Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF419 ZNF93 ZNF131 KLF12 ZNF676 ZNF320 ZBTB17 ZNF560 KLF10 ZNF473 ZNF423 ZNF587 ZNF846 ZNF66 ZNF621 ZNF772 ZNF723 REST ZNF90 ZNF763 ZNF626 ZNF417 ZNF840P PRDM2

2.91e-1114596824GO:0000977
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ZNF419 ZNF93 ZNF131 KLF12 ZNF676 ZNF320 ZBTB17 KLF10 ZNF473 ZNF423 ZNF587 ZNF66 ZNF621 ZNF772 ZNF723 REST ZNF90 ZNF763 ZNF626 ZNF417 ZNF840P TIPARP

9.57e-1112716822GO:0000987
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF419 ZNF93 ZNF131 KLF12 ZNF676 ZNF320 ZBTB17 ZNF560 KLF10 ZNF473 ZNF423 ZNF587 ZNF846 ZNF66 ZNF621 ZNF772 ZNF723 REST ZNF90 ZNF626 ZNF417 ZNF840P PRDM2

1.05e-1014126823GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF419 ZNF93 ZNF131 KLF12 ZNF676 ZNF320 ZBTB17 KLF10 ZNF473 ZNF423 ZNF587 ZNF66 ZNF621 ZNF772 ZNF723 REST ZNF90 ZNF763 ZNF626 ZNF417 ZNF840P

4.57e-1012446821GO:0000978
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity, RNA polymerase II-specific

ZNF93 ZNF131 KLF12 ZBTB17 REST PRDM2

7.68e-04320686GO:0001227
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity

ZNF93 ZNF131 KLF12 ZBTB17 REST PRDM2

8.46e-04326686GO:0001217
GeneOntologyMolecularFunctioncore promoter sequence-specific DNA binding

ZBTB17 KLF10 REST

8.73e-0455683GO:0001046
Domain-

ZNF419 ZNF93 ZNF131 KLF12 ZNF676 ZNF320 ZBTB17 ZNF560 KLF10 ZNF473 ZNF423 ZNF587 ZNF846 ZNF621 ZNF772 REST ZNF90 ZNF763 ZNF626 ZNF417 ZFPM2 PRDM2

4.30e-1667965223.30.160.60
Domainzf-C2H2

ZNF419 ZNF93 ZNF131 KLF12 ZNF676 ZNF320 ZBTB17 ZNF560 KLF10 ZNF473 ZNF423 ZNF587 ZNF846 ZNF621 ZNF772 REST ZNF90 ZNF763 ZNF626 ZNF417 ZFPM2 PRDM2

6.57e-166936522PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF419 ZNF93 ZNF131 KLF12 ZNF676 ZNF320 ZBTB17 ZNF560 KLF10 ZNF473 ZNF423 ZNF587 ZNF846 ZNF621 ZNF772 REST ZNF90 ZNF763 ZNF626 ZNF417 ZFPM2 PRDM2

6.77e-166946522IPR013087
DomainZINC_FINGER_C2H2_2

ZNF419 ZNF93 ZNF131 KLF12 ZNF676 ZNF320 ZBTB17 ZNF560 KLF10 ZNF473 ZNF423 ZNF587 ZNF846 ZNF621 ZNF772 REST ZNF90 ZNF763 ZNF626 ZNF417 ZFPM2 PRDM2

6.61e-157756522PS50157
DomainZINC_FINGER_C2H2_1

ZNF419 ZNF93 ZNF131 KLF12 ZNF676 ZNF320 ZBTB17 ZNF560 KLF10 ZNF473 ZNF423 ZNF587 ZNF846 ZNF621 ZNF772 REST ZNF90 ZNF763 ZNF626 ZNF417 ZFPM2 PRDM2

6.97e-157776522PS00028
DomainZnf_C2H2-like

ZNF419 ZNF93 ZNF131 KLF12 ZNF676 ZNF320 ZBTB17 ZNF560 KLF10 ZNF473 ZNF423 ZNF587 ZNF846 ZNF621 ZNF772 REST ZNF90 ZNF763 ZNF626 ZNF417 ZFPM2 PRDM2

1.14e-147966522IPR015880
DomainZnf_C2H2

ZNF419 ZNF93 ZNF131 KLF12 ZNF676 ZNF320 ZBTB17 ZNF560 KLF10 ZNF473 ZNF423 ZNF587 ZNF846 ZNF621 ZNF772 REST ZNF90 ZNF763 ZNF626 ZNF417 ZFPM2 PRDM2

1.44e-148056522IPR007087
DomainZnF_C2H2

ZNF419 ZNF93 ZNF131 KLF12 ZNF676 ZNF320 ZBTB17 ZNF560 KLF10 ZNF473 ZNF423 ZNF587 ZNF846 ZNF621 ZNF772 REST ZNF90 ZNF763 ZNF626 ZNF417 ZFPM2 PRDM2

1.55e-148086522SM00355
Domainzf-C2H2_6

ZNF419 ZNF93 ZNF676 ZNF320 ZNF560 ZNF473 ZNF423 ZNF587 ZNF846 ZNF621 ZNF90 ZNF763 ZNF626 ZNF417 PRDM2

1.69e-133146515PF13912
DomainKRAB

ZNF419 ZNF93 ZNF676 ZNF320 ZNF560 ZNF473 ZNF587 ZNF846 ZNF621 ZNF772 ZNF90 ZNF763 ZNF626 ZNF417

1.77e-113586514PS50805
DomainKRAB

ZNF419 ZNF93 ZNF676 ZNF320 ZNF560 ZNF473 ZNF587 ZNF846 ZNF621 ZNF772 ZNF90 ZNF763 ZNF626 ZNF417

2.65e-113696514SM00349
DomainKRAB

ZNF419 ZNF93 ZNF676 ZNF320 ZNF560 ZNF473 ZNF587 ZNF846 ZNF621 ZNF772 ZNF90 ZNF763 ZNF626 ZNF417

2.74e-113706514IPR001909
DomainKRAB

ZNF419 ZNF93 ZNF320 ZNF560 ZNF473 ZNF587 ZNF846 ZNF621 ZNF772 ZNF90 ZNF763 ZNF626 ZNF417

2.54e-103586513PF01352
DomainZF_DAG_PE_1

PRKCB UNC13C PLEKHM3 ARHGEF2

7.26e-0564654PS00479
DomainZF_DAG_PE_2

PRKCB UNC13C PLEKHM3 ARHGEF2

7.26e-0564654PS50081
DomainC1

PRKCB UNC13C PLEKHM3 ARHGEF2

7.71e-0565654SM00109
DomainPE/DAG-bd

PRKCB UNC13C PLEKHM3 ARHGEF2

8.19e-0566654IPR002219
DomainC1_1

PRKCB UNC13C ARHGEF2

1.03e-0357653PF00130
DomainC2H2_Znf_fam

ZNF131 REST

3.13e-0324652IPR027775
DomainBTB

ZNF131 KLHL24 ZBTB17

1.07e-02131653PF00651
Pubmed

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.

ZNF419 ZNF93 ZNF320 ZNF587 ZNF90 ZNF626 ZNF417

7.56e-0818169737372979
Pubmed

REST/NRSF-induced changes of ChAT protein expression in the neocortex and hippocampus of the 3xTg-AD mouse model for Alzheimer's disease.

CHAT REST

3.88e-06269225261598
Pubmed

Novel G protein-coupled receptors: a gene family of putative human olfactory receptor sequences.

OR1D5 OR1D2

3.88e-0626921315913
Pubmed

Sequence, structure, and evolution of a complete human olfactory receptor gene cluster.

OR1D5 OR1D4 OR1D2

4.11e-061669310673334
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZNF419 ZNF93 ZNF131 KLF12 ZBTB17 KLF10 ZNF473 ZNF423 REST ZNF626

4.28e-06808691020412781
Pubmed

Characterization and mapping of human genes encoding zinc finger proteins.

ZBTB17 ZNF66 ZNF763

1.12e-05226931946370
Pubmed

Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes.

ZBTB17 ZNF66 ZNF763

1.12e-05226931505991
Pubmed

Cholinergic Neurons of the Medial Septum Are Crucial for Sensorimotor Gating.

CHAT GRM5

2.32e-05469231028115
Pubmed

mGluR5-PLCbeta4-PKCbeta2/PKCgamma pathways in hippocampal CA1 pyramidal neurons in pilocarpine model of status epilepticus in mGluR5+/+ mice.

PRKCB GRM5

2.32e-05469218774262
Pubmed

mGluR5 regulates REST/NRSF signaling through N-cadherin/β-catenin complex in Huntington's disease.

REST GRM5

3.86e-05569232859226
Pubmed

SCFβ-TrCP-mediated degradation of TOP2β promotes cancer cell survival in response to chemotherapeutic drugs targeting topoisomerase II.

ATM TOP2B

5.79e-05669232015321
Pubmed

Shaking the family tree: identification of novel and biologically active alternatively spliced isoforms across the KLF family of transcription factors.

KLF12 KLF10

5.79e-05669223134681
Pubmed

Protein kinase C isoforms differentially phosphorylate human choline acetyltransferase regulating its catalytic activity.

PRKCB CHAT

8.09e-05769215381704
Pubmed

Systematic survey of deubiquitinase localization identifies USP21 as a regulator of centrosome- and microtubule-associated functions.

MAP4 ARHGEF2

1.08e-04869222298430
Pubmed

The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins.

ZNF93 ZNF90

1.08e-0486922023909
Pubmed

Protein-protein interaction of zinc finger LIM domains with protein kinase C.

PDLIM7 PRKCB

1.08e-0486928940095
Pubmed

Protein kinase C phosphorylation of the metabotropic glutamate receptor mGluR5 on Serine 839 regulates Ca2+ oscillations.

PRKCB GRM5

1.08e-04869215894802
Pubmed

Mouse-human orthology relationships in an olfactory receptor gene cluster.

OR1D5 OR1D2

1.08e-04869211170746
Pubmed

Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire.

OR1D4 OR1D2

2.11e-04116928004088
Pubmed

HIV-1 Tat and AIDS-associated cancer: targeting the cellular anti-cancer barrier?

PRKCB ATM

2.53e-041269218577246
Pubmed

BAG5 Promotes Alpha-Synuclein Oligomer Formation and Functionally Interacts With the Autophagy Adaptor Protein p62.

MAP4 PDLIM7 ANKRD28 ARHGEF2

2.68e-0415669432850835
Pubmed

Binary Fate Choice between Closely Related Interneuronal Types Is Determined by a Fezf1-Dependent Postmitotic Transcriptional Switch.

TENM3 CHAT

4.01e-041569231812516
Pubmed

Phosphorylation of BACH1 switches its function from transcription factor to mitotic chromosome regulator and promotes its interaction with HMMR.

ZNF131 MAP4 ARHGEF2

4.56e-047569329459360
Pubmed

Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells.

ZNF93 ZNF90

4.57e-04166928467795
Pubmed

Role of topoisomerase IIbeta in the expression of developmentally regulated genes.

TENM3 TOP2B

4.57e-041669216923961
Pubmed

E2F6 associates with BRG1 in transcriptional regulation.

ZBTB17 ZFPM2

5.18e-041769223082233
Pubmed

Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.

ZNF131 ZBTB17

5.18e-04176927557990
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

KLF12 TENM3 ZNF423 REST ARHGEF2 MBD5

6.87e-0453669615840001
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

KLF12 TENM3 ZNF423 REST ARHGEF2 MBD5

7.00e-0453869610512203
Pubmed

Regulation of the protocadherin Celsr3 gene and its role in globus pallidus development and connectivity.

CHAT REST

7.95e-042169225113559
Pubmed

Genome-wide CRISPR Screen to Identify Genes that Suppress Transformation in the Presence of Endogenous KrasG12D.

CCDC18 ATM

9.55e-042369231748650
Pubmed

DEFOG: a practical scheme for deciphering families of genes.

OR7D4 OR1D5 OR1D4 OR1D2

9.60e-0421969412213199
Pubmed

Differentiation and molecular heterogeneity of inhibitory and excitatory neurons associated with midbrain dopaminergic nuclei.

CHAT ZFPM2

1.13e-032569226718003
Pubmed

Isolation and mapping of novel mouse brain cDNA clones containing trinucleotide repeats, and demonstration of novel alleles in recombinant inbred strains.

ANKRD28 CHAT

1.13e-03256928858346
Pubmed

Dystroglycan Maintains Inner Limiting Membrane Integrity to Coordinate Retinal Development.

PRKCB CHAT

1.13e-032569228760865
Pubmed

Mammalian SP/KLF transcription factors: bring in the family.

KLF12 KLF10

1.13e-032569215820306
Pubmed

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

TENM3 DNAH2 MBD5

1.15e-0310369310819331
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

PDLIM7 TRO ZNF423 MATN2 ANKS3 ZFPM2

1.31e-0360869616713569
Pubmed

TERRA transcripts are bound by a complex array of RNA-binding proteins.

PDLIM7 CCDC18

1.42e-032869220975687
Pubmed

Prox2 and Runx3 vagal sensory neurons regulate esophageal motility.

CHAT GRM5

1.52e-032969237192624
Pubmed

Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.

ZNF93 ZNF626

1.52e-032969214563677
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

KLF12 KLHL24 PDLIM7 TRO ATM

1.66e-0343069535044719
Pubmed

Single-cell transcriptomic analysis reveals diversity within mammalian spinal motor neurons.

CHAT GRM5

1.85e-033269236596814
Cytoband19p12

ZNF93 ZNF676 ZNF66 ZNF723 ZNF90 ZNF626

5.20e-099069619p12
CytobandEnsembl 112 genes in cytogenetic band chr19p12

ZNF93 ZNF676 ZNF66 ZNF723 ZNF90 ZNF626

3.25e-08122696chr19p12
Cytoband19q13.43

ZNF419 ZNF587 ZNF772 ZNF417

9.47e-068769419q13.43
Cytoband17p13.3

OR1D5 OR1D4 OR1D2

3.25e-048869317p13.3
Cytoband19p13.2

OR7D4 ZNF560 ZNF846 ZNF763

4.04e-0422969419p13.2
CytobandEnsembl 112 genes in cytogenetic band chr17p13

DNAH2 OR1D5 OR1D4 OR1D2

1.86e-03346694chr17p13
CytobandEnsembl 112 genes in cytogenetic band chr8q22

KLF10 MATN2 ZFPM2

2.11e-03168693chr8q22
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF419 ZNF93 ZNF131 KLF12 ZNF676 ZNF320 ZBTB17 ZNF560 KLF10 ZNF473 ZNF423 ZNF587 ZNF846 ZNF621 ZNF772 ZNF90 ZNF763 ZNF626 ZNF417 ZFPM2

1.13e-15718502028
GeneFamilyOlfactory receptors, family 1

OR1D5 OR1D4 OR1D2

1.83e-0440503147
GeneFamilyZinc fingers C2H2-type|Kruppel like factors

KLF12 KLF10

1.11e-0318502624
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AKAP6 KLF12 ACSM3 PDLIM7 ZFPM2

1.02e-05188685293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCellLung_Parenchyma-Control-Myeloid-Mast_cell|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TDRD15 ZNF560 ANKRD28 PRKCB PRMT9

1.31e-051986850af55f2b859e4626e23e2733bf9ae2ace4547079
ToppCellLung_Parenchyma-Control-Myeloid-Mast_cell-Mast_cells-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TDRD15 ZNF560 ANKRD28 PRKCB PRMT9

1.31e-05198685f75800b4f3cf0d493226db8db7c949caade0ff90
ToppCellParenchyma_Control_(B.)-Immune-TX-Mast_cells|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

TDRD15 ZNF560 ANKRD28 PRKCB PRMT9

1.31e-0519868545089e0adf2c00f4b0bccd701f4daebf25858006
ToppCellLung_Parenchyma-Control-Myeloid-Mast_cell-Mast_cells|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TDRD15 ZNF560 ANKRD28 PRKCB PRMT9

1.31e-051986854163220f4ccb825a8399298cfac8411eb2acc9a2
ToppCell367C-Lymphocytic-ILC-ILC-2|ILC / Donor, Lineage, Cell class and subclass (all cells)

ZNF131 MAP4 ATM

8.19e-05556837916216b3a24f9c6b966aa5392fc2bc43b3d2c4c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF560 TENM3 ZNF423 ZFPM2

1.00e-04158684e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF560 TENM3 ZNF423 ZFPM2

1.00e-04158684d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCellControl-B_cells-Activated_B_cells|Control / group, cell type (main and fine annotations)

PRKCB ATM PRDM2 IL26

1.27e-04168684a7159a35fe37f8c241cf8d391debe271e0698105
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MATN2 ANKRD28 PRMT9 UNC13C

1.33e-041706846c65ddb496030bb479ef346cc37a9d4dfa6b824f
ToppCellCOVID-19-kidney-PEC|kidney / Disease (COVID-19 only), tissue and cell type

ACSM3 TENM3 GRM5 ZFPM2

1.39e-0417268436a96714a0eb6ac438648135336c9791881ddadb
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic-migDC|lymph-node_spleen / Manually curated celltypes from each tissue

CFAP47 TENM3 ZNF423 GRM5

1.39e-041726841b24bed3cd8e3fa463c5e7cefdf9e99e639e2f84
ToppCellE12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ZNF131 PLEKHM3 MBD5 HELB

1.39e-041726843b9be685fcd1634498a603b692f5ac6ddd0de176
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF846 CCDC18 ATM HELB

1.48e-0417568406eace2e681980456299167b48bd49bcfea5e940
ToppCellEndothelial-B-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

ZNF676 TENM3 ZNF423 ZFPM2

1.52e-04176684b288116a4588a1f9db9d49af92cea118937c9201
ToppCellnucseq-Immune-Lymphocytic_B-Lymphocytic_B-B|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KLF12 PRKCB ATM PRDM2

1.69e-041816848d8cc4dae2c8bd5f4b1c159f2a52edc4c9449c86
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

CFAP47 DNAH2 VWA3B GRM5

1.72e-041826847ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellnucseq-Immune-Lymphocytic_B-Lymphocytic_B|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRKCB ATM PRDM2 IL26

1.80e-04184684942b58ae7172bb5f97e55b032db9329d161854af
ToppCellnucseq-Immune-Lymphocytic_B|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRKCB ATM PRDM2 IL26

1.80e-04184684911658e7bb499c1bbc8419eec8ff88729bc39a75
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFAP47 DNAH2 VWA3B GRM5

1.80e-041846845daff849625f2f41d56615569c0ed59cd733b34c
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

CFAP47 DNAH2 VWA3B GRM5

1.83e-0418568430f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellPBMC-Mild-cDC_8|Mild / Compartment, Disease Groups and Clusters

KLF10 ANKRD28 PRMT9 TIPARP

1.83e-04185684891b39c20fe9858fbba90d9ef7a253f1a0870211
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

AKAP6 CFAP47 DNAH2 VWA3B

1.83e-041856845e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AKAP6 KLF12 PDLIM7 ZFPM2

1.87e-041866846add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCellControl-T_cells|Control / group, cell type (main and fine annotations)

KLF12 PRKCB ATM HELB

1.91e-04187684f4e8e0eba58da89b56587667555a5d4754e108c7
ToppCellhuman_hepatoblastoma-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

KLF12 ACSM3 DNAAF9 MBD5

1.91e-04187684f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

AKAP6 KLF12 PDLIM7 UNC13C

1.95e-0418868434e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFAP47 DNAH2 VWA3B GRM5

1.95e-041886842b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

AKAP6 KLF12 PDLIM7 UNC13C

1.99e-041896846b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFAP47 DNAH2 VWA3B GRM5

1.99e-0418968468a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCellASK428-Epithelial-Transformed_epithelium|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

AKAP6 ZNF676 TRO ZFPM2

1.99e-0418968487189275234b5d59484c58acbb14a09903f2b578
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 PDLIM7 MATN2 ZFPM2

2.07e-04191684107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 PDLIM7 MATN2 ZFPM2

2.07e-04191684bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AKAP6 TENM3 PDLIM7 TRO

2.16e-04193684469a7f1c2ff7137cc5a064464456911f67f92e70
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

AKAP6 CFAP47 DNAH2 VWA3B

2.16e-04193684ea345d34440b25f65358a53dc72831998d1c3620
ToppCellCOVID-19-kidney-T-cells-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

KLF12 PRKCB ATM HELB

2.16e-041936845b84fa640cf30dea55fde53b810f850ff946d253
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

AKAP6 CFAP47 DNAH2 VWA3B

2.16e-04193684ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellImmune-T_lymphocyte|World / Lineage, Cell type, age group and donor

KLF12 PRKCB ATM HELB

2.20e-04194684f47fa18c87b35a3960557f8169ff7830dd6ecb80
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-NK-NK-F_2|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZNF419 ZNF93 CCDC18 ZNF626

2.20e-041946845031f324628ff12a33e84cc52157be4786e0961d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 PDLIM7 MATN2 ZFPM2

2.24e-04195684dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 PDLIM7 MATN2 ZFPM2

2.24e-04195684edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 PDLIM7 MATN2 ZFPM2

2.24e-0419568449c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCellmetastatic_Lymph_Node-T/NK_cells-CD4+_Th|T/NK_cells / Location, Cell class and cell subclass

ANKRD28 PRMT9 TIPARP IL26

2.24e-04195684944158240cfc3b2cf72a6601b4e02d8d31a903b9
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ZNF423 PRKCB UNC13C MBD5

2.24e-041956840e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 PDLIM7 MATN2 ZFPM2

2.29e-04196684802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 PDLIM7 MATN2 ZFPM2

2.29e-041966842b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 PDLIM7 MATN2 ZFPM2

2.29e-04196684fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 MATN2 PRKCB ZFPM2

2.33e-041976846d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 PDLIM7 MATN2 ZFPM2

2.33e-0419768480e153790cef37b743e22a7370ff5b3a6abf147d
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AKAP6 CFAP47 DNAH2 VWA3B

2.33e-0419768474a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell10x3'2.3-week_17-19-Lymphocytic_B|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

KLHL24 PRKCB TOP2B PRDM2

2.38e-041986845f465cf5c7493e32d9afe9e9d05757d0a95acc33
ToppCell10x3'2.3-week_17-19-Lymphocytic_B-B_lineage|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

KLHL24 PRKCB TOP2B PRDM2

2.38e-0419868477ce3fe1ab161c0faf8987e73a64ab61294b9255
ToppCellfacs-Tongue-nan-3m-Epithelial-basal_cell_of_epidermis|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL24 KLF10 MATN2 TOP2B

2.38e-0419868422559b161e67b49fe8028bfaf861e069063599f5
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP47 ZNF473 DNAH2 VWA3B

2.42e-04199684542ec45c931b40738df1f3777b00c83be33a514a
ToppCellmLN-ILC|mLN / Region, Cell class and subclass

KLF10 MATN2 ANKRD28 TIPARP

2.42e-04199684d6c299312c747fb1b7c53644c53efc03a5fffe85
ToppCellmLN-(3)_ILC|mLN / shred on region, Cell_type, and subtype

KLF10 MATN2 ANKRD28 TIPARP

2.42e-0419968400e0e2a766dd9c4d0a65f53d88fa50df4b6a3d60
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ACSM3 PDLIM7 MATN2 ZFPM2

2.42e-04199684e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP47 ZNF473 DNAH2 VWA3B

2.42e-041996842498237b9e895ca4826a3378d9d40989968df72b
ToppCellmLN-(3)_ILC-(30)_ILC|mLN / shred on region, Cell_type, and subtype

KLF10 MATN2 ANKRD28 TIPARP

2.42e-0419968433ac6d77099076df01299be429f4ba96f2f34cc1
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ACSM3 PDLIM7 MATN2 ZFPM2

2.42e-0419968438cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCellmLN-ILC-ILC|mLN / Region, Cell class and subclass

KLF10 MATN2 ANKRD28 TIPARP

2.42e-04199684ab09a06cdea2597e9fe4b4b304655e9de4d433f6
ToppCellTracheal-NucSeq-Stromal-Chondrocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TENM3 ZFPM2 PPP4R4 TIPARP

2.47e-04200684b5a54b9baf79aea01f76a161f0a39bbe87eb4945
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP47 ZNF473 DNAH2 VWA3B

2.47e-04200684af6a551f83808c1c839df7ba7b1702ca28ea6e1b
ToppCellTracheal-NucSeq-Stromal-Chondrocytic-Chondrocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TENM3 ZFPM2 PPP4R4 TIPARP

2.47e-04200684f5bd0b30e478dac09f68c46b0781f5f2e7e3c693
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ACSM3 PDLIM7 MATN2 ZFPM2

2.47e-0420068487827041663013f5e7273168dc8709d69840e7ce
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP47 ZNF473 DNAH2 VWA3B

2.47e-0420068473ac1cf40ddd764be1100cbfaaa29563665457d8
ComputationalB lymphoma expression clusters.

ZNF423 ZNF587 ANKRD28 PRKCB

4.18e-04149264MODULE_361
ComputationalGenes in the cancer module 301.

ZNF423 ZNF587 ANKRD28 PRKCB

5.22e-04158264MODULE_301
ComputationalGenes in the cancer module 238.

ZNF423 ZNF587 ANKRD28 PRKCB

6.01e-04164264MODULE_238
Drug3-Acetylcoumarin [3949-36-8]; Down 200; 21.2uM; MCF7; HT_HG-U133A

KLHL24 SLC9A5 MAP4 PDLIM7 VPS50 ATM REST PRDM2

1.34e-071986885259_DN
DrugBetazole hydrochloride; Up 200; 27uM; MCF7; HT_HG-U133A

SLC9A5 ZBTB17 TENM3 MAP4 VPS50 CHAT ARHGEF2 PPP4R4

1.45e-072006885445_UP
DrugTrichlorfon [52-68-6]; Down 200; 15.6uM; MCF7; HT_HG-U133A

ZNF419 ZNF473 TENM3 MAP4 PDLIM7 ATM ARHGEF2

1.77e-061936875989_DN
DrugNS-105

MAP4 CHAT GRM5

3.01e-0610683CID000198695
DrugDipyrone [5907-38-0]; Down 200; 12uM; PC3; HT_HG-U133A

KLHL24 MAP4 ATM REST ARHGEF2 PRDM2

2.09e-051886864310_DN
DrugGuanfacine hydrochloride [29110-48-3]; Down 200; 14.2uM; MCF7; HT_HG-U133A

ZNF419 ZNF473 MAP4 PDLIM7 ATM REST

2.29e-051916862634_DN
DrugMeclozine dihydrochloride [1104-22-9]; Up 200; 8.6uM; MCF7; HT_HG-U133A

KLF12 KLHL24 SLC9A5 PDLIM7 ARHGEF2 PRDM2

2.50e-051946863285_UP
DrugS)-2-amino-2-methyl-4-phosphonobutanoic acid

MAP4 GRM5

2.63e-053682CID001795542
DrugMeclofenoxate hydrochloride [3685-84-5]; Down 200; 13.6uM; MCF7; HT_HG-U133A

MAP4 PDLIM7 ZNF423 REST ARHGEF2 PRDM2

2.80e-051986864729_DN
DrugProxyphylline [603-00-9]; Up 200; 16.8uM; PC3; HT_HG-U133A

ZNF93 KLF12 KLHL24 PDLIM7 REST PRDM2

2.88e-051996867290_UP
DrugPanthenol (D) [81-13-0]; Up 200; 19.4uM; MCF7; HT_HG-U133A

ZNF419 KLHL24 ZNF473 PRKCB REST PRDM2

2.97e-052006867455_UP
Diseaselevel of triacylglycerol (56:6) in blood serum

ZNF93 ZNF90

5.62e-0416652OBA_2020007
Diseaseage-related macular degeneration

REST GRM5 THUMPD2

1.01e-0389653EFO_0001365
DiseaseAutosomal dominant nonsyndromic hearing loss

REST TECTA

1.87e-0329652cv:C5779548

Protein segments in the cluster

PeptideGeneStartEntry
KKAGAHSVYACELSK

PRMT9

196

Q6P2P2
KTYSEFCSRHSKALK

ARHGEF2

336

Q92974
CKDKKSYTPLHAAAS

ANKRD28

201

O15084
KVKTLVFCSGKHFYS

DHTKD1

801

Q96HY7
AKKASYSHNFSKKSS

TIPARP

566

Q7Z3E1
CDYKTADRSNFKKHV

REST

366

Q13127
KYNKTCNSSLTLKTH

GRM5

376

P41594
KKTCTKIDYCASSNH

MATN2

356

O00339
SKKVSYSHIQSKCGS

MAP4

996

P27816
VAFSTSSYSCGRKKK

MGME1

26

Q9BQP7
LSNFITHKKFYCSSH

ZFPM2

1131

Q8WW38
KHKFKIHTYSSPTFC

PRKCB

101

P05771
GKVIKFATSHVYSCS

PLEKHM3

661

Q6ZWE6
KKSSSTYTFCKSVGL

IQSEC3

911

Q9UPP2
YSKKDRPLCKSHAFS

PDLIM7

441

Q9NR12
TKGKYKAFSTCGSHL

OR7D4

231

Q8NG98
IKATFAYISNCHKTK

ATM

1386

Q13315
DTHSLKTLFTKCKNF

KLHL24

176

Q6TFL4
FAKCFHTSFSKCTKL

CCDC18

1336

Q5T9S5
AKHKQSSFTKSCYPR

IL26

21

Q9NPH9
ACYAKTSSLTKAKEV

DNAAF9

386

Q5TEA3
GFEYFKSASCHTSKK

MBD5

1181

Q9P267
DHACKSSARKQAKSY

ANKS3

376

Q6ZW76
CGKTYFKSSHLKAHT

KLF10

376

Q13118
FEGCNKVYTKSSHLK

KLF12

321

Q9Y4X4
AKYKKLLFSLCFFHS

DNAH2

3976

Q9P225
HVYLAFNSICKASTK

CFAP47

511

Q6ZTR5
SSKTNHHSCLYSAVK

HELB

711

Q8NG08
AVSFHKEKSVYLSSK

PRDM2

676

Q13029
VSKKYKAFSTCASHL

OR1D2

231

P34982
ASKKYKTFSTCASHL

OR1D4

231

P47884
ASKKYKTFSTCASHL

OR1D5

231

P58170
SDYNLSSHILKKCSK

MEI4

221

A8MW99
FHAKYGNLEKCASKS

PPP4R4

781

Q6NUP7
TKFTVETACKEYKHS

TOP2B

196

Q02880
CFKVKHDALKTYASL

TMEM126B

96

Q8IUX1
TSKVHNKTVYCEFLK

TDRD15

1431

B5MCY1
ESFKSTKHNICFTKS

SLC9A5

646

Q14940
GFYFDKKSCKSKHQT

AKAP6

1501

Q13023
NDITSYKFKSLKHCV

ACSM3

336

Q53FZ2
FHSCKETSSSKFAKA

CHAT

696

P28329
FSKCHSKVNPTFFYK

TECTA

1311

O75443
STFKHYSCISELNSK

VPS50

211

Q96JG6
CGKAFKYSSALNTHK

ZNF93

206

P35789
CGKAFKSSSTVSYHK

ZNF676

566

Q8N7Q3
KECGKAFIHSSYLTK

ZNF846

341

Q147U1
GKVFSTKAYLACHQK

ZNF320

391

A2RRD8
SYTFKSTVKKIAKCS

UNC13C

56

Q8NB66
SYHETSKMKVLKFAC

TRO

611

Q12816
CYSSVHKKDLKSVVA

RNF10

266

Q8N5U6
NYSCGKRTKAFSTKH

ZNF587

211

Q96SQ5
QCDKYVKVFHKFSSS

ZNF723

146

P0DPD5
NYSCGKRTKAFSTKH

ZNF417

211

Q8TAU3
TCEKAFKYRSNFTKH

ZNF840P

421

A6NDX5
GKTDAFICKYKKSHS

THUMPD2

486

Q9BTF0
LSRSAFKFKKSSKYC

TENM3

291

Q9P273
CGKAFKYSSTLTTHK

ZNF626

346

Q68DY1
KAFKSSYDCIVHEKN

ZNF621

186

Q6ZSS3
KAHKAVLAACSEYFK

ZBTB17

36

Q13105
CDKAFKYSSALSTHK

ZNF90

486

Q03938
EAFKYSCSLTAHKII

ZNF66

376

Q6ZN08
KAHKAVLAACSKFFY

ZNF131

46

P52739
TTHSKKYNCKFCSKA

ZNF423

801

Q2M1K9
SAETNKKTVHAKYCS

VWA3B

436

Q502W6
KQCVKSFSYSATHRI

ZNF763

231

Q0D2J5
SECGKFYSHKSNLIK

ZNF419

346

Q96HQ0
KCSECGKAYSHKSTL

ZNF772

351

Q68DY9
KAFTKCSYLTKHLRT

ZNF560

551

Q96MR9
KCEKTFSCSKYLTQH

ZNF473

566

Q8WTR7