Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessSRP-dependent cotranslational protein targeting to membrane, translocation

TRAM1 TRAM1L1

2.49e-058202GO:0006616
GeneOntologyBiologicalProcessSRP-dependent cotranslational protein targeting to membrane

TRAM1 TRAM1L1

3.09e-0427202GO:0006614
GeneOntologyBiologicalProcessorganelle inheritance

VPS13B MAPK1

3.33e-0428202GO:0048308
GeneOntologyBiologicalProcessGolgi inheritance

VPS13B MAPK1

3.33e-0428202GO:0048313
GeneOntologyBiologicalProcessprotein insertion into ER membrane

TRAM1 TRAM1L1

4.08e-0431202GO:0045048
GeneOntologyBiologicalProcessintracellular protein transmembrane transport

TRAM1 TRAM1L1

4.08e-0431202GO:0065002
GeneOntologyBiologicalProcesscotranslational protein targeting to membrane

TRAM1 TRAM1L1

4.35e-0432202GO:0006613
DomainTRAM1

TRAM1 TRAM1L1

3.97e-063222PF08390
DomainTRAM1

TRAM1 TRAM1L1

3.97e-063222IPR013599
DomainTranslocation_assoc_membrane

TRAM1 TRAM1L1

3.97e-063222IPR016447
DomainLeu-rich_rpt_typical-subtyp

LRRC8E RTN4RL1 LRRC46 LRRIQ4

4.99e-05177224IPR003591
DomainLRR_TYP

LRRC8E RTN4RL1 LRRC46 LRRIQ4

4.99e-05177224SM00369
DomainLRR

LRRC8E RTN4RL1 LRRC46 LRRIQ4

8.18e-05201224PS51450
DomainLRR_1

LRRC8E RTN4RL1 LRRC46 LRRIQ4

1.14e-04219224PF00560
DomainTLC

TRAM1 TRAM1L1

1.57e-0416222PS50922
DomainTLC-dom

TRAM1 TRAM1L1

1.57e-0416222IPR006634
DomainTLC

TRAM1 TRAM1L1

1.57e-0416222SM00724
DomainTRAM_LAG1_CLN8

TRAM1 TRAM1L1

1.57e-0416222PF03798
DomainLeu-rich_rpt

LRRC8E RTN4RL1 LRRC46 LRRIQ4

2.58e-04271224IPR001611
Domain-

LRRC8E RTN4RL1 LRRC46 LRRIQ4

4.90e-043212243.80.10.10
DomainL_dom-like

LRRC8E RTN4RL1 LRRC46 LRRIQ4

5.32e-04328224IPR032675
DomainLRR_8

LRRC8E RTN4RL1 LRRIQ4

1.02e-03171223PF13855
DomainIQ

LRRIQ4 MYO3B

4.06e-0381222SM00015
DomainIQ_motif_EF-hand-BS

LRRIQ4 MYO3B

4.98e-0390222IPR000048
DomainIQ

LRRIQ4 MYO3B

5.31e-0393222PS50096
DomainProtein_kinase_ATP_BS

ITK MYO3B MAPK1

9.59e-03379223IPR017441
DomainPROTEIN_KINASE_ATP

ITK MYO3B MAPK1

1.60e-02459223PS00107
DomainProt_kinase_dom

ITK MYO3B MAPK1

1.90e-02489223IPR000719
DomainPROTEIN_KINASE_DOM

ITK MYO3B MAPK1

1.94e-02493223PS50011
Pubmed

Nesprin-2-dependent ERK1/2 compartmentalisation regulates the DNA damage response in vascular smooth muscle cell ageing.

SYNE2 MAPK1

1.15e-06322225744025
Pubmed

Novel nuclear nesprin-2 variants tether active extracellular signal-regulated MAPK1 and MAPK2 at promyelocytic leukemia protein nuclear bodies and act to regulate smooth muscle cell proliferation.

SYNE2 MAPK1

2.29e-06422219861416
Pubmed

Clarifying the role of G protein signaling in HIV infection: new approaches to an old question.

ITK MAPK1

4.56e-051622220842205
Pubmed

Lem2 is essential for cardiac development by maintaining nuclear integrity.

SYNE2 MAPK1

1.87e-043222237067297
Pubmed

Spatiotemporal gene expression patterns reveal molecular relatedness between retinal laminae.

MOGS ABCA13

4.41e-044922231609468
Pubmed

Ring Finger Protein 11 acts on ligand-activated EGFR via the direct interaction with the UIM region of ANKRD13 protein family.

MOGS TRAM1

5.56e-045522231985874
Pubmed

Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice.

SLC47A1 MAPK1

5.76e-045622230104731
GeneFamilyTLC domain containing

TRAM1 TRAM1L1

2.50e-05101421374
GeneFamilySolute carriers

SLC47A1 SLC22A25

3.64e-02395142752
ToppCellCOVID-19-Heart-T_cell|Heart / Disease (COVID-19 only), tissue and cell type

ADGRG5 ABCA13 ITK MYO3B

2.12e-06190224e6c3a6e01fef6c5b49f72661d4fb0414ba9046bf
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRG5 RTN4RL1 ITK

5.13e-05148223438fe292d29be0206e1d9fd59ede5f8368f13665
ToppCellURO-Lymphocyte-T_NK-MAIT|URO / Disease, Lineage and Cell Type

SLC47A1 MYO3B SYNE2

6.96e-05164223cb42a70433b3968caca67f7aa98ea536cd90a0bc
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-Klrb1a/b/c(-)_NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG5 ITK MYO3B

7.09e-05165223651d40eadb1b34de618af94c167f43635729d43f
ToppCellnormal-na-Lymphocytic_NK-natural_killer_cell-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

ADGRG5 SYNE2 MAPK1

7.88e-05171223d339840626211a7bf1a9eb8f14d6c9509ab05e1c
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-Regulatory_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MOGS ITK MYO3B

8.01e-05172223d824e46c8040b0bb9235f9b8a2b35386b303caa0
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-regulatory_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MOGS ITK MYO3B

8.01e-0517222310a1d1838492b8ce6dea08844353b51571432c56
ToppCellAdult-Immune-natural_killer_cell-D175|Adult / Lineage, Cell type, age group and donor

ADGRG5 ITK SYNE2

9.17e-05180223fc59e28f39e7d4fb1bcc7205202cf39224b70d7b
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-MPO+_mono-neutrophil|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADGRG5 ABCA13 SLC47A1

9.63e-0518322301c7f01498a9894920edf8243e41187cbdf90688
ToppCellCOVID-19_Severe-gd_T|COVID-19_Severe / Disease condition and Cell class

ADGRG5 SYNE2 MAPK1

9.79e-05184223791f1bcb954aadc63d4117c400537d036f68734d
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ADGRG5 ITK SYNE2

1.01e-0418622371e87c4c755ab607689cb050f5a363cb520a0f53
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG5 RTN4RL1 ITK

1.01e-041862234dce1484653bb266e2305cbb306fb11eaf7892e2
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG5 RTN4RL1 ITK

1.01e-04186223e23e1246914e230369a716d0d666b98383bf8512
ToppCellControl-T_cells|Control / group, cell type (main and fine annotations)

ADGRG5 ITK SYNE2

1.03e-04187223f4e8e0eba58da89b56587667555a5d4754e108c7
ToppCellIPF-Lymphoid-NK|IPF / Disease state, Lineage and Cell class

ADGRG5 ITK SYNE2

1.06e-04189223d92e880162450f8d01e4b8784eb625275cb8e03e
ToppCellControl-Lymphoid-NK|World / Disease state, Lineage and Cell class

ADGRG5 ITK SYNE2

1.06e-0418922389ef0d0e66dc96cacaae6be7aacdaa884e8e66a8
ToppCellwk_08-11-Hematologic_Lymphocytic-T_&_ILC-ILC2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ADGRG5 RTN4RL1 ITK

1.06e-041892239c963f525ae765499b3e3229fead3aef018345ef
ToppCellCOPD-Lymphoid-NK|World / Disease state, Lineage and Cell class

ADGRG5 ITK SYNE2

1.06e-04189223c0ac160fa7e68b92414fb1600abcac8ad1a42232
ToppCellCOVID-19-T_cells-NK_cells|COVID-19 / group, cell type (main and fine annotations)

ADGRG5 ITK SYNE2

1.06e-04189223b699152dfbb8cd8ed724e1e5a51838f29b681b62
ToppCellSmart-seq2-blood_(Smart-seq2)-lymphocytic-innate_lymphocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ADGRG5 SYNE2 MAPK1

1.08e-041902231f890be1ac8613a098b271945f25a58c3c2530ab
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGRG5 ITK SYNE2

1.08e-04190223d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCellSmart-seq2-blood_(Smart-seq2)-lymphocytic-innate_lymphocytic-mature_NK_T_cell|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ADGRG5 SYNE2 MAPK1

1.08e-04190223d7cecf88451f736f8f3f6f4644504cf22846cd6e
ToppCellControl-Lymphoid-NK|Control / Disease state, Lineage and Cell class

ADGRG5 ITK SYNE2

1.08e-04190223f7bd8521a40ac30a64dc439f17e2f6c7d021ef65
ToppCellAdult-Immune-natural_killer_cell|Adult / Lineage, Cell type, age group and donor

ADGRG5 ITK SYNE2

1.09e-04191223758ec27e47d7662a5175305e98a1506c6859dbf7
ToppCellIPF-Lymphoid-NK|World / Disease state, Lineage and Cell class

ADGRG5 ITK SYNE2

1.09e-04191223f206159b9d5e84cf14a65bfdc008895cec5a8081
ToppCellIPF-Lymphoid|IPF / Disease state, Lineage and Cell class

ADGRG5 ITK SYNE2

1.13e-04193223bf9d50aea909a28dd1d0933af33842d5f1ae7818
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

VPS13B ITK SYNE2

1.13e-041932239337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADGRG5 SYNE2 MAPK1

1.14e-0419422324837a27b0041fe8c348225fa8b09b127d743603
ToppCellControl-Lymphoid|Control / Disease state, Lineage and Cell class

ADGRG5 ITK SYNE2

1.14e-04194223d5b124f15c953eeb7e8e990df44d7fa466f2b31f
ToppCellCOVID-19-lung-NK_cells|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADGRG5 ITK SYNE2

1.14e-041942234c92f18e0a34fb50630d4b260eaf179202508b6d
ToppCellnucseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADGRG5 ITK SYNE2

1.16e-04195223ffb40486f8097b2c08e8f3b3685d0b8cb8d1bc66
ToppCellnucseq-Immune-Lymphocytic_T/NK|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADGRG5 ITK SYNE2

1.16e-04195223b8124e8a23e6d37b40023608674e67285c6ffe84
ToppCellCOVID-19-lung-NK_cells|lung / Disease (COVID-19 only), tissue and cell type

ADGRG5 ITK SYNE2

1.16e-041952233b716ec7acc9a37af6bf40e711a539ce58d74aa4
ToppCellLAM-Lymphoid-NK|LAM / Condition, Lineage and Cell class

ADGRG5 ITK SYNE2

1.16e-04195223229374c72acef32b0e915379bdf3c82f351940e2
ToppCellBronchial_Brush-Epithelial|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

ABCA13 LRRC46 SYNE2

1.20e-04197223272c7f4e582ef57564450540242b0db766b78328
ToppCellT_cells-CTLs|World / Immune cells in Kidney/Urine in Lupus Nephritis

ADGRG5 ITK SYNE2

1.20e-041972232de34e20915a247bee75aa40495e23c20bb23e18
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADGRG5 SYNE2 MAPK1

1.22e-041982231a189b2b213099505c5d871fb8aedd55a97d44e0
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_ILC|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADGRG5 SYNE2 MAPK1

1.22e-04198223716c27d2a37b5f865b9d191e1851917340b400af
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD3|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADGRG5 ITK SYNE2

1.22e-041982233c23fb8a84d4e4a20f7fa60055c7b37fc45a29d5
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADGRG5 SYNE2 MAPK1

1.22e-04198223b12914c3c5b8dd628cb456cb40283c5016641872
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD3-NKT|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADGRG5 ITK SYNE2

1.22e-041982239ce9b3721fb8a154667211c29e60133412134c76
ToppCellSepsis-URO-Lymphocyte-T/NK-MAIT|URO / Disease, condition lineage and cell class

SLC47A1 MYO3B SYNE2

1.22e-0419822375db638278d4be2b0f406cd8871058a8352c5a86
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

VPS13B ITK SYNE2

1.23e-04199223f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-T-T_CD3-NKT|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADGRG5 ITK SYNE2

1.23e-041992238a64437fecdf0b13247f2582bd2ab55ab58f8066
ToppCellBronchial-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD11d|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADGRG5 ITK SYNE2

1.23e-04199223ed460ff7fb82d3f0eed689d56f50d40514f74b48
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-T-T_CD3|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADGRG5 ITK SYNE2

1.23e-041992233bf6d35e0f9be58f01a0b43cb707635595186bb0
ToppCellBronchial-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADGRG5 ITK SYNE2

1.25e-04200223b4d956067eb292cf2855c674d1eb05a5f2d988f7
ToppCellBronchial-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK-NK|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADGRG5 ITK SYNE2

1.25e-04200223d1cfc4ef6ae75c486427e393d98b84a2a7ec67fe
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK-NK|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADGRG5 ITK SYNE2

1.25e-042002230a6fc7eff94e2f71af9f31a01779aafd2f4a6699
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD56bright|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADGRG5 SLC22A25 ITK

1.25e-042002231db27223e307efca97502fca40ec5e4f8eea512b
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADGRG5 ITK SYNE2

1.25e-042002230b65855617fb7730de48facf411e2a8980f9f780
ToppCellBronchial-10x5prime-Immune_Lymphocytic-NK-ILC|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADGRG5 ITK SYNE2

1.25e-04200223c09bb5c994f098d86e873bd3f1d911b02563e6e2
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-NK-ILC|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADGRG5 ITK SYNE2

1.25e-042002234150170a135c37a7932bfb61acedac22dad01a3e
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3-Inhibitory_Neuron.Gad1Gad2.Cplx3-Egln3_(Cortical_subplate_interneuron)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ABCA13 MYO3B

3.10e-045322252a1f2a041e3ba2b11ed753f2f57b78e68b5cc0c
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3-Inhibitory_Neuron.Gad1Gad2.Cplx3-Egln3_(Cortical_subplate_interneuron)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ABCA13 MYO3B

3.10e-04532225fa009c9f30c77de6cece40a47da46241f1de54c
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Rln3_(parabrachial_pigmented_nucleus_(PBP))-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MROH7 MYO3B

8.52e-0488222b4620e79ea80681305434707e87cb02a7c6a5e4f
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Rln3_(parabrachial_pigmented_nucleus_(PBP))--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MROH7 MYO3B

8.52e-04882227992f8e621edf464bffcb70a6cc5f3b60c1d96f8
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Rln3_(parabrachial_pigmented_nucleus_(PBP))|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MROH7 MYO3B

8.52e-0488222b7b55f51af8ffa82813a4747580985a430da9ed1
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2-Th.Nr4a2_(Neuron.Gad1Gad2-Th.Nr4a2)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

DNHD1 MYO3B

9.71e-04942229664f74bc0168c92fb8a68cad628323c476f6103
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2-Th.Nr4a2_(Neuron.Gad1Gad2-Th.Nr4a2)--|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

DNHD1 MYO3B

9.71e-0494222c73e99890431750b74f984de5c82e33533ab708b
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2-Th.Nr4a2_(Neuron.Gad1Gad2-Th.Nr4a2)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

DNHD1 MYO3B

9.71e-04942221bda61101f45f5c4a68453087b880fdc6d9acfca
ToppCellParenchymal-10x5prime-Epithelial-Epi_submucosal-gland|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LRRC8E ABCA13

1.28e-0310822275d635fc5bb004418db2e1328c24d96b718f10b1
ToppCellParenchymal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Duct|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LRRC8E ABCA13

1.28e-031082229c7f3e25facfb54ef0be45044999bc36438bbea0
ToppCellLPS_only-Myeloid-Dendritic_cells-Monocytes-Macrophages|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC47A1 PAQR4

1.37e-031122229801227fe5a6f5ae1b6c5a9e7fa7f35c4c52efe1
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Cd74|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ADGRG5 SLC47A1

1.45e-031152224c7d78a246f1b44846fb959359515ef185530053
ToppCellMild-Myeloid-Macrophages-|Mild / Condition, Lineage, Cell class and cell subclass

TMEM145 SYNE2

1.63e-03122222b837456a6a236add2c0005cb3ca71568d631014e
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RTN4RL1 TRAM1L1

1.71e-031252225626eb77e542fcc87cd1fdf65f8623f3249ff9db
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MROH7 ABCA13

1.73e-031262226cb89754010d64875e115da6c5805efac7a4a82d
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MROH7 ABCA13

1.73e-0312622269b2525b92d1c7c35b21cc701f5fa52a9c1b94bb
ToppCellControl-Lymphocytic_NKT-T_cells-Erythroid|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITK TRAM1L1

1.73e-03126222f582c3ed43209dca3538e60062b3edd59bf2ad6b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 TRAM1L1

1.79e-03128222fbdefc29e087d36b17904c3f69302927157492a0
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ITK SYNE2

1.84e-03130222d47d4ff1263815896470d854d25306eb36919e70
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ITK SYNE2

1.84e-03130222ad57b210c96caedadc1027b4d7a56b1bc389b137
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Mast-Mast_cells-Mast-cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRG5 ITK

1.93e-0313322281189e8516a431d5890a0909f9fc7c82ec3442bc
ToppCellLPS-IL1RA-Lymphocytic_NKT-iNKT/MAIT-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRG5 ITK

1.93e-031332222ec3490cbf60152c3cece95eb566d749c9666517
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA13 TMEM145

1.98e-031352225113bb1713f99d01103b9a99de5d80393081cf87
ToppCellLPS_only-Hematopoietic_Mast-Mast_cells-Mast-cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRG5 ITK

2.01e-0313622282d7f90ef2a63a3137c331efd68c036cd0db3ac1
ToppCellE18.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

ADGRG5 RTN4RL1

2.04e-03137222b553958e7e6dcd887d860e34d3983cbb85cefaa6
ToppCellLPS-IL1RA-Hematopoietic_Mast-Mast_cells-Mast-cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRG5 ITK

2.10e-03139222f1d1a51a79afdddc82e73cd29b3240e3e973db28
ToppCellLPS-IL1RA-Lymphocytic_NKT-iNKT/MAIT-T-cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRRC46 ITK

2.10e-03139222ecc2a6ecc27748c50885cd4f0ad8a8cd1252aee6
ToppCellLymphoid-T_cells_(Cd8+_T_cell)|World / shred on cell class and cell subclass (v4)

ADGRG5 ITK

2.10e-03139222c85f50fb536f4df6fa4dbdebe48e1ecea1df1121
ToppCellCOVID-19_Mild-Neu_0|World / 5 Neutrophil clusters in COVID-19 patients

LRRC8E MYO3B

2.13e-0314022293f024473b1bb3bf93ae776fd6a8fc5e93d013f0
ToppCellTCGA-Bile_Duct-Solid_Tissue_Normal-Bile_duct_normal_tissue-Bile_duct_normal_tissue-4|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

SLC47A1 SLC22A25

2.13e-03140222744bfab59601efb23450a9bc87bcf541f77ad6b2
ToppCellTCGA-Bile_Duct-Solid_Tissue_Normal-Bile_duct_normal_tissue|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

SLC47A1 SLC22A25

2.13e-03140222bad9aa342bd5244263873936b55cbb95f69bdb5a
ToppCellTCGA-Bile_Duct-Solid_Tissue_Normal|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

SLC47A1 SLC22A25

2.13e-031402222c35c7d8b7e1101d1b74d7ce3da2364c5602c846
ToppCellTCGA-Bile_Duct-Solid_Tissue_Normal-Bile_duct_normal_tissue-Bile_duct_normal_tissue|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

SLC47A1 SLC22A25

2.13e-03140222deb9d97f1260fe1c4ad4ec3e1ecb111d79f13058
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-effector_CD8-positive,_alpha-beta_T_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TRAM1 SYNE2

2.16e-03141222bb77b8d12e33dc82859abd79e56a574781f815dc
ToppCellLPS-IL1RA-Hematopoietic_Mast-Mast_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRG5 ITK

2.19e-031422222a9a070e7c53ac593d46c6c5f6983f07d4413501
ToppCellLPS-IL1RA-Hematopoietic_Mast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRG5 ITK

2.19e-03142222f7d0d5ca9fc3dd929d4fdd59b71bfa623007e992
ToppCell3'_v3-Lung-Lymphocytic_T_CD4-Tfh|Lung / Manually curated celltypes from each tissue

ITK SYNE2

2.19e-03142222319812c84fad93276bf093f2ad78db02ae745bf4
ToppCellcritical-Lymphoid-NKT|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ABCA13 LRRC46

2.22e-03143222dca035bfbfd1665c04076c43da8bc18a1502b9de
ToppCellLPS-antiTNF-Hematopoietic_Mast-Mast_cells-Mast-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRG5 ITK

2.25e-03144222013223bb2f31eb5bebdbd0908b797d28b96c6f7b
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRG5 ITK

2.28e-03145222a9f5a32abcf3eb2c66bd65f2521a6dd4ce56c635
ToppCellAT1-AT2_cells-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

MROH7 MYO3B

2.28e-03145222cd5de30fd948024e3ad043c9411ce9f2722178b2
ToppCellCOVID-19-kidney-Mito-rich_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRRIQ4 SYNE2

2.28e-03145222afed661aef990edb8e7012ab67ace56443520c9f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TMEM145 SYNE2

2.32e-03146222deeb2c90a478deac7805e1f0d1466bf5bc42f746
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c03-MKI67|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABCA13 PAQR4

2.32e-03146222c0e1836845c083bf9d88a620da27acbfdea9fb20
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

RTN4RL1 MAPK1

2.38e-03148222223d6a640f3c34e73646a615593b9c0b4a4cbd6f
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRG5 ITK

2.41e-031492224fda987bc7bb6d1dbd41b8f1f8c1bc59613255a8
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ITK TMEM145

2.41e-03149222a6c24d8f3b5f08587f0a12cd63d166b68ea000c7
ComputationalGenes in the cancer module 277.

TRAM1 MAPK1

9.04e-045592MODULE_277
Diseaseintracerebral hemorrhage

OR52E4 RTN4RL1

6.33e-0516222EFO_0005669
Diseasemultiple sclerosis

TRAM1 LRRIQ4 ITK MAPK1

8.91e-04594224MONDO_0005301
Diseasesnoring measurement

RTN4RL1 TRAM1

1.78e-0384222EFO_0008341
DiseasePapillary Renal Cell Carcinoma

DNHD1 SYNE2

4.07e-03128222C1306837
DiseaseRenal Cell Carcinoma

DNHD1 SYNE2

4.07e-03128222C0007134
DiseaseSarcomatoid Renal Cell Carcinoma

DNHD1 SYNE2

4.07e-03128222C1266043
DiseaseChromophobe Renal Cell Carcinoma

DNHD1 SYNE2

4.07e-03128222C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

DNHD1 SYNE2

4.07e-03128222C1266044
Diseaseovarian neoplasm

LRRC46 MAPK1

4.46e-03134222C0919267
DiseaseMalignant neoplasm of ovary

LRRC46 MAPK1

4.65e-03137222C1140680
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

DNHD1 SYNE2

5.40e-03148222C0279702

Protein segments in the cluster

PeptideGeneStartEntry
YLTNHLGHTLLNLSG

ABCA13

4336

Q86UQ4
LFSILNGLHLHNLRG

DNHD1

1916

Q96M86
LLALLIQVHYHIGLN

MROH7

866

Q68CQ1
GGLHSLQYLYLQDNH

RTN4RL1

146

Q86UN2
KHYLDQLNHILGILG

MAPK1

231

P28482
GQNIPHYIHILLANL

OR52E4

266

Q8NGH9
SLHLLYLGNTGLHRL

LRRIQ4

281

A6NIV6
NLEGLQNLHSLYLQG

LRRC46

61

Q96FV0
GLLQNLQHLALSYNA

LRRC8E

696

Q6NSJ5
HNELGNIYTHGLALL

PAQR4

46

Q8N4S7
LNVNYLALGALHHYG

MOGS

756

Q13724
LGYNGAILQALAVHL

ADPRS

186

Q9NX46
GLTLHLQHLGNNVFL

SLC22A25

366

Q6T423
IPLLINYHQHNGGGL

ITK

316

Q08881
LHNIGYSAQHLDNLL

SYNE2

2491

Q8WXH0
ANYLFLHQLHLGVIG

SLC47A1

201

Q96FL8
LNNYVLGAQLSHGHV

ADGRG5

151

Q8IZF4
HITGAYLLYLNHLGL

TRAM1L1

206

Q8N609
HIAGAYLLNLNHLGL

TRAM1

206

Q15629
HLNCLVLLHELLNGY

VPS13B

2251

Q7Z7G8
IVNGIQLGIHLYAHG

TMEM145

381

Q8NBT3
ILYGALLGLQHLHNN

MYO3B

136

Q8WXR4