Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	Anion_exchange_CS	SLC4A3 SLC4A2	3.14e-05	3	61	2	IPR018241
Domain	Anion_exchange	SLC4A3 SLC4A2	1.04e-04	5	61	2	IPR001717
Domain	DNA/RNA_helicase_DEAH_CS	DHX38 CHD2 DHX33	2.01e-04	35	61	3	IPR002464
Domain	ANION_EXCHANGER_2	SLC4A3 SLC4A2	2.18e-04	7	61	2	PS00220
Domain	ANION_EXCHANGER_1	SLC4A3 SLC4A2	2.18e-04	7	61	2	PS00219
Domain	DEAH_ATP_HELICASE	DHX38 CHD2 DHX33	2.58e-04	38	61	3	PS00690
Domain	DHC_N1	DNAH8 DNAH11	2.90e-04	8	61	2	PF08385
Domain	Dynein_heavy_dom-1	DNAH8 DNAH11	2.90e-04	8	61	2	IPR013594
Domain	Band3_cytoplasmic_dom	SLC4A3 SLC4A2	3.72e-04	9	61	2	IPR013769
Domain	Band_3_cyto	SLC4A3 SLC4A2	3.72e-04	9	61	2	PF07565
Domain	-	SLC4A3 SLC4A2	3.72e-04	9	61	2	3.40.1100.10
Domain	HCO3_cotransp	SLC4A3 SLC4A2	4.64e-04	10	61	2	PF00955
Domain	HCO3_transpt_C	SLC4A3 SLC4A2	4.64e-04	10	61	2	IPR011531
Domain	PTrfase/Anion_transptr	SLC4A3 SLC4A2	4.64e-04	10	61	2	IPR016152
Domain	HCO3_transpt_euk	SLC4A3 SLC4A2	4.64e-04	10	61	2	IPR003020
Domain	Dynein_heavy_chain_D4_dom	DNAH8 DNAH11	9.31e-04	14	61	2	IPR024317
Domain	Dynein_HC_stalk	DNAH8 DNAH11	9.31e-04	14	61	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH8 DNAH11	9.31e-04	14	61	2	IPR013602
Domain	DHC_N2	DNAH8 DNAH11	9.31e-04	14	61	2	PF08393
Domain	MT	DNAH8 DNAH11	9.31e-04	14	61	2	PF12777
Domain	AAA_8	DNAH8 DNAH11	9.31e-04	14	61	2	PF12780
Domain	ATPase_dyneun-rel_AAA	DNAH8 DNAH11	9.31e-04	14	61	2	IPR011704
Domain	AAA_5	DNAH8 DNAH11	9.31e-04	14	61	2	PF07728
Domain	DHC_fam	DNAH8 DNAH11	1.07e-03	15	61	2	IPR026983
Domain	Dynein_heavy_dom	DNAH8 DNAH11	1.07e-03	15	61	2	IPR004273
Domain	Dynein_heavy	DNAH8 DNAH11	1.07e-03	15	61	2	PF03028
Domain	DUF1605	DHX38 DHX33	1.38e-03	17	61	2	IPR011709
Domain	OB_NTP_bind	DHX38 DHX33	1.38e-03	17	61	2	PF07717
Domain	HA2	DHX38 DHX33	1.55e-03	18	61	2	SM00847
Domain	HA2	DHX38 DHX33	1.55e-03	18	61	2	PF04408
Domain	Helicase-assoc_dom	DHX38 DHX33	1.55e-03	18	61	2	IPR007502
Domain	Helicase_C	DHX38 CHD2 DHX33	5.17e-03	107	61	3	PF00271
Domain	HELICc	DHX38 CHD2 DHX33	5.17e-03	107	61	3	SM00490
Domain	Helicase_C	DHX38 CHD2 DHX33	5.31e-03	108	61	3	IPR001650
Domain	HELICASE_CTER	DHX38 CHD2 DHX33	5.44e-03	109	61	3	PS51194
Domain	HELICASE_ATP_BIND_1	DHX38 CHD2 DHX33	5.44e-03	109	61	3	PS51192
Domain	DEXDc	DHX38 CHD2 DHX33	5.44e-03	109	61	3	SM00487
Domain	Helicase_ATP-bd	DHX38 CHD2 DHX33	5.58e-03	110	61	3	IPR014001
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	PTPN2 DLG5 YBX1 CSNK1D CSNK1E TECR DHX38 TIMM50 RBM14 USP7 ITGA6 PPHLN1	1.60e-06	1257	61	12	36526897
Pubmed	Association of CPI-17 with protein kinase C and casein kinase I.	ADAP1 CSNK1D CSNK1E	2.30e-06	15	61	3	15003508
Pubmed	USP7 Is a Tumor-Specific WNT Activator for APC-Mutated Colorectal Cancer by Mediating β-Catenin Deubiquitination.	CSNK1D CSNK1E USP7	2.83e-06	16	61	3	29045831
Pubmed	Casein kinase I delta/epsilon phosphorylates topoisomerase IIalpha at serine-1106 and modulates DNA cleavage activity.	CSNK1D CSNK1E	3.03e-06	2	61	2	19043076
Pubmed	CK1δ and CK1ε are components of human 40S subunit precursors required for cytoplasmic 40S maturation.	CSNK1D CSNK1E	3.03e-06	2	61	2	24424021
Pubmed	Human intestinal anion exchanger isoforms: expression, distribution, and membrane localization.	SLC4A3 SLC4A2	3.03e-06	2	61	2	11248201
Pubmed	Regulation of casein kinase I epsilon and casein kinase I delta by an in vivo futile phosphorylation cycle.	CSNK1D CSNK1E	3.03e-06	2	61	2	9632646
Pubmed	Effects of altered expression and activity levels of CK1δ and ɛ on tumor growth and survival of colorectal cancer patients.	CSNK1D CSNK1E	3.03e-06	2	61	2	25404202
Pubmed	An evaluation of polymorphisms in casein kinase 1 delta and epsilon genes in major psychiatric disorders.	CSNK1D CSNK1E	3.03e-06	2	61	2	22981886
Pubmed	cDNA cloning and tissue distribution of mRNAs for two proteins that are related to the band 3 Cl-/HCO3- exchanger.	SLC4A3 SLC4A2	3.03e-06	2	61	2	2294114
Pubmed	Targeting of the circadian clock via CK1δ/ε to improve glucose homeostasis in obesity.	CSNK1D CSNK1E	9.07e-06	3	61	2	27439882
Pubmed	EFR3s are palmitoylated plasma membrane proteins that control responsiveness to G-protein-coupled receptors.	EFR3B EFR3A	9.07e-06	3	61	2	25380825
Pubmed	CKIepsilon/delta-dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clock.	CSNK1D CSNK1E	9.07e-06	3	61	2	19805222
Pubmed	Centrosomal anchoring of the protein kinase CK1delta mediated by attachment to the large, coiled-coil scaffolding protein CG-NAP/AKAP450.	CSNK1D CSNK1E	9.07e-06	3	61	2	12270714
Pubmed	Expression and function of bicarbonate/chloride exchangers in the preimplantation mouse embryo.	SLC4A3 SLC4A2	9.07e-06	3	61	2	7592657
Pubmed	Casein kinase 1 proteomics reveal prohibitin 2 function in molecular clock.	CSNK1D CSNK1E	9.07e-06	3	61	2	22384121
Pubmed	Pendrin: an apical Cl-/OH-/HCO3- exchanger in the kidney cortex.	SLC4A3 SLC4A2	9.07e-06	3	61	2	11208611
Pubmed	Gene expression levels of Casein kinase 1 (CK1) isoforms are correlated to adiponectin levels in adipose tissue of morbid obese patients and site-specific phosphorylation mediated by CK1 influences multimerization of adiponectin.	CSNK1D CSNK1E	9.07e-06	3	61	2	25724478
Pubmed	A comparative study of structural and conformational properties of casein kinase-1 isoforms: insights from molecular dynamics and principal component analysis.	CSNK1D CSNK1E	9.07e-06	3	61	2	25665722
Pubmed	CRISPR-mediated gene targeting of CK1δ/ε leads to enhanced understanding of their role in endocytosis via phosphoregulation of GAPVD1.	CSNK1D CSNK1E	9.07e-06	3	61	2	32321936
Pubmed	Casein kinase 1-epsilon or 1-delta required for Wnt-mediated intestinal stem cell maintenance.	CSNK1D CSNK1E	9.07e-06	3	61	2	28963394
Pubmed	Human Rad17 C-terminal tail is phosphorylated by concerted action of CK1δ/ε and CK2 to promote interaction with the 9-1-1 complex.	CSNK1D CSNK1E	9.07e-06	3	61	2	31353086
Pubmed	Sequence analysis of the cDNA for the human casein kinase I delta (CSNK1D) gene and its chromosomal localization.	CSNK1D CSNK1E	9.07e-06	3	61	2	8786104
Pubmed	CK1δ/ε protein kinase primes the PER2 circadian phosphoswitch.	CSNK1D CSNK1E	1.81e-05	4	61	2	29784789
Pubmed	Identification of an apical Cl(-)/HCO3(-) exchanger in the small intestine.	SLC4A3 SLC4A2	1.81e-05	4	61	2	11842009
Pubmed	Involvement of casein kinase 1 epsilon/delta (Csnk1e/d) in the pathogenesis of familial Parkinson's disease caused by CHCHD2.	CSNK1D CSNK1E	1.81e-05	4	61	2	37578019
Pubmed	Casein kinase 1 delta functions at the centrosome to mediate Wnt-3a-dependent neurite outgrowth.	CSNK1D CSNK1E	1.81e-05	4	61	2	21422228
Pubmed	Stabilization of KPNB1 by deubiquitinase USP7 promotes glioblastoma progression through the YBX1-NLGN3 axis.	YBX1 USP7	1.81e-05	4	61	2	38254206
Pubmed	The DNA-binding activity of mouse DNA methyltransferase 1 is regulated by phosphorylation with casein kinase 1delta/epsilon.	CSNK1D CSNK1E	1.81e-05	4	61	2	20192920
Pubmed	Therapeutic Targeting of Casein Kinase 1δ/ε in an Alzheimer's Disease Mouse Model.	CSNK1D CSNK1E	1.81e-05	4	61	2	31334659
Pubmed	p53 is phosphorylated in vitro and in vivo by the delta and epsilon isoforms of casein kinase 1 and enhances the level of casein kinase 1 delta in response to topoisomerase-directed drugs.	CSNK1D CSNK1E	1.81e-05	4	61	2	9349507
Pubmed	Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family.	CSNK1D CSNK1E	1.81e-05	4	61	2	7797465
Pubmed	Casein kinase 1 delta (CK1delta) regulates period length of the mouse suprachiasmatic circadian clock in vitro.	CSNK1D CSNK1E	1.81e-05	4	61	2	20421981
Pubmed	Involvement of casein kinase Iepsilon in cytokine-induced granulocytic differentiation.	CSNK1D CSNK1E	1.81e-05	4	61	2	15070676
Pubmed	PTEN phosphorylation and nuclear export mediate free fatty acid-induced oxidative stress.	WWP2 USP7	1.81e-05	4	61	2	24063548
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	DLG5 YBX1 CSNK1D WWP2 TECR YLPM1 TIMM50 RBM14 PPHLN1 CHD2 POTEJ	2.34e-05	1371	61	11	36244648
Pubmed	Phosphorylation of human enhancer filamentation 1 (HEF1) stimulates interaction with Polo-like kinase 1 leading to HEF1 localization to focal adhesions.	CSNK1D CSNK1E	3.02e-05	5	61	2	29191835
Pubmed	The leukodystrophy protein FAM126A (hyccin) regulates PtdIns(4)P synthesis at the plasma membrane.	EFR3B EFR3A	3.02e-05	5	61	2	26571211
Pubmed	Control of intracellular dynamics of mammalian period proteins by casein kinase I epsilon (CKIepsilon) and CKIdelta in cultured cells.	CSNK1D CSNK1E	3.02e-05	5	61	2	11865049
Pubmed	Casein kinase 1 delta regulates the pace of the mammalian circadian clock.	CSNK1D CSNK1E	3.02e-05	5	61	2	19414593
Pubmed	Semisynthetic Approach to the Analysis of Tumor Suppressor PTEN Ubiquitination.	WWP2 USP7	3.02e-05	5	61	2	36897111
Pubmed	Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I epsilon.	CSNK1D CSNK1E	3.02e-05	5	61	2	10848614
Pubmed	The extracellular matrix dimension of skeletal muscle development.	ITGA6 PAX3	3.02e-05	5	61	2	21420400
Pubmed	Aberrant lipid accumulation in the mouse visceral yolk sac resulting from maternal diabetes and obesity.	SCARB1 CUBN	3.02e-05	5	61	2	36936697
Pubmed	Desynchrony between brain and peripheral clocks caused by CK1δ/ε disruption in GABA neurons does not lead to adverse metabolic outcomes.	CSNK1D CSNK1E	3.02e-05	5	61	2	29463694
Pubmed	Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin.	CSNK1D CSNK1E	3.02e-05	5	61	2	17027228
Pubmed	The CK1δ/ε-AES axis regulates tumorigenesis and metastasis in colorectal cancer.	CSNK1D CSNK1E	3.02e-05	5	61	2	33754069
Pubmed	Essential roles of CKIdelta and CKIepsilon in the mammalian circadian clock.	CSNK1D CSNK1E	3.02e-05	5	61	2	19948962
Pubmed	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	TTLL5 EFR3B WDFY3 MYRF	3.20e-05	102	61	4	10231032
Pubmed	Association of genetic variation in genes implicated in the beta-catenin destruction complex with risk of breast cancer.	CSNK1D CSNK1E	4.52e-05	6	61	2	18708403
Pubmed	A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP).	CSNK1D CSNK1E	4.52e-05	6	61	2	20048001
Pubmed	Phosphorylation at Ser244 by CK1 determines nuclear localization and substrate targeting of PKD2.	CSNK1D CSNK1E	4.52e-05	6	61	2	17962809
Pubmed	Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex.	CSNK1D CSNK1E	4.52e-05	6	61	2	11818547
Pubmed	Physiological role for casein kinase 1 in glutamatergic synaptic transmission.	CSNK1D CSNK1E	4.52e-05	6	61	2	16014721
Pubmed	Identification of a novel Wnt5a-CK1ɛ-Dvl2-Plk1-mediated primary cilia disassembly pathway.	CSNK1D CSNK1E	4.52e-05	6	61	2	22609948
Pubmed	High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinase.	CSNK1D CSNK1E	4.52e-05	6	61	2	21179498
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	TBC1D8 PTPN2 DLG5 CSNK1E WWP2 TECR TTLL5 TIMM50 EFR3B SLC4A2 EFR3A	4.91e-05	1487	61	11	33957083
Pubmed	Integrin expression patterns during early limb muscle development in the mouse.	ITGA6 PAX3	6.32e-05	7	61	2	14516674
Pubmed	SPOP-mediated ubiquitination and degradation of PDK1 suppresses AKT kinase activity and oncogenic functions.	CSNK1D CSNK1E	6.32e-05	7	61	2	34353330
Pubmed	Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.	DNAH8 DNAH11	6.32e-05	7	61	2	9256245
Pubmed	Mapping of mouse gamma crystallin genes on chromosome 1.	CRYGA PAX3	6.32e-05	7	61	2	3242494
Pubmed	Modeling of a human circadian mutation yields insights into clock regulation by PER2.	CSNK1D CSNK1E	6.32e-05	7	61	2	17218255
Pubmed	Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway.	CSNK1D CSNK1E	6.32e-05	7	61	2	12000790
Pubmed	Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.	DNAH8 DNAH11	6.32e-05	7	61	2	31178125
Pubmed	PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identity.	EFR3B EFR3A	6.32e-05	7	61	2	23229899
Pubmed	SCFFBW7-mediated degradation of Brg1 suppresses gastric cancer metastasis.	CSNK1D CSNK1E	6.32e-05	7	61	2	30177679
Pubmed	Chloride Accumulators NKCC1 and AE2 in Mouse GnRH Neurons: Implications for GABAA Mediated Excitation.	SLC4A3 SLC4A2	8.42e-05	8	61	2	26110920
Pubmed	p57Kip2 expression is enhanced during mid-cardiac murine development and is restricted to trabecular myocardium.	YBX1 PAX3	8.42e-05	8	61	2	10231856
Pubmed	Regulation of Connexin32 by ephrin receptors and T-cell protein-tyrosine phosphatase.	MST1R PTPN2	8.42e-05	8	61	2	30401746
Pubmed	Casein kinase 1 delta (CK1delta) interacts with the SNARE associated protein snapin.	CSNK1D CSNK1E	8.42e-05	8	61	2	17101137
Pubmed	The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1.	CSNK1D CSNK1E	8.42e-05	8	61	2	21930935
Pubmed	Chromosomal location of the murine anion exchanger genes encoding AE2 and AE3.	SLC4A3 SLC4A2	8.42e-05	8	61	2	7894173
Pubmed	Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism.	CSNK1D CSNK1E	8.42e-05	8	61	2	17244647
Pubmed	Deubiquitylase OTUD3 regulates PTEN stability and suppresses tumorigenesis.	WWP2 USP7	8.42e-05	8	61	2	26280536
Pubmed	Dysbindin structural homologue CK1BP is an isoform-selective binding partner of human casein kinase-1.	CSNK1D CSNK1E	8.42e-05	8	61	2	16618118
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	YBX1 YLPM1 TIMM50 RBM14 PPHLN1 RUNX1T1	8.42e-05	411	61	6	35182466
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PTPN2 DHX38 YLPM1 TIMM50 USP7 EFR3B ITGA6 PLK4 EFR3A	8.47e-05	1049	61	9	27880917
Pubmed	The Prader-Willi syndrome proteins MAGEL2 and necdin regulate leptin receptor cell surface abundance through ubiquitination pathways.	VPS52 USP7	1.08e-04	9	61	2	28973533
Pubmed	Screen for genes regulated during early kidney morphogenesis.	CSNK1D ITGA6	1.08e-04	9	61	2	10322635
Pubmed	SDCBP promotes pancreatic cancer progression by preventing YAP1 from β-TrCP-mediated proteasomal degradation.	CSNK1D CSNK1E	1.08e-04	9	61	2	36828627
Pubmed	Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase.	CSNK1D CSNK1E	1.08e-04	9	61	2	20708156
Pubmed	Biological, clinical and population relevance of 95 loci for blood lipids.	SCARB1 NCAN DHX38 DNAH11	1.29e-04	146	61	4	20686565
Pubmed	The centrosomal protein C-Nap1 is required for cell cycle-regulated centrosome cohesion.	CSNK1D CSNK1E PLK4	1.33e-04	56	61	3	11076968
Pubmed	Phosphorylation of LRRK2 by casein kinase 1α regulates trans-Golgi clustering via differential interaction with ARHGEF7.	CSNK1D CSNK1E	1.35e-04	10	61	2	25500533
Pubmed	Integrin-Mediated Focal Anchorage Drives Epithelial Zippering during Mouse Neural Tube Closure.	ITGA6 PAX3	1.35e-04	10	61	2	32049039
Pubmed	The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation.	CSNK1D CSNK1E PLK4	1.40e-04	57	61	3	16462731
Pubmed	Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation.	CSNK1D CSNK1E PLK4	1.48e-04	58	61	3	12852856
Pubmed	Lysosomal protein transmembrane 5 promotes lung-specific metastasis by regulating BMPR1A lysosomal degradation.	WWP2 TECR	1.65e-04	11	61	2	35842443
Pubmed	Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function.	CSNK1D CSNK1E PLK4	1.72e-04	61	61	3	7790358
Pubmed	USP9X Deubiquitylates DVL2 to Regulate WNT Pathway Specification.	CSNK1D CSNK1E WWP2	1.80e-04	62	61	3	31340145
Pubmed	Ubiquitin-assisted phase separation of dishevelled-2 promotes Wnt signalling.	CSNK1D CSNK1E WWP2 USP7	1.88e-04	161	61	4	36398662
Pubmed	TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.	MST1R TECR SCARB1 ITGA6	2.02e-04	164	61	4	32409323
Pubmed	Identification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1.	CSNK1D WWP2 USP7	2.08e-04	65	61	3	18729074
Pubmed	Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex.	CSNK1D CSNK1E PLK4	2.17e-04	66	61	3	12221128
Pubmed	Clock genes may influence bipolar disorder susceptibility and dysfunctional circadian rhythm.	CSNK1D CSNK1E	2.33e-04	13	61	2	18228528
Pubmed	A molecular mechanism for circadian clock negative feedback.	CSNK1D CSNK1E	2.33e-04	13	61	2	21680841
Pubmed	Proximity labeling reveals dynamic changes in the SQSTM1 protein network.	YBX1 CSNK1D CSNK1E TIMM50 TTC9C	2.57e-04	322	61	5	39098523
Pubmed	Viral protein engagement of GBF1 induces host cell vulnerability through synthetic lethality.	YBX1 RBM14 DHX33	2.70e-04	71	61	3	36305789
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH8 DNAH11	2.72e-04	14	61	2	9373155
Pubmed	Identification of protein arginine methyltransferase 2 as a coactivator for estrogen receptor alpha.	SCARB1 PRMT2	2.72e-04	14	61	2	12039952
Interaction	PRDM16 interactions	TECR TIMM50 RBM14 USP7 RUNX1T1 PLK4	2.46e-05	195	60	6	int:PRDM16
Interaction	RHOF interactions	DLG5 VPS52 CSNK1E WWP2 SCARB1 EFR3B ITGA6 TTC9C SLC4A2 EFR3A	2.69e-05	673	60	10	int:RHOF
Interaction	LDLRAD4 interactions	CSNK1D CSNK1E WWP2 DHX38	2.86e-05	59	60	4	int:LDLRAD4
Interaction	RAB35 interactions	DLG5 TECR SCARB1 TIMM50 RBM14 EFR3B ITGA6 SLC4A2 EFR3A	4.63e-05	573	60	9	int:RAB35
Interaction	LAPTM5 interactions	WWP2 TECR USP7 DISP1	4.73e-05	67	60	4	int:LAPTM5
Interaction	DBNDD1 interactions	CSNK1D CSNK1E	5.21e-05	4	60	2	int:DBNDD1
Interaction	FAM199X interactions	KCNE3 CSNK1D CSNK1E	5.51e-05	25	60	3	int:FAM199X
Interaction	CA2 interactions	CSNK1E USP7 SLC4A3 SLC4A2	6.99e-05	74	60	4	int:CA2
GeneFamily	DEAH-box helicases	DHX38 DHX33	6.19e-04	16	42	2	500
GeneFamily	Dyneins, axonemal	DNAH8 DNAH11	7.01e-04	17	42	2	536
CoexpressionAtlas	DevelopingKidney_e11.5_ureteric bud_emap-3844_k-means-cluster#1_top-relative-expression-ranked_1000	PTPN2 WWP2 TECR RBM14 USP7 EFR3B PAX3 TSEN2	7.85e-07	261	61	8	gudmap_developingKidney_e11.5_ureteric bud_1000_k1
CoexpressionAtlas	DevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#3_top-relative-expression-ranked_1000	OGFRL1 PTPN2 CSNK1E RBM14 USP7 EFR3B PAX3 TSEN2	1.17e-05	376	61	8	gudmap_developingKidney_e11.5_metaneph mesench_1000_k3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPTLC3 DLG5 ITGA6 KCNG3 DNAH11	1.73e-06	146	61	5	ec1f793409d1a81c0f9323eb3c82ffe01dae0e44
ToppCell	PND07-Immune-Immune_Myeloid-Granulocytic-Mast-Mast_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPN2 FOXRED2 KCNE3 INPP5D EMILIN2	2.71e-06	160	61	5	5d22c86deead516444349d495998e04586be4396
ToppCell	PND07-Immune-Immune_Myeloid-Granulocytic-Mast\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPN2 FOXRED2 KCNE3 INPP5D EMILIN2	2.71e-06	160	61	5	ca212634cf1875238071d1800ecdf34979a553fb
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TECR ITGA6 PRMT2 DLEC1 CUBN	2.79e-06	161	61	5	5fba13f0aa5002f7eefe219e2c6a07e163f1a50d
Disease	whole-brain volume	CUBN DNAH11	3.92e-05	5	59	2	EFO_0005089
Disease	syndromic X-linked intellectual disability Najm type (implicated_via_orthology)	CSNK1D CSNK1E	8.20e-05	7	59	2	DOID:0060807 (implicated_via_orthology)
Disease	phospholipids:total lipids ratio	PSD SCARB1 NCAN DHX38 MYRF	9.20e-05	227	59	5	EFO_0020946
Disease	fish oil supplement exposure measurement, triglyceride measurement	GJB6 NCAN	1.75e-04	10	59	2	EFO_0004530, EFO_0600007
Disease	linoleoyl-arachidonoyl-glycerol (18:2/20:4) [2] measurement	NCAN MYRF	2.56e-04	12	59	2	EFO_0800500
Disease	level of Phosphatidylcholine (O-18:1_20:4) in blood serum	SCARB1 MYRF	4.06e-04	15	59	2	OBA_2045131
Disease	anemia (implicated_via_orthology)	SLC4A3 SLC4A2	4.06e-04	15	59	2	DOID:2355 (implicated_via_orthology)
Disease	sensory peripheral neuropathy, remission	DLEC1 RUNX1T1	9.68e-04	23	59	2	EFO_0009785, MONDO_0002321
Disease	triacylglycerol 56:7 measurement	NCAN MYRF	1.54e-03	29	59	2	EFO_0010434
Disease	Severe Congenital Microcephaly	TSEN2 PLK4	1.76e-03	31	59	2	C3853041
Disease	level of Phosphatidylcholine (18:0_20:4) in blood serum	TTC9C MYRF	1.76e-03	31	59	2	OBA_2045094
Disease	very low density lipoprotein cholesterol measurement	SCARB1 NCAN DHX38 DNAH11	1.83e-03	260	59	4	EFO_0008317
Disease	prostate cancer (implicated_via_orthology)	CHD2 PAX3	1.99e-03	33	59	2	DOID:10283 (implicated_via_orthology)
Disease	Microlissencephaly	TSEN2 PLK4	1.99e-03	33	59	2	C1956147

Protein segments in the cluster

Peptide	Gene	Start	Entry
RRYPHYLSDFRDALD	SLC4A2	691	P04920
KPSRSYSERDFEFHR	SLC4A3	61	P48751
AHYARPRAVYAVEAS	PRMT2	156	P55345
PYSFARYRTTEESKR	ALKBH8	81	Q96BT7
AKQAEFRERFRHYAP	DNAH11	1256	Q96DT5
SSHKLRLYERDDYRG	CRYGA	86	P11844
ARARFESKVPSFYYR	ADAP1	81	O75689
RSSHPFERYDAEYKK	DISP1	756	Q96F81
SFEKRPRASFHTIRY	EAF1	21	Q96JC9
EDTPSYHRRYDFFVS	EFR3A	131	Q14156
RRLPDAHSDYARYSG	RBM14	636	Q96PK6
NRYRDVSPYDHSRVK	PTPN2	46	P17706
YHELKFRSARYSRSL	KCNG3	416	Q8TAE7
TAKPKRSFYAARDLY	OGFRL1	86	Q5TC84
DRAPERYTSRFYLKF	KCTD16	216	Q68DU8
YRDSYRHPSHRDLRD	RUNX1T1	311	Q06455
RSRKVDKRSDPYHVY	KCNE3	81	Q9Y6H6
EDHERERFYIYRKPS	KIAA1109	3736	Q2LD37
ERFYIYRKPSHTSRK	KIAA1109	3741	Q2LD37
DTPSYHRSYDFFVSR	EFR3B	131	Q9Y2G0
SYFQRYRRRAHVTPK	DNAH8	3026	Q96JB1
YRRRAHVTPKSYLSF	DNAH8	3031	Q96JB1
RSLRFDDKPDYSYLR	CSNK1D	256	P48730
FSRLSPEYYDLARAH	GNLY	21	P22749
FDKRPYHRLNPDYER	DLG5	176	Q8TDM6
FKRSRYDDSVPRYHA	ITGA6	1081	P23229
FRHYSRAYFPDARDM	FOXRED2	111	Q8IWF2
RAFERTHYPDIYTRE	PAX3	236	P23760
PASYAYRERREKLHV	OVOL3	176	O00110
FHADYARRPSAFRLT	CUBN	3606	O60494
GYLYRRDTDHTRKRF	GUCA1ANB	101	X6R8D5
RKRPYDQYSSDRDHR	CHD2	1696	O14647
AYYRHETTRKFRRGE	GJB6	96	O95452
YEAAPEYFRRKLRTA	DHX33	691	Q9H6R0
HTAGYRREFLEYHRP	EMILIN2	981	Q9BXX0
YSEAFHYSFAARPRR	DLEC1	51	Q9Y238
FRRKSFYSSHYARER	PPHLN1	106	Q8NEY8
YARERSPYKRDNTFF	PPHLN1	116	Q8NEY8
FHAPKRKRRVYETYE	TSEN2	6	Q8NCE0
RASDYSKRPHVFYLR	PSD	826	A5PKW4
VFHYRSARDRYALTF	NCAN	161	O14594
YDDSAFVEPRYHVRR	POTEJ	86	P0CG39
APTYRFERLTRDKYA	INPP5D	641	Q92835
PYVYREFRHKSNITF	SCARB1	91	Q8WTV0
SSFFYRHKDSRYLTP	SLC41A3	241	Q96GZ6
YSRHKKSARPELYDE	SPTLC3	531	Q9NUV7
ERPHSRYLRRAYSSD	PLK4	366	O00444
PHYITRRYAEFSSAL	VPS52	506	Q8N1B4
SKAFPFYSSYLRHER	ZNF823	226	P16415
HGFISYRLFRDATRY	TIMM50	211	Q3ZCQ8
DPRGRFYYVDHNTRT	WWP2	341	O00308
PARYRRAVSYDSKEY	WDFY3	2426	Q8IZQ1
SKYAADRNHYRRYPR	YBX1	136	P67809
ASRHDPSRPYAEQYR	TBC1D8	841	O95759
HRSYLKEFRDYPPLR	TECR	286	Q9NZ01
FHNPLAYSSEDYVRR	DHX38	336	Q92620
EGKYRDAVSRYHRAL	TTC9C	21	Q8N5M4
FDRPSYDRKSDRPVY	YLPM1	1761	P49750
SKAFPDYSSYVRHER	ZNF442	271	Q9H7R0
SKAFPFYSSYRRHER	ZNF563	231	Q8TA94
HEFTEYTRRYREASP	ZNF711	446	Q9Y462
HFNKAPKRSRYTYLE	USP7	1081	Q93009
RTPYAASRDFDVKYV	MST1R	31	Q04912
HFPRSYELTRKDRLY	TTLL5	121	Q6EMB2
RSLRFDDKPDYSYLR	CSNK1E	256	P49674
RLVHYRYKPEFAASA	MYRF	611	Q9Y2G1