Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	alpha-glucoside transmembrane transporter activity	SLC5A1 SLC5A2	3.76e-05	2	123	2	GO:0015151
GeneOntologyMolecularFunction	glucoside transmembrane transporter activity	SLC5A1 SLC5A2	1.12e-04	3	123	2	GO:0042947
GeneOntologyMolecularFunction	protein O-acetylglucosaminyltransferase activity	OGT POMGNT2	1.12e-04	3	123	2	GO:0097363
GeneOntologyMolecularFunction	rRNA (cytosine-C5-)-methyltransferase activity	NSUN5 NSUN5P2	2.24e-04	4	123	2	GO:0009383
Domain	RIBOSOMAL_S4E	RPS4Y2 RPS4X RPS4Y1	2.79e-07	3	123	3	PS00528
Domain	Ribosomal_S4e_central_region	RPS4Y2 RPS4X RPS4Y1	2.79e-07	3	123	3	IPR013845
Domain	Ribosomal_S4e_N	RPS4Y2 RPS4X RPS4Y1	2.79e-07	3	123	3	IPR013843
Domain	Ribosomal_S4e_central	RPS4Y2 RPS4X RPS4Y1	2.79e-07	3	123	3	PD002667
Domain	40S_S4_C	RPS4Y2 RPS4X RPS4Y1	2.79e-07	3	123	3	PF16121
Domain	40S_S4_C	RPS4Y2 RPS4X RPS4Y1	2.79e-07	3	123	3	IPR032277
Domain	Ribosomal_S4e_N_CS	RPS4Y2 RPS4X RPS4Y1	2.79e-07	3	123	3	IPR018199
Domain	RS4NT	RPS4Y2 RPS4X RPS4Y1	2.79e-07	3	123	3	PF08071
Domain	Ribosomal_S4e	RPS4Y2 RPS4X RPS4Y1	2.79e-07	3	123	3	IPR000876
Domain	Ribosomal_S4e	RPS4Y2 RPS4X RPS4Y1	2.79e-07	3	123	3	PF00900
Domain	S4	RPS4Y2 RPS4X RPS4Y1	2.76e-06	5	123	3	SM00363
Domain	S4	RPS4Y2 RPS4X RPS4Y1	2.76e-06	5	123	3	PS50889
Domain	S4_RNA-bd	RPS4Y2 RPS4X RPS4Y1	5.49e-06	6	123	3	IPR002942
Domain	Cyt_c_oxidase_su6a	COX6A1 COX6A2	4.30e-05	2	123	2	PD006036
Domain	-	COX6A1 COX6A2	4.30e-05	2	123	2	4.10.95.10
Domain	Cyt_c_oxidase_su6a_CS	COX6A1 COX6A2	4.30e-05	2	123	2	IPR018507
Domain	Cyt_c_oxidase_su6a	COX6A1 COX6A2	4.30e-05	2	123	2	IPR001349
Domain	COX6A	COX6A1 COX6A2	4.30e-05	2	123	2	PS01329
Domain	COX6A	COX6A1 COX6A2	4.30e-05	2	123	2	PF02046
Domain	KOW	RPS4Y2 RPS4X RPS4Y1	4.43e-05	11	123	3	IPR005824
Domain	KOW	RPS4Y2 RPS4X RPS4Y1	4.43e-05	11	123	3	PF00467
Domain	NHR2	RUNX1T1 CBFA2T3	1.29e-04	3	123	2	PF08788
Domain	CBFA2T1/2/3	RUNX1T1 CBFA2T3	1.29e-04	3	123	2	IPR013289
Domain	NHR2	RUNX1T1 CBFA2T3	1.29e-04	3	123	2	IPR014896
Domain	RetinoicA-induced_16-like	FHIP2A FHIP2B	2.56e-04	4	123	2	IPR019384
Domain	RAI16-like	FHIP2A FHIP2B	2.56e-04	4	123	2	PF10257
Domain	S4	RPS4X RPS4Y1	2.56e-04	4	123	2	PF01479
Domain	TAFH	RUNX1T1 CBFA2T3	4.25e-04	5	123	2	SM00549
Domain	TAFH_NHR1	RUNX1T1 CBFA2T3	4.25e-04	5	123	2	IPR003894
Domain	PAN_AP	HGF MST1L	4.25e-04	5	123	2	SM00473
Domain	TAFH	RUNX1T1 CBFA2T3	4.25e-04	5	123	2	PS51119
Domain	TAFH	RUNX1T1 CBFA2T3	4.25e-04	5	123	2	PF07531
Domain	PH	PRKD2 RASGRF1 MYO10 PLEKHH1 AFAP1L2 FGD1 PLD2	8.10e-04	229	123	7	PF00169
Domain	Pan_app	HGF MST1L	8.84e-04	7	123	2	IPR003609
Domain	PAN	HGF MST1L	8.84e-04	7	123	2	PS50948
Domain	PAN_1	HGF MST1L	8.84e-04	7	123	2	PF00024
Domain	MeTrfase_RsmB/NOP2	NSUN5 NSUN5P2	1.17e-03	8	123	2	IPR001678
Domain	Na/solute_symporter_CS	SLC5A1 SLC5A2	1.17e-03	8	123	2	IPR018212
Domain	Methyltr_RsmB-F	NSUN5 NSUN5P2	1.17e-03	8	123	2	PF01189
Domain	IQ	MYO1D RASGRF1 MYO10 ASPM	1.24e-03	71	123	4	PF00612
Domain	MYTH4	MYO10 PLEKHH1	1.50e-03	9	123	2	PS51016
Domain	MyTH4	MYO10 PLEKHH1	1.50e-03	9	123	2	SM00139
Domain	MyTH4_dom	MYO10 PLEKHH1	1.50e-03	9	123	2	IPR000857
Domain	MyTH4	MYO10 PLEKHH1	1.50e-03	9	123	2	PF00784
Domain	PTrfase/Anion_transptr	SLC4A3 SLC4A11	1.87e-03	10	123	2	IPR016152
Domain	HCO3_transpt_euk	SLC4A3 SLC4A11	1.87e-03	10	123	2	IPR003020
Domain	HCO3_cotransp	SLC4A3 SLC4A11	1.87e-03	10	123	2	PF00955
Domain	HCO3_transpt_C	SLC4A3 SLC4A11	1.87e-03	10	123	2	IPR011531
Domain	IQ	MYO1D RASGRF1 MYO10 ASPM	2.02e-03	81	123	4	SM00015
Domain	HlyIII	PAQR5 PAQR7	2.28e-03	11	123	2	PF03006
Domain	NA_SOLUT_SYMP_1	SLC5A1 SLC5A2	2.28e-03	11	123	2	PS00456
Domain	AdipoR/HlyIII-related	PAQR5 PAQR7	2.28e-03	11	123	2	IPR004254
Domain	PH	PRKD2 RASGRF1 MYO10 PLEKHH1 AFAP1L2 FGD1 PLD2	2.46e-03	278	123	7	SM00233
Domain	PH_DOMAIN	PRKD2 RASGRF1 MYO10 PLEKHH1 AFAP1L2 FGD1 PLD2	2.51e-03	279	123	7	PS50003
Domain	PH_domain	PRKD2 RASGRF1 MYO10 PLEKHH1 AFAP1L2 FGD1 PLD2	2.56e-03	280	123	7	IPR001849
Domain	SSF	SLC5A1 SLC5A2	2.72e-03	12	123	2	PF00474
Domain	NA_SOLUT_SYMP_2	SLC5A1 SLC5A2	2.72e-03	12	123	2	PS00457
Domain	Na/solute_symporter	SLC5A1 SLC5A2	2.72e-03	12	123	2	IPR001734
Domain	NA_SOLUT_SYMP_3	SLC5A1 SLC5A2	2.72e-03	12	123	2	PS50283
Domain	IQ_motif_EF-hand-BS	MYO1D RASGRF1 MYO10 ASPM	2.96e-03	90	123	4	IPR000048
Domain	IQ	MYO1D RASGRF1 MYO10 ASPM	3.33e-03	93	123	4	PS50096
Domain	Kringle_CS	HGF MST1L	5.48e-03	17	123	2	IPR018056
Domain	KRINGLE_1	HGF MST1L	5.48e-03	17	123	2	PS00021
Domain	KR	HGF MST1L	5.48e-03	17	123	2	SM00130
Domain	Kringle	HGF MST1L	5.48e-03	17	123	2	IPR000001
Domain	KRINGLE_2	HGF MST1L	5.48e-03	17	123	2	PS50070
Domain	Kringle	HGF MST1L	5.48e-03	17	123	2	PF00051
Pubmed	Physical mapping of 2000 kb of the mouse X chromosome in the vicinity of the Xist locus.	RPS4Y2 RPS4X RPS4Y1 PHKA1	1.07e-08	8	124	4	8468051
Pubmed	Cloning and localization of the murine Xpct gene: evidence for complex rearrangements during the evolution of the region around the Xist gene.	RPS4Y2 RPS4X RPS4Y1 PHKA1	1.91e-08	9	124	4	9545634
Pubmed	Inactivation of the Rps4 gene on the mouse X chromosome.	RPS4Y2 RPS4X RPS4Y1	4.42e-08	3	124	3	1783379
Pubmed	Homologous ribosomal protein genes on the human X and Y chromosomes: escape from X inactivation and possible implications for Turner syndrome.	RPS4Y2 RPS4X RPS4Y1	4.42e-08	3	124	3	2124517
Pubmed	Expression level of Rps4 mRNA in 39,X mice and 40,XX mice.	RPS4Y2 RPS4X RPS4Y1	4.42e-08	3	124	3	8187552
Pubmed	Relationship between the monosomy X phenotype and Y-linked ribosomal protein S4 (Rps4) in several species of mammals: a molecular evolutionary analysis of Rps4 homologs.	RPS4Y2 RPS4X RPS4Y1	4.42e-08	3	124	3	8808278
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PRKD2 FRAS1 LPAR5 MYO10 COX6A1 ADGRB2 LAMA5 NPHP4 DUS1L SLC52A3 NCOR2 PWWP2B POMGNT2 ZNRF3 BTBD7 PCNX1 GGA1 GAREM1	8.15e-08	1105	124	18	35748872
Pubmed	Rps4 maps near the inactivation center on the mouse X chromosome.	RPS4Y2 RPS4X RPS4Y1 PHKA1	1.07e-07	13	124	4	1740345
Pubmed	XIST and the mapping of the X chromosome inactivation centre.	RPS4Y2 RPS4X RPS4Y1 PHKA1	1.07e-07	13	124	4	1772416
Pubmed	Analysis of genes from inner ear developmental-stage cDNA subtraction reveals molecular regionalization of the otic capsule.	RPS4Y2 RPS4X RPS4Y1 ST7L CLU	1.58e-07	35	124	5	15031101
Pubmed	Structure and function of ribosomal protein S4 genes on the human and mouse sex chromosomes.	RPS4Y2 RPS4X RPS4Y1	1.76e-07	4	124	3	8139551
Pubmed	Use of a reverse transcriptase-polymerase chain reaction assay to analyze allele-specific expression in individual hippocampal neurons.	RPS4Y2 RPS4X RPS4Y1	4.40e-07	5	124	3	9562962
Pubmed	Maintenance of X inactivation of the Rps4, Zfx, and Ube1 genes in a mouse in vitro system.	RPS4Y2 RPS4X RPS4Y1	4.40e-07	5	124	3	7681608
Pubmed	An evaluation of the inactive mouse X chromosome in somatic cell hybrids.	RPS4Y2 RPS4X RPS4Y1	1.53e-06	7	124	3	8460399
Pubmed	Embryonic growth and the evolution of the mammalian Y chromosome. II. Suppression of selfish Y-linked growth factors may explain escape from X-inactivation and rapid evolution of Sry.	RPS4Y2 RPS4X RPS4Y1	1.53e-06	7	124	3	7928394
Pubmed	The transcriptional corepressor MTG16a contains a novel nucleolar targeting sequence deranged in t (16; 21)-positive myeloid malignancies.	RUNX1T1 CBFA2T3 NCOR2	1.53e-06	7	124	3	12242670
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	LPAR5 MYO10 NADK2 HMX3 COX6A1 SLC5A2 SLC52A3 PTPN2 ARID1B GTF2H2 ASPM UNK MST1L TP53RK ARMH3 SEC23A	9.24e-06	1242	124	16	30973865
Pubmed	Cognitive deficits in mice lacking Nsun5, a cytosine-5 RNA methyltransferase, with impairment of oligodendrocyte precursor cells.	NSUN5 NSUN5P2	1.26e-05	2	124	2	30485550
Pubmed	Molecular evolution of cytochrome c oxidase: rate variation among subunit VIa isoforms.	COX6A1 COX6A2	1.26e-05	2	124	2	9190060
Pubmed	Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia.	SLC5A1 SLC5A2	1.26e-05	2	124	2	24226519
Pubmed	FAM160B1 deficit associated with microcephaly, severe intellectual disability, ataxia, behavioral abnormalities and speech problems.	FHIP2A FHIP2B	1.26e-05	2	124	2	31353455
Pubmed	Cloning, sequence analysis, and expression of a mouse cDNA encoding cytochrome c oxidase subunit VIa liver isoform.	COX6A1 COX6A2	1.26e-05	2	124	2	7873616
Pubmed	Membrane progestin receptors alpha and gamma in renal epithelium.	PAQR5 PAQR7	1.26e-05	2	124	2	18722485
Pubmed	Thioglycosides as inhibitors of hSGLT1 and hSGLT2: potential therapeutic agents for the control of hyperglycemia in diabetes.	SLC5A1 SLC5A2	1.26e-05	2	124	2	17505558
Pubmed	Mice with NOP2/sun RNA methyltransferase 5 deficiency die before reaching puberty due to fatal kidney damage.	NSUN5 NSUN5P2	1.26e-05	2	124	2	38712768
Pubmed	Tissue distribution of cytochrome c oxidase isoforms in mammals. Characterization with monoclonal and polyclonal antibodies.	COX6A1 COX6A2	1.26e-05	2	124	2	8241294
Pubmed	Glycaemia and body weight are regulated by sodium-glucose cotransporter 1 (SGLT1) expression via O-GlcNAcylation in the intestine.	OGT SLC5A1	1.26e-05	2	124	2	35189429
Pubmed	RNA-methyltransferase Nsun5 controls the maternal-to-zygotic transition by regulating maternal mRNA stability.	NSUN5 NSUN5P2	1.26e-05	2	124	2	36495115
Pubmed	Renal SGLT mRNA expression in human health and disease: a study in two cohorts.	SLC5A1 SLC5A2	1.26e-05	2	124	2	31545924
Pubmed	Molecular determinants of renal glucose reabsorption. Focus on "Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2".	SLC5A1 SLC5A2	1.26e-05	2	124	2	21048164
Pubmed	Differential expression of genes specifying two isoforms of subunit VIa of human cytochrome c oxidase.	COX6A1 COX6A2	1.26e-05	2	124	2	1327966
Pubmed	Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2.	SLC5A1 SLC5A2	1.26e-05	2	124	2	20980548
Pubmed	Sodium-glucose co-transporter (SGLT)2 and SGLT1 renal expression in patients with type 2 diabetes.	SLC5A1 SLC5A2	1.26e-05	2	124	2	28419670
Pubmed	Loss of the ribosomal RNA methyltransferase NSUN5 impairs global protein synthesis and normal growth.	NSUN5 NSUN5P2	1.26e-05	2	124	2	31722427
Pubmed	Turkey cytochrome c oxidase contains subunit VIa of the liver type associated with low efficiency of energy transduction.	COX6A1 COX6A2	1.26e-05	2	124	2	10727950
Pubmed	Agenesis and Hypomyelination of Corpus Callosum in Mice Lacking Nsun5, an RNA Methyltransferase.	NSUN5 NSUN5P2	1.26e-05	2	124	2	31174389
Pubmed	SWI/SNF regulates a transcriptional program that induces senescence to prevent liver cancer.	ENTPD7 ARID1B	1.26e-05	2	124	2	27737960
Pubmed	Deletion of an AML1-ETO C-terminal NcoR/SMRT-interacting region strongly induces leukemia development.	RUNX1T1 NCOR2	1.26e-05	2	124	2	15569932
Pubmed	ETO-2, a new member of the ETO-family of nuclear proteins.	RUNX1T1 CBFA2T3	1.26e-05	2	124	2	10022820
Pubmed	NSUN5 is essential for proper cell proliferation and differentiation of mouse preimplantation embryos.	NSUN5 NSUN5P2	1.26e-05	2	124	2	38670153
Pubmed	Functional equivalence of human X- and Y-encoded isoforms of ribosomal protein S4 consistent with a role in Turner syndrome.	RPS4X RPS4Y1	1.26e-05	2	124	2	8358435
Pubmed	Expression of membrane progesterone receptors (mPR/PAQR) in ovarian cancer cells: implications for progesterone-induced signaling events.	PAQR5 PAQR7	3.77e-05	3	124	2	21761364
Pubmed	CNS erythroblastic sarcoma: a potential emerging pediatric tumor type characterized by NFIA::RUNX1T1/3 fusions.	RUNX1T1 CBFA2T3	3.77e-05	3	124	2	38243303
Pubmed	Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes.	PAQR5 PAQR7	3.77e-05	3	124	2	12574519
Pubmed	Sodium-glucose co-transporter (SGLT) and glucose transporter (GLUT) expression in the kidney of type 2 diabetic subjects.	SLC5A1 SLC5A2	3.77e-05	3	124	2	28477418
Pubmed	Improved glycemic control in mice lacking Sglt1 and Sglt2.	SLC5A1 SLC5A2	3.77e-05	3	124	2	23149623
Pubmed	Antibodies to a renal Na+/glucose cotransport system localize to the apical plasma membrane domain of polar mouse embryo blastomeres.	SLC5A1 SLC5A2	3.77e-05	3	124	2	1702069
Pubmed	CBFA2T1, a gene rearranged in human leukemia, is a member of a multigene family.	RUNX1T1 CBFA2T3	3.77e-05	3	124	2	9790752
Pubmed	Primer-BLAST: a tool to design target-specific primers for polymerase chain reaction.	RPS4Y2 RPS4Y1	3.77e-05	3	124	2	22708584
Pubmed	O-GlcNAc modification affects the ATM-mediated DNA damage response.	OGT PTPA	3.77e-05	3	124	2	22759405
Pubmed	Oligomerization of ETO is obligatory for corepressor interaction.	RUNX1T1 NCOR2	3.77e-05	3	124	2	11113190
Pubmed	Differential regulation of mouse kidney sodium-dependent transporters mRNA by cadmium.	SLC5A1 SLC5A2	3.77e-05	3	124	2	11749115
Pubmed	The gene encoding the erythrocyte membrane skeleton protein dematin (Epb4.9) maps to mouse chromosome 14.	CLU DMTN	3.77e-05	3	124	2	7607697
Pubmed	Physiology of renal glucose handling via SGLT1, SGLT2 and GLUT2.	SLC5A1 SLC5A2	3.77e-05	3	124	2	30132032
Pubmed	NSUN5 Facilitates Viral RNA Recognition by RIG-I Receptor.	NSUN5 NSUN5P2	3.77e-05	3	124	2	33177158
Pubmed	Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor.	PAQR5 PAQR7	3.77e-05	3	124	2	12601167
Pubmed	Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome.	RPS4Y2 RPS4X RPS4Y1	4.82e-05	20	124	3	16635246
Pubmed	BAP1 maintains chromosome stability by stabilizing DIDO1 in renal cell carcinoma.	PRKD2 OGT NSUN5	4.82e-05	20	124	3	32509391
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SHANK1 RPS4Y2 OGT HYOU1 MYO1D DOCK8 RPS4X RPS4Y1 PPFIA4 TWF2 NT5DC3 STRIP1 CLU EXOC1 SEC23A DMTN	5.13e-05	1431	124	16	37142655
Pubmed	Aberrant recruitment of the nuclear receptor corepressor-histone deacetylase complex by the acute myeloid leukemia fusion partner ETO.	RUNX1T1 NCOR2	7.53e-05	4	124	2	9819405
Pubmed	Expression of glucose transporters in duodenal mucosa of patients with type 1 diabetes.	SLC5A1 SLC5A2	7.53e-05	4	124	2	32617672
Pubmed	Characterization of two novel genes, WBSCR20 and WBSCR22, deleted in Williams-Beuren syndrome.	NSUN5 NSUN5P2	7.53e-05	4	124	2	11978965
Pubmed	Assignment of COX6A1 to 6p21 and a pseudogene (COX6A1P) to 1p31.1 by in situ hybridization and somatic cell hybrids.	COX6A1 COX6A2	7.53e-05	4	124	2	9284905
Pubmed	Mouse mitotic spindle checkpoint Bub3 gene maps to the distal region of chromosome 7 by interspecific backcross analysis.	HMX3 COX6A2	7.53e-05	4	124	2	10640819
Pubmed	ZNF652, a novel zinc finger protein, interacts with the putative breast tumor suppressor CBFA2T3 to repress transcription.	RUNX1T1 CBFA2T3	7.53e-05	4	124	2	16966434
Pubmed	GRP78 regulates clusterin stability, retrotranslocation and mitochondrial localization under ER stress in prostate cancer.	HYOU1 CLU	7.53e-05	4	124	2	22689054
Pubmed	The Flt3 internal tandem duplication mutant inhibits the function of transcriptional repressors by blocking interactions with SMRT.	RUNX1T1 NCOR2	7.53e-05	4	124	2	14982881
Pubmed	Interactions between the leukaemia-associated ETO homologues of nuclear repressor proteins.	RUNX1T1 CBFA2T3	7.53e-05	4	124	2	14703694
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FRAS1 MYO10 FHIP2A CSMD3 STRIP1 NEDD4 PLEKHH1 BTBD7	1.11e-04	407	124	8	12693553
Pubmed	Regional expression of MTG genes in the developing mouse central nervous system.	RUNX1T1 CBFA2T3	1.25e-04	5	124	2	19618476
Pubmed	Heterologous expression of human mPRalpha, mPRbeta and mPRgamma in yeast confirms their ability to function as membrane progesterone receptors.	PAQR5 PAQR7	1.25e-04	5	124	2	18603275
Pubmed	Transcriptional repression by leukaemia-associated ETO family members can be independent of oligomerization and coexpressed hSIN3B and N-CoR.	RUNX1T1 CBFA2T3	1.25e-04	5	124	2	18586123
Pubmed	SGLT2 inhibition and renal urate excretion: role of luminal glucose, GLUT9, and URAT1.	SLC5A1 SLC5A2	1.25e-04	5	124	2	30427222
Pubmed	Myeloid translocation gene family members associate with T-cell factors (TCFs) and influence TCF-dependent transcription.	RUNX1T1 CBFA2T3	1.25e-04	5	124	2	18039847
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SHANK1 VGF OGT ADGRB2 ATF6B ITIH4 STRIP1 NEDD4 NCOR2 CLU DCHS1 SEC23A	1.77e-04	963	124	12	28671696
Pubmed	Kaiso directs the transcriptional corepressor MTG16 to the Kaiso binding site in target promoters.	RUNX1T1 CBFA2T3	1.87e-04	6	124	2	23251453
Pubmed	Multiple modification and protein interaction signals drive the Ring finger protein 11 (RNF11) E3 ligase to the endosomal compartment.	NEDD4 GGA1	1.87e-04	6	124	2	20676133
Pubmed	AML-associated translocation products block vitamin D(3)-induced differentiation by sequestering the vitamin D(3) receptor.	RUNX1T1 NCOR2	1.87e-04	6	124	2	12460926
Pubmed	The calcium-independent receptor for alpha-latrotoxin from human and rodent brains interacts with members of the ProSAP/SSTRIP/Shank family of multidomain proteins.	SHANK1 ADGRB2	1.87e-04	6	124	2	10964907
Pubmed	Activation of enteroendocrine membrane progesterone receptors promotes incretin secretion and improves glucose tolerance in mice.	PAQR5 PAQR7	2.62e-04	7	124	2	22933106
Pubmed	The embryonic preoptic area is a novel source of cortical GABAergic interneurons.	HMX3 DBX1	2.62e-04	7	124	2	19625528
Pubmed	Expression of NOL1/NOP2/sun domain (Nsun) RNA methyltransferase family genes in early mouse embryogenesis.	NSUN5 NSUN5P2	2.62e-04	7	124	2	23816522
Pubmed	Decreased expression of Glucagon-like peptide-1 receptor and Sodium-glucose co-transporter 2 in patients with proliferative diabetic retinopathy.	SLC5A1 SLC5A2	2.62e-04	7	124	2	36465606
Pubmed	Mutations in RNA Methyltransferase Gene NSUN5 Confer High Risk of Outflow Tract Malformation.	NSUN5 NSUN5P2	2.62e-04	7	124	2	33968922
Pubmed	TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.	FRAS1 HYOU1 LAMA5 POMGNT2 CLU	3.14e-04	164	124	5	32409323
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	RASGRF1 RPS4Y1 FBXO24 CLU NSUN5P2 TP53RK FHIP2B	3.26e-04	361	124	7	26167880
Pubmed	Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome.	MIIP RPS4Y2 RPS4X RPS4Y1 LAMA5 TFAP2C	3.45e-04	259	124	6	9811942
Pubmed	ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain.	RUNX1T1 CBFA2T3	3.48e-04	8	124	2	11533236
Pubmed	Sox9 Activation Highlights a Cellular Pathway of Renal Repair in the Acutely Injured Mammalian Kidney.	SLC5A1 SLC5A2	3.48e-04	8	124	2	26279573
Pubmed	Fras1 deficiency results in cryptophthalmos, renal agenesis and blebbed phenotype in mice.	FRAS1 LAMA5	3.48e-04	8	124	2	12766770
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	PRKD2 CEP85 MYO10 RPS4X POLR2G POLA2 FHIP2A BTBD7 PLD2 MAPK7 SEC23A GAREM1	3.49e-04	1038	124	12	26673895
Pubmed	Identification and Functional Characterization of a Novel Androgen Receptor Coregulator, EAP1.	OGT NCOR2 ARID1B	3.97e-04	40	124	3	34585037
Pubmed	B56-containing PP2A dephosphorylate ERK and their activity is controlled by the early gene IEX-1 and ERK.	PTPA MAPK7	4.47e-04	9	124	2	16456541
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	FRAS1 LAMA5 TWF2 MAPK7	4.63e-04	100	124	4	25807483
Pubmed	Placentation defects are highly prevalent in embryonic lethal mouse mutants.	NADK2 ARID1B UNK ARMH3	5.18e-04	103	124	4	29539633
Pubmed	Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia.	RPS4Y2 OGT RPS4X RPS4Y1	5.37e-04	104	124	4	26167872
Pubmed	PRMT1 interacts with AML1-ETO to promote its transcriptional activation and progenitor cell proliferative potential.	RUNX1T1 CBFA2T3	5.57e-04	10	124	2	22498736
Pubmed	Basement membrane distortions impair lung lobation and capillary organization in the mouse model for fraser syndrome.	FRAS1 LAMA5	5.57e-04	10	124	2	15623520
Pubmed	Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia.	ENTPD7 RUNX1T1 ITIH4 PLD2 SEC23A DMTN	6.49e-04	292	124	6	12819125
Pubmed	The tumour suppressor PTEN mediates a negative regulation of the E3 ubiquitin-protein ligase Nedd4.	RPS4Y2 RPS4X RPS4Y1 NEDD4	6.64e-04	110	124	4	18307411
Interaction	DKK3 interactions	VGF MYO1D LAMA5 PLEKHH1 ASPM CHST12	5.66e-06	75	120	6	int:DKK3
GeneFamily	O-linked N-acetylglucosaminyltransferases\|Tetratricopeptide repeat domain containing	OGT POMGNT2	1.12e-04	4	79	2	446
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PRKD2 RASGRF1 MYO10 PLEKHH1 AFAP1L2 FGD1	2.83e-04	206	79	6	682
GeneFamily	S ribosomal proteins	RPS4Y2 RPS4X RPS4Y1	4.36e-04	34	79	3	728
GeneFamily	Progestin and adipoQ receptor family	PAQR5 PAQR7	1.01e-03	11	79	2	930
GeneFamily	Mitochondrial complex IV: cytochrome c oxidase subunits	COX6A1 COX6A2	3.07e-03	19	79	2	643
GeneFamily	Zinc fingers MYND-type	RUNX1T1 CBFA2T3	3.75e-03	21	79	2	87
Coexpression	TABULA_MURIS_SENIS_PANCREAS_PANCREATIC_STELLATE_CELL_AGEING	RPS4Y2 RPS4X RPS4Y1	8.30e-06	9	123	3	MM3821
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-secretory_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	CLIC3 TFAP2C PTPA PWWP2B TP53RK SLC4A11 GAREM1	1.31e-06	196	124	7	547901c7a665770eff78eede69b8625b416c8186
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	CLIC3 TFAP2C PTPA PWWP2B TP53RK SLC4A11 GAREM1	1.31e-06	196	124	7	6e08d7ba67da161c2dca1a17c440ffb9d9b5bc3b
Disease	anxiety, vitamin D measurement	DOCK8 SEMA3E	3.40e-04	7	120	2	EFO_0004631, EFO_0005230
Disease	mitochondrial encephalomyopathy (implicated_via_orthology)	COX6A1 COX6A2	4.52e-04	8	120	2	DOID:890 (implicated_via_orthology)
Disease	Neuroblastoma	HGF DOCK8 ARID1B	9.33e-04	47	120	3	C0027819
Disease	Williams-Beuren syndrome (implicated_via_orthology)	NSUN5 NSUN5P2	1.66e-03	15	120	2	DOID:1928 (implicated_via_orthology)
Disease	anemia (implicated_via_orthology)	SLC4A3 SLC4A11	1.66e-03	15	120	2	DOID:2355 (implicated_via_orthology)
Disease	cytochrome-c oxidase deficiency disease (implicated_via_orthology)	COX6A1 COX6A2	2.14e-03	17	120	2	DOID:3762 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
AHFAPRLLPLDHYLV	ADGRB2	91	O60241
RRYPHYPSDLRDALH	SLC4A3	691	P48751
RVDLFYLHAPDHSAP	AKR7L	106	Q8NHP1
DAYRRSDLLLPHAHA	TFAP2C	141	Q92754
LYDGHPHPTNFRTRL	CSMD3	121	Q7Z407
NLHFPLYPHIRTTLR	B4GALNT3	141	Q6L9W6
HSAEILAAYRPAVHP	CLIC3	221	O95833
HYSRFHPPEQRLRLL	BCDIN3D	36	Q7Z5W3
SHPYSRPELLCSFRH	EVX2	326	Q03828
DPSPDHLYSFRILHK	AFAP1L2	406	Q8N4X5
REHPCPLSYVRAHLF	DUS1L	261	Q6P1R4
YRKLPDHHSPALFQD	AADACL4	151	Q5VUY2
LSHPPSRREHGYDAV	ARMH3	196	Q5T2E6
LHHEHPERKRAPQTY	ARID1B	2051	Q8NFD5
IAAEYRHPTVPHLYR	ASPM	861	Q8IZT6
VVEYALHRLHFPPAH	ABHD16B	226	Q9H3Z7
PDVPDHAAYHPFRRL	ITIH4	676	Q14624
HAAYHPFRRLAILPA	ITIH4	681	Q14624
RNESHDYPHRVAKFP	PTPN2	26	P17706
FPAQTDLHEHPLYRA	NSUN5	191	Q96P11
AHLPERLAPGRFDYI	PAQR5	236	Q9NXK6
RHFLYKPLDIPDHHR	MON1B	411	Q7L1V2
ALRHPFLAKYHDPDD	MAPK7	341	Q13164
ELHLRPESHSYLPEL	NCOR2	81	Q9Y618
DNAPRFLRPHYVAFL	DCHS1	2166	Q96JQ0
DYEARRPIYEPLHTH	PAQR7	296	Q86WK9
PRAYIFSDPHSRILE	FAM86B2	181	P0C5J1
IEHRDHPHSPIRYFT	FRAS1	1516	Q86XX4
HSRHRYALIPIPLAV	CD58	211	P19256
PDYRPTHRLHLVVYS	LPAR5	16	Q9H1C0
RPYTFKDFVLHPRSH	NEDD4	541	P46934
EELPRHAHLRFYTAP	NEIL1	91	Q96FI4
DYLRPLLSFAAAHVP	ENTPD7	146	Q9NQZ7
ESLHRYTLIPDHPDF	NRAP	1486	Q86VF7
YTLIPDHPDFTRARL	NRAP	1491	Q86VF7
HDFAPAPASVHIYLR	MST1L	411	Q2TV78
LDAHREFLHRPASGY	RUNX1T1	426	Q06455
HLCLPVRYTHSFPEA	NADK2	191	Q4G0N4
QRFALPAHYLERSPA	HMX3	101	A6NHT5
ARYLDHLLAHTAPHP	PHKA1	661	P46020
HAPPGVHRRYSALRE	PPFIA4	526	O75335
DFPREIHFHVHRYPI	LCLAT1	276	Q6UWP7
AHYLRHRVPPESERL	CCDC190	256	Q86UF4
LVPLHSHSYRKDHRP	PCNX1	266	Q96RV3
RLALFPHPHIHEYLL	FHIP2B	631	Q86V87
LRPRHYRAPSHDKVA	OR2V2	261	Q96R30
AFDRFVAICHPLHYP	OR51L1	121	Q8NGJ5
YHASSDPQHLRDPRL	DBX1	291	A6NMT0
PRNPYDLHFIREGHR	GAREM1	256	Q9H706
RYATLEHPFHCPRVL	FZD2	191	Q14332
VFPAQTDLHEHPLYR	NSUN5P2	6	Q63ZY6
SHEYTRRPAFPVIHL	DEFB125	61	Q8N687
YSRRHLGELPPHIFA	MYO10	121	Q9HD67
IRPHALTVHSYRAPA	PRKD2	136	Q9BZL6
AADAPLRLRSIHEYP	LILRB2	361	Q8N423
HPLRALRVFSYDHNP	LRRC10B	201	A6NIK2
HGFRILFHFARDPLP	GGA1	521	Q9UJY5
FRLPDFVNPVHYDLH	ENPEP	91	Q07075
DHQTPHRHKFLPERY	HGF	236	P14210
HVFHDDLLPLFYTLR	POMGNT2	166	Q8NAT1
EPARDHYLPDLHHLR	LAMA5	861	O15230
HERPEFIAYPHLRIR	COX6A1	66	P12074
HHFRDAYRHPDPREL	CBFA2T3	351	O75081
LYLRPHETAHVPFKF	NPHP4	1051	O75161
YPSRRTFHLHSDHPE	NPHP4	1356	O75161
PHVALYQARFPEHEL	HYOU1	111	Q9Y4L1
FLAEIPADPKLYRHH	DOCK8	1996	Q8NF50
NSYLHSGHRPRPEFR	COX6A2	46	Q02221
TLYSDPHHRVRFHNP	CEP85	196	Q6P2H3
LLHFRFLPDHTEPRR	CYP4F12	486	Q9HCS2
ACRIIYRSDEHHPPI	APCDD1	266	Q8J025
RREYPLSPDGHLHRQ	BTBD7	1006	Q9P203
LHRYEITFTLPPVHR	C20orf27	61	Q9GZN8
DIEQHAPYRHLPASR	FBXO24	481	O75426
YYNRVHILGEPRPHL	DALRD3	496	Q5D0E6
PNHHPFHRDLLRYAK	EXOC1	376	Q9NV70
RREFLEYHRPPGALH	EMILIN2	986	Q9BXX0
LSRLSLFPHPHIHEY	FHIP2A	661	Q5W0V3
EVLRRTPLYDFHLAH	AMT	31	P48728
PHFTYSLLEHVELPR	DMTN	66	Q08495
KPHRLGDSEHEPVYR	PWWP2B	336	Q6NUJ5
RHLPVFQHRRPDLYG	NIT1	306	Q86X76
TYRRAIELQPHFPDA	OGT	281	O15294
IDPRLHTPMYFFLRH	OR5G3	51	P0C626
RSNYERFLPPDAFIH	FUT5	291	Q11128
PHLARSYHHLFPLDA	GTF2H2C;	316	Q6P1K8
YPHSPLHVRALALVE	SLC4A11	706	Q8NBS3
LSHLESRYLPAHFSP	SLC52A3	206	Q9NQ40
QPPSALRRRHYHHAL	VGF	556	O15240
PCPRFAHQLVYDELH	MKLN1	581	Q9UL63
DVSHTFYPRRTPLQH	NT5DC3	511	Q86UY8
PSPQHHRALRFSYHL	FGD1	81	P98174
EPPHRYHIHRRKSFD	MIIP	291	Q5JXC2
RRYDRAHSNPDFLPV	STRIP1	781	Q5VSL9
IPHLVTHDARTIRYP	RPS4Y1	136	P22090
IPHLVTHDARTIRYP	RPS4Y2	136	Q8TD47
IPHLVTHDARTIRYP	RPS4X	136	P62701
VFVPSLRDVHHEPVY	POLA2	421	Q14181
PRYILTLHELLAHTP	RASGRF1	386	Q13972
LHSRFPMPRYIDTEH	SEC23A	696	Q15436
SFDPHHRAQPSYERP	SHANK1	861	Q9Y566
YRHPDRSQPAFLDAI	ATF6B	571	Q99941
YRDPLRIPREHVHNA	CHST12	196	Q9NRB3
QDTYHYLPFSLPHRR	CLU	201	P10909
HDLFNLPHDRPYFKR	UFSP2	231	Q9NUQ7
YFDPLINPISHRHSV	PRPF8	351	Q6P2Q9
PFKHVRDYRLRHLVP	UNC93B1	331	Q9H1C4
LAEHARTHTGERPYP	ZNF771	246	Q7L3S4
LALPFHDPYRHELRK	NXNL2	91	Q5VZ03
SLEHEILLHPRYFGP	POLR2G	6	P62487
YRPRPDSYHLLRHPV	SLC5A2	256	P31639
DSYHLLRHPVTGDLP	SLC5A2	261	P31639
PHLARSYHHLFPLDA	GTF2H2	316	Q13888
QLIDHPYLEPRHFVD	PTPA	261	Q15257
RPFHLFRLLIQYHEP	TBC1D23	166	Q9NUY8
PRRRAFLHYPDSAAA	MTHFSD	341	Q2M296
EDLFRHRNPPLHYEH	MYCBPAP	591	Q8TBZ2
IYDVRHRAAYHPDFP	SMC6	571	Q96SB8
DRELLPTFHHVSVYP	ST7L	491	Q8TDW4
LHFPRITYPLVHLAN	TMEM168	641	Q9H0V1
VLDRFHPRRYRHGAP	PLEKHH1	1171	Q9ULM0
IRSYPPLHLDHSLAA	ZNRF3	416	Q9ULT6
EHRAYSPAHPFRRPK	ZNRF3	436	Q9ULT6
HRFPKGYRHPALEAR	TP53RK	61	Q96S44
DYPDDAIRFARSHPL	SEMA3E	396	O15041
VRHHLRNRPDLYGPF	YIPF2	111	Q9BWQ6
YTPRADSFHIFRDPL	SLC5A1	256	P13866
HGPHDLRSPVYDIRE	UNK	151	Q9C0B0
DFLQLHRHDSYAPPR	PLD2	316	O14939
PSRVPRDAARYHFFL	TWF2	226	Q6IBS0
LYERPPHLFAIADAA	MYO1D	71	O94832