Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH6 DNAH7 DNAH11	1.32e-05	18	52	3	GO:0008569
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH6 DNAH7 DNAH11	5.21e-05	28	52	3	GO:0051959
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH6 DNAH7 DNAH11	1.22e-04	37	52	3	GO:0045505
GeneOntologyMolecularFunction	ATP hydrolysis activity	ATP8B3 ABCD2 POLQ DDX24 DNAH6 DNAH7 DNAH11	1.39e-04	441	52	7	GO:0016887
GeneOntologyMolecularFunction	magnesium ion binding	ATP8B3 DIS3L2 CDC42BPA POLQ ME1	4.50e-04	247	52	5	GO:0000287
GeneOntologyMolecularFunction	single-stranded DNA endodeoxyribonuclease activity	SETMAR POLQ	5.09e-04	13	52	2	GO:0000014
GeneOntologyMolecularFunction	peptidase activator activity	ROCK2 CASP8AP2 PSME2	8.06e-04	70	52	3	GO:0016504
GeneOntologyMolecularFunction	microtubule motor activity	DNAH6 DNAH7 DNAH11	8.06e-04	70	52	3	GO:0003777
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	ATP8B3 ABCD2 POLQ DDX24 DNAH6 DNAH7 MX1 DNAH11	8.23e-04	775	52	8	GO:0017111
GeneOntologyMolecularFunction	ATP-dependent activity	ATP8B3 ABCD2 POLQ DDX24 DNAH6 DNAH7 DNAH11	1.01e-03	614	52	7	GO:0140657
GeneOntologyMolecularFunction	endopeptidase activator activity	ROCK2 PSME2	1.11e-03	19	52	2	GO:0061133
GeneOntologyMolecularFunction	pyrophosphatase activity	ATP8B3 ABCD2 POLQ DDX24 DNAH6 DNAH7 MX1 DNAH11	1.37e-03	839	52	8	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	ATP8B3 ABCD2 POLQ DDX24 DNAH6 DNAH7 MX1 DNAH11	1.38e-03	840	52	8	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	ATP8B3 ABCD2 POLQ DDX24 DNAH6 DNAH7 MX1 DNAH11	1.38e-03	840	52	8	GO:0016818
GeneOntologyMolecularFunction	ribonucleoprotein complex binding	GEMIN4 SEC61A1 GCN1 PTCD3	2.02e-03	206	52	4	GO:0043021
GeneOntologyCellularComponent	inner dynein arm	DNAH6 DNAH7	2.70e-04	10	52	2	GO:0036156
GeneOntologyCellularComponent	dynein complex	DNAH6 DNAH7 DNAH11	3.29e-04	54	52	3	GO:0030286
Domain	Dynein_heavy_chain_D4_dom	DNAH6 DNAH7 DNAH11	6.84e-06	14	51	3	IPR024317
Domain	Dynein_HC_stalk	DNAH6 DNAH7 DNAH11	6.84e-06	14	51	3	IPR024743
Domain	Dynein_heavy_dom-2	DNAH6 DNAH7 DNAH11	6.84e-06	14	51	3	IPR013602
Domain	DHC_N2	DNAH6 DNAH7 DNAH11	6.84e-06	14	51	3	PF08393
Domain	MT	DNAH6 DNAH7 DNAH11	6.84e-06	14	51	3	PF12777
Domain	AAA_8	DNAH6 DNAH7 DNAH11	6.84e-06	14	51	3	PF12780
Domain	DHC_fam	DNAH6 DNAH7 DNAH11	8.53e-06	15	51	3	IPR026983
Domain	Dynein_heavy_dom	DNAH6 DNAH7 DNAH11	8.53e-06	15	51	3	IPR004273
Domain	Dynein_heavy	DNAH6 DNAH7 DNAH11	8.53e-06	15	51	3	PF03028
Domain	Transc_factor_DP_C	TFDP1 TFDP2	2.19e-05	3	51	2	IPR014889
Domain	DP	TFDP1 TFDP2	2.19e-05	3	51	2	PF08781
Domain	DP	TFDP1 TFDP2	2.19e-05	3	51	2	SM01138
Domain	Transcrpt_fac_DP	TFDP1 TFDP2	2.19e-05	3	51	2	IPR015648
Domain	E2F_TDP	TFDP1 TFDP2	3.96e-04	11	51	2	PF02319
Domain	E2F_TDP	TFDP1 TFDP2	3.96e-04	11	51	2	SM01372
Domain	E2F_WHTH_DNA-bd_dom	TFDP1 TFDP2	3.96e-04	11	51	2	IPR003316
Domain	AAA+_ATPase	ABCD2 DNAH6 DNAH7 DNAH11	6.39e-04	144	51	4	IPR003593
Domain	AAA	ABCD2 DNAH6 DNAH7 DNAH11	6.39e-04	144	51	4	SM00382
Domain	ATPase_dyneun-rel_AAA	DNAH6 DNAH11	6.51e-04	14	51	2	IPR011704
Domain	AAA_5	DNAH6 DNAH11	6.51e-04	14	51	2	PF07728
Domain	-	ABCD2 POLQ DDX24 DNAH6 DNAH7 MX1 DNAH11	3.95e-03	746	51	7	3.40.50.300
Domain	Pkinase_C	ROCK2 CDC42BPA	4.58e-03	37	51	2	IPR017892
Domain	SET	SETMAR PRDM2	5.60e-03	41	51	2	PF00856
Domain	TPR_repeat	RANBP2 SUGT1 AIP	5.73e-03	133	51	3	IPR019734
Domain	Pkinase_C	ROCK2 CDC42BPA	5.87e-03	42	51	2	PF00433
Domain	SET	SETMAR PRDM2	7.01e-03	46	51	2	SM00317
Domain	P-loop_NTPase	ABCD2 POLQ DDX24 DNAH6 DNAH7 MX1 DNAH11	7.87e-03	848	51	7	IPR027417
Domain	TPR-contain_dom	RANBP2 SUGT1 AIP	7.98e-03	150	51	3	IPR013026
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT	DNAH6 DNAH7 DNAH11	7.35e-05	27	43	3	M47755
Pathway	REACTOME_ACTIVATION_OF_NOXA_AND_TRANSLOCATION_TO_MITOCHONDRIA	TFDP1 TFDP2	9.04e-05	5	43	2	M26903
Pathway	KEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT	DNAH6 DNAH7 DNAH11	3.00e-04	43	43	3	M47669
Pathway	REACTOME_ACTIVATION_OF_PUMA_AND_TRANSLOCATION_TO_MITOCHONDRIA	TFDP1 TFDP2	3.23e-04	9	43	2	M26946
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT	DNAH6 DNAH7 DNAH11	3.43e-04	45	43	3	M47670
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	RANBP2 SF3B3 DST SUGT1 NSA2 RRS1 NUP133 GEMIN4 PSME2 DDX24 SEC61A1 GCN1 MX1 PTCD3	2.16e-08	1440	53	14	30833792
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	RANBP2 DST NSA2 RRS1 NUP133 GEMIN4 DDX24 GCN1 CAP1 PTCD3	4.79e-08	653	53	10	22586326
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	RANBP2 DIS3L2 SF3B3 DST SUGT1 NSA2 RRS1 NUP133 GEMIN4 DDX24 GCN1 CAP1 PTCD3	8.70e-08	1353	53	13	29467282
Pubmed	The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.	DST SUGT1 NSA2 RRS1 MRPL37 AIP DDX24 TFDP1 PTCD3	1.32e-07	547	53	9	37267103
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	CASP8AP2 RANBP2 DST RESF1 GEMIN4 GCN1 TFDP1 PRDM2	2.25e-07	418	53	8	34709266
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	DST SUGT1 LYPLAL1 NSA2 RRS1 ALDH1L2 MRPL37 NUP133 GEMIN4 AIP DDX24 SEC61A1 PTCD3	2.76e-07	1496	53	13	32877691
Pubmed	Scanning the human proteome for calmodulin-binding proteins.	CASP8AP2 RANBP2 DST DOCK11 MORF4L1	3.01e-07	92	53	5	15840729
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	RANBP2 SF3B3 RRS1 MRPL37 NUP133 GEMIN4 DDX24 SEC61A1 GCN1 PRDM2 CAP1 PTCD3	1.20e-06	1425	53	12	30948266
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH6 DNAH7 DNAH11	1.20e-06	14	53	3	9373155
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	CASP8AP2 SF3B3 CDC42BPA SUGT1 RRS1 MRPL37 NUP133 AIP DDX24 SEC61A1 TFDP1 PTCD3	1.87e-06	1487	53	12	33957083
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	ROCK2 RANBP2 SF3B3 CDC42BPA SUGT1 PSME2 DDX24 ME1 SEC61A1 GCN1 CAP1	2.30e-06	1247	53	11	27684187
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	ROCK2 RANBP2 SF3B3 MORF4L1 NUP133 GEMIN4 POLQ DDX24 SEC61A1 GCN1 PTCD3	3.05e-06	1284	53	11	17353931
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	RANBP2 SF3B3 RESF1 SUGT1 MORF4L1 MRPL37 PEG3 AIP PSME2 DDX24 PTCD3	4.42e-06	1335	53	11	29229926
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	RANBP2 SF3B3 DST CDC42BPA RRS1 MORF4L1 DDX24 SEC61A1 GCN1 PTCD3	4.71e-06	1082	53	10	38697112
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	RANBP2 SF3B3 CDC42BPA NSA2 RRS1 NUP133 GEMIN4 DDX24 SEC61A1	4.90e-06	847	53	9	35850772
Pubmed	Dp1 is largely dispensable for embryonic development.	TFDP1 TFDP2	6.83e-06	3	53	2	15282318
Pubmed	Genomic structure and developmental expression of the mouse cell cycle regulatory transcription factor DP1.	TFDP1 TFDP2	6.83e-06	3	53	2	9000141
Pubmed	Human transcription factor protein interaction networks.	DST CDC42BPA RESF1 NSA2 MORF4L1 MRPL37 DDX24 TFDP1 TFDP2 PRDM2 PTCD3	8.43e-06	1429	53	11	35140242
Pubmed	Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family.	TRAF7 SUGT1 ACAD11 DOCK11 RRS1 GEMIN4 AIP SEC61A1 CAP1	1.05e-05	931	53	9	27432908
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	RANBP2 SUGT1 LYPLAL1 MRPL37 NUP133 DDX24 SEC61A1 GCN1	1.08e-05	704	53	8	29955894
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	ROCK2 RANBP2 SF3B3 DST CDC42BPA GEMIN4 GCN1 CAP1	1.12e-05	708	53	8	39231216
Pubmed	Genomic cloning and chromosomal assignment of the E2F dimerization partner TFDP gene family.	TFDP1 TFDP2	1.36e-05	4	53	2	9027491
Pubmed	E2F-6: a novel member of the E2F family is an inhibitor of E2F-dependent transcription.	TFDP1 TFDP2	1.36e-05	4	53	2	9704927
Pubmed	Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinases.	ROCK2 CDC42BPA	1.36e-05	4	53	2	17344417
Pubmed	DP-2, a heterodimeric partner of E2F: identification and characterization of DP-2 proteins expressed in vivo.	TFDP1 TFDP2	1.36e-05	4	53	2	8755520
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	ROCK2 RANBP2 ACAD11 NUP133 GEMIN4 AIP SEC61A1 GCN1 PTCD3	1.50e-05	974	53	9	28675297
Pubmed	Primary Ciliary Dyskinesia Associated Disease-Causing Variants in CCDC39 and CCDC40 Cause Axonemal Absence of Inner Dynein Arm Heavy Chains DNAH1, DNAH6, and DNAH7.	DNAH6 DNAH7	2.27e-05	5	53	2	39056782
Pubmed	Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS.	NSA2 RRS1 SEC61A1 MX1 PTCD3	2.57e-05	228	53	5	30471916
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	ROCK2 RANBP2 SF3B3 SUGT1 MORF4L1 GEMIN4 GCN1	2.81e-05	582	53	7	20467437
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	TRAF7 RESF1 MRPL37 DDX24 GCN1 PTCD3	3.07e-05	396	53	6	26687479
Pubmed	Repression of transcriptional activity of C/EBPalpha by E2F-dimerization partner complexes.	TFDP1 TFDP2	3.40e-05	6	53	2	20176812
Pubmed	ICAP-1 monoubiquitylation coordinates matrix density and rigidity sensing for cell migration through ROCK2-MRCKα balance.	ROCK2 CDC42BPA	3.40e-05	6	53	2	28049720
Pubmed	Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor.	RANBP2 SF3B3 GEMIN4 SEC61A1 GCN1 TFDP1	3.62e-05	408	53	6	33766124
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	RANBP2 DST RESF1 SUGT1	3.81e-05	123	53	4	26912792
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TRAF7 SF3B3 RESF1 ACAD11 MORF4L1 DDX24 TFDP1 TFDP2 PTCD3	4.35e-05	1116	53	9	31753913
Pubmed	ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division.	RANBP2 NUP133	4.76e-05	7	53	2	17098863
Pubmed	MRCKα is activated by caspase cleavage to assemble an apical actin ring for epithelial cell extrusion.	ROCK2 CDC42BPA	4.76e-05	7	53	2	29162624
Pubmed	Dp1 is required for extra-embryonic development.	TFDP1 TFDP2	4.76e-05	7	53	2	12588846
Pubmed	In vivo association of E2F and DP family proteins.	TFDP1 TFDP2	4.76e-05	7	53	2	7739537
Pubmed	E2F-6, a member of the E2F family that can behave as a transcriptional repressor.	TFDP1 TFDP2	4.76e-05	7	53	2	9501179
Pubmed	A protein interaction landscape of breast cancer.	DST RRS1 MORF4L1 DDX24 TFDP1 TFDP2 PTCD3	4.82e-05	634	53	7	34591612
Pubmed	Human Regulatory Protein Ki-1/57 Is a Target of SUMOylation and Affects PML Nuclear Body Formation.	NSA2 RRS1 MRPL37 DDX24	5.33e-05	134	53	4	28695742
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	RANBP2 SF3B3 DST GEMIN4 AIP ME1 GCN1 CAP1 PTCD3	5.44e-05	1149	53	9	35446349
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	RANBP2 SF3B3 NUP133 GEMIN4 SEC61A1 GCN1 TFDP1	6.03e-05	657	53	7	36180527
Pubmed	Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release.	TFDP1 TFDP2	6.34e-05	8	53	2	16360038
Pubmed	Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.	TRAF7 ACAD11 MORF4L1 AIP SEC61A1	7.18e-05	283	53	5	21903422
Pubmed	A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.	DST SUGT1 PEG3 GCN1 PRDM2	7.30e-05	284	53	5	29459677
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	RANBP2 MORF4L1 NUP133 SEC61A1 GCN1 PTCD3	7.82e-05	469	53	6	27634302
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	RANBP2 DST SUGT1 RRS1 MRPL37 NUP133 PSME2 GCN1	7.98e-05	934	53	8	33916271
Pubmed	R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.	SF3B3 CDC42BPA ACAD11 GEMIN4 SEC61A1	9.44e-05	300	53	5	28561026
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	CDC42BPA ACAD11 RRS1 GEMIN4 DDX24 GCN1 PTCD3	1.00e-04	713	53	7	29802200
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	SF3B3 ACAD11 NSA2 ALDH1L2 MORF4L1 PSME2 DDX24 PTCD3	1.04e-04	971	53	8	33306668
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	RANBP2 DST CDC42BPA MORF4L1 PEG3 NUP133	1.07e-04	497	53	6	23414517
Pubmed	Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.	ENDOD1 LYPLAL1 SEC61A1 GCN1 TFDP1 TFDP2	1.10e-04	499	53	6	22810586
Pubmed	An investigation into the human serum "interactome".	RANBP2 PEG3 GCN1 IGDCC4	1.11e-04	162	53	4	15174051
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	RANBP2 SF3B3 NSA2 RRS1 MORF4L1 DDX24 SEC61A1 PTCD3	1.19e-04	989	53	8	36424410
Pubmed	Genome-wide CRISPR-cas9 knockout screening identifies GRB7 as a driver for MEK inhibitor resistance in KRAS mutant colon cancer.	RANBP2 GEMIN4 DDX24	1.24e-04	63	53	3	34718347
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	ROCK2 ENDOD1 DST SUGT1 LYPLAL1 MORF4L1 AIP PSME2 SEC61A1	1.37e-04	1297	53	9	33545068
Pubmed	ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.	SF3B3 NSA2 RRS1 DDX24 PTCD3	1.47e-04	330	53	5	33301849
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RANBP2 CDC42BPA SUGT1 NUP133 AIP ME1 SEC61A1 GCN1	1.77e-04	1049	53	8	27880917
Pubmed	Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence.	TFDP1 TFDP2	2.05e-04	14	53	2	17531812
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	CDC42BPA ACAD11 NSA2 RRS1 PEG3 GEMIN4 AIP GCN1 PTCD3	2.07e-04	1371	53	9	36244648
Pubmed	In vitro nuclear interactome of the HIV-1 Tat protein.	RANBP2 SF3B3 DDX24 GCN1	2.26e-04	195	53	4	19454010
Pubmed	HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.	RANBP2 RRS1 NUP133 PSME2 SEC61A1 GCN1	2.28e-04	571	53	6	37167062
Pubmed	FBXO3 Protein Promotes Ubiquitylation and Transcriptional Activity of AIRE (Autoimmune Regulator).	SF3B3 GCN1	2.36e-04	15	53	2	27365398
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	RANBP2 RESF1 SUGT1 MORF4L1 AIP PSME2 PRDM2 CAP1	2.49e-04	1103	53	8	34189442
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	RANBP2 SF3B3 CDC42BPA GCN1	2.59e-04	202	53	4	24639526
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	ROCK2 RANBP2 SF3B3 MORF4L1 GEMIN4 PSME2 DDX24 GCN1 PTCD3	2.62e-04	1415	53	9	28515276
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	ROCK2 POLQ SEC61A1 PRDM2	2.89e-04	208	53	4	33230847
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	ROCK2 RANBP2 SF3B3 DST NSA2 RRS1 POLQ SEC61A1 DNAH6	3.01e-04	1442	53	9	35575683
Pubmed	Screening E3 substrates using a live phage display library.	RESF1 PRDM2	3.05e-04	17	53	2	24124579
Pubmed	The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma.	POLQ DNAH11	3.05e-04	17	53	2	23502783
Pubmed	FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells.	MORF4L1 MRPL37 DDX24 SEC61A1	3.11e-04	212	53	4	33462405
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	DST NUP133 AIP SEC61A1	3.11e-04	212	53	4	33853758
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	RANBP2 SETMAR MRPL37 NUP133 SEC61A1 TFDP1	3.13e-04	606	53	6	36538041
Pubmed	CRISPR/Cas9-mediated Genomic Editing of Cluap1/IFT38 Reveals a New Role in Actin Arrangement.	SUGT1 ACAD11 ALDH1L2 PSME2	3.17e-04	213	53	4	29615496
Pubmed	BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion.	RANBP2 NUP133 GCN1 CAP1	3.34e-04	216	53	4	31519766
Pubmed	PTENα and PTENβ promote carcinogenesis through WDR5 and H3K4 trimethylation.	RANBP2 GEMIN4 DDX24 SEC61A1	3.40e-04	217	53	4	31685992
Pubmed	The RNA-binding protein HuR is a novel target of Pirh2 E3 ubiquitin ligase.	RANBP2 SF3B3 NUP133 PTCD3	3.58e-04	220	53	4	34091597
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	RANBP2 RESF1 ACAD11 POLQ	3.70e-04	222	53	4	37071664
Pubmed	Proteomic and yeast 2-hybrid screens to identify PTEN binding partners.	RANBP2 SF3B3 CDC42BPA SUGT1	3.96e-04	226	53	4	37839992
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	RANBP2 DST CDC42BPA ACAD11 NSA2 RRS1 MORF4L1 GEMIN4 PTCD3	3.96e-04	1497	53	9	31527615
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	DST NSA2 RRS1 DDX24 PTCD3	4.01e-04	410	53	5	26949251
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	RANBP2 SF3B3 NUP133 GEMIN4 GCN1 CAP1	4.11e-04	638	53	6	33239621
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	ACAD11 PIRT NSA2 MRPL37 DNAH7 DNAH11	4.11e-04	638	53	6	31182584
Pubmed	Nucleolar proteome dynamics.	NSA2 RRS1 MORF4L1 DDX24 GCN1	4.42e-04	419	53	5	15635413
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	TRAF7 DST CDC42BPA ACAD11 NUP133 AIP TFDP2	4.43e-04	910	53	7	36736316
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	DST RESF1 DNAH7 DNAH11	4.44e-04	233	53	4	37704626
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	SF3B3 DST CDC42BPA DDX24	4.52e-04	234	53	4	36243803
Pubmed	mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells.	DST TFDP1 TFDP2	4.59e-04	98	53	3	34943047
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	DST SUGT1 ACAD11 DOCK11 AIP	5.87e-04	446	53	5	24255178
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	RANBP2 SF3B3 SUGT1 MRPL37 NUP133 GEMIN4 SEC61A1 GCN1	5.95e-04	1257	53	8	37317656
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	SF3B3 DST NSA2 RRS1 NUP133 GEMIN4 DDX24 PTCD3	5.95e-04	1257	53	8	36526897
Pubmed	SOCS2 Binds to and Regulates EphA2 through Multiple Mechanisms.	DST SUGT1 SEC61A1	6.43e-04	110	53	3	28883622
Pubmed	Tumor-derived neomorphic mutations in ASXL1 impairs the BAP1-ASXL1-FOXK1/K2 transcription network.	GEMIN4 SEC61A1 GCN1	6.60e-04	111	53	3	32683582
Pubmed	Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein, whereas export is due to a nuclear export signal sequence in glucokinase.	RANBP2 NUP133	6.68e-04	25	53	2	10601273
Pubmed	Stasimon/Tmem41b localizes to mitochondria-associated ER membranes and is essential for mouse embryonic development.	GEMIN4 SEC61A1 GCN1	6.95e-04	113	53	3	30352685
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	CASP8AP2 RANBP2 SF3B3 DST MORF4L1 NUP133 DDX24 PRDM2	7.19e-04	1294	53	8	30804502
Pubmed	Docking of HIV-1 Vpr to the nuclear envelope is mediated by the interaction with the nucleoporin hCG1.	RANBP2 NUP133	7.23e-04	26	53	2	12228227
Pubmed	MxA interacts with and is modified by the SUMOylation machinery.	CASP8AP2 MX1	7.80e-04	27	53	2	25447205
Interaction	SIRT7 interactions	RANBP2 DST NSA2 RRS1 NUP133 GEMIN4 PSME2 DDX24 GCN1 CAP1 PTCD3	2.44e-06	744	52	11	int:SIRT7
Interaction	NUP43 interactions	CASP8AP2 RANBP2 DST RESF1 SUGT1 RRS1 NUP133 DDX24 TFDP1 PRDM2	3.74e-06	625	52	10	int:NUP43
Interaction	RPS6KL1 interactions	RANBP2 SUGT1 NUP133 GCN1	9.00e-06	51	52	4	int:RPS6KL1
Interaction	KCNA3 interactions	ROCK2 RANBP2 SF3B3 DST CDC42BPA GEMIN4 POLQ SEC61A1 GCN1 PRDM2 CAP1	1.10e-05	871	52	11	int:KCNA3
Interaction	FBXL6 interactions	DST SUGT1 NSA2 RRS1 MRPL37 AIP DDX24 TFDP1 PTCD3	1.62e-05	583	52	9	int:FBXL6
Interaction	USP19 interactions	SF3B3 AIP ME1 SEC61A1 GCN1	4.75e-05	154	52	5	int:USP19
Interaction	DUSP2 interactions	RANBP2 NUP133 AIP GCN1	5.66e-05	81	52	4	int:DUSP2
Interaction	RNF2 interactions	RANBP2 SF3B3 NSA2 MORF4L1 NUP133 DDX24 GCN1 TFDP1 TFDP2 PTCD3	6.24e-05	866	52	10	int:RNF2
Interaction	KDM1A interactions	CASP8AP2 RANBP2 DST RESF1 SUGT1 GEMIN4 ZFP28 GCN1 TFDP1 PRDM2	1.24e-04	941	52	10	int:KDM1A
Interaction	MCIDAS interactions	TFDP1 TFDP2	1.36e-04	7	52	2	int:MCIDAS
Interaction	KLF12 interactions	MRPL37 DDX24 TFDP1 PRDM2 PTCD3	1.41e-04	194	52	5	int:KLF12
Interaction	FGFR3 interactions	SUGT1 NSA2 MRPL37 AIP SEC61A1 PTCD3	1.55e-04	315	52	6	int:FGFR3
Cytoband	12p11.21	RESF1 OVOS2	2.98e-04	22	53	2	12p11.21
GeneFamily	Dyneins, axonemal	DNAH6 DNAH7 DNAH11	3.37e-06	17	32	3	536
GeneFamily	Transcription factor Dp family	TFDP1 TFDP2	9.09e-06	3	32	2	987
GeneFamily	Endogenous ligands\|Minor histocompatibility antigens	RESF1 NUP133 GEMIN4	9.90e-05	51	32	3	870
GeneFamily	Nucleoporins	RANBP2 NUP133	1.46e-03	32	32	2	1051
Coexpression	GSE29617_CTRL_VS_DAY3_TIV_FLU_VACCINE_PBMC_2008_UP	RANBP2 ZFP28 DDX24 DNAH6 PRDM2 PTCD3	2.48e-06	196	52	6	M4928
Coexpression	GSE32986_UNSTIM_VS_GMCSF_STIM_DC_DN	RANBP2 SF3B3 RXYLT1 PSME2 DDX24 PRDM2	2.70e-06	199	52	6	M8641
Coexpression	GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_MAC_DN	RANBP2 CXCL13 PSME2 MX1 CAP1	4.67e-05	199	52	5	M5242
Coexpression	PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_DN	ENDOD1 RESF1 PEG3 CAP1	6.11e-05	107	52	4	MM947
Coexpression	PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_DN	ENDOD1 RESF1 PEG3 CAP1	6.57e-05	109	52	4	M2451
ToppCell	facs-Trachea-3m\|Trachea / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ROCK2 DST CDC42BPA MORF4L1 PEG3 SEC61A1	1.26e-07	197	53	6	e77016d64b1cac9825fec7cfe5071f1567401187
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROCK2 DST CDC42BPA SLC26A2 ME1	1.96e-06	173	53	5	e1378201b15ffb98e196ac39fe3ee4b4078953bd
ToppCell	facs-Large_Intestine-Proximal-3m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROCK2 DST CDC42BPA SLC26A2 ME1	1.96e-06	173	53	5	99532bb768ee35fed939a377acb5215d3f8904bd
ToppCell	facs-Trachea-nan-3m\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROCK2 DST CDC42BPA MORF4L1 SEC61A1	3.70e-06	197	53	5	0353d925ee4b7aefc2c51b5fab873f465cdf9ebc
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CASP8AP2 RESF1 PEG3 SLC10A6	3.57e-05	156	53	4	53ded973358e3e48054130131e959f0d1f4ef60f
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Ciliated_2\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	KCNAB1 DNAH6 DNAH7 DNAH11	4.44e-05	165	53	4	731147b4337fd0de4383dc8170b4f9ccd98caec6
ToppCell	ileum\|World / shred on tissue and cell subclass	ROCK2 DST RESF1 SLC26A2	4.99e-05	170	53	4	9f1211bd4287620e19a59f21e6ecdca3e42e0260
ToppCell	BAL-Mild-cDC_12\|Mild / Compartment, Disease Groups and Clusters	ACAD11 GEMIN4 ZFP28 ABCD2	6.92e-05	185	53	4	e867ed55ab0df018f14bca824da09d36d83e12f9
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 DNAH6 DNAH7 DNAH11	7.52e-05	189	53	4	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	droplet-Limb_Muscle-MUSCLE\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROCK2 RANBP2 PEG3 PRDM2	8.32e-05	194	53	4	e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell	Control-PLT_1\|Control / Disease Group and Platelet Clusters	ROCK2 LYPLAL1 MORF4L1 CAP1	8.49e-05	195	53	4	20ee45983a5675d9fa072d02dd45c6ce8662d7d7
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ATP8B3 DNAH6 DNAH7 DNAH11	8.83e-05	197	53	4	861e8df9bd74dc5e17bafdc1fb3fef546753c73a
ToppCell	mild-MAIT\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RESF1 DDX24 ME1 MX1	9.18e-05	199	53	4	cbe1fb6d2c5fca7a1baf1ad20afcdf8e8e11bd84
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	RESF1 DDX24 PRDM2 MX1	9.36e-05	200	53	4	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	mild-CD8+_T_naive\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RESF1 NSA2 ABCD2 MX1	9.36e-05	200	53	4	c825320599a61a4c629d736f5c0fd6f1f405540a
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RESF1 DDX24 PRDM2 MX1	9.36e-05	200	53	4	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	VE\|World / Condition, Cell_class and T cell subcluster	RESF1 NSA2 PSME2 MX1	9.36e-05	200	53	4	8ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCell	LPS_only-Unknown\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC9A5 SLC10A6 ABCD2	3.47e-04	115	53	3	7a733f6987b40ec497a03734b79ed5355ad3a2fc
ToppCell	LPS_only-Unknown-Endothelial-Pericyte_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC9A5 SLC10A6 ABCD2	3.47e-04	115	53	3	c67145d3cd9243994a141749b426ff2a6dcc8d93
ToppCell	LPS_only-Unknown-Endothelial\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC9A5 SLC10A6 ABCD2	3.47e-04	115	53	3	ad5298c2ad8bf94fa13c2e50b0799e929473ef59
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-6\|TCGA-Thryoid / Sample_Type by Project: Shred V9	KCNAB1 IGDCC4 DNAH11	5.19e-04	132	53	3	b7611c6a5c86908132e7ab3e41d67277e8142db1
ToppCell	(08)_Brush+PNEC-(2)_GFP_FOXI1\|(08)_Brush+PNEC / shred by cell type by condition	ROCK2 CDC42BPA SLC26A2	5.91e-04	138	53	3	817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-Airway\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GEMIN4 DNAH6 GCN1	6.04e-04	139	53	3	6396434c1cb209193ccdf15581ec2adacf941d85
ToppCell	metastatic_Brain-T/NK_cells-Naive_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	ACAD11 SLC26A2 OVOS2	7.10e-04	147	53	3	4f7a0c287721befeffabf95b8c5f9ff64149c7c1
ToppCell	LPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH6 DNAH7 DNAH11	7.24e-04	148	53	3	d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SUGT1 ZFP28 RXYLT1	7.24e-04	148	53	3	065177aaa63c0441d312260b43ecdac78c84ad03
ToppCell	LPS-antiTNF-Epithelial_airway-Ciliated_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH6 DNAH7 DNAH11	7.24e-04	148	53	3	c8e93b87212f55774223caa385859c566fa1981f
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DST SLC10A6 TFDP2	7.53e-04	150	53	3	aa11579a57d671a55e64183d35c1340fda6dec14
ToppCell	COVID-19-Epithelial_cells-Airway_mucous\|COVID-19 / group, cell type (main and fine annotations)	DNAH6 DNAH7 DNAH11	7.68e-04	151	53	3	8216462e723fec2797387929dde095370947e10a
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DST SLC10A6 TFDP2	7.97e-04	153	53	3	82b77c8bae49dd63b8f10eb67df66ca71d0bb315
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CASP8AP2 RESF1 PEG3	7.97e-04	153	53	3	7480522a47e367f8facc4f5d599fbaf0b5ad4007
ToppCell	Control-Epithelial_airway-Ciliated_cells\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH6 DNAH7 DNAH11	8.13e-04	154	53	3	7556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCell	Control-Epithelial_airway-Ciliated_cells-Ciliated\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH6 DNAH7 DNAH11	8.13e-04	154	53	3	4e3bc24043144143842627cacf6f90dda2228910
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH6 DNAH7 DNAH11	8.13e-04	154	53	3	58072ce422d09f2de602580325eaac6c4ec6c136
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells-Ciliated\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH6 DNAH7 DNAH11	8.13e-04	154	53	3	9ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH6 DNAH7 DNAH11	8.28e-04	155	53	3	5f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH6 DNAH7 DNAH11	8.28e-04	155	53	3	0944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TRAF7 DIS3L2 DNAH7	8.43e-04	156	53	3	abea3c183d32062b009a79a2bdf861021989c7ef
ToppCell	NS-moderate-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH6 DNAH7 DNAH11	8.59e-04	157	53	3	410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell	Adult-Immune-mast_cell-D175\|Adult / Lineage, Cell type, age group and donor	SLC9A5 CXCL13 TFDP1	8.91e-04	159	53	3	9f53fe2e0f25448d62a591c8e528e9a49b5400d5
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Fibroblasts-MatrixFB_->_Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ACAD11 PEG3 IGDCC4	9.07e-04	160	53	3	778faada072e3abfa76a9a06fd4885fb63de7902
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-1\|TCGA-Kidney / Sample_Type by Project: Shred V9	ACAD11 SLC10A6 KCNAB1	9.24e-04	161	53	3	6cacae4a759ace763597ee394cff498dc5d96f74
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CASP8AP2 CDC42BPA KCNAB1	9.57e-04	163	53	3	1feb4ef7b8abcfca9a72c8d13c40548de79e7db2
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TRAF7 DIS3L2 DNAH7	9.92e-04	165	53	3	436ce4bc75e1ba4351c439ccad19f84ad5bcb92f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RRS1 MRPL37 SEC61A1	9.92e-04	165	53	3	50f1fa7434ebb777e15d5273d1ff41070cff6db3
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TRAF7 DIS3L2 DNAH7	9.92e-04	165	53	3	242bdb7654f415391fb8e9bdc06412c7eee9c97e
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CASP8AP2 ALDH1L2 POLQ	1.01e-03	166	53	3	f4698fd08965936d51695d571bd10fb77330d916
ToppCell	lung-Ciliated_Epithelia\|lung / shred on tissue and cell subclass	DNAH6 DNAH7 DNAH11	1.03e-03	167	53	3	26cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GSTT4 DNAH6 DNAH11	1.04e-03	168	53	3	9a8709d34865cfa668d8f3335dc34fc86fc32482
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH6 DNAH7 DNAH11	1.06e-03	169	53	3	fba841664939c771881ba97f14ef1df6635c04ff
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH6 DNAH7 DNAH11	1.06e-03	169	53	3	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CXCL13 DNAH6 DNAH11	1.06e-03	169	53	3	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SLC10A6 MX1 PTCD3	1.08e-03	170	53	3	ba4ba66b624089ed50a9083176386c7941b4c7a3
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TRAF7 AIP DNAH7	1.08e-03	170	53	3	0f215911b5880eeffeb43230f7eeaf55b612eaf2
ToppCell	droplet-Liver-nan-3m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROCK2 RXYLT1 POLQ	1.12e-03	172	53	3	f814b6134ad608015765399d54cc1e5e1873ed34
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST SLC10A6 CXCL13	1.12e-03	172	53	3	7295bf3ae21a61dd6bcfa0dfb7a37d0f3e8f94ab
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	CASP8AP2 ALDH1L2 POLQ	1.12e-03	172	53	3	e9b97f37bb1732ad9aa89c5e9b513d14022801ac
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH6 DNAH7 DNAH11	1.14e-03	173	53	3	c3762655caa79ac4879876f470d32578a3c93b01
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 DNAH7 DNAH11	1.17e-03	175	53	3	284fdc7a9d303636a637041846850d19d114861a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_26.46.91\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CASP8AP2 SLC9A5 GEMIN4	1.19e-03	176	53	3	29b71369503719c74888cd356ceb6724cfdcabd9
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-nan\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROCK2 CDC42BPA SLC26A2	1.19e-03	176	53	3	1dd54bfaa58541de51e5a8328651d390833bd480
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROCK2 RANBP2 PEG3	1.19e-03	176	53	3	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ROCK2 KCNAB1 DNAH11	1.21e-03	177	53	3	a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ROCK2 KCNAB1 DNAH11	1.21e-03	177	53	3	3645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCell	Ciliated_cells-B-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	DNAH6 DNAH7 DNAH11	1.21e-03	177	53	3	c38138fb5ad9766c2d240811210c854338cd612e
ToppCell	Severe-B_intermediate-10\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	RESF1 DDX24 MX1	1.23e-03	178	53	3	b7374a97c51239782bed658381a02cb1b3d9bf66
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DNAH6 DNAH7 DNAH11	1.23e-03	178	53	3	de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH6 DNAH7 DNAH11	1.23e-03	178	53	3	3b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCell	15-Airway-Epithelial-Multiciliated_precursor\|Airway / Age, Tissue, Lineage and Cell class	DNAH6 DNAH7 DNAH11	1.23e-03	178	53	3	d8e0a696bdd6af6422d72af0413f9dbd6bc02afa
ToppCell	RV-11._Adipocyte\|RV / Chamber and Cluster_Paper	ROCK2 DOCK11 ABCD2	1.23e-03	178	53	3	278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCell	Ciliated_cells-A-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	DNAH6 DNAH7 DNAH11	1.23e-03	178	53	3	255473ee6df8a13079fb3bb61038162a40cb4c2c
ToppCell	FF-Differ-KC\|World / shred by cell class for mouse tongue	KCNAB1 IGDCC4 DNAH11	1.25e-03	179	53	3	1526a130565a97c291a25a7a988089bffc1515c1
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH6 DNAH7 DNAH11	1.25e-03	179	53	3	5e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCell	droplet-Tongue-Unstain-18m-Epithelial-suprabasal_interpapillary\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENDOD1 SLC10A6 ME1	1.27e-03	180	53	3	18bf8561ad3aa9787d2a8ef942a96f641734c608
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH6 DNAH7 DNAH11	1.27e-03	180	53	3	1f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCell	wk_15-18-Hematologic-Myeloid-APOE+_Mac2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	KCNAB1 ME1 MX1	1.27e-03	180	53	3	c630a121aedd09a51ea18cc6e8552eb979e5b555
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 DNAH7 DNAH11	1.29e-03	181	53	3	6a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-T_cells-Treg\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RESF1 CXCL13 DDX24	1.29e-03	181	53	3	a6c8b33a392de3df2f179317e329e45d3d8c6f52
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DNAH6 DNAH7 DNAH11	1.29e-03	181	53	3	dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCell	COVID-19_Mild-CD4+_T_activated\|COVID-19_Mild / Disease condition and Cell class	DST GCN1 MX1	1.31e-03	182	53	3	877b6e611626628e709568747512f2827ebb2795
ToppCell	Adult-Epithelial-ciliated_cell-D122\|Adult / Lineage, Cell type, age group and donor	DNAH6 DNAH7 DNAH11	1.31e-03	182	53	3	7ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCell	facs-Tongue-nan-24m-Epithelial-keratinocyte\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ALDH1L2 CXCL13 ME1	1.31e-03	182	53	3	41f1749e2368397bca49143786da0423792f03bd
ToppCell	Control-Epithelial_cells-Airway_ciliated\|Control / group, cell type (main and fine annotations)	DNAH6 DNAH7 DNAH11	1.31e-03	182	53	3	fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SETMAR LYPLAL1 RRS1	1.31e-03	182	53	3	9174fb0b7ed8f721a5c513e41fd80476a9f34332
ToppCell	Ciliated_cells-B-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	DNAH6 DNAH7 DNAH11	1.31e-03	182	53	3	e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ENDOD1 DST CXCL13	1.34e-03	183	53	3	547b1fb9f9940cfc8d6e351d96acc0da44def57e
ToppCell	LA-11._Adipocyte\|World / Chamber and Cluster_Paper	DOCK11 ABCD2 ME1	1.34e-03	183	53	3	b177be283e1553fb1f69a346f1ba79ad00297fa2
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK11 KCNAB1 IGDCC4	1.34e-03	183	53	3	121791ef84e7ce377ed6f5b7953af8865e04958e
ToppCell	LA-11._Adipocyte\|LA / Chamber and Cluster_Paper	DOCK11 ABCD2 ME1	1.34e-03	183	53	3	3f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCell	367C-Epithelial_cells-Epithelial-F_(Ciliated)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	DNAH6 DNAH7 DNAH11	1.34e-03	183	53	3	b1336eac5adbffade4cef3e0ce3de75a781ae365
ToppCell	367C-Epithelial_cells-Epithelial-F_(Ciliated)\|367C / Donor, Lineage, Cell class and subclass (all cells)	DNAH6 DNAH7 DNAH11	1.34e-03	183	53	3	cc57dcb59c68d68a546dc108dd9e009b2aab8da5
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 DNAH7 DNAH11	1.36e-03	184	53	3	da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_12\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ACAD11 ZFP28 ABCD2	1.36e-03	184	53	3	b8ecf58b3bdb25bcba5efc2d764930bb84ab95c8
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK11 KCNAB1 IGDCC4	1.36e-03	184	53	3	7d41784eac0935e77d6bc701f20c693adf998730
ToppCell	Ciliated_cells-A-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	DNAH6 DNAH7 DNAH11	1.36e-03	184	53	3	07c5a9633ccdcd18771e3230d6198a55c400afa6
ToppCell	(2)_5-FU-(4)_COL2.3+_osteoblasts\|World / Stress and Cell class	PEG3 ME1 IGDCC4	1.36e-03	184	53	3	684d05340a3dfb8aa08b881516a37f9627a10448
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_12\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ACAD11 ZFP28 ABCD2	1.36e-03	184	53	3	b232a9cc1d14e1a134b037016d437b93921a4a0f
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	DOCK11 SLC26A2 ALDH1L2	1.36e-03	184	53	3	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DNAH6 DNAH7 DNAH11	1.36e-03	184	53	3	5daff849625f2f41d56615569c0ed59cd733b34c
ToppCell	Adult-Epithelial-ciliated_cell-D175\|Adult / Lineage, Cell type, age group and donor	DNAH6 DNAH7 DNAH11	1.38e-03	185	53	3	30f4980dee6cd5959655f8d74049f3bfb5312611
Disease	Malignant mesothelioma	TRAF7 CXCL13 TFDP2	9.50e-04	109	52	3	C0345967
Disease	Alzheimer disease, polygenic risk score	SF3B3 DST RESF1 SUGT1 ABCD2	3.66e-03	586	52	5	EFO_0030082, MONDO_0004975

Protein segments in the cluster

Peptide	Gene	Start	Entry
VEKKPRTFIIKLIKW	ABCD2	136	Q9UBJ2
FKLPKWRVKGKTIKE	ALDH1L2	76	Q3SY69
KKEPAVLELEGKKWR	CAP1	316	Q01518
EKLPQEWKKKSLIQK	DNAH11	3866	Q96DT5
PETIKCLKKSNIKIW	ATP8B3	746	O60423
VVVKLLPEEHWKVVK	DIS3L2	111	Q8IYB7
KNVIKKKGEIIILWT	CASP8AP2	1916	Q9UKL3
SVDKWGKPLVIDKLK	ACAD11	411	Q709F0
ELIIGKKFKLPVWET	AIP	61	O00170
QAWDVGPVRLKKKVK	IGDCC4	686	Q8TDY8
IKQKRKEKAGKWEVP	NSA2	106	O95478
KEKAGKWEVPLPKVR	NSA2	111	O95478
IIVWEKKPTVEEKAK	RANBP2	2711	P49792
KVKIPEELKPWLVDD	MORF4L1	196	Q9UBU8
EKLIIWKIALSPITK	NUP133	121	Q8WUM0
EVVIPKKKTWDKVAV	PTCD3	56	Q96EY7
GLPKEKAIKKIWLVD	ME1	321	P48163
KAIKKIWLVDSKGLI	ME1	326	P48163
KLQEKWSLKTPEIQK	DST	4416	Q03001
KAEVILGSIIKKKGW	KCNAB1	146	Q14722
SIPWKVLKVVAKVIR	ENDOD1	396	O94919
VKKLTKLWKENPGLV	GCN1	166	Q92616
IWTIIPKKLGKVNIT	OVOS2	846	Q6IE36
LWLTKTKLIEGLPEK	MRPL37	121	Q9BZE1
PRKEIIVWKKNKSIV	CXCL13	61	O43927
TIIPEKLKPWVRAKK	PEG3	96	Q9GZU2
QKWITEEKPEVPDKK	DNAH6	481	Q9C0G6
KKIVWLKLLIPKITG	GSTT4	111	A0A1W2PR19
KVPRLKTWLLSEKKG	TMEM167B	26	Q9NRX6
IKWVDGAKPLLKIKS	DOCK11	801	Q5JSL3
KLKVKVKIGASWGEL	POLQ	2571	O75417
EGIGKWEPWIKKLKE	DNAH7	1921	Q8WXX0
LKLWILTKLPGEMEK	LYPLAL1	221	Q5VWZ2
KGIKVVGKWKEVKID	DDX24	21	Q9GZR7
IKNWKELPAVLEKEK	RXYLT1	386	Q9Y2B1
RIGVWATKPILKGKK	PRDM2	41	Q13029
DVKLKLKQSIEWPLK	SPATA5L1	471	Q9BVQ7
VKEKVGGKQPDKIWI	RESF1	1536	Q9HCM1
CGLVWVPIIKKKQKH	PIRT	106	P0C851
GKVKKLDKWVPHELT	SETMAR	451	Q53H47
GLTIKPLVKWLKVKR	SLC9A5	446	Q14940
LVKPEVWTLKEKCIL	PSME2	106	Q9UL46
KWVGVLSELHKILKK	CDC42BPA	1191	Q5VT25
IISKEKKEIKWIGLP	TFDP2	196	Q14188
IISKEKKEIKWIGLP	TFDP1	181	Q14186
LKAVWKIKELPLKKD	ZFP28	176	Q8NHY6
PILIKVAWKKAAKRK	SLC26A2	606	P50443
KPERKIQFKEKVLWT	SEC61A1	21	P61619
KGIRPKKKTNLVWDE	RRS1	121	Q15050
KVWDIVGTELKLKKE	TRAF7	501	Q6Q0C0
EQQKWVSRLVKKIPK	ROCK2	1336	O75116
WPKQSKIILKIGAVV	SLC10A6	186	Q3KNW5
KIEIKLKKPEAVRWE	SUGT1	241	Q9Y2Z0
KRVNEWKTPGKKTIV	SF3B3	531	Q15393
KKKALIIIWAKVLQP	GEMIN4	66	P57678
PLVLKLKKLVNEDKW	MX1	106	P20591