Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

CHRNA9 GRIN2A GRIN2B GRM5 GLRA2

1.72e-04751385GO:0098960
GeneOntologyMolecularFunctionexcitatory extracellular ligand-gated monoatomic ion channel activity

CHRNA9 GRIN2A GRIN2B GLRA2

2.19e-04431384GO:0005231
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH2 DNAH17 DNAH8

2.44e-04181383GO:0008569
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration

GRIN2B GRM5

2.82e-0441382GO:0099583
GeneOntologyMolecularFunctionalpha-1,4-glucosidase activity

MGAM SI

4.68e-0451382GO:0004558
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

CHRNA9 GRIN2A GRIN2B GLRA2

6.49e-04571384GO:1904315
GeneOntologyMolecularFunctionneurotransmitter receptor activity

CHRNA9 GRIN2A GRIN2B GRM5 GLRA2

6.52e-041001385GO:0030594
GeneOntologyMolecularFunctionprotein kinase A regulatory subunit binding

AKAP6 RYR2 AKAP1

6.65e-04251383GO:0034237
GeneOntologyMolecularFunctionsingle-stranded DNA 3'-5' DNA exonuclease activity

POLE POLG

6.98e-0461382GO:0008310
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

CHRNA9 GRIN2A GRIN2B GLRA2

7.89e-04601384GO:0099529
GeneOntologyMolecularFunctionfibroblast growth factor binding

SCN5A FIBP KLB

8.37e-04271383GO:0017134
GeneOntologyMolecularFunctionglutamate receptor activity

GRIN2A GRIN2B GRM5

8.37e-04271383GO:0008066
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH2 DNAH17 DNAH8

9.32e-04281383GO:0051959
GeneOntologyMolecularFunctionextracellularly glutamate-gated ion channel activity

GRIN2A GRIN2B

9.73e-0471382GO:0005234
GeneOntologyMolecularFunctionalpha-glucosidase activity

MGAM SI

9.73e-0471382GO:0090599
GeneOntologyMolecularFunctiontransmitter-gated channel activity

CHRNA9 GRIN2A GRIN2B GLRA2

1.07e-03651384GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

CHRNA9 GRIN2A GRIN2B GLRA2

1.07e-03651384GO:0022824
GeneOntologyMolecularFunctionligand-gated calcium channel activity

GRIN2A GRIN2B RYR2

1.26e-03311383GO:0099604
GeneOntologyMolecularFunctionglutamate-gated calcium ion channel activity

GRIN2A GRIN2B

1.29e-0381382GO:0022849
GeneOntologyMolecularFunctionadenosine receptor binding

GRM5 USP4

1.29e-0381382GO:0031685
GeneOntologyMolecularFunctionhistone H3K9 monomethyltransferase activity

SETDB1 SETDB2

1.29e-0381382GO:0140948
GeneOntologyMolecularFunctionNMDA glutamate receptor activity

GRIN2A GRIN2B

1.29e-0381382GO:0004972
GeneOntologyMolecularFunctionbeta-catenin binding

GRIN2B GRIP1 DCHS1 CDH3 CDH11

1.48e-031201385GO:0008013
GeneOntologyMolecularFunctionamino acid binding

CAD GRIN2A GRIN2B GLRA2

1.64e-03731384GO:0016597
GeneOntologyMolecularFunctionanaphase-promoting complex binding

CDC20B CDC20

1.65e-0391382GO:0010997
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

CHRNA9 GRIN2A GRIN2B GLRA2

2.00e-03771384GO:0005230
GeneOntologyMolecularFunctionhistone H3K9me2 methyltransferase activity

SETDB1 SETDB2

2.06e-03101382GO:0140947
GeneOntologyMolecularFunctionsingle-stranded DNA exodeoxyribonuclease activity

POLE POLG

2.06e-03101382GO:0008297
GeneOntologyMolecularFunctionubiquitin ligase activator activity

CDC20B CDC20

2.06e-03101382GO:1990757
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH2 DNAH17 DNAH8

2.11e-03371383GO:0045505
GeneOntologyMolecularFunctionDNA polymerase activity

SGIP1 POLE POLG

2.28e-03381383GO:0034061
GeneOntologyMolecularFunctionglutamate receptor binding

GRIN2A GRIN2B NEDD4 GRIP1

2.41e-03811384GO:0035254
GeneOntologyMolecularFunctioncell adhesion molecule binding

ADGRL1 GRIN2A GRIN2B DBN1 DSCAML1 TENM3 PTPRO DCHS1 PLEC CDH3 CDH11

3.00e-0359913811GO:0050839
GeneOntologyBiologicalProcessheart development

AKAP6 ERBB2 CAD IFT172 ZDHHC16 PCDHA10 NEB RYR2 NEDD4 SETDB2 ADAMTS6 SCN5A ALPK3 DCHS1 LRP2 MMP2 PLEC CDH11

2.52e-0675713618GO:0007507
GeneOntologyBiologicalProcesscell junction organization

ERBB2 RELN MYOC ADGRL1 GRIN2A GRIN2B DBN1 GRM5 NEDD4 TENM3 CAMKV PTPRO ARC LRP5 PLEC CDC20 CDH3 TNS1 CDH11 PLXNB1

6.12e-0697413620GO:0034330
GeneOntologyBiologicalProcessprotein-containing complex localization

AKAP6 ERBB2 RELN IFT172 GRIN2A DBN1 NEDD4 GRIP1 ARC NME7

1.61e-0527813610GO:0031503
GeneOntologyBiologicalProcessregulation of postsynaptic membrane potential

DPP6 RELN CHRNA9 GRIN2A GRIN2B DBN1 GRM5 GLRA2

2.62e-051801368GO:0060078
GeneOntologyBiologicalProcesspositive regulation of synapse maturation

RELN ADGRL1 CDC20

3.25e-05101363GO:0090129
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

DSG3 PCDHA11 PCDHA10 DSCAML1 TENM3 DCHS1 CDH3 CDH11

3.44e-051871368GO:0007156
GeneOntologyBiologicalProcesssynapse organization

ERBB2 RELN ADGRL1 GRIN2A GRIN2B DBN1 GRM5 NEDD4 TENM3 CAMKV PTPRO ARC LRP5 CDC20 PLXNB1

4.75e-0568513615GO:0050808
GeneOntologyBiologicalProcessmodulation of inhibitory postsynaptic potential

GRIN2A GRIN2B DBN1

5.91e-05121363GO:0098828
GeneOntologyBiologicalProcessregulation of membrane potential

AKAP6 DPP6 RELN CHRNA9 MYOC GRIN2A GRIN2B DBN1 GRM5 RYR2 NEDD4 GLRA2 SCN5A

8.56e-0555913613GO:0042391
GeneOntologyBiologicalProcessmodulation of chemical synaptic transmission

RELN PDE4A LAMA2 GRIN2A GRIN2B DBN1 GRM5 NEDD4 GRIP1 CAMKV GLRA2 ARC CDC20 CDH11

1.26e-0466313614GO:0050804
GeneOntologyBiologicalProcessregulation of trans-synaptic signaling

RELN PDE4A LAMA2 GRIN2A GRIN2B DBN1 GRM5 NEDD4 GRIP1 CAMKV GLRA2 ARC CDC20 CDH11

1.28e-0466413614GO:0099177
GeneOntologyBiologicalProcessDNA replication proofreading

POLE POLG

1.29e-0431362GO:0045004
GeneOntologyBiologicalProcesspositive regulation of anaphase-promoting complex-dependent catabolic process

CDC20B CDC20

1.29e-0431362GO:1905786
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

DMXL2 RELN PDE4A CHRNA9 LAMA2 GRIN2A GRIN2B DBN1 GRM5 NEDD4 GRIP1 SLC12A4 CAMKV GLRA2 ARC CDC20 CDH11

1.37e-0493113617GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

DMXL2 RELN PDE4A CHRNA9 LAMA2 GRIN2A GRIN2B DBN1 GRM5 NEDD4 GRIP1 SLC12A4 CAMKV GLRA2 ARC CDC20 CDH11

1.37e-0493113617GO:0007268
GeneOntologyBiologicalProcessaxonemal dynein complex assembly

DNAH2 DNAAF2 DNAH17 DNAH8

1.52e-04411364GO:0070286
GeneOntologyBiologicalProcesstrans-synaptic signaling

DMXL2 RELN PDE4A CHRNA9 LAMA2 GRIN2A GRIN2B DBN1 GRM5 NEDD4 GRIP1 SLC12A4 CAMKV GLRA2 ARC CDC20 CDH11

1.52e-0493913617GO:0099537
GeneOntologyBiologicalProcessdevelopmental maturation

RELN MYOC ADGRL1 TDRD1 ADAMTS12 BSPH1 DCHS1 MMP2 CDC20 CDH3 PLXNB1

1.61e-0443913611GO:0021700
GeneOntologyBiologicalProcessembryo development

CHRNA9 IFT172 POLE INPP5K LAMA2 GRIN2B DBN1 ECSIT TDRD1 LRP1B DSCAML1 RYR2 DNAAF2 SETDB1 SETDB2 CDC40 EIF2S2 DCHS1 LRP2 LRP5 DMBT1 FUT8

1.77e-04143713622GO:0009790
GeneOntologyBiologicalProcesspositive regulation of excitatory postsynaptic potential

RELN GRIN2A GRIN2B DBN1

1.83e-04431364GO:2000463
GeneOntologyBiologicalProcessregulation of neuronal synaptic plasticity

GRIN2A GRIN2B DBN1 GRM5 ARC

2.23e-04831365GO:0048168
GeneOntologyBiologicalProcessexcitatory postsynaptic potential

RELN CHRNA9 GRIN2A GRIN2B DBN1 GLRA2

2.25e-041301366GO:0060079
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

DSG3 PCDHA11 PCDHA10 ADGRL1 DSCAML1 TENM3 DCHS1 CDH3 CDH11

2.36e-043131369GO:0098742
GeneOntologyBiologicalProcesssynaptic signaling

DMXL2 RELN PDE4A CHRNA9 LAMA2 GRIN2A GRIN2B DBN1 GRM5 NEDD4 GRIP1 SLC12A4 CAMKV GLRA2 ARC CDC20 CDH11

2.39e-0497613617GO:0099536
GeneOntologyBiologicalProcessdisaccharide catabolic process

MGAM SI

2.57e-0441362GO:0046352
GeneOntologyBiologicalProcessregulation of actin filament-based movement

AKAP6 DBN1 RYR2 SCN5A

4.12e-04531364GO:1903115
GeneOntologyBiologicalProcessN-glycan fucosylation

FUT10 FUT8

4.26e-0451362GO:0036071
GeneOntologyBiologicalProcesspositive regulation of AMPA receptor activity

RELN ARC

4.26e-0451362GO:2000969
GeneOntologyBiologicalProcessregulation of anaphase-promoting complex-dependent catabolic process

CDC20B CDC20

4.26e-0451362GO:1905784
GeneOntologyBiologicalProcesschemical synaptic transmission, postsynaptic

RELN CHRNA9 GRIN2A GRIN2B DBN1 GLRA2

4.35e-041471366GO:0099565
GeneOntologyBiologicalProcessregulation of protein kinase A signaling

AKAP6 PDE4A GRIN2B

4.51e-04231363GO:0010738
GeneOntologyBiologicalProcessSchwann cell differentiation

ERBB2 MYOC LAMA2 PLEC

4.75e-04551364GO:0014037
GeneOntologyBiologicalProcessouter dynein arm assembly

DNAAF2 DNAH17 DNAH8

5.13e-04241363GO:0036158
GeneOntologyBiologicalProcessanaphase-promoting complex-dependent catabolic process

CDC20B ANAPC1 CDC20

5.80e-04251363GO:0031145
GeneOntologyBiologicalProcessinduction of bacterial agglutination

SPON2 DMBT1

6.36e-0461362GO:0043152
GeneOntologyBiologicalProcessPurkinje myocyte to ventricular cardiac muscle cell communication

RYR2 SCN5A

6.36e-0461362GO:0086068
GeneOntologyBiologicalProcessPurkinje myocyte to ventricular cardiac muscle cell signaling

RYR2 SCN5A

6.36e-0461362GO:0086029
GeneOntologyCellularComponentanaphase-promoting complex

CDC20B ANAPC1 BUB1B CDC20

1.46e-05231384GO:0005680
GeneOntologyCellularComponentdendritic spine

LAMA2 GRIN2A GRIN2B DBN1 GRM5 NEDD4 GRIP1 PTPRO ARC

3.38e-052421389GO:0043197
GeneOntologyCellularComponentneuron spine

LAMA2 GRIN2A GRIN2B DBN1 GRM5 NEDD4 GRIP1 PTPRO ARC

3.96e-052471389GO:0044309
GeneOntologyCellularComponentpostsynaptic membrane

ERBB2 CHRNA9 GRIN2A GRIN2B DBN1 GRM5 GRIP1 PTPRO GLRA2 ARC AKAP1

8.03e-0540513811GO:0045211
GeneOntologyCellularComponentRAVE complex

DMXL2 DMXL1

1.29e-0431382GO:0043291
GeneOntologyCellularComponentsynaptic membrane

ERBB2 CHRNA9 ADGRL1 GRIN2A GRIN2B DBN1 GRM5 GRIP1 TENM3 PTPRO GLRA2 ARC AKAP1

1.32e-0458313813GO:0097060
GeneOntologyCellularComponentmitotic checkpoint complex

BUB1B CDC20

2.57e-0441382GO:0033597
GeneOntologyCellularComponentaxon

RELN CAD MYOC POLG ADGRL1 GRIN2A GRIN2B DBN1 DSCAML1 TRAK1 GRIP1 TENM3 PTPRO SCN5A LRP2 PLEC

2.68e-0489113816GO:0030424
GeneOntologyCellularComponentnuclear ubiquitin ligase complex

CDC20B ANAPC1 BUB1B CDC20

3.06e-04491384GO:0000152
GeneOntologyCellularComponentpostsynaptic specialization membrane

CHRNA9 GRIN2A GRIN2B GRM5 PTPRO GLRA2 ARC

3.84e-042011387GO:0099634
GeneOntologyCellularComponentterminal bouton

CAD POLG GRIN2A GRIN2B GRIP1

4.40e-04961385GO:0043195
GeneOntologyCellularComponentdynein complex

DNAH2 NUDCD3 DNAH17 DNAH8

4.45e-04541384GO:0030286
GeneOntologyCellularComponentpostsynaptic specialization

CHRNA9 GRIN2A GRIN2B DBN1 GRM5 HNRNPA2B1 GRIP1 PTPRO GLRA2 ARC AKAP1

5.18e-0450313811GO:0099572
GeneOntologyCellularComponentaxonemal dynein complex

DNAH2 DNAH17 DNAH8

5.82e-04251383GO:0005858
GeneOntologyCellularComponentdistal axon

CAD POLG ADGRL1 GRIN2A GRIN2B DBN1 TRAK1 GRIP1 PTPRO LRP2

6.36e-0443513810GO:0150034
GeneOntologyCellularComponentmonoatomic ion channel complex

AKAP6 DPP6 CHRNA9 GRIN2A GRIN2B RYR2 GLRA2 SCN5A CATSPERG

9.30e-043781389GO:0034702
GeneOntologyCellularComponentU2-type catalytic step 2 spliceosome

CRNKL1 CDC40 PRPF19

1.11e-03311383GO:0071007
GeneOntologyCellularComponentcatenin complex

DCHS1 CDH3 CDH11

1.21e-03321383GO:0016342
GeneOntologyCellularComponentsomatodendritic compartment

DPP6 RELN CAD ENC1 LAMA2 GRIN2A GRIN2B DBN1 GRM5 CPNE5 HNRNPA2B1 TRAK1 NEDD4 GRIP1 PTPRO LRP2 ARC PLEC

1.22e-03122813818GO:0036477
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

IFT172 DNAH2 HNRNPA2B1 TRAK1 DNAH17 ARC NME7 DNAH8

1.24e-033171388GO:0032838
GeneOntologyCellularComponentsynaptic cleft

LAMA2 GRIN2B GRIP1

1.33e-03331383GO:0043083
GeneOntologyCellularComponentNMDA selective glutamate receptor complex

GRIN2A GRIN2B

1.51e-0391382GO:0017146
GeneOntologyCellularComponentneuronal ribonucleoprotein granule

HNRNPA2B1 ARC

1.88e-03101382GO:0071598
GeneOntologyCellularComponentjunctional sarcoplasmic reticulum membrane

AKAP6 RYR2

1.88e-03101382GO:0014701
GeneOntologyCellularComponentplasma membrane protein complex

DPP6 ERBB2 SGIP1 CHRNA9 GRIN2A GRIN2B SCN5A DCHS1 LRP5 C8A CATSPERG CDH3 CDH11

2.11e-0378513813GO:0098797
GeneOntologyCellularComponentcytoplasmic region

IFT172 DNAH2 HNRNPA2B1 TRAK1 DNAH17 ARC NME7 DNAH8

2.73e-033601388GO:0099568
GeneOntologyCellularComponentouter dynein arm

DNAH17 DNAH8

2.73e-03121382GO:0036157
GeneOntologyCellularComponentcullin-RING ubiquitin ligase complex

ENC1 CDC20B KBTBD7 ANAPC1 BUB1B CDC20

2.87e-032121386GO:0031461
GeneOntologyCellularComponentglutamatergic synapse

ADGRL1 GRIN2A GRIN2B DBN1 GRM5 HNRNPA2B1 NEDD4 GRIP1 TENM3 CAMKV PTPRO ARC CDH11

2.98e-0381713813GO:0098978
GeneOntologyCellularComponentpostsynapse

ERBB2 CHRNA9 LAMA2 GRIN2A GRIN2B DBN1 GRM5 HNRNPA2B1 NEDD4 GRIP1 CAMKV PTPRO GLRA2 ARC AKAP1

3.00e-03101813815GO:0098794
GeneOntologyCellularComponentsemaphorin receptor complex

ERBB2 PLXNB1

3.22e-03131382GO:0002116
GeneOntologyCellularComponentpostsynaptic cytosol

DBN1 HNRNPA2B1 NEDD4

3.26e-03451383GO:0099524
GeneOntologyCellularComponentaxonal growth cone

DBN1 TRAK1 LRP2

3.26e-03451383GO:0044295
GeneOntologyCellularComponentZ disc

GRIN2B NEB RYR2 SCN5A PLEC

3.30e-031511385GO:0030018
GeneOntologyCellularComponentbrush border

RALGDS ANPEP SI LRP2 PLEC

3.40e-031521385GO:0005903
GeneOntologyCellularComponentpostsynaptic density membrane

GRIN2A GRIN2B GRM5 PTPRO ARC

3.90e-031571385GO:0098839
GeneOntologyCellularComponentcatalytic step 2 spliceosome

HNRNPA2B1 CRNKL1 CDC40 PRPF19

3.92e-03971384GO:0071013
GeneOntologyCellularComponentdendrite

RELN LAMA2 GRIN2A GRIN2B DBN1 GRM5 TRAK1 NEDD4 GRIP1 PTPRO LRP2 ARC PLEC

4.50e-0385813813GO:0030425
GeneOntologyCellularComponentdendritic tree

RELN LAMA2 GRIN2A GRIN2B DBN1 GRM5 TRAK1 NEDD4 GRIP1 PTPRO LRP2 ARC PLEC

4.59e-0386013813GO:0097447
GeneOntologyCellularComponentPrp19 complex

CRNKL1 PRPF19

4.89e-03161382GO:0000974
GeneOntologyCellularComponentI band

GRIN2B NEB RYR2 SCN5A PLEC

4.94e-031661385GO:0031674
Domain-

NHLRC3 LRP1B TENM3 TRIM56 LRP2 LRP5

3.27e-073913462.120.10.30
Domain6-blade_b-propeller_TolB-like

NHLRC3 LRP1B TENM3 TRIM56 LRP2 LRP5

9.02e-07461346IPR011042
DomainWD40

DMXL2 IFT172 CDC20B NUP214 EML3 DMXL1 CDC40 WDR97 PRPF19 CDC20

2.39e-0526813410SM00320
DomainWD40_repeat

DMXL2 IFT172 CDC20B NUP214 EML3 DMXL1 CDC40 WDR97 PRPF19 CDC20

2.72e-0527213410IPR001680
Domain-

DMXL2 IFT172 CDC20B NUP214 EML3 DMXL1 CDC40 WDR97 PRPF19 CDC20 PLXNB1

2.87e-05333134112.130.10.10
DomainWD40/YVTN_repeat-like_dom

DMXL2 IFT172 CDC20B NUP214 EML3 DMXL1 CDC40 WDR97 PRPF19 CDC20 PLXNB1

3.03e-0533513411IPR015943
DomainRav1p_C

DMXL2 DMXL1

5.11e-0521342IPR022033
DomainRav1p_C

DMXL2 DMXL1

5.11e-0521342PF12234
DomainWD40_repeat_dom

DMXL2 IFT172 CDC20B EML3 DMXL1 CDC40 TENM3 WDR97 PRPF19 CDC20

5.71e-0529713410IPR017986
DomainWD40

DMXL2 IFT172 CDC20B EML3 DMXL1 CDC40 WDR97 PRPF19 CDC20

1.07e-042591349PF00400
DomainLdl_recept_b

LRP1B LRP2 LRP5

1.24e-04141343PF00058
DomainLDLRB

LRP1B LRP2 LRP5

1.24e-04141343PS51120
DomainCadherin_CS

DSG3 PCDHA11 PCDHA10 DCHS1 CDH3 CDH11

1.35e-041091346IPR020894
DomainCdc20/Fizzy

CDC20B CDC20

1.53e-0431342IPR033010
DomainNMDAR2_C

GRIN2A GRIN2B

1.53e-0431342PF10565
DomainNMDAR2_C

GRIN2A GRIN2B

1.53e-0431342IPR018884
DomainLY

LRP1B LRP2 LRP5

1.54e-04151343SM00135
DomainLDLR_classB_rpt

LRP1B LRP2 LRP5

1.54e-04151343IPR000033
DomainCADHERIN_1

DSG3 PCDHA11 PCDHA10 DCHS1 CDH3 CDH11

1.64e-041131346PS00232
DomainCadherin

DSG3 PCDHA11 PCDHA10 DCHS1 CDH3 CDH11

1.64e-041131346PF00028
DomainCADHERIN_2

DSG3 PCDHA11 PCDHA10 DCHS1 CDH3 CDH11

1.72e-041141346PS50268
Domain-

DSG3 PCDHA11 PCDHA10 DCHS1 CDH3 CDH11

1.72e-0411413462.60.40.60
DomainCA

DSG3 PCDHA11 PCDHA10 DCHS1 CDH3 CDH11

1.81e-041151346SM00112
DomainWD_REPEATS_1

DMXL2 IFT172 CDC20B EML3 DMXL1 CDC40 WDR97 PRPF19 CDC20

1.82e-042781349PS00678
DomainWD_REPEATS_2

DMXL2 IFT172 CDC20B EML3 DMXL1 CDC40 WDR97 PRPF19 CDC20

1.87e-042791349PS50082
DomainWD_REPEATS_REGION

DMXL2 IFT172 CDC20B EML3 DMXL1 CDC40 WDR97 PRPF19 CDC20

1.87e-042791349PS50294
DomainLDLR_class-A_CS

LRP1B LRP2 LRP5 C8A

1.89e-04401344IPR023415
DomainCadherin-like

DSG3 PCDHA11 PCDHA10 DCHS1 CDH3 CDH11

1.90e-041161346IPR015919
DomainCadherin

DSG3 PCDHA11 PCDHA10 DCHS1 CDH3 CDH11

2.08e-041181346IPR002126
DomainLdl_recept_a

LRP1B LRP2 LRP5 C8A

3.00e-04451344PF00057
DomainGlyco_hydro_31_CS

MGAM SI

3.04e-0441342IPR030459
DomainGal_mutarotase_N

MGAM SI

3.04e-0441342IPR031727
DomainNtCtMGAM_N

MGAM SI

3.04e-0441342PF16863
Domain-

LRP1B LRP2 LRP5 C8A

3.27e-044613444.10.400.10
DomainLDLRA_1

LRP1B LRP2 LRP5 C8A

3.86e-04481344PS01209
DomainLDrepeatLR_classA_rpt

LRP1B LRP2 LRP5 C8A

4.18e-04491344IPR002172
DomainLDLa

LRP1B LRP2 LRP5 C8A

4.18e-04491344SM00192
DomainLDLRA_2

LRP1B LRP2 LRP5 C8A

4.18e-04491344PS50068
DomainGLYCOSYL_HYDROL_F31_2

MGAM SI

5.04e-0451342PS00707
DomainTUDOR

TDRD1 SETDB1 AKAP1

5.76e-04231343PS50304
DomainCadherin_C

DSG3 CDH3 CDH11

7.40e-04251343PF01049
DomainCadherin_cytoplasmic-dom

DSG3 CDH3 CDH11

7.40e-04251343IPR000233
DomainGlyco_hydro_31_AS

MGAM SI

7.52e-0461342IPR030458
DomainEGF_extracell

RELN LRP1B TENM3 LRP2

9.05e-04601344IPR013111
DomainEGF_2

RELN LRP1B TENM3 LRP2

9.05e-04601344PF07974
DomainTUDOR

TDRD1 SETDB1 AKAP1

9.31e-04271343SM00333
DomainGlyco_hydro_31

MGAM SI

1.05e-0371342IPR000322
DomainPre-SET

SETDB1 SETDB2

1.05e-0371342PF05033
DomainGlyco_hydro_31

MGAM SI

1.05e-0371342PF01055
DomainPreSET

SETDB1 SETDB2

1.05e-0371342SM00468
DomainPre-SET_dom

SETDB1 SETDB2

1.05e-0371342IPR007728
DomainGLYCOSYL_HYDROL_F31_1

MGAM SI

1.05e-0371342PS00129
DomainPRE_SET

SETDB1 SETDB2

1.05e-0371342PS50867
DomainTSP_1

ADAMTS12 ADAMTS6 SPON2 C8A

1.09e-03631344PF00090
DomainCatenin_binding_dom

DSG3 CDH3 CDH11

1.15e-03291343IPR027397
Domain-

DSG3 CDH3 CDH11

1.15e-032913434.10.900.10
DomainTSP1

ADAMTS12 ADAMTS6 SPON2 C8A

1.22e-03651344SM00209
DomainTSP1_rpt

ADAMTS12 ADAMTS6 SPON2 C8A

1.22e-03651344IPR000884
DomainTSP1

ADAMTS12 ADAMTS6 SPON2 C8A

1.22e-03651344PS50092
DomainTudor

TDRD1 SETDB1 AKAP1

1.27e-03301343IPR002999
DomainDHC_N1

DNAH2 DNAH8

1.39e-0381342PF08385
DomainP_TREFOIL_1

MGAM SI

1.39e-0381342PS00025
DomainTrefoil

MGAM SI

1.39e-0381342PF00088
DomainP_trefoil_CS

MGAM SI

1.39e-0381342IPR017957
DomainDynein_heavy_dom-1

DNAH2 DNAH8

1.39e-0381342IPR013594
DomainP_TREFOIL_2

MGAM SI

1.78e-0391342PS51448
DomainPD

MGAM SI

1.78e-0391342SM00018
DomainEGF-like_dom

RELN LAMA2 LRP1B TENM3 LRP2 LRP5 C8A

2.15e-032491347IPR000742
DomainNHL_repeat

NHLRC3 LRP1B

2.21e-03101342IPR001258
DomainNHL

NHLRC3 LRP1B

2.21e-03101342PF01436
DomainANF_lig-bd_rcpt

GRIN2A GRIN2B GRM5

2.35e-03371343IPR001828
DomainANF_receptor

GRIN2A GRIN2B GRM5

2.35e-03371343PF01094
DomainEGF_1

RELN LAMA2 LRP1B TENM3 LRP2 LRP5 C8A

2.46e-032551347PS00022
Domain-

MGAM SI

2.69e-031113424.10.110.10
DomainMBD

SETDB1 SETDB2

2.69e-03111342SM00391
DomainMBD

SETDB1 SETDB2

2.69e-03111342PS50982
DomainMethyl_CpG_DNA-bd

SETDB1 SETDB2

2.69e-03111342IPR001739
DomainMBD

SETDB1 SETDB2

2.69e-03111342PF01429
DomainDNA-bd_dom

SETDB1 SETDB2

2.69e-03111342IPR016177
DomainPeripla_BP_I

GRIN2A GRIN2B GRM5

2.73e-03391343IPR028082
DomainEGF-like_CS

RELN LAMA2 LRP1B TENM3 LRP2 LRP5 C8A

2.80e-032611347IPR013032
DomainEGF_2

RELN LAMA2 LRP1B TENM3 LRP2 LRP5 C8A

3.05e-032651347PS01186
DomainP_trefoil_dom

MGAM SI

3.22e-03121342IPR000519
DomainOLF

MYOC ADGRL1

3.78e-03131342PF02191
DomainOLF

MYOC ADGRL1

3.78e-03131342PS51132
Domain-

BSPH1 MMP2

3.78e-031313422.10.10.10
DomainNHL

NHLRC3 TENM3

3.78e-03131342PS51125
DomainOlfac-like_dom

MYOC ADGRL1

3.78e-03131342IPR003112
DomainOLF

MYOC ADGRL1

3.78e-03131342SM00284
DomainDynein_heavy_chain_D4_dom

DNAH2 DNAH8

4.39e-03141342IPR024317
DomainFN_type2_col-bd

BSPH1 MMP2

4.39e-03141342IPR000562
DomainFN2_2

BSPH1 MMP2

4.39e-03141342PS51092
DomainDynein_HC_stalk

DNAH2 DNAH8

4.39e-03141342IPR024743
DomainDynein_heavy_dom-2

DNAH2 DNAH8

4.39e-03141342IPR013602
DomainDHC_N2

DNAH2 DNAH8

4.39e-03141342PF08393
DomainATPase_dyneun-rel_AAA

DNAH2 DNAH8

4.39e-03141342IPR011704
DomainFN2_1

BSPH1 MMP2

4.39e-03141342PS00023
DomainTUDOR

TDRD1 AKAP1

4.39e-03141342PF00567
DomainMT

DNAH2 DNAH8

4.39e-03141342PF12777
DomainAAA_8

DNAH2 DNAH8

4.39e-03141342PF12780
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

FUT10 ERBB2 DMXL2 RPS6KA4 DNAH2 CPNE5 LRP1B DMXL1 NEDD4 ADAMTS12 ADAMTS6 DNAH17 LRP2 USP4 MMP2 SSH2

4.62e-087301401634857952
Pubmed

mGluR5 and NMDA receptors drive the experience- and activity-dependent NMDA receptor NR2B to NR2A subunit switch.

GRIN2A GRIN2B GRM5

6.38e-083140321521618
Pubmed

Making of a Synapse: Recurrent Roles of Drebrin A at Excitatory Synapses Throughout Life.

GRIN2A GRIN2B DBN1

6.38e-083140328865018
Pubmed

Impaired maturation of dendritic spines without disorganization of cortical cell layers in mice lacking NRG1/ErbB signaling in the central nervous system.

ERBB2 LAMA2 GRIN2A GRIN2B

2.44e-0714140419240213
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

DMXL2 PDE4A CAD SGIP1 GRIN2A GRIN2B DBN1 GRM5 NEDD4 CAMKV ANAPC1 DCHS1 ARC SMARCC1 SSH2 TNS1 CDH11

3.69e-079631401728671696
Pubmed

Modified N-methyl-D-aspartate receptor subunit expression emerges in reeler Purkinje cells after accomplishment of the adult wild-type expression.

RELN GRIN2A GRIN2B

6.35e-07514039004271
Pubmed

Reelin signaling facilitates maturation of CA1 glutamatergic synapses.

RELN GRIN2A GRIN2B

6.35e-075140317229826
Pubmed

Tank Binding Kinase 1 modulates spindle assembly checkpoint components to regulate mitosis in breast and lung cancer cells.

ANAPC1 BUB1B CDC20

1.27e-066140333310066
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

CAD BTAF1 DBN1 HNRNPA2B1 ANAPC1 PRPF19 DMBT1 PLEC KIAA2012

1.72e-06272140931010829
Pubmed

The Mitotic Checkpoint Complex Requires an Evolutionary Conserved Cassette to Bind and Inhibit Active APC/C.

ANAPC1 BUB1B CDC20

2.21e-067140327939943
Pubmed

The internal Cdc20 binding site in BubR1 facilitates both spindle assembly checkpoint signalling and silencing.

ANAPC1 BUB1B CDC20

2.21e-067140325482201
Pubmed

Reelin deficiency causes specific defects in the molecular composition of the synapses in the adult brain.

RELN GRIN2A GRIN2B

2.21e-067140321664258
Pubmed

NMDA-receptor proteins are upregulated in the hippocampus of postnatal heterozygous reeler mice.

RELN GRIN2A GRIN2B

2.21e-067140316438943
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH2 DNAH17 DNAH8

2.21e-067140331178125
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ERBB2 PDE4A ARSJ POLE POLG ADGRL1 BTAF1 NUP214 EML3 TRAK1 SLC12A4 PCNX4 SCN5A ARC LRP5 LRRC14 PLEC

2.41e-0611051401735748872
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

ANPEP DBN1 NEB HNRNPA2B1 EIF2S2 LRP5 MMP2 PLEC

2.68e-06214140822199357
Pubmed

Systematic analysis of glutamatergic neurotransmission genes in alcohol dependence and adolescent risky drinking behavior.

GRIN2A GRIN2B GRM5

3.52e-068140318606955
Pubmed

Interphase APC/C-Cdc20 inhibition by cyclin A2-Cdk2 ensures efficient mitotic entry.

ANAPC1 BUB1B CDC20

3.52e-068140326960431
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

DPP6 DMXL2 CAD SGIP1 PTDSS1 ADGRL1 GRIN2A GRIN2B DBN1 GRM5 HNRNPA2B1 MGAT3 CAMKV EIF2S2 PRPF19 USP4 SSH2 PLEC TNS1

5.03e-0614311401937142655
Pubmed

Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population.

GRIN2B CAMKV SMARCC1 USP4 PLXNB1

5.29e-0662140519367581
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

DMXL2 ZDHHC16 NEB SLC12A4 TENM3 PCNX4 DISP3 MMP2 CDH11

6.77e-06322140926514267
Pubmed

The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction.

ANAPC1 BUB1B CDC20

7.50e-0610140318997788
Pubmed

Stable MCC binding to the APC/C is required for a functional spindle assembly checkpoint.

ANAPC1 BUB1B CDC20

7.50e-0610140324464857
Pubmed

The PP2AB56 phosphatase promotes the association of Cdc20 with APC/C in mitosis.

ANAPC1 BUB1B CDC20

1.03e-0511140328404789
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

LRP1B LRP2 LRP5

1.03e-0511140324639464
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

CAD DNAH2 PIWIL4 NUP214 HNRNPA2B1 SETDB2 SLC12A4 PCNX4 DCHS1 SMARCC1 DMBT1 TRIM47 AKAP1

1.21e-057541401335906200
Pubmed

Conformation-specific anti-Mad2 monoclonal antibodies for the dissection of checkpoint signaling.

ANAPC1 BUB1B CDC20

1.37e-0512140326986935
Pubmed

Expression profiling during mammary epithelial cell three-dimensional morphogenesis identifies PTPRO as a novel regulator of morphogenesis and ErbB2-mediated transformation.

ERBB2 PTPRO

1.61e-052140222851698
Pubmed

The glutamate receptor GluN2 subunit regulates synaptic trafficking of AMPA receptors in the neonatal mouse brain.

GRIN2A GRIN2B

1.61e-052140225131300
Pubmed

Loss of Nav1.5 expression and function in murine atria containing the RyR2-P2328S gain-of-function mutation.

RYR2 SCN5A

1.61e-052140223723061
Pubmed

Emerging roles of H3K9me3, SETDB1 and SETDB2 in therapy-induced cellular reprogramming.

SETDB1 SETDB2

1.61e-052140230850015
Pubmed

Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms.

GRIN2A GRIN2B

1.61e-052140220921396
Pubmed

The GRIN2B and GRIN2A Gene Variants Are Associated With Continuous Performance Test Variables in ADHD.

GRIN2A GRIN2B

1.61e-052140227199241
Pubmed

The role of NMDAR subtypes and charge transfer during hippocampal LTP induction.

GRIN2A GRIN2B

1.61e-052140216901514
Pubmed

Prognostic value of matrix metalloproteinase-2 (MMP-2), matrix metalloproteinase-9 (MMP-9) and aminopeptidase N/CD13 in breast cancer patients.

ANPEP MMP2

1.61e-052140221611838
Pubmed

Specific involvement of postsynaptic GluN2B-containing NMDA receptors in the developmental elimination of corticospinal synapses.

GRIN2A GRIN2B

1.61e-052140220696923
Pubmed

NMDA receptor subunit composition determines beta-amyloid-induced neurodegeneration and synaptic loss.

GRIN2A GRIN2B

1.61e-052140223618906
Pubmed

Formation of molecular complexes by N-methyl-D-aspartate receptor subunit NR2B and ryanodine receptor 2 in neonatal rat myocard.

GRIN2B RYR2

1.61e-052140215010472
Pubmed

Both NR2A and NR2B subunits of the NMDA receptor are critical for long-term potentiation and long-term depression in the lateral amygdala of horizontal slices of adult mice.

GRIN2A GRIN2B

1.61e-052140219474217
Pubmed

Importance of the GluN2B carboxy-terminal domain for enhancement of social memories.

GRIN2A GRIN2B

1.61e-052140226179233
Pubmed

A role for dendritic mGluR5-mediated local translation of Arc/Arg3.1 in MEF2-dependent synapse elimination.

GRM5 ARC

1.61e-052140224857654
Pubmed

Lack of NMDA receptor subtype selectivity for hippocampal long-term potentiation.

GRIN2A GRIN2B

1.61e-052140216033900
Pubmed

Disease-associated nonsense and frame-shift variants resulting in the truncation of the GluN2A or GluN2B C-terminal domain decrease NMDAR surface expression and reduce potentiating effects of neurosteroids.

GRIN2A GRIN2B

1.61e-052140238214768
Pubmed

[Different distribution of NMDA receptor subunits in cortex contributes to selective vulnerability of motor neurons in amyotrophic lateral sclerosis].

GRIN2A GRIN2B

1.61e-052140221503117
Pubmed

Functional contributions of synaptically localized NR2B subunits of the NMDA receptor to synaptic transmission and long-term potentiation in the adult mouse CNS.

GRIN2A GRIN2B

1.61e-052140218372311
Pubmed

Effects of GluN2A and GluN2B gain-of-function epilepsy mutations on synaptic currents mediated by diheteromeric and triheteromeric NMDA receptors.

GRIN2A GRIN2B

1.61e-052140232247039
Pubmed

Separate functional properties of NMDARs regulate distinct aspects of spatial cognition.

GRIN2A GRIN2B

1.61e-052140229764972
Pubmed

Increasing the GluN2A/GluN2B Ratio in Neurons of the Mouse Basal and Lateral Amygdala Inhibits the Modification of an Existing Fear Memory Trace.

GRIN2A GRIN2B

1.61e-052140227605622
Pubmed

Disease-associated GRIN protein truncating variants trigger NMDA receptor loss-of-function.

GRIN2A GRIN2B

1.61e-052140233043365
Pubmed

The Developmental Shift of NMDA Receptor Composition Proceeds Independently of GluN2 Subunit-Specific GluN2 C-Terminal Sequences.

GRIN2A GRIN2B

1.61e-052140230355491
Pubmed

N-methyl-D-aspartate receptor subunit NR2A and NR2B messenger RNA levels are altered in the hippocampus and entorhinal cortex in Alzheimer's disease.

GRIN2A GRIN2B

1.61e-052140212127670
Pubmed

Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes.

GRIN2A GRIN2B

1.61e-052140220890276
Pubmed

Roles of NMDA receptor NR2A and NR2B subtypes for long-term depression in the anterior cingulate cortex.

GRIN2A GRIN2B

1.61e-052140216045501
Pubmed

NR2A- and NR2B-NMDA receptors and drebrin within postsynaptic spines of the hippocampus correlate with hunger-evoked exercise.

GRIN2A GRIN2B

1.61e-052140227915379
Pubmed

p55CDC/hCDC20 is associated with BUBR1 and may be a downstream target of the spindle checkpoint kinase.

BUB1B CDC20

1.61e-052140211030144
Pubmed

Lupus autoantibodies act as positive allosteric modulators at GluN2A-containing NMDA receptors and impair spatial memory.

GRIN2A GRIN2B

1.61e-052140232179753
Pubmed

Virally mediated knock-down of NR2 subunits ipsilateral to the deprived eye blocks ocular dominance plasticity.

GRIN2A GRIN2B

1.61e-052140216944113
Pubmed

Attenuation of focal ischemic brain injury in mice deficient in the epsilon1 (NR2A) subunit of NMDA receptor.

GRIN2A GRIN2B

1.61e-05214029822733
Pubmed

N-Glycoform-dependent interactions of megalin with its ligands.

LRP2 FUT8

1.61e-052140227773703
Pubmed

NR2A and NR2B receptor gene variations modify age at onset in Huntington disease.

GRIN2A GRIN2B

1.61e-052140215742215
Pubmed

Purkinje Cells as Sources of Arrhythmias in Long QT Syndrome Type 3.

RYR2 SCN5A

1.61e-052140226289036
Pubmed

Therapeutic significance of NR2B-containing NMDA receptors and mGluR5 metabotropic glutamate receptors in mediating the synaptotoxic effects of β-amyloid oligomers on long-term potentiation (LTP) in murine hippocampal slices.

GRIN2B GRM5

1.61e-052140221310164
Pubmed

PTPRO promoter methylation is predictive of poorer outcome for HER2-positive breast cancer: indication for personalized therapy.

ERBB2 PTPRO

1.61e-052140224090193
Pubmed

Brain-region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice.

GRIN2A GRIN2B

1.61e-052140237657442
Pubmed

Individual NMDA receptor GluN2 subunit signaling domains differentially regulate the postnatal maturation of hippocampal excitatory synaptic transmission and plasticity but not dendritic morphology.

GRIN2A GRIN2B

1.61e-052140238813758
Pubmed

Two different mitotic checkpoint inhibitors of the anaphase-promoting complex/cyclosome antagonize the action of the activator Cdc20.

BUB1B CDC20

1.61e-052140218591651
Pubmed

Activation of intracellular metabotropic glutamate receptor 5 in striatal neurons leads to up-regulation of genes associated with sustained synaptic transmission including Arc/Arg3.1 protein.

GRM5 ARC

1.61e-052140222179607
Pubmed

Interaction between the α-glucosidases, sucrase-isomaltase and maltase-glucoamylase, in human intestinal brush border membranes and its potential impact on disaccharide digestion.

MGAM SI

1.61e-052140236968271
Pubmed

Dual Role of NMDAR Containing NR2A and NR2B Subunits in Alzheimer's Disease.

GRIN2A GRIN2B

1.61e-052140238731978
Pubmed

Differential Nanoscale Topography and Functional Role of GluN2-NMDA Receptor Subtypes at Glutamatergic Synapses.

GRIN2A GRIN2B

1.61e-052140230269991
Pubmed

Downregulation of hippocampal NR2A/2B subunits related to cognitive impairment in a pristane-induced lupus BALB/c mice.

GRIN2A GRIN2B

1.61e-052140231498792
Pubmed

Age-Dependent Changes in Synaptic NMDA Receptor Composition in Adult Human Cortical Neurons.

GRIN2A GRIN2B

1.61e-052140232191258
Pubmed

Distinct roles of GRIN2A and GRIN2B variants in neurological conditions.

GRIN2A GRIN2B

1.61e-052140231807283
Pubmed

The role of GluN2A and GluN2B NMDA receptor subunits in AgRP and POMC neurons on body weight and glucose homeostasis.

GRIN2A GRIN2B

1.61e-052140226500840
Pubmed

Chronic early postnatal scream sound stress induces learning deficits and NMDA receptor changes in the hippocampus of adult mice.

GRIN2A GRIN2B

1.61e-052140227015584
Pubmed

Plexin-B1/RhoGEF-mediated RhoA activation involves the receptor tyrosine kinase ErbB-2.

ERBB2 PLXNB1

1.61e-052140215210733
Pubmed

Hippocampal NMDA receptor subunits differentially regulate fear memory formation and neuronal signal propagation.

GRIN2A GRIN2B

1.61e-052140219806658
Pubmed

Subtype selective NMDA receptor antagonists induce recovery of synapses lost following exposure to HIV-1 Tat.

GRIN2A GRIN2B

1.61e-052140222142193
Pubmed

Genetic analysis in post-mortem samples with micro-ischemic alterations.

RYR2 SCN5A

1.61e-052140228086167
Pubmed

Conformational rearrangement of the NMDA receptor amino-terminal domain during activation and allosteric modulation.

GRIN2A GRIN2B

1.61e-052140233976221
Pubmed

Postnatal lethality of P-cadherin/desmoglein 3 double knockout mice: demonstration of a cooperative effect of these cell adhesion molecules in tissue homeostasis of stratified squamous epithelia.

DSG3 CDH3

1.61e-052140210771476
Pubmed

Directional gating of synaptic plasticity by GPCRs and their distinct downstream signalling pathways.

GRIN2A GRIN2B

1.61e-052140222334046
Pubmed

MMP-2 downregulation mediates differential regulation of cell death via ErbB-2 in glioma xenografts.

ERBB2 MMP2

1.61e-052140219578738
Pubmed

Contribution of the Individual Small Intestinal α-Glucosidases to Digestion of Unusual α-Linked Glycemic Disaccharides.

MGAM SI

1.61e-052140227480812
Pubmed

Role of N-methyl-d-aspartate receptor subunits GluN2A and GluN2B in auditory thalamocortical long-term potentiation in adult mice.

GRIN2A GRIN2B

1.61e-052140234197904
Pubmed

Roles of NMDA NR2B subtype receptor in prefrontal long-term potentiation and contextual fear memory.

GRIN2A GRIN2B

1.61e-052140216157280
Pubmed

N-Methyl-d-aspartic Acid (NMDA) Receptor Is Involved in the Inhibitory Effect of Ketamine on Human Sperm Functions.

GRIN2A GRIN2B

1.61e-052140234830255
Pubmed

PTPRO represses ERBB2-driven breast oncogenesis by dephosphorylation and endosomal internalization of ERBB2.

ERBB2 PTPRO

1.61e-052140227345410
Pubmed

NMDA Receptor C-Terminal Domain Signalling in Development, Maturity, and Disease.

GRIN2A GRIN2B

1.61e-052140236232696
Pubmed

Structural basis for substrate selectivity in human maltase-glucoamylase and sucrase-isomaltase N-terminal domains.

MGAM SI

1.61e-052140220356844
Pubmed

Opposing action of conantokin-G on synaptically and extrasynaptically-activated NMDA receptors.

GRIN2A GRIN2B

1.61e-052140222306487
Pubmed

Differential roles of NMDAR subunits 2A and 2B in mediating peripheral and central sensitization contributing to orofacial neuropathic pain.

GRIN2A GRIN2B

1.61e-052140236038077
Pubmed

ErbB-2 signals through Plexin-B1 to promote breast cancer metastasis.

ERBB2 PLXNB1

1.61e-052140222378040
Pubmed

Evolution of GluN2A/B cytoplasmic domains diversified vertebrate synaptic plasticity and behavior.

GRIN2A GRIN2B

1.61e-052140223201971
Pubmed

Barrel cortex critical period plasticity is independent of changes in NMDA receptor subunit composition.

GRIN2A GRIN2B

1.61e-052140211719203
Pubmed

Analysis of correlation between serum D-serine levels and functional promoter polymorphisms of GRIN2A and GRIN2B genes.

GRIN2A GRIN2B

1.61e-052140216266783
Pubmed

Effect of androgen blockade on HER-2 and matrix metalloproteinase-2 expression on bone marrow micrometastasis and stromal cells in men with prostate cancer.

ERBB2 MMP2

1.61e-052140223766685
Pubmed

Mechanistic Insight into NMDA Receptor Dysregulation by Rare Variants in the GluN2A and GluN2B Agonist Binding Domains.

GRIN2A GRIN2B

1.61e-052140227839871
Pubmed

Metaplasticity gated through differential regulation of GluN2A versus GluN2B receptors by Src family kinases.

GRIN2A GRIN2B

1.61e-052140222187052
Pubmed

NR2A and NR2B receptor gene variations modify age at onset in Huntington disease in a sex-specific manner.

GRIN2A GRIN2B

1.61e-052140217569088
GeneFamilyWD repeat domain containing

DMXL2 IFT172 CDC20B EML3 DMXL1 CDC40 WDR97 PRPF19 CDC20

1.06e-05262969362
GeneFamilyLow density lipoprotein receptors

LRP1B LRP2 LRP5

3.99e-0513963634
GeneFamilyDyneins, axonemal

DNAH2 DNAH17 DNAH8

9.35e-0517963536
GeneFamilyGlutamate ionotropic receptor NMDA type subunits

GRIN2A GRIN2B

5.76e-0479621201
GeneFamilyTudor domain containing

TDRD1 SETDB1 AKAP1

9.89e-0437963780
GeneFamilyZinc fingers CXXC-type|Methyl-CpG binding domain containing

SETDB1 SETDB2

1.49e-03119621025
GeneFamilyFucosyltransferases|Blood group antigens

FUT10 FUT8

2.09e-0313962434
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS12 ADAMTS6

4.50e-031996250
CoexpressionGSE17721_LPS_VS_CPG_0.5H_BMDC_DN

MYOC PHF7 ECSIT SDHAF2 ASAH1 FAM20B AKAP1 CARD14

1.14e-052001388M3983
CoexpressionMULLIGHAN_MLL_SIGNATURE_2_DN

RALGDS POLE DNAH2 DBN1 DMXL1 NEDD4 SLC12A4 MMP2 NAA16

1.79e-052791389M16867
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

AKAP6 DPP6 RALGDS RELN ENC1 ADGRL1 NEB GRM5 CPNE5 LRP1B DSCAML1 RYR2 GRIP1 WDR97 PTPRO GLRA2 SSH2 CATSPERG

2.12e-05110613818M39071
CoexpressionDESCARTES_FETAL_HEART_SATB2_LRRC7_POSITIVE_CELLS

GRIN2B GRM5 LRP1B CAMKV GLRA2 DISP3

3.36e-051151386M40201
CoexpressionDELYS_THYROID_CANCER_DN

DPP6 RELN MYOC LAMA2 NEB LRP1B RYR2 LRP2

3.40e-052331388M13273
CoexpressionYAGUE_PRETUMOR_DRUG_RESISTANCE_DN

DCHS1 MMP2 TNS1

3.93e-05131383M2070
CoexpressionLIM_MAMMARY_STEM_CELL_UP

RELN SGIP1 ENC1 ADGRL1 SLC12A4 TENM3 DCHS1 ARC MMP2 CDH3 TNS1

4.85e-0547913811M2573
CoexpressionLIM_MAMMARY_STEM_CELL_UP

RELN SGIP1 ENC1 ADGRL1 SLC12A4 TENM3 DCHS1 ARC MMP2 CDH3 TNS1

5.23e-0548313811MM1082
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM RELN GRIN2B NEB LRP1B DSCAML1 RYR2 DISP3 LRP2

7.27e-0918414092cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM RELN GRIN2B NEB LRP1B DSCAML1 RYR2 DISP3 LRP2

7.27e-091841409ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM RELN GRIN2B NEB LRP1B DSCAML1 RYR2 DISP3 LRP2

7.27e-0918414092b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGIP1 ARSJ PIWIL4 GRIP1 CAMKV DISP3 CATSPERG KLB

1.28e-0813714084dcb15de821439011df1bb0bbd7682d674bd725d
ToppCellfacs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGIP1 ARSJ PIWIL4 GRIP1 CAMKV DISP3 CATSPERG KLB

1.28e-081371408c05ceeb7b483324604cb3f647d2da2b3786071b1
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARSJ ENC1 LAMA2 P3H4 ADAMTS6 SPON2 MMP2 CDH11

1.12e-071811408d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCellCOVID-19-kidney-Epithelial_Doublet|COVID-19 / Disease (COVID-19 only), tissue and cell type

CHRNA9 GRIN2A LRP1B DSCAML1 BSPH1 MMD2 DNAH8

1.86e-0713014071ff28e9d3dc9a791e07d815f8fbb48f75d3f275b
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

DPP6 SGIP1 LAMA2 RYR2 ADAMTS12 TENM3 MMP2 CDH11

1.98e-071951408603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ENC1 LAMA2 P3H4 RYR2 TENM3 SPON2 MMP2 CDH11

2.05e-071961408525d6c8a277364e624e7cc586275f8a891436b57
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 GRIN2B LRP1B DSCAML1 RYR2 GRIP1 LRP2

7.62e-071601407c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 GRIN2B LRP1B DSCAML1 RYR2 GRIP1 LRP2

7.62e-07160140725c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

DPP6 RELN GRM5 DSCAML1 GRIP1 TENM3 LRP2

1.55e-061781407544379f5a6145429762258d426b876bb36c112f5
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

DPP6 SGIP1 LAMA2 RYR2 ADAMTS12 TENM3 CDH11

2.16e-06187140792d468dde81125d51daf7abd4703741abe1ab91c
ToppCellfacs-Skin-Telogen-3m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSG3 MYOC ENC1 IGDCC4 NEDD4 DUOXA1 TNS1

2.95e-06196140790edf61116ffcb4f8b6be3d0a05732d59b0a87d5
ToppCellfacs-Skin-Telogen-3m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSG3 MYOC ENC1 IGDCC4 NEDD4 DUOXA1 TNS1

2.95e-061961407c936014125b2ed5f796221b74acb77b8f8359875
ToppCellIPF-Stromal-Myofibroblast|IPF / Disease state, Lineage and Cell class

SGIP1 LAMA2 RYR2 ADAMTS12 TENM3 MMP2 CDH11

2.95e-0619614072d0a48e49b3b37bb66e33e74c52915911e1f8a74
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

SGIP1 LAMA2 RYR2 ADAMTS12 TENM3 MMP2 CDH11

3.05e-061971407f1c8936986123a3151140c374fcd62d6705c530b
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

SGIP1 LAMA2 RYR2 ADAMTS12 TENM3 MMP2 CDH11

3.05e-061971407fb847f2277609c31fffcdf49517243ce0684facf
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

ENC1 LAMA2 RYR2 ADAMTS12 TENM3 MMP2 CDH11

3.05e-061971407f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

SGIP1 LAMA2 RYR2 ADAMTS12 TENM3 MMP2 CDH11

3.15e-0619814073ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

SGIP1 LAMA2 RYR2 ADAMTS12 TENM3 MMP2 CDH11

3.15e-061981407df3de77216f5c5d6141ec44d01c56b942f611838
ToppCellFetal_29-31_weeks-Mesenchymal|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SGIP1 LAMA2 RYR2 ADAMTS12 TENM3 MMP2 CDH11

3.15e-06198140721cf4d81386761d09d0f6829c01c198e5524176d
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

SGIP1 LAMA2 RYR2 ADAMTS12 TENM3 MMP2 CDH11

3.26e-0619914074bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell343B-Fibroblasts-Fibroblast-G|343B / Donor, Lineage, Cell class and subclass (all cells)

DPP6 SGIP1 LAMA2 RYR2 ADAMTS12 MMP2 CDH11

3.26e-061991407f4b6c095cbe7a38b310adc49be4069e4d56e6a66
ToppCell343B-Fibroblasts-Fibroblast-G-|343B / Donor, Lineage, Cell class and subclass (all cells)

DPP6 SGIP1 LAMA2 RYR2 ADAMTS12 MMP2 CDH11

3.26e-0619914079c6d1c328bfbb6547f4c7bb2a784576a56bd72af
ToppCellBronchial-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SGIP1 LAMA2 RYR2 ADAMTS12 TENM3 MMP2 CDH11

3.37e-062001407389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell367C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|367C / Donor, Lineage, Cell class and subclass (all cells)

ENC1 LAMA2 P3H4 ADAMTS12 SPON2 MMP2 CDH11

3.37e-062001407082e718c1da3f4fdd33a001d15ad3ddb2be985c7
ToppCell367C-Fibroblasts-Fibroblast-B_(Myofibroblast)|367C / Donor, Lineage, Cell class and subclass (all cells)

ENC1 LAMA2 P3H4 ADAMTS12 SPON2 MMP2 CDH11

3.37e-062001407731e55070a7ff315091855bd88cda30e5a7e1a98
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SGIP1 LAMA2 RYR2 ADAMTS12 TENM3 MMP2 CDH11

3.37e-062001407cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

RELN DNAH2 GRIN2A GRM5 RYR2 KIAA2012

6.91e-061461406c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

RELN GRIN2A GRIN2B GRM5 LRP1B DNAH8

7.47e-061481406d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPT SLC26A9 TDRD1 LRP1B ADAMTS12 ADAMTS6

8.07e-061501406afd651c654e715414eff64cf3a37378d057a56a2
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|COVID-19 / Disease (COVID-19 only), tissue and cell type

RELN CHRNA9 SI GRM5 LRP1B DNAH8

8.07e-0615014060205318a870e091add66ee4305747dda9f51510d
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

RELN GRIP1 PTPRO GLRA2 SCN5A DISP3

9.73e-061551406105d59d8a1bb8cb37eef2c1767d737b2108ac7c5
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-cortical_neurons_1|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

PDE4A SGIP1 GRIN2A GRIN2B CPNE5 WDR97

1.09e-0515814061f94622186d8329357fa06785e03eeacf29ab1ce
ToppCellAdult-Mesenchymal-chondrocyte|Adult / Lineage, Cell type, age group and donor

SGIP1 LAMA2 RYR2 ADAMTS12 TNS1 CDH11

1.13e-0515914063f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

DPP6 GRM5 DSCAML1 GRIP1 TENM3 LRP2

1.54e-051681406a086c306be430adf0632ba53e98cd8014d2de330
ToppCellfacs-Heart-LV-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFT172 LAMA2 SPON2 GLRA2 MMP2 KLB

1.59e-051691406849a8f8509c58d65462a09c84d58b6ecdc8934f5
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Penk_Fst|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ARSJ ENC1 ETV6 TENM3 DISP3 ARC

2.00e-051761406a1b9f8f199a028b3fa85de43fe96bc29f387bfd8
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFT172 LAMA2 SPON2 GLRA2 MMP2 KLB

2.00e-051761406fee4e0f32aaf77294040c7af6c1f503571750d43
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFT172 LAMA2 SPON2 GLRA2 MMP2 KLB

2.00e-051761406f25251abd4ef9fb077a978f9f9f658af58e4e0d2
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CDC20B HNRNPA2B1 BUB1B SMS CDC20 CDH3

2.07e-05177140675049e5372d14edeb5768339359396b73a85c2cc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 LAMA2 GRIN2A ADAMTS12 TENM3 CDH11

2.13e-05178140678a0c6340001a77f5b2d890b6263f574af2e72da
ToppCell-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

SGIP1 MYOC LAMA2 ADAMTS12 MMP2 CDH11

2.20e-05179140610fadbaa1b6d21cbf9f354d717cc4c225619f4fd
ToppCellRA-11._Adipocyte|RA / Chamber and Cluster_Paper

GPT ACSS2 LRP1B ADAMTS12 TENM3 KLB

2.27e-051801406d48a3d27357f7d184132a6805950f93080146b59
ToppCellMesenchymal_cells-Stromal_fibro.|Mesenchymal_cells / Lineage and Cell class

RELN MYOC LAMA2 GRIN2B ARC MMP2

2.34e-051811406f8d914fdc06aaa75a4dc9158daf574ca28fa5432
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

GPT GRIN2A DSCAML1 RYR2 PTPRO LRP2

2.34e-051811406c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANPEP GPT SPON2 MMD2 C8A KLB

2.42e-051821406770ce9f3f4538d0181a0181543841bc964c68274
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast|PND01-03-samps / Age Group, Lineage, Cell class and subclass

ENC1 LAMA2 MGAT3 TENM3 SPON2 MMP2

2.42e-051821406812dac35b9aa05be48258082e007f6c00e7b4dd8
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANPEP GPT SPON2 MMD2 C8A KLB

2.42e-05182140677ab860e2add49dad0c1ffbfc64278ad499dfbd5
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANPEP GPT SPON2 MMD2 C8A KLB

2.42e-0518214064921c7d5687cc79f896b39753bb621d7e3d2972f
ToppCellB_cells-ISG-high_B_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

CPNE5 DMXL1 SAMD9L MGAT3 PTPRO DNAH8

2.49e-051831406dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 GRIN2A ADAMTS12 TENM3 DNAH8 CDH11

2.57e-051841406c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCelldroplet-Kidney-nan-21m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOC LAMA2 DUOXA1 SPON2 MMP2 CDH11

2.57e-0518414063bffadb0cb2e0d825bdb6cfc5d23f5436cbc3efd
ToppCelldroplet-Kidney-nan-21m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOC LAMA2 DUOXA1 SPON2 MMP2 CDH11

2.65e-05185140633cc0e9d8b54cb7408b51235f2a70e044ebae04d
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

AKAP6 LAMA2 CPNE5 RYR2 SCN5A ALPK3

2.65e-051851406549eeb521c3985bff396ea0f202db21822efa51f
ToppCelldroplet-Fat-Scat-21m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANPEP LAMA2 DUOXA1 SPON2 MMP2 CDH11

2.65e-05185140601bbe1e09f9ccae837a03ea2cdd168fa10800942
ToppCelldroplet-Kidney-nan-21m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOC LAMA2 DUOXA1 SPON2 MMP2 CDH11

2.65e-0518514069954fc85b183c1cc45c3c24e3dadc7984ee6f649
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SGIP1 LAMA2 RYR2 ADAMTS12 MMP2 CDH11

2.73e-0518614065473283fb95cee556b1f6934cf72169b676b5bcc
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

GRIN2B LRP1B RYR2 PLEC DNAH8 CDH11

2.73e-05186140623b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellE16.5-samps-Mesenchymal-Myofibroblast|E16.5-samps / Age Group, Lineage, Cell class and subclass

ENC1 LAMA2 ADAMTS6 SPON2 SMS MMP2

2.73e-051861406e044b3428b7eacfdc72d0f57cdabaa1de04c74cd
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHRNA9 GRIN2B GRM5 CPNE5 RYR2 CAMKV

2.73e-0518614067278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPT ENC1 DDIT4L MMD2 DMBT1 TNS1

2.81e-0518714069aa411ae9b5a923378a5daebb8bb2fc2613f2510
ToppCellCOVID-19-kidney-Fibroblast-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

SGIP1 GRIN2A ADAMTS12 TENM3 TNS1 CDH11

2.81e-05187140676bfe8c42430a230a8bdf299575c444fb7780f24
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

AKAP6 NEB CPNE5 RYR2 GRIP1 SCN5A

2.90e-0518814066d249fe92d51a19da19ec14bb2262d394255d577
ToppCelldroplet-Fat-Scat-21m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANPEP LAMA2 DUOXA1 SPON2 MMP2 CDH11

2.90e-051881406e54e09d34e263d5709c337914809e61e74e20591
ToppCelldroplet-Fat-Scat-21m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANPEP LAMA2 DUOXA1 SPON2 MMP2 CDH11

2.90e-0518814067fc9810ab14354cb512e2b1285562009c10203f5
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GRIN2A GRIN2B TMEM235 GRIP1 LRP2 CDH3

2.90e-0518814069655a4c47b644a870017d349b99063e17dbae572
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Striatum / BrainAtlas - Mouse McCarroll V32

ENC1 GRIN2A GRIN2B GRM5 CPNE5 CAMKV

2.90e-051881406e34ea7014c5a059a7db38f78bd903cf02616ddd3
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

RELN SGIP1 GRIN2B CPNE5 DSCAML1 NEDD4

2.90e-051881406aeecbc057dc823f8fcea8a98f18d213bacc7f4db
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 GRIN2A ADAMTS12 TENM3 DNAH8 CDH11

2.99e-05189140671397e993a77d70b2eeede240bdfc7660b558987
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 GRIN2A ADAMTS12 TENM3 DNAH8 CDH11

2.99e-0518914064eea4759520c312bd17a681034d8074e47093d2b
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANPEP MYOC LAMA2 DBN1 DUOXA1 MMP2

2.99e-0518914060a8b827bba1efd885ad6c06929251c741dc3a541
ToppCell(2)_NK/T-(210)_NKT_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

ERBB2 PDE4A SAMD9L SPON2 TRIM56 SMARCC1

2.99e-051891406fa72e87e1e8cd7cbddae7b47e19cf90d181820a7
ToppCell(2)_NK/T-(21)_NKT_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

ERBB2 PDE4A SAMD9L SPON2 TRIM56 SMARCC1

2.99e-051891406b37ad24898a14a4a3b2d6cea2637de2471f76e20
ToppCellAdult|World / Lineage, Cell type, age group and donor

DMXL2 ANPEP ACSS2 DUOXA1 LRP2 DMBT1

2.99e-0518914065cd285bfad973125d46d704fec18b21266a63379
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE4A ENC1 DMXL1 TRAK1 PTPRO ASAH1

3.08e-051901406ed100e271aac82806f59e0c613ccda63f59100c1
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

DPP6 GRIN2B GRM5 CPNE5 RYR2 ASAH1

3.08e-0519014066e92c78799f34b31d098854503c796edb0dc7f80
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

SGIP1 LAMA2 RYR2 ADAMTS12 TENM3 CDH11

3.08e-0519014063a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RYR2 IGDCC4 ADAMTS12 TENM3 MMP2 CDH11

3.17e-051911406b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

GRIN2A GRIN2B TMEM235 GRIP1 LRP2 CDH3

3.17e-0519114064c4eb61e6179d2f8fc524d2f813db9cba84f67a2
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP6 MTFP1 CPNE5 RYR2 SCN5A ALPK3

3.17e-051911406c172c9e17b893b290e4aa8af5e5e4cd3e4818372
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

DPP6 RELN GRIN2B LRP1B RYR2 GRIP1

3.17e-051911406156b467187331ac6ca390d6ca861d9670bb7b956
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP6 MTFP1 CPNE5 RYR2 SCN5A ALPK3

3.17e-051911406715f5b449b8e075959c05a5b38389df319663164
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SGIP1 LAMA2 RYR2 ADAMTS12 TENM3 CDH11

3.17e-0519114066688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

DPP6 SLC26A9 ACSS2 DUOXA1 LRP2 DMBT1

3.26e-05192140658c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SGIP1 LAMA2 RYR2 ADAMTS12 TENM3 CDH11

3.26e-05192140699ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRL1 GRIN2B GRM5 CPNE5 RYR2 CAMKV

3.36e-051931406be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA2 IGDCC4 ADAMTS12 TENM3 MMP2 CDH11

3.36e-051931406b05361ffe111a38cfa26eb86e4ae62c15ac99b7b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 LAMA2 GRIN2A ADAMTS12 TENM3 CDH11

3.36e-051931406c8c21eee8c6c086dc2faf416669cd4a002870fbe
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA2 PIWIL4 NEB ADAMTS12 MMP2 CDH11

3.36e-0519314065bee7abc550ddaa28cbb3b9ecaf6b924ab175de0
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

SGIP1 LAMA2 RYR2 SPON2 MMP2 CDH11

3.36e-051931406e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

SGIP1 LAMA2 RYR2 ADAMTS12 TENM3 CDH11

3.36e-051931406ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRL1 GRIN2B GRM5 CPNE5 RYR2 CAMKV

3.36e-0519314060c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRL1 GRIN2B GRM5 CPNE5 RYR2 CAMKV

3.36e-0519314068689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 LAMA2 GRIN2A ADAMTS12 TENM3 CDH11

3.36e-0519314065b602b1702283184bd3943c2a6f2290b7c37e407
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SGIP1 LAMA2 RYR2 ADAMTS12 TNS1 CDH11

3.46e-051941406e93de9428c986b8943fc169258847c650cfab0e5
ToppCellControl-Fibroblasts-Intermediate_pathological_FB|Control / group, cell type (main and fine annotations)

SGIP1 LAMA2 RYR2 ADAMTS12 TENM3 CDH11

3.46e-05194140603a269f75a481ea54aea8e6444605db8d6df493d
ToppCell10x5'v1-week_17-19-Myeloid_neutrophil-granulo-neutrophil-neutrophil|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MGAM DMXL2 PDE4A ANPEP NUP214 ASAH1

3.46e-051941406e2d0dfb92356fa7ad7008aa8ac4198e2ac5d2495
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SGIP1 IGDCC4 ADAMTS12 TENM3 MMP2 CDH11

3.46e-05194140660622bd2f75bfe4c37f721cb12f03dab33f2f58d
Drugciguatoxin 3C

GRIN2A GRIN2B ARC

2.07e-0651363ctd:C466858
DrugBenzamil hydrochloride [2898-76-2]; Down 200; 11.2uM; PC3; HT_HG-U133A

ZNF573 ETV6 ADGRL1 RYR2 TENM3 FAM20B LRP2 DMBT1 TNS1

3.20e-0619913694294_DN
DrugBeta-Escin [11072-93-8]; Down 200; 3.2uM; MCF7; HT_HG-U133A

INPP5K POLG ETV6 ADGRL1 TRAK1 NEDD4 ARC LRRC14 CARD14

3.33e-0620013694364_DN
Drugkynurenic acid

MGAM CHRNA9 INPP5K GRIN2A GRIN2B GRM5 GLRA2

8.79e-061221367CID000003845
Drugavermectin

GRIN2A GRIN2B GRM5 GLRA2 C8A

9.84e-06481365CID006450460
DrugWT702

GRIN2A GRIN2B GLRA2

1.14e-0581363CID000089643
DrugRS)-2-chloro-5-hydroxyphenylglycine

RELN GRIN2A GRIN2B GRM5

1.18e-05241364CID003645780
Drugmemantine

CHRNA9 GRIN2A GRIN2B DBN1 GRM5 GLRA2

1.29e-05861366CID000004054
DrugNS3763

GRIN2A GRIN2B GRM5

1.71e-0591363CID004359312
DrugL-689,560

GRIN2A GRIN2B GRM5 GLRA2

1.92e-05271364CID000121918
DrugAC1L1ICP

GRIN2A GRIN2B SLC12A4

2.43e-05101363CID000004520
DrugAC1NUW3V

GRIN2A GRIN2B GRM5 GLRA2

2.58e-05291364CID005462126
DrugMelatonin [73-31-4]; Down 200; 17.2uM; MCF7; HT_HG-U133A

INPP5K ETV6 ADGRL1 NEB TRAK1 MGAT3 PLEC PLXNB1

2.58e-0519813685393_DN
Drugpilocarpine-

CHRNA9 DSG3 MYOC GRIN2A GRIN2B GRM5 HNRNPA2B1

2.95e-051471367CID000004819
Drugcis-2,3-piperidine dicarboxylic acid

MGAM GRIN2A GRIN2B GRM5

2.96e-05301364CID000001226
DrugNPC 12626

GRIN2A GRIN2B GRM5 GLRA2

3.38e-05311364CID000108099
DrugLY235959

GRIN2A GRIN2B GRM5 GLRA2

3.38e-05311364CID000131938
Drugeliprodil

GRIN2A GRIN2B GRM5 GLRA2

3.38e-05311364CID000060703
Drugcyclopentylcarbamoylphosphonic acid

MGAM MMP2

3.54e-0521362CID010198038
DrugYoYo-3

ERBB2 SCN5A

3.54e-0521362CID006444584
Drugalpha-methyl-4-carboxyphenylglycine

INPP5K GRIN2A GRIN2B GRM5

3.85e-05321364CID000001222
Drugoriens

RELN CHRNA9 NUP214 GRIN2A GRIN2B GRM5 ARC

3.98e-051541367CID000161645
Druggalloylglucose

MGAM SI MMP2

5.71e-05131363CID000124375
Drugmonomethyl phthalate

DPP6 MGAM ERBB2 CAD ANPEP MYOC SETDB2 SLC12A4 ASAH1 EIF2S2 ARC SMARCC1 USP4 CDC20 FUT8 DEDD CDH11

5.81e-0595713617ctd:C517284
DrugC6H12NO5P

GRIN2A GRIN2B GRM5 GLRA2

6.18e-05361364CID000104962
Druggabapentin

ANPEP GPT GRIN2A GRIN2B GRM5 RYR2 SCN5A

7.17e-051691367CID000003446
DrugAC1L9FMM

DSG3 GRIN2A GRIN2B GRM5 GLRA2

7.66e-05731365CID000444055
DrugGAMs

MGAM SI GRIN2A GRIN2B

7.68e-05381364CID000002935
Diseasecognitive disorder (biomarker_via_orthology)

GRIN2A GRIN2B DBN1

5.63e-0681393DOID:1561 (biomarker_via_orthology)
Disease1,5 anhydroglucitol measurement

MGAM PCDHA11 PCDHA10 SI

1.02e-05291394EFO_0008009
DiseaseVentricular Fibrillation, Paroxysmal Familial, 1

DPP6 SCN5A

2.20e-0521392C2751898
DiseaseVENTRICULAR FIBRILLATION DURING MYOCARDIAL INFARCTION, SUSCEPTIBILITY TO

DPP6 SCN5A

2.20e-0521392C4017668
DiseaseParoxysmal familial ventricular fibrillation

DPP6 SCN5A

2.20e-0521392cv:C0340493
DiseaseAlcoholic Intoxication, Chronic

SGIP1 GRIN2A GRIN2B DSCAML1 ANAPC1 ARC MMP2 CDH11

4.21e-052681398C0001973
DiseaseAutism Spectrum Disorders

DPP6 RELN GRIN2B RYR2 GLRA2

5.23e-05851395C1510586
Diseaseheart valve disease (is_marker_for)

LRP5 MMP2

6.59e-0531392DOID:4079 (is_marker_for)
DiseaseArrhythmogenic Right Ventricular Dysplasia

RYR2 SCN5A

6.59e-0531392C0349788
DiseaseSchizophrenia

RELN PDE4A LAMA2 GRIN2A GRIN2B DBN1 GRM5 TRAK1 ADAMTS12 SETDB1 ASAH1 LRP2 ARC FUT8

7.69e-0588313914C0036341
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

GRIN2A GRIN2B PLXNB1 NAA16

8.48e-05491394DOID:0060037 (implicated_via_orthology)
DiseaseBipolar Disorder

RELN PDE4A POLG GRIN2A GRIN2B DBN1 GRM5 NEDD4 SMS DNAH8

9.23e-0547713910C0005586
DiseaseParoxysmal familial ventricular fibrillation

DPP6 SCN5A

1.31e-0441392C0340493
Diseaseintraocular pressure measurement

RELN TTC41P ANPEP MYOC KBTBD7 NEDD4 ADAMTS6 ANAPC1 TNS1 CDH11

1.56e-0450913910EFO_0004695
Diseaseligament rupture

DPP6 FAM20B

2.18e-0451392EFO_1002012
Diseasealcohol consumption measurement

AKAP6 DPP6 MGAM RELN CAD SGIP1 IFT172 DNAH2 GRIN2B GRM5 CPNE5 GRIP1 SDHAF2 FUT8 CDH11 KLB

2.58e-04124213916EFO_0007878
DiseaseRS-warfarin measurement

LRP1B DSCAML1 SCN5A ALPK3 C8A

3.59e-041281395EFO_0803325
Diseaseresting heart rate, chronic obstructive pulmonary disease

FUT8 TNS1 CDH11

3.78e-04301393EFO_0000341, EFO_0004351
Diseasebitter alcoholic beverage consumption measurement

DPP6 MGAM RELN DNAH2 KLB

4.28e-041331395EFO_0010092
DiseaseColorectal Carcinoma

AKAP6 RALGDS CAD POLE GRIN2A DSCAML1 BUB1B DCHS1 LRP2 MMP2 DNAH8

5.10e-0470213911C0009402
Diseaseheart function measurement

SCN5A ALPK3 PLEC

5.50e-04341393EFO_0004311
Diseasepack-years measurement, systolic blood pressure

LRP1B DCHS1 LRP2

5.50e-04341393EFO_0006335, EFO_0006526
DiseaseMalignant neoplasm of breast

AKAP6 ERBB2 INPP5K LAMA2 DNAJC21 PHF7 NUP214 DBN1 NEDD4 EIF2S2 MMP2 RMND1 TNS1 PLXNB1

5.66e-04107413914C0006142
Diseaseplacental insufficiency (biomarker_via_orthology)

GRIN2A GRIN2B

6.06e-0481392DOID:3891 (biomarker_via_orthology)
Diseasehousehold income

SGIP1 LRP1B CAMKV SMARCC1 USP4 LRRC14 UMAD1

6.16e-043041397EFO_0009695
Diseaseattention deficit hyperactivity disorder, autism spectrum disorder, intelligence

AKAP6 DMXL2 GRIN2A DBN1 MGAT3 CAMKV PTPRO USP4

6.20e-043981398EFO_0003756, EFO_0003888, EFO_0004337
Diseaseasparaginase-induced acute pancreatitis

NEB CDC20

7.76e-0491392EFO_1001507
Diseaseepilepsy (implicated_via_orthology)

GRIN2A GRIN2B LRP1B SLC12A4 SCN5A

1.07e-031631395DOID:1826 (implicated_via_orthology)
DiseaseDNA methylation

DPP6 ETV6 GRIN2B LRP1B TENM3 ADAMTS6 DCHS1 MMD2 CDH11 MMD2

1.13e-0365613910GO_0006306
DiseaseTachycardia, Ventricular

RYR2 SCN5A

1.18e-03111392C0042514
Diseasehyperhomocysteinemia (implicated_via_orthology)

GRIN2A GRIN2B

1.18e-03111392DOID:9279 (implicated_via_orthology)
DiseaseCognitive impairment

RYR2 DMXL1

1.18e-03111392HP_0100543
Diseasevascular dementia (is_marker_for)

GRIN2A GRIN2B

1.18e-03111392DOID:8725 (is_marker_for)
Diseasequality of life during menstruation measurement, dysmenorrheic pain measurement

ETV6 GRIN2A

1.18e-03111392EFO_0007889, EFO_0009366
DiseaseLong QT Syndrome

RYR2 SCN5A

1.18e-03111392C0023976
Diseasefibrinogen measurement, plasminogen activator inhibitor 1 measurement

NLRP3 TRIM56 PLEC

1.26e-03451393EFO_0004623, EFO_0004792
DiseaseAbnormality of refraction

AKAP6 LAMA2 PCDHA11 PCDHA10 GRIN2A GRIN2B DSCAML1 NEDD4 FER1L4 MMP2

1.36e-0367313910HP_0000539
Diseasecorneal resistance factor

ANPEP KBTBD7 NEDD4 ADAMTS6 ANAPC1 DISP3 TNS1 NAA16

1.38e-034511398EFO_0010067
DiseaseAlzheimer's disease (is_marker_for)

RELN GRIN2A GRIN2B DBN1 HNRNPA2B1 MMP2

1.41e-032571396DOID:10652 (is_marker_for)
DiseaseMetabolic Bone Disorder

LRP2 MMP2

1.93e-03141392C0005944
DiseaseDiabetic Neuralgia

GRM5 MMP2

1.93e-03141392C0751074
DiseaseDiabetic Neuropathies

GRM5 MMP2

1.93e-03141392C0011882
DiseaseAsymmetric Diabetic Proximal Motor Neuropathy

GRM5 MMP2

1.93e-03141392C0271674
DiseaseSymmetric Diabetic Proximal Motor Neuropathy

GRM5 MMP2

1.93e-03141392C0271673
DiseaseDiabetic Mononeuropathy

GRM5 MMP2

1.93e-03141392C0271678
DiseaseDiabetic Autonomic Neuropathy

GRM5 MMP2

1.93e-03141392C0271686
DiseaseDiabetic Amyotrophy

GRM5 MMP2

1.93e-03141392C0271685
DiseaseDiabetic Polyneuropathies

GRM5 MMP2

1.93e-03141392C0271680
DiseaseDiabetic Asymmetric Polyneuropathy

GRM5 MMP2

1.93e-03141392C0393835
DiseaseDrug habituation

ETV6 GRM5 NME7 DNAH8

2.18e-031151394C0013170
DiseaseDrug abuse

ETV6 GRM5 NME7 DNAH8

2.18e-031151394C0013146
DiseasePrescription Drug Abuse

ETV6 GRM5 NME7 DNAH8

2.18e-031151394C4316881
DiseaseSubstance-Related Disorders

ETV6 GRM5 NME7 DNAH8

2.18e-031151394C0236969
DiseaseDrug Use Disorders

ETV6 GRM5 NME7 DNAH8

2.18e-031151394C0013222
DiseaseDrug Dependence

ETV6 GRM5 NME7 DNAH8

2.18e-031151394C1510472
DiseaseSubstance Dependence

ETV6 GRM5 NME7 DNAH8

2.18e-031151394C0038580
DiseaseSubstance Use Disorders

ETV6 GRM5 NME7 DNAH8

2.18e-031151394C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

ETV6 GRM5 NME7 DNAH8

2.18e-031151394C0029231
Diseasecognitive decline measurement

DPP6 RELN POLG DSCAML1 ANAPC1 ARC FUT8 TNS1

2.20e-034861398EFO_0007710
DiseaseOsteopenia

LRP2 MMP2

2.22e-03151392C0029453
Diseasemyelodysplastic syndrome (implicated_via_orthology)

POLG SAMD9L

2.22e-03151392DOID:0050908 (implicated_via_orthology)
DiseaseSubstance abuse problem

ETV6 GRM5 NME7 DNAH8

2.25e-031161394C0740858
Diseaserefractive error, age at onset, Myopia

AKAP6 DPP6 LAMA2 GRIN2B DSCAML1

2.25e-031931395EFO_0004847, HP_0000545, MONDO_0004892
DiseaseCocaine-Related Disorders

GRM5 TENM3 ARC DNAH8

2.32e-031171394C0236736
Diseasealcohol use disorder (implicated_via_orthology)

ERBB2 ACSS2 RYR2 SMARCC1 SSH2

2.36e-031951395DOID:1574 (implicated_via_orthology)
DiseaseMyopia

AKAP6 USP43 LAMA2 GRIN2B DSCAML1 RYR2 FER1L4

2.39e-033851397HP_0000545
Diseasemyopia (is_implicated_in)

LAMA2 MMP2

2.53e-03161392DOID:11830 (is_implicated_in)
Diseasecolorectal cancer (is_implicated_in)

POLE GRIN2A LRP1B BUB1B

2.62e-031211394DOID:9256 (is_implicated_in)
DiseaseBenign neoplasm of stomach

ERBB2 POLE

2.86e-03171392C0153943
Diseaseocular hypertension (biomarker_via_orthology)

MYOC MMP2

2.86e-03171392DOID:9282 (biomarker_via_orthology)
DiseaseNeoplasm of uncertain or unknown behavior of stomach

ERBB2 POLE

2.86e-03171392C0496905
DiseaseCarcinoma in situ of stomach

ERBB2 POLE

2.86e-03171392C0154060
DiseaseAcute myeloid leukemia

ETV6 NUP214

2.86e-03171392cv:C0023467
DiseaseLEUKEMIA, ACUTE MYELOID

ETV6 NUP214

2.86e-03171392601626
Diseaset-tau measurement

ETV6 NUDCD3 ADAMTS12 UMAD1

3.03e-031261394EFO_0004760
DiseaseCocaine Abuse

GRM5 TENM3 ARC DNAH8

3.12e-031271394C0009171
Diseaselaryngeal squamous cell carcinoma (is_marker_for)

ERBB2 MMP2

3.57e-03191392DOID:2876 (is_marker_for)
Diseaset-tau:beta-amyloid 1-42 ratio measurement

SGIP1 ETV6 PCNX4

3.77e-03661393EFO_0007708
Diseasetemporal lobe epilepsy (is_marker_for)

RELN GRIN2B

3.96e-03201392DOID:3328 (is_marker_for)
Diseasesusceptibility to mononucleosis measurement

DNAH2 RYR2 DNAH8

4.27e-03691393EFO_0008403
DiseaseCocaine Dependence

GRM5 TENM3 ARC DNAH8

4.30e-031391394C0600427
DiseaseStomach Carcinoma

ERBB2 POLE

4.36e-03211392C0699791
Diseaserefractive error

AKAP6 LAMA2 GRIN2A GRIN2B DSCAML1 FER1L4

4.57e-033261396MONDO_0004892
DiseaseC-reactive protein measurement

AKAP6 DMXL2 CAD ZNF573 SGIP1 IFT172 ETV6 GRM5 EML3 NLRP3 CAMKV DNAH17 KIAA2012

4.66e-03120613913EFO_0004458

Protein segments in the cluster

PeptideGeneStartEntry
LLSYDGSENLSRFWY

UMAD1

111

C9J7I0
DQWYRASVLAYASEE

TDRD1

556

Q9BXT4
LAQFYISWAEEYEAR

BUB1B

151

O60566
AVQVDYYLDEERAWA

GPT

201

P24298
YYLDEERAWALDVAE

GPT

206

P24298
VTETEEIWYLLEGSY

CATSPERG

531

Q6ZRH7
ETLEEITGYLYISAW

ERBB2

401

P04626
SLVERGLAQWVDSYY

AKAP1

886

Q92667
IRNDYYLNLVDWSSG

CDC20

181

Q12834
EFYWYVDEGLSADNL

DISP3

376

Q9P2K9
YNGEWRELRYDSTCE

C8A

181

P07357
TLTEYASWEDYVAAR

ADGRL1

186

O94910
EYLRQVGGSEEYWLS

ARC

226

Q7LC44
TWYKDDTELDRYCGL

ALPK3

311

Q96L96
ESLLSDFDYWDYVVP

DDIT4L

26

Q96D03
YLTWDRDQYDGLDSI

CHRNA9

91

Q9UGM1
DLWLNEGFASYVEYL

ANPEP

406

P15144
SLDVYELDAKQGRWY

ASAH1

301

Q13510
QSYIWIGEEYDRESK

DMXL2

2696

Q8TDJ6
SELTYLDAFWRDYIN

DEDD

251

O75618
RDQDGYYWITGRIDD

ACSS2

556

Q9NR19
AYWILEDYSGALETL

DMXL1

1776

Q9Y485
KRDLDGSEDWVYYRI

ADAMTS12

81

P58397
SEGDDYYINGAWTID

ADAMTS6

761

Q9UKP5
YKLYWREVGAEEEAN

IGDCC4

661

Q8TDY8
AGNEYWIYSASTLER

MMP2

536

P08253
TGSDDDWEYLLNSDY

ANAPC1

701

Q9H1A4
TDLDEEYTDNWLAVY

DSG3

291

P32926
LWDYVYQLLSDSRYE

ETV6

341

P41212
VDADSGYNAWLSYEL

PCDHA11

596

Q9Y5I1
VAGEEELRGSYNWDY

DCHS1

3151

Q96JQ0
LGSSNLYFLSDDDWE

MMD2

51

Q8IY49
GWADRYDVTDGYQRE

GRM5

306

P41594
WTDARSDAIYSALYD

LRP1B

1441

Q9NZR2
VDSEYYNSLRWILEN

NEDD4

1096

P46934
WIADDYLRTFLTQDG

MGAT3

286

Q09327
VRENYTWSQDYTDLE

NUDCD3

186

Q8IVD9
WYYGVNNDSLEERLF

DNAAF2

611

Q9NVR5
YGYLSWGQALEEEEE

ARSJ

41

Q5FYB0
SLDWDSQVELYRAYV

MGAM

1366

O43451
GSLDWDSQVELYRAY

MGAM

2261

O43451
LASQYEVDGYNAWRD

FER1L4

1351

A9Z1Z3
ANDLTIDYADQRLYW

LRP5

806

O75197
IDYADQRLYWTDLDT

LRP5

811

O75197
YLEEYERDWYIGLVS

PCNX4

1051

Q63HM2
LDYQYDTPGLWELEE

PLXNB1

891

O43157
QEILDTLEDNRDWYY

PDE4A

666

P27815
TLEDNRDWYYSAIRQ

PDE4A

671

P27815
IDRNAENWCYYEGLE

NAA16

251

Q6N069
SISGYYEILWGDVDI

DNAH8

1291

Q96JB1
WERYLAEAQGTYEEL

POLG

441

P54098
YSWGGYTDIDLAVDE

MYOC

371

Q99972
LEVYFEPEDYLNWRS

KIAA2012

21

Q0VF49
YLSYIEEWDLVLAAS

NUP214

306

P35658
DTWVRYLGYANEVGE

MTFP1

16

Q9UDX5
DLTIDDSYWYRIVAS

LAMA2

2221

P24043
YDESCDLWSLGVILY

RPS6KA4

586

O75676
RNLYWTDYALETIEV

LRP2

1521

P98164
VDRSDGYVYWVDDSL

LRP2

2241

P98164
GYVYWVDDSLDIIAR

LRP2

2246

P98164
LTLDYEEDLLYWVDA

LRP2

2556

P98164
IREESAADWALYTYE

DBN1

21

Q16643
DFDIRAILDWDYYIE

POLE

1121

Q07864
YEYDTREDQWINIGT

KBTBD7

586

Q8WVZ9
AAYDVLSDPQERAWY

DNAJC21

51

Q5F1R6
AWAGSERDYTYEELL

EIF2S2

166

P20042
YTAQDEWALDSIYIG

RELN

1016

P78509
WEQAGEYSRAVDCYL

IFT172

1286

Q9UG01
LLYISWTYGDDTTDL

PTPRO

646

Q16827
VDADSGYNAWLSYEL

PCDHA10

596

Q9Y5I2
ATGDYLLSSSDDQYW

PRPF19

316

Q9UMS4
YDAWFDYLRLVESDA

CRNKL1

491

Q9BZJ0
AEYLSQEEYEAWSQR

CARD14

856

Q9BXL6
EVFDWILDQGYYSER

CAMKV

106

Q8NCB2
YRRLIYWECTDDGEA

BSPH1

96

Q075Z2
LSDLWDQEQYDSEYS

BTAF1

1826

O14981
SFERYSYLWTDNLQE

DNAH17

986

Q9UFH2
ALRWYLATGDDIYDV

DSCAML1

56

Q8TD84
DSDDRLYEAYVEWKL

FUT10

341

Q6P4F1
RDVNDYVSYAWVGDS

INPP5K

371

Q9BT40
ATTDSDLDYDYLQNW

CDH11

761

P55287
QWNDSRLAYSEYPDD

GLRA2

101

P23416
WLGYENESALNLYET

RALGDS

96

Q12967
TGLRNDYYLNILDWS

CDC20B

226

Q86Y33
SLLDGFEWQDAYTIR

KLB

461

Q86Z14
WLYYDYTNDLSIELD

SLC44A3

261

Q8N4M1
DERLVYESAINWISY

ENC1

206

O14682
ETLSLDWVYGYRGRD

EML3

246

Q32P44
EGVIYNGLSDWLYEE

DPP6

281

P42658
TYPDVGLSYEDWDRS

GRIP1

856

Q9Y3R0
VLDDVRCSGYESYLW

DMBT1

426

Q9UGM3
LDDVRCSGYESYLWS

DMBT1

926

Q9UGM3
YGEYDLSTNEWTDGI

DNAH2

2131

Q9P225
LSLYLDEYEETPWDA

DNAH2

4021

Q9P225
DDWDRRLLTTYINDY

DNAH2

4051

Q9P225
YNEEFTWRLGENYAE

DUOXA1

126

Q1HG43
DYLLRVQESISDFYW

RYR2

3876

Q92736
DQDQDYDYLNEWGSR

CDH3

801

P22223
QLDLEYVRSGWDNYE

ECSIT

331

Q9BQ95
AEWYDPNASLLRRYE

NME7

11

Q9Y5B8
NGDYDRTIKVEVYDW

CPNE5

241

Q9HCH3
DRLINEPSNDWDIYY

SDHAF2

106

Q9NX18
DEDVYRLWLDGYSVT

FIBP

16

O43427
LDWASGTLYQDRFDY

NLRP3

241

Q96P20
DLYYLSQTDGAGDWR

FUT8

166

Q9BYC5
DRYWPTADGRLVEYD

SMS

121

P52788
ALDRGTYYWEVEIIE

TRIM47

476

Q96LD4
WREQAALDLYPYDAG

SPON2

176

Q9BUD6
LYDSEEDIRSYWDLE

SLC26A9

761

Q7LBE3
WELEPGAFSDLYQRY

PHF7

231

Q9BWX1
RDSLDNSYYDWYILV

SAMD9L

406

Q8IVG5
AYDRYLKLWDTETGQ

CDC40

351

O60508
YNNRTYSIDDIDWSV

PIWIL4

306

Q7Z3Z4
VDSEATRNEWYDFYL

PIWIL4

756

Q7Z3Z4
WESLDLYLSDPENYL

SCN5A

301

Q14524
YWDRENLEGLYDKTC

RMND1

376

Q9NWS8
WDDGESIDTYERDLY

SI

1726

P14410
IYPYSSSQDDEEWLR

SMARCC1

206

Q92922
DYDNLEGLSWVDYGE

SLC12A4

16

Q9UP95
RAGTELTWDYNYEVG

SETDB1

1256

Q15047
RNGEVVEAWYGSDEY

AKAP6

616

Q13023
LRADTIYGYDHDDWL

TRAK1

56

Q9UPV9
YDEYEDGDLSSWINR

TMX3

211

Q96JJ7
DELRGEAGYYLTTWF

RINL

486

Q6ZS11
IYWDPADDLAADIYS

URGCP

156

Q8TCY9
RTELTWDYGYEAGTV

SETDB2

686

Q96T68
SLDGQWYSYDDSTVE

USP43

676

Q70EL4
WYSYDDSTVEPLRED

USP43

681

Q70EL4
DWDSETRRLYYDEQE

USP4

741

Q13107
EWEYLDPNQRDLYRD

ZNF573

41

Q86YE8
VASDYWYILEVADAG

TMEM235

26

A6NFC5
TEDGYFLRAWNYTVD

NHLRC3

91

Q5JS37
ETTEESLRNYYEQWG

HNRNPA2B1

31

P22626
DEEATDLLAYWNDTY

SSH2

361

Q76I76
GFYAEIDWERYNSPE

SGIP1

66

Q9BQI5
WEAEGYNLVLDSDLY

WDR97

6

A6NE52
QYEGESWRESARYLE

P3H4

46

Q92791
TYREGKLARWEYDES

FAM20B

241

O75063
DYNTSDPLIRWDSYD

TNS1

326

Q9HBL0
GGEDTILYSWDLRSY

TLE7

306

A0A1W2PR48
WNVLLEAGYDVSEAY

TTC41P

766

Q6P2S7
VGYEYESCLDLTLWE

TENM3

1081

Q9P273
REALEAESAWCYLYG

PLEC

3811

Q15149
ALWAGYSVDRLYELT

CAD

816

P27708
YGSWDLFREAYAAIE

ZDHHC16

216

Q969W1
YWLDPNLRYATREAD

PTDSS1

131

P48651
VVDLVGYRAGWYDEE

TRIM56

146

Q9BRZ2
VLWTTDIYGRLAADY

LRRC14

476

Q15048
LISVSYDDWDYSLEA

GRIN2A

276

Q12879
YDDWDYSLEARVRDG

GRIN2A

281

Q12879
SYDEWDYGLPARVRD

GRIN2B

281

Q13224
YDLQSDNLYKSDLEW

NEB

3376

P20929
YDLQSDNVYRADLEW

NEB

4346

P20929