Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionglycosylceramidase activity

GBA3 LCT

2.81e-062342GO:0017042
GeneOntologyMolecularFunctionglucosylceramidase activity

GBA3 LCT

1.68e-054342GO:0004348
GeneOntologyMolecularFunctiongalactosylceramidase activity

GBA3 LCT

2.81e-055342GO:0004336
GeneOntologyMolecularFunctionbeta-glucosidase activity

GBA3 LCT

4.20e-056342GO:0008422
GeneOntologyMolecularFunctionglucosidase activity

GBA3 LCT

2.91e-0415342GO:0015926
GeneOntologyMolecularFunctionhydrolase activity, hydrolyzing O-glycosyl compounds

ENGASE GBA3 LCT

7.10e-04103343GO:0004553
GeneOntologyMolecularFunctionfibroblast growth factor binding

FIBP PTPRZ1

9.62e-0427342GO:0017134
GeneOntologyMolecularFunctionhydrolase activity, acting on glycosyl bonds

ENGASE GBA3 LCT

1.87e-03144343GO:0016798
DomainGlyco_hydro_1_N_CS

GBA3 LCT

1.81e-054332IPR033132
DomainGlut_rich_SH3-bd

SH3BGR SH3BGRL2

1.81e-054332IPR006993
DomainSH3BGR

SH3BGR SH3BGRL2

1.81e-054332PF04908
DomainGlyco_hydro_1_AS

GBA3 LCT

1.81e-054332IPR018120
DomainGLYCOSYL_HYDROL_F1_2

GBA3 LCT

3.02e-055332PS00653
DomainGLYCOSYL_HYDROL_F1_1

GBA3 LCT

3.02e-055332PS00572
DomainGlyco_hydro_1

GBA3 LCT

3.02e-055332PF00232
DomainGlyco_hydro_1

GBA3 LCT

3.02e-055332IPR001360
Domain-

GBA3 LCT

1.74e-03353323.20.20.80
DomainGlyco_hydro_catalytic_dom

GBA3 LCT

2.05e-0338332IPR013781
DomainGlycoside_hydrolase_SF

GBA3 LCT

3.94e-0353332IPR017853
Pubmed

Deglycosylation by small intestinal epithelial cell beta-glucosidases is a critical step in the absorption and metabolism of dietary flavonoid glycosides in humans.

GBA3 LCT

9.28e-07234212594539
Pubmed

The inositol phosphatase SHIP-1 inhibits NOD2-induced NF-κB activation by disturbing the interaction of XIAP with RIP2.

DAB1 NOD2

2.59e-05834222815893
Pubmed

Platelet proteome analysis reveals integrin-dependent aggregation defects in patients with myelodysplastic syndromes.

FIBP PLEK

2.97e-042634223382103
Pubmed

Modulation of the combinatorial code of odorant receptor response patterns in odorant mixtures.

OR5AC1 OR11G2

3.21e-042734232061665
Pubmed

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.

MUC19 NOD2

3.45e-042834218587394
Pubmed

Genetic risk profiling and prediction of disease course in Crohn's disease patients.

LCT NOD2

3.45e-042834219422935
Pubmed

Recapitulating early development of mouse musculoskeletal precursors of the paraxial mesoderm in vitro.

GREB1L ABCA1

3.97e-043034229555813
Cytoband14q11.2

OR11G2 AJUBA OR11H6

3.24e-0418034314q11.2
CytobandEnsembl 112 genes in cytogenetic band chr14q11

OR11G2 AJUBA OR11H6

1.90e-03332343chr14q11
GeneFamilyOlfactory receptors, family 11

OR11G2 OR11H6

3.20e-0423212159
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GREB1L RP1 LGSN HYDIN

7.42e-0616534482530f96aaefe28a13bad0474bbad043f127a86c
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GREB1L RP1 LGSN HYDIN

7.42e-061653440c714e852f912b5749de4cb0895406673979b2e6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS16 GREB1L ASIC5 HYDIN

1.09e-051823445e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DAB1 ADAMTS16 GREB1L HYDIN

1.14e-0518434430fddbc9696476d4d7f08e53f84ea994a4ed873a
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DAB1 ADAMTS16 GREB1L HYDIN

1.14e-0518434496926efa220f03d0787322c9519bb9e8f64f74d0
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TMEM67 RP1 PTPRZ1 HYDIN

1.38e-05193344ea345d34440b25f65358a53dc72831998d1c3620
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM67 RP1 LGSN HYDIN

1.49e-0519734474a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellPosterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PTGR1 EEF1AKMT3 SH3BGR

1.04e-04120343a320799ab5f2ce872e038b15841a23174c5436e8
ToppCellfacs-Heart-RV-18m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HYDIN ZMYND12 SLC4A1

1.44e-04134343d101e16cb87ff72c81324406fe7e3d70ed8f45df
ToppCellfacs-Heart-RV-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HYDIN ZMYND12 SLC4A1

1.44e-041343430c63c8b3c748d29c59fcb27d03276ba4f6a0d6b2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS16 GREB1L HYDIN

1.51e-0413634382b1d6d839c0d0c68e0960549f688138479defcc
ToppCellPosterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Acta2Rgs5.Fos_(Mural.Acta2Rgs5.Fos)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PTGR1 EEF1AKMT3 SH3BGR

1.54e-041373435ca712230a888403769547c2e03760131abaa4cf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS16 GREB1L HYDIN

1.54e-041373430aa4e14b32da0cda677cc0ed6ae470f6ecd77bea
ToppCellPosterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Acta2Rgs5.Fos_(Mural.Acta2Rgs5.Fos)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PTGR1 EEF1AKMT3 SH3BGR

1.54e-041373432282caba7a59d7c0d7a3de8b04a94a24fa01d10c
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Pi16_(Pi16)|Thalamus / BrainAtlas - Mouse McCarroll V32

RP1 CCM2L NOD2

1.71e-0414234358bfff3284ae21150e4619511bd58622c16c5dde
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Pi16_(Pi16)--|Thalamus / BrainAtlas - Mouse McCarroll V32

RP1 CCM2L NOD2

1.71e-041423435fd737c1fee9d97aee8955f1bf378ead3fce138d
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Pi16_(Pi16)-|Thalamus / BrainAtlas - Mouse McCarroll V32

RP1 CCM2L NOD2

1.71e-0414234316f9945e835c3506b12d904778560d065a50f059
ToppCellfacs-Heart-LV-24m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 LCT SLC4A1

1.75e-041433438f82b3c3331f20c6ded36dbfb9a48dbd9f099f93
ToppCellfacs-Heart-LV-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 LCT SLC4A1

1.75e-0414334352832321cc848739ff6483f467d57c50c8b7395c
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

EXOSC10 SH3BGR ZMYND12

1.86e-04146343bb7bf20245d93c8812920dd0debbf1ed00add378
ToppCellCiliated_cells-A-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

RP1 LGSN HYDIN

2.05e-041513439d03ce73af15ef40c592d19b36aff46bebc14c40
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB1 ADAMTS16 SH3BGR

2.18e-041543431e32969bee810adaf2d560f0824a16227df513d8
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RP1 PTPRZ1 HYDIN

2.22e-041553435f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RP1 PTPRZ1 HYDIN

2.22e-041553430944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS16 RP1 MEX3D

2.39e-04159343c186bf05c61fac348cf41973827cced83fafd58a
ToppCellfacs-Lung-EPCAM-3m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GREB1L PLEK NOD2

2.44e-04160343b73f07a0088936fbc3656a05710a67f38b4ae551
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 PTPRZ1 HYDIN

2.44e-04160343c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellPND01-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DAB1 PTGR1 SH3BGRL2

2.44e-04160343b4844a8c7755a2b2868019791d8d224154973445
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GREB1L PLEK NOD2

2.44e-04160343b88876a58fea2066468e74dcc439c8561130a910
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 PTPRZ1 HYDIN

2.44e-0416034325c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellPND01-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DAB1 PTGR1 SH3BGRL2

2.44e-0416034301ae730e9d0d05f3277f862f0c09bafb32b89db5
ToppCellPND01-Epithelial-Epithelial_Airway-Neurosecretory|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DAB1 PTGR1 SH3BGRL2

2.44e-041603436de9e7be1d860d82d503bfbc779e72f072a6efc3
ToppCellCiliated_cells-A-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

RP1 LGSN HYDIN

2.57e-0416334343194c6127df1ce3d29242f719645de3c11fd7c0
ToppCellCiliated_cells-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

TMEM67 RP1 HYDIN

2.62e-04164343fd30c55d0d75ef8b9396435d836187168095152b
ToppCellfacs-Thymus-nan-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 SULF2 PLEK

2.81e-04168343d72cd8238fa793bb3e4add4c59eaaaadcea9930d
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RP1 HYDIN ZMYND12

2.81e-04168343fa7c0303918cea04e3f4c4f3cb079be19004d214
ToppCellfacs-Thymus-nan-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 SULF2 PLEK

2.81e-04168343d2afc097ae1243574210be6a751685f949ea941a
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RP1 HYDIN ZMYND12

2.81e-041683437edcab103c69e928d5c19a0d218ffb3ae32f9e70
ToppCellfacs-Thymus-nan-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 SULF2 PLEK

2.81e-04168343c34c52165485f612add7a3e35a175d5a6e365e7c
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM67 RP1 HYDIN

2.86e-0416934314aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L5_RORB_LINC01202|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS16 SULF2 ASIC5

2.91e-0417034387cac555f16b6c2ef3d1b3a00f992d8bf2237b50
ToppCellCiliated_cells-A-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

RP1 LGSN HYDIN

2.91e-041703438b7ef1464ea589886b575ebad5447b085cbdcdba
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS16 SULF2 ASIC5

3.01e-0417234341ddfb316429efef5f3fa0b0621ced383d9206f0
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L5_RORB_LINC01202|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS16 SULF2 ASIC5

3.01e-0417234318bdf34e1b94dcb1daf00c533e3ce1a8d67fcc0e
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCA1 SULF2 PLEK

3.01e-04172343f0e767a20d93e546ce278db67dbd779cc68af533
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SULF2 CCM2L AJUBA

3.01e-04172343c056d44e2e130ceccadfcdceb192a7f095d779c8
ToppCelldroplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS16 RP1 AJUBA

3.11e-04174343a0ccda8fd6f55251cdeff24cf66e72e4a31d2104
ToppCelldroplet-Lung-LUNG-30m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB1 PTPRZ1 HYDIN

3.22e-041763435201f003192c033655ba47f0faf8c47a96eae03d
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L5_RORB_LINC01202|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS16 SULF2 ASIC5

3.27e-04177343b6476a91abd06b8271b4d0ad7431d24b44022b47
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SULF2 ASIC5 PTPRZ1

3.38e-04179343b35a7f8115c997c390201da01d7cb10b10769aec
ToppCellASK454-Epithelial-Ciliated|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

RP1 EEF1AKMT3 HYDIN

3.38e-04179343f21919ef9d3d984e2925ef3d24f89e20fe265dcd
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DAB1 PTPRZ1 MEX3D

3.44e-04180343c72f15763ba707189e29c85db533557f01c7fdb1
ToppCellE18.5-samps-Mesenchymal-Pericyte|E18.5-samps / Age Group, Lineage, Cell class and subclass

ADAMTS16 AJUBA PTPRZ1

3.44e-041803430b1d370db64862fe1c7ea0ffaf06d03ec82e6e70
ToppCell368C-Epithelial_cells-Epithelial-F_(Ciliated)-|368C / Donor, Lineage, Cell class and subclass (all cells)

RP1 LGSN HYDIN

3.50e-041813435a4574f1bfd0b4ca78da7effda43420857e17296
ToppCelldroplet-Lung-LUNG-30m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SULF2 PLEK SH3BGRL2

3.50e-041813438fcdab61fad2efd324d2b27c58f5a594f1dc15de
ToppCell368C-Epithelial_cells-Epithelial-F_(Ciliated)|368C / Donor, Lineage, Cell class and subclass (all cells)

RP1 LGSN HYDIN

3.50e-04181343a4e891603645f694687e68e585744ddc1a3c8697
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RP1 LGSN HYDIN

3.50e-04181343dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SULF2 PLEK SH3BGRL2

3.55e-04182343be48ce85991bceeff938ba080e6bf9cc62176b05
ToppCellCiliated_cells-B-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

TMEM67 RP1 HYDIN

3.55e-04182343e44c4810dc7d51a76b86d7623f8e4c4d8b4bf2fc
ToppCellCiliated_cells-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

TMEM67 RP1 HYDIN

3.55e-04182343e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCelldroplet-Heart-4Chambers-18m-Neuronal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB1 ADAMTS16 ZMYND12

3.61e-041833432df1611c8acccb2a6f233d3d68bd9df2381a7278
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS16 AJUBA PTGR1

3.67e-0418434310706441e7695212f95689414f31e8082b5eaf0a
ToppCell3'-Adult-SmallIntestine-Epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DAB1 LCT PTGR1

3.67e-04184343ed7a8e79e5723a5f5a03f542203d9e50bdef5f50
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SULF2 PLEK SH3BGRL2

3.67e-041843438fa30789c9d583188667cf375d2218e392dd40bc
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS16 AJUBA PTGR1

3.67e-041843434bb0976a75126ad2b3deb5d2229f0716fafe200e
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SULF2 ASIC5 PTPRZ1

3.73e-04185343a1b2525da018abe458908cab7268bd403ee98d92
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCA1 SULF2 SH3BGRL2

3.73e-041853434bee178ede12f56ba5f5bec44a03dc2a62c50137
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TMEM67 RP1 HYDIN

3.73e-041853435e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell390C-Epithelial_cells-Epithelial-F_(Ciliated)|390C / Donor, Lineage, Cell class and subclass (all cells)

RP1 LGSN HYDIN

3.79e-04186343708c5edefe36c91df27cf53c1b5101fb2030cc5a
ToppCell3'-Adult-SmallIntestine-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DAB1 LCT PTGR1

3.79e-04186343bdd9d3a432aab46e733469b362f0064d35c1ac49
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS16 GREB1L HYDIN

3.79e-041863435c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell390C-Epithelial_cells-Epithelial-F_(Ciliated)-|390C / Donor, Lineage, Cell class and subclass (all cells)

RP1 LGSN HYDIN

3.79e-04186343029390c4aaf64e6bcd86124cd4a6dd2e6f3a374b
ToppCell3'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DAB1 LCT PTGR1

3.85e-041873439042bd0f57213a51503d9df2e4dce3209b7772d3
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS16 AJUBA PTGR1

3.85e-041873439aa411ae9b5a923378a5daebb8bb2fc2613f2510
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RP1 SULF2 HYDIN

3.91e-04188343af740fa78542438fdff627ea1f74f4eee43316be
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS16 AJUBA PTGR1

3.91e-04188343842982de2197770f999a70083ed9fca40ac22d79
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS16 AJUBA PTGR1

3.91e-04188343a0815eaf68eedd6e5ec4af520df80a6ab4eb0864
ToppCelldroplet-Lung-immune-endo-depleted-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RP1 HYDIN ZMYND12

3.97e-0418934328c750ac56e3861fe7280e32839a4d8ce8bd8692
ToppCelldroplet-Lung-immune-endo-depleted-3m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RP1 HYDIN ZMYND12

3.97e-04189343efee01edd171bf569267b672fab05c421de6c92d
ToppCellControl-Epithelial-Ciliated|Control / Disease state, Lineage and Cell class

TMEM67 RP1 HYDIN

3.97e-04189343c007fccd08728db3ea99af9da91d67b9b16dabb3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GREB1L PTGR1 SLC4A1

3.97e-04189343532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

TMEM67 RP1 HYDIN

3.97e-041893433e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellEpithelial_cells-Ciliated_cells-B|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

TMEM67 RP1 HYDIN

4.03e-04190343426a4806f6e39d4d57c6746609d30bb3ca62df7d
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

TMEM67 RP1 HYDIN

4.03e-041903439ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCellfacs-Lung-nan-3m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RP1 HYDIN ZMYND12

4.03e-04190343e243b5fbb17b9ec3cc90bbe970c1d30b0fd1c2e1
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

TMEM67 RP1 HYDIN

4.03e-04190343833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCellfacs-Lung-nan-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RP1 HYDIN ZMYND12

4.03e-04190343fe844559b95832845d2e8d3ab4b57e3d558bc372
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TMEM67 RP1 HYDIN

4.09e-04191343e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TMEM67 RP1 HYDIN

4.09e-041913439d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCellAdult-Immune-monocyte-D175|Adult / Lineage, Cell type, age group and donor

SULF2 PLEK NOD2

4.09e-04191343cbebb4d9550fdcd606cb3685ac9546c6b73fd422
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TMEM67 RP1 HYDIN

4.09e-041913431c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

TMEM67 RP1 HYDIN

4.15e-04192343be592e661367affced9ebe80849b466e6adb3a34
ToppCellIPF-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

TMEM67 RP1 HYDIN

4.15e-04192343d903bbd6c18e29e2c4cdedeb3fea1fd5ad7baa11
ToppCellFetal_29-31_weeks-Immune-monocyte-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SULF2 PLEK NOD2

4.15e-041923435417f024fcc89eaeab33f4a2c6421d1cfabd681b
ToppCellCOPD-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

TMEM67 RP1 HYDIN

4.15e-04192343eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCellIPF-Epithelial-Ciliated|IPF / Disease state, Lineage and Cell class

TMEM67 RP1 HYDIN

4.15e-04192343354adc1354bf596fbc60dd45c0169688e6f45165
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

TMEM67 RP1 HYDIN

4.22e-041933430b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCellLAM-Epithelial-AirwayEpi|Epithelial / Condition, Lineage and Cell class

TMEM67 RP1 HYDIN

4.22e-04193343f2672d2c495ee12c3b7d132452bde581fa5a7856
ToppCellControl-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

TMEM67 RP1 HYDIN

4.22e-041933430e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCell15-Trachea-Epithelial-Multiciliated_cell|Trachea / Age, Tissue, Lineage and Cell class

TMEM67 RP1 HYDIN

4.22e-04193343aa3acc7571405169efb656d214f3a8cbf988362e
Drugmiglustat

ENGASE GBA3 ABCA1 ASIC5 LCT

2.73e-0797335CID000051634
Drugemiglitate

ENGASE GBA3 LCT

4.19e-0622333CID000072004
DrugAC1L18MO

GBA3 LCT

1.22e-054332CID000000168
Drugthionitrobenzoate

LGSN SLC4A1 NOD2

1.47e-0533333CID000123648
DrugAC1MMKS7

ENGASE GBA3

2.03e-055332CID003262578
DrugU381

LCT NOD2

3.04e-056332CID002733286
Drugmaltulose

GBA3 LCT NOD2

3.78e-0545333CID000087177
Drug4-methylumbelliferone

ENGASE GBA3 SULF2 LCT

3.88e-05132334CID003364573
DrugDL-1,2-anhydro-myo-inositol

GBA3 ABCA1 LCT

4.04e-0546333CID000002859
DrugMerg

SLC4A1 NOD2

4.26e-057332CID000125299
Drugtrifoliin A

GBA3 SLC4A1

5.67e-058332CID005484006
Drugpyridoxine-5'-beta-D-glucoside

GBA3 LCT

5.67e-058332CID000440188
Drugbutylurea

GBA3 SLC4A1

5.67e-058332CID000011595
Drugconduritol B

GBA3 LCT

7.29e-059332CID000065317
DrugAC1LCY75

GBA3 LCT

9.10e-0510332CID000639298
DrugGlucuronides

UGT1A9 LCT

9.10e-0510332ctd:D020719
Drugmethyl beta-cellobioside

GBA3 LCT

1.11e-0411332CID000111276
DrugAC1L3VFE

GBA3 RP1 LCT

1.14e-0465333CID000122880
Drug3,6-anhydro-D-galactose 2-sulfate

LCT LGSN SLC4A1

1.14e-0465333CID000446806
Drugquercetin-4'-glucoside

GBA3 LCT

1.33e-0412332CID005320844
Drugtaxiphyllin

GBA3 SLC4A1

1.33e-0412332CID000107721
DrugNH4Cl

KCNK18 ENGASE LGSN SLC4A1

1.41e-04184334CID000025517
DrugAC1L9HHR

GBA3 EXOSC10 ABCA1 PLEK SLC4A1

1.47e-04354335CID000445141
Drugvaliolamine

GBA3 LCT

1.57e-0413332CID000174312
DrugMDL 25,637

GBA3 LCT

1.57e-0413332CID000128548
DrugN,N-diethyl-1-phenylcyclohexylamine

LCT SLC4A1

1.83e-0414332CID000604690
Drug2,5-xylidine

GBA3 LCT

2.11e-0415332CID000007259
DrugAC1OAGYH

GBA3 LCT

2.11e-0415332CID006857622
Drugquercetin-3,4'-diglucoside

GBA3 UGT1A9

2.41e-0416332CID005320835
Drugfagomine

GBA3 LCT

2.73e-0417332CID000072259
DrugNDPhA

SLC4A1 NOD2

2.73e-0417332CID000006838
Diseasehydrocephalus (implicated_via_orthology)

TMEM67 HYDIN

1.81e-0419312DOID:10908 (implicated_via_orthology)
Diseasecolorectal adenoma

DAB1 NOD2

5.53e-0433312EFO_0005406
DiseaseInflammatory Bowel Diseases

MUC19 NOD2

6.22e-0435312C0021390
Diseasenon-high density lipoprotein cholesterol measurement

DAB1 UGT1A9 ABCA1 RP1 HYDIN

8.20e-04713315EFO_0005689
Diseasekidney disease (implicated_via_orthology)

GBA3 LCT

8.54e-0441312DOID:557 (implicated_via_orthology)
Diseasecolitis (biomarker_via_orthology)

LCT NOD2

8.96e-0442312DOID:0060180 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
FEEAFFSFCETNGLE

SLC4A1

471

P02730
YCEEDYLFSGFQEAA

AJUBA

386

Q96IF1
AFGFGCEYFALFEEQ

ABCA1

786

O95477
GLFADSYSEKSQFCF

EEF1AKMT3

21

Q96AZ1
YAYDADFSCCSSFNG

CCM2L

366

Q9NUG4
LYCIAEGFDFFFSLS

ADAMTS16

681

Q8TE57
FLQFYFFFSLGTTEC

OR11H6

116

Q8NGC7
TQLDFENAFYFCFVT

KCNK18

306

Q7Z418
SYSFDGLCQYSFLED

MUC19

1291

Q7Z5P9
CDFGFDFDFLALDLT

MEX3D

451

Q86XN8
FALEDFCSSLFDGFF

NELFB

476

Q8WX92
VDAFLDYAAFCFSTF

LCT

516

P09848
LFDSYADFCFQTFGD

LCT

1041

P09848
YCFDADRFSSFEEAV

PTPRZ1

156

P23471
YDFNRYFCEDADFNL

GREB1L

1706

Q9C091
FYFFGSNATTECFLL

OR5AC1

101

P0C628
DFYRSFPGFQAFCET

EXOSC10

61

Q01780
FDFSFQDNSRYSEGF

HYDIN

4116

Q4G0P3
SNGYSFEDFEERFAA

DAB1

241

O75553
SFDKYAQFCFSTFGD

GBA3

141

Q9H227
DFAHVFTEYGNCFTF

ASIC5

196

Q9NY37
RVFFDSCDGFFTNYN

ENGASE

291

Q8NFI3
YNYIASFFIETGFCD

LGSN

296

Q5TDP6
FLQFYFFFSLGSTEC

OR11G2

136

Q8NGC1
YDCYFDNVGGEFSNT

PTGR1

211

Q14914
GDIFDQFYFSNTFDL

RP1

1986

P56715
DFATFDACGLFQFIF

TMEM67

261

Q5HYA8
LQYLSFGDFAFCAEL

FIBP

191

O43427
FYYFPDSGFFCEENS

PLEK

216

P08567
EQYCGDFDSFFSAKE

SH3BGR

136

P55822
FQCFFAAFYLALSAD

NOD2

606

Q9HC29
NGDRYCGDYDSFFES

SH3BGRL2

71

Q9UJC5
GSYNDIFDLFFSNCR

UGT1A9

111

O60656
ANDIYFASCAFGTED

ZMYND12

196

Q9H0C1
FCEFATGFLEYFDLN

SULF2

771

Q8IWU5