Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionactin binding

SHROOM4 SPATA31A1 SPATA31A3 SHROOM2 SPATA31A5 SPATA31A7

1.95e-04479366GO:0003779
GeneOntologyMolecularFunctionhistone methyltransferase binding

GATA3 PRDM4

4.75e-0418362GO:1990226
DomainDUF4599

SPATA31A3 SPATA31A5 SPATA31A7

1.31e-0612353PF15371
DomainDUF4599

SPATA31A3 SPATA31A5 SPATA31A7

1.31e-0612353IPR027970
DomainASD2

SHROOM4 SHROOM2

2.04e-054352PS51307
DomainASD2

SHROOM4 SHROOM2

2.04e-054352PF08687
DomainShroom_fam

SHROOM4 SHROOM2

2.04e-054352IPR027685
DomainASD2_dom

SHROOM4 SHROOM2

2.04e-054352IPR014799
DomainABC_membrane

ABCC8 ABCC10

9.18e-0424352PF00664
DomainABC_TM1F

ABCC8 ABCC10

1.25e-0328352PS50929
DomainABC1_TM_dom

ABCC8 ABCC10

1.25e-0328352IPR011527
DomainABC_transporter_CS

ABCC8 ABCC10

2.80e-0342352IPR017871
DomainABC_TRANSPORTER_2

ABCC8 ABCC10

3.65e-0348352PS50893
DomainABC_tran

ABCC8 ABCC10

3.65e-0348352PF00005
DomainABC_TRANSPORTER_1

ABCC8 ABCC10

3.80e-0349352PS00211
DomainABC_transporter-like

ABCC8 ABCC10

3.95e-0350352IPR003439
Pubmed

The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.

SPATA31A1 SPATA31A3 SPATA31A5 SPATA31A7

1.62e-11637420850414
Pubmed

Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.

SPATA31A1 SPATA31A3 SPATA31A5 SPATA31A7

1.62e-11637425930072
Pubmed

Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.

SPATA31A1 SPATA31A3 SPATA31A5 SPATA31A7

1.13e-082437432212159
Pubmed

GATA3 and MYB Expression in Cutaneous Adnexal Neoplasms.

GATA3 MYB

1.10e-06237228323779
Pubmed

The transcription factor c-Myb primes CD4+CD8+ immature thymocytes for selection into the iNKT lineage.

GATA3 MYB

3.30e-06337220383148
Pubmed

Architecture of a lymphomyeloid developmental switch controlled by PU.1, Notch and Gata3.

GATA3 MYB

6.60e-06437223444353
Pubmed

Differential actin-dependent localization modulates the evolutionarily conserved activity of Shroom family proteins.

SHROOM4 SHROOM2

6.60e-06437216684770
Pubmed

c-Myb and GATA-3 cooperatively regulate IL-13 expression via conserved GATA-3 response element and recruit mixed lineage leukemia (MLL) for histone modification of the IL-13 locus.

GATA3 MYB

6.60e-06437222039304
Pubmed

c-Myb regulates lineage choice in developing thymocytes via its target gene Gata3.

GATA3 MYB

6.60e-06437217641686
Pubmed

c-Myb, Menin, GATA-3, and MLL form a dynamic transcription complex that plays a pivotal role in human T helper type 2 cell development.

GATA3 MYB

6.60e-06437220484083
Pubmed

A new standard nomenclature for proteins related to Apx and Shroom.

SHROOM4 SHROOM2

6.60e-06437216615870
Pubmed

Variation at 3p24.1 and 6q23.3 influences the risk of Hodgkin's lymphoma.

GATA3 MYB

1.10e-05537224149102
Pubmed

Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins.

ZNF17 YTHDC1 UTP4

2.23e-055137311853319
Pubmed

Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions.

SHROOM4 SHROOM2

3.95e-05937217666436
Pubmed

Regulation of GATA-3 expression during CD4 lineage differentiation.

GATA3 MYB

4.93e-051037221357543
Pubmed

Tbx1 and Brn4 regulate retinoic acid metabolic genes during cochlear morphogenesis.

GATA3 POU3F4

1.31e-041637219476657
Pubmed

Reciprocal interactions of Pit1 and GATA2 mediate signaling gradient-induced determination of pituitary cell types.

GATA3 POU3F4

2.28e-042137210367888
Pubmed

Jak2 is essential for signaling through a variety of cytokine receptors.

GATA3 MYB

2.28e-04213729590173
Pubmed

Identification of 18 mouse ABC genes and characterization of the ABC superfamily in Mus musculus.

ABCC8 ABCC10

2.75e-042337210708515
Pubmed

β-Cell-Specific Mafk Overexpression Impairs Pancreatic Endocrine Cell Development.

POU3F4 ABCC8

6.78e-043637226901059
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

JARID2 HRG MAP7D1 TRAPPC5

8.12e-0439637426687479
CytobandEnsembl 112 genes in cytogenetic band chr9q12

SPATA31A5 SPATA31A7

1.76e-058372chr9q12
Cytoband9p13.1

SPATA31A1 SPATA31A3

1.72e-04243729p13.1
GeneFamilyATP binding cassette subfamily C

ABCC8 ABCC10

1.31e-0413242807
GeneFamilyActins|Deafness associated genes

POU3F4 PTPRQ

9.77e-031132421152
GeneFamilyPDZ domain containing

SHROOM4 SHROOM2

1.72e-021522421220
CoexpressionAtlasgamma delta T cells, Tgd.vg2-.Sp, TCRd+ Vg2- CD44-, Spleen, avg-3

GATA3 NKG7 MYB

2.98e-0479353GSM476684_100
CoexpressionAtlasgamma delta T cells, Tgd.vg2-.Sp.TCRbko, TCRd+ Vg2- CD44-, Spleen, avg-3

GATA3 NKG7 MYB

3.32e-0482353GSM605796_100
CoexpressionAtlasalpha beta T cells, preT.DN2-3.Th, Lin-/lo CD25hi CD44Int, Thymus, avg-2

GATA3 NKG7 MYB

3.44e-0483353GSM791134_100
CoexpressionAtlasgamma delta T cells, Tgd.Th, TCRd+ CD3e+, Thymus, avg-3

GATA3 NKG7 MYB

3.57e-0484353GSM476675_100
CoexpressionAtlasalpha beta T cells, preT.DN2A.Th, Lin-/lo CD25hi CD44+ cKithi, Thymus, avg-2

GATA3 NKG7 MYB

3.57e-0484353GSM791139_100
CoexpressionAtlasgamma delta T cells, Tgd.vg2+24ahi.Th.TCRbko, TCRd+ Vg2+ CD24+, Thymus, avg-3

GATA3 NKG7 MYB

3.69e-0485353GSM605793_100
CoexpressionAtlasalpha beta T cells, preT.DN2.Th, Lin-/lo CD25hi CD44+ cKit+, Thymus, avg-3

GATA3 NKG7 MYB

3.69e-0485353GSM791136_100
CoexpressionAtlasgamma delta T cells, Tgd.vg2+24ahi.Th, TCRd+ Vg2+ CD24+, Thymus, avg-3

GATA3 NKG7 MYB

3.95e-0487353GSM476655_100
CoexpressionAtlasgamma delta T cells, Tgd.vg2-24ahi.Th, TCRd+ Vg2- CD24+, Thymus, avg-2

GATA3 NKG7 MYB

3.95e-0487353GSM476658_100
CoexpressionAtlasalpha beta T cells, preT.DN3A.Th, Lin-/lo CD25hi CD44- CD28-, Thymus, avg-3

GATA3 NKG7 MYB

4.23e-0489353GSM791146_100
CoexpressionAtlasgamma delta T cells, Tgd.vg2+24ahi.e17.Th, TCRd+ Vg2+ CD24+, Fetal Thymus, avg-3

GATA3 NKG7 MYB

4.23e-0489353GSM476660_100
CoexpressionAtlasalpha beta T cells, preT.DN2B.Th, Lin-/lo CD25hi CD44+ cKitint, Thymus, avg-2

GATA3 NKG7 MYB

4.66e-0492353GSM791141_100
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHROOM4 MYB PTPRQ CEMIP

9.06e-061593747619d0d49738dd08daf01b42664691a5323aa793
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHROOM4 MYB PTPRQ CEMIP

9.06e-061593744000ed0d3b7d488722bcd0042fa2ff4405aaab82
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SHROOM4 MYB PTPRQ CEMIP

1.07e-051663745e3b998d740b24f790fad37350d704ca0ea10b77
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SHROOM4 MYB PTPRQ CEMIP

1.07e-05166374bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCellcellseq2-Mesenchymal-Myocytic-Myocytic_1-Pericyte|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

AFF2 SHROOM2 DAGLA FAM110B

1.38e-0517737468263456a3c93cd195b321b309ff59e156d732fe
ToppCellcellseq2-Mesenchymal-Myocytic-Myocytic_1|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

AFF2 SHROOM2 DAGLA FAM110B

1.38e-05177374e415e448c37adc102d766235e9953dec32c021f1
Diseasecardiovascular disease

DCLRE1B ABCC10 MYB FAM110B

1.63e-03457334EFO_0000319
DiseaseNonsyndromic genetic hearing loss

POU3F4 PTPRQ

3.28e-0376332cv:C5680182
DiseaseNonsyndromic Deafness

POU3F4 CEMIP

3.72e-0381332C3711374
DiseaseMalignant neoplasm of breast

MTMR3 GATA3 HRG SHROOM2 NUDT2

6.44e-031074335C0006142

Protein segments in the cluster

PeptideGeneStartEntry
HSWPTPLTSMHTAGH

AFF2

366

P51816
ASDGIHHWTPPKGHV

NUDT2

31

P50583
WMGHGSPLSHSSKGT

DCLRE1B

476

Q9H816
GSKHFLHLGFRHPWS

CEMIP

256

Q8WUJ3
SGHHGAWHISLSKPS

PODXL2

426

Q9NZ53
SLALWVLAHSPHGHS

ABCC10

116

Q5T3U5
HTHLHAGSTKSAPGA

FOXB2

116

Q5VYV0
HPFHWGGHERSSTTK

HRG

261

P04196
GWHSTTIADHTRPHG

MYB

326

P10242
EHGLWAIHSGPGTHS

OLFML1

276

Q6UWY5
HPLGHHWVTSLSDGG

POU3F4

51

P49335
THSFSLHWSLPSGHV

PTPRQ

21

Q9UMZ3
HGHGWQHSLLGPILS

PARP16

196

Q8N5Y8
WLDGGKALGSHHTAS

GATA3

96

P23771
HSHWGPHAKGQCASR

GIMAP2

6

Q9UG22
AHKLSGLWNSPHSSG

FAM193B

201

Q96PV7
STHRIPWSLASHGHT

GAB4

286

Q2WGN9
WSWAGALHHSSPGHK

MAP7D1

231

Q3KQU3
GHHGTWLGHKGMVLS

DAGLA

421

Q9Y4D2
SSSGSGHKHSSRNWP

FAM110B

131

Q8TC76
FSPDSHHHDHWFSPG

GPATCH2

381

Q9NW75
HSAHSGLWPTGHGDI

NKG7

36

Q16617
HKWLHSHSGRPSATS

MTMR3

991

Q13615
HSGSHGPSHSKERKW

PRDM4

576

Q9UKN5
TGSSAKGLAATHHHP

JARID2

276

Q92833
LSWHPSGTHIAAGSI

UTP4

151

Q969X6
PQHWPKTSGASSHHH

SPATA31A7

1321

Q8IWB4
PSWSGRHHASSSSHD

SHROOM2

141

Q13796
DGHQWTLSPLHSSHK

SHROOM4

441

Q9ULL8
SKVHIHHSTWLHFPG

ABCC8

56

Q09428
PQHWPKTSGASSHHH

SPATA31A3

1321

Q5VYP0
LQHWPKTSGASSHHH

SPATA31A1

1321

Q5TZJ5
PQHWPKTSGASSHHH

SPATA31A5

1321

Q5VU36
GHTAMLHTGSWHPKI

WDR70

281

Q9NW82
SSESHHGGSPIHWVL

YTHDC1

416

Q96MU7
ALHSGWKPHRDTHGV

ZNF17

166

P17021
LTHSGFPAKVTAHWH

TRAPPC5

151

Q8IUR0