Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane transporter activity	CACNA1A CACNA1B ANO5 TRPV3 KCNK13 ATP13A3 SLC5A8 SLC25A19 SLC16A2 ZDHHC13 SLC2A2 CFTR	1.51e-06	1180	39	12	GO:0022857
GeneOntologyMolecularFunction	transporter activity	CACNA1A CACNA1B ANO5 TRPV3 KCNK13 ATP13A3 SLC5A8 SLC25A19 SLC16A2 ZDHHC13 SLC2A2 CFTR	3.80e-06	1289	39	12	GO:0005215
GeneOntologyMolecularFunction	corticotropin-releasing hormone receptor activity	CRHR1 CRHR2	1.11e-05	3	39	2	GO:0043404
GeneOntologyMolecularFunction	corticotrophin-releasing factor receptor activity	CRHR1 CRHR2	1.11e-05	3	39	2	GO:0015056
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	CACNA1A CACNA1B ANO5 TRPV3 KCNK13 ATP13A3 SLC5A8 ZDHHC13 CFTR	1.70e-05	793	39	9	GO:0015075
GeneOntologyMolecularFunction	amide binding	CACNA1A CACNA1B CRHR1 PTH2R CRHR2 SOAT1	2.31e-05	299	39	6	GO:0033218
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR10A2 OR52A4P OR6S1 OR5I1 CRHR1 PTH2R CRHR2 OR6J1 OR10A5	4.01e-05	884	39	9	GO:0004930
GeneOntologyMolecularFunction	passive transmembrane transporter activity	CACNA1A CACNA1B ANO5 TRPV3 KCNK13 SLC5A8 CFTR	6.26e-05	526	39	7	GO:0022803
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	CACNA1A CACNA1B ANO5 TRPV3 KCNK13 SLC5A8 ZDHHC13 CFTR	8.99e-05	758	39	8	GO:0015318
GeneOntologyMolecularFunction	RNA polymerase I general transcription initiation factor activity	RRN3P1 RRN3	1.33e-04	9	39	2	GO:0001181
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels	CACNA1A CACNA1B	1.33e-04	9	39	2	GO:0099511
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	CACNA1A CACNA1B	1.33e-04	9	39	2	GO:0099626
GeneOntologyMolecularFunction	peptide hormone binding	CRHR1 PTH2R CRHR2	1.68e-04	55	39	3	GO:0017046
GeneOntologyMolecularFunction	olfactory receptor activity	OR10A2 OR52A4P OR6S1 OR5I1 OR6J1 OR10A5	1.74e-04	431	39	6	GO:0004984
GeneOntologyMolecularFunction	monoatomic ion channel activity	CACNA1A CACNA1B ANO5 TRPV3 KCNK13 CFTR	2.45e-04	459	39	6	GO:0005216
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	SLC5A8 SLC25A19 SLC16A2 SLC2A2 CFTR	2.52e-04	293	39	5	GO:0008514
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	CACNA1A CACNA1B TRPV3 KCNK13 SLC5A8 ZDHHC13	2.62e-04	465	39	6	GO:0046873
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	CACNA1A CACNA1B TRPV3 KCNK13 ATP13A3 SLC5A8 ZDHHC13	2.65e-04	664	39	7	GO:0008324
GeneOntologyMolecularFunction	high voltage-gated calcium channel activity	CACNA1A CACNA1B	3.33e-04	14	39	2	GO:0008331
GeneOntologyMolecularFunction	gated channel activity	CACNA1A CACNA1B ANO5 KCNK13 CFTR	4.59e-04	334	39	5	GO:0022836
GeneOntologyMolecularFunction	channel activity	CACNA1A CACNA1B ANO5 TRPV3 KCNK13 CFTR	5.01e-04	525	39	6	GO:0015267
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR10A2 OR52A4P OR6S1 OR5I1 CRHR1 PTH2R CRHR2 OR6J1 OR10A5	9.72e-04	1353	39	9	GO:0004888
GeneOntologyMolecularFunction	hormone binding	CRHR1 PTH2R CRHR2	1.06e-03	103	39	3	GO:0042562
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	CACNA1A CACNA1B TRPV3 KCNK13 SLC5A8 ZDHHC13	1.26e-03	627	39	6	GO:0022890
GeneOntologyMolecularFunction	calcium channel activity	CACNA1A CACNA1B TRPV3	2.03e-03	129	39	3	GO:0005262
GeneOntologyMolecularFunction	G protein-coupled peptide receptor activity	CRHR1 PTH2R CRHR2	2.22e-03	133	39	3	GO:0008528
GeneOntologyMolecularFunction	active transmembrane transporter activity	ATP13A3 SLC5A8 SLC25A19 SLC16A2 CFTR	2.24e-03	477	39	5	GO:0022804
GeneOntologyMolecularFunction	vitamin transmembrane transporter activity	SLC25A19 SLC2A2	2.25e-03	36	39	2	GO:0090482
GeneOntologyMolecularFunction	peptide receptor activity	CRHR1 PTH2R CRHR2	2.56e-03	140	39	3	GO:0001653
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	CACNA1A CACNA1B TRPV3	3.17e-03	151	39	3	GO:0015085
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	CACNA1A CACNA1B KCNK13	3.23e-03	152	39	3	GO:0022843
GeneOntologyMolecularFunction	voltage-gated calcium channel activity	CACNA1A CACNA1B	3.64e-03	46	39	2	GO:0005245
GeneOntologyMolecularFunction	ABC-type transporter activity	ATP13A3 CFTR	4.13e-03	49	39	2	GO:0140359
GeneOntologyMolecularFunction	ligand-gated monoatomic anion channel activity	ANO5 CFTR	4.29e-03	50	39	2	GO:0099095
GeneOntologyMolecularFunction	monoatomic cation channel activity	CACNA1A CACNA1B TRPV3 KCNK13	4.38e-03	343	39	4	GO:0005261
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	CACNA1A CACNA1B KCNK13	5.35e-03	182	39	3	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	CACNA1A CACNA1B KCNK13	5.51e-03	184	39	3	GO:0022832
GeneOntologyMolecularFunction	O-acyltransferase activity	AWAT1 SOAT1	5.93e-03	59	39	2	GO:0008374
GeneOntologyMolecularFunction	general transcription initiation factor activity	RRN3P1 RRN3	7.81e-03	68	39	2	GO:0140223
GeneOntologyMolecularFunction	acyltransferase activity, transferring groups other than amino-acyl groups	ZDHHC13 AWAT1 SOAT1	1.11e-02	238	39	3	GO:0016747
GeneOntologyMolecularFunction	organic cation transmembrane transporter activity	ATP13A3 SLC25A19	1.14e-02	83	39	2	GO:0015101
GeneOntologyMolecularFunction	chloride channel activity	ANO5 CFTR	1.23e-02	86	39	2	GO:0005254
GeneOntologyMolecularFunction	monocarboxylic acid transmembrane transporter activity	SLC5A8 SLC16A2	1.34e-02	90	39	2	GO:0008028
GeneOntologyBiologicalProcess	organic cation transport	CACNA1A ATP13A3 SLC25A19 CRHR1 CRHR2	8.65e-06	145	40	5	GO:0015695
GeneOntologyBiologicalProcess	calcium ion import	CACNA1A CACNA1B TRPV3 CRHR2	3.84e-05	98	40	4	GO:0070509
GeneOntologyBiologicalProcess	monoatomic ion transport	CACNA1A CACNA1B ANO5 TRPV3 KCNK13 ATP13A3 SLC5A8 ZDHHC13 CRHR1 CRHR2 CFTR	4.21e-05	1374	40	11	GO:0006811
GeneOntologyBiologicalProcess	monoatomic cation transport	CACNA1A CACNA1B TRPV3 KCNK13 ATP13A3 SLC5A8 ZDHHC13 CRHR1 CRHR2 CFTR	5.36e-05	1157	40	10	GO:0006812
GeneOntologyBiologicalProcess	cellular response to corticotropin-releasing hormone stimulus	CRHR1 CRHR2	5.47e-05	6	40	2	GO:0071376
GeneOntologyBiologicalProcess	response to corticotropin-releasing hormone	CRHR1 CRHR2	5.47e-05	6	40	2	GO:0043435
GeneOntologyBiologicalProcess	detection of stimulus	OR10A2 OR52A4P OR6S1 SEMA5B OR5I1 CDS2 OR6J1 OR10A5	6.18e-05	722	40	8	GO:0051606
GeneOntologyBiologicalProcess	metal ion transport	CACNA1A CACNA1B TRPV3 KCNK13 SLC5A8 ZDHHC13 CRHR1 CRHR2 CFTR	1.00e-04	1000	40	9	GO:0030001
GeneOntologyBiologicalProcess	calcium ion import across plasma membrane	CACNA1A CACNA1B TRPV3	1.10e-04	48	40	3	GO:0098703
GeneOntologyBiologicalProcess	calcium ion import into cytosol	CACNA1A CACNA1B TRPV3	1.10e-04	48	40	3	GO:1902656
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	CACNA1A CACNA1B ANO5 TRPV3 KCNK13 SLC5A8 ZDHHC13 CRHR1 CFTR	1.14e-04	1017	40	9	GO:0098660
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR10A2 OR52A4P OR6S1 SEMA5B OR5I1 OR6J1 OR10A5	1.14e-04	582	40	7	GO:0050906
GeneOntologyBiologicalProcess	response to pain	CACNA1A CACNA1B CRHR1	1.32e-04	51	40	3	GO:0048265
GeneOntologyBiologicalProcess	negative regulation of epinephrine secretion	CRHR1 CRHR2	1.63e-04	10	40	2	GO:0032811
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR10A2 OR52A4P OR6S1 OR5I1 OR6J1 OR10A5	1.71e-04	432	40	6	GO:0050911
GeneOntologyBiologicalProcess	regulation of epinephrine secretion	CRHR1 CRHR2	1.99e-04	11	40	2	GO:0014060
GeneOntologyBiologicalProcess	response to amyloid-beta	CACNA1A CACNA1B MMP3	2.25e-04	61	40	3	GO:1904645
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	CACNA1A CACNA1B ANO5 TRPV3 KCNK13 ATP13A3 ZDHHC13 CRHR1 CFTR	2.28e-04	1115	40	9	GO:0034220
GeneOntologyBiologicalProcess	signal release	CACNA1A CACNA1B SLC16A2 CRHR1 SLC2A2 CRHR2 CFTR	2.32e-04	653	40	7	GO:0023061
GeneOntologyBiologicalProcess	sensory perception of smell	OR10A2 OR52A4P OR6S1 OR5I1 OR6J1 OR10A5	2.55e-04	465	40	6	GO:0007608
GeneOntologyBiologicalProcess	epinephrine secretion	CRHR1 CRHR2	2.82e-04	13	40	2	GO:0048242
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR10A2 OR52A4P OR6S1 OR5I1 OR6J1 OR10A5	3.19e-04	485	40	6	GO:0050907
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	CACNA1A CACNA1B TRPV3 KCNK13 ATP13A3 ZDHHC13 CRHR1 CFTR	3.84e-04	942	40	8	GO:0098655
GeneOntologyBiologicalProcess	organic anion transport	CACNA1A SLC5A8 SLC25A19 SLC16A2 SLC2A2 CFTR	4.39e-04	515	40	6	GO:0015711
GeneOntologyBiologicalProcess	peptide hormone secretion	SLC16A2 CRHR1 SLC2A2 CRHR2 CFTR	4.47e-04	334	40	5	GO:0030072
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR10A2 OR52A4P OR6S1 OR5I1 OR6J1 OR10A5	4.81e-04	524	40	6	GO:0009593
GeneOntologyBiologicalProcess	epinephrine transport	CRHR1 CRHR2	4.90e-04	17	40	2	GO:0048241
GeneOntologyBiologicalProcess	peptide secretion	SLC16A2 CRHR1 SLC2A2 CRHR2 CFTR	5.04e-04	343	40	5	GO:0002790
GeneOntologyBiologicalProcess	transcription initiation at RNA polymerase I promoter	RRN3P1 RRN3	5.50e-04	18	40	2	GO:0006361
GeneOntologyBiologicalProcess	peptide transport	SLC16A2 CRHR1 SLC2A2 CRHR2 CFTR	5.89e-04	355	40	5	GO:0015833
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR10A2 OR52A4P OR6S1 OR5I1 OR6J1 OR10A5	6.03e-04	547	40	6	GO:0007606
GeneOntologyBiologicalProcess	organic hydroxy compound transport	SLC5A8 CRHR1 CRHR2 SOAT1 CFTR	6.12e-04	358	40	5	GO:0015850
GeneOntologyBiologicalProcess	regulation of insulin secretion involved in cellular response to glucose stimulus	SLC2A2 CRHR2 CFTR	7.53e-04	92	40	3	GO:0061178
GeneOntologyBiologicalProcess	secretion by cell	CACNA1A CACNA1B SLC16A2 SCAMP1 CRHR1 SLC2A2 CRHR2 CFTR	8.59e-04	1064	40	8	GO:0032940
GeneOntologyBiologicalProcess	negative regulation of catecholamine secretion	CRHR1 CRHR2	9.04e-04	23	40	2	GO:0033604
GeneOntologyBiologicalProcess	positive regulation of cAMP-mediated signaling	CRHR1 CRHR2	9.04e-04	23	40	2	GO:0043950
GeneOntologyBiologicalProcess	import across plasma membrane	CACNA1A CACNA1B TRPV3 SLC16A2	1.00e-03	230	40	4	GO:0098739
GeneOntologyBiologicalProcess	insulin secretion involved in cellular response to glucose stimulus	SLC2A2 CRHR2 CFTR	1.02e-03	102	40	3	GO:0035773
GeneOntologyBiologicalProcess	positive regulation of secretion by cell	CACNA1B CRHR1 SLC2A2 CRHR2 CFTR	1.05e-03	404	40	5	GO:1903532
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR10A2 OR52A4P OR6S1 OR5I1 CRHR1 PTH2R CRHR2 OR6J1 OR10A5	1.16e-03	1395	40	9	GO:0007186
GeneOntologyBiologicalProcess	hormone secretion	SLC16A2 CRHR1 SLC2A2 CRHR2 CFTR	1.25e-03	420	40	5	GO:0046879
GeneOntologyBiologicalProcess	amide transport	SLC16A2 CRHR1 SLC2A2 CRHR2 CFTR	1.25e-03	420	40	5	GO:0042886
GeneOntologyBiologicalProcess	hormone transport	SLC16A2 CRHR1 SLC2A2 CRHR2 CFTR	1.42e-03	432	40	5	GO:0009914
GeneOntologyBiologicalProcess	export from cell	CACNA1A CACNA1B SLC16A2 SCAMP1 CRHR1 SLC2A2 CRHR2 CFTR	1.44e-03	1153	40	8	GO:0140352
GeneOntologyBiologicalProcess	exocytosis	CACNA1A CACNA1B SCAMP1 CRHR1 CFTR	1.45e-03	434	40	5	GO:0006887
GeneOntologyBiologicalProcess	positive regulation of secretion	CACNA1B CRHR1 SLC2A2 CRHR2 CFTR	1.46e-03	435	40	5	GO:0051047
GeneOntologyBiologicalProcess	behavioral response to pain	CACNA1A CRHR1	1.75e-03	32	40	2	GO:0048266
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	CACNA1A CACNA1B TRPV3 KCNK13 ZDHHC13 CRHR1 CFTR	1.79e-03	922	40	7	GO:0098662
GeneOntologyBiologicalProcess	regulation of amine transport	CACNA1A CRHR1 CRHR2	1.82e-03	125	40	3	GO:0051952
GeneOntologyBiologicalProcess	negative regulation of feeding behavior	CRHR1 CRHR2	1.86e-03	33	40	2	GO:2000252
GeneOntologyBiologicalProcess	multicellular organismal response to stress	CACNA1A CACNA1B CRHR1	1.86e-03	126	40	3	GO:0033555
GeneOntologyBiologicalProcess	regulation of hormone levels	CACNA1A SLC16A2 CRHR1 SLC2A2 CRHR2 CFTR	1.91e-03	684	40	6	GO:0010817
GeneOntologyBiologicalProcess	chloride transport	ANO5 SLC5A8 CFTR	1.95e-03	128	40	3	GO:0006821
GeneOntologyBiologicalProcess	secretion	CACNA1A CACNA1B SLC16A2 SCAMP1 CRHR1 SLC2A2 CRHR2 CFTR	2.07e-03	1221	40	8	GO:0046903
GeneOntologyBiologicalProcess	inorganic anion transmembrane transport	ANO5 SLC5A8 CFTR	2.22e-03	134	40	3	GO:0098661
GeneOntologyBiologicalProcess	amine transport	CACNA1A CRHR1 CRHR2	2.37e-03	137	40	3	GO:0015837
GeneOntologyBiologicalProcess	inorganic ion import across plasma membrane	CACNA1A CACNA1B TRPV3	2.62e-03	142	40	3	GO:0099587
GeneOntologyBiologicalProcess	phenol-containing compound metabolic process	RNF180 SLC16A2 CRHR2	2.62e-03	142	40	3	GO:0018958
GeneOntologyBiologicalProcess	inorganic cation import across plasma membrane	CACNA1A CACNA1B TRPV3	2.62e-03	142	40	3	GO:0098659
GeneOntologyBiologicalProcess	regulation of cAMP-mediated signaling	CRHR1 CRHR2	2.73e-03	40	40	2	GO:0043949
GeneOntologyBiologicalProcess	regulation of secretion by cell	CACNA1A CACNA1B CRHR1 SLC2A2 CRHR2 CFTR	2.83e-03	740	40	6	GO:1903530
GeneOntologyBiologicalProcess	calcium ion transport	CACNA1A CACNA1B TRPV3 CRHR1 CRHR2	2.90e-03	509	40	5	GO:0006816
GeneOntologyBiologicalProcess	negative regulation of amine transport	CRHR1 CRHR2	3.15e-03	43	40	2	GO:0051953
GeneOntologyCellularComponent	endoplasmic reticulum membrane	ANO5 RNF180 ALOX5AP AWAT1 MACO1 SOAT1 CFTR CDS2 TMEM147	5.04e-04	1293	39	9	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	ANO5 RNF180 ALOX5AP AWAT1 MACO1 SOAT1 CFTR CDS2 TMEM147	5.21e-04	1299	39	9	GO:0098827
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	ANO5 RNF180 ALOX5AP AWAT1 MACO1 SOAT1 CFTR CDS2 TMEM147	6.09e-04	1327	39	9	GO:0042175
GeneOntologyCellularComponent	apical part of cell	MAL2 SLC5A8 SLC16A2 CRHR1 SLC2A2 CFTR	7.41e-04	592	39	6	GO:0045177
GeneOntologyCellularComponent	recycling endosome membrane	ATP13A3 SCAMP1 CFTR	1.19e-03	112	39	3	GO:0055038
GeneOntologyCellularComponent	apical plasma membrane	MAL2 SLC5A8 SLC16A2 SLC2A2 CFTR	2.01e-03	487	39	5	GO:0016324
Domain	GPCR_2_CRF_rcpt	CRHR1 CRHR2	1.21e-05	3	38	2	IPR003051
Domain	HormR	CRHR1 PTH2R CRHR2	1.73e-05	25	38	3	SM00008
Domain	HRM	CRHR1 PTH2R CRHR2	2.46e-05	28	38	3	PF02793
Domain	GPCR_2_secretin-like_CS	CRHR1 PTH2R CRHR2	4.45e-05	34	38	3	IPR017983
Domain	G_PROTEIN_RECEP_F2_1	CRHR1 PTH2R CRHR2	7.29e-05	40	38	3	PS00649
Domain	G_PROTEIN_RECEP_F2_3	CRHR1 PTH2R CRHR2	7.29e-05	40	38	3	PS50227
Domain	GPCR_2_extracellular_dom	CRHR1 PTH2R CRHR2	7.29e-05	40	38	3	IPR001879
Domain	GPHH_dom	CACNA1A CACNA1B	8.41e-05	7	38	2	IPR031649
Domain	VDCC_a1su_IQ	CACNA1A CACNA1B	8.41e-05	7	38	2	IPR014873
Domain	Ca_chan_IQ	CACNA1A CACNA1B	8.41e-05	7	38	2	SM01062
Domain	Ca_chan_IQ	CACNA1A CACNA1B	8.41e-05	7	38	2	PF08763
Domain	GPHH	CACNA1A CACNA1B	8.41e-05	7	38	2	PF16905
Domain	Olfact_rcpt	OR10A2 OR52A4P OR6S1 OR5I1 OR6J1 OR10A5	1.30e-04	393	38	6	IPR000725
Domain	G_PROTEIN_RECEP_F2_2	CRHR1 PTH2R CRHR2	1.43e-04	50	38	3	PS00650
Domain	7tm_2	CRHR1 PTH2R CRHR2	1.43e-04	50	38	3	PF00002
Domain	VDCCAlpha1	CACNA1A CACNA1B	1.80e-04	10	38	2	IPR002077
Domain	GPCR_2-like	CRHR1 PTH2R CRHR2	2.45e-04	60	38	3	IPR017981
Domain	GPCR_2_secretin-like	CRHR1 PTH2R CRHR2	2.45e-04	60	38	3	IPR000832
Domain	G_PROTEIN_RECEP_F2_4	CRHR1 PTH2R CRHR2	2.58e-04	61	38	3	PS50261
Domain	Ion_trans_dom	CACNA1A CACNA1B TRPV3	1.60e-03	114	38	3	IPR005821
Domain	Ion_trans	CACNA1A CACNA1B TRPV3	1.60e-03	114	38	3	PF00520
Domain	7tm_1	OR10A2 OR52A4P OR6S1 OR5I1 OR6J1 OR10A5	2.28e-03	677	38	6	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR10A2 OR52A4P OR6S1 OR5I1 OR6J1 OR10A5	2.41e-03	685	38	6	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR10A2 OR52A4P OR6S1 OR5I1 OR6J1 OR10A5	2.52e-03	691	38	6	PS50262
Domain	GPCR_Rhodpsn	OR10A2 OR52A4P OR6S1 OR5I1 OR6J1 OR10A5	2.54e-03	692	38	6	IPR000276
Domain	Channel_four-helix_dom	CACNA1A CACNA1B	6.00e-03	57	38	2	IPR027359
Domain	-	CACNA1A CACNA1B	6.00e-03	57	38	2	1.20.120.350
Domain	GPCR_Rhodpsn_7TM	OR10A2 OR52A4P OR6S1 OR5I1 OR10A5	1.10e-02	670	38	5	IPR017452
Pathway	WP_GPCRS_CLASS_B_SECRETINLIKE	CRHR1 PTH2R CRHR2	1.89e-05	24	31	3	MM15992
Pathway	WP_GPCRS_CLASS_B_SECRETINLIKE	CRHR1 PTH2R CRHR2	1.89e-05	24	31	3	M39643
Pathway	KEGG_TYPE_II_DIABETES_MELLITUS	CACNA1A CACNA1B SLC2A2	1.46e-04	47	31	3	M19708
Pathway	KEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY	CACNA1A CACNA1B	2.54e-04	11	31	2	M47958
Pathway	REACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING	CACNA1A CACNA1B	2.54e-04	11	31	2	MM14498
Pathway	REACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING	CACNA1A CACNA1B	2.54e-04	11	31	2	M26913
Pathway	REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS	CRHR1 PTH2R CRHR2	3.03e-04	60	31	3	MM14964
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	ANO5 TRPV3 SLC5A8 SLC16A2 SLC2A2 SOAT1 CFTR	5.66e-04	681	31	7	MM14985
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	ANO5 TRPV3 SLC5A8 SLC16A2 SLC2A2 SOAT1 CFTR	8.99e-04	736	31	7	M27287
Pathway	WP_TYPE_II_DIABETES_MELLITUS	CACNA1A SLC2A2	1.05e-03	22	31	2	M39658
Pathway	REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS	CRHR1 PTH2R CRHR2	1.13e-03	94	31	3	M797
Pathway	KEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY	CACNA1A CACNA1B	1.15e-03	23	31	2	M47666
Pathway	KEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL	CACNA1A CACNA1B	1.36e-03	25	31	2	M47948
Pathway	KEGG_MEDICUS_REFERENCE_CRHR_PKA_ACTH_SIGNALING_PATHWAY	CRHR1 CRHR2	1.59e-03	27	31	2	M47518
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR10A2 OR6S1 OR5I1 OR6J1 OR10A5	1.99e-03	417	31	5	M4072
Pubmed	Expression and subcellular localization of CRH and its receptors in human endometrial cancer.	CRHR1 CRHR2	1.36e-06	2	41	2	19433256
Pubmed	Molecular mechanisms of corticotropin-releasing factor receptor-induced calcium signaling.	CRHR1 CRHR2	1.36e-06	2	41	2	19098121
Pubmed	Stable respiratory activity requires both P/Q-type and N-type voltage-gated calcium channels.	CACNA1A CACNA1B	1.36e-06	2	41	2	23426690
Pubmed	Corticotropin-releasing factor receptors induce calcium mobilization through cross-talk with Gq-coupled receptors.	CRHR1 CRHR2	1.36e-06	2	41	2	20594969
Pubmed	Novel corticotropin-releasing hormone receptor genes (CRHR1 and CRHR2) linkage to and association with polycystic ovary syndrome.	CRHR1 CRHR2	1.36e-06	2	41	2	37543650
Pubmed	Association of CRHR1 and CRHR2 with major depressive disorder and panic disorder in a Japanese population.	CRHR1 CRHR2	1.36e-06	2	41	2	22467522
Pubmed	Dysregulation of bladder corticotropin-releasing hormone receptor in the pathogenesis of human interstitial cystitis/bladder pain syndrome.	CRHR1 CRHR2	1.36e-06	2	41	2	31844086
Pubmed	Corticotropin-releasing hormone receptor (CRHR)1 and CRHR2 are both trafficking and signaling receptors for urocortin.	CRHR1 CRHR2	1.36e-06	2	41	2	17170072
Pubmed	Genetic variation in the corticotrophin-releasing factor receptors: identification of single-nucleotide polymorphisms and association studies with obesity in UK Caucasians.	CRHR1 CRHR2	1.36e-06	2	41	2	14724656
Pubmed	Synthetic Aβ oligomers (Aβ(1-42) globulomer) modulate presynaptic calcium currents: prevention of Aβ-induced synaptic deficits by calcium channel blockers.	CACNA1A CACNA1B	1.36e-06	2	41	2	23376566
Pubmed	Expression of corticotropin-releasing hormone receptor type 1 and type 2 in human pregnant myometrium.	CRHR1 CRHR2	1.36e-06	2	41	2	17959885
Pubmed	Differential regulation of prostaglandin production mediated by corticotropin-releasing hormone receptor type 1 and type 2 in cultured human placental trophoblasts.	CRHR1 CRHR2	1.36e-06	2	41	2	18325997
Pubmed	Association study between the corticotropin-releasing hormone receptor 2 gene and suicidality in bipolar disorder.	CRHR1 CRHR2	1.36e-06	2	41	2	17532191
Pubmed	The highly selective CRF(2) receptor antagonist K41498 binds to presynaptic CRF(2) receptors in rat brain.	CRHR1 CRHR2	1.36e-06	2	41	2	12110614
Pubmed	HPA axis genes may modulate the effect of childhood adversities on decision-making in suicide attempters.	CRHR1 CRHR2	1.36e-06	2	41	2	23177644
Pubmed	Different effects of chronic social defeat on social behavior and the brain CRF system in adult male C57 mice with different susceptibilities.	CRHR1 CRHR2	1.36e-06	2	41	2	32057826
Pubmed	Distinct distribution of corticotropin releasing factor receptors in human breast cancer.	CRHR1 CRHR2	1.36e-06	2	41	2	20630588
Pubmed	Effect of CRHR1 and CRHR2 gene polymorphisms and childhood trauma in suicide attempt.	CRHR1 CRHR2	1.36e-06	2	41	2	30874897
Pubmed	Expression and functional characterization of membrane-integrated mammalian corticotropin releasing factor receptors 1 and 2 in Escherichia coli.	CRHR1 CRHR2	1.36e-06	2	41	2	24465390
Pubmed	CaV 2.1 α1 subunit motifs that control presynaptic CaV 2.1 subtype abundance are distinct from CaV 2.1 preference.	CACNA1A CACNA1B	1.36e-06	2	41	2	38155373
Pubmed	Expression analysis of P/Q-type Ca2+ channel alpha 1A subunit mRNA in olfactory mitral cell in N-type Ca2+ channel alpha 1B subunit gene-deficient mice.	CACNA1A CACNA1B	1.36e-06	2	41	2	15050706
Pubmed	Association between corticotropin-releasing hormone receptor 1 and 2 (CRHR1 and CRHR2) gene polymorphisms and personality traits.	CRHR1 CRHR2	1.36e-06	2	41	2	23982282
Pubmed	Ethanol concentration-dependent effects and the role of stress on ethanol drinking in corticotropin-releasing factor type 1 and double type 1 and 2 receptor knockout mice.	CRHR1 CRHR2	1.36e-06	2	41	2	21487655
Pubmed	Corticotropin-Releasing Hormone Family and Their Receptors in the Cardiovascular System.	CRHR1 CRHR2	1.36e-06	2	41	2	30584229
Pubmed	Corticotropin-releasing hormone receptor expression on normal and tumorous human adrenocortical cells.	CRHR1 CRHR2	1.36e-06	2	41	2	16721033
Pubmed	Estrogen alters the splicing of type 1 corticotropin-releasing hormone receptor in breast cancer cells.	CRHR1 CRHR2	1.36e-06	2	41	2	23821771
Pubmed	Corticotropin-releasing hormone family of peptides regulates intestinal angiogenesis.	CRHR1 CRHR2	4.06e-06	3	41	2	20206175
Pubmed	Corticotropin-releasing hormone receptor type 1 and type 2 mediate differential effects on 15-hydroxy prostaglandin dehydrogenase expression in cultured human chorion trophoblasts.	CRHR1 CRHR2	4.06e-06	3	41	2	17463062
Pubmed	Corticotropin releasing hormone receptor alterations elicited by acute and chronic unpredictable stressor challenges in stressor-susceptible and resilient strains of mice.	CRHR1 CRHR2	4.06e-06	3	41	2	17517441
Pubmed	Corticotropin-releasing hormone receptor-1 in cerebral microvessels changes during development and influences urocortin transport across the blood-brain barrier.	CRHR1 CRHR2	4.06e-06	3	41	2	20032050
Pubmed	The CRF1 and the CRF2 receptor mediate recognition memory deficits and vulnerability induced by opiate withdrawal.	CRHR1 CRHR2	4.06e-06	3	41	2	26907806
Pubmed	Munc13-3 Is Required for the Developmental Localization of Ca2+ Channels to Active Zones and the Nanopositioning of Cav2.1 Near Release Sensors.	CACNA1A CACNA1B	4.06e-06	3	41	2	29466725
Pubmed	CRF1 and CRF2 receptors are required for potentiated startle to contextual but not discrete cues.	CRHR1 CRHR2	4.06e-06	3	41	2	19020499
Pubmed	Corticotropin-releasing factor receptors CRF1 and CRF2 exert both additive and opposing influences on defensive startle behavior.	CRHR1 CRHR2	4.06e-06	3	41	2	15269266
Pubmed	Reduced cerebral injury in CRH-R1 deficient mice after focal ischemia: a potential link to microglia and atrocytes that express CRH-R1.	CRHR1 CRHR2	4.06e-06	3	41	2	14526225
Pubmed	Ankyrin-B regulates Cav2.1 and Cav2.2 channel expression and targeting.	CACNA1A CACNA1B	4.06e-06	3	41	2	24394417
Pubmed	Regulation of the hypothalamic-pituitary-adrenocortical system in mice deficient for CRH receptors 1 and 2.	CRHR1 CRHR2	4.06e-06	3	41	2	11606463
Pubmed	Consolidation of remote fear memories involves Corticotropin-Releasing Hormone (CRH) receptor type 1-mediated enhancement of AMPA receptor GluR1 signaling in the dentate gyrus.	CRHR1 CRHR2	4.06e-06	3	41	2	22030710
Pubmed	DNA methylation of HPA-axis genes and the onset of major depressive disorder in adolescent girls: a prospective analysis.	CRHR1 CRHR2	4.06e-06	3	41	2	31582756
Pubmed	The role of hypothalamus-pituitary-adrenal genes and childhood trauma in borderline personality disorder.	CRHR1 CRHR2	4.06e-06	3	41	2	26182893
Pubmed	Corticotropin-releasing hormone receptor-1 and 2 activity produces divergent resistance against stress-induced pulmonary Streptococcus pneumoniae infection.	CRHR1 CRHR2	4.06e-06	3	41	2	21774994
Pubmed	Lipopolysaccharide-induced tau phosphorylation and kinase activity--modulation, but not mediation, by corticotropin-releasing factor receptors.	CRHR1 CRHR2	4.06e-06	3	41	2	21722209
Pubmed	The effects of repeated restraint stress on energy balance and behavior of mice with selective deletion of CRF receptors.	CRHR1 CRHR2	4.06e-06	3	41	2	20392192
Pubmed	Suppression of the MEK/ERK signaling pathway reverses depression-like behaviors of CRF2-deficient mice.	CRHR1 CRHR2	4.06e-06	3	41	2	18843268
Pubmed	The intracellular C-terminus confers compartment-specific targeting of voltage-gated calcium channels.	CACNA1A CACNA1B	4.06e-06	3	41	2	38996073
Pubmed	Mice deficient for both corticotropin-releasing factor receptor 1 (CRFR1) and CRFR2 have an impaired stress response and display sexually dichotomous anxiety-like behavior.	CRHR1 CRHR2	4.06e-06	3	41	2	11756502
Pubmed	Specificity and regulation of extracellularly regulated kinase1/2 phosphorylation through corticotropin-releasing factor (CRF) receptors 1 and 2beta by the CRF/urocortin family of peptides.	CRHR1 CRHR2	4.06e-06	3	41	2	14670995
Pubmed	Inhibition of corticotropin-releasing hormone receptor 1 and activation of receptor 2 protect against colonic injury and promote epithelium repair.	CRHR1 CRHR2	4.06e-06	3	41	2	28492284
Pubmed	Distribution of corticotropin-releasing factor (CRF) receptor binding in the mouse brain using a new, high-affinity radioligand, [125 I]-PD-Sauvagine.	CRHR1 CRHR2	4.06e-06	3	41	2	28842924
Pubmed	Identification of a novel murine receptor for corticotropin-releasing hormone expressed in the heart.	CRHR1 CRHR2	4.06e-06	3	41	2	7565810
Pubmed	Stress-induced differences in primary and secondary resistance against bacterial sepsis corresponds with diverse corticotropin releasing hormone receptor expression by pulmonary CD11c+ MHC II+ and CD11c- MHC II+ APCs.	CRHR1 CRHR2	4.06e-06	3	41	2	18166336
Pubmed	Distinct roles for Cav2.1-2.3 in activity-dependent synaptic dynamics.	CACNA1A CACNA1B	4.06e-06	3	41	2	24523520
Pubmed	Corticotropin-releasing factor, urocortin 1, and their receptors in the mouse spinal cord.	CRHR1 CRHR2	4.06e-06	3	41	2	17444496
Pubmed	Animal models of CRH excess and CRH receptor deficiency display altered adaptations to stress.	CRHR1 CRHR2	4.06e-06	3	41	2	11337086
Pubmed	Plasma Corticotropin-Releasing Factor Receptors and B7-2⁺ Extracellular Vesicles in Blood Correlate with Irritable Bowel Syndrome Disease Severity.	CRHR1 CRHR2	4.06e-06	3	41	2	30704133
Pubmed	Molecular moieties masking Ca2+-dependent facilitation of voltage-gated Cav2.2 Ca2+ channels.	CACNA1A CACNA1B	4.06e-06	3	41	2	29208674
Pubmed	Increased depression-like behaviors in corticotropin-releasing factor receptor-2-deficient mice: sexually dichotomous responses.	CRHR1 CRHR2	4.06e-06	3	41	2	12832554
Pubmed	Molecular Basis of Regulating High Voltage-Activated Calcium Channels by S-Nitrosylation.	CACNA1A CACNA1B	4.06e-06	3	41	2	26507659
Pubmed	Lack of interaction between etifoxine and CRF1 and CRF2 receptors in rodents.	CRHR1 CRHR2	4.06e-06	3	41	2	16769145
Pubmed	Activated CRH receptors inhibit autophagy by repressing conversion of LC3BI to LC3BII.	CRHR1 CRHR2	4.06e-06	3	41	2	30849520
Pubmed	Sex-Dependent Effects of Mild Blast-induced Traumatic Brain Injury on Corticotropin-releasing Factor Receptor Gene Expression: Potential Link to Anxiety-like Behaviors.	CRHR1 CRHR2	4.06e-06	3	41	2	30248435
Pubmed	A single episode of restraint stress regulates central corticotrophin- releasing hormone receptor expression and binding in specific areas of the mouse brain.	CRHR1 CRHR2	4.06e-06	3	41	2	19302188
Pubmed	Synapse and Active Zone Assembly in the Absence of Presynaptic Ca2+ Channels and Ca2+ Entry.	CACNA1A CACNA1B	8.12e-06	4	41	2	32616470
Pubmed	Constitutive and ghrelin-dependent GHSR1a activation impairs CaV2.1 and CaV2.2 currents in hypothalamic neurons.	CACNA1A CACNA1B	8.12e-06	4	41	2	26283199
Pubmed	Corticotropin-releasing factor receptor-dependent effects of repeated stress on tau phosphorylation, solubility, and aggregation.	CRHR1 CRHR2	8.12e-06	4	41	2	22451915
Pubmed	Enhanced pelvic responses to stressors in female CRF-overexpressing mice.	CRHR1 CRHR2	8.12e-06	4	41	2	17194724
Pubmed	Corticotropin-releasing factor-1 receptor involvement in behavioral neuroadaptation to ethanol: a urocortin1-independent mechanism.	CRHR1 CRHR2	8.12e-06	4	41	2	18591672
Pubmed	Corticotropin-releasing hormone, its binding protein and receptors in human cervical tissue at preterm and term labor in comparison to non-pregnant state.	CRHR1 CRHR2	8.12e-06	4	41	2	16734917
Pubmed	Expression patterns of CRH, CRH receptors, and CRH binding protein in human gestational tissue at term.	CRHR1 CRHR2	8.12e-06	4	41	2	12784189
Pubmed	Corticotropin-releasing hormone receptors mediate apoptosis via cytosolic calcium-dependent phospholipase A₂ and migration in prostate cancer cell RM-1.	CRHR1 CRHR2	8.12e-06	4	41	2	24776847
Pubmed	A protein phosphatase 2calpha-Ca2+ channel complex for dephosphorylation of neuronal Ca2+ channels phosphorylated by protein kinase C.	CACNA1A CACNA1B	8.12e-06	4	41	2	15728831
Pubmed	Urocortin II gene is highly expressed in mouse skin and skeletal muscle tissues: localization, basal expression in corticotropin-releasing factor receptor (CRFR) 1- and CRFR2-null mice, and regulation by glucocorticoids.	CRHR1 CRHR2	8.12e-06	4	41	2	14736736
Pubmed	Labelling of CRF1 and CRF2 receptors using the novel radioligand, [3H]-urocortin.	CRHR1 CRHR2	8.12e-06	4	41	2	9423932
Pubmed	The MAP1B-LC1/UBE2L3 complex catalyzes degradation of cell surface CaV2.2 channels.	CACNA1A CACNA1B	8.12e-06	4	41	2	25483588
Pubmed	Deciphering the Contributions of CRH Receptors in the Brain and Pituitary to Stress-Induced Inhibition of the Reproductive Axis.	CRHR1 CRHR2	8.12e-06	4	41	2	30214395
Pubmed	Structural basis for hormone recognition by the Human CRFR2{alpha} G protein-coupled receptor.	CRHR1 CRHR2	8.12e-06	4	41	2	20966082
Pubmed	Cerebellar granule cell signaling is indispensable for normal motor performance.	CACNA1A CACNA1B	8.12e-06	4	41	2	37141091
Pubmed	Interactions of Rabconnectin-3 with Cav2 calcium channels.	CACNA1A CACNA1B	8.12e-06	4	41	2	31253182
Pubmed	Distribution and expression of CRF receptor 1 and 2 mRNAs in the CRF over-expressing mouse brain.	CRHR1 CRHR2	8.12e-06	4	41	2	16423327
Pubmed	Predicting risk of bacterial vaginosis: the role of race, smoking and corticotropin-releasing hormone-related genes.	CRHR1 CRHR2	8.12e-06	4	41	2	19131402
Pubmed	Cloning and characterization of human urocortin.	CRHR1 CRHR2	8.12e-06	4	41	2	8612563
Pubmed	Corticotropin-releasing hormone system in human adipose tissue.	CRHR1 CRHR2	8.12e-06	4	41	2	14764822
Pubmed	Ethanol augments GABAergic transmission in the central amygdala via CRF1 receptors.	CRHR1 CRHR2	8.12e-06	4	41	2	15001778
Pubmed	G protein-gated inhibitory module of N-type (ca(v)2.2) ca2+ channels.	CACNA1A CACNA1B	8.12e-06	4	41	2	15953418
Pubmed	Chromosomal localization of the human genes for alpha 1A, alpha 1B, and alpha 1E voltage-dependent Ca2+ channel subunits.	CACNA1A CACNA1B	1.35e-05	5	41	2	8825650
Pubmed	Dissection of corticotropin-releasing factor system involvement in locomotor sensitivity to methamphetamine.	CRHR1 CRHR2	1.35e-05	5	41	2	20731720
Pubmed	Identification of a cardiac isoform of the murine calcium channel alpha1C (Cav1.2-a) subunit and its preferential binding with the beta2 subunit.	CACNA1A CACNA1B	1.35e-05	5	41	2	16787652
Pubmed	A contextual model for axonal sorting into glomeruli in the mouse olfactory system.	OR10A2 OR10A5	1.35e-05	5	41	2	15186781
Pubmed	Differential regulation of glucose transporters mediated by CRH receptor type 1 and type 2 in human placental trophoblasts.	CRHR1 CRHR2	1.35e-05	5	41	2	22234467
Pubmed	Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice.	CACNA1A CACNA1B	1.35e-05	5	41	2	15451373
Pubmed	Endocannabinoids mediate acute fear adaptation via glutamatergic neurons independently of corticotropin-releasing hormone signaling.	CRHR1 CRHR2	1.35e-05	5	41	2	19077175
Pubmed	Regulation of corticotropin-releasing factor and urocortin 2/3 mRNA by leptin in hypothalamic N39 cells.	CRHR1 CRHR2	1.35e-05	5	41	2	24083959
Pubmed	Functional disorders of the sympathetic nervous system in mice lacking the alpha 1B subunit (Cav 2.2) of N-type calcium channels.	CACNA1A CACNA1B	1.35e-05	5	41	2	11296258
Pubmed	CRF1-R activation of the dynorphin/kappa opioid system in the mouse basolateral amygdala mediates anxiety-like behavior.	CRHR1 CRHR2	1.35e-05	5	41	2	20052275
Pubmed	Matrix metalloproteinases cleave at two distinct sites on human cartilage link protein.	MMP3 HAPLN1	2.03e-05	6	41	2	7694569
Pubmed	An action potential initiation mechanism in distal axons for the control of dopamine release.	CACNA1A CACNA1B	2.03e-05	6	41	2	35324301
Pubmed	Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor.	CRHR1 CRHR2	2.03e-05	6	41	2	11416224
Pubmed	Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis.	CACNA1A CACNA1B	2.03e-05	6	41	2	12827191
Pubmed	Combined effects of exonic polymorphisms in CRHR1 and AVPR1B genes in a case/control study for panic disorder.	CRHR1 CRHR2	2.03e-05	6	41	2	18384079
Pubmed	Association of HPA axis genes with suicidal behaviour in schizophrenia.	CRHR1 CRHR2	2.03e-05	6	41	2	18838498
Cytoband	Ensembl 112 genes in cytogenetic band chr11p15	ANO5 OR10A2 OR52A4P ZDHHC13 OR10A5	1.43e-04	564	41	5	chr11p15
Cytoband	11p15.4	OR10A2 OR52A4P OR10A5	7.68e-04	200	41	3	11p15.4
GeneFamily	Corticotropin releasing hormone receptors	CRHR1 CRHR2	2.48e-06	2	29	2	266
GeneFamily	Calcium voltage-gated channel subunits	CACNA1A CACNA1B	7.88e-04	26	29	2	253
GeneFamily	Olfactory receptors, family 6	OR6S1 OR6J1	3.02e-03	51	29	2	153
GeneFamily	Solute carriers	SLC5A8 SLC25A19 SLC16A2 SLC2A2	3.46e-03	395	29	4	752
GeneFamily	Olfactory receptors, family 10	OR10A2 OR10A5	5.00e-03	66	29	2	157
ToppCell	facs-Trachea-nan-24m-Mesenchymal-chondrocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OMD SLC16A2 TLCD4 HAPLN1	1.91e-05	173	41	4	2226505610af1becc253d0a5550627144ef0ed6b
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNA1B OMD TLCD4 HAPLN1	2.00e-05	175	41	4	f1394aacc8a94ca555dd19aaed5a18da99c6bf40
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNA1B OMD TLCD4 HAPLN1	2.00e-05	175	41	4	7bf1194d93fbe2dbf9d953e0a32b2a6d88251ed1
ToppCell	Thalamus-Neuronal-Excitatory\|Thalamus / BrainAtlas - Mouse McCarroll V32	MAL2 ANO5 TLCD4 CFTR	2.05e-05	176	41	4	d2bbf13d21fb7582d7e5f90cd61a4ebe1cfccd66
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	OMD SLC16A2 TLCD4 HAPLN1	2.05e-05	176	41	4	77c3da2eaa072a6baefb5087fd07ec18c5e271cd
ToppCell	PND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAL2 RNF180 SOAT1 CFTR	2.19e-05	179	41	4	bf012825e88626e59cd1deebf67c2cd269ce4829
ToppCell	droplet-Lung-LUNG-30m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A3 RNF180 AWAT1 SOAT1	2.28e-05	181	41	4	8fcdab61fad2efd324d2b27c58f5a594f1dc15de
ToppCell	facs-Trachea-24m-Epithelial-glandular_epithelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAL2 ANO5 SLC5A8 CFTR	2.44e-05	184	41	4	61caaa31975e05c9a6512079c791fed5a9e2d39f
ToppCell	facs-Trachea-24m-Epithelial-glandular_epithelial-lung_secretory_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAL2 ANO5 SLC5A8 CFTR	2.44e-05	184	41	4	03da0f0f89f1ca5a3ccca1e22972f3129464e68e
ToppCell	facs-Trachea-24m-Epithelial-glandular_epithelial-lung_secretory_cell-mucous\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAL2 ANO5 SLC5A8 CFTR	2.44e-05	184	41	4	9ed2a65a4ca0ebbbb89ace61027522f93369843d
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A3 SLC5A8 CFTR TMEM147	2.76e-05	190	41	4	36e83995021ba16690f84e2077a9e8baec547d05
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A3 SLC5A8 CFTR TMEM147	2.76e-05	190	41	4	d26be9e1b676f750e716b91ebc3598fac3735612
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Gpc3_Slc18a3\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SEMA5B PTH2R CFTR	2.71e-04	137	41	3	d346086f42d8f04d3fa67fe696834284acdc7080
ToppCell	droplet-Liver-hepatocytes-3m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC25A19 SLC2A2 TLCD4	3.33e-04	147	41	3	00619115b9a1ec2b967c2992043b41974ece63c4
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CACNA1A SEMA5B HAPLN1	3.88e-04	155	41	3	77fdae85d36efb776db977eb424b32487ef222e4
ToppCell	P28-Epithelial-epithelial_progenitor_cell-epi_progenitor\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MAL2 SOAT1 CFTR	3.88e-04	155	41	3	be575a0096415705dba425002247289ff8f89474
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1A ANO5 TRPV3	4.18e-04	159	41	3	7747cef94c55144fddcd024a7495318357f1351b
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMP3 ALOX5AP CDS2	4.18e-04	159	41	3	f7803f7b4e0379ae8256ec53110833bedee7db98
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMP3 ALOX5AP CDS2	4.18e-04	159	41	3	6e2d38e78d2ef7803e8bb154b5c788bf62a41045
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1A CACNA1B ANO5	4.58e-04	164	41	3	be49af6335f2505065cde2cb9800e4a5516811b1
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC5A8 SEMA5B CRHR2	4.83e-04	167	41	3	4e613be2b3ba01160b0c0254fce3c4f72220e580
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_MYBPHL\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC5A8 SEMA5B CRHR2	4.83e-04	167	41	3	c7d1e84af1f4d7430858287520ac2cfa36203642
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC5A8 SEMA5B CRHR2	4.83e-04	167	41	3	18ad85751bd892309627eefc357eb28ec5a7c300
ToppCell	P28-Epithelial-epithelial_progenitor_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MAL2 SOAT1 CFTR	4.91e-04	168	41	3	03c95ad3684caec7a6d581006b237cc5fa230685
ToppCell	367C-Epithelial_cells-Epithelial-B_(AT2)\|367C / Donor, Lineage, Cell class and subclass (all cells)	MAL2 SLC5A8 CFTR	4.91e-04	168	41	3	e20e1936573fdde78426d7a4eb45c458d5c4dbb4
ToppCell	367C-Epithelial_cells-Epithelial-B_(AT2)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	MAL2 SLC5A8 CFTR	4.91e-04	168	41	3	16b517e3159ad6e6d25fd48f7d5f46e77b2b318d
ToppCell	P28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CACNA1A MAL2 OMD	4.91e-04	168	41	3	8c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC5A8 SEMA5B CRHR2	5.00e-04	169	41	3	bddb28a8b9afbe4a68f082e82caf96a6666fc674
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC5A8 SEMA5B CRHR2	5.00e-04	169	41	3	5ce46bac8e767feec7ecdc61689de225c49bd3f7
ToppCell	P07-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MAL2 SOAT1 CFTR	5.00e-04	169	41	3	53e863de064d44e1d36e21fb3dbba37ae020f6e9
ToppCell	P07-Epithelial-epithelial_progenitor_cell-epi_progenitor\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MAL2 SOAT1 CFTR	5.00e-04	169	41	3	1a47a4892a5e6a69555f5332308503526e5422a7
ToppCell	P07-Epithelial-epithelial_progenitor_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MAL2 SOAT1 CFTR	5.00e-04	169	41	3	ec23caecbb0d969307e33e9df8499ddcd1420305
ToppCell	facs-Trachea-3m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l12\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KCNK13 RNF180 ALOX5AP	5.08e-04	170	41	3	f524b73d65941ebef7671c46df4362a3f15d24fc
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CACNA1B PTH2R CFTR	5.08e-04	170	41	3	fefb07a7e308b620f946b9ff2b01e1796446fe38
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231\|Adult / Lineage, Cell type, age group and donor	MAL2 AWAT1 CFTR	5.08e-04	170	41	3	269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC5A8 SEMA5B CRHR2	5.08e-04	170	41	3	ce2fd2fbbfd152290be0cf8e513f102fdc182b41
ToppCell	P28-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MAL2 SOAT1 CFTR	5.08e-04	170	41	3	d0ed3a8a7ad96c05641ec409b0a69c4fb094893c
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAL2 SLC5A8 ZDHHC13	5.08e-04	170	41	3	833b4f44ea1fa673dfc6b43ce45a79fe68ae3b05
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC5A8 SEMA5B CRHR2	5.08e-04	170	41	3	ab5c6a91c371e4df15b0842828dc55039695ab06
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A CACNA1B SLC5A8	5.08e-04	170	41	3	6a98f47f8c2b5b15e09169bd82eff1e6bf76e5a6
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_MYBPHL\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC5A8 SEMA5B CRHR2	5.08e-04	170	41	3	4aa9e597f6550ac8cac3137a98be58e71efd07d6
ToppCell	LPS-IL1RA-Epithelial_alveolar-Mes-like\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1B MAL2 CFTR	5.17e-04	171	41	3	3ad4f138d9570500cfb4423a2be16bb7d1cacbf8
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A CRHR1 PTH2R	5.17e-04	171	41	3	99176a932569fa1c7e1c01009684f5a65244b96e
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_MYBPHL\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC5A8 SEMA5B CRHR2	5.17e-04	171	41	3	0417fa805ca0acb7e9f6a30bc7b6bdbaba77844d
ToppCell	LPS-IL1RA-Epithelial_alveolar-Mes-like-AT2_Progenitor\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1B MAL2 CFTR	5.17e-04	171	41	3	ca2775a17b5c339c480a963953b6fa2b0731f24d
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANO5 ZDHHC13 SCAMP1	5.26e-04	172	41	3	5401ac7739f95fb8681cfb4747ab6e447a3c2ae8
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANO5 ZDHHC13 SCAMP1	5.26e-04	172	41	3	b3da7f488d191214d7bb74fbac189fe8c29ee6cd
ToppCell	droplet-Fat-Scat-18m\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMP3 ALOX5AP SOAT1	5.26e-04	172	41	3	8a4a5ad65eec92ce4fa45c5aa01c28666307455b
ToppCell	367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	MAL2 TLCD4 CFTR	5.26e-04	172	41	3	a9e65201ad9ab4f64251aba2c0bb3d8f9e0193b6
ToppCell	367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|367C / Donor, Lineage, Cell class and subclass (all cells)	MAL2 TLCD4 CFTR	5.26e-04	172	41	3	26006967d0c82f7bd9b36a18e97a1b93e856aa67
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANO5 ZDHHC13 SCAMP1	5.26e-04	172	41	3	74dd4a7acb2cf857fed20219e4d7dc1adfbaa398
ToppCell	P07-Epithelial\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MAL2 SOAT1 CFTR	5.35e-04	173	41	3	8b10087a917b825809d35a2b2b349c73a2782472
ToppCell	P03-Epithelial-epithelial_progenitor_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MAL2 SOAT1 CFTR	5.44e-04	174	41	3	23c7fdfc73170cfc5cdee5bb7fbee0c8bbbbca07
ToppCell	droplet-Tongue-Unstain-18m-Myeloid\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNK13 RNF180 ALOX5AP	5.44e-04	174	41	3	f2eb0199f59e1e2f46da344c05289876bd254fa3
ToppCell	droplet-Tongue-Unstain-18m-Myeloid-Langerhans_cell\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNK13 RNF180 ALOX5AP	5.44e-04	174	41	3	9019011eb8d9b7a95804fc11434f0fd42418103a
ToppCell	droplet-Tongue-Unstain-18m-Myeloid-Langerhans_cell\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNK13 RNF180 ALOX5AP	5.44e-04	174	41	3	deafbd0c2523afe09cc42f8c7b33945f3f5c00b4
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Adult / Lineage, Cell type, age group and donor	CACNA1A CACNA1B ANO5	5.53e-04	175	41	3	4db1a3c284488b3f6de7568363f176d74e2a4587
ToppCell	P28-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TLCD4 SOAT1 CFTR	5.53e-04	175	41	3	8a4ed775ff973123dbcfe9c809959d11a62450c9
ToppCell	P03-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MAL2 SOAT1 CFTR	5.53e-04	175	41	3	a6d9ca35d3c4b4e3889d0a69b514f63ae630da6b
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231\|Adult / Lineage, Cell type, age group and donor	CACNA1A CACNA1B ANO5	5.53e-04	175	41	3	8d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCell	PND01-03-samps-Epithelial-Alveolar_epithelial-AT2\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	MAL2 SOAT1 CFTR	5.62e-04	176	41	3	ac76f2cd6c63f30b38b89b58bad2baa4dde8ce3a
ToppCell	droplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ATP13A3 ALOX5AP SOAT1	5.62e-04	176	41	3	e74ad0db3b05897edcfabeb11008ede2b9eeb638
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANO5 SLC25A19 SCAMP1	5.62e-04	176	41	3	76fdf211bce101e83a27d822cb399487bd107027
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP13A3 AWAT1 SOAT1	5.72e-04	177	41	3	67cc3a6461db5e0678f96b18224aeb83ad34b0f4
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_LINC00507_CTXN3\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAL2 SLC5A8 CRHR2	5.72e-04	177	41	3	96d639407f79669f3990138793d157b94273581c
ToppCell	droplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ATP13A3 ALOX5AP SOAT1	5.72e-04	177	41	3	71919b5c9bfa87fdd2cd44dfa057b66ea081be5d
ToppCell	droplet-Lung-LUNG-30m-Epithelial-Club_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAL2 SLC2A2 CFTR	5.72e-04	177	41	3	092a345cb802f183322aa5542341ba2d96d4f06a
ToppCell	droplet-Lung-LUNG-30m-Epithelial-club_cell_of_bronchiole\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAL2 SLC2A2 CFTR	5.72e-04	177	41	3	7ac99ff16df94b4e08d361e3d98a7b3af8d6ee3b
ToppCell	COVID-19-kidney-PCT-S1/S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC5A8 SLC2A2 PTH2R	5.81e-04	178	41	3	23a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A ALOX5AP CRHR1	6.00e-04	180	41	3	6ac62bf1251978c8c12e715f7b73144fca619794
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNF180 SEMA5B AWAT1	6.10e-04	181	41	3	1037051eb82313c13346617b33f3c4c648181c4d
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRPV3 MMP3 OMD	6.10e-04	181	41	3	6730e249cac55ae892cc567d9211615882f3dab4
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRPV3 MMP3 OMD	6.10e-04	181	41	3	3462aa1c08fbaf613b6278ab2c7a5a0940bf537d
ToppCell	COVID-19-kidney-Stressed_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC5A8 SLC2A2 PTH2R	6.10e-04	181	41	3	6980ea624151da32b7f537f263e40fcb87a02e81
ToppCell	droplet-Heart-4Chambers-21m-Neuronal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAL2 SLC5A8 TLCD4	6.10e-04	181	41	3	3fd16229a63de0971db5d48860c01173d7db518f
ToppCell	Epithelial-lung_neuroendocrine_cell_(PNEC)\|World / Lineage, Cell type, age group and donor	CACNA1A CACNA1B ANO5	6.20e-04	182	41	3	57bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC5A8 SLC16A2 SLC2A2	6.20e-04	182	41	3	be8dd52898525ce6632af0adc2801944f3ac10bd
ToppCell	facs-Heart-RA\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC16A2 ALOX5AP SOAT1	6.20e-04	182	41	3	8292e8e8474c930ffb88cbab4f6ebdb6f58db645
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC5A8 SLC16A2 SLC2A2	6.20e-04	182	41	3	faf0dfa3adc2d2706b6942b5127093ccdc856447
ToppCell	COPD-Epithelial-ATII\|World / Disease state, Lineage and Cell class	MAL2 SLC5A8 CFTR	6.30e-04	183	41	3	8e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCell	COVID-19-kidney-PCT-S1/S2\|kidney / Disease (COVID-19 only), tissue and cell type	SLC5A8 SLC2A2 PTH2R	6.40e-04	184	41	3	dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCell	PND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAL2 SOAT1 CFTR	6.40e-04	184	41	3	49705c8fec565b16216bdf48e83e27521f52d99a
ToppCell	droplet-Lung-nan-21m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAL2 TLCD4 CFTR	6.50e-04	185	41	3	0e7351cd6d6e6e8c29573042e168da50ee496cfc
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Adult / Lineage, Cell type, age group and donor	MAL2 CFTR CSTPP1	6.50e-04	185	41	3	673f0c688ae6984bc8027df2da335787924f4137
ToppCell	droplet-Lung-nan-21m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAL2 TLCD4 CFTR	6.50e-04	185	41	3	6938ac3cab536cf8a474eba441ce6dcdfcc43b53
ToppCell	COVID-19-kidney-Mito-rich_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC5A8 SLC2A2 PTH2R	6.50e-04	185	41	3	1bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCell	PND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAL2 SOAT1 CFTR	6.50e-04	185	41	3	2adb32096aa3473f8d417e5ce9e65264beca9b52
ToppCell	droplet-Fat-Scat-21m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAL2 SLC5A8 TLCD4	6.60e-04	186	41	3	de88fafac51049ec1920695844d8ce8057940272
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA5B CRHR2 CDS2	6.60e-04	186	41	3	6568358812f0ca4e0161a1a1b29682fbced35c79
ToppCell	21-Trachea-Epithelial-Goblet-like_secretory\|Trachea / Age, Tissue, Lineage and Cell class	MAL2 MMP3 CFTR	6.60e-04	186	41	3	f8cddad28896f0edf10a8645fa49a011b22b120d
ToppCell	droplet-Fat-Scat-21m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAL2 SLC5A8 TLCD4	6.60e-04	186	41	3	59710cff3f6f7c318ee2524b44c1a909f312c25e
ToppCell	facs-Lung-18m-Epithelial-alveolar_epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAL2 TLCD4 CFTR	6.60e-04	186	41	3	c7214e762b3b48197fdd0b36a50a4de2550a888f
ToppCell	droplet-Fat-Scat-21m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAL2 SLC5A8 TLCD4	6.60e-04	186	41	3	7ff73ab8fed5da779ee9c7bd2e14a8363edb7509
ToppCell	Control-Epithelial-ATII\|World / Disease state, Lineage and Cell class	MAL2 SLC5A8 CFTR	6.60e-04	186	41	3	f4b6e401e19a71beddc73d8a1e08359f7c4025cf
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1A CACNA1B ANO5	6.60e-04	186	41	3	b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A CRHR1 PTH2R	6.71e-04	187	41	3	1b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCell	PND03\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAL2 ALOX5AP SOAT1	6.71e-04	187	41	3	b3fcb36d853adfdea7172c5591de06f027e50af3
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC5A8 SLC16A2 CFTR	6.81e-04	188	41	3	842982de2197770f999a70083ed9fca40ac22d79
ToppCell	facs-Lung-EPCAM-3m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAL2 TLCD4 CFTR	6.81e-04	188	41	3	3dd571bd8e7358b4346dea71f6bf9602dabf583c
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC5A8 SLC16A2 CFTR	6.81e-04	188	41	3	a0815eaf68eedd6e5ec4af520df80a6ab4eb0864
Drug	phenylalanyl corticotropin-releasing factor (12-41)	CRHR1 CRHR2	3.16e-06	2	41	2	ctd:C113202
Drug	PNU-107859	MMP3 SCAMP1 CRHR1 SLC2A2 CRHR2	1.48e-05	174	41	5	CID004369084
Drug	AC 110	CACNA1A CACNA1B	1.89e-05	4	41	2	CID000022860
Drug	Crf3	CRHR1 CRHR2	1.89e-05	4	41	2	CID000522687
Drug	S 8510	CACNA1A CACNA1B	3.15e-05	5	41	2	CID005488383
Drug	1-EBIO	CACNA1A CACNA1B CFTR	4.04e-05	37	41	3	CID000082320
Drug	Phloretin	SLC16A2 SLC2A2 CFTR	4.04e-05	37	41	3	ctd:D010693
Drug	8-cyclopentyltheophylline	CACNA1A CACNA1B CFTR	4.38e-05	38	41	3	CID000001917
Drug	3,4-dihydroquinazoline	CACNA1A CACNA1B	4.72e-05	6	41	2	CID000583065
Drug	methyl nitrate	CRHR1 CRHR2	4.72e-05	6	41	2	CID000011724
Drug	alpha-sialylcholesterol	CACNA1A CACNA1B	4.72e-05	6	41	2	CID000133976
Drug	deazapurine	CRHR1 CRHR2	6.61e-05	7	41	2	CID000261591
Drug	3-cyclohexylpropionate	CRHR1 CRHR2	6.61e-05	7	41	2	CID000069702
Drug	APMPA	CACNA1A CACNA1B	6.61e-05	7	41	2	CID000512300
Drug	astressin	CRHR1 CRHR2	6.61e-05	7	41	2	ctd:C104416
Drug	Crf6	CRHR1 CRHR2	8.80e-05	8	41	2	CID005460740
Drug	astressin B	CRHR1 CRHR2	1.13e-04	9	41	2	ctd:C120841
Drug	SR 48968	CACNA1B TRPV3 CRHR1	1.56e-04	58	41	3	CID000104974
Drug	4-aminopiperidine	CACNA1A CACNA1B	1.72e-04	11	41	2	CID000424361
Drug	leys	CACNA1A CACNA1B	1.72e-04	11	41	2	CID000484683
Drug	IAA-94	CACNA1A CACNA1B CFTR	1.81e-04	61	41	3	CID000003667
Drug	AC1NUNCT	CRHR1 CRHR2	2.06e-04	12	41	2	CID000093213
Drug	AC1L2VU3	CACNA1A CACNA1B	2.06e-04	12	41	2	CID000129572
Drug	mibefradil	CACNA1A CACNA1B KCNK13	2.09e-04	64	41	3	CID000060662
Drug	palmatine	CACNA1B SLC5A8	2.44e-04	13	41	2	CID000019009
Drug	AC1MIXC3	CRHR1 CRHR2	2.44e-04	13	41	2	CID003081671
Drug	AC1L2AC7	CACNA1A CACNA1B SOAT1	2.61e-04	69	41	3	CID000068733
Drug	AC1L1JG6	CACNA1A CACNA1B	2.84e-04	14	41	2	CID000005026
Drug	1,3-dipropylxanthine	CACNA1A CACNA1B CFTR	3.21e-04	74	41	3	CID000169317
Drug	butamben	CACNA1A CACNA1B	3.27e-04	15	41	2	CID000002482
Drug	P-44	CRHR1 CRHR2	3.27e-04	15	41	2	CID000200876
Drug	Fedotozina	CRHR1 CRHR2	3.27e-04	15	41	2	CID000060764
Drug	Nitric Oxide	CACNA1A CACNA1B MMP3 CRHR1 CFTR	3.29e-04	336	41	5	ctd:D009569
Drug	pentasulfane	CACNA1A CACNA1B	3.74e-04	16	41	2	CID000448216
Drug	NBI-27914	CRHR1 CRHR2	3.74e-04	16	41	2	CID000176157
Drug	Amino nucleoside	MMP3 SOAT1	3.74e-04	16	41	2	CID003000338
Drug	Verapamil	CACNA1A CACNA1B	3.74e-04	16	41	2	DB00661
Drug	DeltaR	CACNA1B CFTR	4.23e-04	17	41	2	CID000028718
Drug	Phenformin hydrochloride [834-28-6]; Up 200; 16.6uM; HL60; HT_HG-U133A	ENTPD7 CACNA1A MMP3 PTH2R	4.29e-04	197	41	4	2350_UP
Drug	Prilocaine hydrochloride [1786-81-8]; Up 200; 15.6uM; PC3; HT_HG-U133A	ENTPD7 MMP3 OMD CRHR2	4.29e-04	197	41	4	3727_UP
Drug	Haloperidol [52-86-8]; Up 200; 10.6uM; HL60; HG-U133A	ATP13A3 CRHR2 SOAT1 CDS2	4.45e-04	199	41	4	2039_UP
Drug	capsazepine	CACNA1A CACNA1B TRPV3	4.67e-04	84	41	3	CID002733484
Drug	MR 2034	CRHR1 CRHR2	4.75e-04	18	41	2	CID000123980
Drug	C13932	CACNA1A CACNA1B TRPV3 KCNK13	5.07e-04	206	41	4	CID000168297
Drug	N6-Me-dAdo	CACNA1A CACNA1B	5.31e-04	19	41	2	CID000168948
Drug	pranidipine	CACNA1A CACNA1B	5.31e-04	19	41	2	CID006436048
Drug	NIH-3	CRHR1 CRHR2	5.31e-04	19	41	2	CID009822007
Drug	5-iodotubercidin	MMP3 SLC2A2	5.31e-04	19	41	2	ctd:C034214
Drug	R1C	CRHR1 CRHR2	5.89e-04	20	41	2	CID009961424
Drug	AC1MBZ1C	CACNA1A CACNA1B CRHR1 PTH2R CFTR	6.26e-04	387	41	5	CID000003541
Drug	anilinonaphthalene	CRHR1 CRHR2	6.50e-04	21	41	2	CID000008679
Drug	CGP 52432	CRHR1 CRHR2	6.50e-04	21	41	2	CID000132252
Drug	CID9572793	CRHR1 CRHR2	7.14e-04	22	41	2	CID009572793
Drug	N-arachidonoylethanolamine	CACNA1A CACNA1B TRPV3 KCNK13	7.18e-04	226	41	4	CID000002185
Drug	deoxypyridinoline	MMP3 PTH2R HAPLN1	7.32e-04	98	41	3	CID000105071
Drug	LY320135	CACNA1A CACNA1B	7.81e-04	23	41	2	CID005311257
Drug	Ncz	SLC25A19 ALOX5AP	7.81e-04	23	41	2	CID000446415
Drug	NSC717817	MMP3 SLC16A2	7.81e-04	23	41	2	CID005287845
Drug	alpha-conotoxin SI	CACNA1A CACNA1B	7.81e-04	23	41	2	CID000163979
Drug	droperidol	CACNA1B CFTR	7.81e-04	23	41	2	CID000003168
Drug	AC1L1D9R	CACNA1A CACNA1B CFTR	8.46e-04	103	41	3	CID000002254
Drug	pD 8	CRHR1 CRHR2	8.52e-04	24	41	2	CID000656948
Drug	PCMBS	SLC16A2 SLC2A2 CFTR	8.94e-04	105	41	3	CID000011136
Drug	levodopa/carbidopa	CACNA1A OMD	1.00e-03	26	41	2	CID000104778
Drug	Shu 9119	CRHR1 CRHR2	1.00e-03	26	41	2	CID006440621
Drug	mAHP	CACNA1A CACNA1B	1.08e-03	27	41	2	CID000220531
Drug	Immucillin-G	SLC16A2 SOAT1	1.08e-03	27	41	2	CID000001334
Drug	eniluracil	CACNA1A CACNA1B	1.08e-03	27	41	2	CID000043157
Drug	sodium silicate	CRHR1 CRHR2	1.16e-03	28	41	2	CID000023266
Drug	Virginiamycin S1	CACNA1B TRPV3	1.16e-03	28	41	2	CID000122731
Drug	AC1NBU2S	CACNA1A CACNA1B ALOX5AP	1.22e-03	117	41	3	CID004473765
Drug	homophenylalanine	MMP3 CFTR	1.33e-03	30	41	2	CID000102530
Drug	InsS6	CACNA1A SLC5A8	1.33e-03	30	41	2	CID000065302
Drug	amlodipine	CACNA1A CACNA1B SLC16A2	1.51e-03	126	41	3	CID000002162
Drug	CNQX	CACNA1A CACNA1B HAPLN1	1.51e-03	126	41	3	CID000002821
Drug	3-aminopropylphosphinic acid	CACNA1A CACNA1B	1.52e-03	32	41	2	CID006335948
Drug	polyethylenimine	MMP3 SCAMP1 CFTR	1.58e-03	128	41	3	CID000009033
Drug	A61603	CACNA1A CACNA1B	1.61e-03	33	41	2	CID004038180
Drug	CNS 1145	CACNA1A CACNA1B	1.61e-03	33	41	2	CID000190902
Drug	IHC-64	CACNA1A CACNA1B	1.61e-03	33	41	2	CID000162753
Drug	6,7-dinitroquinoxaline	CRHR1 CRHR2	1.61e-03	33	41	2	CID002724608
Drug	Aliquat 336	CACNA1A CACNA1B	1.71e-03	34	41	2	CID000021218
Drug	fluspirilene	CACNA1A CACNA1B	1.71e-03	34	41	2	CID000003396
Drug	Barium permanganate	CACNA1A CACNA1B KCNK13	1.77e-03	133	41	3	CID000024587
Disease	functional colonic disease (biomarker_via_orthology)	CRHR1 CRHR2	5.37e-06	3	40	2	DOID:3877 (biomarker_via_orthology)
Disease	familial hemiplegic migraine 1 (implicated_via_orthology)	CACNA1A CACNA1B	5.37e-06	3	40	2	DOID:0111181 (implicated_via_orthology)
Disease	migraine (implicated_via_orthology)	CACNA1A CACNA1B	1.07e-05	4	40	2	DOID:6364 (implicated_via_orthology)
Disease	migraine with aura (is_implicated_in)	CACNA1A TRPV3	2.68e-05	6	40	2	DOID:10024 (is_implicated_in)
Disease	hereditary ataxia (implicated_via_orthology)	CACNA1A CACNA1B	3.75e-05	7	40	2	DOID:0050951 (implicated_via_orthology)
Disease	irritable bowel syndrome (biomarker_via_orthology)	CRHR1 CRHR2	4.99e-05	8	40	2	DOID:9778 (biomarker_via_orthology)
Disease	asthma (is_implicated_in)	ALOX5AP CRHR1 CRHR2 CFTR	6.07e-05	157	40	4	DOID:2841 (is_implicated_in)
Disease	Anorexia	CRHR1 CRHR2	2.70e-04	18	40	2	C0003123
Disease	glomerulonephritis (biomarker_via_orthology)	MMP3 ALOX5AP	3.35e-04	20	40	2	DOID:2921 (biomarker_via_orthology)
Disease	Coronary heart disease	MMP3 MACO1	4.85e-04	24	40	2	C0010068
Disease	Anhedonia	CRHR1 CRHR2	4.85e-04	24	40	2	C0178417
Disease	Dwarfism	SLC2A2 HAPLN1	5.27e-04	25	40	2	C0013336
Disease	Parkinson's disease (implicated_via_orthology)	ATP13A3 RRN3P1 RRN3	1.26e-03	157	40	3	DOID:14330 (implicated_via_orthology)
Disease	Anxiety Disorders	CRHR1 CRHR2	1.64e-03	44	40	2	C0003469
Disease	Anxiety neurosis (finding)	CRHR1 CRHR2	1.64e-03	44	40	2	C1279420

Protein segments in the cluster

Peptide	Gene	Start	Entry
FNYYLIFFFGSDFEN	ALOX5AP	131	P20292
TFFAFCYPFSYSDCQ	AGBL5	151	Q8NDL9
CGNEFAYFYFVSFIF	CACNA1A	1781	O00555
FLFQFVNFYSSCFYV	ANO5	561	Q75V66
VNFYSSCFYVAFFKG	ANO5	566	Q75V66
YVRYFNSSAFFFSGF	CFTR	301	P13569
CYKNYFFVFSVIFLY	ATP13A3	1101	Q9H7F0
YFVQNTDFDFFSYAG	GUSBP11	226	Q6P575
VNYFFYGETVTDYFF	CDS2	136	O95674
SDFAYFYFVSFIFLC	CACNA1B	1681	Q00975
NCFGDYHVAFYFAGV	SLC16A2	471	P36021
YYGCALQFYFFCTFA	OR5I1	96	Q13606
NNSEFYGFSEFFYCT	ENTPD7	411	Q9NQZ7
FEEFGFFYFFTGSSQ	MMP3	441	P08254
YDSFRYQGLAFSVFF	MACO1	66	Q8N5G2
YVFFQFYLLAFFFIF	OR52A4P	251	A6NMU1
YIADFCGPYVFFLFA	SLC2A2	456	P11168
FLQSFQGFFVSVFYC	CRHR2	346	Q13324
QGFFVSVFYCFFNGE	CRHR2	351	Q13324
GWSYFDSLYFCFVAF	KCNK13	221	Q9HB14
TQMYFFFFFGVAECF	OR10A2	86	Q9H208
FAACITQFYFYFFLG	OR6S1	96	Q8NH40
TQFYFYFFLGASEFL	OR6S1	101	Q8NH40
FSDFLFAFQIQFYYS	CSTPP1	136	Q9H6J7
RIFGFYCCVFYGQSF	AWAT1	246	Q58HT5
ESFQGFFVSVFYCFL	CRHR1	381	P34998
LDFAYHFTVFVFYFG	MAL2	101	Q969L2
QMYFFFFFGVAECFL	OR10A5	101	Q9H207
VIGFIVFCFLCYFFF	RNF180	576	Q86T96
FCFTSNFNGRFYYLI	HAPLN1	251	P10915
FFFFGVKVHCQYETY	OMD	11	Q99983
FYSACQAVFYTFVFR	RRN3	456	Q9NYV6
KFAQVFGCFFYVYYI	SOAT1	326	P35610
FGCFFYVYYIFERLC	SOAT1	331	P35610
FGAIFSIFAFTYFFV	SLC5A8	81	Q8N695
FRFFVFFFVYICQFA	SCAMP1	216	O15126
ISFAGCITQCYFYFF	OR6J1	91	Q8NGC5
FYFSFIFSIVAFLYF	ZDHHC13	376	Q8IUH4
FYSACQAVFYTFVFR	RRN3P1	81	Q2M238
FFTFQLLFYFVSYWF	TLCD4	16	Q96MV1
NFVAAYDIGLFAYFF	SEMA5B	286	Q9P283
FNSFQGFFVSIIYCY	PTH2R	401	P49190
FFLSFCFYFFYNITL	TRPV3	441	Q8NET8
FGNCFALAYFPYFIT	TMEM147	6	Q9BVK8
TGFMFFSYEFFCNVF	SLC25A19	296	Q9HC21