Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmiRNA binding

AGO2 AGO1 AGO4 AGO3

7.69e-0748304GO:0035198
GeneOntologyMolecularFunctionregulatory RNA binding

AGO2 AGO1 AGO4 AGO3

2.17e-0662304GO:0061980
GeneOntologyMolecularFunctionpeptide lactyltransferase (CoA-dependent) activity

CREBBP EP300

2.18e-062302GO:0120300
GeneOntologyMolecularFunctionendoribonuclease activity, cleaving miRNA-paired mRNA

AGO2 AGO3

2.18e-062302GO:0090624
GeneOntologyMolecularFunctionhistone H3K27 acetyltransferase activity

CREBBP EP300

2.18e-062302GO:0044017
GeneOntologyMolecularFunctiondouble-stranded RNA binding

AGO2 AGO1 AGO4 AGO3

5.46e-0678304GO:0003725
GeneOntologyMolecularFunctionRNA endonuclease activity

AGO2 AGO1 AGO4 AGO3

5.75e-0679304GO:0004521
GeneOntologyMolecularFunctionhistone H3K18 acetyltransferase activity

CREBBP EP300

6.54e-063302GO:0043993
GeneOntologyMolecularFunctionsingle-stranded RNA binding

AGO2 AGO1 AGO4 AGO3

2.22e-05111304GO:0003727
GeneOntologyMolecularFunctionRNA nuclease activity

AGO2 AGO1 AGO4 AGO3

4.92e-05136304GO:0004540
GeneOntologyMolecularFunctionendonuclease activity

AGO2 AGO1 AGO4 AGO3

4.92e-05136304GO:0004519
GeneOntologyMolecularFunctionhistone acetyltransferase activity

SRCAP CREBBP EP300

6.07e-0551303GO:0004402
GeneOntologyMolecularFunctionpeptide-lysine-N-acetyltransferase activity

SRCAP CREBBP EP300

7.62e-0555303GO:0061733
GeneOntologyMolecularFunctionpeptide N-acetyltransferase activity

SRCAP CREBBP EP300

9.88e-0560303GO:0034212
GeneOntologyMolecularFunctionbasal RNA polymerase II transcription machinery binding

AGO2 AGO1 CREBBP

1.31e-0466303GO:0001099
GeneOntologyMolecularFunctionbasal transcription machinery binding

AGO2 AGO1 CREBBP

1.31e-0466303GO:0001098
GeneOntologyMolecularFunctionN-acetyltransferase activity

SRCAP CREBBP EP300

2.16e-0478303GO:0008080
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

CREBBP EP300

2.26e-0415302GO:0010484
GeneOntologyMolecularFunctionhistone modifying activity

SRCAP CREBBP EP300 PRDM2

3.65e-04229304GO:0140993
GeneOntologyMolecularFunctionnuclease activity

AGO2 AGO1 AGO4 AGO3

3.78e-04231304GO:0004518
GeneOntologyMolecularFunctionperoxisome proliferator activated receptor binding

CREBBP EP300

4.50e-0421302GO:0042975
GeneOntologyMolecularFunctionN-acyltransferase activity

SRCAP CREBBP EP300

4.75e-04102303GO:0016410
GeneOntologyMolecularFunctionacetyltransferase activity

SRCAP CREBBP EP300

5.03e-04104303GO:0016407
GeneOntologyMolecularFunctiontranscription coregulator binding

CREBBP USP11 EP300

1.19e-03140303GO:0001221
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

AGO2 AGO3

1.41e-0337302GO:0016891
GeneOntologyMolecularFunctionbHLH transcription factor binding

CREBBP EP300

1.41e-0337302GO:0043425
GeneOntologyMolecularFunctionRNA polymerase II complex binding

AGO2 AGO1

1.56e-0339302GO:0000993
GeneOntologyMolecularFunctionRNA polymerase core enzyme binding

AGO2 AGO1

2.08e-0345302GO:0043175
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

AGO2 AGO3

2.17e-0346302GO:0016893
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

AGO2 AGO1 AGO4 SRCAP AGO3

2.52e-03645305GO:0140640
GeneOntologyMolecularFunctiontranscription coactivator binding

CREBBP EP300

2.97e-0354302GO:0001223
GeneOntologyMolecularFunctioncore promoter sequence-specific DNA binding

AGO2 AGO1

3.08e-0355302GO:0001046
GeneOntologyMolecularFunctionHsp90 protein binding

AGO2 PPEF2

3.08e-0355302GO:0051879
GeneOntologyMolecularFunctioncatalytic activity, acting on RNA

AGO2 AGO1 AGO4 AGO3

3.34e-03417304GO:0140098
GeneOntologyMolecularFunctionHsp70 protein binding

AGO2 PPEF2

4.03e-0363302GO:0030544
GeneOntologyMolecularFunctionRNA polymerase binding

AGO2 AGO1

4.28e-0365302GO:0070063
GeneOntologyMolecularFunctionacyltransferase activity, transferring groups other than amino-acyl groups

SRCAP CREBBP EP300

5.35e-03238303GO:0016747
GeneOntologyMolecularFunctionp53 binding

CREBBP EP300

5.95e-0377302GO:0002039
GeneOntologyMolecularFunctionhydrolase activity, acting on ester bonds

AGO2 AGO1 AGO4 PPEF2 AGO3

6.55e-03807305GO:0016788
GeneOntologyMolecularFunctiondamaged DNA binding

CREBBP EP300

7.05e-0384302GO:0003684
GeneOntologyMolecularFunctionSMAD binding

CREBBP EP300

7.37e-0386302GO:0046332
GeneOntologyMolecularFunctionprotein kinase binding

MLKL SRCIN1 PPEF2 LYST EP300

9.06e-03873305GO:0019901
GeneOntologyMolecularFunctiontranscription coactivator activity

SRCAP CREBBP EP300

1.04e-02303303GO:0003713
GeneOntologyMolecularFunctionkinase binding

MLKL SRCIN1 PPEF2 LYST EP300

1.38e-02969305GO:0019900
GeneOntologyBiologicalProcesssiRNA-mediated gene silencing by mRNA destabilization

AGO2 AGO1 AGO4 AGO3

3.64e-124304GO:0090625
GeneOntologyBiologicalProcesssiRNA-mediated post-transcriptional gene silencing

AGO2 AGO1 AGO4 AGO3

3.64e-124304GO:0140766
GeneOntologyBiologicalProcessRNA secondary structure unwinding

AGO2 AGO1 AGO4 AGO3

4.56e-109304GO:0010501
GeneOntologyBiologicalProcessRISC complex assembly

AGO2 AGO1 AGO4 AGO3

7.59e-1010304GO:0070922
GeneOntologyBiologicalProcesspre-miRNA processing

AGO2 AGO1 AGO4 AGO3

8.54e-0917304GO:0031054
GeneOntologyBiologicalProcessmiRNA processing

AGO2 AGO1 AGO4 AGO3

6.77e-0748304GO:0035196
GeneOntologyBiologicalProcessregulatory ncRNA processing

AGO2 AGO1 AGO4 AGO3

3.90e-0674304GO:0070918
GeneOntologyBiologicalProcessN-terminal peptidyl-lysine acetylation

CREBBP EP300

1.22e-054302GO:0018076
GeneOntologyBiologicalProcessmiRNA-mediated gene silencing by inhibition of translation

AGO2 AGO1 AGO4 AGO3

1.63e-05106304GO:0035278
GeneOntologyBiologicalProcessmiRNA-mediated gene silencing by mRNA destabilization

AGO2 AGO1 AGO4 AGO3

1.82e-05109304GO:0035279
GeneOntologyBiologicalProcessmiRNA metabolic process

AGO2 AGO1 AGO4 EP300

2.57e-05119304GO:0010586
GeneOntologyBiologicalProcesspositive regulation of non-canonical NF-kappaB signal transduction

AGO1 AGO3 CREBBP

1.55e-0472303GO:1901224
GeneOntologyBiologicalProcessmRNA destabilization

AGO2 AGO1 AGO4 AGO3

2.16e-04206304GO:0061157
GeneOntologyBiologicalProcessRNA destabilization

AGO2 AGO1 AGO4 AGO3

2.37e-04211304GO:0050779
GeneOntologyBiologicalProcesspositive regulation of mRNA catabolic process

AGO2 AGO1 AGO4 AGO3

2.37e-04211304GO:0061014
GeneOntologyBiologicalProcessN-terminal protein amino acid acetylation

CREBBP EP300

2.42e-0416302GO:0006474
GeneOntologyBiologicalProcessregulation of cellular response to heat

CREBBP EP300

2.42e-0416302GO:1900034
GeneOntologyBiologicalProcessnegative regulation of translation

AGO2 AGO1 AGO4 AGO3

3.29e-04230304GO:0017148
GeneOntologyBiologicalProcesscellular response to hepatocyte growth factor stimulus

ADAMTS12 CREBBP

3.44e-0419302GO:0035729
GeneOntologyBiologicalProcessregulation of mRNA metabolic process

PTBP3 AGO2 AGO1 AGO4 AGO3

4.09e-04443305GO:1903311
GeneOntologyBiologicalProcessprotein-RNA complex assembly

AGO2 AGO1 AGO4 AGO3

4.11e-04244304GO:0022618
GeneOntologyBiologicalProcessresponse to hepatocyte growth factor

ADAMTS12 CREBBP

4.22e-0421302GO:0035728
GeneOntologyBiologicalProcessnucleobase-containing compound catabolic process

AGO2 HK1 AGO1 AGO4 AGO3 EP300

4.29e-04696306GO:0034655
GeneOntologyBiologicalProcessprotein-RNA complex organization

AGO2 AGO1 AGO4 AGO3

4.78e-04254304GO:0071826
GeneOntologyBiologicalProcessstimulatory C-type lectin receptor signaling pathway

CREBBP EP300

5.08e-0423302GO:0002223
GeneOntologyBiologicalProcesscellular response to lectin

CREBBP EP300

5.08e-0423302GO:1990858
GeneOntologyBiologicalProcessresponse to lectin

CREBBP EP300

5.08e-0423302GO:1990840
GeneOntologyBiologicalProcesspositive regulation of mRNA metabolic process

AGO2 AGO1 AGO4 AGO3

5.15e-04259304GO:1903313
GeneOntologyBiologicalProcessregulation of translation

AGO2 AGO1 AGO4 AGO3 EP300

6.71e-04494305GO:0006417
GeneOntologyBiologicalProcessregulation of non-canonical NF-kappaB signal transduction

AGO1 AGO3 CREBBP

6.95e-04120303GO:1901222
GeneOntologyBiologicalProcesspeptidyl-lysine acetylation

CREBBP EP300

7.55e-0428302GO:0018394
GeneOntologyBiologicalProcessregulation of mRNA stability

AGO2 AGO1 AGO4 AGO3

8.07e-04292304GO:0043488
GeneOntologyBiologicalProcessN-terminal protein amino acid modification

CREBBP EP300

8.10e-0429302GO:0031365
GeneOntologyBiologicalProcessregulation of synapse maturation

ADGRL1 AGO2

9.26e-0431302GO:0090128
GeneOntologyBiologicalProcessregulation of RNA stability

AGO2 AGO1 AGO4 AGO3

9.84e-04308304GO:0043487
GeneOntologyBiologicalProcessregulation of mRNA catabolic process

AGO2 AGO1 AGO4 AGO3

9.96e-04309304GO:0061013
GeneOntologyBiologicalProcesstranslation

AGO2 AGO1 AGO4 AGO3 RPL3L EP300

1.04e-03824306GO:0006412
GeneOntologyBiologicalProcesspositive regulation of cellular response to transforming growth factor beta stimulus

CREBBP EP300

1.18e-0335302GO:1903846
GeneOntologyBiologicalProcesspositive regulation of transforming growth factor beta receptor signaling pathway

CREBBP EP300

1.18e-0335302GO:0030511
GeneOntologyBiologicalProcessnon-canonical NF-kappaB signal transduction

AGO1 AGO3 CREBBP

1.33e-03150303GO:0038061
GeneOntologyBiologicalProcessface morphogenesis

CREBBP EP300

1.62e-0341302GO:0060325
GeneOntologyBiologicalProcessmRNA metabolic process

ESRP2 PTBP3 AGO2 AGO1 AGO4 AGO3

1.80e-03917306GO:0016071
GeneOntologyCellularComponentRISC-loading complex

AGO2 AGO1 AGO4 AGO3

7.19e-1010304GO:0070578
GeneOntologyCellularComponentendoribonuclease complex

AGO2 AGO1 AGO4 AGO3

2.20e-0737304GO:1902555
GeneOntologyCellularComponentendonuclease complex

AGO2 AGO1 AGO4 AGO3

4.09e-0743304GO:1905348
GeneOntologyCellularComponentP-body

AGO2 AGO1 AGO4 AGO3

1.33e-05102304GO:0000932
GeneOntologyCellularComponentintracellular protein-containing complex

AGO2 AGO1 AGO4 AGO3 CREBBP EP300 TRAPPC9

3.66e-04972307GO:0140535
GeneOntologyCellularComponentcytoplasmic ribonucleoprotein granule

AGO2 AGO1 AGO4 AGO3

5.65e-04269304GO:0036464
GeneOntologyCellularComponentribonucleoprotein granule

AGO2 AGO1 AGO4 AGO3

7.20e-04287304GO:0035770
GeneOntologyCellularComponentRISC complex

AGO2 AGO1 AGO4 AGO3

2.96e-03422304GO:0016442
GeneOntologyCellularComponentRNAi effector complex

AGO2 AGO1 AGO4 AGO3

2.99e-03423304GO:0031332
HumanPhenoThin upper lip vermilion

AGO2 HK1 AGO1 SRCAP CREBBP EP300 TRAPPC9 SCN1A

7.48e-07339148HP:0000219
HumanPhenoThin lips

AGO2 HK1 AGO1 SRCAP CREBBP EP300 TRAPPC9 SCN1A

7.48e-07339148HP:0000213
HumanPhenoJuvenile aseptic necrosis

PHF6 SRCAP CREBBP EP300

4.15e-0643144HP:0100323
HumanPhenoThin vermilion border

AGO2 HK1 AGO1 SRCAP CREBBP EP300 TRAPPC9 SCN1A

4.86e-06433148HP:0000233
HumanPhenoDelayed ability to walk

ADGRL1 HK1 AGO1 SRCAP CREBBP EP300 TRAPPC9

6.01e-06304147HP:0031936
HumanPhenoPlantar crease between first and second toes

CREBBP EP300

7.02e-062142HP:0008107
HumanPhenoAortic isthmus hypoplasia

CREBBP EP300

7.02e-062142HP:0034227
HumanPhenoHigh axial triradius

CREBBP EP300

7.02e-062142HP:0001042
HumanPhenoAbnormality of upper lip vermillion

AGO2 HK1 AGO1 SRCAP CREBBP EP300 TRAPPC9 SCN1A

8.19e-06464148HP:0011339
HumanPhenoLaryngeal cartilage malformation

CREBBP EP300

2.10e-053142HP:0008752
HumanPhenoPhobia

CREBBP EP300

2.10e-053142HP:5200232
HumanPhenoAgoraphobia

CREBBP EP300

2.10e-053142HP:0000756
HumanPhenoHumoral immunodeficiency

CREBBP EP300

2.10e-053142HP:0005363
HumanPhenoProminent nasal septum

CREBBP EP300

2.10e-053142HP:0005322
HumanPhenoRadial deviation of thumb terminal phalanx

CREBBP EP300

2.10e-053142HP:0005895
HumanPhenoRestricted or repetitive behaviors or interests

ADGRL1 AGO1 SRCAP CREBBP EP300 TRAPPC9 SCN1A

2.14e-05368147HP:0031432
HumanPhenoPerseverative thought

ADGRL1 AGO1 SRCAP CREBBP EP300 TRAPPC9 SCN1A

2.50e-05377147HP:0030223
HumanPhenoDisordered formal thought process

ADGRL1 AGO1 SRCAP CREBBP EP300 TRAPPC9 SCN1A

2.92e-05386147HP:0025769
HumanPhenoHyperactivity

ADGRL1 AGO2 AGO1 SRCAP CREBBP EP300 TRAPPC9 SCN1A

3.25e-05558148HP:0000752
HumanPhenoAbnormal thought pattern

ADGRL1 AGO1 SRCAP CREBBP EP300 TRAPPC9 SCN1A

3.94e-05404147HP:5200269
HumanPhenoPhonophobia

CREBBP EP300 SCN1A

4.14e-0526143HP:0002183
HumanPhenoTrichiasis

CREBBP EP300

4.20e-054142HP:0001128
HumanPhenoVisceral hemangioma

CREBBP EP300

4.20e-054142HP:0410266
HumanPhenoTalon cusp

CREBBP EP300

4.20e-054142HP:0011087
HumanPhenoWidened distal phalanges

CREBBP EP300

4.20e-054142HP:0006200
HumanPhenoVascular ring

CREBBP EP300

4.20e-054142HP:0010775
HumanPhenoHepatic hemangioma

CREBBP EP300

4.20e-054142HP:0031207
HumanPhenoMotor stereotypy

ADGRL1 AGO1 CREBBP EP300 TRAPPC9 SCN1A

5.40e-05280146HP:0000733
HumanPhenoTruncal obesity

PHF6 CREBBP EP300 TRAPPC9

5.52e-0582144HP:0001956
HumanPhenoAvascular necrosis of the capital femoral epiphysis

SRCAP CREBBP EP300

6.42e-0530143HP:0005743
HumanPhenoAbnormal epididymis morphology

SRCAP CREBBP EP300

6.42e-0530143HP:0009714
HumanPhenoPapillary cystadenoma of the epididymis

CREBBP EP300

6.98e-055142HP:0009715
HumanPhenoSupernumerary cusp

CREBBP EP300

6.98e-055142HP:0033777
HumanPhenoEpididymal neoplasm

CREBBP EP300

6.98e-055142HP:0030421
HumanPhenoAvascular necrosis

PHF6 SRCAP CREBBP EP300

8.69e-0592144HP:0010885
HumanPhenoLarge foramen magnum

CREBBP EP300

1.05e-046142HP:0002700
HumanPhenoDisturbance of facial expression

CREBBP EP300 SCN1A

1.12e-0436143HP:0005324
HumanPhenoAuditory sensitivity

CREBBP EP300 SCN1A

1.22e-0437143HP:0025112
HumanPhenoAuditory hypersensitivity

CREBBP EP300 SCN1A

1.22e-0437143HP:5200060
HumanPhenoDelayed gross motor development

ADGRL1 HK1 AGO1 SRCAP CREBBP EP300 TRAPPC9

1.22e-04481147HP:0002194
HumanPhenoDeviated nasal septum

CREBBP EP300

1.46e-047142HP:0004411
HumanPhenoWide nasal bridge

AGO2 AGO1 SRCAP CREBBP EP300 TRAPPC9 SCN1A

1.73e-04508147HP:0000431
HumanPhenoShort attention span

ADGRL1 AGO2 AGO1 SRCAP CREBBP EP300 SCN1A

1.94e-04517147HP:0000736
HumanPhenoReduced attention regulation

ADGRL1 AGO2 AGO1 SRCAP CREBBP EP300 SCN1A

2.16e-04526147HP:5200044
HumanPhenoPilomatrixoma

CREBBP EP300

2.50e-049142HP:0030434
HumanPhenoCervical cord compression

CREBBP EP300

2.50e-049142HP:0002341
HumanPhenoFrontal hirsutism

CREBBP EP300

3.12e-0410142HP:0011335
HumanPhenoAbnormal proximal phalanx morphology of the hand

SRCAP CREBBP EP300

3.37e-0452143HP:0009834
HumanPhenoNarrow nasal bridge

SRCAP CREBBP EP300

3.57e-0453143HP:0000446
HumanPhenoMotor delay

ADGRL1 AGO2 HK1 AGO1 SRCAP CREBBP EP300 TRAPPC9 SCN1A

3.72e-041018149HP:0001270
HumanPhenoDislocated radial head

SRCAP CREBBP EP300

3.77e-0454143HP:0003083
HumanPhenoAbnormal subclavian artery morphology

CREBBP EP300

3.80e-0411142HP:0031251
HumanPhenoPatent foramen ovale

AGO2 RPL3L CREBBP EP300

3.84e-04135144HP:0001655
HumanPhenoLow hanging columella

SRCAP CREBBP EP300

4.20e-0456143HP:0009765
HumanPhenoAbnormality of the radial head

SRCAP CREBBP EP300

4.43e-0457143HP:0003995
HumanPhenoDisinhibition

ADGRL1 AGO2 AGO1 SRCAP CREBBP EP300 TRAPPC9 SCN1A

4.71e-04807148HP:0000734
HumanPhenoInappropriate behavior

ADGRL1 AGO2 AGO1 SRCAP CREBBP EP300 TRAPPC9 SCN1A

4.71e-04807148HP:0000719
HumanPhenoAbnormal response to social norms

ADGRL1 AGO2 AGO1 SRCAP CREBBP EP300 TRAPPC9 SCN1A

4.71e-04807148HP:5200123
HumanPhenoSocial disinhibition

ADGRL1 AGO2 AGO1 SRCAP CREBBP EP300 TRAPPC9 SCN1A

4.71e-04807148HP:5200029
HumanPhenoAbnormal scrotum morphology

PHF6 SRCAP CREBBP EP300

4.79e-04143144HP:0000045
HumanPhenoDeeply set eye

PHF6 AGO2 SRCAP CREBBP EP300

5.07e-04266145HP:0000490
HumanPhenoFacial grimacing

CREBBP EP300

5.38e-0413142HP:0000273
HumanPhenoKeloids

CREBBP EP300

5.38e-0413142HP:0010562
HumanPhenoImpulsivity

SRCAP CREBBP EP300 SCN1A

5.60e-04149144HP:0100710
HumanPhenoAbnormality of the humeroradial joint

SRCAP CREBBP EP300

5.68e-0462143HP:0100744
HumanPhenoEpicanthus

AGO2 HK1 AGO1 SRCAP CREBBP EP300 TRAPPC9

5.71e-04614147HP:0000286
HumanPhenoDuplication of phalanx of hallux

CREBBP EP300

6.26e-0414142HP:0010066
HumanPhenoHypoplastic aortic arch

CREBBP EP300

6.26e-0414142HP:0012304
HumanPhenoParietal foramina

CREBBP EP300

6.26e-0414142HP:0002697
HumanPhenoCompulsive behaviors

SRCAP CREBBP EP300 SCN1A

6.99e-04158144HP:0000722
HumanPhenoDuplication of phalanx of toe

CREBBP EP300

7.22e-0415142HP:0010181
HumanPhenoSocial and occupational deterioration

CREBBP EP300

7.22e-0415142HP:0007086
HumanPhenoAbnormally increased volition

ADGRL1 AGO2 AGO1 SRCAP CREBBP EP300 TRAPPC9 SCN1A

7.93e-04869148HP:5200263
HumanPhenoDelayed speech and language development

ADGRL1 AGO2 HK1 AGO1 SRCAP CREBBP EP300 TRAPPC9 SCN1A

8.06e-041123149HP:0000750
HumanPhenoSquare face

CREBBP EP300

8.23e-0416142HP:0000321
HumanPhenoPremature thelarche

CREBBP EP300

9.32e-0417142HP:0010314
HumanPhenoAbnormal distal phalanx morphology of finger

PHF6 SRCAP CREBBP EP300

1.01e-03174144HP:0009832
HumanPhenoFacial hirsutism

CREBBP EP300

1.05e-0318142HP:0009937
HumanPhenoSkin appendage neoplasm

CREBBP EP300

1.05e-0318142HP:0012842
HumanPhenoAutistic behavior

ADGRL1 AGO2 AGO1 SRCAP CREBBP EP300 SCN1A

1.05e-03678147HP:0000729
HumanPhenoAbnormal social development

ADGRL1 AGO2 AGO1 SRCAP CREBBP EP300 TRAPPC9 SCN1A

1.08e-03908148HP:0025732
HumanPhenoSensory hypersensitivity

HK1 LYST CREBBP EP300 SCN1A

1.17e-03319145HP:5200058
HumanPhenoLanguage impairment

ADGRL1 AGO2 HK1 AGO1 SRCAP CREBBP EP300 TRAPPC9 SCN1A

1.17e-031178149HP:0002463
HumanPhenoPrecocious puberty

SRCAP CREBBP EP300 SCN1A

1.29e-03186144HP:0000826
HumanPhenoAbsent earlobe

CREBBP EP300

1.30e-0320142HP:0000387
HumanPhenoAbnormality of the epiphysis of the femoral head

SRCAP CREBBP EP300

1.33e-0383143HP:0010574
HumanPhenoPersistent left superior vena cava

SRCAP CREBBP EP300

1.33e-0383143HP:0005301
HumanPhenoEarly onset of sexual maturation

SRCAP CREBBP EP300 SCN1A

1.37e-03189144HP:0100000
HumanPhenoElbow dislocation

SRCAP CREBBP EP300

1.38e-0384143HP:0003042
HumanPhenoAbnormal superior vena cava morphology

SRCAP CREBBP EP300

1.43e-0385143HP:0025575
HumanPhenoLocalized hirsutism

CREBBP EP300

1.43e-0321142HP:0009889
HumanPhenoDeep plantar creases

CREBBP EP300

1.43e-0321142HP:0001869
HumanPhenoCorneal scarring

CREBBP EP300

1.43e-0321142HP:0000559
HumanPhenoAbnormal femoral epiphysis morphology

SRCAP CREBBP EP300

1.48e-0386143HP:0006499
HumanPhenoSensory behavioral abnormality

HK1 LYST CREBBP EP300 SCN1A

1.50e-03337145HP:5200046
HumanPhenoAggressive behavior

AGO2 AGO1 SRCAP CREBBP EP300 SCN1A

1.55e-03516146HP:0000718
HumanPhenoAbnormal aggressive, impulsive or violent behavior

AGO2 AGO1 SRCAP CREBBP EP300 SCN1A

1.55e-03516146HP:0006919
HumanPhenoAbnormal vena cava morphology

SRCAP CREBBP EP300

1.58e-0388143HP:0030971
HumanPhenoAbnormal vena cava morphology

SRCAP CREBBP EP300

1.63e-0389143HP:0005345
HumanPhenoBroad thumb

SRCAP CREBBP EP300

1.69e-0390143HP:0011304
DomainArgonaute_N

AGO2 AGO1 AGO4 AGO3

4.04e-124284IPR032474
DomainArgonaute_Mid_dom

AGO2 AGO1 AGO4 AGO3

4.04e-124284IPR032473
DomainArgoL2

AGO2 AGO1 AGO4 AGO3

4.04e-124284IPR032472
DomainArgoN

AGO2 AGO1 AGO4 AGO3

4.04e-124284PF16486
DomainArgoMid

AGO2 AGO1 AGO4 AGO3

4.04e-124284PF16487
DomainArgoL2

AGO2 AGO1 AGO4 AGO3

4.04e-124284PF16488
DomainDUF1785

AGO2 AGO1 AGO4 AGO3

2.02e-115284SM01163
DomainArgoL1

AGO2 AGO1 AGO4 AGO3

6.05e-116284PF08699
DomainArgoL1

AGO2 AGO1 AGO4 AGO3

6.05e-116284IPR014811
DomainPIWI

AGO2 AGO1 AGO4 AGO3

2.82e-108284PS50822
DomainPiwi

AGO2 AGO1 AGO4 AGO3

2.82e-108284IPR003165
DomainPiwi

AGO2 AGO1 AGO4 AGO3

2.82e-108284PF02171
DomainPiwi

AGO2 AGO1 AGO4 AGO3

2.82e-108284SM00950
DomainPAZ

AGO2 AGO1 AGO4 AGO3

5.06e-109284PS50821
DomainPAZ_dom

AGO2 AGO1 AGO4 AGO3

5.06e-109284IPR003100
DomainPAZ

AGO2 AGO1 AGO4 AGO3

5.06e-109284PF02170
DomainPAZ

AGO2 AGO1 AGO4 AGO3

5.06e-109284SM00949
Domain-

ESRP2 AGO2 AGO1 AGO4 AGO3

7.63e-09472853.30.420.10
DomainRNaseH-like_dom

ESRP2 AGO2 AGO1 AGO4 AGO3

5.46e-0869285IPR012337
Domain-

CREBBP EP300

2.17e-0622821.10.246.20
Domainzf-TAZ

CREBBP EP300

2.17e-062282PF02135
DomainZF_TAZ

CREBBP EP300

2.17e-062282PS50134
DomainNuc_rcpt_coact_CREBbp

CREBBP EP300

2.17e-062282IPR014744
DomainHAT_KAT11

CREBBP EP300

2.17e-062282PF08214
DomainKIX

CREBBP EP300

2.17e-062282PS50952
DomainZnF_TAZ

CREBBP EP300

2.17e-062282SM00551
DomainCBP_P300_HAT

CREBBP EP300

2.17e-062282IPR031162
DomainHistone_AcTrfase_Rtt109/CBP

CREBBP EP300

2.17e-062282IPR013178
DomainDUF902

CREBBP EP300

2.17e-062282PF06001
Domain-

CREBBP EP300

2.17e-0622821.20.1020.10
DomainRING_CBP-p300

CREBBP EP300

2.17e-062282IPR010303
DomainKAT11

CREBBP EP300

2.17e-062282SM01250
Domain-

CREBBP EP300

2.17e-0622821.10.1630.10
DomainZnf_TAZ

CREBBP EP300

2.17e-062282IPR000197
DomainKIX_dom

CREBBP EP300

2.17e-062282IPR003101
DomainCreb_binding

CREBBP EP300

2.17e-062282PF09030
DomainKIX

CREBBP EP300

2.17e-062282PF02172
DomainCBP_P300_HAT

CREBBP EP300

2.17e-062282PS51727
DomainNuc_rcpt_coact

CREBBP EP300

3.24e-056282IPR009110
DomainZF_ZZ_2

CREBBP EP300

3.27e-0418282PS50135
DomainZF_ZZ_1

CREBBP EP300

3.27e-0418282PS01357
DomainZZ

CREBBP EP300

3.27e-0418282PF00569
DomainZnf_ZZ

CREBBP EP300

3.65e-0419282IPR000433
DomainZnF_ZZ

CREBBP EP300

3.65e-0419282SM00291
DomainBromodomain_CS

CREBBP EP300

6.89e-0426282IPR018359
DomainBROMODOMAIN_1

CREBBP EP300

1.40e-0337282PS00633
DomainBromodomain

CREBBP EP300

1.47e-0338282PF00439
DomainBROMODOMAIN_2

CREBBP EP300

1.71e-0341282PS50014
DomainBROMO

CREBBP EP300

1.80e-0342282SM00297
DomainBromodomain

CREBBP EP300

1.80e-0342282IPR001487
Domain-

CREBBP EP300

1.80e-03422821.20.920.10
DomainIQ

PPEF2 SCN1A

5.05e-0371282PF00612
DomainIQ

PPEF2 SCN1A

6.53e-0381282SM00015
PathwayBIOCARTA_DICER_PATHWAY

AGO2 AGO1 AGO4 AGO3

3.23e-115244M22079
PathwayREACTOME_MICRORNA_MIRNA_BIOGENESIS

AGO2 AGO1 AGO4 AGO3

9.67e-116244MM14818
PathwayREACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS

AGO2 AGO1 AGO4 AGO3

9.67e-116244MM15083
PathwayREACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS

AGO2 AGO1 AGO4 AGO3

2.25e-107244M46421
PathwayREACTOME_SMALL_INTERFERING_RNA_SIRNA_BIOGENESIS

AGO2 AGO1 AGO4 AGO3

4.50e-108244MM15082
PathwayREACTOME_SMALL_INTERFERING_RNA_SIRNA_BIOGENESIS

AGO2 AGO1 AGO4 AGO3

8.09e-109244M27340
PathwayREACTOME_REGULATION_OF_PTEN_MRNA_TRANSLATION

AGO2 AGO1 AGO4 AGO3

8.09e-109244M27810
PathwayREACTOME_REGULATION_OF_NPAS4_MRNA_TRANSLATION

AGO2 AGO1 AGO4 AGO3

8.09e-109244M46436
PathwayREACTOME_TGFBR3_EXPRESSION

AGO2 AGO1 AGO4 AGO3 EP300

8.78e-1028245M48253
PathwayREACTOME_REGULATION_OF_CDH11_MRNA_TRANSLATION_BY_MICRORNAS

AGO2 AGO1 AGO4 AGO3

1.35e-0910244M48013
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_NPAS4

AGO2 AGO1 AGO4 AGO3 CREBBP

2.47e-0934245M46422
PathwayREACTOME_NR1H3_NR1H2_REGULATE_GENE_EXPRESSION_LINKED_TO_CHOLESTEROL_TRANSPORT_AND_EFFLUX

AGO2 AGO1 AGO4 AGO3 EP300

3.86e-0937245M29790
PathwayREACTOME_REGULATION_OF_NPAS4_GENE_EXPRESSION

AGO2 AGO1 AGO4 AGO3

4.57e-0913244M46434
PathwayREACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING

AGO2 AGO1 AGO4 AGO3 EP300

1.34e-0847245M29777
PathwayREACTOME_REGULATION_OF_RUNX1_EXPRESSION_AND_ACTIVITY

AGO2 AGO1 AGO4 AGO3

1.52e-0817244M27788
PathwayREACTOME_SIGNALING_BY_TGFBR3

AGO2 AGO1 AGO4 AGO3 EP300

1.66e-0849245M48250
PathwayREACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_APOPTOSIS

AGO2 AGO1 AGO4 AGO3

2.46e-0819244M48238
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

AGO2 AGO1 AGO4 AGO3 CREBBP EP300

3.79e-08119246M607
PathwayREACTOME_MICRORNA_MIRNA_BIOGENESIS

AGO2 AGO1 AGO4 AGO3

7.98e-0825244M712
PathwayREACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION

AGO2 AGO1 AGO4 AGO3 CREBBP EP300

1.45e-07149246M27888
PathwayREACTOME_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION

AGO2 AGO1 AGO4 AGO3

2.25e-0732244M48012
PathwayREACTOME_REGULATION_OF_MECP2_EXPRESSION_AND_ACTIVITY

AGO2 AGO1 AGO4 AGO3

2.25e-0732244M27900
PathwayREACTOME_NUCLEAR_EVENTS_STIMULATED_BY_ALK_SIGNALING_IN_CANCER

AGO2 AGO1 AGO4 AGO3

3.27e-0735244M42525
PathwayREACTOME_GENE_SILENCING_BY_RNA

AGO2 AGO1 AGO4 AGO3

1.30e-0649244MM14837
PathwayREACTOME_ESR_MEDIATED_SIGNALING

AGO2 AGO1 AGO4 AGO3 CREBBP EP300

1.44e-06220246M27794
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1

AGO2 AGO1 AGO4 AGO3 CREBBP EP300

2.21e-06237246M27786
PathwayREACTOME_ADHERENS_JUNCTIONS_INTERACTIONS

AGO2 AGO1 AGO4 AGO3

2.58e-0658244M11980
PathwayREACTOME_SIGNALING_BY_NOTCH

AGO2 AGO1 AGO4 AGO3 CREBBP EP300

2.75e-06246246M10189
PathwayREACTOME_MITF_M_REGULATED_MELANOCYTE_DEVELOPMENT

AGO2 AGO1 AGO4 AGO3 CREBBP

2.95e-06137245M48232
PathwayREACTOME_CA2_PATHWAY

AGO2 AGO1 AGO4 AGO3

3.37e-0662244M27321
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_MECP2

AGO2 AGO1 AGO4 AGO3

3.60e-0663244M27862
PathwayREACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS

AGO2 AGO1 AGO4 AGO3 EP300

6.51e-06161245M27871
PathwayREACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS

AGO2 AGO1 AGO4 AGO3 CREBBP EP300

7.97e-06296246M27869
PathwayREACTOME_TP53_REGULATES_METABOLIC_GENES

AGO2 AGO1 AGO4 AGO3

1.14e-0584244M27495
PathwayREACTOME_SIGNALING_BY_WNT

AGO2 AGO1 AGO4 AGO3 CREBBP EP300

1.48e-05330246M7847
PathwayREACTOME_CELL_CELL_JUNCTION_ORGANIZATION

AGO2 AGO1 AGO4 AGO3

1.50e-0590244M820
PathwayREACTOME_MAPK6_MAPK4_SIGNALING

AGO2 AGO1 AGO4 AGO3

1.70e-0593244M27572
PathwayREACTOME_SIGNALING_BY_ALK_IN_CANCER

AGO2 AGO1 AGO4 AGO3

1.70e-0593244M42521
PathwayREACTOME_MITF_M_DEPENDENT_GENE_EXPRESSION

AGO2 AGO1 AGO4 AGO3

1.85e-0595244M48268
PathwayREACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION

AGO1 AGO4 AGO3 EP300

1.93e-0596244M27792
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53

AGO2 AGO1 AGO4 AGO3 CREBBP EP300

2.43e-05360246M27267
PathwayREACTOME_ONCOGENE_INDUCED_SENESCENCE

AGO1 AGO4 AGO3

2.74e-0535243M27190
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

2.77e-055242MM1575
PathwayREACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES

CREBBP EP300

2.77e-055242M48020
PathwayREACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION

CREBBP EP300

2.77e-055242M27228
PathwayREACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES

CREBBP EP300

2.77e-055242M48023
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

4.15e-056242M22062
PathwayREACTOME_CELL_JUNCTION_ORGANIZATION

AGO2 AGO1 AGO4 AGO3

4.21e-05117244M19248
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_VENTX

AGO1 AGO4 AGO3

4.43e-0541243M29748
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

5.80e-057242MM1573
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

7.73e-058242M22058
PathwayREACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES

CREBBP EP300

7.73e-058242M48022
PathwayREACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION

CREBBP EP300

7.73e-058242M48024
PathwayREACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES

CREBBP EP300

7.73e-058242M46443
PathwayREACTOME_PTEN_REGULATION

AGO2 AGO1 AGO4 AGO3

8.25e-05139244M27646
PathwayREACTOME_GENE_SILENCING_BY_RNA

AGO2 AGO1 AGO4 AGO3

8.25e-05139244M715
PathwayKEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY

CREBBP EP300

9.93e-059242M47451
PathwayREACTOME_BETA_CATENIN_INDEPENDENT_WNT_SIGNALING

AGO2 AGO1 AGO4 AGO3

9.99e-05146244M27288
PathwayREACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS

AGO2 AGO1 AGO4 AGO3 CREBBP EP300

1.00e-04464246M27547
PathwayREACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION

CREBBP EP300

1.24e-0410242M27945
PathwayREACTOME_CELL_CELL_COMMUNICATION

AGO2 AGO1 AGO4 AGO3

1.26e-04155244M522
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

1.51e-0411242MM1521
PathwayREACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES

CREBBP EP300

1.51e-0411242M48021
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_BY_HYPOXIA_INDUCIBLE_FACTOR

CREBBP EP300

1.51e-0411242M26924
PathwayWP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA

SRCAP CREBBP EP300

1.77e-0465243M39682
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

1.81e-0412242M7968
PathwayREACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS

CREBBP EP300

1.81e-0412242M27765
PathwayPID_HIF1_TFPATHWAY

HK1 CREBBP EP300

1.85e-0466243M255
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

CREBBP EP300

2.50e-0414242M27808
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

2.88e-0415242MM1339
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

2.88e-0415242M10183
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

2.88e-0415242MM1439
PathwayREACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY

CREBBP EP300

2.88e-0415242M953
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

3.29e-0416242M1296
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

3.29e-0416242MM1420
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

3.29e-0416242M8516
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS

CREBBP EP300

3.29e-0416242M27121
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_DEATH_GENES

CREBBP EP300

3.29e-0416242M27940
PathwayBIOCARTA_TGFB_PATHWAY

CREBBP EP300

3.72e-0417242MM1509
PathwayREACTOME_ZYGOTIC_GENOME_ACTIVATION_ZGA

CREBBP EP300

3.72e-0417242M48025
PathwayWP_CLEAR_CELL_RENAL_CELL_CARCINOMA_PATHWAYS

HK1 CREBBP EP300

4.04e-0486243M39375
PathwayREACTOME_RORA_ACTIVATES_GENE_EXPRESSION

CREBBP EP300

4.18e-0418242M26942
PathwayBIOCARTA_TGFB_PATHWAY

CREBBP EP300

4.67e-0419242M18933
PathwayREACTOME_NFE2L2_REGULATING_ANTI_OXIDANT_DETOXIFICATION_ENZYMES

CREBBP EP300

4.67e-0419242M46442
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

CREBBP EP300

5.18e-0420242M27881
PathwayWP_HEMATOPOIETIC_STEM_CELL_GENE_REGULATION_BY_GABP_ALPHABETA_COMPLEX

CREBBP EP300

5.72e-0421242M39593
PathwayREACTOME_CD209_DC_SIGN_SIGNALING

CREBBP EP300

5.72e-0421242M27485
PathwayBIOCARTA_NTHI_PATHWAY

CREBBP EP300

6.28e-0422242MM1443
PathwayBIOCARTA_VDR_PATHWAY

CREBBP EP300

6.28e-0422242MM1370
PathwayBIOCARTA_NTHI_PATHWAY

CREBBP EP300

6.88e-0423242M2821
PathwayBIOCARTA_VDR_PATHWAY

CREBBP EP300

7.49e-0424242M13404
PathwayREACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

CREBBP EP300

8.14e-0425242M27880
PathwayBIOCARTA_CARM_ER_PATHWAY

CREBBP EP300

8.81e-0426242M2499
PathwayPID_HDAC_CLASSIII_PATHWAY

CREBBP EP300

8.81e-0426242M32
PathwayREACTOME_ATTENUATION_PHASE

CREBBP EP300

1.02e-0328242M27254
PathwayPID_RETINOIC_ACID_PATHWAY

CREBBP EP300

1.17e-0330242M207
PathwayREACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION

CREBBP EP300

1.17e-0330242M936
PathwayREACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE

AGO1 AGO4 AGO3

1.20e-03125243M27186
PathwayREACTOME_MATERNAL_TO_ZYGOTIC_TRANSITION_MZT

AGO2 CREBBP EP300

1.29e-03128243M48019
PathwayWP_INITIATION_OF_TRANSCRIPTION_AND_TRANSLATION_ELONGATION_AT_THE_HIV1_LTR

CREBBP EP300

1.34e-0332242M39521
Pubmed

Molecular dissection of human Argonaute proteins by DNA shuffling.

AGO2 AGO1 AGO4 AGO3

4.50e-13430423748378
Pubmed

Slicing-independent RISC activation requires the argonaute PAZ domain.

AGO2 AGO1 AGO4 AGO3

4.50e-13430422795694
Pubmed

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs.

AGO2 AGO1 AGO4 AGO3

4.50e-13430415260970
Pubmed

ATP-dependent human RISC assembly pathways.

AGO2 AGO1 AGO4 AGO3

4.50e-13430419966796
Pubmed

Importance of translation and nonnucleolytic ago proteins for on-target RNA interference.

AGO2 AGO1 AGO4 AGO3

4.50e-13430418771919
Pubmed

Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and eIF2C translation initiation factors.

AGO2 AGO1 AGO4 AGO3

2.25e-12530412526743
Pubmed

Differential expression of Dicer and Argonaute genes during the differentiation of human neuroblastoma cells.

AGO2 AGO1 AGO4 AGO3

2.25e-12530419393748
Pubmed

The C-terminal half of human Ago2 binds to multiple GW-rich regions of GW182 and requires GW182 to mediate silencing.

AGO2 AGO1 AGO4 AGO3

2.25e-12530419324964
Pubmed

Differential expression of components of the microRNA machinery during mouse organogenesis.

AGO2 AGO1 AGO4 AGO3

2.25e-12530416036130
Pubmed

The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis.

AGO2 AGO1 AGO4 AGO3

2.25e-12530412414724
Pubmed

Genome-wide identification of microRNA targets reveals positive regulation of the Hippo pathway by miR-122 during liver development.

AGO2 AGO1 AGO4 AGO3

1.57e-11730434907157
Pubmed

Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.

AGO2 AGO1 AGO4 AGO3

1.57e-11730419536157
Pubmed

The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins.

AGO2 AGO1 AGO4 AGO3

1.57e-11730419383768
Pubmed

Functional dissection of the human TNRC6 (GW182-related) family of proteins.

AGO2 AGO1 AGO4 AGO3

1.57e-11730419470757
Pubmed

Mili interacts with tudor domain-containing protein 1 in regulating spermatogenesis.

AGO2 AGO1 AGO4 AGO3

3.14e-11830419345100
Pubmed

Suppression of microRNA Activity in Kidney Collecting Ducts Induces Partial Loss of Epithelial Phenotype and Renal Fibrosis.

AGO2 AGO1 AGO4 AGO3

3.14e-11830429021386
Pubmed

Identification of eight members of the Argonaute family in the human genome.

AGO2 AGO1 AGO4 AGO3

5.65e-11930412906857
Pubmed

Turning catalytically inactive human Argonaute proteins into active slicer enzymes.

AGO2 AGO1 AGO3

5.79e-10330323665583
Pubmed

Identification of a novel SNF2/SWI2 protein family member, SRCAP, which interacts with CREB-binding protein.

SRCAP CREBBP EP300

5.79e-10330310347196
Pubmed

The roles of individual mammalian argonautes in RNA interference in vivo.

AGO2 AGO1 AGO3

5.79e-10330324992693
Pubmed

Argonaute2 is the catalytic engine of mammalian RNAi.

AGO2 AGO1 AGO3

5.79e-10330315284456
Pubmed

Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins.

AGO2 AGO1 AGO4

5.79e-10330319946268
Pubmed

Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs.

AGO2 AGO1 AGO4 AGO3

8.12e-101630420102707
Pubmed

Argonaute proteins: potential biomarkers for human colon cancer.

AGO2 AGO4 AGO3

2.32e-09430320146808
Pubmed

Adenovirus DNA binding protein interacts with the SNF2-related CBP activator protein (SrCap) and inhibits SrCap-mediated transcription.

SRCAP CREBBP EP300

2.32e-09430311581372
Pubmed

A Requirement for Argonaute 4 in Mammalian Antiviral Defense.

AGO1 AGO4 AGO3

2.32e-09430332049003
Pubmed

Quantitative functions of Argonaute proteins in mammalian development.

AGO2 AGO1 AGO3

5.78e-09530322474261
Pubmed

Argonaute Utilization for miRNA Silencing Is Determined by Phosphorylation-Dependent Recruitment of LIM-Domain-Containing Proteins.

AGO2 AGO1 AGO3

2.02e-08730328683311
Pubmed

HIV-1 replication and APOBEC3 antiviral activity are not regulated by P bodies.

AGO2 AGO1 AGO3

9.51e-081130322915799
Pubmed

Human transcription factor protein interaction networks.

PHF6 AGO2 AGO1 SRCAP AGO3 CREBBP USP11 EP300 TRAPPC9 PRDM2

1.88e-071429301035140242
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ADNP2 MLKL AGO2 SRCAP AGO3 IQCM CREBBP USP11 EP300

2.72e-07111630931753913
Pubmed

Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.

AGO2 AGO1 AGO3 USP11

5.53e-077630427542412
Pubmed

TRIM24 is an insulin-responsive regulator of P-bodies.

AGO2 AGO1 AGO4 AGO3

6.80e-078030435803934
Pubmed

Loss of p300 accelerates MDS-associated leukemogenesis.

CREBBP EP300

7.19e-07230227881875
Pubmed

Alternative RISC assembly: binding and repression of microRNA-mRNA duplexes by human Ago proteins.

AGO2 AGO1

7.19e-07230223019594
Pubmed

Involvement of AGO1 and AGO2 in mammalian transcriptional silencing.

AGO2 AGO1

7.19e-07230216936728
Pubmed

Expression of the nuclear coactivators CBP and p300 in developing craniofacial tissue.

CREBBP EP300

7.19e-07230211963968
Pubmed

Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.

CREBBP EP300

7.19e-07230234845315
Pubmed

Human eukaryotic initiation factor EIF2C1 gene: cDNA sequence, genomic organization, localization to chromosomal bands 1p34-p35, and expression.

AGO2 AGO1

7.19e-07230210534406
Pubmed

p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.

CREBBP EP300

7.19e-07230234813504
Pubmed

Reduced Expression of Argonaute 1, Argonaute 2, and TRBP Changes Levels and Intracellular Distribution of RNAi Factors.

AGO2 AGO1

7.19e-07230226242502
Pubmed

p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.

CREBBP EP300

7.19e-07230219729597
Pubmed

Argonaute Family Protein Expression in Normal Tissue and Cancer Entities.

AGO2 AGO1

7.19e-07230227518285
Pubmed

Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.

CREBBP EP300

7.19e-07230215860545
Pubmed

Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300.

CREBBP EP300

7.19e-0723029528808
Pubmed

Analysis of genetic stability at the EP300 and CREBBP loci in a panel of cancer cell lines.

CREBBP EP300

7.19e-07230212696060
Pubmed

Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.

CREBBP EP300

7.19e-07230229460469
Pubmed

Enhanced susceptibility of Ago1/3 double-null mice to influenza A virus infection.

AGO1 AGO3

7.19e-07230222318144
Pubmed

Rubinstein-Taybi Syndrome

CREBBP EP300

7.19e-07230220301699
Pubmed

Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.

CREBBP EP300

7.19e-07230224551300
Pubmed

The Importance of AGO 1 and 4 in Post-Transcriptional Gene Regulatory Function of tRF5-GluCTC, an Respiratory Syncytial Virus-Induced tRNA-Derived RNA Fragment.

AGO1 AGO4

7.19e-07230233233493
Pubmed

CBP Is Required for Establishing Adaptive Gene Programs in the Adult Mouse Brain.

CREBBP EP300

7.19e-07230236109165
Pubmed

Potential biomarker of metformin action.

CREBBP EP300

7.19e-07230224639469
Pubmed

The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.

CREBBP EP300

7.19e-07230237816914
Pubmed

Retinoids and retinoic acid receptors regulate growth arrest and apoptosis in human mammary epithelial cells and modulate expression of CBP/p300.

CREBBP EP300

7.19e-07230212242694
Pubmed

Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.

CREBBP EP300

7.19e-07230233911074
Pubmed

The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.

CREBBP EP300

7.19e-0723029018065
Pubmed

Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.

CREBBP EP300

7.19e-07230224648406
Pubmed

CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.

CREBBP EP300

7.19e-07230230135524
Pubmed

Binding of p300/CBP co-activators by polyoma large T antigen.

CREBBP EP300

7.19e-07230211438528
Pubmed

Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.

CREBBP EP300

7.19e-07230210918613
Pubmed

CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms.

CREBBP EP300

7.19e-07230231182547
Pubmed

Human Argonaute2 and Argonaute3 are catalytically activated by different lengths of guide RNA.

AGO2 AGO3

7.19e-07230233122430
Pubmed

Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.

CREBBP EP300

7.19e-07230235502657
Pubmed

CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.

CREBBP EP300

7.19e-07230239287984
Pubmed

Rubinstein-Taybi syndrome in a Saudi boy with distinct features and variants in both the CREBBP and EP300 genes: a case report.

CREBBP EP300

7.19e-07230230635043
Pubmed

p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.

CREBBP EP300

7.19e-07230231898871
Pubmed

Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.

CREBBP EP300

7.19e-07230216596650
Pubmed

Phenotype and genotype in 52 patients with Rubinstein-Taybi syndrome caused by EP300 mutations.

CREBBP EP300

7.19e-07230227648933
Pubmed

Association of Polymorphic Variants in Argonaute Genes with Depression Risk in a Polish Population.

AGO2 AGO1

7.19e-07230236142498
Pubmed

Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.

CREBBP EP300

7.19e-07230230888860
Pubmed

Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.

CREBBP EP300

7.19e-07230227881443
Pubmed

The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.

CREBBP EP300

7.19e-07230229217654
Pubmed

Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.

CREBBP EP300

7.19e-07230219272189
Pubmed

Distinct AGO1 and AGO2 associated miRNA profiles in human cells and blood plasma.

AGO2 AGO1

7.19e-07230222858679
Pubmed

Developmentally regulated expression of the transcriptional cofactors/histone acetyltransferases CBP and p300 during mouse embryogenesis.

CREBBP EP300

7.19e-07230210610021
Pubmed

Emerging roles of p300/CBP in autophagy and autophagy-related human disorders.

CREBBP EP300

7.19e-07230237314181
Pubmed

Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.

CREBBP EP300

7.19e-07230220717166
Pubmed

Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal.

CREBBP EP300

7.19e-07230212397173
Pubmed

Differences in the interactions of oncogenic adenovirus 12 early region 1A and nononcogenic adenovirus 2 early region 1A with the cellular coactivators p300 and CBP.

CREBBP EP300

7.19e-07230210049825
Pubmed

CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding.

CREBBP EP300

7.19e-07230215641773
Pubmed

Single-stranded antisense siRNAs guide target RNA cleavage in RNAi.

AGO2 AGO1

7.19e-07230212230974
Pubmed

Association study of AGO1 and AGO2 genes polymorphisms with recurrent pregnancy loss.

AGO2 AGO1

7.19e-07230231666609
Pubmed

Differential contribution of p300 and CBP to regulatory element acetylation in mESCs.

CREBBP EP300

7.19e-07230232690000
Pubmed

Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 and CREB binding protein.

CREBBP EP300

7.19e-0723029733868
Pubmed

CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.

CREBBP EP300

7.19e-07230230953353
Pubmed

Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.

CREBBP EP300

7.19e-07230221803292
Pubmed

Mutations in SRCAP, encoding SNF2-related CREBBP activator protein, cause Floating-Harbor syndrome.

SRCAP CREBBP

7.19e-07230222265015
Pubmed

Effects of Echinococcus multilocularis miR-71 mimics on murine macrophage RAW264.7 cells.

AGO1 AGO4

7.19e-07230226995025
Pubmed

HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter.

CREBBP EP300

7.19e-0723029811832
Pubmed

CBP/p300 acetyltransferase activity in hematologic malignancies.

CREBBP EP300

7.19e-07230227380996
Pubmed

CREBBP and p300 lysine acetyl transferases in the DNA damage response.

CREBBP EP300

7.19e-07230229170789
Pubmed

Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.

CREBBP EP300

7.19e-07230224089570
Pubmed

The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.

CREBBP EP300

7.19e-07230225893291
Pubmed

Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.

CREBBP EP300

7.19e-07230211559821
Pubmed

Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.

CREBBP EP300

7.19e-07230221555743
Pubmed

Polymorphisms and expression of genes encoding Argonautes 1 and 2 in autoimmune thyroid diseases.

AGO2 AGO1

7.19e-07230229256262
Pubmed

Rubinstein-Taybi syndrome in Chinese population with four novel mutations.

CREBBP EP300

7.19e-07230233063428
Pubmed

CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells.

CREBBP EP300

7.19e-07230212646247
Pubmed

EP300/CBP is crucial for cAMP-PKA pathway to alleviate podocyte dedifferentiation via targeting Notch3 signaling.

CREBBP EP300

7.19e-07230234506759
InteractionTDRD1 interactions

AGO2 AGO1 AGO4 AGO3

1.52e-0819304int:TDRD1
InteractionTRIM24 interactions

MLKL AGO2 AGO1 AGO4 SRCAP AGO3 CREBBP EP300

8.63e-08398308int:TRIM24
InteractionHSP90AB4P interactions

AGO2 AGO1 AGO4 AGO3 USP11

1.11e-06126305int:HSP90AB4P
InteractionBMI1 interactions

HSF2BP PHF6 PTBP3 AGO2 AGO1 CREBBP USP11 EP300

3.88e-06659308int:BMI1
InteractionMARK1 interactions

AGO2 AGO1 AGO4 AGO3

4.27e-0674304int:MARK1
InteractionATOH1 interactions

AGO2 AGO1 AGO3 USP11

5.83e-0680304int:ATOH1
InteractionFAM120C interactions

ESRP2 PTBP3 AGO2 AGO1 AGO3

8.53e-06191305int:FAM120C
InteractionRBMS1 interactions

ESRP2 PTBP3 AGO2 AGO1 AGO3

1.26e-05207305int:RBMS1
InteractionCITED1 interactions

CREBBP USP11 EP300

2.24e-0537303int:CITED1
InteractionTARBP2 interactions

AGO2 AGO1 AGO4 AGO3

4.10e-05131304int:TARBP2
InteractionMARK2 interactions

AGO2 AGO1 AGO4 AGO3 CREBBP

4.83e-05274305int:MARK2
InteractionTNRC6C interactions

AGO2 AGO1 AGO4 AGO3

5.02e-05138304int:TNRC6C
InteractionPUM1 interactions

PTBP3 AGO2 AGO1 AGO3 EP300

6.02e-05287305int:PUM1
InteractionDAZL interactions

PTBP3 AGO2 AGO1 AGO3

6.09e-05145304int:DAZL
InteractionCELF1 interactions

ESRP2 PTBP3 AGO2 AGO1 AGO3

6.12e-05288305int:CELF1
InteractionHES6 interactions

ESRP2 CREBBP EP300

6.26e-0552303int:HES6
InteractionDECR2 interactions

ESRP2 USP11 EP300

7.01e-0554303int:DECR2
InteractionPEX5L interactions

AGO2 AGO1 AGO3

7.01e-0554303int:PEX5L
InteractionAGO3 interactions

AGO2 AGO1 AGO4 AGO3

7.51e-05153304int:AGO3
InteractionHOXB3 interactions

CREBBP EP300

7.66e-059302int:HOXB3
InteractionARGFX interactions

CREBBP EP300

7.66e-059302int:ARGFX
InteractionKLF4 interactions

HSF2BP CREBBP USP11 EP300

8.93e-05160304int:KLF4
InteractionHOXB6 interactions

CREBBP EP300 TRAPPC9

9.62e-0560303int:HOXB6
InteractionTP73 interactions

AGO2 AGO1 CREBBP EP300

1.10e-04169304int:TP73
InteractionPATL1 interactions

AGO2 AGO1 AGO3 EP300

1.32e-04177304int:PATL1
InteractionCNOT2 interactions

HSF2BP AGO2 AGO1 AGO3

1.35e-04178304int:CNOT2
InteractionDICER1 interactions

AGO2 AGO1 AGO4 AGO3

1.44e-04181304int:DICER1
InteractionZFP36 interactions

ESRP2 AGO2 AGO1 AGO3

1.44e-04181304int:ZFP36
InteractionTMEFF2 interactions

HSF2BP AGO2

1.65e-0413302int:TMEFF2
InteractionKAT5 interactions

HSF2BP AGO2 SRCAP CREBBP EP300

1.70e-04358305int:KAT5
InteractionIPO8 interactions

AGO2 AGO1 AGO4 AGO3

1.77e-04191304int:IPO8
InteractionGPBP1 interactions

HSF2BP CREBBP EP300

1.87e-0475303int:GPBP1
InteractionCTIF interactions

AGO2 AGO1 AGO3

2.02e-0477303int:CTIF
InteractionSEMA3B interactions

HSF2BP CREBBP USP11

2.10e-0478303int:SEMA3B
InteractionE2F1 interactions

CREBBP USP11 EP300 PRDM2

2.11e-04200304int:E2F1
InteractionHSF2 interactions

HSF2BP CREBBP EP300

2.18e-0479303int:HSF2
InteractionCIMAP1D interactions

HSF2BP TRAPPC9

2.22e-0415302int:CIMAP1D
InteractionKLF2 interactions

CREBBP EP300

2.22e-0415302int:KLF2
InteractionMKRN2 interactions

PTBP3 AGO2 AGO1 AGO3 EP300

2.38e-04385305int:MKRN2
InteractionSOX7 interactions

ADNP2 CREBBP EP300

2.44e-0482303int:SOX7
InteractionSRA1 interactions

MLKL AGO2 AGO1

2.52e-0483303int:SRA1
InteractionSP3 interactions

ADAMTS12 CREBBP EP300

2.61e-0484303int:SP3
InteractionH2AC25 interactions

HSF2BP CREBBP EP300

2.61e-0484303int:H2AC25
InteractionMAML2 interactions

CREBBP EP300

2.87e-0417302int:MAML2
InteractionHNRNPC interactions

PHF6 PTBP3 AGO2 AGO1 AGO4 EP300

2.95e-04634306int:HNRNPC
InteractionMEX3B interactions

AGO2 AGO1 AGO4 AGO3

3.14e-04222304int:MEX3B
InteractionDYRK1B interactions

CREBBP USP11 EP300

3.31e-0491303int:DYRK1B
InteractionCNOT6L interactions

AGO2 AGO1 AGO3

3.53e-0493303int:CNOT6L
InteractionHSP90AA5P interactions

AGO1 AGO4 AGO3

3.53e-0493303int:HSP90AA5P
InteractionNEUROG1 interactions

CREBBP EP300

3.61e-0419302int:NEUROG1
InteractionCTR9 interactions

AGO2 AGO4 USP11 EP300

3.77e-04233304int:CTR9
InteractionSPIB interactions

CREBBP EP300

4.00e-0420302int:SPIB
InteractionTP53BP2 interactions

ADAMTS12 HSF2BP CREBBP EP300

4.28e-04241304int:TP53BP2
InteractionHOXB4 interactions

CREBBP EP300

4.42e-0421302int:HOXB4
InteractionPLAGL1 interactions

CREBBP EP300

4.42e-0421302int:PLAGL1
InteractionKLF13 interactions

CREBBP EP300

4.42e-0421302int:KLF13
InteractionCITED4 interactions

CREBBP EP300

4.42e-0421302int:CITED4
InteractionGAPDH interactions

AGO2 AGO1 AGO4 AGO3 USP11 EP300

4.49e-04686306int:GAPDH
InteractionMARK3 interactions

AGO2 AGO1 AGO4 AGO3

4.63e-04246304int:MARK3
InteractionMOV10 interactions

ADNP2 PTBP3 AGO2 AGO1 AGO3 USP11 EP300 TRAPPC9

4.70e-041297308int:MOV10
InteractionDDB1 interactions

PHF6 AGO2 AGO1 CREBBP USP11 EP300

4.89e-04697306int:DDB1
InteractionCITED2 interactions

CREBBP EP300

5.32e-0423302int:CITED2
InteractionHOXD10 interactions

CREBBP EP300

5.32e-0423302int:HOXD10
InteractionHELZ interactions

AGO2 AGO1 AGO3 CREBBP

5.45e-04257304int:HELZ
InteractionCNTN2 interactions

CREBBP EP300

5.79e-0424302int:CNTN2
InteractionNR6A1 interactions

CREBBP EP300

5.79e-0424302int:NR6A1
InteractionTBX21 interactions

CREBBP EP300

5.79e-0424302int:TBX21
InteractionAGO2 interactions

PTBP3 AGO2 AGO1 AGO4 AGO3

6.06e-04472305int:AGO2
InteractionALX1 interactions

CREBBP EP300

6.29e-0425302int:ALX1
InteractionHNRNPU interactions

PHF6 AGO2 AGO1 AGO3 USP11 EP300 PRDM2

6.64e-041035307int:HNRNPU
InteractionHOXB7 interactions

CREBBP EP300

6.81e-0426302int:HOXB7
InteractionPGAM5 interactions

MLKL AGO4 USP11 EP300

6.93e-04274304int:PGAM5
InteractionAGO4 interactions

AGO2 AGO4 AGO3

7.08e-04118303int:AGO4
InteractionKIF20A interactions

PTBP3 ADGRL1 AGO2 AGO1 AGO4 AGO3 RPL3L

7.31e-041052307int:KIF20A
InteractionKBTBD8 interactions

AGO2 AGO4

7.35e-0427302int:KBTBD8
InteractionTNRC6A interactions

AGO2 AGO1 AGO4 AGO3

7.52e-04280304int:TNRC6A
InteractionETS1 interactions

SRCAP CREBBP EP300

7.61e-04121303int:ETS1
InteractionTNRC6B interactions

AGO2 AGO1 AGO4 AGO3

7.72e-04282304int:TNRC6B
InteractionDDX6 interactions

AGO2 AGO1 AGO4 AGO3 EP300

8.08e-04503305int:DDX6
InteractionPCBP2 interactions

PHF6 AGO2 AGO1 EP300

8.35e-04288304int:PCBP2
InteractionSRCAP interactions

SRCAP CREBBP EP300

8.76e-04127303int:SRCAP
InteractionSLC1A4 interactions

AGO2 CREBBP

9.08e-0430302int:SLC1A4
InteractionHOXD4 interactions

CREBBP EP300

9.08e-0430302int:HOXD4
InteractionR3HDM2 interactions

AGO2 AGO1 AGO3

9.17e-04129303int:R3HDM2
InteractionFUBP3 interactions

AGO2 AGO1 AGO3 EP300

9.36e-04297304int:FUBP3
InteractionUBAP2L interactions

ESRP2 AGO2 AGO1 AGO3

9.48e-04298304int:UBAP2L
InteractionFBXL9P interactions

ESRP2 HSF2BP

9.70e-0431302int:FBXL9P
InteractionCRTC1 interactions

CREBBP EP300

9.70e-0431302int:CRTC1
InteractionEIF4ENIF1 interactions

AGO2 AGO1 AGO3 CREBBP

9.72e-04300304int:EIF4ENIF1
InteractionMYB interactions

PHF6 CREBBP EP300

1.00e-03133303int:MYB
InteractionNEUROD1 interactions

CREBBP EP300

1.03e-0332302int:NEUROD1
InteractionPPARG interactions

AGO2 PPEF2 CREBBP EP300

1.06e-03307304int:PPARG
InteractionTRERF1 interactions

CREBBP EP300

1.10e-0333302int:TRERF1
InteractionYTHDF2 interactions

AGO2 AGO1 AGO3 CREBBP

1.12e-03312304int:YTHDF2
InteractionHNRNPH2 interactions

HSF2BP AGO1 LYST USP11

1.12e-03312304int:HNRNPH2
InteractionCNOT7 interactions

AGO2 AGO1 AGO3

1.16e-03140303int:CNOT7
InteractionHAND2 interactions

AGO2 EP300

1.17e-0334302int:HAND2
InteractionANKS1B interactions

HSF2BP CREBBP

1.17e-0334302int:ANKS1B
InteractionNCOA2 interactions

SRCAP CREBBP EP300

1.19e-03141303int:NCOA2
InteractionC3orf62 interactions

CREBBP EP300

1.24e-0335302int:C3orf62
Cytoband1p34

AGO4 AGO3

2.02e-04323021p34
CytobandEnsembl 112 genes in cytogenetic band chr1p34

AGO1 AGO4 AGO3

9.29e-04294303chr1p34
CytobandEnsembl 112 genes in cytogenetic band chr8q24

AGO2 HAS2 TRAPPC9

1.59e-03355303chr8q24
GeneFamilyArgonaute/PIWI family

AGO2 AGO1 AGO4 AGO3

1.15e-108224408
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

1.90e-0417222486
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

2.14e-041822291
GeneFamilyRNA binding motif containing

ESRP2 PTBP3

2.73e-02213222725
DrugTremorine dihydrochloride [300-68-5]; Up 200; 15uM; HL60; HG-U133A

HSF2BP ADGRL1 EP300 TRAPPC9 PRDM2

4.74e-061982951579_UP
DiseaseMenke-Hennekam syndrome

CREBBP EP300

9.99e-072302cv:C5681632
DiseaseRubinstein-Taybi syndrome (implicated_via_orthology)

CREBBP EP300

9.99e-072302DOID:1933 (implicated_via_orthology)
DiseaseRubinstein-Taybi syndrome

CREBBP EP300

9.99e-072302cv:C0035934
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

9.99e-072302C4551859
DiseaseRubinstein-Taybi syndrome (is_implicated_in)

CREBBP EP300

9.99e-072302DOID:1933 (is_implicated_in)
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

9.99e-072302180849
DiseaseRubinstein-Taybi syndrome due to CREBBP mutations

CREBBP EP300

9.99e-072302cv:C4551859
DiseaseRubinstein-Taybi Syndrome

CREBBP EP300

9.99e-072302C0035934
DiseaseAdenoid Cystic Carcinoma

SRCAP CREBBP EP300

1.43e-04100303C0010606
Diseasecongestive heart failure (is_implicated_in)

PHF6 EP300

3.45e-0427302DOID:6000 (is_implicated_in)
Diseaseattention deficit hyperactivity disorder (implicated_via_orthology)

ADGRL1 TRAPPC9

3.72e-0428302DOID:1094 (implicated_via_orthology)
DiseaseBladder Neoplasm

CREBBP EP300 PRDM2

3.86e-04140303C0005695
DiseaseMalignant neoplasm of urinary bladder

CREBBP EP300 PRDM2

3.95e-04141303C0005684
Diseaseprogression free survival, response to carboplatin, methylcobalamin deficiency type cblE, ovarian carcinoma

AGO2 HAS2

7.23e-0439302EFO_0001075, EFO_0004920, GO_0097328, MONDO_0009354
Diseaseepilepsy

IQCM SCN1A

7.99e-0441302EFO_0000474
DiseaseCarcinoma, Transitional Cell

CREBBP EP300

7.99e-0441302C0007138
DiseaseAdenocarcinoma of lung (disorder)

HK1 CREBBP EP300

1.18e-03206303C0152013
DiseaseSmall cell carcinoma of lung

CREBBP EP300

1.38e-0354302C0149925
DiseaseDiffuse Large B-Cell Lymphoma

CREBBP EP300

1.44e-0355302C0079744
Diseaseacute lymphoblastic leukemia (is_implicated_in)

HK1 CREBBP

1.44e-0355302DOID:9952 (is_implicated_in)
DiseasePrecursor Cell Lymphoblastic Leukemia Lymphoma

CREBBP EP300

1.76e-0361302C1961102

Protein segments in the cluster

PeptideGeneStartEntry
MKRVVQHTKGCKRKT

EP300

1761

Q09472
KIKMRIGHTVAKQVY

CFAP54

2556

Q96N23
MHKRERTCKDYIKAV

ADGRL1

606

O94910
EVTHCGQMKRKYRVC

AGO1

266

Q9UL18
QKMKRVVQHTKGCKR

CREBBP

1796

Q92793
LKVEVTHCGTMRRKY

AGO3

266

Q9H9G7
KVEVTHCGQMKRKYR

AGO4

256

Q9HCK5
RQTAHCIKKGRGMVK

ADAMTS12

846

P58397
KVEITHCGQMKRKYR

AGO2

266

Q9UKV8
FGKRRYICMKAIKNH

ADNP2

1091

Q6IQ32
IRERKMRQHYKSCKV

IQCM

486

A0A1B0GVH7
VHGKVLLMQKYRRCG

HEXD

231

Q8WVB3
RSGKKRTVEMHNKIY

HK1

546

P19367
GQVIHKRCEEMKYCK

MLKL

11

Q8NB16
KCGRRKKGQQYDMVL

HAS2

536

Q92819
QKRYRGHKITHKMIC

F11

546

P03951
ERKKVIQHIRGMYKV

LYST

2901

Q99698
KYCKKVFGTHTNMRR

PRDM2

486

Q13029
VMNKYKVHGKEILRT

PPEF2

256

O14830
CRHMGTKEEFVKVRK

HSF2BP

11

O75031
AAMKKYCKVIRVIVH

RPL3L

151

Q92901
KVHNYCNMKKSRLGR

WT1-AS

26

Q06250
QRCHKKVMKERYVEV

ESRP2

536

Q9H6T0
EKQMPKKYEHVIRCR

SRCAP

846

Q6ZRS2
VDRMHKGVAYVKRKI

SCN1A

1016

P35498
QGIYMVYCRKHKKTA

PHF6

121

Q8IWS0
KSKHGKQRAEYMRIQ

SRCIN1

1121

Q9C0H9
VYGDVHRVKIMFNKK

PTBP3

381

O95758
HYKKRCQGRMRKHVG

TRAPPC9

196

Q96Q05
KHDCVGYVMKKAPVR

USP11

766

P51784