Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentendolysosome membrane

CLEC16A TLR9

1.47e-0420192GO:0036020
GeneOntologyCellularComponentendolysosome

CLEC16A TLR9

3.35e-0430192GO:0036019
GeneOntologyCellularComponentendosome

PACSIN3 MYO5B CLEC16A SIGLEC1 PLD1 TLR9

4.32e-041167196GO:0005768
GeneOntologyCellularComponentlysosomal membrane

CLEC16A PLD1 TLR9 LRBA

7.01e-04462194GO:0005765
GeneOntologyCellularComponentlytic vacuole membrane

CLEC16A PLD1 TLR9 LRBA

7.01e-04462194GO:0098852
GeneOntologyCellularComponentvacuolar membrane

CLEC16A PLD1 TLR9 LRBA

9.92e-04507194GO:0005774
GeneOntologyCellularComponentendosome membrane

MYO5B CLEC16A PLD1 TLR9

1.87e-03602194GO:0010008
GeneOntologyCellularComponenttertiary granule membrane

PLAU PLD1

1.98e-0373192GO:0070821
GeneOntologyCellularComponentspecific granule membrane

PLAU PLD1

3.05e-0391192GO:0035579
GeneOntologyCellularComponentlate endosome

CLEC16A SIGLEC1 PLD1

3.64e-03348193GO:0005770
GeneOntologyCellularComponentcytoplasmic vesicle membrane

MYO5B CLEC16A PLAU PLD1 TLR9

5.27e-031307195GO:0030659
GeneOntologyCellularComponentlysosome

CLEC16A PLD1 TLR9 LRBA

5.47e-03811194GO:0005764
GeneOntologyCellularComponentlytic vacuole

CLEC16A PLD1 TLR9 LRBA

5.47e-03811194GO:0000323
GeneOntologyCellularComponentvesicle membrane

MYO5B CLEC16A PLAU PLD1 TLR9

5.59e-031325195GO:0012506
GeneOntologyCellularComponentGolgi apparatus subcompartment

PACSIN3 PLD1 LRBA

7.12e-03443193GO:0098791
GeneOntologyCellularComponentvacuole

CLEC16A PLD1 TLR9 LRBA

8.29e-03913194GO:0005773
GeneOntologyCellularComponentserine/threonine protein kinase complex

GTF2H2 TRIM40

8.81e-03157192GO:1902554
GeneOntologyCellularComponentspecific granule

PLAU PLD1

9.14e-03160192GO:0042581
GeneOntologyCellularComponenttertiary granule

PLAU PLD1

9.58e-03164192GO:0070820
GeneOntologyCellularComponentprotein kinase complex

GTF2H2 TRIM40

1.03e-02170192GO:1902911
HumanPhenoVillous atrophy

MYO5B LRBA

2.29e-042552HP:0011473
HumanPhenoAbnormal small intestinal villus morphology

MYO5B LRBA

2.29e-042552HP:0011472
HumanPhenoAbnormal small intestinal mucosa morphology

MYO5B LRBA

2.88e-042852HP:0025129
DomainLRR_6

CARMIL3 TLR9

1.41e-0355192PF13516
DomainIg_I-set

MYOM1 SIGLEC1

1.57e-02190192IPR013098
Domainig

MYOM1 SIGLEC1

1.57e-02190192PF00047
DomainImmunoglobulin

MYOM1 SIGLEC1

1.57e-02190192IPR013151
DomainI-set

MYOM1 SIGLEC1

1.57e-02190192PF07679
Pubmed

Host response. Inflammation-induced disruption of SCS macrophages impairs B cell responses to secondary infection.

SIGLEC1 TLR9

7.90e-06819225657250
Pubmed

Squalene emulsion-based vaccine adjuvants stimulate CD8 T cell, but not antibody responses, through a RIPK3-dependent pathway.

SIGLEC1 TLR9

2.56e-051419232515732
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

PACSIN3 OGFOD1 RSAD1 GTF2H2 CTNNAL1

4.41e-04124219530973865
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

MYOM1 SIGLEC1

5.76e-03161132593
GeneFamilyADAM metallopeptidase domain containing|CD molecules

SIGLEC1 TLR9

3.15e-02394132471
CoexpressionKOINUMA_TARGETS_OF_SMAD2_OR_SMAD3

MYO5B PLAU GTF2H2 BTG1 CTNNAL1 PLD1

2.06e-05843196M2356
Diseasesinusitis (is_marker_for)

PLAU TLR9

4.75e-0518172DOID:0050127 (is_marker_for)
Diseasesquamous cell carcinoma (is_marker_for)

PLAU TLR9

5.31e-0519172DOID:1749 (is_marker_for)
DiseaseMiddle Cerebral Artery Embolus

PLAU PLD1

1.73e-0434172C0751845
DiseaseEmbolic Infarction, Middle Cerebral Artery

PLAU PLD1

1.73e-0434172C0751847
DiseaseLeft Middle Cerebral Artery Infarction

PLAU PLD1

1.73e-0434172C0751846
DiseaseRight Middle Cerebral Artery Infarction

PLAU PLD1

1.73e-0434172C0751849
DiseaseThrombotic Infarction, Middle Cerebral Artery

PLAU PLD1

1.73e-0434172C0751848
DiseaseMiddle Cerebral Artery Syndrome

PLAU PLD1

1.73e-0434172C0238281
DiseaseMiddle Cerebral Artery Occlusion

PLAU PLD1

1.73e-0434172C0740391
DiseaseInfarction, Middle Cerebral Artery

PLAU PLD1

1.73e-0434172C0740392
DiseaseMiddle Cerebral Artery Thrombosis

PLAU PLD1

1.73e-0434172C0740376
Diseaseasthma (is_marker_for)

PLAU TLR9

2.36e-03126172DOID:2841 (is_marker_for)
Diseaserenal cell carcinoma (is_marker_for)

PLAU TLR9

2.43e-03128172DOID:4450 (is_marker_for)
Diseaseneurodegenerative disease (implicated_via_orthology)

PACSIN3 CLEC16A

3.11e-03145172DOID:1289 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
SANYDVELLHHKDAH

INTS13

276

Q9NVM9
HYTLIHDHSKAEFAL

OGFOD1

446

Q8N543
HDHSKAEFALDLILY

OGFOD1

451

Q8N543
LQELYHSHKSLARHL

CARMIL3

846

Q8ND23
SDLFLAEHHKLLLYD

LRBA

396

P50851
YADTLNHLEKSLAHL

NBAS

1951

A2RRP1
ATQLAADLLKYHADH

CTNNAL1

401

Q9UBT7
QHLDLSSSEKFHELH

PACSIN3

251

Q9UKS6
LHHCDDHLSLYQLSL

RSAD1

216

Q9HA92
VILDESHYKELLTHH

GTF2H2C;

221

Q6P1K8
SHHELTIENALSHYK

TRIM40

101

Q6P9F5
LHKDYSADTLAHHND

PLAU

261

P00749
SLYKQLHRHHLHDAD

PLD1

561

Q13393
SHHHVICQLLSDYKE

POTEJ

311

P0CG39
SQSLQELLAEHYKHH

BTG1

41

P62324
SDLVAEHLDHLHYLN

CLEC16A

251

Q2KHT3
LDLSHNKLDLYHEHS

TLR9

526

Q9NR96
VILDESHYKELLTHH

GTF2H2

221

Q13888
YKNHVLLEDAHSHTL

SIGLEC1

361

Q9BZZ2
HADYTNDDLKVHSLL

MYO5B

1511

Q9ULV0
TETYHAKLNEDHLLH

MYOM1

261

P52179