Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	presynaptic active zone membrane	CACNA1A GRIN2D P2RY4	3.00e-04	78	35	3	GO:0048787
Domain	GSK3-bd	FRAT1 FRAT2	3.03e-06	2	33	2	IPR008014
Domain	GSK-3_bind	FRAT1 FRAT2	3.03e-06	2	33	2	PF05350
Domain	CUB	CSMD1 PDGFD	3.38e-03	49	33	2	PF00431
Domain	CUB	CSMD1 PDGFD	3.52e-03	50	33	2	SM00042
Domain	-	CSMD1 PDGFD	3.80e-03	52	33	2	2.60.120.290
Domain	CUB	CSMD1 PDGFD	3.94e-03	53	33	2	PS01180
Domain	CUB_dom	CSMD1 PDGFD	4.55e-03	57	33	2	IPR000859
Domain	-	ARTN PDGFD	6.23e-03	67	33	2	2.10.90.10
Domain	Cystine-knot_cytokine	ARTN PDGFD	6.23e-03	67	33	2	IPR029034
Pubmed	Characterization and functional analysis of the murine Frat2 gene.	FRAT1 FRAT2	3.48e-06	3	38	2	15073180
Pubmed	Frat is a phosphatidylinositol 3-kinase/Akt-regulated determinant of glycogen synthase kinase 3β subcellular localization in pluripotent cells.	FRAT1 FRAT2	3.48e-06	3	38	2	22064483
Pubmed	Characterization and tissue-specific expression of human GSK-3-binding proteins FRAT1 and FRAT2.	FRAT1 FRAT2	3.48e-06	3	38	2	12095675
Pubmed	The miR-3648/FRAT1-FRAT2/c-Myc negative feedback loop modulates the metastasis and invasion of gastric cancer cells.	FRAT1 FRAT2	6.96e-06	4	38	2	36153370
Pubmed	The structure of phosphorylated GSK-3beta complexed with a peptide, FRATtide, that inhibits beta-catenin phosphorylation.	FRAT1 FRAT2	6.96e-06	4	38	2	11738041
Pubmed	Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways.	FRAT1 FRAT2	1.16e-05	5	38	2	19802005
Pubmed	Frat is dispensable for canonical Wnt signaling in mammals.	FRAT1 FRAT2	1.74e-05	6	38	2	15681612
Pubmed	Nine new human Rhodopsin family G-protein coupled receptors: identification, sequence characterisation and evolutionary relationship.	GPR152 GPR150	4.16e-05	9	38	2	15777626
Pubmed	Differential RET signaling pathways drive development of the enteric lymphoid and nervous systems.	ARTN GFRA4	9.00e-05	13	38	2	22855506
Pubmed	Genome-wide CRISPR Screen to Identify Genes that Suppress Transformation in the Presence of Endogenous KrasG12D.	ARTN NFKBIL1	2.90e-04	23	38	2	31748650
Pubmed	Genome-wide association study of selenium concentrations.	CSMD1 PDGFD	6.76e-04	35	38	2	25343990
Pubmed	Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.	CSMD1 PDGFD	8.40e-04	39	38	2	21347282
Cytoband	10q24.1	FRAT1 FRAT2	1.53e-04	22	38	2	10q24.1
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	CACNA1A REX1BD PGLYRP2 PTGER1	4.17e-03	797	38	4	chr19p13
Cytoband	Ensembl 112 genes in cytogenetic band chr20p13	GFRA4 TMEM239	4.70e-03	123	38	2	chr20p13
Cytoband	Ensembl 112 genes in cytogenetic band chr2q35	ASIC4 CYP27A1	5.15e-03	129	38	2	chr2q35
GeneFamily	G protein-coupled receptors, Class A orphans	GPR152 GPR150	3.66e-03	78	21	2	262
Coexpression	ZAK_PBMC_MRKAD5_HIV_1_GAG_POL_NEF_AGE_20_50YO_CORRELATED_WITH_CD8_T_CELL_RESPONSE_3DY_NEGATIVE	GPR152 ARTN CLCNKA PTGER1	1.28e-05	99	38	4	M40881
Disease	tea consumption measurement	ARTN CSMD1 PLEKHH3	5.24e-04	129	36	3	EFO_0010091
Disease	myopathy (implicated_via_orthology)	FHL1 CLCNKA	1.58e-03	48	36	2	DOID:423 (implicated_via_orthology)
Disease	cannabis dependence measurement	PI4K2B CSMD1	1.58e-03	48	36	2	EFO_0008457
Disease	interferon gamma measurement	KRBA1 PDGFD	1.78e-03	51	36	2	EFO_0008165

Protein segments in the cluster

Peptide	Gene	Start	Entry
RACRHGGARWPASGP	CACNA1A	2381	O00555
LGGGRRVWSAPLPRC	CSMD1	1086	Q96PZ7
RRHRRPGGFPLAWGS	BBC3	101	Q96PG8
GWCAGPRRRHAPGTE	ASB16-AS1	121	Q495Z4
TLPRGPRWAHGPGHR	KRBA1	856	A5PL33
LHRWGGCGPHCRLRG	KMT5C	356	Q86Y97
PAGHLPGGRTARWCS	ARTN	61	Q5T4W7
IRGRWCGHKEVPPRI	PDGFD	126	Q9GZP0
GPDSRRRWGAHGPRS	PTGER1	246	P34995
AIHPRCRWGAAPYRG	PGLYRP2	381	Q96PD5
GHRPVRLPLWVCAGV	GPR152	141	Q8TDT2
TRPCRGPWRSCGRVH	GOLGA2P5	86	Q9HBQ8
RACGPGPHGLRRTLW	ASIC4	56	Q96FT7
PREEHPRGAGRGSLW	NFKBIL1	281	Q9UBC1
RAVGHHGDGPRPWLR	KIF19	856	Q2TAC6
PRIAWAHPRRGAPGS	PI4K2B	31	Q8TCG2
GICHPLRALRWGRPR	P2RY4	136	P51582
RGRHPGGERTCPSWV	FHL1	266	Q13642
RGWGRGLSPAHRPPA	GFRA4	141	Q9GZZ7
ATGLFLGRRCPPWRG	COMTD1	26	Q86VU5
WALRGAGRGLCPHGA	CYP27A1	11	Q02318
PTAGPRPRGRLHHWL	IFNL1	136	Q8IU54
RRCWGPPLAHGARRG	MTFMT	6	Q96DP5
GILNVHPSCLPRWRG	MTFMT	141	Q96DP5
PQPLSGPCRRGWLRG	FRAT1	161	Q92837
GPSALPGPCRRGWLR	FRAT2	136	O75474
PDSGWRLCLRLHGPL	PLEKHH3	486	Q7Z736
RLRAYRPPGPGGHWC	SSPOP	3971	A2VEC9
MLLGSLWGRCHPGRC	TMEM238L	1	A6NJY4
PAARAWPGERRCHGI	GPR150	206	Q8NGU9
ARRRAWHGARLPGSP	PRR34	91	Q9NV39
WHGARLPGSPARAGR	PRR34	96	Q9NV39
PGCPRCRARGPGWAR	RNF169	101	Q8NCN4
LWGPCPHIRRAIQGG	CLCNKA	21	P51800
FRGLHWGLRRLPTPE	TLCD2	16	A6NGC4
AWGRGLRVPTCRRGH	REX1BD	71	Q96EN9
DPRPHLGGSCSLRRW	TTLL10	571	Q6ZVT0
WICLPGRPGRCRKQH	TMEM239	6	Q8WW34
GRPGLPQGRHLCWLL	JTB	6	O76095
HRHRRAAGGWDLPPP	GRIN2D	1251	O15399