Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent activity

MYO1G ATP6V1A ERCC3 ABCF3 MYO9A SMC6 MCM5 MYO1B IDE RFC1 DNAH7 BPTF TRAP1 KIF14 DDX23 MACF1 ATP6V0D2 DNAH6 DYNC1I1 SLC27A2

5.21e-0761417620GO:0140657
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYO1G MYO9A MYO1B DNAH7 KIF14 DNAH6 DYNC1I1

8.50e-051181767GO:0003774
GeneOntologyMolecularFunctiongamma-catenin binding

APC PTPRJ CTNNA1

1.40e-04121763GO:0045295
GeneOntologyMolecularFunctionATP hydrolysis activity

ATP6V1A ERCC3 ABCF3 SMC6 MCM5 IDE RFC1 DNAH7 TRAP1 KIF14 DDX23 MACF1 DNAH6

1.52e-0444117613GO:0016887
GeneOntologyMolecularFunctionglycosyltransferase activity

GALNT14 PIGB B3GLCT PARP2 COLGALT2 STT3A GXYLT2 ALG14 PYGM FUT6

2.47e-0428817610GO:0016757
GeneOntologyCellularComponentcell leading edge

MYO1G MYLK APC HCN2 ACTR3 PLEK2 MTMR6 PTPRJ MACF1 CTNNA1 DAGLA PHLDB2 CDK6

2.80e-0450017313GO:0031252
GeneOntologyCellularComponentleading edge membrane

MYO1G APC HCN2 PLEK2 MTMR6 PTPRJ MACF1 DAGLA

3.72e-042101738GO:0031256
GeneOntologyCellularComponentadherens junction

APC FAT2 TJP1 DLG4 LRRC7 CTNNA1 PLEKHA7 SMAD7

3.97e-042121738GO:0005912
GeneOntologyCellularComponentcell-cell junction

NRAP MYLK APC TENM2 ACTR3 FAT2 PTPRJ TJP1 DLG4 LRRC7 CTNNA1 FLRT3 PLEKHA7 SMAD7

4.18e-0459117314GO:0005911
MousePhenoabnormal head morphology

ALX3 DOCK1 NCOA3 IFT140 ITGA11 B3GLCT ACD IFT172 KAT6A ESRP1 APC FBXO11 IDE RAX TGIF1 EHBP1L1 GTF2I PTPRJ NFE2L2 MITF ANKRD11 KIF14 TBX10 GNA11 PAX7 KAT6B TBX1 SMAD7 SORL1

2.24e-06112014229MP:0000432
MousePhenoabnormal axial skeleton morphology

DOCK1 NCOA3 TPTE IFT140 ITGA11 B3GLCT TRIM61 MYO9A SPEF2 KAT6A ESRP1 APC FBXO11 IDE PLEKHM1 PLEK2 HOXA6 TGIF1 BPTF EHBP1L1 NFE2L2 AASS P3H1 MITF ANKRD11 TBX10 GNA11 PRMT3 PAX7 MAPK6 KAT6B TBX1

1.95e-05145814232MP:0002114
MousePhenoshort face

B3GLCT FBXO11 TGIF1 ANKRD11

2.19e-05171424MP:0030066
MousePhenoabnormal craniofacial development

ALX3 IFT140 ITGA11 B3GLCT IFT172 KAT6A ESRP1 RAX GTF2I NFE2L2 MITF TBX10 PAX7 TBX1 SMAD7

2.75e-0542514215MP:0003935
MousePhenoabnormal facial morphology

ALX3 DOCK1 NCOA3 IFT140 ITGA11 B3GLCT IFT172 KAT6A ESRP1 FBXO11 IDE RAX TGIF1 EHBP1L1 GTF2I NFE2L2 MITF ANKRD11 TBX10 PAX7 TBX1 SMAD7 SORL1

4.33e-0591014223MP:0003743
MousePhenoabnormal craniofacial morphology

ALX3 DOCK1 NCOA3 IFT140 ITGA11 B3GLCT ACD IFT172 SPEF2 KAT6A ESRP1 APC FBXO11 IDE RAX TGIF1 EHBP1L1 GTF2I NFE2L2 MITF ANKRD11 KIF14 TBX10 GNA11 PAX7 KAT6B TBX1 SMAD7 SORL1

1.03e-04137214229MP:0000428
MousePhenocraniofacial phenotype

ALX3 DOCK1 NCOA3 IFT140 ITGA11 B3GLCT ACD IFT172 SPEF2 KAT6A ESRP1 APC FBXO11 IDE RAX TGIF1 EHBP1L1 GTF2I NFE2L2 MITF ANKRD11 KIF14 TBX10 GNA11 PAX7 KAT6B TBX1 SMAD7 SORL1

1.03e-04137214229MP:0005382
MousePhenoabnormal viscerocranium morphology

DOCK1 NCOA3 IFT140 ITGA11 B3GLCT KAT6A ESRP1 APC IDE TGIF1 EHBP1L1 NFE2L2 MITF ANKRD11 PAX7 KAT6B TBX1

1.07e-0459314217MP:0005274
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

ATP6V1A ERCC3 MCM5 NUP58 ACTR3B ACTR3 EFR3A TJP1 P3H1 USP7 KIF14 DDX23 MACF1 GNA11 CDC5L PHLDB2 NOS1AP CDK6

9.99e-096601781832780723
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

MARS2 ATP6V1A PCLO UBR4 TM9SF3 SMC6 NIPSNAP1 THUMPD3 MCM5 MYO1B IDE XPO1 RFC1 ACTR3 STT3A TRAP1 GTF2I NT5DC2 EIF3L KLHL23 USP7 KIF14 LTV1 PRMT3 CDC5L PLEKHA7

1.99e-0814251782630948266
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DOCK1 ATP6V1A SLC25A42 MYO9A TTC21A KAT6A PON2 IDE PLEKHM1 STT3A ZNF462 BPTF TLK1 GTF2I PTPRJ TJP1 TBC1D22A KLHL23 ANKRD11 MACF1 LRRC7 DCLK2 MAPK6 KAT6B DAGLA

1.86e-0714891782528611215
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

USP34 UBR4 MCM5 MYO1B XPO1 RFC1 ACTR3 BPTF GTF2I TJP1 EIF3L USP7 KIF14 DDX23 MACF1 CTNNA1

2.90e-076531781622586326
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

USP34 ATP6V1A PARP2 UBR4 TM9SF3 AGPAT4 PON2 MCM5 MYO1B XPO1 RFC1 ACTR3 STT3A TRAP1 GTF2I AASS EIF3L USP7 ASCC2 KIF14 DDX23 CTNNA1 CDC5L SLC27A2

3.83e-0714401782430833792
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

ERCC3 ABCF3 MYO9A UBR4 NIPSNAP1 THUMPD3 NEK7 RIOK3 MCM5 MYO1B XPO1 RFC1 ACTR3 PLEK2 GTF2I EIF3L USP7 DDX23 MACF1 LTV1 PRMT3 CDC5L PHLDB2

4.88e-0713531782329467282
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

ATP6V1A MYO9A TTC21A PCLO NIPSNAP1 APC XPO1 ACTR3B ACTR3 TJP1 EIF3L USP7 MACF1 DLG4 LRRC7 DCLK2 CTNNA1 CDC5L PLEKHA7 DNAH6 DAGLA UNC13A DYNC1I1

1.27e-0614311782337142655
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

USP34 TPTE MYO9A SYT17 SLCO3A1 DNAH7 BPTF MTMR6 AATK P3H1 SLC45A2 PLEKHA7

1.96e-064201781228065597
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

USP34 NCOA3 MCM5 XPO1 ZNF462 GTF2I USP7 DDX23 CDC5L

2.20e-06220178935785414
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

DOCK1 TPTE AFF2 UBR4 CCDC141 AATK NFE2L2 MITF USP7 PAX7 CAMSAP1 PLEKHA7

2.50e-064301781235044719
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

USP34 TPTE IFT172 UBR4 TM9SF3 PON2 MCM5 IDE XPO1 STT3A MTMR6 GTF2I TJP1 NT5DC2 DLG4 CTNNA1 CDC5L SORL1

2.97e-069741781828675297
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

MYO1B RFC1 FAT2 GTF2I USP7 MACF1 LTV1 CDC5L CAMSAP1

3.64e-06234178936243803
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

NCOA3 UBR4 TM9SF3 PON2 COLGALT2 IDE RFC1 CSMD2 DNAH7 EHBP1L1 AASS LTV1 TIGD5 CSPP1

5.86e-066381781431182584
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

GALNT14 TPTE MYLK RPS6KA5 KAT6A APC RIOK3 CPN1 STT3A TLK1 MTMR6 PRMT3 MAPK6 KAT6B CDK6

5.93e-067301781534857952
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

ATP6V1A ERCC3 C9orf78 PON2 MYO1B XPO1 RFC1 TRAP1 GTF2I NT5DC2 ASCC2 DDX23 PRMT3

7.01e-065601781335241646
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

ERCC3 PARP2 TM9SF3 MCM5 MYO1B XPO1 RFC1 ACTR3 STT3A PLEK2 GTF2I TJP1 EIF3L USP7 ASCC2 KIF14 LTV1 CTNNA1 CDC5L PHLDB2

7.66e-0612571782036526897
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

UBR4 NIPSNAP1 NEK7 PON2 RIOK3 MCM5 MYO1B ACTR3B ACTR3 CDAN1 TGIF1 TLK1 GTF2I EIF3L USP7 DDX23 PYGM LRRC7 CDC5L CDK6

1.04e-0512841782017353931
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

MARS2 PCLO UBR4 MCM5 MYO1B XPO1 STT3A TJP1 NT5DC2 MACF1 CTNNA1 CDK6

1.10e-054981781236634849
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

NCOA3 IFT140 IFT172 TTC21A TM9SF3 SMC6 NIPSNAP1 NEK7 ACTR3 TLK1 TRAP1 GTF2I EIF3L LTV1 CTNNA1 PLEKHA7 CSPP1 RSPH10B PHLDB2 SORL1

1.57e-0513211782027173435
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

USP34 ATP6V1A ABCF3 C9orf78 UBR4 THUMPD3 MCM5 IDE XPO1 ACTR3 CDAN1 TRAP1 EHBP1L1 GTF2I P3H1 EIF3L USP7 MACF1 LTV1 PRMT3 CTNNA1

1.93e-0514551782122863883
Pubmed

Proteomic and Interactome Approaches Reveal PAK4, PHB-2, and 14-3-3η as Targets of Overactivated Cdc42 in Cellular Responses to Genomic Instability.

ATP6V1A PDE6C XPO1 ACTR3 P3H1 NQO1 CTNNA1 CDC5L

2.25e-05225178831478661
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

USP34 ZNF462 TLK1 AATK MACF1 CDC5L KAT6B DAGLA

2.25e-05225178812168954
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

ATP6V1A PCLO UBR4 NIPSNAP1 APC DGKG ACTR3B TENM2 TRAP1 TJP1 USP7 MACF1 DLG4 LRRC7 DCLK2 CAMSAP1 UNC13A NOS1AP

2.45e-0511391781836417873
Pubmed

Control of cellular redox status and upregulation of quinone reductase NQO1 via Nrf2 activation by alpha-lipoic acid in human leukemia HL-60 cells.

NFE2L2 NQO1

2.60e-052178218813798
Pubmed

Dual-negative expression of Nrf2 and NQO1 predicts superior outcomes in patients with non-small cell lung cancer.

NFE2L2 NQO1

2.60e-052178228501854
Pubmed

Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone.

NFE2L2 NQO1

2.60e-052178232007910
Pubmed

MLCK-dependent exchange and actin binding region-dependent anchoring of ZO-1 regulate tight junction barrier function.

MYLK TJP1

2.60e-052178220404178
Pubmed

Exosomes derived from human umbilical cord mesenchymal stem cells ameliorate experimental non-alcoholic steatohepatitis via Nrf2/NQO-1 pathway.

NFE2L2 NQO1

2.60e-052178236096356
Pubmed

Proteomic identification of overexpressed adenomatous polyposis coli and cyclin B3 during endoderm differentiation from human embryonic stem cells.

APC CCNB3

2.60e-052178221404461
Pubmed

Identification of a novel nuclear localization signal in Tbx1 that is deleted in DiGeorge syndrome patients harboring the 1223delC mutation.

TBX10 TBX1

2.60e-052178215703190
Pubmed

Bridging of nucleosome-proximal DNA double-strand breaks by PARP2 enhances its interaction with HPF1.

PARP2 HPF1

2.60e-052178233141820
Pubmed

Docosahexanoic acid signals through the Nrf2-Nqo1 pathway to maintain redox balance and promote neurite outgrowth.

NFE2L2 NQO1

2.60e-052178233502893
Pubmed

APC is required for muscle stem cell proliferation and skeletal muscle tissue repair.

APC PAX7

2.60e-052178226304725
Pubmed

Luteolin sensitizes two oxaliplatin-resistant colorectal cancer cell lines to chemotherapeutic drugs via inhibition of the Nrf2 pathway.

NFE2L2 NQO1

2.60e-052178224761924
Pubmed

ERK3 signals through SRC-3 coactivator to promote human lung cancer cell invasion.

NCOA3 MAPK6

2.60e-052178222505454
Pubmed

Association of Genetic Variations in NRF2, NQO1, HMOX1, and MT with Severity of Coronary Artery Disease and Related Risk Factors.

NFE2L2 NQO1

2.60e-052178231332605
Pubmed

ERα status of invasive ductal breast carcinoma as a result of regulatory interactions between lysine deacetylases KAT6A and KAT6B.

KAT6A KAT6B

2.60e-052178239505971
Pubmed

Modulation of Nqo1 activity intercepts anoikis resistance and reduces metastatic potential of hepatocellular carcinoma.

NFE2L2 NQO1

2.60e-052178231968140
Pubmed

Inflammation, oxidative stress, and higher expression levels of Nrf2 and NQO1 proteins in the airways of women chronically exposed to biomass fuel smoke.

NFE2L2 NQO1

2.60e-052178229363060
Pubmed

The double PHD finger domain of MOZ/MYST3 induces α-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification.

KAT6A KAT6B

2.60e-052178224150941
Pubmed

Activation of Akt and JNK/Nrf2/NQO1 pathway contributes to the protective effect of coptisine against AAPH-induced oxidative stress.

NFE2L2 NQO1

2.60e-052178227903425
Pubmed

Liver expression of Nrf2-related genes in different liver diseases.

NFE2L2 NQO1

2.60e-052178226459724
Pubmed

Nrf2-dependent induction of NQO1 in mouse aortic endothelial cells overexpressing catalase.

NFE2L2 NQO1

2.60e-052178221569840
Pubmed

Mesenchymal MACF1 Facilitates SMAD7 Nuclear Translocation to Drive Bone Formation.

MACF1 SMAD7

2.60e-052178232143362
Pubmed

NQO1 and NFE2L2 polymorphisms, fruit and vegetable intake and smoking and the risk of colorectal adenomas in an endoscopy-based population.

NFE2L2 NQO1

2.60e-052178218074351
Pubmed

The influence of fruit and vegetable consumption and genetic variation on NAD(P)H:quinone oxidoreductase (NQO1) phenotype in an endoscopy-based population.

NFE2L2 NQO1

2.60e-052178218444152
Pubmed

Nuclear factor-E2-related factor 2 expression in liver is critical for induction of NAD(P)H:quinone oxidoreductase 1 during cholestasis.

NFE2L2 NQO1

2.60e-052178217278884
Pubmed

ARP3beta, the gene encoding a new human actin-related protein, is alternatively spliced and predominantly expressed in brain neuronal cells.

ACTR3B ACTR3

2.60e-052178210806390
Pubmed

Laminar flow induction of antioxidant response element-mediated genes in endothelial cells. A novel anti-inflammatory mechanism.

NFE2L2 NQO1

2.60e-052178212370194
Pubmed

ESRP1 controls biogenesis and function of a large abundant multiexon circRNA.

DOCK1 ESRP1

2.60e-052178238015468
Pubmed

Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin.

PARP2 HPF1

2.60e-052178232939087
Pubmed

Regulation of KAT6 Acetyltransferases and Their Roles in Cell Cycle Progression, Stem Cell Maintenance, and Human Disease.

KAT6A KAT6B

2.60e-052178227185879
Pubmed

Loss of ANCO1 repression at AIB1/YAP targets drives breast cancer progression.

NCOA3 ANKRD11

2.60e-052178231788936
Pubmed

USP7 inactivation suppresses APC-mutant intestinal hyperproliferation and tumor development.

APC USP7

2.60e-052178236669491
Pubmed

BPTF transduces MITF-driven prosurvival signals in melanoma cells.

BPTF MITF

2.60e-052178227185926
Pubmed

Association between 18F-FDG uptake in PET/CT, Nrf2, and NQO1 expression and their prognostic significance in non-small cell lung cancer.

NFE2L2 NQO1

2.60e-052178230868898
Pubmed

Site-directed mutagenesis of cysteine to serine in the DNA binding region of Nrf2 decreases its capacity to upregulate antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene.

NFE2L2 NQO1

2.60e-052178211948402
Pubmed

Leads from xenobiotic metabolism genes for Parkinson's disease among north Indians.

PON2 NQO1

2.60e-052178222016051
Pubmed

MITF protects against oxidative damage-induced retinal degeneration by regulating the NRF2 pathway in the retinal pigment epithelium.

NFE2L2 MITF

2.60e-052178232361183
Pubmed

Differentiation-dependent expression of NADP(H):quinone oxidoreductase-1 via NF-E2 related factor-2 activation in human epidermal keratinocytes.

NFE2L2 NQO1

2.60e-052178221524888
Pubmed

NCOA3, a new fusion partner for MOZ/MYST3 in M5 acute myeloid leukemia.

NCOA3 KAT6A

2.60e-052178217805331
Pubmed

Mitochondrial NADP(H) deficiency due to a mutation in NADK2 causes dienoyl-CoA reductase deficiency with hyperlysinemia.

NADK2 AASS

2.60e-052178224847004
Pubmed

Nitric oxide-induced transcriptional up-regulation of protective genes by Nrf2 via the antioxidant response element counteracts apoptosis of neuroblastoma cells.

NFE2L2 NQO1

2.60e-052178214985350
Pubmed

Chromatin-Remodelling Complex NURF Is Essential for Differentiation of Adult Melanocyte Stem Cells.

BPTF MITF

2.60e-052178226440048
Pubmed

Metabolic targeting of NRF2 potentiates the efficacy of the TRAP1 inhibitor G-TPP through reduction of ROS detoxification in colorectal cancer.

TRAP1 NFE2L2

2.60e-052178236113636
Pubmed

Activation of PARP2/ARTD2 by DNA damage induces conformational changes relieving enzyme autoinhibition.

PARP2 HPF1

2.60e-052178234108479
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

C9orf78 SMC6 APC IDE XPO1 ACTR3 TLK1 TRAP1 GTF2I TJP1 P3H1 EIF3L KIF14 DDX23 PYGM LTV1 CTNNA1 CDC5L

2.94e-0511551781820360068
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

TPTE MYO1B IDE XPO1 ACTR3 EFR3A MTMR6 PTPRJ TJP1 P3H1 USP7 KIF14 CTNNA1 CDC5L PLEKHA7 CSPP1 NOS1AP

3.04e-0510491781727880917
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

MARS2 ATP6V1A NADK2 UBR4 NIPSNAP1 THUMPD3 APC PON2 MYO1B XPO1 RFC1 STT3A BPTF MTMR6 TJP1 P3H1 EIF3L MACF1 CDK6

4.05e-0512971781933545068
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

USP34 PCLO UBR4 FBXO11 CDAN1 BPTF P3H1 NT5DC2 USP7 CDC5L

4.09e-053961781026687479
Pubmed

Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.

ATP6V1A UBR4 MCM5 MYO1B XPO1 ACTR3 USP7 CTNNA1 CDC5L CDK6

4.35e-053991781037536630
Pubmed

A human MAP kinase interactome.

DOCK1 IFT140 ZBTB8OS RPS6KA5 MYO9A APC NUP58 TLK1 MACF1 CTNNA1 MAPK6

4.55e-054861781120936779
Pubmed

Nf2 fine-tunes proliferation and tissue alignment during closure of the optic fissure in the embryonic mouse eye.

TJP1 MITF CTNNA1

4.60e-0514178333075808
Pubmed

USP7 Is a Tumor-Specific WNT Activator for APC-Mutated Colorectal Cancer by Mediating β-Catenin Deubiquitination.

APC USP7 CTNNA1

7.03e-0516178329045831
Pubmed

Spatial and temporal regulation of Wnt/beta-catenin signaling is essential for development of the retinal pigment epithelium.

RAX MITF CTNNA1

7.03e-0516178319596317
Pubmed

Dlg3 trafficking and apical tight junction formation is regulated by nedd4 and nedd4-2 e3 ubiquitin ligases.

TJP1 DLG4 DYNC1I1

7.03e-0516178321920314
Pubmed

A directed protein interaction network for investigating intracellular signal transduction.

ATP6V1A IFT140 RPS6KA5 C9orf78 UBR4 NIPSNAP1 MCM5 NUP58 RFC1 PLEKHM1 TGIF1 BPTF EIF3L KLHL23 CTNNA1 MAPK6 DYNC1I1

7.13e-0511241781721900206
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

USP34 NCOA3 ATP6V1A ERCC3 UBR4 SMC6 MCM5 XPO1 RFC1 BPTF GTF2I EIF3L NQO1 USP7 DDX23 CDC5L

7.18e-0510141781632416067
Pubmed

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.

TENM2 TJP1 MACF1 PYGM DLG4 LRRC7 CAMSAP1

7.41e-05197178736604605
Pubmed

Replication of previous genome-wide association studies of bone mineral density in premenopausal American women.

RPS6KA5 DGKG CPN1 SMAD7

7.67e-0544178420200978
Pubmed

Modulation of Nrf2/Keap1 system by Wasabi 6-methylthiohexyl isothiocyanate in ARE-mediated NQO1 expression.

NFE2L2 NQO1

7.79e-053178223390006
Pubmed

Bardoxolone ameliorates TGF-β1-associated renal fibrosis through Nrf2/Smad7 elevation.

NFE2L2 SMAD7

7.79e-053178231059771
Pubmed

Exclusion of mutations in TGIF, ALX3, and ALX4 genes in patients with the syndrome of frontonasal dysgenesis, callosal agenesis, basal encephalocele, and eye anomalies.

ALX3 TGIF1

7.79e-053178222496059
Pubmed

A role for ZO-1 and PLEKHA7 in recruiting paracingulin to tight and adherens junctions of epithelial cells.

TJP1 PLEKHA7

7.79e-053178221454477
Pubmed

HPF1 completes the PARP active site for DNA damage-induced ADP-ribosylation.

PARP2 HPF1

7.79e-053178232028527
Pubmed

HIV-1 gp120 induces antioxidant response element-mediated expression in primary astrocytes: role in HIV associated neurocognitive disorder.

NFE2L2 NQO1

7.79e-053178221756955
Pubmed

Serine-linked PARP1 auto-modification controls PARP inhibitor response.

PARP2 HPF1

7.79e-053178234210965
Pubmed

Regulation of HER2 oncogene transcription by a multifunctional coactivator/corepressor complex.

NCOA3 ANKRD11

7.79e-053178224678732
Pubmed

Bach1 competes with Nrf2 leading to negative regulation of the antioxidant response element (ARE)-mediated NAD(P)H:quinone oxidoreductase 1 gene expression and induction in response to antioxidants.

NFE2L2 NQO1

7.79e-053178215734732
Pubmed

Lipopolysaccharide-induced expression of NAD(P)H:quinone oxidoreductase 1 and heme oxygenase-1 protects against excessive inflammatory responses in human monocytes.

NFE2L2 NQO1

7.79e-053178218981090
Pubmed

Association of the APC tumor suppressor protein with catenins.

APC CTNNA1

7.79e-05317828259519
Pubmed

[Effects of inorganic arsenic on mRNA expression of Nrf2 and Nrf2-regulated downstream anti-oxidant enzymes in Chang hepatocytes].

NFE2L2 NQO1

7.79e-053178221861350
Pubmed

[Effect of lipoxin A(4) on lipopolysaccharide-induced oxidant stress in human umbilical vein endothelial cells].

NFE2L2 NQO1

7.79e-053178221211285
Pubmed

Protease-activated receptor-2 activates NQO-1 via Nrf2 stabilization in keratinocytes.

NFE2L2 NQO1

7.79e-053178224326025
Pubmed

Methane Alleviates Acetaminophen-Induced Liver Injury by Inhibiting Inflammation, Oxidative Stress, Endoplasmic Reticulum Stress, and Apoptosis through the Nrf2/HO-1/NQO1 Signaling Pathway.

NFE2L2 NQO1

7.79e-053178231781345
Pubmed

Densin-180, a synaptic protein, links to PSD-95 through its direct interaction with MAGUIN-1.

DLG4 LRRC7

7.79e-053178212390249
Pubmed

Nrf2 activation does not affect adenoma development in a mouse model of colorectal cancer.

APC NFE2L2

7.79e-053178234526660
Pubmed

The colorectal tumour suppressor APC is present in the NMDA-receptor-PSD-95 complex in the brain.

APC DLG4

7.79e-053178211029657
Pubmed

Localisation of the gene encoding diacylglycerol kinase 3 (DAGK3) to human chromosome 3q27-28 and mouse chromosome 16.

DGKG TBX1

7.79e-05317828585934
Pubmed

APC regulation of ESRP1 and p120-catenin isoforms in colorectal cancer cells.

ESRP1 APC

7.79e-053178233237836
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

NCOA3 KAT6A KAT6B

2.40e-04171323486
GeneFamilyPRD class homeoboxes and pseudogenes

ALX3 VSX1 RAX2 RAX PAX7

5.69e-04921325521
GeneFamilyIntraflagellar transport proteins|Tetratricopeptide repeat domain containing

IFT140 IFT172 TTC21A

6.88e-04241323615
GeneFamilyUbiquitin protein ligase E3 component n-recognins

UBR4 FBXO11

1.08e-0371322785
GeneFamilyMyosins, class I

MYO1G MYO1B

1.44e-03813221097
GeneFamilyBEN domain containing

BEND2 BEND7

1.84e-0391322422
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

DOCK1 USP34 NCOA3 KAT6A NEK7 APC ARFGEF1 MYO1B XPO1 MBOAT2 SNX13 EFR3A TGIF1 BPTF TLK1 MITF USP7 KIF14 MACF1 PRMT3 MAPK6 KAT6B SMAD7

1.87e-0885617723M4500
CoexpressionSHEN_SMARCA2_TARGETS_UP

ERCC3 NEK7 APC PON2 RIOK3 FBXO11 IDE XPO1 ACTR3 TLK1 MACF1 CTNNA1 CAMSAP1 REV1

1.43e-0642917714M29
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

MYO9A SMC6 THUMPD3 APC ARFGEF1 XPO1 RFC1 SNX13 BPTF MITF KIF14 SLC45A2 CDC5L MAPK6 CSPP1 DYNC1I1 SORL1

2.46e-0665617717M18979
CoexpressionDAZARD_RESPONSE_TO_UV_NHEK_DN

NCOA3 KAT6A XPO1 BPTF TLK1 MTMR6 FAT2 NFE2L2 KIF14 KAT6B SMAD7

6.67e-0630017711M8702
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

NCOA3 KAT6A NEK7 ARFGEF1 MYO1B XPO1 SNX13 BPTF TLK1 KIF14 PRMT3 MAPK6 KAT6B

1.83e-0546617713M13522
CoexpressionENK_UV_RESPONSE_KERATINOCYTE_DN

NCOA3 ATP6V1A KAT6A ARFGEF1 XPO1 ACTR3 STT3A BPTF FAT2 USP7 MACF1 CTNNA1 SORL1

2.55e-0548117713M3898
CoexpressionACEVEDO_METHYLATED_IN_LIVER_CANCER_DN

GALNT14 NRAP MYO9A OLFML2B TM9SF3 KAT6A AGPAT4 SLCO3A1 DGKG CPN1 CCDC141 MBOAT2 TENM2 HOXA6 ZNF462 FAT2 CSPP1 RASD2

2.77e-0587317718M16009
CoexpressionWONG_ADULT_TISSUE_STEM_MODULE

MYLK PCLO NIPSNAP1 SLCO3A1 DGKG MYO1B ACTR3B CR2 TENM2 MITF MACF1 PYGM TBX1 PHLDB2 SMAD7 SORL1

3.31e-0572117716M1999
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

AFF2 MYLK OLFML2B SYT17 SLCO3A1 MYO1B OTOGL KCNS3 LRRC8B

1.19e-072001789bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

ATP6V1A RIOK3 FAT2 SERPINB13 NFE2L2 MAPK6 CAMSAP1 REV1

5.42e-0717517880cc215109d9915af47e4d0a120ce2e46910715fa
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AFF2 OLFML2B SYT17 SLCO3A1 DGKG PAPLN MYO1B KCNS3

7.60e-0718317888a799807fbf24456a9811e0c64068187940a2f71
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-smooth_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK SLCO3A1 DGKG MYO1B CCDC141 OTOGL KLHL23 TBX10

1.05e-061911788ff7874cc005760a8f3b2e8072fbe418b6bfacaa8
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SPEF2 TTC21A DNAH7 RSPH10B2 PAX7 CFAP57 DNAH6 CSPP1

1.13e-061931788ea345d34440b25f65358a53dc72831998d1c3620
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

AFF2 MYLK OLFML2B SYT17 DGKG MYO1B KCNS3 CSPP1

1.48e-062001788786f1ae53e60b5ffbf4bfd393d10b802478148b3
ToppCellParenchymal-10x5prime-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

AFF2 MYLK OLFML2B DGKG MYO1B NT5DC2 KLHL23 RASD2

1.48e-062001788f9bc22ff17bb1c751e6b05bca3f403836f33459a
ToppCellParenchymal-10x5prime-Stromal-Pericyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

AFF2 MYLK OLFML2B DGKG MYO1B NT5DC2 KLHL23 RASD2

1.48e-0620017880a7640db28c708003d5da2d19eb651f6fedfd710
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS6KA5 NIPSNAP1 PLEK2 AASS NQO1 TBX1 NOS1AP

3.33e-061571787a426c54fd1545093d41426e9620862f71bd06f6b
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPEF2 TTC21A DNAH7 SLC45A2 CFAP57 DNAH6 CSPP1

5.42e-06169178714aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellIonocyte-iono-2|World / Class top

GALNT14 ATP6V1A MBOAT2 KCNS3 ATP6V0D2 UNC13A SLC27A2

6.32e-061731787e5ec28ccc5e048fd98de4c876e5c53b866b66228
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HYAL4 ATP6V1A SYT17 HCN2 PLEK2 PTPRJ ATP6V0D2

7.33e-0617717878e4005fad50e6f919da175f3b9ae58849dbd60b1
ToppCellfacs-Heart-RV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK1 MYLK SLCO3A1 MYO1B MAGEB16 KLHL23 UNC13A

7.33e-0617717877c3d46ebd7e8726be6871aa9763e281fc0ec6ac8
ToppCellfacs-Heart-RV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK1 MYLK SLCO3A1 MYO1B MAGEB16 KLHL23 UNC13A

7.33e-061771787e7b1f3092e6b8d0d580f82648035f5ad12be6961
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HYAL4 ATP6V1A SYT17 PLEK2 PTPRJ HABP2 ATP6V0D2

7.89e-06179178727ad6a609fe1f7532b142d0147bccf918704a6dd
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK1 NRAP MYLK DGKG TENM2 PHKG1 PYGM

9.12e-0618317876f5dbac2748f50105f0f548d189c42ef14287019
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AFF2 OLFML2B SYT17 DGKG PAPLN MYO1B KCNS3

9.45e-061841787689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA11 TTC21A ZSWIM2 CFAP57 PLEKHA7 DNAH6 CSPP1

9.45e-061841787264e14aa1859cfc0ed5fb40e97ea189aed9ef4a5
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AFF2 MYLK OLFML2B SYT17 DGKG PAPLN KCNS3

9.45e-061841787102b6f621a5b551e622f97b12d787c080b052a72
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA11 TTC21A ZSWIM2 CFAP57 PLEKHA7 DNAH6 CSPP1

9.45e-061841787d7eccbd21c480d907fdc8eff2bf5ae22ae452221
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA11 TTC21A ZSWIM2 CFAP57 PLEKHA7 DNAH6 CSPP1

9.45e-06184178722010cfe0428ebfa40952cc1a1a12ad3d25b35c9
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ERCC3 MYO9A AGPAT4 IDE ENPP4 P3H1 MAPK6

9.78e-0618517877925519b855f76444a0b57382ce35d89457b0b14
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CCDC168|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK1 ITGA11 B3GLCT MYLK CSMD2 PHLDB2 RASD2

9.78e-0618517875a0340c25196453f19e424d346efbf66d2c53ac3
ToppCellCOPD-Stromal-Pericyte|World / Disease state, Lineage and Cell class

AFF2 MYLK DGKG MYO1B TJP1 AASS KLHL23

1.01e-0518617878adfd2d1fda4e8aecc95192ea627bf7ed5214b8d
ToppCellSubstantia_nigra-Neuronal|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PCLO TENM2 DLG4 LRRC7 UNC13A DYNC1I1 NOS1AP

1.01e-0518617873f889083fcffe516388e9b03a5e23af2010ced33
ToppCelldroplet-Marrow-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFF2 OLFML2B MCM5 RFC1 HPF1 KLHL23 REV1

1.05e-05187178714c239af77116d28d511dea754b6150d20488080
ToppCell15-Distal-Mesenchymal-Pericyte|Distal / Age, Tissue, Lineage and Cell class

OLFML2B SLCO3A1 DGKG MYO1B KLHL23 PYGM KCNS3

1.09e-0518817874963382e54aac06bf5047c7d725393db70667ee7
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCSK1 GALNT14 MYLK DGKG KLHL23 PYGM RASD2

1.09e-051881787a5e7a363fbd5ae4d9312cf6f9941413d6a5c0b4d
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TM9SF3 KAT6A NEK7 STT3A SNX13 MTMR6 MACF1

1.12e-051891787875df61ee48baa5142ba4d2427bdec1c53e5a828
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)-D175|Adult / Lineage, Cell type, age group and donor

ATP6V1A XPO1 EHBP1L1 PTPRJ MITF ATP6V0D2 CAMSAP1

1.25e-051921787733491e932350e3c216a626cc49c3cd3fe970a82
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT14 MYO9A PCLO DNAH7 PTPRJ MITF PLEKHA7

1.33e-05194178793c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPEF2 TTC21A DNAH7 NQO1 CFAP57 DNAH6 CSPP1

1.38e-051951787649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT14 MYO9A PCLO DNAH7 PTPRJ PLEKHA7 NOS1AP

1.38e-0519517876477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPEF2 TTC21A DNAH7 NQO1 CFAP57 DNAH6 CSPP1

1.38e-051951787129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPEF2 TTC21A DNAH7 NQO1 CFAP57 DNAH6 CSPP1

1.38e-0519517873e70ee987d66d450062d5df3d7c733ccc7344470
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT14 MYO9A PCLO DNAH7 PTPRJ MITF PLEKHA7

1.42e-0519617876ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT14 MYO9A PCLO DNAH7 PTPRJ MITF PLEKHA7

1.42e-051961787eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Pericyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

OLFML2B PON2 DGKG MYO1B TJP1 NT5DC2 KCNS3

1.47e-05197178744cd1ece3633a31e8c9b667cd3cbc2749c06f478
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NRAP SPEF2 TTC21A PAPLN DNAH7 HABP2 DNAH6

1.47e-0519717876e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Pericyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

AFF2 OLFML2B DGKG MYO1B TJP1 NT5DC2 KCNS3

1.52e-05198178776d46950c11cb4708866db0da54ce00d5c0adab8
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

PCLO SMC6 ARFGEF1 RFC1 BPTF NQO1 ANKRD11

1.57e-051991787c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

AFF2 MYLK OLFML2B DGKG MYO1B TENM2 KCNS3

1.62e-052001787b5b5a32925f225610fe25a021a742d6397162863
ToppCellParenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

AFF2 MYLK OLFML2B DGKG MYO1B NT5DC2 KLHL23

1.62e-0520017870c648941447c738caf62f2d71e296d6cca492c8b
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

AFF2 MYLK OLFML2B SYT17 DGKG MYO1B KCNS3

1.62e-052001787d2fcd3bd7c3223875f027eeb48ff621192a5f242
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

AFF2 MYLK OLFML2B DGKG MYO1B TENM2 KCNS3

1.62e-052001787b22cae282591d8dead9869c2adbb9632615f50f7
ToppCellTracheal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

AFF2 MYLK OLFML2B DGKG MYO1B OTOGL KLHL23

1.62e-0520017878158f4eaeff945a6788c8e732b7a1b0d78052a06
ToppCell(09)_Interm._secr.>cil.|World / shred by cell type by condition

SPEF2 DNAH7 RSPH10B2 CFAP57 DNAH6 CSPP1 RSPH10B

1.62e-0520017873305e14dba12e94da42f0414fdc7a2c8caf0a183
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AFF2 MYLK OLFML2B DGKG MYO1B NT5DC2 KLHL23

1.62e-052001787522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCellTracheal-10x3prime_v2-Stromal-Pericyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

AFF2 MYLK OLFML2B DGKG MYO1B OTOGL KLHL23

1.62e-052001787600d56257b1b0cda8ed2fd0db92c6551711f7d6d
ToppCellBronchial-10x5prime-Stromal-Pericyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

AFF2 MYLK DGKG MYO1B NT5DC2 KLHL23 RASD2

1.62e-052001787362706445edb33b313684efe50b1f44f5f816e67
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

AFF2 MYLK OLFML2B DGKG MYO1B NT5DC2 KLHL23

1.62e-05200178794f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte|Control_saline / Treatment groups by lineage, cell group, cell type

AFF2 MYLK OLFML2B DGKG MYO1B TENM2 KCNS3

1.62e-052001787cb7ef774b6d300f8019c5b16a04e3ebd165e4f1c
ToppCellfacs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZSWIM2 PLEK2 CCNB3 OTOGL LRRC7 PAX7

2.22e-0514117864aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCellfacs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZSWIM2 PLEK2 CCNB3 OTOGL LRRC7 PAX7

2.22e-051411786e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCellControl-Epithelial_alveolar-AT_1-AT2_Progenitor|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PAPLN CR2 TIGD5 TBX1 SLC27A2 RASD2

2.31e-05142178694e277f038f4006d99ff50222b0f5cf89bc3d46d
ToppCellfacs-Heart-Unknown-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZSWIM2 PLEK2 CCNB3 OTOGL LRRC7 PAX7

2.31e-051421786759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ATP6V1A SYT17 ESRP1 PTPRJ NFE2L2 ATP6V0D2

3.15e-05150178687968ce885a4959616f0321f58517fe8029ba1b1
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HYAL4 ATP6V1A SYT17 PLEK2 PTPRJ ATP6V0D2

4.51e-051601786174a4ab27114efcc63be36929b80680be3c35c9b
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PIGB SLC25A42 NADK2 TFR2 AATK TIGD5

4.51e-0516017868374ae912337947b2cc8d17d5840f306361fe1ff
ToppCellBAL-Mild-cDC_5|Mild / Compartment, Disease Groups and Clusters

SLC25A42 IFT172 RSPH10B2 PHKG1 AATK DCLK2

4.67e-0516117867a6e8ed0b5d999efce8945d8083ab01d71be9a92
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PON2 RSPH10B2 PHKG1 CD1C AATK DCLK2

4.67e-05161178678cc5bc488bc47726195a649946d414e6bfabf94
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PON2 RSPH10B2 PHKG1 CD1C AATK DCLK2

4.84e-0516217860fa93efc9c005d1e649b3f7069ae8641d6e41ed8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HYAL4 ATP6V1A SYT17 PTPRJ GNA11 ATP6V0D2

5.18e-05164178683141be8dfed85511ea6afda7c76ff4b6b5ef021
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PCLO PLEK2 SERPINB13 IL20 NT5DC2 SLC45A2

5.54e-0516617869fd9de82f98b9acdaa59ac98fb9664161514aec0
ToppCellfacs-Tongue-nan-3m-Epithelial-basal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYT17 COLGALT2 TGIF1 IL20 BEND7 LRRC8B

5.92e-051681786ca0c4a819f9047fc40d224f7656fec60f6fa05d8
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPEF2 TTC21A DNAH7 CFAP57 DNAH6 RSPH10B

6.12e-051691786fba841664939c771881ba97f14ef1df6635c04ff
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HYAL4 ATP6V1A SYT17 PLEK2 PTPRJ ATP6V0D2

6.12e-0516917864b3a7b4a497178799b6b2f0b744f5fb752cee31a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HYAL4 ATP6V1A SYT17 PLEK2 PTPRJ ATP6V0D2

6.12e-051691786a4fd646b9bf87225131fca530bd6b52df9eaf489
ToppCellE16.5-samps-Epithelial-Alveolar_epithelial_precursor-Uncommitted_AE_cell|E16.5-samps / Age Group, Lineage, Cell class and subclass

NIPSNAP1 PLEK2 HABP2 FLRT3 MAPK6 PLEKHA7

6.32e-0517017865a64e05c263df915085988d881808221e2c0f2e2
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO3A1 MYO1B VSX1 FMO6P CCNB3 KCNS3

6.32e-05170178617bd7fd25a2657cb536ad47e294332920f759e95
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OLFML2B SYT17 SMC6 PAPLN OTOGL KCNS3

6.32e-0517017865570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9|TCGA-Bladder / Sample_Type by Project: Shred V9

NCOA3 SLCO3A1 FAT2 SERPINB13 NFE2L2 MAPK6

6.53e-051711786adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO NQO1 FLRT3 PLEKHA7 DNAH6 TBX1

7.42e-051751786f6e1d7297a4dbb38e1ab4f738d91f0e62abaee69
ToppCell3'-Adult-Appendix-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ACTR3B LCT CR2 ACTR3 DCLK2 DAGLA

7.66e-05176178630adf8f1638c6244586f8101c2590bb964dfae00
ToppCell3'-Adult-Appendix-Epithelial-mature_enterocytic-Colonocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ACTR3B LCT CR2 ACTR3 DCLK2 DAGLA

7.66e-05176178623fa02d4c39e0b8faa1658116d50b6233a952ccc
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AFF2 MYLK OLFML2B DGKG MYO1B NT5DC2

7.90e-051771786452ec2df36c6d656a7cdadc55be545ccdb146a29
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 AFF2 DGKG MYO1B COLGALT2 DYNC1I1

7.90e-051771786a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 AFF2 DGKG MYO1B COLGALT2 DYNC1I1

7.90e-0517717863645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK DGKG MYO1B CPN1 CR2 CFAP57

8.15e-0517817867467e5ab2fcb39cc4a2c7dd69722c91def3b6aea
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HYAL4 ATP6V1A SYT17 PLEK2 GNA11 ATP6V0D2

8.15e-051781786f1cfc348d51362eb8c92c625f21f682afc0352b7
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPEF2 TTC21A DNAH7 NQO1 CFAP57 DNAH6

8.15e-0517817863b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAX TFR2 GXYLT2 KLHL23 KAT6B CDK6

8.40e-051791786e880c507f11ce75d104593a4ca29f0295f8125e8
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AFF2 MYLK DGKG HOXA6 OTOGL NT5DC2

8.40e-051791786dc6cd46fa652b296ddbc41855f6377946d0a4cdc
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC25A42 PCLO OTOGL LRRC7 FUT6 SLC27A2

8.66e-051801786f8bdfd7bf7b3d52c659a29d8f5f80858e79da83e
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NRAP SYT17 ACTR3B TFR2 NT5DC2 KCNS3

8.93e-051811786ebf1ae963a2b22e1772752ed85a4fb0e546d377e
ToppCelldroplet-Lung-nan-3m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESRP1 CPN1 CCDC141 AASS FLRT3 RASD2

9.21e-051821786cfba75c1ffc39ac76db9e8e27394731942882b30
ToppCelldroplet-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESRP1 CPN1 CCDC141 AASS FLRT3 RASD2

9.21e-051821786d836bfdc298ecd3558a973e393a329eb8bd59d79
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNT14 ITGA11 OLFML2B MBOAT2 OTOGL DNAH6

9.21e-051821786205d9ad1ea4b7adee8054496cdde46c9c401a19a
ToppCelldroplet-Lung-nan-3m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESRP1 CPN1 CCDC141 AASS FLRT3 RASD2

9.21e-0518217867e7c7a26460d3003cdf0c0ffb96208a566aa09a7
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ALX3 MYLK DGKG OTOGL KCNS3 PHLDB2

9.78e-05184178689ae8bf1a6c2d355d279d23a5e24a08d9ec2334e
ToppCellCOPD-Stromal-Pericyte|COPD / Disease state, Lineage and Cell class

AFF2 MYLK OLFML2B MYO1B AASS KLHL23

9.78e-051841786a56264a22dfc2d3672b20134ab7c3c7c23da5ae1
ToppCellfacs-Heart-RV-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK MYO1B CCDC141 AATK KLHL23 SORL1

9.78e-0518417869c20b50f8d6ac689d41d5440c835f9db8d04758b
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CACNG5|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

B3GLCT CSMD2 TENM2 ZNF462 FLRT3 TBX1

9.78e-051841786658f2e522055e88c92bc482a845c40f8f5f1a8e3
ToppCellfacs-Heart-RV-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK MYO1B CCDC141 AATK KLHL23 SORL1

9.78e-05184178631dbe6119a3bcd266ae5e9b340c853d9ff680dce
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ALX3 MYLK DGKG OTOGL KCNS3 PHLDB2

9.78e-05184178634c84ac9a32eaf96f45b79485119cad65905817d
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

XPO1 ENPP4 KIF14 MACF1 SLC27A2 CDK6

1.01e-041851786a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage-stroma-osteoclast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ATP6V1A MYO1B ZNF462 MITF SLC45A2 ATP6V0D2

1.01e-0418517865ed49b6d8214c6119355a6d3ee4e25d40bcc0c53
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 PON2 PAPLN AASS PYGM PLEKHA7

1.07e-041871786dd1d91f101b837bba513f77defa6e6902b2c0570
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

AFF2 OLFML2B DGKG MYO1B TJP1 KLHL23

1.07e-041871786fa01a61bfd13feb033ba1e35cf513707b1bff8c8
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

AFF2 DGKG TJP1 OTOGL NT5DC2 KLHL23

1.07e-04187178686250acf088ec0c4800a0dfa031b0d4f7e52c342
DiseaseParoxysmal atrial fibrillation

USP34 XPO1 ZNF462 GTF2I PHLDB2 SMAD7 SORL1 CDK6

4.48e-061561758C0235480
Diseasefamilial atrial fibrillation

USP34 XPO1 ZNF462 GTF2I PHLDB2 SMAD7 SORL1 CDK6

4.48e-061561758C3468561
DiseasePersistent atrial fibrillation

USP34 XPO1 ZNF462 GTF2I PHLDB2 SMAD7 SORL1 CDK6

4.48e-061561758C2585653
DiseaseAtrial Fibrillation

USP34 XPO1 ZNF462 GTF2I PHLDB2 SMAD7 SORL1 CDK6

5.41e-061601758C0004238
DiseaseQRS duration

USP34 OLFML2B UBR4 XPO1 CCDC141 PTPRJ MITF DYNC1I1 NOS1AP CDK6

1.25e-0529817510EFO_0005055
DiseaseMainzer-Saldino Disease

IFT140 IFT172

3.50e-0521752C1849437
Diseaseneutrophil count

MYO1G OLFML2B NEK7 DGKG RIOK3 MYO1B XPO1 LCT SNX13 TGIF1 CD1C TRAP1 AATK LRRC25 PTPRJ BEND7 MITF ANKRD11 ATP6V0D2 NOS1AP CDK6

7.56e-05138217521EFO_0004833
DiseasePtosis

ZNF462 PAX7

1.05e-0431752C0033377
DiseaseBlepharoptosis

ZNF462 PAX7

1.05e-0431752C0005745
DiseaseC-reactive protein measurement

PCSK1 USP34 OLFML2B IFT172 BAAT THUMPD3 NEK7 ZNF226 BPTF TLK1 GTF2I LRRC25 NFE2L2 MACF1 SHE DLG4 CTNNA1 MAPK6 DAGLA

1.06e-04120617519EFO_0004458
Diseaseeotaxin measurement

OLFML2B RAX TBC1D22A HABP2 NOS1AP

1.16e-04801755EFO_0008122
Diseasealkaline phosphatase measurement

USP34 RPS6KA5 NEK7 PAPLN MYO1B VSX1 PLEKHM1 SNX13 TGIF1 TLK1 PTPRJ MITF MACF1 DLG4 CDC5L FUT6 SMAD7

1.21e-04101517517EFO_0004533
Diseasealcohol consumption measurement

DOCK1 RPS6KA5 IFT172 PCLO ZSWIM2 RIOK3 FBXO11 PAPLN RFC1 MBOAT2 TENM2 LRRC25 PTPRJ NFE2L2 NQO1 ANKRD11 CTNNA1 MAPK6 SORL1

1.55e-04124217519EFO_0007878
DiseaseDiGeorge syndrome (implicated_via_orthology)

DOCK1 KAT6A TBX1

1.85e-04191753DOID:11198 (implicated_via_orthology)
DiseaseAlzheimer's disease biomarker measurement

AGPAT4 MCM5 SORL1 RASD2

1.90e-04481754EFO_0006514
DiseaseOrofacial cleft, alcohol consumption measurement

SLCO3A1 PAX7

2.08e-0441752EFO_0007878, HP_0000202
Diseaserosacea severity measurement

LINC01619 PCLO EHBP1L1 SLC45A2 DCLK2 ATP6V0D2

2.53e-041471756EFO_0009180
Diseaseotitis media (implicated_via_orthology)

FBXO11 TGIF1 TBX1

2.91e-04221753DOID:10754 (implicated_via_orthology)
Diseasefamilial long QT syndrome

OLFML2B NOS1AP

3.46e-0451752MONDO_0019171
Diseasetotal blood protein measurement

NCOA3 RIOK3 XPO1 SNX13 TLK1 EHBP1L1 MACF1 LRRC8B ATP6V0D2 CDK6

3.70e-0444917510EFO_0004536
Diseasecortical surface area measurement

ALX3 USP34 ITGA11 APC XPO1 DNAH7 TENM2 PLEKHM1 SNX13 TJP1 TBC1D22A NT5DC2 MACF1 KCNS3 PAX7 CDC5L MAPK6 PLEKHA7 CDK6

4.21e-04134517519EFO_0010736
DiseaseHereditary Nonpolyposis Colorectal Neoplasms

APC PTPRJ CTNNA1

4.82e-04261753C0009405
Diseasemyeloid white cell count

MYO1G USP34 DGKG RIOK3 MYO1B XPO1 LCT SNX13 TRAP1 LRRC25 PTPRJ BEND7 ATP6V0D2 SORL1 CDK6

4.92e-0493717515EFO_0007988
DiseaseHereditary Nonpolyposis Colorectal Cancer

APC PTPRJ CTNNA1

6.69e-04291753C1333990
Diseasefocal segmental glomerulosclerosis (implicated_via_orthology)

MYO9A ACTR3

7.20e-0471752DOID:1312 (implicated_via_orthology)
DiseaseAlbinism, Oculocutaneous

MITF SLC45A2

7.20e-0471752C0078918
Diseaseglypican-1 measurement

NRAP HABP2

7.20e-0471752EFO_0801649
Diseasemelanoma

ERCC3 UBR4 MYO1B RAX MITF SLC45A2 GNA11

7.27e-042481757C0025202
DiseaseWilliams Syndrome

GTF2I DLG4

9.57e-0481752C0175702
Diseaseneonatal abstinence syndrome

DOCK1 SNX13 SLC27A2 NOS1AP

1.15e-03771754EFO_0005799
Disease3-hydroxy-1-methylpropylmercapturic acid measurement

DOCK1 USP34 SYT17 SPEF2 SLCO3A1 BEND2 PTPRJ PRMT3

1.25e-033521758EFO_0007015
Diseaselongitudinal BMI measurement

DOCK1 PCSK1 KCNS3 NOS1AP

1.46e-03821754EFO_0005937
DiseaseIntellectual Disability

PIGB APC STT3A ZNF462 BPTF AASS ALG14 MACF1 DLG4

1.46e-034471759C3714756
Diseaselung non-small cell carcinoma (is_implicated_in)

ERCC3 FBXO11 XPO1 NQO1 CDK6

1.47e-031391755DOID:3908 (is_implicated_in)
DiseaseHVA measurement, MHPG measurement

B3GLCT MYO9A CSMD2

1.72e-03401753EFO_0005131, EFO_0005133
Diseaseatrial fibrillation

USP34 XPO1 ZNF462 GTF2I PHLDB2 SMAD7 SORL1 CDK6

1.75e-033711758EFO_0000275
Diseaseneutrophil count, eosinophil count

MYO1G XPO1 TRAP1 LRRC25 PTPRJ CDK6

1.76e-032131756EFO_0004833, EFO_0004842
DiseaseCutaneous Melanoma

ERCC3 MITF GNA11

1.85e-03411753C0151779
DiseaseFamilial Atypical Mole Melanoma Syndrome

ACD MITF

1.86e-03111752C2314896
DiseaseJeune thoracic dystrophy

IFT140 IFT172

1.86e-03111752C0265275
Diseasecolon cancer (implicated_via_orthology)

APC NQO1

1.86e-03111752DOID:219 (implicated_via_orthology)
DiseaseChildhood Medulloblastoma

KAT6A APC CDK6

2.13e-03431753C0278510
DiseaseMelanotic medulloblastoma

KAT6A APC CDK6

2.13e-03431753C1275668
DiseaseMedullomyoblastoma

KAT6A APC CDK6

2.13e-03431753C0205833
DiseaseDesmoplastic Medulloblastoma

KAT6A APC CDK6

2.13e-03431753C0751291
DiseaseAdult Medulloblastoma

KAT6A APC CDK6

2.13e-03431753C0278876
DiseaseGastrointestinal Diseases

MYLK NFE2L2

2.22e-03121752C0017178
Diseaselevel of C-X-C motif chemokine 2 in blood serum

OLFML2B NOS1AP

2.22e-03121752OBA_2041207
DiseaseFunctional Gastrointestinal Disorders

MYLK NFE2L2

2.22e-03121752C0559031
DiseaseCholera Infantum

MYLK NFE2L2

2.22e-03121752C1565321
Diseasephenylacetylglutamine measurement

B3GLCT LRRC8B

2.22e-03121752EFO_0021013
Diseasegallbladder carcinoma (is_marker_for)

ACTR3 TJP1

2.22e-03121752DOID:4948 (is_marker_for)
DiseaseNon-Small Cell Lung Carcinoma

NCOA3 APC ZNF462 NFE2L2 NQO1

2.43e-031561755C0007131
Diseaseosteoarthritis, knee

NT5DC2 DCLK2 PAX7 MAPK6 DYNC1I1

2.57e-031581755EFO_0004616
Diseasemood disorder

FLRT3 SORL1

2.61e-03131752EFO_0004247
Diseaseliver cirrhosis (implicated_via_orthology)

NFE2L2 NQO1

2.61e-03131752DOID:5082 (implicated_via_orthology)
DiseaseShort Rib-Polydactyly Syndrome

IFT140 IFT172

2.61e-03131752C0036996
Diseaserespiratory quotient

AATK UNC13A

3.04e-03141752EFO_0005189
Diseasechromosome 22q11.2 deletion syndrome, distal (implicated_via_orthology)

TBX10 TBX1

3.04e-03141752DOID:0060413 (implicated_via_orthology)
DiseaseSaldino-Noonan Syndrome

IFT140 IFT172

3.04e-03141752C0036069
DiseaseMajewski Syndrome

IFT140 IFT172

3.04e-03141752C0024507
Diseasepulmonary emphysema (is_marker_for)

NFE2L2 NQO1

3.04e-03141752DOID:9675 (is_marker_for)
DiseaseT wave morphology measurement

OLFML2B NOS1AP

3.04e-03141752EFO_0008398
Diseasebasophil count, eosinophil count

LINC01619 SPEF2 XPO1 BPTF SERPINB13 CDK6

3.25e-032411756EFO_0004842, EFO_0005090
DiseaseMedulloblastoma

KAT6A APC CDK6

3.28e-03501753C0025149
DiseaseQRS amplitude, QRS complex

OLFML2B MITF NOS1AP

3.28e-03501753EFO_0005054, EFO_0007742
DiseaseWilliams-Beuren syndrome (implicated_via_orthology)

GTF2I DLG4

3.49e-03151752DOID:1928 (implicated_via_orthology)
Diseaselevel of C-X-C motif chemokine 3 in blood serum

OLFML2B NOS1AP

3.49e-03151752OBA_2041208
Diseasepancreatic adenocarcinoma (is_implicated_in)

SMAD7 CDK6

3.49e-03151752DOID:4074 (is_implicated_in)
Diseasefacial width measurement

SPEF2 PCLO HABP2 DYNC1I1

3.59e-031051754EFO_0007855
DiseaseSchizoaffective disorder-bipolar type

MYO1G PCLO

3.97e-03161752EFO_0009965
DiseaseHepatomegaly

MYO1B MBOAT2 NFE2L2

4.07e-03541753C0019209
Diseasegranulocyte count

MYO1G XPO1 TRAP1 LRRC25 PTPRJ CDK6

4.19e-032541756EFO_0007987
DiseaseCholestasis

BAAT NFE2L2 NQO1 SORL1

4.24e-031101754C0008370
DiseaseEye Abnormalities

APC VSX1

4.49e-03171752C0015393
DiseaseMalignant neoplasm of breast

NCOA3 TPTE ERCC3 UBR4 SMC6 DGKG COLGALT2 OTOGL BEND7 NQO1 MACF1 LRRC7 KAT6B SORL1

4.96e-03107417514C0006142
Diseaseirritable bowel syndrome symptom measurement

ACTR3B SNX13 CDK6

4.98e-03581753EFO_0021536
DiseaseMeckel syndrome type 1

KIF14 CSPP1

5.03e-03181752C3714506
DiseaseIdiopathic hypogonadotropic hypogonadism

CCDC141 FLRT3

5.03e-03181752C0342384
Diseaseheart failure

LINC01619 CCDC141 BPTF GTF2I CDK6

5.03e-031851755EFO_0003144
DiseasePolydactyly

ALX3 IFT140 IFT172 CSPP1

5.27e-031171754C0152427
Diseaseatrophic macular degeneration, age-related macular degeneration, wet macular degeneration

B3GLCT SPEF2 FUT6

5.48e-03601753EFO_0001365, EFO_0004683, EFO_1001492
Diseasemacula measurement

MYO9A RAX2 BPTF PLEKHA7 SORL1

5.50e-031891755EFO_0008375
DiseaseCongenital Myasthenic Syndromes, Presynaptic

MYO9A ALG14

5.60e-03191752C0751884
Diseaseskin sensitivity to sun

ANKRD11 SLC45A2

5.60e-03191752EFO_0004795
Diseaseacute lymphoblastic leukemia, response to antineoplastic agent

NCOA3 PRMT3

5.60e-03191752EFO_0000220, GO_0097327
DiseaseHereditary Non-Polyposis Colon Cancer Type 2

PTPRJ CTNNA1

5.60e-03191752C1333991
Diseaseabnormal paneth cell measurement

SPEF2 ACTR3B

5.60e-03191752EFO_0007963
DiseaseColorectal cancer, hereditary nonpolyposis, type 1

PTPRJ CTNNA1

5.60e-03191752C2936783
Diseaseacute kidney failure (biomarker_via_orthology)

NFE2L2 NQO1 TBX1

5.74e-03611753DOID:3021 (biomarker_via_orthology)
Diseasecolorectal cancer (is_implicated_in)

APC XPO1 PTPRJ SMAD7

5.93e-031211754DOID:9256 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
HELYSREYQTDPAKK

UNC13A

1016

Q9UPW8
PVNRKYEYLDHTADV

ZBTB8OS

26

Q8IWT0
FASLALAYHNYEDLP

BAAT

186

Q14032
EHITYLEHNPYEKFS

CDC5L

611

Q99459
EAHLTEDQIFYFPKY

C8G

171

P07360
AIEPYHSDRANPYFE

ANKRD11

2426

Q6UB99
FHQARPVDYPKDYLS

B3GLCT

441

Q6Y288
RPGFKLEYQDLTYSH

CSMD2

2066

Q7Z408
VFQKTHYPDVYAREQ

ALX3

171

O95076
ISDNRFKAHASFYYP

ARFGEF1

1791

Q9Y6D6
PKLTFDDSVHNADYY

AFF2

1061

P51816
VVFKYLRAEPEDHYF

ACTR3B

96

Q9P1U1
ALHPEQKADRYFVLY

ASCC2

26

Q9H1I8
ERIYLYHNSLDEFPT

FLRT3

86

Q9NZU0
ILQLDEVDFYYDPKH

ABCF3

491

Q9NUQ8
EVDFYYDPKHVIFSR

ABCF3

496

Q9NUQ8
PAEYDKHPERYISRF

AASS

281

Q9UDR5
AYSALSHPYFQDLER

CDK6

291

Q00534
NAYSPRHYVIADTDE

ALG14

61

Q96F25
SDKEYHHVLPYQEAE

BPTF

336

Q12830
RDPFYVDQYEQEHIK

CAMSAP1

61

Q5T5Y3
SFADHVVPLLEYYRD

CDAN1

701

Q8IWY9
FANIEEDTPSYHRRY

EFR3A

126

Q14156
KFEEHNSPRVDDFVY

CCNB3

1216

Q8WWL7
YNHRFSDPERVNYKF

ESRP1

196

Q6NXG1
QLERAFEASHYPDVY

RAX2

41

Q96IS3
YPDVYSREELAAKVH

RAX2

51

Q96IS3
PHLEAALQEYFVAYE

P3H1

226

Q32P28
VENHYKLSLPEDFYH

HPF1

41

Q9NWY4
PLDHESYEFKVISQY

PARP2

371

Q9UGN5
ELEKAFERTHYPDIY

PAX7

231

P23759
FLDHKTLYYDVEPFL

KAT6B

811

Q8WYB5
ERDKFFQSHYTYNPQ

KIAA0895L

151

Q68EN5
AYHIYHEEFQKRSPS

RSPH10B

501

P0C881
AYHIYHEEFQKRSPS

RSPH10B2

501

B2RC85
EHPDTKQVYNFIYDV

KIF14

391

Q15058
HPSADVLKYTYEDFK

PTPRJ

861

Q12913
PDHEYKFRVRAINVY

MYLK

1396

Q15746
DYLHFSPEQQYKPDS

HOXA6

101

P31267
YPHSFPSQYAEALKE

MAGEB16

301

A2A368
EVDPIRHYYAFFSKL

MAGEB18

166

Q96M61
FFDDDYDYLQHLKEP

LTV1

61

Q96GA3
RHYFIEPSQLKLFYD

MBOAT2

401

Q6ZWT7
DEDLADYLYKQPAEH

MCM5

81

P33992
ADYKHDIVDYNYPAT

NRAP

446

Q86VF7
YRTQYHKFTALPEDL

NRAP

1381

Q86VF7
FPVLSYYHQDKEAAI

MTMR6

186

Q9Y217
RYEDEHPSYQEVKAQ

LRRC7

1171

Q96NW7
VRYTHSFPEALQKFY

NADK2

196

Q4G0N4
HTGDPKQDLAYERQY

EIF3L

26

Q9Y262
AHPSEDNDFYINYKD

LRRC25

261

Q8N386
FKEYQEEAYSISLHP

CFAP57

426

Q96MR6
HLRRYSYNSEEVDFP

BEND2

141

Q8NDZ0
HNKPLYSFEDNADYV

DYNC1I1

521

O14576
PEKFRYAQDDFVLDH

DCLK2

271

Q8N568
TLPEDRFGYRDDHYQ

PCLO

2961

Q9Y6V0
KYSPEFQQHLYEAEL

FAT2

2476

Q9NYQ8
REKYLEDPAFDTNYS

MAPK6

406

Q16659
YNRKDGKPFDEHDEY

PDE6C

406

P51160
HPNVIKYYASFIEDN

NEK7

91

Q8TDX7
PEAKLTEVDNYHFYS

NFE2L2

216

Q16236
AYHNPDARTYEDKRA

CSPP1

701

Q1MSJ5
FRADYLKNYEFPHLQ

ENPP4

36

Q9Y6X5
YHDDKQPTFRALYEA

GXYLT2

366

A0PJZ3
LHRFYPDKIDYASLD

EHBP1L1

1076

Q8N3D4
YYEFVAALHPNKDAY

MACF1

3226

O94854
PNTEDTDRIFYHKTY

LCT

1281

P09848
SVADKEYYFDRNPSL

KCNS3

61

Q9BQ31
FRGNYLHSRDYKNPE

FMO6P

166

O60774
DSPFYQHYDLDLKDK

RPS6KA5

416

O75582
SHYEVKPNSSLERYD

ITGA11

966

Q9UKX5
DTSIDYNPLYKERHQ

DDX23

281

Q9BUQ8
HLADQYDPLYSKRFS

LRRC8B

371

Q6P9F7
FQYPAESVLAYKEGH

NQO1

66

P15559
AKELDPRYEDYVDQH

IFT172

1381

Q9UG01
DDPYKLYAFNQRESE

GALNT14

71

Q96FL9
NDHYFSDPFLKYLET

PON2

181

Q15165
LDHKTLYYDVEPFLF

KAT6A

601

Q92794
LKQYDPHEPISYDVF

DGKG

41

P49619
FKYSHYNERDEIPHN

HABP2

396

Q14520
VIFKYLRAEPEDHYF

ACTR3

96

P61158
AYPKYTFHDREEVVK

DNAH6

166

Q9C0G6
KFYDADDYHPEENRR

IDNK

31

Q5T6J7
QEDYIYLFKDSTHPV

KLHL23

6

Q8NBE8
VANYPYDKSFEHRVR

CPN1

221

P15169
EDFHYDYIDLLKEPA

CCDC141

1131

Q6ZP82
FHLEAREVYSVDPYN

CR2

1016

P20023
YEKAFFTDRYLQEHP

DOCK1

1541

Q14185
HPDVAAYKANRDLIY

CTNNA1

231

P35221
DHASQDYSKYPFEVQ

CD1C

101

P29017
ESYRDFIYQNPHIFK

PRMT3

241

O60678
EHFYSNPARYKGREN

FBXO11

251

Q86XK2
DKILYSHLVDYFPEF

GNA11

281

P29992
APTEHLRLYDKYDFL

DNAH7

486

Q8WXX0
HLEKADQDINYYIPA

HYAL4

121

Q2M3T9
RPYFTIHDSEFKEYT

DENND6A

326

Q8IWF6
KFYLAFENSLHPDYI

FUT6

241

P51993
QYKPEEYSRFEAKIH

DLG4

391

P78352
AVYETPFYVAVDHDK

DAGLA

376

Q9Y4D2
DYHHEVYKIPEFSND

BEND7

21

Q8N7W2
HENDERPFYQKTAPY

CSN3

31

P07498
LDRVFKNYQTPDHYT

IL20

91

Q9NYY1
YPKENEYSQFLSEHA

IDE

121

P14735
YFPLDEHVDHYSRTK

SDR42E2

166

A6NKP2
HLEYPLLAEYDFRND

ERCC3

286

P19447
DPIYRIFYVSHDSQD

NOS1AP

111

O75052
EASDKLTFYPPHQDY

COLGALT2

246

Q8IYK4
PYQKFEAHPNDLYVE

GTF2I

491

P78347
PYSAHNSTEFLIYER

SLC45A2

351

Q9UMX9
KLPADFRQKIHDYYE

HCN2

491

Q9UL51
LSYYEKSDTHRFEVP

IFT140

921

Q96RY7
SAERPNYFLYVHDND

OTOGL

1276

Q3ZCN5
QHEYAAPADYFRILV

NUP58

336

Q9BVL2
HSAQDFYENYEPKEI

PHKG1

11

Q16816
FHNVKPEYLDAYNSL

NIPSNAP1

76

Q9BPW8
HEYYQPTALLRDAEE

PLEKHM1

146

Q9Y4G2
KSHYLDEADVFYLNP

PIGB

466

Q92521
KASPALAHYVYDFLE

SNX13

671

Q9Y5W8
KHPFIQDLISNYSDY

SPEF2

1776

Q9C093
QFYHSPADNKRYIFA

SORL1

166

Q92673
PADNKRYIFADAYAQ

SORL1

171

Q92673
PEFLTHQYKYEAGEI

SLCO3A1

126

Q9UIG8
RTYNPDDYFRKFEPH

SYT17

146

Q9BSW7
DDYFRKFEPHLYSLD

SYT17

151

Q9BSW7
LNEKNPYRDSAYFSD

AATK

986

Q6ZMQ8
AFTRAYNKEAHLTPY

RFC1

1061

P35251
KLFQHIADYLPSYAR

SLC27A2

541

O14975
EAYLNGHAETPVYRF

NCOA3

321

Q9Y6Q9
LPSDYKYAQDRASHL

PLEKHA7

491

Q6IQ23
HIKENDYYTPTGEFR

STT3A

611

P46977
YDPLTKLVHFTQRDY

TENM2

2416

Q9NT68
VPYAAIQFSAHEEYK

SLC25A42

101

Q86VD7
AYAHPEYEERFLQEE

OLFML2B

236

Q68BL8
YPDHSYKDQAFDTLS

PHLDB2

991

Q86SQ0
YPKHEGIFSTLNRDY

SOX30

656

O94993
LERAFEKSHYPDVYS

RAX

151

Q9Y2V3
KRHRDGSAFQYEYEP

ACD

406

Q96AP0
YNEEKRHVDQPIDYS

APC

1166

P25054
YPLQVYQLHFESSDK

LINC01619

91

G3V211
ISFENYRKVHPYEDS

RIOK3

111

O14730
DFIPLDDKRYRYAFH

TBX10

116

O75333
HRYNAYPSEQEKALL

TGIF1

186

Q15583
AASYHRKKLEEYNAP

TRIM61

136

Q5EBN2
KAFSEAHYPDVYARE

VSX1

181

Q9NZR4
DHPRIVKLYDYFSLD

TLK1

516

Q9UKI8
VYNLCSERAYDPKHF

TPTE

281

P56180
KDFEEYPEHRTNFFL

XPO1

836

O14980
AFLHYYDPSKEENRP

PLEK2

276

Q9NYT0
YEKAYSLQRPNDHEF

SMAD7

371

O15105
EFHEEPKTYYELKSQ

MITF

16

O75030
FAAYLEREYKVHINP

PYGM

546

P11217
LQAVPYDFHAYKEVA

REV1

536

Q9UBZ9
NFYYKHREAVVDGTP

PAPLN

126

O95428
KYYHASLEPVDFVNA

SERPINB13

126

Q9UIV8
DQYTPTIEDFHRKVY

RASD2

46

Q96D21
IDDAYRQGHFTYKPV

SMC6

491

Q96SB8
LDEYYDKHFTEFVPL

ATP6V1A

461

P38606
YTLAQYADALHPEIF

NT5DC2

76

Q9H857
LPKQVADHYDNFRIY

MARS2

456

Q96GW9
KALEVYDEAYRQNPH

TTC21A

746

Q8NDW8
AYRLKFAFADAPNHY

TBC1D22A

501

Q8WUA7
AAYSIAYHSRPLNDF

ZNF862

561

O60290
DSHILDYYENPAIKE

THUMPD3

181

Q9BV44
DYKISQHFPRYLQDL

ZSWIM2

486

Q8NEG5
RVHKSEKSYRPNDYE

ZNF226

216

Q9NYT6
IRTHFEYEKESPYGL

TJP1

521

Q07157
DRFDKYLDPSFFQHR

TM9SF3

206

Q9HD45
HEEFYRYVAQAHDKP

TRAP1

311

Q12931
YFTAVYADEHEKPTL

ZNF462

1806

Q96JM2
KRPANEKATDDYHYE

C9orf78

266

Q9NZ63
ATSLQHLRDYPEKYF

AGPAT4

156

Q9NRZ5
FHVVYVDPRKDSEKY

TBX1

241

O43435
YSFIRDIVNPHAYKN

USP34

2166

Q70CQ2
PEIAHTYKADREKYN

UBE2D4

121

Q9Y2X8
HNQDKFPASYRYSPD

TIGD5

306

Q53EQ6
FDSIPEVVHYYSNEK

SHE

461

Q5VZ18
SEILHHEKQYEPFYS

UBR4

61

Q5T4S7
HEKQYEPFYSSFVAL

UBR4

66

Q5T4S7
PTAKEYFRDLYHRVD

USP7

781

Q93009
DQAYPFLHTKEDTYE

TFR2

591

Q9UP52
NVADHYGVYKPLFEA

ATP6V0D2

266

Q8N8Y2
EYRNRNFYELSPHIF

MYO1B

71

O43795
LTDQHLYKLDPDRQY

MYO1G

891

B0I1T2
SAFHLKQPEEYHYLN

MYO9A

351

B2RTY4
DVFYNTKPYKHRDDR

PCSK1

726

P29120