Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH2 DYNLT2 DNAH14 DNAH17 DNAH8	5.54e-06	37	139	5	GO:0045505
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH2 DNAH14 DNAH17 DNAH8	6.38e-06	18	139	4	GO:0008569
GeneOntologyMolecularFunction	microtubule motor activity	DNAH2 KIF4A DNAH14 DNAH17 KIF4B DNAH8	9.28e-06	70	139	6	GO:0003777
GeneOntologyMolecularFunction	RNA stem-loop binding	ERVK-6 DDX56 ERVK-7 ERVK-8	1.23e-05	21	139	4	GO:0035613
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH2 DNAH14 DNAH17 DNAH8	4.04e-05	28	139	4	GO:0051959
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-6 ERVK-7 ERVK-8	5.23e-05	11	139	3	GO:0004523
GeneOntologyMolecularFunction	RNA-directed DNA polymerase activity	ERVK-6 ERVK-7 ERVK-8	1.14e-04	14	139	3	GO:0003964
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-6 ERVK-7 ERVK-8 ERVK-19	1.24e-04	37	139	4	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-6 ERVK-7 ERVK-8 ERVK-19	1.38e-04	38	139	4	GO:0070001
GeneOntologyMolecularFunction	cytoskeletal motor activity	DNAH2 KIF4A DNAH14 DNAH17 KIF4B DNAH8	1.78e-04	118	139	6	GO:0003774
GeneOntologyMolecularFunction	nuclear estrogen receptor activity	PDE3A ESR1	2.86e-04	4	139	2	GO:0030284
GeneOntologyMolecularFunction	ATP-dependent activity	ABCA13 VPS4B DNAH2 KIF4A DDX56 XRCC5 DNAH14 TRAP1 MDN1 DNAH17 KIF4B DDX21 DNAH8	3.65e-04	614	139	13	GO:0140657
GeneOntologyMolecularFunction	cytoskeletal protein binding	NPHS1 DCDC2 SYNE1 SPTAN1 PPP1R9A KIF4A ACTN1 RMDN2 DCTN1 IQGAP1 ARL4C DST BRCA2 PLEKHM2 AVIL KIF4B DAAM1 FKBP4	6.28e-04	1099	139	18	GO:0008092
GeneOntologyCellularComponent	dynein complex	DNAH2 DYNLT2 DCTN1 DNAH14 DNAH17 DNAH8	1.61e-06	54	140	6	GO:0030286
GeneOntologyCellularComponent	microtubule	DCDC2 DNAH2 KIF4A DYNLT2 RMDN2 DCTN1 DNAH14 IQGAP1 RADIL DST DNAH17 ASPM KIF4B DNAH8 FKBP4	3.01e-06	533	140	15	GO:0005874
GeneOntologyCellularComponent	microtubule associated complex	DNAH2 KIF4A DYNLT2 DCTN1 DNAH14 DNAH17 KIF4B DNAH8	1.31e-05	161	140	8	GO:0005875
GeneOntologyCellularComponent	supramolecular fiber	DCDC2 SYNE1 SPTAN1 DNAH2 KIF4A DYNLT2 ACTN1 RMDN2 DCTN1 DNAH14 RYR3 IQGAP1 RADIL DST AVIL DNAH17 ASPM KIF4B DNAH8 DEK FKBP4	3.84e-05	1179	140	21	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	DCDC2 SYNE1 SPTAN1 DNAH2 KIF4A DYNLT2 ACTN1 RMDN2 DCTN1 DNAH14 RYR3 IQGAP1 RADIL DST AVIL DNAH17 ASPM KIF4B DNAH8 DEK FKBP4	4.23e-05	1187	140	21	GO:0099081
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	DCDC2 DNAH2 KIF4A DYNLT2 ACTN1 RMDN2 DCTN1 DNAH14 IQGAP1 RADIL DST AVIL DNAH17 ASPM KIF4B DNAH8 FKBP4	1.10e-04	899	140	17	GO:0099513
GeneOntologyCellularComponent	MSL complex	MSL1 MSL3	4.40e-04	5	140	2	GO:0072487
GeneOntologyCellularComponent	axonemal dynein complex	DNAH2 DNAH17 DNAH8	6.07e-04	25	140	3	GO:0005858
GeneOntologyCellularComponent	centrosome	DCDC2 AHI1 IFT57 VPS4B TOPBP1 CEP192 DCTN1 ITGB6 PPP4R3A CEP55 ODF2L BRCA2 GLE1 ASPM	6.73e-04	770	140	14	GO:0005813
GeneOntologyCellularComponent	midbody	SYNE1 VPS4B KIF4A IQGAP1 CEP55 ASPM KIF4B	7.55e-04	222	140	7	GO:0030496
GeneOntologyCellularComponent	cilium	ANO2 DCDC2 AHI1 IFT57 DNAH2 PPEF2 DCTN1 DNAH14 ODF2L GLE1 MROH2B DNAH17 VPS13A DAAM1 DNAH8	1.03e-03	898	140	15	GO:0005929
GeneOntologyCellularComponent	centriole	AHI1 CEP192 DCTN1 CEP55 ODF2L GLE1	1.08e-03	172	140	6	GO:0005814
GeneOntologyCellularComponent	B-WICH complex	DDX21 DEK	1.21e-03	8	140	2	GO:0110016
GeneOntologyCellularComponent	microtubule organizing center	DCDC2 AHI1 IFT57 VPS4B TOPBP1 CEP192 DCTN1 ITGB6 PPP4R3A CEP55 ODF2L BRCA2 GLE1 ASPM DAAM1	1.29e-03	919	140	15	GO:0005815
GeneOntologyCellularComponent	ATPase complex	RBBP7 VPS4B PBRM1 DDX21 DEK	1.78e-03	129	140	5	GO:1904949
GeneOntologyCellularComponent	nuclear pore cytoplasmic filaments	RANBP2 GLE1	1.93e-03	10	140	2	GO:0044614
GeneOntologyCellularComponent	ciliary basal body	AHI1 IFT57 DCTN1 ODF2L GLE1 DAAM1	2.04e-03	195	140	6	GO:0036064
GeneOntologyCellularComponent	microtubule end	DCTN1 DST ASPM	2.09e-03	38	140	3	GO:1990752
GeneOntologyCellularComponent	filtration diaphragm	NPHS1 IQGAP1	2.35e-03	11	140	2	GO:0036056
GeneOntologyCellularComponent	slit diaphragm	NPHS1 IQGAP1	2.35e-03	11	140	2	GO:0036057
Domain	ARM-type_fold	NBEAL1 SCYL3 RYR3 PPP4R3A AP4E1 PLAA UPF2 PIK3C2G MROH2B LTN1 ASPM DAAM1	6.12e-06	339	134	12	IPR016024
Domain	Spectrin	SYNE1 SPTAN1 ACTN1 DST	2.02e-05	23	134	4	PF00435
Domain	Spectrin_repeat	SYNE1 SPTAN1 ACTN1 DST	5.23e-05	29	134	4	IPR002017
Domain	SPEC	SYNE1 SPTAN1 ACTN1 DST	7.79e-05	32	134	4	SM00150
Domain	Spectrin/alpha-actinin	SYNE1 SPTAN1 ACTN1 DST	7.79e-05	32	134	4	IPR018159
Domain	CH	SYNE1 ACTN1 IQGAP1 DST ASPM	1.03e-04	65	134	5	SM00033
Domain	Dynein_heavy_chain_D4_dom	DNAH2 DNAH14 DNAH8	1.24e-04	14	134	3	IPR024317
Domain	Dynein_HC_stalk	DNAH2 DNAH14 DNAH8	1.24e-04	14	134	3	IPR024743
Domain	ATPase_dyneun-rel_AAA	DNAH2 MDN1 DNAH8	1.24e-04	14	134	3	IPR011704
Domain	MT	DNAH2 DNAH14 DNAH8	1.24e-04	14	134	3	PF12777
Domain	AAA_8	DNAH2 DNAH14 DNAH8	1.24e-04	14	134	3	PF12780
Domain	AAA_5	DNAH2 MDN1 DNAH8	1.24e-04	14	134	3	PF07728
Domain	SERPIN	SERPINA2 SERPINA4 SERPINI1 SERPINA10	1.39e-04	37	134	4	PS00284
Domain	SERPIN	SERPINA2 SERPINA4 SERPINI1 SERPINA10	1.39e-04	37	134	4	SM00093
Domain	CH	SYNE1 ACTN1 IQGAP1 DST ASPM	1.47e-04	70	134	5	PF00307
Domain	DHC_fam	DNAH2 DNAH14 DNAH8	1.54e-04	15	134	3	IPR026983
Domain	Dynein_heavy	DNAH2 DNAH14 DNAH8	1.54e-04	15	134	3	PF03028
Domain	Dynein_heavy_dom	DNAH2 DNAH14 DNAH8	1.54e-04	15	134	3	IPR004273
Domain	Serpin	SERPINA2 SERPINA4 SERPINI1 SERPINA10	1.55e-04	38	134	4	PF00079
Domain	-	SYNE1 ACTN1 IQGAP1 DST ASPM	1.57e-04	71	134	5	1.10.418.10
Domain	Serpin_fam	SERPINA2 SERPINA4 SERPINI1 SERPINA10	1.71e-04	39	134	4	IPR000215
Domain	CH	SYNE1 ACTN1 IQGAP1 DST ASPM	1.79e-04	73	134	5	PS50021
Domain	CH-domain	SYNE1 ACTN1 IQGAP1 DST ASPM	2.04e-04	75	134	5	IPR001715
Domain	ACTININ_2	SYNE1 ACTN1 DST	5.76e-04	23	134	3	PS00020
Domain	ACTININ_1	SYNE1 ACTN1 DST	5.76e-04	23	134	3	PS00019
Domain	Actinin_actin-bd_CS	SYNE1 ACTN1 DST	5.76e-04	23	134	3	IPR001589
Domain	-	STXBP4 SPTAN1 ACTN1 PPEF2 RYR3 RASGRP1 DST PLCB2	5.98e-04	261	134	8	1.10.238.10
Domain	ARM-like	SCYL3 PPP4R3A AP4E1 PLAA MROH2B LTN1 ASPM DAAM1	7.46e-04	270	134	8	IPR011989
Domain	EFhand_Ca_insen	SPTAN1 ACTN1	7.52e-04	6	134	2	PF08726
Domain	EF-hand_Ca_insen	SPTAN1 ACTN1	7.52e-04	6	134	2	IPR014837
Domain	EF-hand-dom_pair	STXBP4 SPTAN1 ACTN1 PPEF2 RYR3 RASGRP1 DST PLCB2	1.11e-03	287	134	8	IPR011992
Domain	DHC_N1	DNAH2 DNAH8	1.39e-03	8	134	2	PF08385
Domain	Dynein_heavy_dom-1	DNAH2 DNAH8	1.39e-03	8	134	2	IPR013594
Domain	-	COL6A6 XRCC5 ITGB6 MDN1	1.98e-03	74	134	4	3.40.50.410
Domain	Serpin_dom	SERPINA4 SERPINI1 SERPINA10	2.17e-03	36	134	3	IPR023796
Domain	Cyt_P450_E_grp-IV	CYP26B1 CYP7A1	2.21e-03	10	134	2	IPR002403
Domain	IQ	RASGRF2 PPEF2 IQGAP1 ASPM	2.75e-03	81	134	4	SM00015
Domain	P-loop_NTPase	SAMD9 ABCA13 VPS4B DNAH2 KIF4A DDX56 DNAH14 IQGAP1 ARL4C MDN1 ASPM KIF4B DDX21 DNAH8	3.12e-03	848	134	14	IPR027417
Domain	VWA	COL6A6 XRCC5 ITGB6 MDN1	3.14e-03	84	134	4	SM00327
Domain	AAA	ABCA13 VPS4B DNAH2 MDN1 DNAH8	3.83e-03	144	134	5	SM00382
Domain	AAA+_ATPase	ABCA13 VPS4B DNAH2 MDN1 DNAH8	3.83e-03	144	134	5	IPR003593
Domain	IQ_motif_EF-hand-BS	RASGRF2 PPEF2 IQGAP1 ASPM	4.02e-03	90	134	4	IPR000048
Domain	Dynein_heavy_dom-2	DNAH2 DNAH8	4.39e-03	14	134	2	IPR013602
Domain	DHC_N2	DNAH2 DNAH8	4.39e-03	14	134	2	PF08393
Domain	IQ	RASGRF2 PPEF2 IQGAP1 ASPM	4.52e-03	93	134	4	PS50096
Domain	EF-hand_1	SPTAN1 ACTN1 PPEF2 RYR3 DST	4.81e-03	152	134	5	PF00036
Domain	VWF_A	COL6A6 XRCC5 ITGB6 MDN1	5.64e-03	99	134	4	IPR002035
Domain	EFh	SPTAN1 ACTN1 PPEF2 RASGRP1 DST	5.66e-03	158	134	5	SM00054
Domain	EF_HAND_2	SPTAN1 ACTN1 PPEF2 RYR3 RASGRP1 DST	6.48e-03	231	134	6	PS50222
Domain	Cyt_P450_CS	CYP26B1 CYP7A1 CYP2U1	6.51e-03	53	134	3	IPR017972
Domain	SH3_1	AHI1 ARHGAP26 SPTAN1 DST ARHGEF9	6.61e-03	164	134	5	PF00018
Domain	EF_hand_dom	SPTAN1 ACTN1 PPEF2 RYR3 RASGRP1 DST	6.61e-03	232	134	6	IPR002048
Pathway	BIOCARTA_LIS1_PATHWAY	RELN DNAH2 DCTN1 DNAH8	9.21e-06	19	102	4	M22005
Pathway	REACTOME_NEPHRIN_FAMILY_INTERACTIONS	NPHS1 SPTAN1 ACTN1 IQGAP1	2.06e-05	23	102	4	M913
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT	DNAH2 DCTN1 DNAH17 DNAH8	3.99e-05	27	102	4	M47755
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	RANBP2 AKAP8 SYNE1 STXBP4 TOPBP1 KIF4A MSL1 CEP192 DCTN1 IQGAP1 CEP55 ODF2L RINT1 TRAP1 PBRM1 PLAA MSL3 ASPM KIF4B DDX21	4.29e-08	1155	140	20	20360068
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RANBP2 IFT57 STXBP4 SPTAN1 PPP1R9A SCYL3 CEP192 PPEF2 PPP4R3A CEP55 RINT1 PTPRB GSE1 MTMR14 LTN1 VPS13A CDC25A DEK FKBP4	4.80e-08	1049	140	19	27880917
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	RANBP2 SYNE1 SPTAN1 PPP1R9A DNAH2 SPG11 MSL1 ACTN1 XRCC5 DCTN1 IQGAP1 CHUK CCDC182 RINT1 TRAP1 DST MDN1 AVIL VPS13A ASPM DDX21 DNAH8	7.82e-08	1442	140	22	35575683
Pubmed	Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations.	RANBP2 AKAP8 SPTAN1 ACTN1 DCTN1 IQGAP1 TRAP1 PLAA DDX21	5.12e-07	235	140	9	28378594
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	AKAP8 SYNE1 STXBP4 SPTAN1 SPG11 CEP192 XRCC5 DCTN1 CEP55 RINT1 MDN1 MAP4K5 PANK4 VPS13A GKAP1 ASPM TMEM131L DAAM1 DDX21 DEK FKBP4	5.65e-07	1487	140	21	33957083
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-6 ERVK-7 ERVK-19	6.35e-07	5	140	3	12629516
Pubmed	Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.	DNAH2 DNAH17 DNAH8	2.21e-06	7	140	3	31178125
Pubmed	A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.	ABCA13 SPTAN1 KIF4A SLC3A1 RYR3 TRAP1 DST KIF4B TDRD6	2.45e-06	284	140	9	29459677
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	RANBP2 RBBP7 SPTAN1 KIF4A DDX56 ACTN1 XRCC5 IQGAP1 PBRM1 DST MDN1 DDX21 FKBP4	2.60e-06	653	140	13	22586326
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	RANBP2 AKAP8 SYNE1 PPP1R9A DDX56 ACTN1 XRCC5 IQGAP1 TRAP1 PBRM1 DST MDN1 GLE1 DDX21 DEK FKBP4	4.00e-06	1024	140	16	24711643
Pubmed	Identification of proteins associated with ligand-activated estrogen receptor α in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS.	AKAP8 RBBP7 ESR1 SPTAN1 DNAH2 ACTN1 DDX21 DEK	7.26e-06	245	140	8	21182205
Pubmed	The DNA sequence and analysis of human chromosome 6.	ERVK-6 FILIP1 DCDC2 AHI1 SYNE1 ESR1 DST MDN1 UPF2 TDRD6 DNAH8 DEK	8.79e-06	622	140	12	14574404
Pubmed	NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.	SYNE1 SPTAN1 ACTN1 INPP5F XRCC5 IQGAP1 PTPRB DDX21 CCDC180	8.86e-06	333	140	9	32665550
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	RANBP2 AKAP8 RBBP7 SYNE1 ESR1 PPP1R9A TOPBP1 KIF4A DDX56 MSL1 ACTN1 IQGAP1 CEP55 PBRM1 DST MDN1 ARHGEF9 LTN1 DAAM1	9.51e-06	1497	140	19	31527615
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	RANBP2 STXBP4 GPATCH1 ZNF507 CEP192 DCTN1 IQGAP1 CEP55 AP4E1 ODF2L RINT1 BRCA2 MTMR14 FKBP4	9.62e-06	853	140	14	28718761
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	AKAP8 TOPBP1 KIF4A DDX56 XRCC5 IQGAP1 PBRM1 MDN1 UPF2 GLE1 ASPM DDX21 DEK	1.30e-05	759	140	13	35915203
Pubmed	Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.	ERVK-6 ERVK-8 ERVK-19	1.37e-05	12	140	3	14557543
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	RANBP2 AKAP8 ARHGAP26 SPTAN1 IQGAP1 PBRM1 MDN1 DDX21	1.55e-05	272	140	8	31010829
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	FILIP1 RANBP2 AKAP8 RPS6KA5 SPTAN1 ZNF507 PPP4R3A IQGAP1 MDN1 GSE1 DBF4 MSL3 DDX21	1.60e-05	774	140	13	15302935
Pubmed	KIF4 regulates neuronal morphology and seizure susceptibility via the PARP1 signaling pathway.	KIF4A KIF4B	1.61e-05	2	140	2	36482480
Pubmed	The RNA-helicase DDX21 upregulates CEP55 expression and promotes neuroblastoma.	CEP55 DDX21	1.61e-05	2	140	2	33497018
Pubmed	The multiple functions of kinesin-4 family motor protein KIF4 and its clinical potential.	KIF4A KIF4B	1.61e-05	2	140	2	30081192
Pubmed	Chromokinesin Kif4 promotes proper anaphase in mouse oocyte meiosis.	KIF4A KIF4B	1.61e-05	2	140	2	31067151
Pubmed	ESR1/SYNE1 polymorphism and invasive epithelial ovarian cancer risk: an Ovarian Cancer Association Consortium study.	SYNE1 ESR1	1.61e-05	2	140	2	20056644
Pubmed	Cellular motor protein KIF-4 associates with retroviral Gag.	KIF4A KIF4B	1.61e-05	2	140	2	10559369
Pubmed	KIF4 regulates midzone length during cytokinesis.	KIF4A KIF4B	1.61e-05	2	140	2	21565503
Pubmed	A novel microtubule-based motor protein (KIF4) for organelle transports, whose expression is regulated developmentally.	KIF4A KIF4B	1.61e-05	2	140	2	7929562
Pubmed	Testing of variants of the MTHFR and ESR1 genes in 1798 Finnish individuals fails to confirm the association with migraine with aura.	ESR1 MTHFR	1.61e-05	2	140	2	17116097
Pubmed	Whole exome sequencing identifies novel variant underlying hereditary spastic paraplegia in consanguineous Pakistani families.	SPG11 CYP2U1	1.61e-05	2	140	2	31281085
Pubmed	High IKKα expression is associated with reduced time to recurrence and cancer specific survival in oestrogen receptor (ER)-positive breast cancer.	ESR1 CHUK	1.61e-05	2	140	2	28006839
Pubmed	IQGAP1 regulates actin cytoskeleton organization in podocytes through interaction with nephrin.	NPHS1 IQGAP1	1.61e-05	2	140	2	25652011
Pubmed	Whole genome expression microarray reveals novel roles for Kif4 in monocyte/macrophage cells.	KIF4A KIF4B	1.61e-05	2	140	2	31486502
Pubmed	Assignment of the kinesin family member 4 genes (KIF4A and KIF4B) to human chromosome bands Xq13.1 and 5q33.1 by in situ hybridization.	KIF4A KIF4B	1.61e-05	2	140	2	10773663
Pubmed	Missense Pathogenic variants in KIF4A Affect Dental Morphogenesis Resulting in X-linked Taurodontism, Microdontia and Dens-Invaginatus.	KIF4A KIF4B	1.61e-05	2	140	2	31616463
Pubmed	Kif4 regulates the expression of VEGFR1 through the PI3K/Akt signaling pathway in RAW264.7 monocytes/macrophages.	KIF4A KIF4B	1.61e-05	2	140	2	28350061
Pubmed	Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.	ERVK-6 ERVK-19	1.61e-05	2	140	2	9060628
Pubmed	The DEK oncogene is a target of steroid hormone receptor signaling in breast cancer.	ESR1 DEK	1.61e-05	2	140	2	23071688
Pubmed	IQGAP1 binds to estrogen receptor-α and modulates its function.	ESR1 IQGAP1	1.61e-05	2	140	2	24550401
Pubmed	Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.	ERVK-6 ERVK-19	1.61e-05	2	140	2	9460924
Pubmed	Myeloid Cell-Intrinsic IRF5 Promotes T Cell Responses through Multiple Distinct Checkpoints In Vivo, and IRF5 Immune-Mediated Disease Risk Variants Modulate These Myeloid Cell Functions.	ESR1 IRF5	1.61e-05	2	140	2	32690658
Pubmed	Kif4 interacts with EB1 and stabilizes microtubules downstream of Rho-mDia in migrating fibroblasts.	KIF4A KIF4B	1.61e-05	2	140	2	24658398
Pubmed	BRCA2 represses the transcriptional activity of pS2 by E2-ERα.	ESR1 BRCA2	1.61e-05	2	140	2	34952473
Pubmed	Phenotypic and functional consequences of haploinsufficiency of genes from exocyst and retinoic acid pathway due to a recurrent microdeletion of 2p13.2.	CYP26B1 EXOC6B	1.61e-05	2	140	2	23837398
Pubmed	Structural basis for the ATP-induced isomerization of kinesin.	KIF4A KIF4B	1.61e-05	2	140	2	23500491
Pubmed	Role of TRAP1 and estrogen receptor alpha in patients with ovarian cancer -a study of the OVCAD consortium.	ESR1 TRAP1	1.61e-05	2	140	2	22978347
Pubmed	A novel role of the chromokinesin Kif4A in DNA damage response.	KIF4A BRCA2	1.61e-05	2	140	2	18604178
Pubmed	Binding of murine leukemia virus Gag polyproteins to KIF4, a microtubule-based motor protein.	KIF4A KIF4B	1.61e-05	2	140	2	9658142
Pubmed	BPAG1n4 is essential for retrograde axonal transport in sensory neurons.	DCTN1 DST	1.61e-05	2	140	2	14581450
Pubmed	LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair.	RBBP7 XRCC5 IQGAP1 MDN1 DDX21	1.75e-05	79	140	5	26446488
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	RANBP2 AKAP8 RBBP7 GPATCH1 TOPBP1 KIF4A DDX56 MSL1 XRCC5 ZBTB14 PBRM1 DST MDN1 SLF2 MSL3 DDX21 DEK	1.89e-05	1294	140	17	30804502
Pubmed	SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.	RELN SYNE1 DCTN1	2.25e-05	14	140	3	19874786
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH2 DNAH17 DNAH8	2.25e-05	14	140	3	9373155
Pubmed	Gene expression in the developing mouse retina by EST sequencing and microarray analysis.	FILIP1 SPTAN1 RINT1 DST ASPM DEK	2.49e-05	142	140	6	11812828
Pubmed	The conserved Tpk1 regulates non-homologous end joining double-strand break repair by phosphorylation of Nej1, a homolog of the human XLF.	RANBP2 AKAP8 DDX56 XRCC5	2.50e-05	42	140	4	34244791
Pubmed	Update of the human and mouse SERPIN gene superfamily.	SERPINA2 SERPINA4 SERPINI1 SERPINA10	2.75e-05	43	140	4	24172014
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	RBBP7 STXBP4 ZNF507 TOPBP1 CEP192 PPP4R3A ODF2L GSE1 BRCA2 SLF2 ASPM	2.79e-05	588	140	11	38580884
Pubmed	A human MAP kinase interactome.	RANBP2 RPS6KA5 SYNE1 SPTAN1 ACTN1 DCTN1 PPP4R3A DST MAP4K5 ARHGEF9	2.94e-05	486	140	10	20936779
Pubmed	Scanning the human proteome for calmodulin-binding proteins.	RANBP2 DST SLF2 PAM DDX21	3.65e-05	92	140	5	15840729
Pubmed	Multiple mouse chromosomal loci for dynein-based motility.	DNAH2 DCTN1 DNAH14 DNAH8	3.92e-05	47	140	4	8812413
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	SPTAN1 DNAH2 TOPBP1 ACTN1 XRCC5 DCTN1 PPP4R3A PBRM1 MDN1 UPF2 COMMD10 DDX21 FKBP4	4.05e-05	847	140	13	35235311
Pubmed	Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.	RBBP7 TOPBP1 XRCC5 ZBTB14 BRCA2 DBF4	4.38e-05	157	140	6	30686591
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	RANBP2 AKAP8 COP1 KIF4A DCTN1 CHUK RINT1 MDN1 GSE1 PANK4 CDC25A DDX21 DEK	4.57e-05	857	140	13	25609649
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	PDE3A SYNE1 PBRM1 DST MDN1 ASPM DDX21	4.80e-05	234	140	7	36243803
Pubmed	Daam1 regulates fascin for actin assembly in mouse oocyte meiosis.	ACTN1 DAAM1	4.81e-05	3	140	2	28682694
Pubmed	Chromatoid Body Protein TDRD6 Supports Long 3' UTR Triggered Nonsense Mediated mRNA Decay.	UPF2 TDRD6	4.81e-05	3	140	2	27149095
Pubmed	Tumor formation via loss of a molecular motor protein.	KIF4A KIF4B	4.81e-05	3	140	2	16890532
Pubmed	KIF4 mediates anterograde translocation and positioning of ribosomal constituents to axons.	KIF4A KIF4B	4.81e-05	3	140	2	19158085
Pubmed	The HOX complex neighbored by the EVX gene, as well as two other homeobox-containing genes, the GBX-class and the EN-class, are located on the same chromosomes 2 and 7 in humans.	GBX1 GBX2	4.81e-05	3	140	2	7903253
Pubmed	Identification of the human homologue of mouse KIF4, a kinesin superfamily motor protein.	KIF4A KIF4B	4.81e-05	3	140	2	10978527
Pubmed	An αII Spectrin-Based Cytoskeleton Protects Large-Diameter Myelinated Axons from Degeneration.	SPTAN1 AVIL	4.81e-05	3	140	2	29038243
Pubmed	Comprehensive characterization of migration profiles of murine cerebral cortical neurons during development using FlashTag labeling.	RELN GBX2	4.81e-05	3	140	2	33851097
Pubmed	Epigenetic inactivation of the chromosomal stability control genes BRCA1, BRCA2, and XRCC5 in non-small cell lung cancer.	XRCC5 BRCA2	4.81e-05	3	140	2	17289874
Pubmed	Phosphorylation-dependent interactions of alpha-Actinin-1/IQGAP1 with the AMPA receptor subunit GluR4.	ACTN1 IQGAP1	4.81e-05	3	140	2	16190873
Pubmed	De novo mutations in MSL3 cause an X-linked syndrome marked by impaired histone H4 lysine 16 acetylation.	MSL1 MSL3	4.81e-05	3	140	2	30224647
Pubmed	Mutational analysis of the estrogen receptor-alpha gene in familial ovarian cancer.	ESR1 BRCA2	4.81e-05	3	140	2	16176503
Pubmed	Characterization of the interactions of the nephrin intracellular domain.	NPHS1 IQGAP1	4.81e-05	3	140	2	15634346
Pubmed	The role of retinoblastoma-associated proteins 46 and 48 in estrogen receptor alpha mediated gene expression.	RBBP7 ESR1	4.81e-05	3	140	2	18577416
Pubmed	FKBP52 and FKBP51 differentially regulate the stability of estrogen receptor in breast cancer.	ESR1 FKBP4	4.81e-05	3	140	2	35394865
Pubmed	Identification of pelvic organ prolapse risk susceptibility gene SNP locus in Xinjiang women.	ZFAT ESR1	4.81e-05	3	140	2	31270553
Pubmed	Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.	ERVK-6 ERVK-19	4.81e-05	3	140	2	10516026
Pubmed	Nuclear translocation of IGF-1R via p150(Glued) and an importin-β/RanBP2-dependent pathway in cancer cells.	RANBP2 DCTN1	4.81e-05	3	140	2	24909165
Pubmed	KIF4 motor regulates activity-dependent neuronal survival by suppressing PARP-1 enzymatic activity.	KIF4A KIF4B	4.81e-05	3	140	2	16630823
Pubmed	Nonsense in the testis: multiple roles for nonsense-mediated decay revealed in male reproduction.	UPF2 TDRD6	4.81e-05	3	140	2	28444146
Pubmed	CircKIF4A enhances osteosarcoma proliferation and metastasis by sponging MiR-515-5p and upregulating SLC7A11.	KIF4A KIF4B	4.81e-05	3	140	2	35579738
Pubmed	Oncotype Dx recurrence score among BRCA1/2 germline mutation carriers with hormone receptors positive breast cancer.	ESR1 BRCA2	4.81e-05	3	140	2	28120435
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	RANBP2 SPTAN1 ACTN1 XRCC5 DCTN1 PPP4R3A IQGAP1 TRAP1 MDN1 DDX21 FKBP4	5.82e-05	638	140	11	33239621
Pubmed	Characterization of the interaction of Aha1 with components of the Hsp90 chaperone machine and client proteins.	XRCC5 IQGAP1 FKBP4	6.92e-05	20	140	3	22504172
Pubmed	Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.	SYNE1 DST DNAH17	6.92e-05	20	140	3	21689717
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	RANBP2 AKAP8 RBBP7 SPTAN1 DDX56 COG3 XRCC5 IQGAP1 CHUK RINT1 TRAP1 DST MDN1 PANK4 LTN1 COMMD10 DEK	7.14e-05	1440	140	17	30833792
Pubmed	Sequence organization and matrix attachment regions of the human serine protease inhibitor gene cluster at 14q32.1.	SERPINA2 SERPINA4 SERPINA10	8.05e-05	21	140	3	15014966
Pubmed	TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.	RANBP2 ACTN1 XRCC5 IQGAP1 TRAP1 DDX21	9.06e-05	179	140	6	36261009
Pubmed	The role of Irf6 in tooth epithelial invagination.	IRF5 CHUK JAG2	9.30e-05	22	140	3	22366192
Pubmed	Sensory-motor circuit is a therapeutic target for dystonia musculorum mice, a model of hereditary sensory and autonomic neuropathy 6.	DST AVIL	9.60e-05	4	140	2	39058787
Pubmed	The Ah receptor recruits IKKα to its target binding motifs to phosphorylate serine-10 in histone H3 required for transcriptional activation.	RPS6KA5 CHUK	9.60e-05	4	140	2	24519526
Pubmed	Association of ESR1 (rs2234693 and rs9340799), CETP (rs708272), MTHFR (rs1801133 and rs2274976) and MS (rs185087) polymorphisms with Coronary Artery Disease (CAD).	ESR1 MTHFR	9.60e-05	4	140	2	32682401
Pubmed	Phenotypic analysis of familial breast cancer: comparison of BRCAx tumors with BRCA1-, BRCA2-carriers and non-familial breast cancer.	ESR1 BRCA2	9.60e-05	4	140	2	25736863
Pubmed	Disruption of the MSL complex inhibits tumour maintenance by exacerbating chromosomal instability.	MSL1 MSL3	9.60e-05	4	140	2	33837287
Pubmed	Kinesin KIF4 regulates intracellular trafficking and stability of the human immunodeficiency virus type 1 Gag polyprotein.	KIF4A KIF4B	9.60e-05	4	140	2	18684836
Pubmed	Kif4 Is Essential for Mouse Oocyte Meiosis.	KIF4A KIF4B	9.60e-05	4	140	2	28125646
Pubmed	Maternal IVS1-401 T allele of the estrogen receptor alpha is an independent predictor of late fetal loss.	ESR1 MTHFR	9.60e-05	4	140	2	16753154
Interaction	PRC1 interactions	RANBP2 AKAP8 RBBP7 SYNE1 SPTAN1 PPP1R9A KIF4A DDX56 SPG11 ACTN1 XRCC5 DCTN1 IQGAP1 TRAP1 PBRM1 KIF4B CDC25A DDX21 DEK SPRYD4	8.47e-06	973	136	20	int:PRC1
Interaction	NINL interactions	AHI1 RBBP7 STXBP4 GPATCH1 CEP192 XRCC5 DCTN1 IQGAP1 CEP55 ODF2L GSE1 BRCA2 YJU2B	1.39e-05	458	136	13	int:NINL
Cytoband	14q32.13	SERPINA2 SERPINA4 SERPINA10	1.79e-05	17	139	3	14q32.13
Cytoband	19q13.11	DPY19L3 GPATCH1 ZNF507	3.51e-04	45	139	3	19q13.11
Cytoband	2p13.2	CYP26B1 EXOC6B	5.89e-04	12	139	2	2p13.2
Cytoband	12p12	PDE3A PIK3C2G	6.95e-04	13	139	2	12p12
GeneFamily	Dyneins, axonemal	DNAH2 DNAH14 DNAH17 DNAH8	1.48e-06	17	93	4	536
GeneFamily	Serpin peptidase inhibitors	SERPINA2 SERPINA4 SERPINI1 SERPINA10	3.80e-05	37	93	4	739
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	RANBP2 TOPBP1 SPG11 INPP5F DST MDN1 GSE1 UPF2 BRCA2 DBF4 MAP4K5 LTN1 VPS13A TMEM131L DAAM1 DDX21 DEK	2.05e-06	856	135	17	M4500
Coexpression	LAZARO_GENETIC_MOUSE_MODEL_HIGH_GRADE_LARGE_CELL_NEUROENDOCRINE_LUNG_CARCINOMA_UP	RBBP7 ESR1 TOPBP1 KIF4A CEP55 ODF2L BRCA2 DBF4 ASPM KIF4B CDC25A	7.88e-06	402	135	11	MM454
Coexpression	ERBB2_UP.V1_DN	CYP26B1 IFT57 TOPBP1 INPP5F RASGRP1 DBF4 LTN1 HERC6	8.66e-06	197	135	8	M2635
Coexpression	LAKE_ADULT_KIDNEY_C14_DISTAL_CONVOLUTED_TUBULE	TRPM6 DCDC2 AHI1 DNAH14 DST PIK3C2G EXOC6B COMMD10	1.29e-05	208	135	8	M39233
Coexpression	LAKE_ADULT_KIDNEY_C24_ENDOTHELIAL_CELLS_AEA_AND_DVR	PDE3A SYNE1 ARHGAP26 IQGAP1 PTPRB DST EXOC6B	1.43e-05	152	135	7	M39243
Coexpression	GSE37605_C57BL6_VS_NOD_FOXP3_IRES_GFP_TCONV_DN	FILIP1 CYP26B1 IFT57 SCYL3 IRF5 RINT1 SERPINI1	2.16e-05	162	135	7	M8827
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	OMA1 AHI1 SPG11 CEP192 CEP55 RINT1 PBRM1 DBF4 GKAP1 ASPM DAAM1 DDX21 DEK	3.60e-05	656	135	13	M18979
Coexpression	YAMASHITA_LIVER_CANCER_STEM_CELL_DN	CYP7A1 ESR1 APOC4 PIK3C2G C6	4.64e-05	76	135	5	M9206
Coexpression	GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_DN	AHI1 DDX56 ZC3H6 RGS10 ODF2L MDN1 DAAM1	7.98e-05	199	135	7	M6028
Coexpression	GSE28237_FOLLICULAR_VS_EARLY_GC_BCELL_DN	RELN DYNLT2 RGS10 CEP55 ASPM DDX21 DEK	8.23e-05	200	135	7	M4885
Coexpression	GSE43863_TH1_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_DN	RASGRF2 SPTAN1 MSL1 RGS10 JAG2 SERPINI1 EXOC6B	8.23e-05	200	135	7	M9765
Coexpression	GSE21670_TGFB_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_DN	RASGRF2 NBEAL1 ARHGAP26 ACTN1 RASGRP1 SERPINI1 DNAH8	8.23e-05	200	135	7	M7432
Coexpression	GSE5589_UNSTIM_VS_180MIN_LPS_STIM_MACROPHAGE_DN	TOPBP1 RGS10 BRCA2 MTMR14 ASPM TMEM131L DEK	8.23e-05	200	135	7	M6601
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 DCDC2 ARHGAP26 ACTN1 ITGB6 DST MTHFR PAM	1.01e-07	184	136	8	d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCell	COVID_vent-Lymphocytic-Proliferative_Lymphocyte-\|COVID_vent / Disease condition, Lineage, Cell class and subclass	RBBP7 TOPBP1 KIF4A CEP55 BRCA2 ASPM CDC25A DEK	1.92e-07	200	136	8	7e4c0db43a03ca11380a54f44a3cf1991e055b80
ToppCell	COVID_vent-Lymphocytic-Proliferative_Lymphocyte\|COVID_vent / Disease condition, Lineage, Cell class and subclass	RBBP7 TOPBP1 KIF4A CEP55 BRCA2 ASPM CDC25A DEK	1.92e-07	200	136	8	9775ca7dedb76fcbb74f80f86b33c94e394c320a
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D122\|Adult / Lineage, Cell type, age group and donor	ANO2 PDE3A CYP26B1 RASGRF2 RYR3 JAG2 PTPRB	8.70e-07	168	136	7	8c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FILIP1 CYP26B1 ZNF507 ODF2L RINT1 PTPRB DNAH8	1.33e-06	179	136	7	025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIF4A APOC4 CHRNA5 CEP55 BRCA2 ASPM DEK	1.43e-06	181	136	7	73b1b59810f60e3e39ca1d5073a5a0d4f5377e6e
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FILIP1 RELN COL6A6 IQGAP1 RAD51AP2 DST VPS13A	2.35e-06	195	136	7	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FILIP1 RELN COL6A6 IQGAP1 RAD51AP2 DST VPS13A	2.35e-06	195	136	7	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF4A CEP55 ARL4C PTPRB DBF4 ASPM DEK	2.43e-06	196	136	7	20383d576708b7e4bfce3e9fe40548cce496e3cb
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF4A CEP55 ARL4C PTPRB DBF4 ASPM DEK	2.43e-06	196	136	7	0644bd14a944b9c9759a295dfdd5e67a4775f20a
ToppCell	Sepsis-Leuk-UTI-Lymphocyte-T/NK-MAIT\|Leuk-UTI / Disease, condition lineage and cell class	NBEAL1 SYNE1 PPP1R9A DDX56 CHRNA5 ARL4C ODF2L	2.78e-06	200	136	7	7e0d0f051c197c2c70080f039e1c4dd68db8e74f
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	OMA1 DPY19L3 ZNF507 RGS10 MTHFR PLCB2	1.06e-05	162	136	6	810881210e015c788814e4fe8d7a24c929cf2621
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	SYNE1 KIF4A CEP55 JAG2 ARL4C ASPM	1.26e-05	167	136	6	abc4ba308ca3be41b0da604f5d82579fd58dff7b
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF4A CEP55 ODF2L DBF4 ASPM DAAM1	1.59e-05	174	136	6	1779e67382cb2644534ffb5b9b8f28d32935f4ea
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FILIP1 RANBP2 NBEAL1 SYNE1 PTPRB HERC6	1.81e-05	178	136	6	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF4A CEP55 ARL4C DBF4 ASPM DEK	1.87e-05	179	136	6	54191c00b29f53b520cd3243b5791daa4a2c72d7
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF4A CEP55 ARL4C DBF4 ASPM DEK	1.93e-05	180	136	6	5e1680088065be14447d5d5465f91f7edd071a1e
ToppCell	3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_Myeloid\|bone_marrow / Manually curated celltypes from each tissue	KIF4A ACTN1 CEP55 BRCA2 ASPM CDC25A	2.05e-05	182	136	6	6745d464c3ff289726aa8164e9a43f407f8e4380
ToppCell	10x5'-Liver-Lymphocytic_T_CD4/8-lo-Cycling_T\|Liver / Manually curated celltypes from each tissue	KIF4A CEP55 BRCA2 ASPM KIF4B DEK	2.05e-05	182	136	6	81557cdc88777f3bd4e1dd18a760b08fc29122ef
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5\|TCGA-Liver / Sample_Type by Project: Shred V9	TMIGD1 KIF4A CEP55 BRCA2 DBF4 ASPM	2.12e-05	183	136	6	f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCell	CV-Severe-3\|CV / Virus stimulation, Condition and Cluster	ACTN1 IQGAP1 BRCA2 ASPM CDC25A DEK	2.18e-05	184	136	6	1c9bda00bb6efd98f68781ca06655bf6c4282f27
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANO2 RELN ABCA13 CYP7A1 RYR3 PIK3C2G	2.18e-05	184	136	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANO2 RELN ABCA13 CYP7A1 RYR3 PIK3C2G	2.18e-05	184	136	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANO2 RELN ABCA13 CYP7A1 RYR3 PIK3C2G	2.18e-05	184	136	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	COVID-19_Severe-gd_T\|COVID-19_Severe / Disease condition and Cell class	SYNE1 ARHGAP26 PPP4R3A IQGAP1 ARL4C GSE1	2.18e-05	184	136	6	791f1bcb954aadc63d4117c400537d036f68734d
ToppCell	Adult-Endothelial-endothelial_cell_of_artery\|Adult / Lineage, Cell type, age group and donor	ANO2 PDE3A CYP26B1 RASGRF2 RYR3 PTPRB	2.32e-05	186	136	6	2d1c4ea2e401db89971582ee54618a8b0c81b8ac
ToppCell	Severe-B_intermediate-1\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	PPP4R3A CCDC182 PIK3C2G TMEM131L C6	2.32e-05	111	136	5	7021009545178fac1f19f3c429bfedb2f38b680d
ToppCell	PCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ANO2 RASGRF2 GBX2 DENND3 JAG2 PTPRB	2.39e-05	187	136	6	29b2e2be26a9d72b154760e47acf61cfe2f45fa7
ToppCell	CV-Severe-3\|Severe / Virus stimulation, Condition and Cluster	IQGAP1 BRCA2 ASPM DAAM1 CDC25A DEK	2.39e-05	187	136	6	68cb43a73945f5e252530da25613f6b3f484b4d5
ToppCell	droplet-Marrow-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 SYNE1 TOPBP1 PLCB2 CDC25A DNAH8	2.39e-05	187	136	6	14c239af77116d28d511dea754b6150d20488080
ToppCell	10x5'-Liver-Lymphocytic_NK-Cycling_NK\|Liver / Manually curated celltypes from each tissue	KIF4A CEP55 BRCA2 ASPM CDC25A DEK	2.46e-05	188	136	6	5eb94e652a734c6f15c68a178e9d05f0febcf34c
ToppCell	Multiple_Sclerosis-Lymphocyte-T_NK-T_NK_proliferative\|Multiple_Sclerosis / Disease, Lineage and Cell Type	KIF4A CEP55 BRCA2 ASPM KIF4B CDC25A	2.46e-05	188	136	6	6c05797a5d0635d89ffcf4aca52178687129ccb4
ToppCell	Endothelial-endothelial_cell_of_artery\|World / Lineage, Cell type, age group and donor	ANO2 PDE3A CYP26B1 RASGRF2 JAG2 PTPRB	2.54e-05	189	136	6	fdd89c71113ac99b7c800c6def8888e512ff1128
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ANO2 PDE3A C12orf56 RASGRF2 JAG2 PTPRB	2.54e-05	189	136	6	12b6f1c3bf526b90e112374bf937701f645c5780
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 DCDC2 ACTN1 ITGB6 DST PIK3C2G	2.54e-05	189	136	6	e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCell	Control-Endothelial-Endothelial-FOXM1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF4A CEP55 BRCA2 DBF4 ASPM CDC25A	2.54e-05	189	136	6	1e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	FILIP1 PDE3A GBX1 DST EXOC6B PAM	2.69e-05	191	136	6	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANO2 C12orf56 RASGRF2 RYR3 JAG2 PTPRB	2.69e-05	191	136	6	b2c86cde341fe350143658c8a8a4a9edbce3f19b
ToppCell	Endothelial-D_(cycle)\|World / shred on cell class and cell subclass (v4)	KIF4A CEP55 PTPRB DBF4 ASPM DEK	2.69e-05	191	136	6	49a4d8f181558e3be9527a8ff9a178f3bb01323c
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	RANBP2 AHI1 IFT57 PPP4R3A DBF4 DDX21	2.69e-05	191	136	6	1ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	FILIP1 IFT57 NBEAL1 PPP1R9A ITGB6 DNAH14	2.69e-05	191	136	6	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SYNE1 SPTAN1 ARL4C RASGRP1 ODF2L VPS13A	2.69e-05	191	136	6	4a29b7d5cd10e9077699d3aa76e3db6c4d5a0cf6
ToppCell	PCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DCDC2 KCNH8 PPP1R9A KIF4A CEP55 ASPM	2.77e-05	192	136	6	25378b5e4b0cea8415ff125783511fc25a56fc00
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ANO2 RASGRF2 ARHGAP26 RYR3 PTPRB GSE1	2.77e-05	192	136	6	c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANO2 PDE3A C12orf56 RYR3 JAG2 PTPRB	2.85e-05	193	136	6	0b328f725f6feba263783eaca60c142e80df90f3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ANO2 RASGRF2 ARHGAP26 RYR3 PTPRB GSE1	2.85e-05	193	136	6	52e918884877b6659cdca0496390e440f73694a9
ToppCell	nucseq-Epithelial-Epithelial_Alveolar\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FILIP1 SYNE1 PPP1R9A ITGB6 DNAH14 PAM	2.94e-05	194	136	6	53f3e49e91b1096f3226010e2de767efb490dfe4
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 PDE3A ESR1 ACTN1 DST DAAM1	2.94e-05	194	136	6	90efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 PDE3A ESR1 ACTN1 DST DAAM1	2.94e-05	194	136	6	df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF4A CEP55 PTPRB DBF4 ASPM DEK	2.94e-05	194	136	6	3a49c7c86036e09a8cd0114988380d04ad1a26fb
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating\|367C / Donor, Lineage, Cell class and subclass (all cells)	KIF4A CEP55 BRCA2 ASPM KIF4B CDC25A	2.94e-05	194	136	6	a12b64945e10f00aa983678a02586c59badc1570
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF4A RGS10 CEP55 BRCA2 ASPM DEK	3.02e-05	195	136	6	db1660ce74819cd816bdcfcae5efb3aad82cce66
ToppCell	nucseq-Epithelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FILIP1 IFT57 SYNE1 PPP1R9A ITGB6 DNAH14	3.02e-05	195	136	6	9406866f99555198a9be311fbd65751b70f35446
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	AHI1 IFT57 ZNF507 RASGRP1 ODF2L DBF4	3.02e-05	195	136	6	ed5f772c82d4dfd1c8735224446ec9feae3fb8c2
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	KIF4A CEP55 BRCA2 ASPM KIF4B CDC25A	3.11e-05	196	136	6	9591a6a3477ed6a1e2e016f7542e38603d8b16cb
ToppCell	background-Endothelial_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	FILIP1 RELN ARHGAP26 ODF2L PTPRB PAM	3.11e-05	196	136	6	e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCell	ICU-SEP-Lymphocyte-T_NK-T_NK_proliferative\|ICU-SEP / Disease, Lineage and Cell Type	KIF4A CEP55 BRCA2 DBF4 ASPM CDC25A	3.20e-05	197	136	6	908e91fa16134b61943aea5e8fc0d6fbac8a8c6e
ToppCell	ILEUM-non-inflamed-(5)_Plasma-(5)_Plasmablasts\|(5)_Plasma / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	XRCC5 CEP55 ARL4C ASPM DDX21 DEK	3.20e-05	197	136	6	ffc55028052311ed8d173a2db1a9f664391fe8d8
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF4A CEP55 PTPRB DBF4 ASPM DEK	3.20e-05	197	136	6	a41420d4b6d502c2f594c054c7efbb5d4eac83ff
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF4A CEP55 PTPRB DBF4 ASPM DEK	3.20e-05	197	136	6	1c89d6836eed30c50c765f7dde9cc8ee15c363d2
ToppCell	LPS_only-Endothelial-Endothelial-FOXM1\|LPS_only / Treatment groups by lineage, cell group, cell type	ZNF507 KIF4A DYNLT2 CEP55 BRCA2 ASPM	3.20e-05	197	136	6	038fd92750257d43d5e980fd06d77742b543f11a
ToppCell	distal-1-Hematologic-Proliferating_Macrophage\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KIF4A CEP55 BRCA2 ASPM KIF4B CDC25A	3.29e-05	198	136	6	df3f5559ecd1f3cd1fd60e39dbad8741309e83a3
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SYNE1 KIF4A CEP55 ARL4C RASGRP1 ASPM	3.29e-05	198	136	6	80b105a7c7d00ea3b5e586831fbb755bd84f9d1a
ToppCell	distal-Hematologic-Proliferating_Macrophage-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KIF4A CHRNA5 CEP55 BRCA2 ASPM CDC25A	3.29e-05	198	136	6	2b0716e900bce54ad1825d6dcdaf4ebf31f355c4
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYNE1 KIF4A CEP55 ARL4C RASGRP1 ASPM	3.29e-05	198	136	6	c73e906d2d12d6eba0e606958be16e63a2292cd0
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	TOPBP1 KIF4A CEP55 ARL4C BRCA2 ASPM	3.39e-05	199	136	6	305a9ade5bbe8e981e7c641c9a5e0c9f8ef60470
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	SYNE1 KIF4A CEP55 BRCA2 ASPM CDC25A	3.39e-05	199	136	6	101f78fe6dd1bf9e2e4dd5ad8a970312b3540927
ToppCell	Healthy_Control-Lymphoid-T\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	SYNE1 KIF4A CEP55 ARL4C RASGRP1 ASPM	3.39e-05	199	136	6	f22438fc9c02d0a4d7c936f9420b913aca851ea1
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYNE1 KIF4A CEP55 BRCA2 ASPM CDC25A	3.39e-05	199	136	6	e0fcec796afe75e42467ca86355b9fc5aa9ae0a1
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TOPBP1 KIF4A CEP55 ARL4C BRCA2 ASPM	3.39e-05	199	136	6	fba48342066aab41a8bcb20db40a6df0158e1cbe
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Proliferating-Cycling_IN_Progenitors\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	KIF4A CEP55 BRCA2 DBF4 ASPM DEK	3.39e-05	199	136	6	f315ec3fb6c0799668c9195f836a77fc0db2b615
ToppCell	TCGA-Stomach-Primary_Tumor\|TCGA-Stomach / Sample_Type by Project: Shred V9	TOPBP1 KIF4A CEP55 DBF4 ASPM DDX21	3.39e-05	199	136	6	38f1f612b29feb868322999ceeda78e52447ec4f
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma\|TCGA-Stomach / Sample_Type by Project: Shred V9	TOPBP1 KIF4A CEP55 DBF4 ASPM DDX21	3.39e-05	199	136	6	b10698aee2e6c17bc559eb4f723024141f914b90
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon-Neuronal-Ventral_Precursors\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	KIF4A CEP55 BRCA2 DBF4 ASPM DEK	3.48e-05	200	136	6	c8ea0db79b1521f8c90d0d749280c354d3907c3a
ToppCell	Hematolymphoid-Endothelial-NOSTRIN\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	ANO2 RASGRF2 SYNE1 ACTN1 IQGAP1 PAM	3.48e-05	200	136	6	032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells-Neuroepithelial_cell\|2m / Sample Type, Dataset, Time_group, and Cell type.	KIF4A CEP55 BRCA2 DBF4 ASPM DEK	3.48e-05	200	136	6	0d9b8d51a7630e70e60c76c763ff82df4c559152
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon-Proliferating-Cycling_Progenitors_nGenesUnder4k\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	KIF4A CEP55 BRCA2 DBF4 ASPM DEK	3.48e-05	200	136	6	8223d2c9b9e05b1d26e3de1bc0226d175af2e7b2
ToppCell	healthy_donor-Lymphocytic-Proliferative_Lymphocyte\|healthy_donor / Disease condition, Lineage, Cell class and subclass	KIF4A CEP55 BRCA2 ASPM KIF4B CDC25A	3.48e-05	200	136	6	e4eb915c29909cf8535a3603c68976545c05e54b
ToppCell	Hematolymphoid-Endothelial-NOSTRIN---\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	ANO2 RASGRF2 SYNE1 ACTN1 IQGAP1 PAM	3.48e-05	200	136	6	68fce28690246895fd33354b30960ebcc31aa4cc
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells\|2m / Sample Type, Dataset, Time_group, and Cell type.	KIF4A CEP55 BRCA2 DBF4 ASPM DEK	3.48e-05	200	136	6	0675f580ccef705875854247bbfd4ee2bcf126a1
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon-Proliferating-Cycling\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	KIF4A CEP55 BRCA2 DBF4 ASPM DEK	3.48e-05	200	136	6	322337a5a9cc2de1913ee9258c98ae51fb4bd6bb
ToppCell	metastatic_Lymph_Node-T/NK_cells-Undetermined\|T/NK_cells / Location, Cell class and cell subclass	KIF4A CEP55 BRCA2 ASPM CDC25A DEK	3.48e-05	200	136	6	9c2095dcf70f1288d55d0ff4a97efd4fd8d0c9ee
ToppCell	Hematolymphoid-Endothelial-NOSTRIN-\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	ANO2 RASGRF2 SYNE1 ACTN1 IQGAP1 PAM	3.48e-05	200	136	6	376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCell	Control_saline-Endothelial-Endothelial-Artery\|Control_saline / Treatment groups by lineage, cell group, cell type	PDE3A CYP26B1 RPS6KA5 JAG2 PTPRB DST	3.48e-05	200	136	6	65b71f1e8da5c3750fcd0a2e66d9ef3125a3f78a
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-CD4+_T_activated\|COVID-19_Mild / Disease, condition lineage and cell class	SAMD9 RASGRF2 SPTAN1 DST MDN1 HERC6	3.48e-05	200	136	6	d9e8a0d047d4403fb7265fde7448e23a7780785c
ToppCell	healthy_donor-Lymphocytic-Proliferative_Lymphocyte-\|healthy_donor / Disease condition, Lineage, Cell class and subclass	KIF4A CEP55 BRCA2 ASPM KIF4B CDC25A	3.48e-05	200	136	6	415e7556b5ac45688e2c6c30a52bd40e0eb27c7d
ToppCell	Non-neuronal-Dividing-IPC\|World / Primary Cells by Cluster	KIF4A CEP55 BRCA2 DBF4 ASPM DEK	3.48e-05	200	136	6	971533181daa1bfac1f1b8c507d2013f891f9078
ToppCell	Hematolymphoid-Endothelial-NOSTRIN--\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	ANO2 RASGRF2 SYNE1 ACTN1 IQGAP1 PAM	3.48e-05	200	136	6	7fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCell	Non-neuronal-Dividing-Radial_Glia-vRG-17\|World / Primary Cells by Cluster	KIF4A CEP55 BRCA2 DBF4 ASPM DEK	3.48e-05	200	136	6	4417f14d45ce683c1a45ec989ae63ee6c047353e
ToppCell	Sepsis-ICU-SEP-Lymphocyte-T/NK-T/NK_proliferative\|ICU-SEP / Disease, condition lineage and cell class	KIF4A CEP55 BRCA2 DBF4 ASPM CDC25A	3.48e-05	200	136	6	ae500c8b7c2162cadd31bf44ee9dc3271192cf17
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon-Proliferating\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	KIF4A CEP55 BRCA2 DBF4 ASPM DEK	3.48e-05	200	136	6	c784459a62bebec560e79aba83de8611457437bc
ToppCell	distal-3-Hematologic-Proliferating_Macrophage\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KIF4A CHRNA5 CEP55 BRCA2 ASPM CDC25A	3.48e-05	200	136	6	1b65c97e8123d0572d31525d6a10bc7f16857959
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Proliferating\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	KIF4A CEP55 BRCA2 DBF4 ASPM DEK	3.48e-05	200	136	6	2154c976f96489d0fa7bfe6ac1cd21edcbefe735
ToppCell	LPS_only-Endothelial-Endothelial-Artery\|LPS_only / Treatment groups by lineage, cell group, cell type	CYP26B1 SPTAN1 JAG2 PTPRB DST DAAM1	3.48e-05	200	136	6	b17eb1587ca86c3d40515128a00a8d8fd787fccf
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Artery\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PDE3A CYP26B1 JAG2 PTPRB DST DAAM1	3.48e-05	200	136	6	b1ff8d61b567f85006d6d20093f9c803b6d34674
ToppCell	Hematolymphoid-Endothelial-NOSTRIN----L2-6\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	ANO2 RASGRF2 SYNE1 ACTN1 IQGAP1 PAM	3.48e-05	200	136	6	878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCell	Hematolymphoid-Endothelial\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	ANO2 RASGRF2 SYNE1 ACTN1 IQGAP1 PAM	3.48e-05	200	136	6	7136936d05ab344a560cf159684c881063b5430d
ToppCell	Sepsis-Leuk-UTI-Lymphocyte-T/NK-T/NK_proliferative\|Leuk-UTI / Disease, condition lineage and cell class	KIF4A CEP55 BRCA2 DBF4 ASPM CDC25A	3.48e-05	200	136	6	093e97395be23092229521cc55aaaee8befbc149
ToppCell	mild-T/NK_proliferative\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TOPBP1 KIF4A CEP55 BRCA2 ASPM CDC25A	3.48e-05	200	136	6	63cc57b9331459efbb73051d174d198a3568b938
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon-Proliferating\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	KIF4A CEP55 BRCA2 DBF4 ASPM DEK	3.48e-05	200	136	6	8f9e76048ae6f45218a09a95a2c4b31e8a8937b2
Computational	Neighborhood of IL16	RPS6KA5 ESR1 ZBTB14 RYR3 SERPINA4 PTPRB GLE1 MSL3	2.48e-04	239	75	8	MORF_IL16
Computational	Neighborhood of BCL2L11	RPS6KA5 ZBTB14 RYR3 SERPINA4 PTPRB GLE1 MSL3	3.05e-04	186	75	7	MORF_BCL2L11
Computational	Neighborhood of SUPT3H	RPS6KA5 RBBP7 ZBTB14 RYR3 SERPINA4 PTPRB GLE1 MSL3 C6	4.38e-04	328	75	9	MORF_SUPT3H
Computational	Neighborhood of ATF2	RPS6KA5 RBBP7 ZBTB14 RYR3 SERPINA4 PTPRB GLE1 MSL3 C6	4.58e-04	330	75	9	MORF_ATF2
Computational	Neighborhood of MAGEA9	RPS6KA5 RBBP7 ESR1 ZBTB14 RYR3 SERPINA4 PTPRB GLE1 MSL3 C6	6.72e-04	423	75	10	MORF_MAGEA9
Computational	Neighborhood of MDM2	RPS6KA5 RBBP7 ZBTB14 RYR3 SERPINA4 PTPRB GLE1 MSL3	6.97e-04	279	75	8	MORF_MDM2
Computational	Neighborhood of FSHR	RPS6KA5 RBBP7 ZBTB14 RYR3 SERPINA4 PTPRB EXOC6B C6	6.97e-04	279	75	8	MORF_FSHR
Disease	threonine measurement	MAP4K5 MROH2B C6 SPRYD4	2.46e-05	37	135	4	EFO_0009775
Disease	level of prefoldin subunit 3 in blood serum	MROH2B C6	6.21e-05	3	135	2	OBA_2044087
Disease	susceptibility to rheumatic fever measurement	RELN RYR3 CDC25A	2.82e-04	28	135	3	EFO_0008416
Disease	cholesteryl ester measurement, low density lipoprotein cholesterol measurement	CYP7A1 DDX56 APOC4 BRCA2 MAP4K5	2.92e-04	126	135	5	EFO_0004611, EFO_0010351
Disease	thrombophilia (is_implicated_in)	MTHFR SERPINA10	3.08e-04	6	135	2	DOID:2452 (is_implicated_in)
Disease	Bipolar Disorder	RELN ABCA13 SYNE1 ESR1 RASGRP1 PBRM1 BRCA2 MTHFR DNAH8	3.62e-04	477	135	9	C0005586
Disease	Malignant neoplasm of breast	AKAP8 RASGRF2 SYNE1 ESR1 STXBP4 SPTAN1 APOC4 COG3 EPG5 JAG2 PBRM1 BRCA2 MTHFR DEK	4.21e-04	1074	135	14	C0006142
Disease	infertility (implicated_via_orthology)	ESR1 BRCA2	4.30e-04	7	135	2	DOID:5223 (implicated_via_orthology)
Disease	triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	PDE3A DDX56 SPG11 APOC4 CEP55 MAP4K5	6.10e-04	225	135	6	EFO_0008317, EFO_0020947
Disease	DCN1-like protein 5 measurement	APOC4 MAP4K5	7.32e-04	9	135	2	EFO_0801520
Disease	migraine (is_implicated_in)	ESR1 MTHFR	7.32e-04	9	135	2	DOID:6364 (is_implicated_in)
Disease	thoracic aortic calcification measurement	COL6A6 VPS13A	7.32e-04	9	135	2	EFO_0010273
Disease	Thrombophilia	MTHFR SERPINA10	7.32e-04	9	135	2	C0398623
Disease	alpha-1-antitrypsin measurement	SERPINA2 SERPINA10	7.32e-04	9	135	2	EFO_0008327
Disease	Schizophrenia	DCDC2 RELN AHI1 ABCA13 ESR1 CHRNA5 JAG2 PBRM1 SERPINI1 PLAA MTHFR ERVK-8	7.66e-04	883	135	12	C0036341
Disease	Neoplasm of uncertain or unknown behavior of breast	ESR1 PBRM1 BRCA2	8.79e-04	41	135	3	C0496956
Disease	Breast adenocarcinoma	ESR1 PBRM1 BRCA2	8.79e-04	41	135	3	C0858252
Disease	quinone oxidoreductase-like protein 1 measurement	APOC4 MAP4K5	9.13e-04	10	135	2	EFO_0021880
Disease	Mood Disorders	RELN ESR1 DCTN1 MTHFR VPS13A	1.08e-03	168	135	5	C0525045
Disease	Hyperhomocysteinemia	NPHS1 MTHFR	1.11e-03	11	135	2	C0598608
Disease	level of Ceramide (d40:1) in blood serum	CYP7A1 MAP4K5	1.11e-03	11	135	2	OBA_2045185
Disease	mean reticulocyte volume	DPY19L3 ZFAT SAMD9 STXBP4 DNAH2 SERPINA2 PPP4R3A MTHFR MAP4K5 VPS13A TMEM131L	1.15e-03	799	135	11	EFO_0010701
Disease	Drugs used in diabetes use measurement	ACTN1 PPP4R3A RASGRP1 GSE1 MAP4K5 PAM	1.17e-03	255	135	6	EFO_0009924
Disease	cortical surface area measurement	TRPM6 OMA1 FILIP1 ANO2 RELN PDE3A SAMD9 NBEAL1 DENND3 PPP4R3A JAG2 ARL4C EXOC6B PAM DAAM1	1.29e-03	1345	135	15	EFO_0010736
Disease	complement component C7 measurement	MROH2B C6	1.33e-03	12	135	2	EFO_0008093
Disease	tumor protein p53-inducible protein 11 measurement	APOC4 MAP4K5	1.33e-03	12	135	2	EFO_0802169
Disease	inactive gamma-glutamyltranspeptidase 2 measurement	APOC4 MAP4K5	1.33e-03	12	135	2	EFO_0801692
Disease	fetal genotype effect measurement, body weights and measures	ESR1 ARHGAP26 SERPINA2	1.48e-03	49	135	3	EFO_0004324, EFO_0007959
Disease	velocity of sound measurement	ESR1 GPATCH1	1.57e-03	13	135	2	EFO_0005654
Disease	mood disorder	RELN PBRM1	1.57e-03	13	135	2	EFO_0004247
Disease	complement component C6 measurement	MROH2B C6	1.57e-03	13	135	2	EFO_0020281
Disease	apolipoprotein E measurement	APOC4 MAP4K5	1.57e-03	13	135	2	EFO_0008029
Disease	nephroblastoma (is_implicated_in)	BRCA2 MTHFR	1.82e-03	14	135	2	DOID:2154 (is_implicated_in)
Disease	triglycerides in medium HDL measurement	APOC4 MAP4K5 GKAP1	1.96e-03	54	135	3	EFO_0022321
Disease	body composition measurement	PDE3A NBEAL1 JAG2 MAP4K5 EXOC6B	1.98e-03	193	135	5	EFO_0005106
Disease	prostate cancer (is_implicated_in)	ESR1 CHUK BRCA2 CDC25A	2.08e-03	117	135	4	DOID:10283 (is_implicated_in)
Disease	response to beta blocker, heart rate	DNAH17 EXOC6B TMEM131L	2.29e-03	57	135	3	EFO_0004326, EFO_0007766
Disease	Intrahepatic cholestasis of pregnancy	CYP7A1 MAP4K5	2.39e-03	16	135	2	EFO_0009048
Disease	esophageal carcinoma, gastric carcinoma	RMDN2 EPG5	2.70e-03	17	135	2	EFO_0000178, EFO_0002916
Disease	Amyotrophic lateral sclerosis	SPG11 DCTN1	2.70e-03	17	135	2	cv:C0002736
Disease	hypertension	PDE3A ZFAT IRF5 PBRM1 MTHFR PLCB2	2.96e-03	307	135	6	EFO_0000537
Disease	non-alcoholic steatohepatitis (is_marker_for)	CYP7A1 IRF5	3.03e-03	18	135	2	DOID:0080547 (is_marker_for)
Disease	protein Z-dependent protease inhibitor measurement	SERPINA4 SERPINA10	3.03e-03	18	135	2	EFO_0021849
Disease	Cholecystitis	CYP7A1 MAP4K5	3.38e-03	19	135	2	HP_0001082
Disease	Breast Carcinoma	SYNE1 ESR1 STXBP4 JAG2 PBRM1 BRCA2 MTHFR DEK	3.41e-03	538	135	8	C0678222
Disease	MYELODYSPLASTIC SYNDROME	SAMD9 ARHGAP26 BRCA2	3.62e-03	67	135	3	C3463824
Disease	acetate measurement	SPG11 MAP4K5	3.74e-03	20	135	2	EFO_0010112
Disease	cortisol measurement	SERPINA2 SERPINA10	3.74e-03	20	135	2	EFO_0005843
Disease	attention deficit hyperactivity disorder (is_implicated_in)	DCDC2 MTHFR	3.74e-03	20	135	2	DOID:1094 (is_implicated_in)
Disease	lung non-small cell carcinoma (is_implicated_in)	ESR1 CHRNA5 PBRM1 PTPRB	3.88e-03	139	135	4	DOID:3908 (is_implicated_in)
Disease	susceptibility to mononucleosis measurement	DNAH2 MDN1 DNAH8	3.94e-03	69	135	3	EFO_0008403
Disease	response to ketamine	OMA1 ARHGAP26 MROH2B	3.94e-03	69	135	3	EFO_0009748
Disease	breast size	ESR1 SERPINA2 MAP4K5	3.94e-03	69	135	3	EFO_0004884
Disease	Deep Vein Thrombosis	MTHFR SERPINA10	4.12e-03	21	135	2	C0149871
Disease	BREAST CANCER	ESR1 BRCA2	4.12e-03	21	135	2	114480
Disease	Venous Thrombosis	MTHFR SERPINA10	4.12e-03	21	135	2	C0042487

Protein segments in the cluster

Peptide	Gene	Start	Entry
LTFKFDTVKSVLDKD	COP1	676	Q8NHY2
LVELKKLFDAKSEHL	EPG5	361	Q9HCE0
TTLKKEAKFELRAFH	AKAP2	171	Q9Y2D5
KVFQDKFDVTLLHTK	AVIL	366	O75366
SKLKEQIFEASKAHL	ERVK-19	591	O71037
SKLKEQIFEASKAHL	ERVK-8	591	Q902F8
TLSEIKALLKKHEAF	ACTN1	426	P12814
KALLKKHEAFESDLA	ACTN1	431	P12814
LEEAKTELHKVTKFA	ARL4C	101	P56559
ETFDFKIKFAETKAH	DCTN1	551	Q14203
KTKVRFEELLKTHSD	AHI1	11	Q8N157
SKFHKETLRFISTKL	AKAP8	411	O43823
TSKKRKVSLLFDHLE	RASGRP1	191	O95267
EEKKKFLTIFNLTHI	GSE1	861	Q14687
KIFELEKKTETAAHS	CEP55	201	Q53EZ4
KEIATLKKIDHFTFE	ABCA13	2571	Q86UQ4
LKKIDHFTFEKINDL	ABCA13	2576	Q86UQ4
FKTDTKEFVREIKHS	PAM	711	P19021
LKEIFDKIHSLLSGK	GLE1	441	Q53GS7
LKDFHSEDHISKKTE	GKAP1	181	Q5VSY0
LNLKSDEHIFKFLKA	DPY19L3	366	Q6ZPD9
FLESKDSLLKKTHSL	APOC4	101	P55056
KEKSLLVDFFLKEEH	ANO2	941	Q9NQ90
SDKETLAFHLEKVKD	CCDC180	576	Q9P1Z9
VDSHIKDFAAKLSLI	DENND3	141	A2RUS2
KDLKEKDLHSIFTHD	DBF4	516	Q9UBU7
DGHEEALSKFTLKKL	ASPM	876	Q8IZT6
NKETEEIHLFFAKKL	ARHGEF9	396	O43307
KELKKFSLTSELLDS	AP4E1	841	Q9UPM8
RFIAKVLKDSLHEKF	IQGAP1	1161	P46940
SKLFVVSHDAKLLFS	NBEAL1	2401	Q6ZS30
EKTTLKDKNALHLFS	NBEAL1	2561	Q6ZS30
HKDTKIEKEEKDSFF	RAD51AP2	851	Q09MP3
QFVITLKKAEHLDFK	RANBP2	3171	P49792
KELDTFKSVKLALEH	ODF2L	101	Q9ULJ1
FLKSDLFLKHKRTEE	RGS10	146	O43665
TSHFTKKIKESLECF	PIK3C2G	1151	O75747
HREFLTKTAKFKEVI	PPP4R3A	236	Q6IN85
FTEKNLKALLKHFDL	MSL3P1	396	P0C860
HETLFKTKKLSEAES	LTN1	801	O94822
LVAKSDVETAKKIHF	RADIL	1056	Q96JH8
SEAFTKETFKKSLIL	NPHS1	421	O60500
SFEADLKHLKEKVSA	MTHFR	206	P42898
LLLIHKSLSKDAKEF	PTPRB	506	P23467
HLATRKFLEKEVFKS	PBRM1	1006	Q86U86
HKLSFLKKIFNSDEL	MDN1	201	Q9NU22
FLKHITSEEFSALKT	MTMR14	396	Q8NCE2
VLESLIKDHKDFSKT	DST	4881	Q03001
LKAKLEFFHKSIQLD	CHUK	476	O15111
LEAEKFLSHKFTKDP	JAG2	1191	Q9Y219
KRKVFSKIFSHEALE	CYP26B1	141	Q9NR63
KEELLHSEKLKTYFE	DDX56	451	Q9NY93
SLEKVLVEFSHKELF	COMMD10	171	Q9Y6G5
TSKHEKKEDSISEFL	GPATCH1	686	Q9BRR8
FLSSTLKSLEEKDHI	ESR1	461	P03372
KLLVSFHDRKEVAKF	ITGB6	731	P18564
LATDLKKHFDFVAKF	PDE3A	906	Q14432
THDLSKFDRVKFETL	DNAH8	1741	Q96JB1
HKLTLDEKKKFLFFL	HERC6	936	Q8IVU3
SFSEKNLKALLKHFD	MSL3	471	Q8N5Y2
LFERIKKKKHFSETE	RPS6KA5	506	O75582
DLKDFLESIRKHSDK	EXOC6B	201	Q9Y2D4
KTKLFSLEHFLNELI	IRF5	366	Q13568
ASSEELFLKVHKKAT	NUDT7	221	P0C024
SVFSKRHAKLELDEK	MSL1	501	Q68DK7
SKLKEQIFEASKAHL	ERVK-7	1351	P63135
KKEALKSIHYLEDAF	CCDC182	66	A6NF36
KLKLHTFESHKDEIF	RBBP7	306	Q16576
HTLKTFLKERFDSEE	RELN	2886	P78509
GALLTKTKKFDELLH	PANK4	226	Q9NVE7
LKSEEEKTEFFKFLL	SCYL3	261	Q8IZE3
SFLKKIIKDHQESLD	CYP2U1	296	Q7Z449
LAEAKDLFTKAVKHF	DAAM1	946	Q9Y4D1
KLVDTFLEDTKKLYH	SERPINA2	151	P20848
SSIAKHEDSLLKDLF	CHRNA5	41	P30532
ELEKEFHCKKYLSLT	GBX2	261	P52951
LEKEFHCKKYLSLTE	GBX1	276	Q14549
ESALKETKGFLDKLH	IFT57	276	Q9NWB7
HETIKKVKDIFTDSF	BRCA2	1856	P51587
TTKAKDLHLSDVFLK	C6	326	P13671
TFLDSLKKFDKEHIP	DNAH17	3196	Q9UFH2
SKLKEQIFEASKAHL	ERVK-6	591	Q69384
FHTEFTIKEISLDLK	COG3	626	Q96JB2
IERIHFFLSKKKTDE	DEK	91	P35659
SKLSEDDTTHFKLPK	DNAH14	401	Q0VDD8
KHFEDKTLKSDLSHT	CEP192	181	Q8TEP8
LLFKEIDKKSDFEFT	KIF4A	121	O95239
LLFKEIDKKSDFEFT	KIF4B	121	Q2VIQ3
TLSTFDDLEKAKTHL	CYP7A1	266	P22680
SKLKEQIFEASKAHL	HERVK_113	591	Q902F9
AELKYELHLKSFEKA	FKBP4	241	Q02790
ISHFKQSAEKLIEEK	DDX21	591	Q9NR30
FKKKAHTLLEDFEFK	DNAH2	1156	Q9P225
DSKFLLKTFTHIKSN	INPP5F	126	Q9Y2H2
IHEKKVSSFEVFLKE	DCDC2	36	Q9UHG0
TAEKKLTVHNFDELK	COL6A6	1151	A6NMZ7
LKSSKKLASELSFDF	MAP4K5	756	Q9Y4K4
HEDFKEDLKKFRTKS	CDC25A	491	P30304
SDLLSEFKKHDADKV	PPEF2	571	O14830
KVVKTLKFFDLHETG	NXPE1	366	Q8N323
LKEYFTSLTKHLKRD	UPF2	356	Q9HAU5
SDNKEIFLSKAIHKS	SERPINI1	326	Q99574
SNKKKFEDALSLIHS	PLEKHM2	986	Q8IWE5
AVSFFKKTVLHKELV	TDRD6	616	O60522
SFKLEEKTAHSSLAL	SPRYD4	31	Q8WW59
LKKIHSSDFSLVKTD	SYNE1	2156	Q8NF91
KFTKAKELISADLEH	SYNE1	4951	Q8NF91
AHLKKSKESESFVFF	TMEM131L	566	A2VDJ0
ELSLKDDLTKLKSFT	FILIP1	491	Q7Z7B0
HVERKSLEFAKSKLE	RASGRF2	406	O14827
FSLEELKKSYHLNKS	SAMD9	991	Q5K651
KLEASKSFHKATLDV	SERPINA4	356	P29622
TLKSHEAELDKTNKF	ARHGAP26	21	Q9UNA1
FSLDAVKFLLEAKHL	SLC3A1	311	Q07837
KSESFELLRDHKEKF	RMDN2	196	Q96LZ7
GLLEEHKEFLKKFSV	SLF2	716	Q8IX21
HKEFLKKFSVTIDAI	SLF2	721	Q8IX21
FAEEIKKSLISFLLH	MROH2B	1426	Q7Z745
KTFEASTEKLLHFVE	STXBP4	421	Q6ZWJ1
LFKLSTKHFLEESEK	OMA1	476	Q96E52
EKIKHFSQLKSELFL	C12orf56	326	Q8IXR9
LTFSKEKEEFIHSRL	COA8	116	Q96IL0
QDFFKHKSVLDSFLK	SPG11	821	Q96JI7
NEHDLLKLKKFTEDF	VPS4B	426	O75351
IKYNDDDHKTLFLKT	ZBTB14	11	O43829
EKSFSEDRLIKSHIK	ZFAT	836	Q9P243
EAEATFKSLVKTHEK	UBE2QL1	136	A1L167
KFSHDDLTKETKKLL	ZC3H6	346	P61129
LLKTFEALKFFVHLK	VPS13A	481	Q96RL7
IAKSSLKTESLDFHL	TMIGD1	196	Q6UXZ0
LKTESLDFHLIVKDK	TMIGD1	201	Q6UXZ0
ERLKATLTKKESFLH	TRAV20	81	A0A0B4J274
LYLSKEDLKKLHDFE	TRPM6	1136	Q9BX84
HKILKDKLTSDFEEI	RINT1	221	Q6NUQ1
FLKLKDLTSSDTFKE	RYR3	3916	Q15413
SVEALLKKHEDFEKS	SPTAN1	501	Q13813
KAFEKELSHATIDSK	PLAA	311	Q9Y263
EERIFNFHTDKKSLK	ZNF470	196	Q6ECI4
LKFHTLDSYEDKQKL	YJU2B	231	P13994
KFFSAHDTKSVKLKE	PLCB2	821	Q00722
TEVDTFHLDKYKTIK	SERPINA10	251	Q9UK55
KFLSSSFSVLKDHIK	ZNF507	131	Q8TCN5
SKHEFQAETKKLLDI	TRAP1	86	Q12931
FKEATHLFSDLNKLK	TOPBP1	1431	Q92547
KFEKRHIEIFTDLSS	XRCC5	126	P13010
KCKKFFSDVSILDLH	ZNF284	151	Q2VY69
SLKDVKYDDKVFSHL	DYNLT2	111	Q8IZS6
DAKKSKFILLHFSTF	KCNH8	206	Q96L42
LDTSKLSHKFKELQI	PPP1R9A	671	Q9ULJ8