| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | cysteine-type deubiquitinase activity | 2.58e-04 | 114 | 22 | 3 | GO:0004843 | |
| GeneOntologyMolecularFunction | deubiquitinase activity | 3.30e-04 | 124 | 22 | 3 | GO:0101005 | |
| GeneOntologyMolecularFunction | RNA nuclease activity | 4.33e-04 | 136 | 22 | 3 | GO:0004540 | |
| GeneOntologyMolecularFunction | ubiquitin-like protein peptidase activity | 4.42e-04 | 137 | 22 | 3 | GO:0019783 | |
| GeneOntologyMolecularFunction | catalytic activity, acting on a nucleic acid | 5.77e-04 | 645 | 22 | 5 | GO:0140640 | |
| GeneOntologyMolecularFunction | 3'-5'-RNA exonuclease activity | 7.54e-04 | 37 | 22 | 2 | GO:0000175 | |
| GeneOntologyMolecularFunction | RNA exonuclease activity, producing 5'-phosphomonoesters | 8.81e-04 | 40 | 22 | 2 | GO:0016896 | |
| GeneOntologyMolecularFunction | catalytic activity, acting on RNA | 1.02e-03 | 417 | 22 | 4 | GO:0140098 | |
| GeneOntologyMolecularFunction | RNA exonuclease activity | 1.11e-03 | 45 | 22 | 2 | GO:0004532 | |
| GeneOntologyMolecularFunction | cysteine-type peptidase activity | 1.18e-03 | 192 | 22 | 3 | GO:0008234 | |
| GeneOntologyMolecularFunction | nuclease activity | 2.00e-03 | 231 | 22 | 3 | GO:0004518 | |
| GeneOntologyMolecularFunction | 3'-5' exonuclease activity | 2.04e-03 | 61 | 22 | 2 | GO:0008408 | |
| GeneOntologyMolecularFunction | exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 2.11e-03 | 62 | 22 | 2 | GO:0016796 | |
| GeneOntologyMolecularFunction | cysteine-type endopeptidase activity | 4.00e-03 | 86 | 22 | 2 | GO:0004197 | |
| GeneOntologyMolecularFunction | exonuclease activity | 4.57e-03 | 92 | 22 | 2 | GO:0004527 | |
| GeneOntologyMolecularFunction | monosaccharide binding | 4.86e-03 | 95 | 22 | 2 | GO:0048029 | |
| GeneOntologyMolecularFunction | peptidase activity | 5.21e-03 | 654 | 22 | 4 | GO:0008233 | |
| MousePheno | decreased susceptibility to parasitic infection induced morbidity/mortality | 8.33e-05 | 15 | 13 | 2 | MP:0010751 | |
| Domain | Ub_USP-typ | 7.94e-06 | 4 | 22 | 2 | IPR028135 | |
| Domain | Ubiquitin_3 | 7.94e-06 | 4 | 22 | 2 | PF14836 | |
| Domain | DUSP | 1.98e-05 | 6 | 22 | 2 | SM00695 | |
| Domain | DUSP | 1.98e-05 | 6 | 22 | 2 | PF06337 | |
| Domain | - | 2.77e-05 | 7 | 22 | 2 | 3.30.2230.10 | |
| Domain | Pept_C19_DUSP | 2.77e-05 | 7 | 22 | 2 | IPR006615 | |
| Domain | DUSP | 2.77e-05 | 7 | 22 | 2 | PS51283 | |
| Domain | USP_CS | 6.19e-05 | 66 | 22 | 3 | IPR018200 | |
| Domain | USP_1 | 7.38e-05 | 70 | 22 | 3 | PS00972 | |
| Domain | UCH | 7.70e-05 | 71 | 22 | 3 | PF00443 | |
| Domain | USP_2 | 7.70e-05 | 71 | 22 | 3 | PS00973 | |
| Domain | USP_3 | 8.03e-05 | 72 | 22 | 3 | PS50235 | |
| Domain | USP_dom | 8.03e-05 | 72 | 22 | 3 | IPR028889 | |
| Domain | Peptidase_C19_UCH | 8.03e-05 | 72 | 22 | 3 | IPR001394 | |
| Pubmed | Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes. | 7.12e-07 | 28 | 22 | 3 | 22118674 | |
| Pubmed | Structural variability of the ubiquitin specific protease DUSP-UBL double domains. | 1.15e-06 | 3 | 22 | 2 | 22001210 | |
| Pubmed | Phosphorylation of USP15 and USP4 Regulates Localization and Spliceosomal Deubiquitination. | 1.15e-06 | 3 | 22 | 2 | 31330151 | |
| Pubmed | Evolution of the highly networked deubiquitinating enzymes USP4, USP15, and USP11. | 1.15e-06 | 3 | 22 | 2 | 26503449 | |
| Pubmed | 2.11e-06 | 147 | 22 | 4 | 29576527 | ||
| Pubmed | Structural basis for recruiting and shuttling of the spliceosomal deubiquitinase USP4 by SART3. | 2.29e-06 | 4 | 22 | 2 | 27060135 | |
| Pubmed | 5.72e-06 | 6 | 22 | 2 | 28088760 | ||
| Pubmed | Reciprocal interaction between SIRT6 and APC/C regulates genomic stability. | 6.99e-06 | 440 | 22 | 5 | 34244565 | |
| Pubmed | USP4 is regulated by AKT phosphorylation and directly deubiquitylates TGF-β type I receptor. | 1.07e-05 | 8 | 22 | 2 | 22706160 | |
| Pubmed | USP4 Auto-Deubiquitylation Promotes Homologous Recombination. | 1.07e-05 | 8 | 22 | 2 | 26455393 | |
| Pubmed | 1.82e-05 | 81 | 22 | 3 | 12838346 | ||
| Pubmed | HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways. | 2.45e-05 | 571 | 22 | 5 | 37167062 | |
| Pubmed | Deubiquitinating enzymes: a new class of biological regulators. | 3.99e-05 | 15 | 22 | 2 | 9827704 | |
| Pubmed | 5.16e-05 | 17 | 22 | 2 | 29299163 | ||
| Pubmed | 7.52e-05 | 723 | 22 | 5 | 34133714 | ||
| Pubmed | Usp12 stabilizes the T-cell receptor complex at the cell surface during signaling. | 8.76e-05 | 22 | 22 | 2 | 26811477 | |
| Pubmed | 1.05e-04 | 24 | 22 | 2 | 34983926 | ||
| Pubmed | Genome-wide association study of lung function decline in adults with and without asthma. | 1.87e-04 | 32 | 22 | 2 | 22424883 | |
| Pubmed | Ubiquitin-specific peptidase 2a (USP2a) deubiquitinates and stabilizes β-catenin. | 1.99e-04 | 33 | 22 | 2 | 30323974 | |
| Pubmed | 2.17e-04 | 481 | 22 | 4 | 28190767 | ||
| Pubmed | 2.24e-04 | 35 | 22 | 2 | 33378683 | ||
| Pubmed | 2.38e-04 | 36 | 22 | 2 | 22626734 | ||
| Pubmed | 3.23e-04 | 534 | 22 | 4 | 35032548 | ||
| Pubmed | USP45 and Spindly are part of the same complex implicated in cell migration. | 4.27e-04 | 235 | 22 | 3 | 30258100 | |
| GeneFamily | Ubiquitin specific peptidases | 2.22e-05 | 56 | 18 | 3 | 366 | |
| Coexpression | RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP | 2.17e-05 | 721 | 22 | 6 | M10237 | |
| ToppCell | 3'-Adult-LargeIntestine-Hematopoietic-Myeloid-Macrophages|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 1.06e-04 | 189 | 22 | 3 | b491204cf38dc80a2583e3082a82dda8d77b3fc4 | |
| ToppCell | severe-Myeloid-Immature_Neutrophils_1|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs | 1.16e-04 | 195 | 22 | 3 | becad890a420267ca41e98e61a8da343b51e1945 | |
| ToppCell | severe-Myeloid-Immature_Neutrophils_1|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs | 1.20e-04 | 197 | 22 | 3 | 9599319dd1f80c81356a8624131566cc76d77d7e | |
| ToppCell | NS-critical-LOC-Myeloid-Macrophage|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined) | 1.20e-04 | 197 | 22 | 3 | 5fb0696376a5501b7c87e0f2f5e4fff3da2903f2 | |
| ToppCell | TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9 | 1.22e-04 | 198 | 22 | 3 | 62cbf4b29e8af4983fb47a17f96da62682a5137e | |
| ToppCell | TCGA-Skin-Metastatic-Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9 | 1.22e-04 | 198 | 22 | 3 | af4fb9eb2295c7b90624b38ba25619aa15254efa | |
| ToppCell | TCGA-Skin-Metastatic|TCGA-Skin / Sample_Type by Project: Shred V9 | 1.22e-04 | 198 | 22 | 3 | ad39cce004867f083f8da1954e0cf5a263815184 | |
| ToppCell | BAL-Mild-Myeloid-TRAM-TRAM3|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09) | 1.23e-04 | 199 | 22 | 3 | bae7aa25f9e23fea19371390b8306e9dc3e4d549 | |
| ToppCell | BAL-Mild-Myeloid-TRAM-TRAM3|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 1.23e-04 | 199 | 22 | 3 | 4e518651ff219e163cfd9deb58566df6308aa3f7 | |
| ToppCell | Mild_COVID-19-Myeloid-TRAM3|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30） | 1.23e-04 | 199 | 22 | 3 | 4ab5da8ab757e8294c743949a5374b6e6a388913 | |
| ToppCell | BAL-Mild-Myeloid-TRAM-TRAM3-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 1.23e-04 | 199 | 22 | 3 | af167e7a16c3537ce0aa821f608cdcb0c3abc07f | |
| ToppCell | BAL-Mild-Myeloid-TRAM-TRAM3-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09) | 1.23e-04 | 199 | 22 | 3 | 4b88ce864dc75ed8596a076ce4498f73639bbac8 | |
| ToppCell | BAL-Mild-Myeloid-TRAM|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09) | 1.23e-04 | 199 | 22 | 3 | 8a31a459491aa8625802c5211d38d57c1e8be76b | |
| ToppCell | BAL-Mild-Myeloid-TRAM|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 1.23e-04 | 199 | 22 | 3 | 27c63da6b29a1fc57ed2568443ba5029f3cdb186 | |
| ToppCell | mLN-Macrophage-LYVE1_Macrophage|Macrophage / Region, Cell class and subclass | 1.25e-04 | 200 | 22 | 3 | e3c15e0e1c2602b0cc9ab8cc50c978d265350c94 | |
| Disease | low density lipoprotein cholesterol measurement, physical activity | 1.11e-03 | 66 | 22 | 2 | EFO_0003940, EFO_0004611 | |
| Disease | serum alanine aminotransferase measurement, response to combination chemotherapy | 1.28e-03 | 71 | 22 | 2 | EFO_0004735, EFO_0007965 | |
| Disease | response to selective serotonin reuptake inhibitor | 1.70e-03 | 82 | 22 | 2 | EFO_0005658 | |
| Disease | liver fibrosis measurement | 1.87e-03 | 86 | 22 | 2 | EFO_0010576 | |
| Disease | platelet component distribution width | 2.15e-03 | 755 | 22 | 4 | EFO_0007984 | |
| Disease | low density lipoprotein cholesterol measurement, alcohol consumption measurement | 2.46e-03 | 99 | 22 | 2 | EFO_0004611, EFO_0007878 | |
| Disease | low density lipoprotein cholesterol measurement, alcohol drinking | 2.61e-03 | 102 | 22 | 2 | EFO_0004329, EFO_0004611 | |
| Disease | obsolete_red blood cell distribution width | 2.70e-03 | 1347 | 22 | 5 | EFO_0005192 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| ADYFKQWINLKKAYS | 266 | O43414 | |
| NSLWKGAYEYQGKKQ | 3276 | Q7Z408 | |
| TKWFGQRNKYFKTYN | 431 | Q8IYT2 | |
| LLNNYKKSWLYKAGS | 331 | Q9BV10 | |
| YDWSKGHEFYNPQKK | 336 | P78406 | |
| LKNAENEAYFKSWYQ | 796 | O75747 | |
| NEAYFKSWYQKLLAA | 801 | O75747 | |
| DKNNKLYLSYFNWRK | 306 | Q9Y231 | |
| QKLKWYFKLYDADGN | 91 | O95843 | |
| LFYNFDKNYKDWQSA | 1036 | P52701 | |
| IQWFKKFYDANYDGK | 151 | Q15555 | |
| GLEKFWAYLKYSQSK | 811 | Q659C4 | |
| KEGWNFYSNKCFKIF | 946 | P22897 | |
| NFCSKYGNWYMKAKN | 666 | P0C7P3 | |
| KSYKNLAFYWILKAG | 416 | Q9HB40 | |
| EKGNIKWNYKYDQLS | 126 | Q9Y286 | |
| YFKGKWNEQFDRKYT | 166 | P50452 | |
| WGYNDSKFIFNKKGQ | 96 | O00116 | |
| HYTAYAKNKLNGKWY | 881 | Q13107 | |
| AKNKLNGKWYYFDDS | 886 | Q13107 | |
| WKQRYYKNKFDVDAA | 516 | Q9H0D6 | |
| HYTAFAKNKDDGKWY | 891 | Q9Y4E8 | |
| AKNKDDGKWYYFDDS | 896 | Q9Y4E8 | |
| HAYKNNKWYLFNDAE | 2176 | Q70CQ2 | |
| WSKPQKDNKGYCAQY | 306 | O15146 |