Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmicrotubule motor activity

KIF13A KIF17 DNAH9 KIF3A KIF7 DNAH11

6.89e-0770896GO:0003777
GeneOntologyMolecularFunctionbenzodiazepine receptor binding

RIMBP3 RIMBP3C RIMBP3B

8.50e-075893GO:0030156
GeneOntologyMolecularFunctioncytoskeletal protein binding

SPTBN4 DLG5 ABLIM1 NDE1 DISC1 SPTBN2 PAWR HOOK2 ITPRID2 VPS16 JAKMIP3 KIF13A KIF17 IQGAP3 KIF3A KIF7 FARP2

6.09e-0610998917GO:0008092
GeneOntologyMolecularFunctioncytoskeletal motor activity

KIF13A KIF17 DNAH9 KIF3A KIF7 DNAH11

1.46e-05118896GO:0003774
GeneOntologyMolecularFunctiondynein light intermediate chain binding

HOOK2 DNAH9 DNAH11

2.59e-0428893GO:0051959
GeneOntologyMolecularFunctionmicrotubule binding

NDE1 HOOK2 JAKMIP3 KIF13A KIF17 KIF3A KIF7

4.54e-04308897GO:0008017
GeneOntologyMolecularFunctionactin filament binding

SPTBN4 ABLIM1 SPTBN2 ITPRID2 VPS16 IQGAP3

5.35e-04227896GO:0051015
GeneOntologyMolecularFunctioncalmodulin binding

SLC24A4 UBR4 IQCB1 KCNQ1 IQGAP3 PCNT

5.73e-04230896GO:0005516
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCD4 MORC2 KIF13A KIF17 DNAH9 KIF3A KIF7 DNAH11

7.87e-04441898GO:0016887
GeneOntologyMolecularFunctionphosphatase binding

SPTBN4 MTMR4 KCNQ1 PAWR ANAPC5 KIF3A

1.17e-03264896GO:0019902
GeneOntologyMolecularFunctionprotein phosphatase binding

MTMR4 KCNQ1 PAWR ANAPC5 KIF3A

2.49e-03210895GO:0019903
GeneOntologyMolecularFunctionplus-end-directed microtubule motor activity

KIF17 KIF3A

2.56e-0317892GO:0008574
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH9 DNAH11

2.87e-0318892GO:0008569
GeneOntologyMolecularFunctiontubulin binding

NDE1 HOOK2 JAKMIP3 KIF13A KIF17 KIF3A KIF7

3.02e-03428897GO:0015631
GeneOntologyMolecularFunctionsmall GTPase binding

DOCK3 DOCK5 DENND5B RBSN IQGAP3 KIF3A

3.13e-03321896GO:0031267
GeneOntologyMolecularFunctionsolute:potassium antiporter activity

SLC9A4 SLC24A4

3.20e-0319892GO:0022821
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

DOCK3 DOCK5 DENND5B ARHGEF15 FARP2

3.75e-03231895GO:0005085
GeneOntologyBiologicalProcesscilium organization

ABLIM1 TCHP YAP1 ODAD1 DISC1 IQCB1 KCNQ1 PTPN23 CEP131 TEKT5 KIF17 KIF3A PCNT

1.11e-074768813GO:0044782
GeneOntologyBiologicalProcesscilium assembly

ABLIM1 TCHP YAP1 ODAD1 DISC1 IQCB1 KCNQ1 PTPN23 CEP131 TEKT5 KIF3A PCNT

4.00e-074448812GO:0060271
GeneOntologyBiologicalProcessmicrotubule-based process

PHLDB1 NDE1 ODAD1 DISC1 SUN1 PDE4DIP CEP131 HOOK2 KIF13A TEKT5 KIF17 DNAH9 KIAA1614 KIF3A KIF7 PCNT DNAH11

2.02e-0610588817GO:0007017
GeneOntologyBiologicalProcessmicrotubule-based movement

NDE1 ODAD1 SUN1 CEP131 KIF13A TEKT5 KIF17 DNAH9 KIF3A KIF7 DNAH11

7.93e-064938811GO:0007018
GeneOntologyBiologicalProcessmicrotubule-based transport

NDE1 SUN1 CEP131 KIF13A KIF17 DNAH9 KIF3A DNAH11

1.27e-05253888GO:0099111
GeneOntologyBiologicalProcesspeptidyl-methionine modification

PDF NAA15 NAA16

2.08e-0513883GO:0018206
GeneOntologyBiologicalProcessorganelle assembly

DOCK5 ABLIM1 CNOT6L TCHP YAP1 ODAD1 DISC1 SPTBN2 IQCB1 KCNQ1 PTPN23 CEP131 TEKT5 KIF3A PCNT FARP2

2.24e-0511388816GO:0070925
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

ABLIM1 TCHP YAP1 ODAD1 DISC1 IQCB1 KCNQ1 PTPN23 CEP131 TEKT5 KIF3A PCNT

2.69e-056708812GO:0120031
GeneOntologyBiologicalProcesscell projection assembly

ABLIM1 TCHP YAP1 ODAD1 DISC1 IQCB1 KCNQ1 PTPN23 CEP131 TEKT5 KIF3A PCNT

3.34e-056858812GO:0030031
GeneOntologyBiologicalProcesscytoskeleton-dependent intracellular transport

NDE1 SUN1 CEP131 HOOK2 KIF13A KIF17 KIF3A

5.02e-05225887GO:0030705
GeneOntologyBiologicalProcesscytoplasm protein quality control by the ubiquitin-proteasome system

UBR5 UBR4

5.38e-053882GO:0071629
GeneOntologyBiologicalProcesscytoplasm protein quality control

UBR5 UBR4

5.38e-053882GO:0140455
GeneOntologyBiologicalProcesspositive regulation of chondrocyte development

HOXA11 HOXD11

5.38e-053882GO:1902761
GeneOntologyBiologicalProcesstransport along microtubule

NDE1 SUN1 CEP131 KIF13A KIF17 KIF3A

1.99e-04197886GO:0010970
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

PHLDB1 NDE1 ODAD1 DISC1 SUN1 PDE4DIP CEP131 HOOK2 KIAA1614 KIF3A PCNT

2.41e-047208811GO:0000226
GeneOntologyBiologicalProcessN-terminal protein amino acid modification

PDF NAA15 NAA16

2.53e-0429883GO:0031365
GeneOntologyBiologicalProcessplus-end-directed vesicle transport along microtubule

KIF13A KIF3A

2.67e-046882GO:0072383
GeneOntologyBiologicalProcesspolarized epithelial cell differentiation

DLG5 YAP1 LAMA1

2.80e-0430883GO:0030859
GeneOntologyBiologicalProcessnon-motile cilium assembly

DISC1 KCNQ1 CEP131 KIF3A

3.47e-0478884GO:1905515
GeneOntologyBiologicalProcessanterograde dendritic transport of neurotransmitter receptor complex

KIF17 KIF3A

3.73e-047882GO:0098971
GeneOntologyBiologicalProcessplus-end-directed organelle transport along microtubule

KIF13A KIF3A

3.73e-047882GO:0072386
GeneOntologyBiologicalProcessN-terminal peptidyl-methionine acetylation

NAA15 NAA16

3.73e-047882GO:0017196
GeneOntologyBiologicalProcessneuromuscular synaptic transmission

RIMBP3 RIMBP3C RIMBP3B

4.84e-0436883GO:0007274
GeneOntologyBiologicalProcessregulation of chondrocyte development

HOXA11 HOXD11

4.96e-048882GO:0061181
GeneOntologyBiologicalProcessprotein K11-linked ubiquitination

UBR5 UBR4 ANAPC5

5.25e-0437883GO:0070979
GeneOntologyCellularComponentmicrotubule associated complex

NDE1 ODAD1 DISC1 KIF13A KIF17 DNAH9 KIF3A KIF7 DNAH11

3.16e-08161909GO:0005875
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

SPTBN4 KRT3 KRT4 NDE1 TCHP DISC1 PDE4DIP PAWR HOOK2 VPS16 KIF13A TEKT5 KIF17 DNAH9 KIF3A KIF7 PCNT DNAH11

4.36e-088999018GO:0099513
GeneOntologyCellularComponentmicrotubule organizing center

TCP10L DLG5 NDE1 TCHP DISC1 KIAA1217 UBR4 IQCB1 PDE4DIP PTPN23 CEP131 HOOK2 KIF13A KIF17 KIF3A KIF7 SPATC1L PCNT

6.08e-089199018GO:0005815
GeneOntologyCellularComponentkinesin complex

NDE1 DISC1 KIF13A KIF17 KIF3A KIF7

6.48e-0849906GO:0005871
GeneOntologyCellularComponentcilium

DLG5 SLC24A4 TCHP TCP11X2 ODAD1 DISC1 IQCB1 KCNQ1 PTPN23 CEP131 TEKT5 KIF17 DNAH9 KIF3A KIF7 PCNT DNAH11

2.43e-078989017GO:0005929
GeneOntologyCellularComponentsupramolecular fiber

SPTBN4 KRT3 KRT4 NDE1 TCHP DISC1 PDE4DIP PAWR HOOK2 VPS16 KIF13A TEKT5 KIF17 DNAH9 KIF3A KIF7 PCNT DNAH11

2.32e-0611799018GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

SPTBN4 KRT3 KRT4 NDE1 TCHP DISC1 PDE4DIP PAWR HOOK2 VPS16 KIF13A TEKT5 KIF17 DNAH9 KIF3A KIF7 PCNT DNAH11

2.55e-0611879018GO:0099081
GeneOntologyCellularComponentmicrotubule

NDE1 DISC1 PDE4DIP HOOK2 KIF13A TEKT5 KIF17 DNAH9 KIF3A KIF7 PCNT DNAH11

3.00e-065339012GO:0005874
GeneOntologyCellularComponentmanchette

RIMBP3 RIMBP3C CEP131 RIMBP3B

6.08e-0628904GO:0002177
GeneOntologyCellularComponentciliary basal body

DLG5 DISC1 PTPN23 CEP131 KIF17 KIF7 PCNT

2.14e-05195907GO:0036064
GeneOntologyCellularComponentcentrosome

NDE1 TCHP DISC1 KIAA1217 UBR4 IQCB1 PDE4DIP CEP131 HOOK2 KIF13A KIF3A SPATC1L PCNT

2.49e-057709013GO:0005813
GeneOntologyCellularComponentdynein complex

ODAD1 DISC1 DNAH9 DNAH11

8.62e-0554904GO:0030286
GeneOntologyCellularComponentcytoplasmic region

PHLDB1 TCHP ODAD1 TEKT5 KIF17 DNAH9 KIF3A DNAH11

1.62e-04360908GO:0099568
GeneOntologyCellularComponentNatA complex

NAA15 NAA16

1.82e-045902GO:0031415
GeneOntologyCellularComponentaxoneme

ODAD1 TEKT5 KIF17 DNAH9 KIF3A DNAH11

2.74e-04207906GO:0005930
GeneOntologyCellularComponentciliary plasm

ODAD1 TEKT5 KIF17 DNAH9 KIF3A DNAH11

2.81e-04208906GO:0097014
GeneOntologyCellularComponentciliary transition zone

IQCB1 CEP131 KIF17 KIF3A

4.15e-0481904GO:0035869
GeneOntologyCellularComponentspectrin

SPTBN4 SPTBN2

6.47e-049902GO:0008091
GeneOntologyCellularComponentN-terminal protein acetyltransferase complex

NAA15 NAA16

8.07e-0410902GO:0031414
GeneOntologyCellularComponentcentriole

TCP10L IQCB1 CEP131 KIF3A PCNT

8.90e-04172905GO:0005814
GeneOntologyCellularComponentcell cortex

SPTBN4 PHLDB1 TCHP SPTBN2 PDE4DIP KIAA1614 IQGAP3

1.11e-03371907GO:0005938
GeneOntologyCellularComponentphotoreceptor connecting cilium

IQCB1 KIF17 KIF3A

1.16e-0348903GO:0032391
GeneOntologyCellularComponentouter dynein arm

ODAD1 DNAH9

1.18e-0312902GO:0036157
GeneOntologyCellularComponentHOPS complex

HOOK2 VPS16

1.61e-0314902GO:0030897
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

ODAD1 TEKT5 KIF17 DNAH9 KIF3A DNAH11

2.49e-03317906GO:0032838
GeneOntologyCellularComponentsperm head-tail coupling apparatus

CEP131 SPATC1L

2.68e-0318902GO:0120212
GeneOntologyCellularComponentphotoreceptor cell cilium

SLC24A4 IQCB1 KIF17 KIF3A

3.07e-03139904GO:0097733
GeneOntologyCellularComponentzymogen granule membrane

SLC9A4 KCNQ1

3.31e-0320902GO:0042589
GeneOntologyCellularComponentcell-cell junction

SPTBN4 DLG5 TCHP YAP1 SPTBN2 LAMA1 CCDC85C IQGAP3

3.96e-03591908GO:0005911
GeneOntologyCellularComponentmotile cilium

TCP11X2 TEKT5 DNAH9 KIF3A PCNT DNAH11

4.33e-03355906GO:0031514
GeneOntologyCellularComponent9+0 non-motile cilium

SLC24A4 IQCB1 KIF17 KIF3A

4.33e-03153904GO:0097731
GeneOntologyCellularComponentaxonemal dynein complex

ODAD1 DNAH9

5.16e-0325902GO:0005858
MousePhenodetached sperm flagellum

RIMBP3 RIMBP3C RIMBP3B SPATC1L

3.83e-0621734MP:0008893
DomainNatA_aux_su

NAA15 NAA16

2.30e-052902IPR021183
DomainNARP1

NAA15 NAA16

2.30e-052902PF12569
DomainKinesin_motor_CS

KIF13A KIF17 KIF3A KIF7

4.45e-0541904IPR019821
DomainKinesin-like_fam

KIF13A KIF17 KIF3A KIF7

5.39e-0543904IPR027640
DomainKINESIN_MOTOR_1

KIF13A KIF17 KIF3A KIF7

5.91e-0544904PS00411
Domain-

KIF13A KIF17 KIF3A KIF7

5.91e-05449043.40.850.10
DomainKinesin_motor_dom

KIF13A KIF17 KIF3A KIF7

5.91e-0544904IPR001752
DomainKinesin

KIF13A KIF17 KIF3A KIF7

5.91e-0544904PF00225
DomainKINESIN_MOTOR_2

KIF13A KIF17 KIF3A KIF7

5.91e-0544904PS50067
DomainKISc

KIF13A KIF17 KIF3A KIF7

5.91e-0544904SM00129
DomainDUF3528

HOXA11 HOXD11

6.87e-053902PF12045
DomainDUF3528

HOXA11 HOXD11

6.87e-053902IPR021918
DomainSpectrin_bsu

SPTBN4 SPTBN2

1.37e-044902IPR016343
DomainDOCK_N

DOCK3 DOCK5

2.27e-045902PF16172
DomainDOCK_N

DOCK3 DOCK5

2.27e-045902IPR032376
DomainZF_UBR

UBR5 UBR4

4.75e-047902PS51157
Domainzf-UBR

UBR5 UBR4

4.75e-047902PF02207
DomainZnf_UBR

UBR5 UBR4

4.75e-047902IPR003126
DomainZnF_UBR1

UBR5 UBR4

4.75e-047902SM00396
DomainSH3

RIMBP3 DOCK3 DOCK5 DLG5 RIMBP3C RIMBP3B

6.20e-04216906SM00326
DomainSH3

RIMBP3 DOCK3 DOCK5 DLG5 RIMBP3C RIMBP3B

6.20e-04216906PS50002
DomainDHC_N1

DNAH9 DNAH11

6.31e-048902PF08385
DomainDynein_heavy_dom-1

DNAH9 DNAH11

6.31e-048902IPR013594
DomainSH3_domain

RIMBP3 DOCK3 DOCK5 DLG5 RIMBP3C RIMBP3B

6.82e-04220906IPR001452
DomainSH3_2

RIMBP3 DOCK3 RIMBP3C RIMBP3B

7.92e-0486904IPR011511
DomainSH3_2

RIMBP3 DOCK3 RIMBP3C RIMBP3B

7.92e-0486904PF07653
DomainTPR-contain_dom

NAA15 TTC7B PTPN23 ANAPC5 NAA16

7.94e-04150905IPR013026
DomainPH_dom-spectrin-type

SPTBN4 SPTBN2

8.09e-049902IPR001605
DomainTPR_REGION

NAA15 TTC7B PTPN23 ANAPC5 NAA16

1.22e-03165905PS50293
DomainTPR

NAA15 TTC7B PTPN23 ANAPC5 NAA16

1.22e-03165905PS50005
DomainDOCK_C

DOCK3 DOCK5

1.23e-0311902IPR010703
DomainDHR-1_domain

DOCK3 DOCK5

1.23e-0311902IPR027007
DomainDHR_2

DOCK3 DOCK5

1.23e-0311902PS51651
DomainDHR_1

DOCK3 DOCK5

1.23e-0311902PS51650
DomainDOCK-C2

DOCK3 DOCK5

1.23e-0311902PF14429
DomainDHR-2

DOCK3 DOCK5

1.23e-0311902IPR027357
DomainDHR-2

DOCK3 DOCK5

1.23e-0311902PF06920
DomainDOCK

DOCK3 DOCK5

1.23e-0311902IPR026791
DomainGrpE_coiled_coil

KRT3 KRT4

1.47e-0312902IPR013805
DomainTPR_2

NAA15 TTC7B NAA16

1.80e-0350903PF07719
DomainTPR_2

NAA15 TTC7B NAA16

1.80e-0350903IPR013105
DomainDynein_heavy_chain_D4_dom

DNAH9 DNAH11

2.01e-0314902IPR024317
DomainDynein_HC_stalk

DNAH9 DNAH11

2.01e-0314902IPR024743
DomainDynein_heavy_dom-2

DNAH9 DNAH11

2.01e-0314902IPR013602
DomainDHC_N2

DNAH9 DNAH11

2.01e-0314902PF08393
DomainMT

DNAH9 DNAH11

2.01e-0314902PF12777
DomainAAA_8

DNAH9 DNAH11

2.01e-0314902PF12780
DomainATPase_dyneun-rel_AAA

DNAH9 DNAH11

2.01e-0314902IPR011704
DomainAAA_5

DNAH9 DNAH11

2.01e-0314902PF07728
DomainDHC_fam

DNAH9 DNAH11

2.31e-0315902IPR026983
DomainDynein_heavy_dom

DNAH9 DNAH11

2.31e-0315902IPR004273
DomainDynein_heavy

DNAH9 DNAH11

2.31e-0315902PF03028
DomainTPR

NAA15 TTC7B ANAPC5 NAA16

3.51e-03129904SM00028
DomainCH

SPTBN4 SPTBN2 IQGAP3

3.81e-0365903SM00033
DomainTPR_repeat

NAA15 TTC7B ANAPC5 NAA16

3.91e-03133904IPR019734
DomainCH

SPTBN4 SPTBN2 IQGAP3

4.69e-0370903PF00307
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

RIMBP3 DLG5 NDE1 TCHP UBR5 YAP1 KIAA1217 IQCB1 ZMYM2 CEP131 ITPRID2 ALDH3A2 PCNT

4.65e-09588911338580884
Pubmed

RIM-BP3 is a manchette-associated protein essential for spermiogenesis.

RIMBP3 RIMBP3C RIMBP3B

6.92e-08491319091768
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

UBR4 IQCB1 CCDC85C VPS16 URGCP RBCK1 KIF7 PCNT

9.20e-0821291833853758
Pubmed

Structure and evolution of RIM-BP genes: identification of a novel family member.

RIMBP3 RIMBP3C RIMBP3B

1.73e-07591317855024
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SPTBN4 ABLIM1 UBR5 KIAA1217 SPTBN2 UBR4 PDE4DIP ZMYM2 CEP131 JAKMIP3 LMTK3 KIF3A KIF7 PCNT

2.09e-07963911428671696
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

ABLIM1 TCHP UBR5 YAP1 CCDC85C CEP131 RASSF4 ALDH3A2 ANAPC5 KIF7

2.77e-07446911024255178
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

ABLIM1 RBSN TCHP CEP131 HOOK2 VPS16 KIF3A KIF7

3.34e-0725191829778605
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

DLG5 ABLIM1 RBSN PHLDB1 MTMR4 NAA15 YAP1 KIAA1217 IQCB1 CCDC85C CEP131 ITPRID2 KIF13A

3.88e-07861911336931259
Pubmed

Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome.

KIF13A KIF17 KIF3A KIF7

5.32e-07259149275178
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

RIMBP3 DLG5 RBSN NDE1 UBR5 KIAA1217 SPTBN2 CCDC85C PTPN23 PAWR KIF7 PCNT

2.35e-06853911228718761
Pubmed

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.

NDE1 TCHP IQCB1 PDE4DIP CEP131 PCNT

2.45e-0614691621399614
Pubmed

All kinesin superfamily protein, KIF, genes in mouse and human.

KIF13A KIF17 KIF3A KIF7

2.71e-063791411416179
Pubmed

Endogenous Cell Type-Specific Disrupted in Schizophrenia 1 Interactomes Reveal Protein Networks Associated With Neurodevelopmental Disorders.

NDE1 UBR5 DISC1 PDE4DIP VPS16 SF1

3.60e-0615691629961565
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

DOCK3 SPTBN4 ABLIM1 TTC7B SPTBN2 UBR4 PDE4DIP ZMYM2 JAKMIP3 SF1 KIF3A RBCK1 SPATC1L PCNT

6.18e-061285911435914814
Pubmed

Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.

RIMBP3 RIMBP3C RIMBP3B

6.18e-061491317662146
Pubmed

Coordination of two kinesin superfamily motor proteins, KIF3A and KIF13A, is essential for pericellular matrix degradation by membrane-type 1 matrix metalloproteinase (MT1-MMP) in cancer cells.

KIF13A KIF3A

6.77e-06291235122963
Pubmed

Absence of mutations in the HOXA11 and HOXD11 genes in children with congenital renal malformations.

HOXA11 HOXD11

6.77e-06291219255789
Pubmed

DISC1-kendrin interaction is involved in centrosomal microtubule network formation.

DISC1 PCNT

6.77e-06291218955030
Pubmed

RBCK1 is an endogenous inhibitor for triple negative breast cancer via hippo/YAP axis.

YAP1 RBCK1

6.77e-06291236280829
Pubmed

Comprehensive microarray analysis of Hoxa11/Hoxd11 mutant kidney development.

HOXA11 HOXD11

6.77e-06291216581055
Pubmed

Functional equivalence and rescue among group 11 Hox gene products in vertebral patterning.

HOXA11 HOXD11

6.77e-0629128660870
Pubmed

DISC1 localizes to the centrosome by binding to kendrin.

DISC1 PCNT

6.77e-06291215094396
Pubmed

Recessive DNAH9 Loss-of-Function Mutations Cause Laterality Defects and Subtle Respiratory Ciliary-Beating Defects.

ODAD1 DNAH9

6.77e-06291230471718
Pubmed

IQGAP3, a YAP Target, Is Required for Proper Cell-Cycle Progression and Genome Stability.

YAP1 IQGAP3

6.77e-06291234183451
Pubmed

Absence of radius and ulna in mice lacking hoxa-11 and hoxd-11.

HOXA11 HOXD11

6.77e-0629127596412
Pubmed

Families with the risk allele of DISC1 reveal a link between schizophrenia and another component of the same molecular pathway, NDE1.

NDE1 DISC1

6.77e-06291217185386
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

DOCK5 ABLIM1 PDF CNOT6L NDE1 TCHP YAP1 IQCB1 CCDC85C CEP131 IQGAP3 URGCP KIF3A KIF7

8.45e-061321911427173435
Pubmed

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.

RIMBP3 NDE1 CBY2 DISC1 PDE4DIP HOOK2 DMPK RBCK1

1.09e-0540291824722188
Pubmed

Assembly and Function of Heterotypic Ubiquitin Chains in Cell-Cycle and Protein Quality Control.

UBR5 UBR4 ANAPC5

1.15e-051791329033132
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ABLIM1 PHLDB1 UBR5 BAZ2A PDE4DIP KIF17 SNX19 PCNT

1.20e-0540791812693553
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

DENND5B PODNL1 ABLIM1 TCHP UBR4 PDE4DIP RIMBP3C CEP131 URGCP DNAH11

1.33e-05689911036543142
Pubmed

A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.

DLG5 KIAA1217 CEP131 PAWR PCNT

1.52e-0511891530979931
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

DOCK3 DOCK5 YAP1 DISC1 UBR4 ITPRID2 LMTK3 PCNT

1.78e-0543091835044719
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

MTMR4 TTC7B SPTBN2 SUN1 CCDC85C PTPN23 CEP131 ITPRID2 ALDH3A2 SNX19 KIF7 PCNT

1.88e-051049911227880917
Pubmed

Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1.

YAP1 KIF3A DNAH11

1.91e-052091317251353
Pubmed

UBR E3 ligases and the PDIA3 protease control degradation of unfolded antibody heavy chain by ERAD.

UBR5 UBR4

2.03e-05391232558906
Pubmed

Functional specificity of the Hoxa13 homeobox.

HOXA11 HOXD11

2.03e-05391211688568
Pubmed

PI3Kγ (Phosphoinositide 3-Kinase γ) Regulates Vascular Smooth Muscle Cell Phenotypic Modulation and Neointimal Formation Through CREB (Cyclic AMP-Response Element Binding Protein)/YAP (Yes-Associated Protein) Signaling.

YAP1 PIK3CG

2.03e-05391230651001
Pubmed

Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: evidence of epistasis and competitive binding.

NDE1 DISC1

2.03e-05391218469341
Pubmed

Intraflagellar transport velocity is governed by the number of active KIF17 and KIF3AB motors and their motility properties under load.

KIF17 KIF3A

2.03e-05391228761002
Pubmed

Association studies and gene expression analyses of the DISC1-interacting molecules, pericentrin 2 (PCNT2) and DISC1-binding zinc finger protein (DBZ), with schizophrenia and with bipolar disorder.

DISC1 PCNT

2.03e-05391219191256
Pubmed

Subcellular targeting of DISC1 is dependent on a domain independent from the Nudel binding site.

NDE1 DISC1

2.03e-05391215797709
Pubmed

Deletion of a HoxD enhancer induces transcriptional heterochrony leading to transposition of the sacrum.

HOXA11 HOXD11

2.03e-0539129250683
Pubmed

MTMR4 SNVs modulate ion channel degradation and clinical severity in congenital long QT syndrome: insights in the mechanism of action of protective modifier genes.

MTMR4 KCNQ1

2.03e-05391232173736
Pubmed

UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer.

NAA15 UBR5 UBR4

2.23e-052191337422473
Pubmed

DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation.

SPTBN4 DISC1 PCNT

2.57e-052291312812986
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

ABLIM1 PHLDB1 UBR5 PTPN23 ARHGEF15 PCNT

2.89e-0522591612168954
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

DLG5 NAA15 TCHP UBR5 BAZ2A SPTBN2 UBR4 SUN1 CEP131 ITPRID2 ALDH3A2 SNX19 KIF7 PCNT

3.14e-051487911433957083
Pubmed

OTUB1 modulates c-IAP1 stability to regulate signalling pathways.

UBR5 UBR4 RBCK1

3.37e-052491323524849
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

DLG5 ABLIM1 CNOT6L NDE1 BAZ2A ZMYM2 CEP131 ITPRID2 MORC2 ALDH3A2 TEKT5 ANAPC5 IQGAP3 FARP2

3.38e-051497911431527615
Pubmed

Hoxa 11 is upstream of Integrin alpha8 expression in the developing kidney.

HOXA11 HOXD11

4.05e-05491212060755
Pubmed

Clustering of Genetic Anomalies of Cilia Outer Dynein Arm and Central Apparatus in Patients with Transposition of the Great Arteries.

DNAH9 DNAH11

4.05e-05491236140829
Pubmed

Molecular motors: the driving force behind mammalian left-right development.

KIF3A DNAH11

4.05e-05491210652513
Pubmed

Nudel contributes to microtubule anchoring at the mother centriole and is involved in both dynein-dependent and -independent centrosomal protein assembly.

NDE1 PCNT

4.05e-05491216291865
Pubmed

A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons.

UBR5 UBR4

4.05e-05491216055722
Pubmed

FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left-right determination.

KIF3A DNAH11

4.05e-05491215889083
Pubmed

Left-right development: the roles of nodal cilia.

KIF3A DNAH11

4.05e-05491210704402
Pubmed

The substrate recognition domains of the N-end rule pathway.

UBR5 UBR4

4.05e-05491219008229
Pubmed

Three types of cilia including a novel 9+4 axoneme on the notochordal plate of the rabbit embryo.

KIF3A DNAH11

4.05e-05491217061268
Pubmed

Role of Ca2+ transients at the node of the mouse embryo in breaking of left-right symmetry.

KIF3A DNAH11

4.05e-05491232743070
Pubmed

Ciliary targeting of olfactory CNG channels requires the CNGB1b subunit and the kinesin-2 motor protein, KIF17.

KIF17 KIF3A

4.05e-05491216782012
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

NAA15 CNOT6L NDE1 UBR5 CCDC85C ZMYM2 CEP131 PAWR ALDH3A2 ANAPC5 IQGAP3 NAA16

4.79e-051155911220360068
Pubmed

An evolutionarily conserved N-terminal acetyltransferase complex associated with neuronal development.

NAA15 NAA16

6.74e-05591212888564
Pubmed

Genetic analysis of a Hoxd-12 regulatory element reveals global versus local modes of controls in the HoxD complex.

HOXA11 HOXD11

6.74e-0559129521905
Pubmed

DNAH11 Localization in the Proximal Region of Respiratory Cilia Defines Distinct Outer Dynein Arm Complexes.

DNAH9 DNAH11

6.74e-05591226909801
Pubmed

Hox11 expression characterizes developing zeugopod synovial joints and is coupled to postnatal articular cartilage morphogenesis into functional zones in mice.

HOXA11 HOXD11

6.74e-05591234010606
Pubmed

The centriolar satellite protein Cep131 is important for genome stability.

CEP131 PCNT

6.74e-05591222797915
Pubmed

Regulation of number and size of digits by posterior Hox genes: a dose-dependent mechanism with potential evolutionary implications.

HOXA11 HOXD11

6.74e-0559129391088
Pubmed

Duplication of the Hoxd11 gene causes alterations in the axial and appendicular skeleton of the mouse.

HOXA11 HOXD11

6.74e-05591212217321
Pubmed

Monocilia in the embryonic mouse heart suggest a direct role for cilia in cardiac morphogenesis.

KIF3A DNAH11

6.74e-05591218729223
Pubmed

A novel human NatA Nalpha-terminal acetyltransferase complex: hNaa16p-hNaa10p (hNat2-hArd1).

NAA15 NAA16

6.74e-05591219480662
Pubmed

Altered Hox expression and increased cell death distinguish Hypodactyly from Hoxa13 null mice.

HOXA11 HOXD11

6.74e-05591210470645
Pubmed

Characterization of hARD2, a processed hARD1 gene duplicate, encoding a human protein N-alpha-acetyltransferase.

NAA15 NAA16

6.74e-05591216638120
Pubmed

A Hox-Eya-Pax complex regulates early kidney developmental gene expression.

HOXA11 HOXD11

6.74e-05591217785448
Pubmed

Generation and expression of a Hoxa11eGFP targeted allele in mice.

HOXA11 HOXD11

6.74e-05591218942146
Pubmed

Different roles for KIF17 and kinesin II in photoreceptor development and maintenance.

KIF17 KIF3A

6.74e-05591219384852
Pubmed

Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes.

KRT3 KRT4 UBR5 UBR4

7.21e-058491429563501
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

ABLIM1 PHLDB1 UBR5 SPTBN2 SUN1 CEP131 PAWR ITPRID2 SF1 KIF7 PCNT

7.54e-051024911124711643
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

ABLIM1 PHLDB1 NDE1 UBR5 YAP1 KIAA1217 IQCB1 CCDC85C HOOK2 ANAPC5 FARP2

8.51e-051038911126673895
Pubmed

Ccdc13 is a novel human centriolar satellite protein required for ciliogenesis and genome stability.

CEP131 PCNT

1.01e-04691224816561
Pubmed

CFAP53 regulates mammalian cilia-type motility patterns through differential localization and recruitment of axonemal dynein components.

DNAH9 DNAH11

1.01e-04691233347437
Pubmed

Genetic analysis of a conserved sequence in the HoxD complex: regulatory redundancy or limitations of the transgenic approach?

HOXA11 HOXD11

1.01e-0469129733096
Pubmed

In vivo assembly of the axon initial segment in motor neurons.

SPTBN4 SPTBN2

1.01e-04691223728480
Pubmed

Evidence of statistical epistasis between DISC1, CIT and NDEL1 impacting risk for schizophrenia: biological validation with functional neuroimaging.

NDE1 DISC1

1.01e-04691220084519
Pubmed

Spectrins and ankyrinB constitute a specialized paranodal cytoskeleton.

SPTBN4 SPTBN2

1.01e-04691216687515
Pubmed

Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage.

DNAH9 KIF3A PCNT

1.07e-043591337890489
Pubmed

Proximity Mapping of CCP6 Reveals Its Association with Centrosome Organization and Cilium Assembly.

CEP131 KIF7 FARP2

1.37e-043891336674791
Pubmed

Bifurcating action of Smoothened in Hedgehog signaling is mediated by Dlg5.

DLG5 KIF7

1.41e-04791225644602
Pubmed

DISC1, PDE4B, and NDE1 at the centrosome and synapse.

NDE1 DISC1

1.41e-04791218983980
Pubmed

Non-homeodomain regions of Hox proteins mediate activation versus repression of Six2 via a single enhancer site in vivo.

HOXA11 HOXD11

1.41e-04791219716816
Pubmed

Genetic interaction of Gli3 and Alx4 during limb development.

HOXA11 HOXD11

1.41e-04791215968591
Pubmed

Choline kinase beta is required for normal endochondral bone formation.

HOXA11 HOXD11

1.41e-04791224637075
Pubmed

Mesomelic dysplasias associated with the HOXD locus are caused by regulatory reallocations.

HOXA11 HOXD11

1.41e-04791234408147
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH9 DNAH11

1.41e-04791231178125
Pubmed

In-frame deletion in a novel centrosomal/ciliary protein CEP290/NPHP6 perturbs its interaction with RPGR and results in early-onset retinal degeneration in the rd16 mouse.

KIF3A PCNT

1.41e-04791216632484
Pubmed

Proximity interactions among centrosome components identify regulators of centriole duplication.

ABLIM1 CEP131 KIF7 PCNT

1.47e-0410191424613305
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

DOCK3 BAZ2A SPTBN2 DNAH9

1.65e-041049149205841
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

ABLIM1 NAA15 BAZ2A KIAA1217 CCDC85C ZMYM2 PTPN23 ALDH3A2 SF1 PCNT

1.68e-04934911033916271
Pubmed

Spatacsin regulates directionality of lysosome trafficking by promoting the degradation of its partner AP5Z1.

UBR4 KIF13A

1.88e-04891237871017
Pubmed

Hox10 and Hox11 genes are required to globally pattern the mammalian skeleton.

HOXA11 HOXD11

1.88e-04891212869760
InteractionSTIL interactions

DOCK5 DLG5 ABLIM1 NAA15 TCHP DISC1 KIAA1217 CEP131 KIF7 PCNT

1.30e-081909010int:STIL
InteractionNINL interactions

DLG5 ABLIM1 RBSN NDE1 TCHP UBR5 CBY2 KIAA1217 CCDC85C CEP131 ALDH3A2 IQGAP3 KIF7 PCNT

1.50e-084589014int:NINL
InteractionWHAMMP3 interactions

NDE1 YAP1 DISC1 CEP131 HOOK2 VPS16 KIF3A PCNT

6.03e-08119908int:WHAMMP3
InteractionPRPH interactions

TCP10L KRT3 ABLIM1 TCHP YAP1 KIAA1217 FAM167A CCDC85C KIF7

3.25e-07204909int:PRPH
InteractionDISC1 interactions

SPTBN4 RBSN NDE1 UBR5 DISC1 PDE4DIP VPS16 SF1 KIF3A KIF7 SPATC1L PCNT

4.54e-074299012int:DISC1
InteractionSYNE3 interactions

DLG5 ABLIM1 TCHP KIAA1217 SUN1 CCDC85C CEP131 ITPRID2 ALDH3A2 SNX19 KIF7 PCNT

6.53e-074449012int:SYNE3
InteractionKRT15 interactions

KRT3 KRT4 ABLIM1 CCDC185 TCHP YAP1 KIAA1217 IQCB1

1.32e-06178908int:KRT15
InteractionHOOK2 interactions

ABLIM1 TCHP IQCB1 FAM167A HOOK2 VPS16 ALDH3A2 SPATC1L

1.44e-06180908int:HOOK2
InteractionCEP55 interactions

MTMR4 YAP1 ODAD1 CBY2 FAM167A PTPN23 SF1 ARHGEF15 PCNT

2.16e-06256909int:CEP55
InteractionNEFM interactions

LURAP1L DLG5 YAP1 DISC1 IQCB1 FAM167A DNAH9 KIF7

2.16e-06190908int:NEFM
InteractionCNTRL interactions

DLG5 NAA15 TCHP FAM167A CCDC85C CEP131 KIF7 PCNT

2.43e-06193908int:CNTRL
InteractionKRT18 interactions

KRT3 KRT4 DLG5 TCHP KIAA1217 IQCB1 PDE4DIP CEP131 ALDH3A2 KIF7 PCNT

2.62e-064199011int:KRT18
InteractionLATS1 interactions

KRT4 DLG5 TCHP YAP1 CBY2 KIAA1217 CCDC85C CEP131 DMPK KIF7 PCNT

4.19e-064409011int:LATS1
InteractionFAM167A interactions

NDE1 FAM167A HOOK2 VPS16 ANAPC5 IQGAP3

4.50e-0696906int:FAM167A
InteractionKRT19 interactions

KRT3 KRT4 DLG5 TCHP YAP1 CEP131 PAWR KIF7 PCNT

4.75e-06282909int:KRT19
InteractionODF2 interactions

DLG5 ABLIM1 TCHP ODAD1 CCDC85C CEP131 KIF7

6.90e-06158907int:ODF2
InteractionCEP128 interactions

DLG5 ABLIM1 NDE1 TCHP IQCB1 CCDC85C CEP131 PAWR KIF7

7.22e-06297909int:CEP128
InteractionANAPC2 interactions

DLG5 IQCB1 CCDC85C CEP131 ALDH3A2 ANAPC5 KIF7 PCNT

1.00e-05234908int:ANAPC2
InteractionAMOT interactions

DLG5 TCHP YAP1 DISC1 UBR4 CEP131 RBCK1 KIF7 PCNT

1.07e-05312909int:AMOT
InteractionKRT38 interactions

KRT3 KRT4 DISC1 CCDC85C IQGAP3 KIF7 PCNT

1.20e-05172907int:KRT38
InteractionCEP290 interactions

TCHP DISC1 IQCB1 CEP131 PAWR KIF7 PCNT

1.56e-05179907int:CEP290
InteractionCCDC198 interactions

CBY2 PDE4DIP HOOK2 IQGAP3

1.75e-0535904int:CCDC198
InteractionMAPRE1 interactions

DLG5 ABLIM1 NDE1 KIAA1217 IQCB1 PDE4DIP CEP131 HOOK2 ITPRID2 ALDH3A2 PCNT

1.80e-055149011int:MAPRE1
InteractionPXN interactions

DLG5 ABLIM1 KIAA1217 CCDC85C PTPN23 CEP131 IQGAP3 KIF7 PCNT

1.84e-05334909int:PXN
InteractionCEP44 interactions

CCDC185 TCHP CBY2 DISC1 FAM167A CCDC85C PCNT

2.21e-05189907int:CEP44
InteractionPCM1 interactions

DLG5 TCHP DISC1 KIAA1217 IQCB1 CCDC85C CEP131 ITPRID2 KIF7 PCNT

2.38e-054349010int:PCM1
InteractionNIN interactions

TCP10L NDE1 TCHP KIAA1217 IQCB1 CCDC85C CEP131 KIF7 PCNT

3.24e-05359909int:NIN
InteractionLURAP1 interactions

KRT3 DLG5 CCDC185 YAP1 KIF3A KIF7

3.45e-05137906int:LURAP1
InteractionTPTE2 interactions

UBR5 CEP131 ITPRID2 KIF7 PCNT

3.71e-0584905int:TPTE2
InteractionLATS2 interactions

TCHP UBR5 YAP1 IQCB1 CCDC85C CEP131 DMPK ANAPC5

4.55e-05289908int:LATS2
InteractionFGL2 interactions

ITPRID2 KIF7 PCNT

4.62e-0516903int:FGL2
InteractionCEP89 interactions

DLG5 ABLIM1 TCHP CCDC85C CEP131 KIF7

5.11e-05147906int:CEP89
InteractionSTX11 interactions

NDE1 UBR5 DISC1 UBR4 ITPRID2 KIF7

5.11e-05147906int:STX11
InteractionMAPRE3 interactions

DLG5 ABLIM1 KIAA1217 PDE4DIP CEP131 KIF7 PCNT

7.70e-05230907int:MAPRE3
InteractionNDC80 interactions

DLG5 NDE1 TCHP KIAA1217 CCDC85C CEP131 KIF7 PCNT

7.78e-05312908int:NDC80
InteractionSASS6 interactions

DLG5 TCHP UBR4 CEP131 KIF7 PCNT

7.91e-05159906int:SASS6
InteractionDUSP16 interactions

DISC1 IQCB1 PTPN23 ITPRID2 VPS16 ANAPC5 PCNT

9.29e-05237907int:DUSP16
InteractionARNT2 interactions

RIMBP3 NDE1 YAP1 PDE4DIP RBCK1

9.40e-05102905int:ARNT2
InteractionAP4E1 interactions

NDE1 DISC1 LAMA1 HOOK2

9.92e-0554904int:AP4E1
InteractionUHMK1 interactions

CNOT6L UBR5 UBR4 KIF3A

9.92e-0554904int:UHMK1
InteractionPCNT interactions

TCP10L TCHP ODAD1 DISC1 SPTBN2 CEP131 PCNT

1.03e-04241907int:PCNT
InteractionCALM1 interactions

DOCK3 PDF UBR5 YAP1 DISC1 UBR4 IQCB1 PDE4DIP ITPRID2 IQGAP3 PCNT

1.07e-046269011int:CALM1
InteractionC1orf87 interactions

UBR4 PDE4DIP PCNT

1.08e-0421903int:C1orf87
InteractionZUP1 interactions

KRT3 KRT4 UBR5 UBR4 VPS16 KIF7

1.30e-04174906int:ZUP1
InteractionVPS33A interactions

RBSN TCHP CEP131 HOOK2 VPS16 KIF3A KIF7

1.39e-04253907int:VPS33A
InteractionKRT35 interactions

KRT3 KRT4 CCDC185 TCHP LAMA1

1.40e-04111905int:KRT35
InteractionCALM3 interactions

YAP1 UBR4 IQCB1 CEP131 ITPRID2 LMTK3 IQGAP3 PCNT

1.50e-04343908int:CALM3
InteractionCEP63 interactions

TCHP DISC1 CCDC85C CEP131 KIF7 PCNT

1.52e-04179906int:CEP63
InteractionCPAP interactions

ABLIM1 TCHP CCDC85C CEP131 KIF7 PCNT

1.66e-04182906int:CPAP
InteractionNAA11 interactions

NAA15 PDE4DIP ANAPC5 NAA16

1.70e-0462904int:NAA11
InteractionHAUS1 interactions

KRT3 ODAD1 CBY2 PDE4DIP FAM167A HOOK2

1.71e-04183906int:HAUS1
InteractionNDE1 interactions

TCP10L SPTBN4 NDE1 DISC1 FAM167A

1.80e-04117905int:NDE1
InteractionMTMR7 interactions

MTMR4 UBR5 VPS16 ALDH3A2

1.93e-0464904int:MTMR7
InteractionCEP135 interactions

DLG5 NDE1 TCHP CEP131 ALDH3A2 KIF7 PCNT

2.17e-04272907int:CEP135
InteractionKRT16 interactions

KRT3 KRT4 TCHP YAP1 IQCB1 KIF7

2.55e-04197906int:KRT16
InteractionAGBL4 interactions

DISC1 CEP131 KIF7 FARP2

2.72e-0470904int:AGBL4
InteractionCCDC6 interactions

TCP10L RIMBP3 TCHP YAP1 KIAA1217 IQCB1 PDE4DIP

2.95e-04286907int:CCDC6
InteractionFAM184A interactions

TCHP CEP131 KIF7 PCNT

3.03e-0472904int:FAM184A
InteractionTNIK interactions

ABLIM1 NDE1 DISC1 KIAA1217 SPTBN2 PDE4DIP ZMYM2 KIF7

3.05e-04381908int:TNIK
InteractionTRIM52 interactions

DISC1 IQCB1 CEP131 IQGAP3 PCNT

3.26e-04133905int:TRIM52
InteractionYWHAH interactions

DLG5 ABLIM1 RBSN PHLDB1 MTMR4 NDE1 YAP1 KIAA1217 IQCB1 CCDC85C CEP131 ITPRID2 KIF7 PCNT

3.63e-0411029014int:YWHAH
InteractionRNF6 interactions

ABLIM1 CBY2 PAWR HOOK2

3.73e-0476904int:RNF6
InteractionPARD3 interactions

DLG5 TCHP YAP1 KIAA1217 CCDC85C KIF3A KIF7

3.78e-04298907int:PARD3
InteractionUBE2S interactions

NAA15 UBR5 UBR4 ANAPC5 RBCK1

3.86e-04138905int:UBE2S
InteractionARC interactions

SPTBN4 NDE1 ITPRID2

3.89e-0432903int:ARC
InteractionYWHAG interactions

DLG5 ABLIM1 PHLDB1 MTMR4 NAA15 NDE1 YAP1 DISC1 CCDC85C CEP131 PAWR ITPRID2 KIF13A KIF7 FARP2

3.95e-0412489015int:YWHAG
InteractionELMO3 interactions

DOCK3 DOCK5 UBR4

4.66e-0434903int:ELMO3
InteractionKRT25 interactions

KRT3 KRT4 YAP1

5.08e-0435903int:KRT25
InteractionMOB4 interactions

DLG5 ABLIM1 UBR5 UBR4 ARHGEF15

5.65e-04150905int:MOB4
InteractionSAV1 interactions

DLG5 YAP1 FAM167A CEP131 KIF7

5.82e-04151905int:SAV1
InteractionCCDC22 interactions

NDE1 YAP1 ODAD1 DISC1 FAM167A

6.00e-04152905int:CCDC22
InteractionLTBR interactions

TCHP IQCB1 CEP131 RBCK1

6.51e-0488904int:LTBR
InteractionFAM161A interactions

LURAP1L CCDC185 CBY2 PDE4DIP HOOK2

6.75e-04156905int:FAM161A
InteractionZYX interactions

DOCK3 DLG5 ABLIM1 YAP1 KIAA1217 PTPN23 PCNT

6.80e-04329907int:ZYX
InteractionCCDC8 interactions

ABLIM1 PHLDB1 UBR5 SPTBN2 CEP131 PAWR ITPRID2 SF1 KIF7 PCNT

6.85e-046569010int:CCDC8
InteractionKIAA0753 interactions

ABLIM1 TCHP CEP131 KIF7 PCNT

6.94e-04157905int:KIAA0753
InteractionPEA15 interactions

MTIF3 IQCB1 PDE4DIP ABCD4

7.09e-0490904int:PEA15
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF13A KIF17 KIF3A KIF7

9.08e-0646524622
GeneFamilyEF-hand domain containing|Spectrins

SPTBN4 SPTBN2

1.69e-0475221113
GeneFamilyUbiquitin protein ligase E3 component n-recognins

UBR5 UBR4

1.69e-047522785
GeneFamilyN(alpha)-acetyltransferase subunits|GCN5 related N-acetyltransferases

NAA15 NAA16

5.26e-0412522660
GeneFamilyDyneins, axonemal

DNAH9 DNAH11

1.07e-0317522536
GeneFamilyKeratins, type II

KRT3 KRT4

2.72e-0327522609
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

SPTBN4 PHLDB1 SPTBN2 FARP2

2.89e-03206524682
GeneFamilyZinc fingers FYVE-type|Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors

RBSN MTMR4

3.58e-033152281
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DLG5 ABLIM1 CCDC185 KIAA1217 SUN1 PAWR

1.84e-061799166e965e424eebef50f0202cff75f458be395cfca1
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 UBR5 ZMYM2 KIF13A ANAPC5 FARP2

2.44e-061889166468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 UBR5 ZMYM2 KIF13A ANAPC5 FARP2

2.44e-061889167a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 UBR5 ZMYM2 KIF13A ANAPC5 FARP2

2.44e-061889169cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

ABLIM1 YAP1 KIAA1217 PAWR DNAH9 DNAH11

3.10e-06196916af4cdc61830685a888a1209826c23bcf54a43084
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

ABLIM1 YAP1 KIAA1217 PAWR DNAH9 DNAH11

3.10e-061969166d02d494196e3f857d53eea46d9419690d43beca
ToppCelllymphoid-T_cell-pro-T_cell|T_cell / Lineage, cell class and subclass

DENND5B GPR20 TEKT5 CTSG IQGAP3

1.94e-0516091566fe86d2f37983761141e5bb3de127f0b4bb0951
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF781 SPTBN2 IQCB1 GZMM IQGAP3

2.12e-05163915453e0bb292baca2938d24582fedfd6a8bb1e78e9
ToppCell10x5'-blood-Lymphocytic_B-ABC_aged-B_memory|blood / Manually curated celltypes from each tissue

DENND5B SMIM14 FAM167A PAWR FARP2

2.19e-051649150424b23fc540580e7c15c50a7a03dff7c25014fa
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-Activated_CD8_T|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK3 CNOT6L DISC1 GZMM KIF3A

2.19e-0516491524fdea5113d92b96f56b06dd2449910a3c785e69
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-1|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DENND5B SMIM14 PAWR DNAH11 FARP2

3.24e-05178915812e261d9cbdc74fafe3c5c3422151c1cfacb22d
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABLIM1 CNOT6L IQCB1 GZMM FAM167A

3.24e-05178915f94e306b9550f3d1b5de0bb806790c17823d439e
ToppCellfacs-Marrow-B-cells-18m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTBN4 ODAD1 DISC1 ALDH3A2 KIF3A

3.41e-051809157368ab31c3273374ef260f0d710d4eea83cbc4a2
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

DPEP2 GZMM RASSF4 ANAPC5 SNX19

4.31e-05189915160963355256f7c0f2138da80c90de478f5a9fe8
ToppCelldroplet-Tongue-nan-24m-Epithelial-filiform|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHLDB1 PDE4DIP RASSF4 DMPK KIF13A

4.41e-0519091586ab845a7fae2111c0b01e1aec235e19c4c0ef5c
ToppCellLAM-Epithelial-AT1|Epithelial / Condition, Lineage and Cell class

KRT4 ABLIM1 FAM167A ITPRID2 ALDH3A2

4.53e-051919153457e15d1e9b36a78363d46b320c4ec46b40290a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABLIM1 CNOT6L GZMM SF1 NAA16

4.53e-05191915696921a4f160b6b55698652488ed781e855e5e51
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LURAP1L KRT3 GPR20 CIB4 PAWR

4.64e-051929158ad6678df89175c5a4a835c8566f1552df3c996e
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LURAP1L KRT3 GPR20 CIB4 PAWR

4.64e-051929152f5378ea0b2fb2f672a36585d375f675983363a1
ToppCellASK440-Epithelial-Secretory|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

KRT4 ABLIM1 KIAA1217 PAWR ALDH3A2

4.76e-0519391550e98d91697c7af6a3de39e52edde6dd2b67b512
ToppCelldroplet-Tongue-TONGUE-1m-Epithelial-suprabasal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABLIM1 PHLDB1 SPTBN2 ITPRID2 DMPK

4.87e-05194915a3adcdc8b87332e8beb9bcd70cf36424af10633d
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

YAP1 KIAA1217 PAWR DNAH9 DNAH11

4.99e-05195915fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

YAP1 KIAA1217 PAWR DNAH9 DNAH11

4.99e-05195915eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-ciliated_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

LURAP1L KRT4 YAP1 KIAA1217 LMTK3

5.12e-05196915b246e482f012dd9782b49c2a953acedfa3c1139d
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-ciliated_cell-Epi-Ciliated|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

LURAP1L KRT4 YAP1 KIAA1217 LMTK3

5.12e-05196915808c0a7d1889a8f3508ed9790c6dc7ec16bbc840
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK3 TTC7B DPEP2 DISC1 RASSF4

5.37e-051989150b41b3d6c2db795320e8b65d40d85fb8b618cc34
ToppCellHealthy_donor-Non-classical_Monocyte|World / disease group, cell group and cell class (v2)

DOCK5 GPR20 SLC24A4 DPEP2 PIK3CG

5.37e-051989158a97c8b2a43e6d1e669ce18752841e2006744bd9
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KRT4 ABLIM1 ODAD1 DNAH9 DNAH11

5.37e-05198915d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KRT4 ABLIM1 UBE2G1 YAP1 SUN1

5.50e-051999155a1557fe35aa48080d4967e8724bf27f9585a5fb
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KRT4 ABLIM1 UBE2G1 YAP1 SUN1

5.50e-051999150a657475b92aa3a713da62da364525249fdc3886
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

UBR5 KIAA1217 ITPRID2 ARHGEF15 PCNT

5.63e-05200915dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
Diseasespinocerebellar ataxia type 5 (implicated_via_orthology)

SPTBN4 SPTBN2

4.90e-054852DOID:0050882 (implicated_via_orthology)
DiseaseMental Retardation, Psychosocial

NAA15 DISC1 LAMA1 ZMYM2 KIF7

5.23e-05139855C0025363
DiseaseProfound Mental Retardation

NAA15 DISC1 LAMA1 ZMYM2 KIF7

5.23e-05139855C0020796
DiseaseMental deficiency

NAA15 DISC1 LAMA1 ZMYM2 KIF7

5.23e-05139855C0917816
DiseaseIntellectual Disability

NAA15 DISC1 LAMA1 ZMYM2 PTPN23 ALDH3A2 KIF7

3.12e-04447857C3714756
DiseasePrimary Ciliary Dyskinesia

ODAD1 DNAH9 DNAH11

3.41e-0447853C4551720
Diseasecongenital heart disease (implicated_via_orthology)

NAA15 UBE2G1 NAA16

1.05e-0369853DOID:1682 (implicated_via_orthology)
DiseaseLimb Deformities, Congenital

HOXA11 HOXD11

1.08e-0317852C0206762
Diseasemajor depressive disorder (is_marker_for)

DISC1 PAWR

1.08e-0317852DOID:1470 (is_marker_for)
Diseaseintellectual disability (implicated_via_orthology)

NAA15 UBR4 NAA16

1.34e-0375853DOID:1059 (implicated_via_orthology)
DiseaseStomach Carcinoma

TCHP UBR5

1.66e-0321852C0699791
Diseaseurate measurement, bone density

DOCK5 GIPR YAP1 DNAH9 SNX19 RBCK1 DNAH11

2.08e-03619857EFO_0003923, EFO_0004531
Diseasealkaline phosphatase measurement

DLG5 PHLDB1 YAP1 DPEP2 IQCB1 FAM167A KIF17 KIAA1614 FARP2

2.59e-031015859EFO_0004533
DiseaseBone Diseases, Developmental

HOXD11 KIF3A

2.75e-0327852C0005941
Diseaseglucose tolerance test

GIPR KCNQ1

2.75e-0327852EFO_0004307

Protein segments in the cluster

PeptideGeneStartEntry
MQLLQVRTTNTLRRL

nan

1

Q8NBF4
MTLERERRLLLRQSQ

CCDC185

296

Q8N715
LLRRRQLQEEQLMKL

ABLIM1

596

O14639
LATQRRLEERQRQQM

BAZ2A

801

Q9UIF9
RVLRELDLQVLDTRM

GZMM

161

P51124
QGRQRRVRAMQLLLT

GPR20

231

Q99678
RMNILIREIRISLEQ

DNAH11

4291

Q96DT5
RFRLQQLEALRRMVQ

ALDH3A2

21

P51648
AFLDQRLILERLQVM

GIPR

126

P48546
TRLRMLLQNILRQTE

ARHGEF15

561

O94989
RRLQRLLQTQRELMS

ABCD4

251

O14678
LLRNRRQMEVISLRL

DISC1

341

Q9NRI5
RMASRIIINERQRLI

SLC24A4

341

Q8NFF2
RERQENLRLVRLMQD

PAWR

281

Q96IZ0
SLRNRDVILAIQQMI

OR5M10

291

Q6IEU7
DLQREQLQMLREREL

RBSN

516

Q9H1K0
LRLTMLQRLEQLVEA

RASSF4

306

Q9H2L5
ESQREVLRLQRQLML

RIMBP3B

531

A6NNM3
ESQREVLRLQRQLML

RIMBP3C

531

A6NJZ7
MANRLQRGDRSRLLL

PCDHGA11

1

Q9Y5H2
MRDQRVSLEQQLREL

PTPN23

566

Q9H3S7
AVSLMERRRLNQLLL

ANAPC5

51

Q9UJX4
NLMVRIKELQRRLDQ

KCNQ1

551

P51787
QQRCLDLERQLMLLS

HOOK2

191

Q96ED9
QELQRERQLRMLEDL

RBCK1

141

Q9BYM8
SEIIELNRMIQRLRA

KRT3

416

P12035
AELNRMIQRLRAEIE

KRT4

356

P19013
RVERNRLLLQEMLNV

KIAA1614

296

Q5VZ46
QLLMSLREDVTRNLL

LMTK3

861

Q96Q04
GLMRDVNRRLQQHLL

CCDC85C

51

A6NKD9
IRLMDERDLRLVQRN

MTIF3

106

Q9H2K0
MTGLQILQERQRLRE

MTIF3

131

Q9H2K0
ILRDLSLLQIQMRDL

NAA16

116

Q6N069
VENLSIQLRLMTRER

DLG5

146

Q8TDM6
MLRRENGQLLRERNL

DLG5

246

Q8TDM6
ALERQRLEMDRQLTL

KIF7

1141

Q2M1P5
AQILRERMELLQLAQ

JAKMIP3

791

Q5VZ66
RLQLSRMLNLTDRQV

HOXA11

271

P31270
ELQRLTQRLVQVMRR

PDF

91

Q9HBH1
ENIRQLSRELRLQML

KIF3A

576

Q9Y496
LSRELRLQMLIIDNF

KIF3A

581

Q9Y496
MQLRRVLHDIRNSLQ

ITPRID2

911

P28290
RLRDSQRLENMDRLL

ODAD1

46

Q96M63
REMLNSRRAQELALL

PCNT

281

O95613
QQRELEAMRQRLLSA

PCNT

2971

O95613
MSAEVRLRRLQQLVL

DMPK

1

Q09013
VQRRLDIALRNLLAM

IQGAP3

1111

Q86VI3
ILRDLSLLQIQMRDL

NAA15

116

Q9BXJ9
VEQLRRQVRELQMRL

MTMR4

1036

Q9NYA4
MLRQVQNRAITLRRE

MORC2

331

Q9Y6X9
LRTLQLQRNQLRMLE

PODNL1

431

Q6PEZ8
LQLLREMRQALQALL

CBY2

356

Q8NA61
LQLLRGDMEQIRREN

DOCK3

381

Q8IZD9
QLIMERLLRRINRTV

DOCK5

926

Q9H7D0
RLQLSRMLNLTDRQV

HOXD11

296

P31277
LRDRMTVNSLIRILQ

DENND5B

1241

Q6ZUT9
NLRATDVRLMRQLLV

LURAP1L

106

Q8IV03
QLQLQRQRAMRLSRE

IQCB1

351

Q15051
LRLTLEQIDLIRRMC

DPEP2

146

Q9H4A9
QNDIMLLQLSRRVRR

CTSG

106

P08311
RMNILTREIQRSLRE

DNAH9

4261

Q9NYC9
HQRIGDILLRNMRQL

FARP2

616

O94887
AMLLLQRALAQQRDL

CEP131

586

Q9UPN4
TIRRQERDSMLLQQL

KIF17

846

Q9P2E2
RLQDQQLARQLMRLR

FAM167A

131

Q96KS9
RLMYERELEQLRQQL

KIF13A

621

Q9H1H9
TLLMDRIRLQELAFQ

TCP11X2

216

Q5H9J9
NMELREKLRALQLQR

TCP10L

86

Q8TDR4
ESQREVLRLQRQLML

RIMBP3

531

Q9UFD9
LRLQRIRTLNADLMT

LAMA1

226

P25391
EILIRRQNTLRESMR

SLC9A4

626

Q6AI14
EHAMRRLINLLRQSQ

SMIM14

16

Q96QK8
RSVAELRLQLQQMRQ

KIAA1217

651

Q5T5P2
LRLRETQDTLQLLVM

TEKT5

431

Q96M29
QVRLLKENQMLRRLL

SPATC1L

21

Q9H0A9
DLQRIILRLLNSDDM

CIB4

121

A0PJX0
MVSLRELLLNNNLLR

CNOT6L

101

Q96LI5
DDLRQDMLILQILRI

PIK3CG

836

P48736
AELRRRLLELRMQQN

URGCP

526

Q8TCY9
LRQMVAARRERLLLN

SPTBN2

516

O15020
EDQMRLLRLQRRLED

VPS16

671

Q9H269
ERLRLKQQELLRQAM

YAP1

316

P46937
RDLRQALVVLRNQEM

SPTBN4

1206

Q9H254
ELEELRLSMNLQERR

TCHP

101

Q9BT92
LQLERAREAELQMLL

TCHP

336

Q9BT92
MERLERQRLETILNL

PHLDB1

606

Q86UU1
RQLEREINRTIQMII

SNX19

96

Q92543
LDRNTLENMLVRVLL

ZMYM2

1346

Q9UBW7
NLRMTIARQLAEILL

TTC7B

256

Q86TV6
DLQTMLRDLQLQILR

SUN1

546

O94901
MLLERLLQTLPQLRN

UBR4

2976

Q5T4S7
MTELQSALLLRRQLA

UBE2G1

1

P62253
QHLLNTRELILMRNL

ZNF781

186

Q8N8C0
QNDLRKMQLRELARL

SF1

236

Q15637
RDRDLLIQQTMRQLN

UBR5

2246

O95071
LCQRLQRKERMLQDL

PDE4DIP

616

Q5VU43
RQQLLLMLEGLVDER

PDE4DIP

856

Q5VU43
NRDLLSENNRLRMEL

NDE1

61

Q9NXR1