Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsmall GTPase binding

KNTC1 EPS8 DIAPH2 PPP6R1 RAB11FIP1 TBC1D21 EVI5L

8.98e-05321667GO:0031267
GeneOntologyMolecularFunctionGTPase binding

KNTC1 EPS8 DIAPH2 PPP6R1 RAB11FIP1 TBC1D21 EVI5L

1.82e-04360667GO:0051020
GeneOntologyMolecularFunctionhistone H3K14 acetyltransferase activity

KAT6A KAT6B

3.82e-049662GO:0036408
GeneOntologyMolecularFunctionphosphatidylinositol-3,4,5-trisphosphate binding

IRGM MYO10 FERMT2

5.70e-0449663GO:0005547
GeneOntologyMolecularFunctionmetal-dependent deubiquitinase activity

BRCC3 EIF3H

6.95e-0412662GO:0140492
GeneOntologyMolecularFunctionstore-operated calcium channel activity

TRPC4 TRPC5

6.95e-0412662GO:0015279
GeneOntologyMolecularFunctioninositol 1,4,5 trisphosphate binding

TRPC4 TRPC5

9.54e-0414662GO:0070679
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

KAT6A KAT6B

1.10e-0315662GO:0010484
GeneOntologyMolecularFunctionubiquitin-like protein peptidase activity

SENP1 USP28 BRCC3 EIF3H

1.10e-03137664GO:0019783
GeneOntologyCellularComponentMOZ/MORF histone acetyltransferase complex

KAT6A KAT6B

1.92e-047642GO:0070776
GeneOntologyCellularComponentH3 histone acetyltransferase complex

KAT6A KAT6B

2.55e-048642GO:0070775
GeneOntologyCellularComponentNMDA selective glutamate receptor complex

EPS8 GRIN2A

3.28e-049642GO:0017146
GeneOntologyCellularComponentpostsynaptic cytosol

SENP1 PLCB1 HTT

3.54e-0445643GO:0099524
DomainMOZ_SAS

KAT6A KAT6B

1.11e-045632PF01853
DomainHAT_MYST-type

KAT6A KAT6B

1.11e-045632IPR002717
DomainMYST_HAT

KAT6A KAT6B

1.11e-045632PS51726
DomainTRP_dom

TRPC4 TRPC5

1.67e-046632IPR013555
DomainTRP_2

TRPC4 TRPC5

1.67e-046632PF08344
DomainTRPC_channel

TRPC4 TRPC5

2.33e-047632IPR002153
Domain-

KAT6A SATL1 KAT6B

3.31e-04406333.40.630.30
DomainAcyl_CoA_acyltransferase

KAT6A SATL1 KAT6B

4.69e-0445633IPR016181
DomainTRP_channel

TRPC4 TRPC5

6.04e-0411632IPR004729
DomainJAB_MPN

BRCC3 EIF3H

7.23e-0412632SM00232
DomainJAMM/MPN+_dom

BRCC3 EIF3H

7.23e-0412632IPR000555
DomainJAB

BRCC3 EIF3H

7.23e-0412632PF01398
DomainH15

KAT6A KAT6B

8.53e-0413632SM00526
DomainH15

KAT6A KAT6B

8.53e-0413632PS51504
DomainHistone_H1/H5_H15

KAT6A KAT6B

9.93e-0414632IPR005818
PathwayREACTOME_NETRIN_1_SIGNALING

TRIO MYO10 TRPC4 TRPC5

2.69e-0544564M875
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

PHKB EPS8 SENP1 PBRM1 TRIO NAV3 SMU1 PLCB1 NME7 HTT

2.19e-08475661031040226
Pubmed

Association of mammalian trp4 and phospholipase C isozymes with a PDZ domain-containing protein, NHERF.

TRPC4 TRPC5 PLCB1

6.51e-08566310980202
Pubmed

Cyclic-Nucleotide- and HCN-Channel-Mediated Phototransduction in Intrinsically Photosensitive Retinal Ganglion Cells.

GNA14 TRPC4 TRPC5 PLCB1

6.91e-082166430270038
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

PDE2A SENP1 PBRM1 AP2B1 TRIO USP28 TRPC4 DIAPH2 PLCB1 PPP6R1 GRIN2A

1.85e-06963661128671696
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

KNTC1 BCL9L EPS8 PPP6R1 RAB11FIP1 NME7 NOTCH2 SAMD4A

2.06e-0644666824255178
Pubmed

Downregulation of TRPC4 and TRPC5 Inhibits Smooth Muscle Cell Proliferation without Affecting Endothelial Cell Proliferation.

TRPC4 TRPC5

3.55e-06266234899056
Pubmed

Corticolimbic expression of TRPC4 and TRPC5 channels in the rodent brain.

TRPC4 TRPC5

3.55e-06266217593972
Pubmed

Acute Treatment with a Novel TRPC4/C5 Channel Inhibitor Produces Antidepressant and Anxiolytic-Like Effects in Mice.

TRPC4 TRPC5

3.55e-06266226317356
Pubmed

Regulation of KAT6 Acetyltransferases and Their Roles in Cell Cycle Progression, Stem Cell Maintenance, and Human Disease.

KAT6A KAT6B

3.55e-06266227185879
Pubmed

A novel capacitative calcium entry channel expressed in excitable cells.

TRPC4 TRPC5

3.55e-0626629687496
Pubmed

Selective Gαi subunits as novel direct activators of transient receptor potential canonical (TRPC)4 and TRPC5 channels.

TRPC4 TRPC5

3.55e-06266222457348
Pubmed

ERα status of invasive ductal breast carcinoma as a result of regulatory interactions between lysine deacetylases KAT6A and KAT6B.

KAT6A KAT6B

3.55e-06266239505971
Pubmed

Conserved gating elements in TRPC4 and TRPC5 channels.

TRPC4 TRPC5

3.55e-06266223677990
Pubmed

Involvement of TRPC4 and 5 Channels in Persistent Firing in Hippocampal CA1 Pyramidal Cells.

TRPC4 TRPC5

3.55e-06266232033274
Pubmed

The first ankyrin-like repeat is the minimum indispensable key structure for functional assembly of homo- and heteromeric TRPC4/TRPC5 channels.

TRPC4 TRPC5

3.55e-06266217624425
Pubmed

TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A.

TRPC4 TRPC5

3.55e-06266230038709
Pubmed

The double PHD finger domain of MOZ/MYST3 induces α-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification.

KAT6A KAT6B

3.55e-06266224150941
Pubmed

MORF and MOZ acetyltransferases target unmethylated CpG islands through the winged helix domain.

KAT6A KAT6B

1.06e-05366236754959
Pubmed

Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory.

TRPC4 TRPC5

1.06e-05366228790178
Pubmed

Nuclear retention of full-length HTT RNA is mediated by splicing factors MBNL1 and U2AF65.

U2AF2 HTT

1.06e-05366226218986
Pubmed

SENP1-mediated deSUMOylation of USP28 regulated HIF-1α accumulation and activation during hypoxia response.

SENP1 USP28

1.06e-05366230622440
Pubmed

Differential PI(4,5)P2 sensitivities of TRPC4, C5 homomeric and TRPC1/4, C1/5 heteromeric channels.

TRPC4 TRPC5

1.06e-05366230755645
Pubmed

Modulation of mutant Huntingtin aggregates and toxicity by human myeloid leukemia factors.

MLF1 HTT

1.06e-05366227840155
Pubmed

TRPC1/4/5 channels contribute to morphine-induced analgesic tolerance and hyperalgesia by enhancing spinal synaptic potentiation and structural plasticity.

TRPC4 TRPC5

1.06e-05366232359120
Pubmed

Tandem PHD fingers of MORF/MOZ acetyltransferases display selectivity for acetylated histone H3 and are required for the association with chromatin.

KAT6A KAT6B

1.06e-05366223063713
Pubmed

Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels.

TRPC4 TRPC5

1.06e-05366228325835
Pubmed

Transient Receptor Potential C 1/4/5 Is a Determinant of MTI-101 Induced Calcium Influx and Cell Death in Multiple Myeloma.

TRPC4 TRPC5

1.06e-05366234199280
Pubmed

Dual action of the Gαq-PLCβ-PI(4,5)P2 pathway on TRPC1/4 and TRPC1/5 heterotetramers.

TRPC4 TRPC5

1.06e-05366230108272
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

KNTC1 EPS8 KRT5 SEPHS1 IFT74 USP28 RIOK3 PPP6R1

1.54e-0558866838580884
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PHKB SENP1 TRIO MBNL2 KAT6A U2AF2 CHD1L KAT6B NOTCH2 MAN1B1 HTT EVI5L

2.09e-051489661228611215
Pubmed

Interaction with dopamine D2 receptor enhances expression of transient receptor potential channel 1 at the cell surface.

TRPC4 TRPC5

2.12e-05466218261457
Pubmed

The phospholipid-binding protein SESTD1 is a novel regulator of the transient receptor potential channels TRPC4 and TRPC5.

TRPC4 TRPC5

2.12e-05466220164195
Pubmed

The interaction of ETV6 (TEL) and TIP60 requires a functional histone acetyltransferase domain in TIP60.

KAT6A KAT6B

2.12e-05466217980166
Pubmed

NMDA receptor-dependent synaptic activation of TRPC channels in olfactory bulb granule cells.

TRPC4 TRPC5

2.12e-05466222539836
Pubmed

Transient Receptor Potential Canonical 5-Scramblase Signaling Complex Mediates Neuronal Phosphatidylserine Externalization and Apoptosis.

TRPC4 TRPC5

2.12e-05466232110987
Pubmed

Recognition of unmodified histone H3 by the first PHD finger of bromodomain-PHD finger protein 2 provides insights into the regulation of histone acetyltransferases monocytic leukemic zinc-finger protein (MOZ) and MOZ-related factor (MORF).

KAT6A KAT6B

2.12e-05466221880731
Pubmed

Canonical transient receptor channel 5 (TRPC5) and TRPC1/4 contribute to seizure and excitotoxicity by distinct cellular mechanisms.

TRPC4 TRPC5

2.12e-05466223188715
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

AP2B1 MYO10 SMU1 RIOK3 PPP6R1 EIF3H RAB11FIP1 FERMT2 EVI5L SAMD4A

2.49e-051038661026673895
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

PHKB EPS8 KRT5 SENP1 TRIO IFT74 MLF1 NME7 FERMT2

3.26e-0585366928718761
Pubmed

Posttranslational acetylation of the human immunodeficiency virus type 1 integrase carboxyl-terminal domain is dispensable for viral replication.

KAT6A KAT6B

3.53e-05566217182677
Pubmed

Formation of novel TRPC channels by complex subunit interactions in embryonic brain.

TRPC4 TRPC5

3.53e-05566212857742
Pubmed

MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2.

KAT6A KAT6B

3.53e-05566211965546
Pubmed

Enhanced capacitative calcium entry and TRPC channel gene expression in human LES smooth muscle.

TRPC4 TRPC5

3.53e-05566212736151
Pubmed

TRUSS, TNF-R1, and TRPC ion channels synergistically reverse endoplasmic reticulum Ca2+ storage reduction in response to m1 muscarinic acetylcholine receptor signaling.

TRPC4 TRPC5

3.53e-05566220458742
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

TMEM67 PDE2A AP2B1 IFT74

4.04e-0510066425807483
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

SENP1 BRD8 PBRM1 KAT6A U2AF2 PPP6R1 RAB11FIP1 KAT6B NOTCH2 EVI5L

4.59e-051116661031753913
Pubmed

Calcium Channels Formed by Mammalian Trp Homologues.

TRPC4 TRPC5

5.29e-05666211390792
Pubmed

trp, a novel mammalian gene family essential for agonist-activated capacitative Ca2+ entry.

TRPC4 TRPC5

5.29e-0566628646775
Pubmed

TRPC proteins contribute to development of diabetic retinopathy and regulate glyoxalase 1 activity and methylglyoxal accumulation.

TRPC4 TRPC5

5.29e-05666229373286
Pubmed

TRPC channels regulate Ca2+-signaling and short-term plasticity of fast glutamatergic synapses.

TRPC4 TRPC5

5.29e-05666231536487
Pubmed

Transient receptor potential channels and their role in modulating radial glial-neuronal interaction: a signaling pathway involving mGluR5.

TRPC4 TRPC5

5.29e-05666225347706
Pubmed

MBNL and CELF proteins regulate alternative splicing of the skeletal muscle chloride channel CLCN1.

CELF4 MBNL2

5.29e-05666219720736
Pubmed

TRPM4 Conductances in Thalamic Reticular Nucleus Neurons Generate Persistent Firing during Slow Oscillations.

TRPC4 TRPC5

5.29e-05666232414784
Pubmed

Hypothalamic warm-sensitive neurons require TRPC4 channel for detecting internal warmth and regulating body temperature in mice.

TRPC4 TRPC5

5.29e-05666236476978
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

EPS8 MBNL2 MYO10 DIAPH2 CHD1L KAT6B NOTCH2

7.05e-0553666715840001
Pubmed

ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

BRD8 KAT6A KAT6B

7.11e-054266316387653
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

EPS8 MBNL2 MYO10 DIAPH2 CHD1L KAT6B NOTCH2

7.22e-0553866710512203
Pubmed

MxA, a member of the dynamin superfamily, interacts with the ankyrin-like repeat domain of TRPC.

TRPC4 TRPC5

7.40e-05766215757897
Pubmed

Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes.

KAT6A KAT6B

7.40e-05766218794358
Pubmed

Mechanism of stretch-induced activation of the mechanotransducer zyxin in vascular cells.

TRPC4 TRPC5

7.40e-05766223233529
Pubmed

RNA-seq analysis reveals TRPC genes to impact an unexpected number of metabolic and regulatory pathways.

TRPC4 TRPC5

7.40e-05766232350291
Pubmed

TRPC absence induces pro-inflammatory macrophages and gut microbe disorder, sensitizing mice to colitis.

TRPC4 TRPC5

7.40e-05766236592529
Pubmed

Functional role of TRPC proteins in vivo: lessons from TRPC-deficient mouse models.

TRPC4 TRPC5

7.40e-05766215336983
Pubmed

Parent stem cells can serve as niches for their daughter cells.

KRT5 NOTCH2

7.40e-05766226147083
Pubmed

TRPC absence induces pro-inflammatory macrophage polarization to promote obesity and exacerbate colorectal cancer.

TRPC4 TRPC5

7.40e-05766238835669
Pubmed

Dynamic microtubules catalyze formation of navigator-TRIO complexes to regulate neurite extension.

TRIO NAV3

7.40e-05766225065758
Pubmed

Subunit composition, molecular environment, and activation of native TRPC channels encoded by their interactomes.

TRPC4 TRPC5

7.40e-05766236257322
Pubmed

A transcriptional Map of the FMF region.

OR1F1 OR1F2P

9.86e-0586629653642
Pubmed

Subunit composition of mammalian transient receptor potential channels in living cells.

TRPC4 TRPC5

9.86e-05866212032305
Pubmed

Metabolism regulates the spontaneous firing of substantia nigra pars reticulata neurons via KATP and nonselective cation channels.

TRPC4 TRPC5

9.86e-05866225471572
Pubmed

Chaperone protein HYPK interacts with the first 17 amino acid region of Huntingtin and modulates mutant HTT-mediated aggregation and cytotoxicity.

MLF1 HTT

9.86e-05866225446099
Pubmed

Association of immunophilins with mammalian TRPC channels.

TRPC4 TRPC5

9.86e-05866215199065
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

PDE2A TRIO PLCB1 PPP6R1 GRIN2A

1.17e-0425166527507650
Pubmed

Homer binds TRPC family channels and is required for gating of TRPC1 by IP3 receptors.

TRPC4 TRPC5

1.27e-04966214505576
Pubmed

Tau exon 10, whose missplicing causes frontotemporal dementia, is regulated by an intricate interplay of cis elements and trans factors.

CELF4 U2AF2

1.27e-04966215009664
Pubmed

Identification of common binding sites for calmodulin and inositol 1,4,5-trisphosphate receptors on the carboxyl termini of trp channels.

TRPC4 TRPC5

1.27e-04966211290752
Pubmed

Phospholipase C-beta 1 is a GTPase-activating protein for Gq/11, its physiologic regulator.

GNA14 PLCB1

1.27e-0496621322796
Pubmed

Cellular subtype distribution and developmental regulation of TRPC channel members in the mouse dorsal root ganglion.

TRPC4 TRPC5

1.27e-04966217480026
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

EPS8 TRIO PLCB1 RAB11FIP1 FERMT2 NOTCH2

1.49e-0442166636976175
Pubmed

Heterogeneous distribution of TRPC proteins in the embryonic cortex.

TRPC4 TRPC5

1.58e-041066218989690
Pubmed

The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons.

TRPC4 TRPC5

1.58e-041066227177420
Pubmed

Increased ethanol resistance and consumption in Eps8 knockout mice correlates with altered actin dynamics.

EPS8 GRIN2A

1.58e-041066217018287
Pubmed

Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS.

IRGM GBP4

1.93e-041166224715728
Pubmed

Acetylation of HIV-1 integrase by p300 regulates viral integration.

KAT6A KAT6B

1.93e-041166216096645
Pubmed

Enlarged dendritic spines and pronounced neophobia in mice lacking the PSD protein RICH2.

EPS8 GRIN2A

2.31e-041266226969129
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PDE2A TRIO MYO10 KAT6A DIAPH2 PPP6R1 NOTCH2 HTT EVI5L

2.33e-04110566935748872
Pubmed

Genome-wide and candidate gene association study of cigarette smoking behaviors.

TRPC5 NAV3

2.73e-041366219247474
Pubmed

Melanopsin signalling in mammalian iris and retina.

TRPC4 TRPC5

2.73e-041366222051675
Pubmed

A cytoplasmic role of Wnt/β-catenin transcriptional cofactors Bcl9, Bcl9l, and Pygopus in tooth enamel formation.

BCL9L KRT5

3.18e-041466228174279
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

PHKB EPS8 KRT5 PDE2A AP2B1 TRIO ACO2 SMU1 GRIN2A FERMT2

3.48e-041431661037142655
Pubmed

Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders.

KNTC1 MYO10 SAMD4A

3.54e-047266325917818
Pubmed

Multiple roles of Notch signaling in the regulation of epidermal development.

KRT5 NOTCH2

3.67e-041566218410734
Pubmed

Cloning and characterization of the human phosphoinositide-specific phospholipase C-beta 1 (PLC beta 1).

GNA14 PLCB1

3.67e-041566211118617
Pubmed

Synergistic Signaling by Light and Acetylcholine in Mouse Iris Sphincter Muscle.

GNA14 PLCB1

3.67e-041566228578927
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

SEPHS1 SENP1 AP2B1 KAT6A PLCB1 RIOK3 KAT6B

4.64e-0473066734857952
Pubmed

Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families.

AP2B1 DIAPH2 RAB11FIP1 FERMT2 NOTCH2

4.69e-0433966537232246
Pubmed

Dynamic regulation of sarcoplasmic reticulum Ca(2+) stores by stromal interaction molecule 1 and sarcolipin during muscle differentiation.

TRPC4 TRPC5

4.74e-041766222411552
Pubmed

Huntingtin regulates mammary stem cell division and differentiation.

KRT5 HTT

5.32e-041866224749073
Pubmed

Induction of OTUD4 by viral infection promotes antiviral responses through deubiquitinating and stabilizing MAVS.

USP28 EIF3H

5.32e-041866230410068
Pubmed

An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse.

PBRM1 EIF3H

5.32e-041866224025402
Cytoband5q33.1

IRGM SLC36A3

6.47e-04266625q33.1
Cytoband3q25.1

SELENOT MLF1

1.04e-03336623q25.1
GeneFamilyOlfactory receptors, family 1

OR1F1 OR1F12P OR1F2P

9.36e-0540403147
GeneFamilyZinc fingers C2HC-type|PHD finger proteins|Lysine acetyltransferases

KAT6A KAT6B

5.62e-041640266
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

KAT6A KAT6B

6.36e-0417402486
GeneFamilyTransient receptor potential cation channels

TRPC4 TRPC5

1.74e-0328402249
GeneFamilyGlycosyltransferase family 6|Blood group antigens

ABCB6 RHD

3.03e-0337402454
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

MYO10 FERMT2

5.47e-03504021293
ToppCellIPF-Endothelial-VE_Peribronchial|Endothelial / Disease state, Lineage and Cell class

EPS8 TRIO MBNL2 DIAPH2 NAV3 PLCB1 SAMD4A

1.80e-08198667b8bd1ba268480f54451648e01631b615a3401144
ToppCellfacs-Heart-RV-24m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A GBP4 MYO10 NAV3 C16orf89

6.92e-06179665cf4d3828a3ce97932c68d06f5c65a070fc6d832c
ToppCellfacs-Heart-RV-24m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A GBP4 MYO10 NAV3 C16orf89

6.92e-061796656aa211670e5d6e013d0980967aa0a4f8f2905efe
ToppCellfacs-Heart-RV-24m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A GBP4 MYO10 NAV3 C16orf89

6.92e-06179665f9bc76ff25f88ee44c72499a0df9dc16f519c4cb
ToppCellCOVID-19-kidney-Fibroblast-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

EPS8 IRGM GNA14 TRPC4 GRIN2A

8.55e-0618766576bfe8c42430a230a8bdf299575c444fb7780f24
ToppCelldroplet-Mammary_Gland-nan-3m-Endothelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRGM PDE2A GBP4 MYO10 C16orf89

9.01e-061896651d4ad307c0606957dd7bf8da84450e5193cf4a50
ToppCelldroplet-Mammary_Gland-nan-3m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRGM PDE2A GBP4 MYO10 C16orf89

9.01e-06189665b952026044d5f6c0adce60cf24f6e0199e6f8757
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 GNA14 TRPC4 GRIN2A SAMD4A

1.10e-0519766580e153790cef37b743e22a7370ff5b3a6abf147d
ToppCelldistal-3-mesenchymal-Pericyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

EPS8 PDE2A TRPC4 PLCB1 FERMT2

1.18e-05200665911db29f254bb697610e720ba78816e2c7f57933
ToppCelldistal-mesenchymal-Pericyte-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

EPS8 MYO10 TRPC4 PLCB1 FERMT2

1.18e-05200665867935701fac71a3fe01578362da0676f959736c
ToppCelldistal-mesenchymal-Pericyte|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

EPS8 MYO10 TRPC4 PLCB1 FERMT2

1.18e-05200665fe31287cfb51d45643bdedbaa5efc03ed87263c6
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-cortical_neurons_1|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

CELF4 GBP4 TRIO GRIN2A

8.91e-051586641f94622186d8329357fa06785e03eeacf29ab1ce
ToppCellfacs-Lung-EPCAM-24m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A USP28 NAV3 SAMD4A

1.10e-04167664961e722442d786ab15d1e490941d2be265a9057a
ToppCellfacs-Lung-EPCAM-24m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A USP28 NAV3 SAMD4A

1.10e-041676643760efc35d4e7e9c2da1a20f9795ddea397e2206
ToppCellfacs-Heart-RV-24m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP4 MYO10 NAV3 C16orf89

1.13e-04168664831b000e26b4a7e7fdfa3988372e0281c45eadbb
ToppCellfacs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPS8 ADAMTS17 GRIN2A RAB11FIP1

1.13e-0416866406dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCell390C-Myeloid-Dendritic-pDC|390C / Donor, Lineage, Cell class and subclass (all cells)

KRT5 IRGM SEPHS1 RAB11FIP1

1.13e-041686645a2e7a52b7330dce30823695a7b9b26bc47a69ce
ToppCellfacs-Heart-RA-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPS8 ADAMTS17 GRIN2A RAB11FIP1

1.13e-041686641002f058a340763e3d8de0bd1f0547a903526ec6
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IRGM PDE2A PLCB1 C16orf89

1.29e-0417466440bb87d219aafab0357ab0d797efd38085fc0312
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYO10 TRPC4 PLCB1 FERMT2

1.41e-04178664185b44700f06ec58b3c09c80520502166c965fd6
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRGM GBP4 MYO10 DIAPH2

1.41e-0417866401dafd19de04eff459253eaa9a35debf8f3deedf
ToppCelldroplet-Liver-Npc-21m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT5 PDE2A GNA14 C16orf89

1.54e-04182664dc55de945c6f78f32eb3a1b3520835eb8417e068
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPS8 GBP4 ADAMTS17 NOTCH2

1.54e-04182664d3a037268f026eb2f84428b1821022503cef7756
ToppCelldroplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT5 PDE2A GNA14 C16orf89

1.54e-04182664010a7364da46101cb5068891fd7bc712ea8f13bd
ToppCelldroplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT5 PDE2A GNA14 C16orf89

1.54e-04182664b1ec2015aad1181eac1bbf8d48ad6f2f7ed24a01
ToppCellCOVID-19-kidney-Mito-rich_EC|kidney / Disease (COVID-19 only), tissue and cell type

GNA14 GBP4 NAV3 PLCB1

1.57e-041836643c4153479fc4ab2d073d92cee120480015555914
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GNA14 TRPC4 NAV3 GRIN2A

1.60e-04184664e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

EPS8 MYO10 TRPC4 PLCB1

1.63e-04185664a7dba7db79275884b2a93d8a16f2e0c739e71370
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-1|TCGA-Breast / Sample_Type by Project: Shred V9

SELENOT AP2B1 KAT6B HTT

1.70e-04187664a716b64ca03d9b61da765bf87f065ac9393303f1
ToppCellfacs-Heart-LV-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A MYO10 FERMT2 C16orf89

1.70e-041876641bc338c22d645a854f8d8eb8a064c441121fb673
ToppCellCOPD-Stromal-Pericyte|Stromal / Disease state, Lineage and Cell class

EPS8 MYO10 TRPC4 PLCB1

1.70e-04187664406ecd1dabb3ed8d871aef159f7bd1e383434953
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

EPS8 MYO10 TRPC4 PLCB1

1.70e-04187664a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCelldroplet-Fat-SCAT-30m-Endothelial-Cd36+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A GBP4 MYO10 FERMT2

1.74e-04188664e901a9bdf00b8e91806f445af66647373bf62661
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A GBP4 FERMT2 C16orf89

1.74e-041886648a87daf2851d9404df7c36f279db599574b47c69
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A GBP4 FERMT2 C16orf89

1.74e-041886640f426cca2ad7671fed9c6d2aa09f6a8627a518cd
ToppCellfacs-Heart-LV-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO10 NAV3 PLCB1 C16orf89

1.74e-04188664e5a8ca4613ab0bf1584b9e78959adf41d0bf379f
ToppCelldroplet-Fat-SCAT-30m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A GBP4 MYO10 FERMT2

1.74e-041886645cf060bb8adaefa9964187195d67993c1248ef47
ToppCellfacs-Heart-LV-18m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO10 NAV3 PLCB1 C16orf89

1.74e-04188664ed11e26ff4ef3d6314b5f5734062519b9aa285c1
ToppCellfacs-Heart-LV-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO10 NAV3 PLCB1 C16orf89

1.74e-041886640fc3a6562e6895f6fe7a93397eae842a75c60c93
ToppCelldroplet-Fat-SCAT-30m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A GBP4 MYO10 FERMT2

1.74e-04188664449f9602df3c83b2110eb479a00d428d1b55b423
ToppCellfacs-Heart-LV-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A GBP4 MYO10 C16orf89

1.77e-04189664393ec5954a12d6cf67bb435dcc34ff0b14c81e9f
ToppCellfacs-Trachea-nan-3m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A GBP4 MYO10 PLCB1

1.77e-04189664e3d65417997bdd3f9c312c0977dceb6eca061029
ToppCellfacs-Trachea-nan-3m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A GBP4 MYO10 PLCB1

1.77e-041896645559af03d9d612bb8dcf825e45744a9f8332bac8
ToppCellfacs-Heart-LV-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A GBP4 MYO10 C16orf89

1.77e-04189664bec57459ad4bab15b2532b57722549fec2e771fb
ToppCelldroplet-Mammary_Gland-nan-3m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRGM PDE2A GBP4 C16orf89

1.77e-0418966425781edbd08c6e413740b796ecc8ba1934bd3aa5
ToppCellfacs-Trachea-nan-3m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A GBP4 MYO10 PLCB1

1.77e-04189664f60ac60ab9b317a0196f0cbbe520ef7dbd19ac11
ToppCellfacs-Heart-LV-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A GBP4 MYO10 C16orf89

1.77e-04189664d424d2554595b2304219f7324406b401711af7c2
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A GBP4 MYO10 FERMT2

1.81e-04190664c8370c922e0cf0e0c36e02e1ed2b4053ad6a8073
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MBNL2 GRIN2A NOTCH2 SAMD4A

1.81e-041906641121eb607a984c59fbffe7220837fc178745aa55
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A GBP4 MYO10 FERMT2

1.81e-041906645174f91a880f85bb20806023aa68bd4b8ca24ea5
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

EPS8 MYO10 TRPC4 PLCB1

1.81e-041906644eb92aef1ee868f4537483d19014d947b7684612
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MBNL2 GRIN2A NOTCH2 SAMD4A

1.81e-04190664048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

EPS8 MYO10 TRPC4 PLCB1

1.81e-041906647be4341e2909101d756f14031c21e705eb45e69a
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IRGM PDE2A GBP4 MYO10

1.81e-041906642655df8c0883dd811fa7617301f9c4b0a4dd55ec
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A GBP4 MYO10 FERMT2

1.81e-0419066490e494cbfbed33a3a0d29bb7dae83f0c81580bcf
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYO10 TRPC4 PLCB1 FERMT2

1.85e-04191664716dfa7fccbd62b5f574792e68a26dc6c45511dc
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

USP28 ACO2 MLF1 SAMD4A

1.85e-041916645d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYO10 TRPC4 PLCB1 FERMT2

1.85e-041916641626b23a57429f835fddc052e3c57f63a4e5b8bb
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GNA14 TRPC4 NAV3 GRIN2A

1.88e-041926645105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GNA14 TRPC4 NAV3 GRIN2A

1.88e-04192664d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

EPS8 ADAMTS17 DIAPH2 PLCB1

1.88e-04192664356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GNA14 MLF1 FERMT2 SAMD4A

1.88e-041926646bba80887d6f64cf913a5c22f62baaddda417ce0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 GNA14 TRPC4 GRIN2A

1.92e-041936645b602b1702283184bd3943c2a6f2290b7c37e407
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 GNA14 TRPC4 GRIN2A

1.92e-04193664c8c21eee8c6c086dc2faf416669cd4a002870fbe
ToppCellIPF-Stromal-Pericyte|Stromal / Disease state, Lineage and Cell class

EPS8 MYO10 TRPC4 PLCB1

1.96e-041946643892b188f424ffb80f3c75a1b6709a21c1e1601d
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

MYO10 TRPC4 ADAMTS17 NAV3

2.00e-04195664603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellmild-B_cell|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP28 ZNF606 KAT6B EVI5L

2.00e-041956641e5f1967bcc898318f4e970b844b4a944eb168e5
ToppCellCOVID-19-kidney-Fibroblast-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

EPS8 GNA14 TRPC4 GRIN2A

2.00e-041956643d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MBNL2 PLCB1 GRIN2A CCDC136

2.00e-04195664787e95fb59c40bba784544b662fac37606ae1427
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MBNL2 NAV3 PLCB1 GRIN2A

2.00e-041956642e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCellCOVID-19-kidney-VWF+PLVAP+VCAM1+EC|kidney / Disease (COVID-19 only), tissue and cell type

PDE2A GNA14 GBP4 PLCB1

2.04e-04196664ac2c4a325efa8497a755cd31fb6a9d94d8e3bf42
ToppCellbackground-Endothelial_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

PDE2A GNA14 MYO10 PLCB1

2.04e-04196664e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A GNA14 GBP4 NAV3

2.04e-04196664ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG-25|World / Primary Cells by Cluster

MYO10 GRIN2A NOTCH2 SAMD4A

2.08e-041976649d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Pericyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

EPS8 PDE2A PLCB1 FERMT2

2.08e-0419766444cd1ece3633a31e8c9b667cd3cbc2749c06f478
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG|World / Primary Cells by Cluster

MYO10 GRIN2A NOTCH2 SAMD4A

2.08e-0419766461749ccafeb938c310cff1de5ff924a1c794325a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A GNA14 GBP4 NAV3

2.08e-041976640f467ef58f0c4dcc00b34b7b9639e03fb3ebe780
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A GNA14 GBP4 NAV3

2.12e-0419866431ba87552be97c9b78c9e82f98e96699ccb19824
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE2A GNA14 GBP4 NAV3

2.12e-041986640a172c6d997c7cfbad34b56e80121bd104dee67d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 MBNL2 TRPC4 NOTCH2

2.12e-04198664a860246bcea847249a78fd2e86ed8e04371060db
ToppCellmedial-mesenchymal-Pericyte-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

EPS8 MYO10 PLCB1 FERMT2

2.20e-04200664bbda454260016be92b539e220ecf7bcbbc6139e4
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

SENP1 AP2B1 TRIO NOTCH2

2.20e-042006641fa8422fd820d21e285a7e7c4c6fbd8b7277d2af
ToppCellmedial-mesenchymal-Pericyte|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

EPS8 MYO10 PLCB1 FERMT2

2.20e-04200664f36d7cb6345daccebf76997f998e35d959b59452
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Radial_glial-gliogenic/outer_RGCs_and_astrocytes|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

EPS8 MYO10 FERMT2 NOTCH2

2.20e-04200664792fef1f3e47ce5c131fedfad55075fc254aeead
ToppCelldistal-2-mesenchymal-Pericyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

EPS8 MYO10 TRPC4 PLCB1

2.20e-042006644ee0b2f56c2652435fa78bf6b3c90cea28df74e0
ToppCellmedial-2-mesenchymal-Pericyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

EPS8 MYO10 PLCB1 FERMT2

2.20e-042006649820fb4f6efcdfc6de937ef2302a98b48426baa3
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

KRT5 RAB11FIP1 C16orf89

2.64e-04846635d5e519a6652029b9f5275c8e648bbb123fd07b9
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

KRT5 RAB11FIP1 C16orf89

2.64e-0484663f7ce09c6fb2795b7aecabce00cb9830b3c1a7d0e
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

KRT5 RAB11FIP1 C16orf89

2.64e-04846632b477de422a9f6a8474cba05094577b88236a4f0
ToppCellStriatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb|Striatum / BrainAtlas - Mouse McCarroll V32

GNA14 ADAMTS17 CCDC63

3.79e-049566356350551af6a1ae15652d596002124d8f7885d4f
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Mgp_(Mgp)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

KRT5 GNA14 GSTT4

3.79e-049566353dde5363ea1d64386234e5bd4fbb28c057f2f21
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Mgp_(Mgp)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

KRT5 GNA14 GSTT4

3.79e-0495663ef0b7289b348617a76b4643479adc7e9701c0094
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Mgp_(Mgp)--|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

KRT5 GNA14 GSTT4

3.79e-04956638b4d6b25ce28811a76ea11713d881117e495ef5e
DiseaseMalignant neoplasm of breast

PHKB KRT5 PDE2A PBRM1 ACO2 TRPC4 PLCB1 ABCB6 KAT6B NOTCH2 RHD

1.11e-0510746111C0006142
DiseaseDrug habituation

CHD1L ZNF606 NME7 SAMD4A

9.63e-05115614C0013170
DiseaseSubstance-Related Disorders

CHD1L ZNF606 NME7 SAMD4A

9.63e-05115614C0236969
DiseaseDrug abuse

CHD1L ZNF606 NME7 SAMD4A

9.63e-05115614C0013146
DiseaseDrug Use Disorders

CHD1L ZNF606 NME7 SAMD4A

9.63e-05115614C0013222
DiseaseDrug Dependence

CHD1L ZNF606 NME7 SAMD4A

9.63e-05115614C1510472
DiseaseSubstance Dependence

CHD1L ZNF606 NME7 SAMD4A

9.63e-05115614C0038580
DiseaseSubstance Use Disorders

CHD1L ZNF606 NME7 SAMD4A

9.63e-05115614C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

CHD1L ZNF606 NME7 SAMD4A

9.63e-05115614C0029231
DiseasePrescription Drug Abuse

CHD1L ZNF606 NME7 SAMD4A

9.63e-05115614C4316881
DiseaseSubstance abuse problem

CHD1L ZNF606 NME7 SAMD4A

9.95e-05116614C0740858
Diseaseneurodegenerative disease (implicated_via_orthology)

ACO2 TRPC4 TRPC5 HTT

2.35e-04145614DOID:1289 (implicated_via_orthology)
Diseasenicotine dependence (implicated_via_orthology)

TRPC4 TRPC5

2.74e-0412612DOID:0050742 (implicated_via_orthology)
Diseasehydrocephalus (implicated_via_orthology)

TMEM67 NME7

7.03e-0419612DOID:10908 (implicated_via_orthology)
Diseasevital capacity

OR1F1 KNTC1 SENP1 ADAMTS17 PLCB1 RIOK3 GRIN2A EIF3H SAMD4A

9.40e-041236619EFO_0004312
DiseaseHuntington's disease (is_implicated_in)

GRIN2A HTT

1.03e-0323612DOID:12858 (is_implicated_in)
Diseasegastroesophageal reflux disease

CELF4 ADAMTS17 NAV3

1.21e-03101613EFO_0003948
Diseasebipolar disorder (is_implicated_in)

GRIN2A KAT6B

1.65e-0329612DOID:3312 (is_implicated_in)
Diseaseendometriosis

PLCB1 C2 EIF3H NME7

1.85e-03252614EFO_0001065
Diseasesocial communication impairment

CELF4 PLCB1

2.00e-0332612EFO_0005427

Protein segments in the cluster

PeptideGeneStartEntry
VAMQDATAQMAMLQF

ACO2

96

Q99798
QAELMQLDMEGMSQY

EVI5L

316

Q96CN4
QDYINLFCANMMDLN

C16orf89

221

Q6UX73
DADFDEVQYQMEMMR

EIF3H

91

O15372
IYMEMNFTNKALQHM

AP2B1

736

P63010
IMLMFQNAVMYNSSD

BRD8

776

Q9H0E9
DLMLMFQNAVMYNDS

BRD8

1171

Q9H0E9
YRMIQTNFIDMENMF

ABCB6

551

Q9NP58
EMDDMNEVYHLLYNM

DIAPH2

401

O60879
MNMVYNMFQHQSLGI

ADAMTS17

261

Q8TE56
HMEMQQNLDYYQTMS

P3H1

176

Q32P28
MTMENYSMAAQFVLD

OR8D1

1

Q8WZ84
SVNMNMNTLNAMNGY

KAT6B

1981

Q8WYB5
RMEVNETQYNEMFGM

NOTCH2

2256

Q04721
MFANMDNFLLTVMAY

OR1F12P

106

Q8NHA8
IDSMVEDFVMMFNNA

PBRM1

721

Q86U86
QISEMNMDYTITMFF

GABRQ

96

Q9UN88
AALNSVYLMMNNQMR

C2

341

P06681
MEMQFNRYDFIMVAS

IRGM

106

A1A4Y4
NFMKMFFDAELSQMQ

KRT5

301

P13647
SMAILSMLQDMNFIN

PDE2A

616

O00408
LMNMLMKLQEAANYS

NAV3

2346

Q8IVL0
FQGMNQEQAMAKYMA

MYO10

1931

Q9HD67
YFQMLKMHAMNTNNI

KNTC1

2146

P50748
ALFFMAEYTNIIMMN

MT-ND1

221

P03886
MEAQERSFQEYMAQM

GBP4

531

Q96PP9
MELAQELMETCYQMN

MAN1B1

546

Q9UKM7
MFVDMDNFLLAVMAY

OR1F1

106

O43749
CLMQMYFISELADMD

OR1F2P

96

Q96R84
VNSMNMNTLNAMNSY

KAT6A

1911

Q92794
MNAFMMNSEFNLSLL

HTT

2131

P42858
NTNTEMEEVMNDYNM

IFT74

161

Q96LB3
VVEMMQPMAANYNVF

GSTT4

171

A0A1W2PR19
RFTYVTELNNDMEMM

CCDC63

336

Q8NA47
QMTQMLDILQDYMDY

CHD1L

371

Q86WJ1
YQAMSQDMGNTQDMF

BCL9L

856

Q86UU0
KTAAAMLAQQMQFMF

MBNL2

91

Q5VZF2
MLNFMGATMEQDLYQ

EPS8

441

Q12929
EEEMMMFAALQYHIN

FERMT2

311

Q96AC1
FEISAMQMFNMDRVN

NME7

266

Q9Y5B8
MQMFNMDRVNVEEFY

NME7

271

Q9Y5B8
DMTMYEMNFSLLVED

PHKB

971

Q93100
NMCVMNMNSYDFATF

TMEM67

251

Q5HYA8
YQNIFTAMQAMIRAM

GNA14

76

O95837
IQFMRNNMTASMFDL

RAB11FIP1

146

Q6WKZ4
MVFFLSNMIENQCMS

SELENOT

131

P62341
NTQAEYQQGFHEMMM

TBC1D21

156

Q8IYX1
YQQGFHEMMMLFQLM

TBC1D21

161

Q8IYX1
QMDMNQGSASLYEMN

SATL1

31

Q86VE3
LNDEIINFYMNMLME

SENP1

466

Q9P0U3
EDVELAYQEAMMNMA

SEPHS1

231

P49903
AYQEAMMNMARLNRT

SEPHS1

236

P49903
SVYFMFMADNLQQMV

SLC36A3

151

Q495N2
VRTQAMYQMMDQGFV

BRCC3

136

P46736
LMEQMQALQVMYDAG

CCDC136

681

Q96JN2
FAAAQMQQMAALNMN

CELF4

291

Q9BZC1
LRNMSMRMFEEDTYN

CLDN34

111

H7C241
SDLMLAQMLQMEYDR

RIOK3

76

O14730
VISNIFNTDYHMNMM

RHD

156

Q02161
DLKYQAQDNFMMMDD

SMU1

251

Q2TAY7
SFQTMDQMVSNMRNY

MLF1

71

P58340
NIMFMQELQYLFALM

USP28

211

Q96RU2
FQTMDLAMQINMGMY

PLCB1

626

Q9NQ66
QAFMDFQMQRMTSAF

PPP6R1

551

Q9UPN7
TEEAMMDFFNAQMRL

U2AF2

161

P26368
LLNMLIAMMNNSYQL

TRPC5

616

Q9UL62
AALFSQMTYEEMMAL

SAMD4A

341

Q9UPU9
VLLNMLIAMMNNSYQ

TRPC4

611

Q9UBN4
AEAMLQANHYDMDMI

TRIO

971

O75962
DQLEMYHMNQSTAMR

ZNF606

181

Q8WXB4
NMAGVFYMLAAAMAL

GRIN2A

816

Q12879