42e-068151322621333
Pubmed

RNA binding proteins co-localize with small tau inclusions in tauopathy.

PCBP3 RAB3D U2AF2 PABPC1 BDH1 SLC8A2 TIA1 SV2B PABPC3

4.44e-06283151930068389
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

SEMA4F ERCC3 EMC1 RBMS1 PABPC4 TRMT1 HEATR1 UPF1 PABPC1 SIL1 IGF2R VPS35L CHPF2 NUP153

5.76e-067541511433060197
Pubmed

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3.

HSP90B2P PCBP3 IMPA1 PTBP2 RPSA UPF1 PABPC1 TIA1 SV2B SV2A PABPC3 RAB3A

5.77e-065521511236293380
Pubmed

RNA binding protein RBM46 regulates mitotic-to-meiotic transition in spermatogenesis.

UPF1 PABPC1 PABPC3

6.61e-069151336001654
Pubmed

Embryonic poly(A)-binding protein is required at the preantral stage of mouse folliculogenesis for oocyte-somatic communication.

PABPC1 PABPC3 PABPC1L

6.61e-069151328203794
Pubmed

Rearrangement of the Protein Phosphatase 1 Interactome During Heart Failure Progression.

PABPC4 TRMT1 RPSA BCKDHB PABPC1 EFTUD2 ADPRHL1

1.17e-05174151729669786
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

PTBP2 RBMS1 PABPC4 U2AF2 RPSA HEATR1 UPF1 PABPC1 MSI2 EFTUD2 BUD23 TIA1 DDX41 CNOT1

1.24e-058071511422681889
Pubmed

miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifs.

PABPC4 PABPC1 CNOT1

1.29e-0511151321984184
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

ERCC3 PCBP3 RBMS1 DDX60 PABPC4 U2AF2 RPSA UPF1 MED1 PABPC1 MGA RAB3B CNOT1

1.79e-057241511336232890
Pubmed

Use of a peptide mimotope to guide the humanization of MRK-16, an anti-P-glycoprotein monoclonal antibody.

ABCB1 ABCB4

1.87e-052151210488067
Pubmed

Preferential involvement of Na⁺/Ca²⁺ exchanger type-1 in the brain damage caused by transient focal cerebral ischemia in mice.

SLC8A2 SLC8A3

1.87e-052151223137542
Pubmed

SV2 renders primed synaptic vesicles competent for Ca2+ -induced exocytosis.

SV2B SV2A

1.87e-052151219176798
Pubmed

Multidrug resistance gene expression and ABCB1 SNPs in plasma cell myeloma.

ABCB1 ABCB4

1.87e-052151221705081
Pubmed

The ClC-K2 Chloride Channel Is Critical for Salt Handling in the Distal Nephron.

CLCNKA CLCNKB

1.87e-052151227335120
Pubmed

The role of different P-glycoproteins in hepatobiliary secretion of fluorescently labeled short-chain phospholipids.

ABCB1 ABCB4

1.87e-052151210552998
Pubmed

Differential Coupling of Binding, ATP Hydrolysis, and Transport of Fluorescent Probes with P-Glycoprotein in Lipid Nanodiscs.

ABCB1 ABCB4

1.87e-052151228441502
Pubmed

Genetic dissection of the function of mammalian P-glycoproteins.

ABCB1 ABCB4

1.87e-05215129196326
Pubmed

Receptor-type protein tyrosine phosphatase beta (RPTP-beta) directly dephosphorylates and regulates hepatocyte growth factor receptor (HGFR/Met) function.

MET PTPRZ1

1.87e-052151221454675
Pubmed

Assignment of the genes encoding the human chloride channels, CLCNKA and CLCNKB, to 1p36 and of CLCN3 to 4q32-q33 by in situ hybridization.

CLCNKA CLCNKB

1.87e-05215128812470
Pubmed

Na+/Ca2+ exchanger mediates cold Ca2+ signaling conserved for temperature-compensated circadian rhythms.

SLC8A2 SLC8A3

1.87e-052151233931447
Pubmed

Effects of cellular, chemical, and pharmacological chaperones on the rescue of a trafficking-defective mutant of the ATP-binding cassette transporter proteins ABCB1/ABCB4.

ABCB1 ABCB4

1.87e-052151222184139
Pubmed

Associations between CLCNKA_B tag SNPs with essential hypertension and interactions between genetic and environmental factors in an island population in China.

CLCNKA CLCNKB

1.87e-052151225919862
Pubmed

Synaptic vesicle protein 2 binds adenine nucleotides.

SV2B SV2A

1.87e-052151218524768
Pubmed

Isolation and expression of a complementary DNA that confers multidrug resistance.

ABCB1 ABCB4

1.87e-05215123022150
Pubmed

Mammalian multidrug-resistance gene: correlation of exon organization with structural domains and duplication of an ancestral gene.

ABCB1 ABCB4

1.87e-05215122570420
Pubmed

MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine.

ABCB1 ABCB4

1.87e-05215128898203
Pubmed

Cell-Autonomous Constitutive gp130 Signaling in T Cells Amplifies TH17 Cell Responses and Causes Severe Lung Inflammation.

CD4 IL6ST

1.87e-052151237058116
Pubmed

Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism.

SLC8A2 SLC8A3

1.87e-052151219667209
Pubmed

Differential overexpression of three mdr gene family members in multidrug-resistant J774.2 mouse cells. Evidence that distinct P-glycoprotein precursors are encoded by unique mdr genes.

ABCB1 ABCB4

1.87e-05215122473069
Pubmed

Common genetic variation and risk of gallbladder cancer in India: a case-control genome-wide association study.

ABCB1 ABCB4

1.87e-052151228274756
Pubmed

The solution structure of HIV-1 Nef reveals an unexpected fold and permits delineation of the binding surface for the SH3 domain of Hck tyrosine protein kinase.

CD4 HCK

1.87e-05215128599760
Pubmed

A missense mutation in ABCB4 gene involved in progressive familial intrahepatic cholestasis type 3 leads to a folding defect that can be rescued by low temperature.

ABCB1 ABCB4

1.87e-052151219185004
Pubmed

RNA-seq of 272 gliomas revealed a novel, recurrent PTPRZ1-MET fusion transcript in secondary glioblastomas.

MET PTPRZ1

1.87e-052151225135958
Pubmed

Expanding Genotype-Phenotype Correlation of CLCNKA and CLCNKB Variants Linked to Hearing Loss.

CLCNKA CLCNKB

1.87e-052151238069401
Pubmed

Molecular design, functional characterization and structural basis of a protein inhibitor against the HIV-1 pathogenicity factor Nef.

CD4 HCK

1.87e-052151221625496
Pubmed

Transcriptome-wide analysis uncovers the targets of the RNA-binding protein MSI2 and effects of MSI2's RNA-binding activity on IL-6 signaling.

MSI2 IL6ST

1.87e-052151230126842
Pubmed

The promoter of the Poly(A) binding protein 2 (Pabp2) retroposon is derived from the 5'-untranslated region of the Pabp1 progenitor gene.

PABPC1 PABPC3

1.87e-052151210534404
Pubmed

Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression.

ABCB1 ABCB4

1.87e-052151218215618
Pubmed

The Distribution of the Genotypes of ABCB1 and CES1 Polymorphisms in Kazakhstani Patients with Atrial Fibrillation Treated with DOAC.

CES1 ABCB1

1.87e-052151237372371
Pubmed

A regulatory calcium-binding site at the subunit interface of CLC-K kidney chloride channels.

CLCNKA CLCNKB

1.87e-052151220805576
Pubmed

Absence of LTB4/BLT1 axis facilitates generation of mouse GM-CSF-induced long-lasting antitumor immunologic memory by enhancing innate and adaptive immune systems.

LTB4R KNG1

1.87e-052151222936657
Pubmed

Glycosylated SV2A and SV2B mediate the entry of botulinum neurotoxin E into neurons.

SV2B SV2A

1.87e-052151218815274
Pubmed

Signaling through a novel domain of gp130 mediates cell proliferation and activation of Hck and Erk kinases.

HCK IL6ST

1.87e-052151211689697
Pubmed

Nucleotide sequence of a mouse testis poly(A) binding protein cDNA.

PABPC1 PABPC3

1.87e-05215121630930
Pubmed

Adenosinergic signaling inhibits oxalate transport by human intestinal Caco2-BBE cells through the A2B adenosine receptor.

ADORA2B SLC26A6

1.87e-052151230020825
Pubmed

Inhibition of ABCB1 Overcomes Cancer Stem Cell-like Properties and Acquired Resistance to MET Inhibitors in Non-Small Cell Lung Cancer.

ABCB1 MET

1.87e-052151226351321
Pubmed

Brain contains two forms of synaptic vesicle protein 2.

SV2B SV2A

1.87e-05215127681585
Pubmed

Human carboxylesterase 1A2 expressed from carboxylesterase 1A1 and 1A2 genes is a potent predictor of CPT-11 cytotoxicity in vitro.

CES1P1 CES1

1.87e-052151217264798
Pubmed

Salt wasting and deafness resulting from mutations in two chloride channels.

CLCNKA CLCNKB

1.87e-052151215044642
Pubmed

What have we learnt thus far from mice with disrupted P-glycoprotein genes?

ABCB1 ABCB4

1.87e-05215128763339
Pubmed

Lack of hepatic c-Met and gp130 expression is associated with an impaired antibacterial response and higher lethality after bile duct ligation.

MET IL6ST

1.87e-052151222986785
Pubmed

Developmental expression of poly(A) binding protein mRNAs during spermatogenesis in the mouse.

PABPC1 PABPC3

1.87e-05215127893484
Pubmed

High-sensitive clinical diagnostic method for PTPRZ1-MET and the characteristic protein structure contributing to ligand-independent MET activation.

MET PTPRZ1

1.87e-052151233645009
Pubmed

Two highly homologous members of the ClC chloride channel family in both rat and human kidney.

CLCNKA CLCNKB

1.87e-05215128041726
Pubmed

Biliary secretion of alpha-tocopherol and the role of the mdr2 P-glycoprotein in rats and mice.

ABCB1 ABCB4

1.87e-05215129473291
Pubmed

A cytoplasmic domain mutation in ClC-Kb affects long-distance communication across the membrane.

CLCNKA CLCNKB

1.87e-052151218648499
Pubmed

The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues.

ABCB1 ABCB4

1.87e-05215122471060
Pubmed

CCR2 and DPP9 expression in the peripheral blood of COVID-19 patients: Influences of the disease severity and gender.

CCR2 DPP9

1.87e-052151235131543
Pubmed

Regulatory effects of genomic translocations at the human carboxylesterase-1 (CES1) gene locus.

CES1P1 CES1

1.87e-052151226871237
Pubmed

Cloning, tissue distribution, and intrarenal localization of ClC chloride channels in human kidney.

CLCNKA CLCNKB

1.87e-05215128544406
Pubmed

Characterization of two cytoplasmic poly(A)-binding proteins, PABPC1 and PABPC2, in mouse spermatogenic cells.

PABPC1 PABPC3

1.87e-052151219020299
Pubmed

MDR1 and MDR3 genes and drug resistance to cisplatin of ovarian cancer cells.

ABCB1 ABCB4

1.87e-052151218231753
Pubmed

Targeting kidney CLC-K channels: pharmacological profile in a human cell line versus Xenopus oocytes.

CLCNKA CLCNKB

1.87e-052151224863058
GeneFamilyRNA binding motif containing

CELF6 PTBP2 RBMS1 PABPC4 U2AF2 PABPC1 MSI2 TIA1 PABPC3 PABPC1L

4.15e-0721310410725
GeneFamilySolute carriers

SLC9A8 SLC2A8 SLC25A14 SLC25A26 SLC8A2 SLC7A4 SLC8A3 SLCO4C1 SLC25A40 SLC2A6 SLC26A6

1.70e-0539510411752
GeneFamilyATP binding cassette subfamily B

ABCB1 ABCB4 ABCB9

2.95e-05111043806
GeneFamilyGlutamate metabotropic receptors|Protein phosphatase 1 regulatory subunits

GRM4 GRM8

8.97e-0481042281
GeneFamilyChloride voltage-gated channels

CLCNKA CLCNKB

1.43e-03101042302
GeneFamilyFibronectin type III domain containing

CMYA5 PTPRZ1 IL6ST CDON MYBPC3

2.32e-031601045555
CoexpressionUEDA_PERIFERAL_CLOCK

CES1 RBMS1 AQP8 ABCB4 ADH4 UBR3 AK2 CNOT1

7.00e-061711518M12498
CoexpressionUEDA_PERIFERAL_CLOCK

CES1 RBMS1 AQP8 ABCB4 ADH4 UBR3 AK2 CNOT1

9.02e-061771518MM1145
ToppCellfacs-Heart-LA/RA-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PABPC4 SLC25A26 CMYA5 RYR2 SV2B ADPRHL1 RAB3B MYBPC3

2.54e-07188150890dc0e15798d0b984518ad58c7e416e30aff687a
ToppCellfacs-Heart-LA/RA-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PABPC4 SLC25A26 CMYA5 RYR2 SV2B ADPRHL1 RAB3B MYBPC3

2.54e-071881508f63dfd076ced81013918363282ae25cbbd8948ae
ToppCellfacs-Heart-LA/RA-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PABPC4 SLC25A26 CMYA5 RYR2 SV2B ADPRHL1 RAB3B MYBPC3

2.54e-0718815080554d542149cef654ff1e5e32dfbffd8990b52bd
ToppCellfacs-Heart-LA/RA-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PABPC4 SLC25A26 CMYA5 RYR2 SV2B ADPRHL1 RAB3B MYBPC3

2.64e-071891508a08b2d0fa35ffa510050ecffdc68e1b79bbe1632
ToppCellfacs-Heart-LA/RA|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PABPC4 SLC25A26 CMYA5 RYR2 SV2B ADPRHL1 RAB3B MYBPC3

2.64e-071891508efa913d9c16fc32166b484d92b6449e8a0c59e03
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PABPC4 SLC25A26 CMYA5 PGM5 ADPRHL1 RAB3A RAB3B

1.81e-061701507d99f61aa85ea3f775165cb433421e6f1cda4f96b
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PABPC4 SLC25A26 CMYA5 PGM5 ADPRHL1 RAB3A RAB3B

1.81e-061701507615cf9639c66b3fbd984ebe3f345280005d3c38a
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-8|TCGA-Liver / Sample_Type by Project: Shred V9

PHYKPL AQP8 BDH1 ABCB4 NDUFAF1 ENTPD5 IMMP2L

1.89e-061711507c4a919fe3d56ae6df2fcab6686abacc10befc053
ToppCelldroplet-Marrow-BM-30m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 ADORA2B MET FCGRT VWA5A ST8SIA4 IL3RA

3.29e-061861507bcb3ac9f9b51346e0a2b0bda96d149b3c11f7883
ToppCell10x3'2.3-week_12-13-Myeloid_monocytic-monocyte-CD14_monocyte|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CES1 PABPC1 CCR2 FCGRT SLC2A6 LTB4R HCK

5.31e-0620015074984d27b3768be3b8fca3391cd2b7ab1749e2913
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages-T-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CIC CD4 RHPN2 PTPRZ1 AK2 CHPF2

6.83e-061361506186be8e1595608004b8216892cb9c7a7f31fbb4d
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BDH1 ABCB1 CCR2 MET LTB4R PIGO

1.29e-05152150687a7116d0064a6051bdf28ce1e48bfc168273e66
ToppCell367C-Fibroblasts-Fibroblast-G|367C / Donor, Lineage, Cell class and subclass (all cells)

COL6A3 PCBP3 CES1 CMYA5 SLC8A2 HSD17B2

2.27e-0516815068c95093b1ea45826f62893edd3c410fe53b563a4
ToppCell367C-Fibroblasts-Fibroblast-G-|367C / Donor, Lineage, Cell class and subclass (all cells)

COL6A3 PCBP3 CES1 CMYA5 SLC8A2 HSD17B2

2.27e-051681506b8c65542a0701ae31f49d332d87a64578e24b4e3
ToppCellfacs-Marrow-T-cells-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 ADORA2B MET VWA5A ADPRHL1 IL6ST

2.43e-051701506a78d9789c3e7c84a36e1bd380192d7aba4a4d443
ToppCellfacs-Marrow-T-cells-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 ADORA2B MET VWA5A ADPRHL1 IL6ST

2.43e-051701506ff68600b945b3a5437b14e5411b3db800d0ccbe5
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PRR36 GRM4 SCGB3A1 SLCO4C1 PTPRZ1 A2ML1

2.68e-051731506d1e47c87bd4750801f3531f66a56c5dccb4ea64c
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CBX4 JADE1 SIL1 ABCB1 MSI2 ADK

2.95e-051761506606704098bfdf8bfef740a3544a372fae1e75969
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CBX4 JADE1 SIL1 ABCB1 MSI2 ADK

2.95e-051761506acb9e29773030f6452a069f8f7e53eab68ab7bd3
ToppCellfacs-Marrow-T-cells-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 ADORA2B MET CD4 SGPL1 ST8SIA4

3.45e-0518115067286700396676fdc41d9723979b8b408177aceb9
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ERCC3 NCKIPSD BDH1 SGPL1 TDP1 MGA

3.90e-0518515067925519b855f76444a0b57382ce35d89457b0b14
ToppCellfacs-Lung-18m-Epithelial-alveolar_epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCA3 ITIH1 ADORA2B MET SLC7A4 SLCO4C1

4.02e-051861506c7214e762b3b48197fdd0b36a50a4de2550a888f
ToppCelldroplet-Marrow-BM-1m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 ADORA2B MET FCGRT VWA5A IL3RA

4.14e-051871506028e7d6e1211e123879d2f353dc32fae1185dd8e
ToppCellfacs-Lung-18m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA4F ABCA3 ITIH1 ADORA2B SLC7A4 SLCO4C1

4.14e-051871506a5318c888b334e8695f38971a7d100b93cdaf04b
ToppCellfacs-Heart-Unknown-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLAAT1 PABPC4 CMYA5 RYR2 ADPRHL1 MYBPC3

4.14e-0518715060ffb988e0da2c7205c3515eca8e9851739bff5c5
ToppCellfacs-Heart-Unknown|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLAAT1 PABPC4 CMYA5 RYR2 ADPRHL1 MYBPC3

4.14e-051871506362e56426a568423a81e8a30e3ecf99b76135843
ToppCellfacs-Lung-18m-Epithelial-alveolar_epithelial-type_II_pneumocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA4F ABCA3 ITIH1 ADORA2B SLC7A4 SLCO4C1

4.14e-05187150664ba0df991eab8b2632751805d758c5f2711f4d7
ToppCellfacs-Heart-Unknown-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLAAT1 PABPC4 CMYA5 RYR2 ADPRHL1 MYBPC3

4.14e-051871506c004567767b89f3d89f5c7b28d952f3445957e1e
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

ABHD2 CMYA5 RYR2 PGM5 ADPRHL1 MYBPC3

4.27e-0518815066d249fe92d51a19da19ec14bb2262d394255d577
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4F ABCA3 AHCYL2 ADORA2B MET SLCO4C1

4.27e-051881506b1049003ca79c340bb8c78da66bdc0956e1aebc2
ToppCellfacs-Lung-EPCAM-3m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4F ABCA3 AHCYL2 ADORA2B MET SLCO4C1

4.27e-0518815063dd571bd8e7358b4346dea71f6bf9602dabf583c
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BCKDHB BDH1 CLCNKA CLCNKB SV2A KCNJ10

4.27e-05188150614e120b20e76baa07b6510a94f0c2dcdfdd52357
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BCKDHB BDH1 CLCNKA CLCNKB SV2A KCNJ10

4.40e-051891506443359d90fafae0c1de6bdcce9e8c95df6ea4de8
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BCKDHB CLCNKA CLCNKB SV2A KCNJ10 KNG1

4.53e-05190150668ba1934b2b3f0cec8efd229fe1db6e8be8a26b0
ToppCelldroplet-Marrow-nan-21m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 ADORA2B MET FCGRT VWA5A IL3RA

4.53e-0519015066c6d3259e23ec90c08756f500ae8a7aff8b8a5b3
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RBMS1 GRM4 MET PTPRZ1 ST8SIA4 RAB3B

4.53e-0519015061bbbf0ce222e51f9fd2daca0c18d3965fd4efd31
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BCKDHB CLCNKA CLCNKB SV2A KCNJ10 KNG1

4.53e-051901506010d7d13a3c16e614c36720ef690a505b9f3f7aa
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA4F ABCA3 AHCYL2 ADORA2B MET SLCO4C1

4.66e-051911506f98fc372e579ce69409afbbe0f83c03c7ea62632
ToppCellfacs-Heart-LV-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLAAT1 CMYA5 BDH1 RYR2 ADPRHL1 MYBPC3

4.66e-051911506543da1197c7e62f2c9cbd4a51414bbaaa6d1a92f
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

ABHD2 CMYA5 RYR2 PGM5 ADPRHL1 MYBPC3

4.66e-0519115065d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA4F ABCA3 AHCYL2 ADORA2B MET SLCO4C1

4.66e-051911506210589095a3f5d5117174caf6ec110b502f27030
ToppCellfacs-Heart-LV-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLAAT1 CMYA5 BDH1 RYR2 ADPRHL1 MYBPC3

4.66e-0519115069d7d680da3979e256191b534ebd14c5383e0cf93
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA4F ABCA3 AHCYL2 ADORA2B MET SLCO4C1

4.80e-0519215064a46f7980ec145be5b4bf8b98265e3e0f2ea4c63
ToppCellCOVID_vent-Myeloid-Monocytic-CD16+_Monocyte|COVID_vent / Disease condition, Lineage, Cell class and subclass

PLAAT1 CD4 FCGRT SLC2A6 IL3RA HCK

5.08e-051941506b133d3d198360269cc449a75d34c29be377d91e0
ToppCellRA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

ABHD2 CMYA5 RYR2 PGM5 ADPRHL1 MYBPC3

5.08e-05194150689812fb164065041357bb37a3c2d87028ec3de4e
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

ABHD2 CMYA5 RYR2 PGM5 ADPRHL1 MYBPC3

5.08e-051941506c3535f7cc0076653c72db582047cff053c322397
ToppCellsevere_COVID-19-Non-classical_Monocyte|severe_COVID-19 / disease group, cell group and cell class (v2)

SCGB3A1 CD4 FCGRT SLC2A6 IL3RA HCK

5.38e-05196150634c1c74cad5e23196e86cfd6f19c836fe57b2264
ToppCellLV-03._Atrial_Cardiomyocyte|LV / Chamber and Cluster_Paper

CBX4 CMYA5 RYR2 TIA1 MYBPC3

5.39e-0512015053b77bd0e3630cdd45001cecf5e47660a90ebc92e
ToppCellHealthy/Control-Non-classical_Monocyte|World / Disease group and Cell class

SCGB3A1 CD4 FCGRT SLC2A6 IL3RA HCK

5.53e-051971506470784932e1fc3ff69f27cd83f56d85b0c01af63
ToppCellBronchus_Control_(B.)-Epithelial-TX-AT1|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

WNT3 TECTA CLCNKA CLCNKB KCNH1 UBR3

5.53e-051971506f7ef62d78336812573148f8bfce401877ec4e29c
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA3 RYR2 PGM5 LHCGR SLC8A3 ADPRHL1

5.69e-0519815061e1ea54f0c234f3b6d29064c4881d8a0c0949a75
ToppCellHealthy_donor-Non-classical_Monocyte|World / disease group, cell group and cell class (v2)

SCGB3A1 CD4 FCGRT SLC2A6 IL3RA HCK

5.69e-0519815068a97c8b2a43e6d1e669ce18752841e2006744bd9
ToppCellbackground|World / Sample and Cell Type and Tumor Cluster (all cells)

CES1 ITIH1 ADH4 CD4 CSMD1 KNG1

5.85e-0519915065a6d0e00bfe1351eea192b54020bedeef78854e9
ToppCellcontrol-Epithelial-Secretory|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PABPC4 CMYA5 RIF1 SLCO4C1 PTPRZ1 IL6ST

5.85e-0519915063d01f90ffd271ca00129192787e4921bdca7e01e
ToppCellcontrol-Epithelial-Secretory|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PABPC4 CMYA5 RIF1 SLCO4C1 PTPRZ1 IL6ST

5.85e-051991506262e5b8a52c8ddb0b47048c786e8bdb7158e1b9a
ToppCelldroplet-Heart-HEART-1m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABHD2 LHPP HEATR1 ABCB4 SLC2A6

7.06e-051271505983489a69d3b1f1fe21110a862ac1dba53e9d31c
ToppCellLV-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

CBX4 CMYA5 RYR2 TIA1 MYBPC3

7.89e-051301505a3e12984fb61311e49cc76c59f74f4dffc48faa1
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TASP1 PABPC1 CCR2 ABCB9 LTB4R

1.12e-04140150511e441c3435ad8911ab401ca7d4ae1d3e5fa6eac
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TASP1 PABPC1 CCR2 ABCB9 LTB4R

1.12e-04140150594444b92acfad64d811ebb1545dc1dab64473795
ToppCellImmune_cells-Monocytes|World / Lineage and Cell class

CCR2 ADORA2B SLC2A6 LTB4R HCK

1.45e-041481505e8037e831a6b11b06073b4e76684eb61308822f1
ToppCellfacs-Lung-3m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTBP2 GRM8 CD4 DBX1 PIGO

1.50e-041491505efa30fcd9370f98eb7445f295eb4d0305ff455c3
ToppCellE16.5-Immune-Immune_Myeloid-Granulocytic|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCB4 CCR2 ADORA2B SLC2A6 LTB4R

1.80e-041551505c648512305166d2a2f0e284c127bc802af908071
ToppCellControl-Epithelial-Ionocyte|Epithelial / Disease state, Lineage and Cell class

PCBP3 SLC7A4 CLCNKA CLCNKB KCNH1

1.80e-0415515054b9369b203a4d7071c56d3d8e6b450e9a0121c41
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

HIPK4 ABCB4 SLC8A2 PABPC3 ST8SIA4

1.91e-0415715057ceae5fe00c91d4feb8c314d3a31f027c03fa56f
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 ADORA2B SLC2A6 LTB4R HCK

1.97e-041581505bd37d567754b660bfff7aef81cb307a384ec20a0
ToppCellfacs-Lung-3m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GRM8 BDH1 CD4 ABCB9 DBX1

2.03e-0415915054750ba9ca06ed97b18df3c74eeb51d3ac8763f63
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TASP1 AHCYL2 PABPC1 CCR2 LTB4R

2.03e-0415915055c7a099aa84ecc62bf9b5e1609e5b6b77889f175
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MET SCGB3A1 RHPN2 PTPRZ1 HSD17B2

2.15e-0416115052d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

LHFPL4 CES1 ABCB1 SLCO4C1 RTP5

2.15e-041611505bf4bfb416cb6ef43fc8cf0ffc2d7f0b6b42ab4da
ToppCellControl-Epithelial-Ionocyte|World / Disease state, Lineage and Cell class

PCBP3 SLC7A4 CLCNKA CLCNKB KCNH1

2.21e-041621505e3b9b46ce2faff7d099502df14bbf51e9f183f8c
ToppCellControl-APC-like-Monocytes|Control / group, cell type (main and fine annotations)

SLC2A8 DDX60 RAB3D HCK MYBPC3

2.27e-0416315054bc80a2c741d462724b6f3902377d48c57478932
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|E18.5-samps / Age Group, Lineage, Cell class and subclass

COL6A3 LHFPL4 BCKDHB ABCB9 KCNJ10

2.34e-041641505519ab4fe885dfe4c50846f346a062acc2cb44299
ToppCelldroplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABHD2 CCR2 PARP9 LTB4R HCK

2.41e-041651505354978d4f35154d7b2e36e94de669e045adef512
ToppCellfacs-Heart-LA-24m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMYA5 RYR2 CLCNKA ADPRHL1 MYBPC3

2.47e-041661505829a8998ce68739a58202851afd73e049ab0f84f
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-Lymphoid_DC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITIH1 DPP9 SLC2A6 HCK MYBPC3

2.47e-04166150575d719617c61409860f298ce91cbe3a0aafa0553
ToppCellfacs-Heart-LA-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMYA5 RYR2 CLCNKA ADPRHL1 MYBPC3

2.47e-041661505c43aec09578975df8984886993d15b42a10190c8
ToppCelldroplet-Bladder-nan-3m-Hematologic-granulocyte-monocyte_progenitor|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 SLC2A6 LTB4R ST8SIA4 HCK

2.47e-041661505e01c720de6d4ca144c55378e023e718a64bf32f6
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

LHFPL4 PRR36 SV2B SV2A RAB3B

2.54e-041671505c87ebfa8c3284ad33579190e148c95bcaf670d17
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A8 BDH1 SLCO4C1 ENTPD5 HSD17B2

2.62e-04168150535ce3b2b9c9997d4c101da5949c7271d6a6b8f12
ToppCellCOVID-19-Heart-CM_+_Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

CMYA5 RYR2 PGM5 ADPRHL1 MYBPC3

2.76e-0417015053f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

CMYA5 RYR2 CD4 HCK MYBPC3

2.76e-0417015054232fe937909f93d3736988c707b8f95ce993398
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLAAT1 LHFPL4 ADPRHL1 CDON MYBPC3

2.84e-04171150582de2885c8ce4fb7776da6a0207b3355c0910121
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLAAT1 LHFPL4 ADPRHL1 CDON MYBPC3

2.84e-04171150509e653973962fb884878089d281f0947f7a285f6
ToppCellnormal_Lung-T/NK_cells-CD8+/CD4+_Mixed_Th|T/NK_cells / Location, Cell class and cell subclass

COL6A3 VWA5A RAB3A HCK RSKR

2.91e-0417215050657c736f3c52d25cf7f652eac005ddcde9232ef
ToppCellfacs-Heart-Unknown-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLAAT1 CMYA5 RYR2 ADPRHL1 MYBPC3

2.91e-041721505ee8ce9e8c9a6d3ee2be113f77743958005f4b3f0
ToppCell343B-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CBX4 CMYA5 MET PABPC3 PABPC1L

2.91e-041721505c6bc78fd63c9479a84ec0552b55c89750cad0fa5
ToppCellInt-URO-Lymphocyte-T_NK-dnT|Int-URO / Disease, Lineage and Cell Type

SLC25A14 TASP1 BCKDHB BDH1 PUS10

2.91e-041721505e70299573da1679d6d286c3a43699cbff76e207d
ToppCell343B-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CBX4 CMYA5 MET PABPC3 PABPC1L

2.91e-041721505bfb87a281a9cf6ad45b310bf8104fc0ab382b549
ToppCellfacs-Marrow-B-cells-24m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIL1 PGM5 RHPN2 RAB3A RAB3B

2.91e-04172150565b8935a972bf00b7a10dc2d442128fc0ed78bcb
ToppCellfacs-Heart-Unknown-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLAAT1 CMYA5 RYR2 ADPRHL1 MYBPC3

2.91e-041721505bd468a7ea6ec832dcf6a816a1e0c03fa0f176dad
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX60 PABPC1 ABCB4 UBE2B HSD17B2

2.91e-0417215054790323a072cfe76127d704665a42c09601d84be
ToppCellTCGA-Brain-Primary_Tumor|TCGA-Brain / Sample_Type by Project: Shred V9

AHCYL2 ABCB1 PTPRZ1 KCNJ10 A2ML1

2.99e-041731505f6ba22661e67c17d49d1058d4170ba8f36bf47f0
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-pDC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TNK1 PRR36 CCR2 SLC2A6 IL3RA

3.07e-0417415054120656e6d6cf5435a248326b5fdbdc7b22137af
ToppCellAdult-Epithelial-lung_goblet_cell-D231|Adult / Lineage, Cell type, age group and donor

MET SCGB3A1 PTPRZ1 HSD17B2 CDON

3.07e-0417415057d2f802f493f19a068e097b2909a9000e2160266
ToppCellCOVID-19-kidney-PCT-S3-2|kidney / Disease (COVID-19 only), tissue and cell type

CES1 ITIH1 ABCB4 ADH4 KNG1

3.07e-0417415055aa2fb631505600f37d2b87b02def7be139dc262
ToppCell3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRR36 CES1 ADORA2B RAB3B CDON

3.07e-041741505a62531ebf16b32b249168dca11b870f63a8aa81c
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 ADORA2B SLC2A6 LTB4R HCK

3.16e-0417515053bca1aac2a2a1f46753b5f9462888f144ed8327b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic-Neutrophil|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RAB3D TECTA ST8SIA4 DDX41 MYBPC3

3.24e-041761505676839d07450b313222622e0ffd305c732cbad6d
ToppCellfacs-MAT-Fat-3m-Lymphocytic-T_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TASP1 AHCYL2 CCR2 ABCB9 LTB4R

3.24e-04176150571b3309ddadd035a1224fca4fc5946dc4c0283fe
ToppCellCOVID-19-Heart-CM_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

CMYA5 RYR2 PGM5 ADPRHL1 MYBPC3

3.24e-0417615059df7a124ebafb0087da0cda133a394275d7bed81
DrugKS24

PABPC1 TIA1 PABPC3

5.41e-0661493CID000099135
DrugPF-01378883-00 [351320-41-7]; Down 200; 10uM; PC3; HT_HG-U133A

SEMA4F PRR36 RAB3D U2AF2 BCKDHB MET UBE2B CD4 VWA5A

6.75e-0619914996368_DN
Drugadenine

IMPA1 TRMT1 AHCYL2 PABPC1 NFU1 RYR2 SIL1 ADK ADORA2B IGF2R FCGRT PABPC3 AK2 MOCS1

6.88e-0651014914CID000000190
Diseaseage at menarche, spine bone mineral density

ABCB1 SLC25A40 KCNH1

1.42e-05101473EFO_0004703, EFO_0007701
Diseasetemporal lobe epilepsy (biomarker_via_orthology)

ABCB1 ADK PTPRZ1 AK2

1.68e-05311474DOID:3328 (biomarker_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

RAB3D GRM8 ABCB1 KCNH1 SV2A RAB3A RAB3B

1.84e-051631477DOID:1826 (implicated_via_orthology)
DiseaseBartter disease type 4B

CLCNKA CLCNKB

2.47e-0521472cv:C4310805
Diseasecollagen alpha-3(VI) chain measurement

COL6A3 COPS8

2.47e-0521472EFO_0802421
DiseaseBartter disease type 3 (implicated_via_orthology)

CLCNKA CLCNKB

2.47e-0521472DOID:0110144 (implicated_via_orthology)
DiseaseBARTTER SYNDROME, TYPE 4B, NEONATAL, WITH SENSORINEURAL DEAFNESS

CLCNKA CLCNKB

2.47e-0521472613090
DiseaseBARTTER SYNDROME, TYPE 4B

CLCNKA CLCNKB

2.47e-0521472C2751312
DiseaseBARTTER SYNDROME, TYPE 4B, NEONATAL, WITH SENSORINEURAL DEAFNESS

CLCNKA CLCNKB

2.47e-0521472C4310805
DiseaseBartter disease type 4b (is_implicated_in)

CLCNKA CLCNKB

2.47e-0521472DOID:0110146 (is_implicated_in)
DiseaseBartter disease (implicated_via_orthology)

CLCNKA CLCNKB

2.47e-0521472DOID:445 (implicated_via_orthology)
Diseaseamyotrophic lateral sclerosis (biomarker_via_orthology)

IGF2R PTPRZ1 KCNJ10

3.34e-05131473DOID:332 (biomarker_via_orthology)
Diseaseanaphylaxis

LTB4R KNG1

1.47e-0441472C0002792
Diseaseresponse to carbamazepine

COL6A3 COPS8

1.47e-0441472EFO_0008484
Diseasestatus epilepticus (biomarker_via_orthology)

ABCB1 SLC8A2 SLC8A3 PTPRZ1 IL6ST

1.48e-041001475DOID:1824 (biomarker_via_orthology)
Diseasebrain ischemia (biomarker_via_orthology)

AQP8 ABCB1 SLC8A2 SLC8A3 IL6ST

1.62e-041021475DOID:2316 (biomarker_via_orthology)
DiseaseBartter syndrome

CLCNKA CLCNKB

3.65e-0461472cv:C0004775
Diseasebipolar disorder, schizophrenia, schizoaffective disorder

ITIH1 CSMD1

3.65e-0461472EFO_0005411, MONDO_0004985, MONDO_0005090
DiseaseIschemic stroke, factor VII measurement

HECTD4 PIGU ADH4

4.03e-04291473EFO_0004619, HP_0002140
Diseaseaspartate aminotransferase measurement

WNT3 HECTD4 PIGU ITIH1 ABCB1 ABCB4 ADH4 FCGRT ZPR1 ENTPD5 CSMD1 CLEC16A MYBPC3

6.14e-0490414713EFO_0004736
Diseasebody shape measurement

HSP90B2P GRM8

6.77e-0481472EFO_0801227
DiseaseCOVID-19 symptoms measurement

WNT3 CCR2 DPP9

7.05e-04351473EFO_0600019
DiseaseHEPATOCELLULAR CARCINOMA

MET IGF2R

8.67e-0491472114550
Diseasegallbladder neoplasm

ABCB1 ABCB4

8.67e-0491472EFO_0004606
Diseasecystic fibrosis (implicated_via_orthology)

ABCB1 ABCB4

8.67e-0491472DOID:1485 (implicated_via_orthology)
Diseasemitochondrial ubiquitin ligase activator of NFKB 1 measurement

RPSA KNG1

8.67e-0491472EFO_0801804
DiseaseHepatocellular carcinoma

MET IGF2R

8.67e-0491472cv:C2239176
Diseasefeeling nervous measurement

PIGU ITIH1 CSMD1 MGA

9.55e-04871474EFO_0009597
Diseasenephrogenic diabetes insipidus (implicated_via_orthology)

CLCNKA CLCNKB

1.08e-03101472DOID:12387 (implicated_via_orthology)
Diseasetriacylglycerol 54:1 measurement

IGF2R ZPR1

1.08e-03101472EFO_0010419
Diseaseunipolar depression, anorexia nervosa

PTBP2 NCKIPSD

1.08e-03101472EFO_0003761, MONDO_0005351
Diseaseapolipoprotein A 1 measurement

CES1 PABPC4 PIGU ITIH1 ADH4 LHCGR ABCB9 ZPR1 DLEC1 MGA CNOT1 MYBPC3

1.14e-0384814712EFO_0004614
Diseasepulse pressure measurement

COL6A3 PCBP3 PCDHAC1 HEATR5A SLC25A26 GRM4 ITIH1 MSI2 MET COPS8 UBR3 DLEC1 CLEC16A CNOT1 RSKR MYBPC3

1.61e-03139214716EFO_0005763
DiseaseOsteosarcoma

GRM4 MET KCNH1

1.67e-03471473C0029463
DiseaseQRS-T angle

SLC25A26 RYR2 ADPRHL1 MYBPC3

1.98e-031061474EFO_0020097
DiseaseHamman-Rich syndrome

ABCA3 DPP9

2.16e-03141472C0085786
Diseaseearly cardiac repolarization measurement

SLC9A8 RAB3D

2.16e-03141472EFO_0004885
Diseasehepatocellular carcinoma (is_implicated_in)

CBX4 ABCB1 EFTUD2 MET IGF2R

2.18e-031811475DOID:684 (is_implicated_in)
DiseaseMalignant mesothelioma

SEMA4F WNT3 RYR2 MET

2.19e-031091474C0345967
Diseasecholesterol to total lipids in large LDL percentage

PABPC4 ZPR1 MYBPC3

2.77e-03561473EFO_0022235
Diseasefactor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement

HECTD4 ADH4 KNG1

2.77e-03561473EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
Diseaseteratocarcinoma-derived growth factor 1 measurement

CCR2 SLC8A3

2.83e-03161472EFO_0008297
DiseaseIntrahepatic cholestasis of pregnancy

ABCB1 ABCB4

2.83e-03161472EFO_0009048
DiseaseMalignant neoplasm of breast

ABCA3 ERCC3 RPS6KB2 AQP8 TECTA PABPC1 CIC ABCB1 LHCGR RIF1 SLC8A3 KCNH1 DLEC1

2.85e-03107414713C0006142
Diseasefibrinogen measurement, factor VII measurement

HECTD4 PIGU ADH4

3.06e-03581473EFO_0004619, EFO_0004623
DiseaseInborn Errors of Metabolism

CES1 AGXT2

3.19e-03171472C0025521
Diseaseresponse to radiation, Urinary retention

COL6A3 COPS8

3.19e-03171472GO_0009314, HP_0000016
Diseasetriacylglycerol 48:1 measurement

ZPR1 CSMD1

3.19e-03171472EFO_0010404
Diseasefactor XI measurement, Ischemic stroke

HECTD4 KNG1

3.19e-03171472EFO_0004694, HP_0002140
DiseaseFEV/FEC ratio

COL6A3 ABCA3 BLOC1S4 RBMS1 PABPC4 TASP1 ADK MET COPS8 DLEC1 CSMD1 MGA CLEC16A CDON

3.38e-03122814714EFO_0004713
DiseaseTachycardia

RYR2 KNG1

3.58e-03181472C0039231
DiseaseTachyarrhythmia

RYR2 KNG1

3.58e-03181472C0080203
Diseaselysophosphatidylcholine measurement

COL6A3 ZPR1 MGA

3.70e-03621473EFO_0010224
DiseaseAllergic Reaction

CCR2 KNG1 IL6ST

3.87e-03631473C1527304
DiseaseLiver carcinoma

MED1 ABCB1 ABCB4 ADH4 MET IGF2R CSMD1 SLC26A6

4.01e-035071478C2239176
DiseaseHypersensitivity

CCR2 KNG1 IL6ST

4.04e-03641473C0020517
Diseasehepatocellular carcinoma (is_marker_for)

CES1 CBX4 EFTUD2 MET IGF2R KCNH1

4.08e-033011476DOID:684 (is_marker_for)
DiseaseCOVID-19, osteoarthritis

CCR2 DPP9

4.42e-03201472MONDO_0005178, MONDO_0100096
Diseasesphingomyelin 22:0 measurement

HEATR1 CSMD1

4.42e-03201472EFO_0010395
DiseaseSchizophrenia

CMYA5 GRM4 GRM8 ITIH1 ABCB1 ADK MET PTPRZ1 SV2A CSMD1 IL3RA

4.81e-0388314711C0036341
Diseaseserum IgG glycosylation measurement

BLOC1S4 RPSA RYR2 SLC8A3 ABCB9 CHPF2 CSMD1 ST8SIA4

4.82e-035231478EFO_0005193
DiseaseIdiopathic Pulmonary Fibrosis

ABCA3 DPP9

4.86e-03211472C1800706

Protein segments in the cluster

PeptideGeneStartEntry
SVAKSIAGFFAEPIQ

AGXT2

276

Q9BYV1
KFVSLEGFAQPVAIF

CES1

36

P23141
ELFSVFGAPFLKEGA

CES1

471

P23141
FKPGTFDGCISISAV

BUD23

111

O43709
IFFGADNAIPKSETT

CABS1

26

Q96KC9
GFFLTVSPESVLKVA

ADK

186

P55263
EVFFQCKSPFILVGS

CSMD1

3176

Q96PZ7
VTKAEAELGTFPRAF

BLOC1S4

156

Q9NUP1
YASAAEPVGSKAVLV

BDH1

46

Q02338
AADVAVGLFAIPFAI

ADORA2B

51

P29275
ATVIDSKFEGLAFPV

ADH4

51

P08319
PAVFDGVKLAAVAAV

ABHD2

11

P08910
FIPIFFGTSQSADKL

GRM4

801

Q14833
TVGLTAFKPFFVDLT

A2ML1

781

A8K2U0
EFKAFVDLTFPGSVL

ABCA3

1626

Q99758
APFSIGFAVTVDILA

AQP8

186

O94778
AVAKEVAGPAVLLSF

SLC7A4

61

O43246
FLPFGAVVSAKVFVD

CELF6

416

Q96J87
KIAAFFAESLPSVGG

PHYKPL

206

Q8IUZ5
FVTFADPASVDKVLG

MSI2

66

Q96DH6
GFVDFDSPAAAQKAV

RBMS1

106

P29558
SFTPAFVSTVGIDFK

RAB3A

46

P20336
TFTPAFVSTVGIDFK

RAB3B

46

P20337
SFTPAFVSTVGIDFK

RAB3D

46

O95716
IAGIVLDVGSKVSFF

CRYZL1

66

O95825
CKGFFVAVPVAVTFL

IMMP2L

16

Q96T52
EDPTVAAFKAASEFI

PARP9

281

Q8IXQ6
GFVCFSSPEEATKAV

PABPC1

336

P11940
PAFAIIFSKIIGVFT

ABCB1

726

P08183
GFFVSPSDSLAIIAA

PGM5

306

Q15124
GKFVSLEGFAQPVAV

CES1P1

36

Q9UKY3
AKDPTAVIFGEDVAF

BCKDHB

86

P21953
GFVCFSSPEEATKAV

PABPC4

336

Q13310
GEVTFKSILFVPTFV

HSP90B2P

36

Q58FF3
EVFDSVKPGLSAFVD

ENTPD5

81

O75356
SFFAISAAFKVPLIT

LHCGR

586

P22888
GIKLPSSVFASEFEE

LTV1

106

Q96GA3
DFSLFDQVVKVASPS

KCNJ10

326

P78508
SVFFGPDFITVTKEN

NFU1

111

Q9UMS0
TVAGAAPTFFVILKQ

MGA

16

Q8IWI9
IPKTAFISDFAVTAD

ITIH1

91

P19827
PFRVKVIDFGSASIF

HIPK4

151

Q8NE63
PDVVFASILAAFSKA

AK2

216

P54819
LGFIPTSSFVVDKFA

DDX60

456

Q8IY21
TSVPTAKFALNGEEF

FCGRT

126

P55899
PASETTFLKFGVNAI

DBX1

101

A6NMT0
FGNIAPSTDIEKIFA

KCNH1

466

O95259
VLLFSLATGKFPVAA

RSKR

291

Q96LW2
SPEFFKSALQAIGVE

LHPP

191

Q9H008
GKVFAGIPTVASDTF

PTPRZ1

1346

P23471
GFVCFSSPEEATKAV

PABPC1L

336

Q4VXU2
LVATDVASKGLDFPA

DDX41

486

Q9UJV9
NFPGAAFVVVSCKES

HECTD4

2586

Q9Y4D8
FVLTKSFLPVVSTFG

SLC2A6

446

Q9UGQ3
AFIPIFFGTAQSAEK

GRM8

796

O00222
TIPSSAFKAAAFFVL

LHFPL4

86

Q7Z7J7
AVIAIFKSYPTVGDV

PIGU

321

Q9H490
AVTGFLLPFLAVVAS

LTB4R

186

Q15722
KFSPESVAAFIAVLG

MFSD14A

276

Q96MC6
AVASAVVLLGPVAFK

MOCS1

506

Q9NZB8
GFVCFSSPEEATKAV

PABPC3

336

Q9H361
VTITGPTDAIFKAFA

PCBP3

91

P57721
PAFSVIFSEIIAIFG

ABCB4

726

P21439
EDAAPGTVIALFSVK

PCDHAC1

351

Q9H158
PIDGKSLFEVSVVFA

PUS10

201

Q3MIT2
VFLLGFIPAKADSVV

UPF1

191

Q92900
PEAINFGSFTIKSDV

HCK

426

P08631
FGIPCTDKFVVFSQI

IL3RA

191

P26951
FTFTTPKFAQGEIEA

IL6ST

606

P40189
PEAVTGFSFAVAALL

HEATR5A

496

Q86XA9
PKSAGVATFVIQEEF

DPP9

236

Q86TI2
FQPFTFSLKGLSEEV

CMYA5

1741

Q8N3K9
PVSAKVADGDFVTLS

CDON

411

Q4KMG0
SIGFTLADKVDGPFF

NDUFAF1

281

Q9Y375
AVELKQFGVAPFTIA

COL6A3

1356

P12111
ASVEVKATFGPAIAA

DDX11L8

881

A8MPP1
SEFKPFFGNIIITDV

CBX4

531

O00257
FSFPLAFTVEKLTGS

CD4

221

P01730
TALFVSFAAQGKPLV

ADPRHL1

176

Q8NDY3
LVAVFASVPGIIFTK

CCR2

166

P41597
PVFSTFVLTGAAGDK

DENND4B

256

O75064
LAKPGVTVTFSDFQD

KNG1

551

P01042
TSIIADDFAAFVGLP

COPS8

126

Q99627
FTLFAGHLVKPFADT

HEATR1

1951

Q9H583
FPQTALVSFATTGEK

EMC1

316

Q8N766
FISKVGDTSFDLPEA

ERCC3

606

P19447
LSFKAIATVGFVEQP

DLEC1

521

Q9Y238
VNFFGTVEVTKTFLP

HSD17B2

191

P37059
GFAAAVTTPLDVAKT

SLC25A26

191

Q70HW3
GLFFPVVSFSAGIKV

RYR2

786

Q92736
VGLVVFFTTFLTPAA

COX8C

46

Q7Z4L0
FSIISVAGKALAPAD

MED1

931

Q15648
AAPFIFTSGEVVNLA

GABPB2

181

Q8TAK5
ILFGVFAQSKPDSAE

MET

341

P08581
PLSAKGTADAFIVRF

IGF2R

1026

P11717
AVLKFAAATGATPIA

RPSA

86

P08865
ASITFPFIFTDVKDA

RTP5

366

Q14D33
TVTEGAAKIAFPSAN

TRMT1

56

Q9NXH9
ILAFVGAAVAVPFDD

PRSS3P2

6

Q8NHM4
EVAAALAESGFPVFA

AHCYL2

266

Q96HN2
PSADTTILFVKGEDF

SSR1

81

P43307
GTFAFDPKCGVIDVS

SEMA4F

141

O95754
AAAFAKETSLLAVPG

PTBP2

291

Q9UKA9
ADGVEVFVVSFALPS

SV2B

121

Q7L1I2
GSFAAVATLPFDVVK

SLC25A40

246

Q8TBP6
APSVLDSIKEGFSFQ

RPS6KB2

391

Q9UBS0
FVSSKADLPEGVAVS

RHOT2

521

Q8IXI1
FVAVGKDAPDVVVSA

RIF1

486

Q5UIP0
FSKLVGSAFTIAVVG

SLC26A6

341

Q9BXS9
RFPFVAVSIGFAVNK

IMPA1

101

P29218
PFVAGFAVITAAQDV

SLC2A8

106

Q9NY64
FPEAGVSSLATAAFV

PRR36

406

Q9H6K5
EKPFSSVAAKAIGVA

KCNV2

251

Q8TDN2
LAPVVEFAADVGTKS

ST8SIA4

171

Q92187
AAFVLGAAFSSNPKV

SIL1

246

Q9H173
FAFGSLISAVDPVAT

SLC9A8

191

Q9Y2E8
VPESFLGLEKTFAEA

JADE1

626

Q6IE81
TVTDFFQKLGPLSVF

RHPN2

491

Q8IUC4
KFLQDVFGSPATAAI

NCKIPSD

616

Q9NZQ3
ISIFTSFVGITKAAP

SV2A

701

Q7L0J3
SFVGITKAAPILFAS

SV2A

706

Q7L0J3
PFDFRVKGVTSISAD

SGPL1

336

O95470
TKPDVAFLVAASFFL

ABCB9

181

Q9NP78
KAAIASIPVGSFEAG

CIC

1181

Q96RK0
PEKEGSSAFLSAFAV

CHPF2

291

Q9P2E5
SVFASVDKVPGFAVA

CLEC16A

871

Q2KHT3
AVGVATVFAAPFSGV

CLCNKA

206

P51800
TVFAAPFSGVLFSIE

CLCNKA

211

P51800
AVGVATVFAAPFSGV

CLCNKB

206

P51801
TVFAAPFSGVLFSIE

CLCNKB

211

P51801
GTPFAFVIDLAALAS

CNOT1

576

A5YKK6
SSEIKLAIPVFFFGV

TECTA

46

O75443
SIVAEFGTFPVDLTK

SLC25A14

51

O95258
VLFLPSAFGLDSFKV

TDP1

541

Q9NUW8
DFEIPAFSQKGALTT

ZPR1

131

O75312
FPGCEKTFITVSALF

ZXDC

301

Q2QGD7
ADAFFKAAISLVPEV

VPS35L

741

Q7Z3J2
LITTGFATFLPKFIE

SLCO4C1

396

Q6ZQN7
FGPVLDKATRESAFV

WNT3

101

P56703
AITFLKSSVDPAIFA

VWA5A

771

O00534
GFTFSVPVAKTAELS

NUP153

546

P49790
VDGIPASFTSAKSVF

PLAAT1

46

Q9HDD0
FESVLSAVADFKAPV

UBR3

826

Q6ZT12
KVGSFPASAVTLADA

TNK1

431

Q13470
VPGCGKIFVEFTSVF

U2AF2

426

P26368
PKFIFEAVGFIVSSV

PIGO

1046

Q8TEQ8
IKAFIPAIDSFGFET

EFTUD2

871

Q15029
KFISSPFLASEDGVL

TASP1

326

Q9H6P5
SSAAAFLVGSAKPVA

SCGB3A1

16

Q96QR1
EITTEDIKAAFAPFG

TIA1

116

P31483
TPFEDGTFKLVIEFS

UBE2B

46

P63146
TIAFIAFSTNPELAK

LIPK

176

Q5VXJ0
VVFVALGTSIPDTFA

SLC8A2

786

Q9UPR5
AVVFVAFGTSVPDTF

SLC8A3

791

P57103
GFSDRAATTKEPVFI

MYBPC3

1146

Q14896