Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioninositol 1,4,5-trisphosphate-gated calcium channel activity

ITPR1 ITPR2 ITPR3

1.14e-083463GO:0005220
GeneOntologyMolecularFunctioninositol 1,4,5 trisphosphate binding

PLCL2 ITPR1 ITPR2 ITPR3

2.43e-0814464GO:0070679
GeneOntologyMolecularFunctionintracellular sodium-activated potassium channel activity

KCNT2 KCNT1

5.19e-062462GO:0005228
GeneOntologyMolecularFunctionmonoatomic ion channel activity

TRPM6 KCNT2 TRPM7 KCNT1 SLC26A6 ITPR1 ITPR2 ITPR3

8.89e-06459468GO:0005216
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

ITPR1 ITPR2 ITPR3

9.11e-0618463GO:0015278
GeneOntologyMolecularFunctioncalcium channel activity

TRPM6 TRPM7 ITPR1 ITPR2 ITPR3

1.15e-05129465GO:0005262
GeneOntologyMolecularFunctionmonoatomic cation channel activity

TRPM6 KCNT2 TRPM7 KCNT1 ITPR1 ITPR2 ITPR3

1.25e-05343467GO:0005261
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

KCNT2 KCNT1 ITPR1 ITPR2 ITPR3

1.72e-05140465GO:0099094
GeneOntologyMolecularFunctionchannel activity

TRPM6 KCNT2 TRPM7 KCNT1 SLC26A6 ITPR1 ITPR2 ITPR3

2.34e-05525468GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

TRPM6 KCNT2 TRPM7 KCNT1 SLC26A6 ITPR1 ITPR2 ITPR3

2.38e-05526468GO:0022803
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

TRPM6 TRPM7 ITPR1 ITPR2 ITPR3

2.47e-05151465GO:0015085
GeneOntologyMolecularFunctionligand-gated calcium channel activity

ITPR1 ITPR2 ITPR3

4.92e-0531463GO:0099604
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

ITPR1 ITPR2 ITPR3

5.95e-0533463GO:0005217
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

KCNT2 KCNT1 ITPR1 ITPR2 ITPR3

7.96e-05193465GO:0015276
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

TRPM6 KCNT2 TRPM7 KCNT1 ITPR1 ITPR2 ITPR3

8.66e-05465467GO:0046873
GeneOntologyMolecularFunctionligand-gated channel activity

KCNT2 KCNT1 ITPR1 ITPR2 ITPR3

8.77e-05197465GO:0022834
GeneOntologyMolecularFunctionalcohol binding

PLCL2 ITPR1 ITPR2 ITPR3

8.88e-05102464GO:0043178
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

TRPM6 KCNT2 TRPM7 KCNT1 SLC26A6 ITPR1 ITPR2 ITPR3

3.02e-04758468GO:0015318
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

TRPM6 KCNT2 TRPM7 KCNT1 SLC26A6 ITPR1 ITPR2 ITPR3

4.08e-04793468GO:0015075
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

TRPM6 KCNT2 TRPM7 KCNT1 ITPR1 ITPR2 ITPR3

5.37e-04627467GO:0022890
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

TRPM6 KCNT2 TRPM7 KCNT1 ITPR1 ITPR2 ITPR3

7.54e-04664467GO:0008324
GeneOntologyMolecularFunctiongated channel activity

KCNT2 KCNT1 ITPR1 ITPR2 ITPR3

9.93e-04334465GO:0022836
GeneOntologyMolecularFunctiontransmembrane transporter activity

TRPM6 KCNT2 ABCA5 TRPM7 KCNT1 SLC26A6 ITPR1 ITPR2 ITPR3

1.29e-031180469GO:0022857
GeneOntologyMolecularFunctionoutward rectifier potassium channel activity

KCNT2 KCNT1

1.76e-0327462GO:0015271
GeneOntologyMolecularFunctionmonoatomic ion-gated channel activity

KCNT2 KCNT1

2.31e-0331462GO:0022839
GeneOntologyMolecularFunctiontransporter activity

TRPM6 KCNT2 ABCA5 TRPM7 KCNT1 SLC26A6 ITPR1 ITPR2 ITPR3

2.38e-031289469GO:0005215
GeneOntologyMolecularFunctionacetylgalactosaminyltransferase activity

ABO GBGT1

2.94e-0335462GO:0008376
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

CASP3 ERVK-19

3.28e-0337462GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

CASP3 ERVK-19

3.46e-0338462GO:0070001
GeneOntologyMolecularFunctionpeptidase activity

CASP3 ERVK-19 OTUB2 MASP1 CFAP44 ADAM7

3.71e-03654466GO:0008233
GeneOntologyBiologicalProcesscellular response to cAMP

SLC26A6 ITPR1 ITPR2 ITPR3

5.85e-0653464GO:0071320
GeneOntologyBiologicalProcessresponse to cAMP

SLC26A6 ITPR1 ITPR2 ITPR3

6.45e-0597464GO:0051591
GeneOntologyCellularComponentplatelet dense tubular network membrane

ITPR1 ITPR2 ITPR3

8.30e-079463GO:0031095
GeneOntologyCellularComponentplatelet dense tubular network

ITPR1 ITPR2 ITPR3

1.63e-0611463GO:0031094
GeneOntologyCellularComponentbrush border

TRPM6 FLNB SLC26A6 ITPR3

3.46e-04152464GO:0005903
GeneOntologyCellularComponentsarcoplasmic reticulum

ITPR1 ITPR2 ITPR3

9.60e-0488463GO:0016529
GeneOntologyCellularComponentcytoplasmic side of endoplasmic reticulum membrane

THADA ITPR3

1.06e-0322462GO:0098554
DomainInsP3_rcpt-bd

ITPR1 ITPR2 ITPR3

1.14e-083433IPR000493
DomainRIH_assoc

ITPR1 ITPR2 ITPR3

2.26e-076433PF08454
DomainRIH_assoc-dom

ITPR1 ITPR2 ITPR3

2.26e-076433IPR013662
DomainRYDR_ITPR

ITPR1 ITPR2 ITPR3

2.26e-076433PF01365
DomainRIH_dom

ITPR1 ITPR2 ITPR3

2.26e-076433IPR000699
DomainIns145_P3_rcpt

ITPR1 ITPR2 ITPR3

2.26e-076433IPR014821
DomainRyanodine_recept-rel

ITPR1 ITPR2 ITPR3

2.26e-076433IPR015925
DomainIns145_P3_rec

ITPR1 ITPR2 ITPR3

2.26e-076433PF08709
Domain-

ITPR1 ITPR2 ITPR3

2.26e-0764331.25.10.30
DomainMIR

ITPR1 ITPR2 ITPR3

1.35e-0610433PS50919
DomainMIR

ITPR1 ITPR2 ITPR3

1.35e-0610433PF02815
DomainMIR

ITPR1 ITPR2 ITPR3

1.35e-0610433SM00472
DomainMIR_motif

ITPR1 ITPR2 ITPR3

1.35e-0610433IPR016093
DomainIon_trans_dom

TRPM6 TRPM7 ITPR1 ITPR2 ITPR3

6.20e-06114435IPR005821
DomainIon_trans

TRPM6 TRPM7 ITPR1 ITPR2 ITPR3

6.20e-06114435PF00520
DomainTRPM_tetra

TRPM6 TRPM7

3.10e-054432PF16519
DomainGlyco_transf_6

ABO GBGT1

3.10e-054432PF03414
DomainK_chnl_Ca-activ_BK_asu

KCNT2 KCNT1

3.10e-054432IPR003929
DomainGlyco_trans_6

ABO GBGT1

3.10e-054432IPR005076
DomainTRPM_tetra

TRPM6 TRPM7

3.10e-054432IPR032415
DomainBK_channel_a

KCNT2 KCNT1

3.10e-054432PF03493
DomainMHCK_EF2_kinase

TRPM6 TRPM7

7.72e-056432IPR004166
DomainAlpha_kinase

TRPM6 TRPM7

7.72e-056432PF02816
DomainALPHA_KINASE

TRPM6 TRPM7

7.72e-056432PS51158
DomainAlpha_kinase

TRPM6 TRPM7

7.72e-056432SM00811
DomainK_chnl_dom

KCNT2 KCNT1

1.06e-0321432IPR013099
DomainIon_trans_2

KCNT2 KCNT1

1.06e-0321432PF07885
DomainActinin_actin-bd_CS

FLNB SYNE1

1.27e-0323432IPR001589
DomainACTININ_2

FLNB SYNE1

1.27e-0323432PS00020
DomainACTININ_1

FLNB SYNE1

1.27e-0323432PS00019
Domainzf-CCHC

RBM4B RBM4

1.27e-0323432PF00098
Domain-

RBM4B RBM4

1.62e-03264324.10.60.10
DomainZF_CCHC

RBM4B RBM4

2.94e-0335432PS50158
DomainABC_transporter_CS

ABCF2 ABCA5

4.20e-0342432IPR017871
DomainPRY

MID1 TRIM10

4.20e-0342432PF13765
DomainAAA+_ATPase

ABCF2 RUVBL1 ABCA5

4.42e-03144433IPR003593
DomainAAA

ABCF2 RUVBL1 ABCA5

4.42e-03144433SM00382
DomainPRY

MID1 TRIM10

5.46e-0348432SM00589
DomainPRY

MID1 TRIM10

5.46e-0348432IPR006574
DomainABC_TRANSPORTER_2

ABCF2 ABCA5

5.46e-0348432PS50893
DomainABC_tran

ABCF2 ABCA5

5.46e-0348432PF00005
DomainABC_TRANSPORTER_1

ABCF2 ABCA5

5.69e-0349432PS00211
DomainABC_transporter-like

ABCF2 ABCA5

5.91e-0350432IPR003439
DomainZnF_C2HC

RBM4B RBM4

7.12e-0355432SM00343
DomainZnf_CCHC

RBM4B RBM4

7.12e-0355432IPR001878
DomainARM-type_fold

THADA ODAD2 ITPR1 ITPR2

7.54e-03339434IPR016024
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

CASP3 ITPR1 ITPR2 ITPR3

1.35e-0719364M47760
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKN_TO_MGLUR1_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

1.52e-075363M49000
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

CASP3 ITPR1 ITPR2 ITPR3

2.54e-0722364M47690
PathwayKEGG_MEDICUS_REFERENCE_MGLUR5_CA2_APOPTOTIC_PATHWAY

CASP3 ITPR1 ITPR2 ITPR3

2.54e-0722364M47675
PathwayKEGG_MEDICUS_REFERENCE_CA2_PLCD_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

3.04e-076363M47960
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

CASP3 ITPR1 ITPR2 ITPR3

3.06e-0723364M47676
PathwayKEGG_MEDICUS_REFERENCE_BCR_PLCG_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

1.27e-069363M47852
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SPTBN2_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

1.81e-0610363M47661
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKCG_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

2.49e-0611363M49033
PathwayREACTOME_CLEC7A_DECTIN_1_INDUCES_NFAT_ACTIVATION

ITPR1 ITPR2 ITPR3

2.49e-0611363M27466
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

4.30e-0613363M47696
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_SIGMAR1_TO_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

4.30e-0613363M47751
PathwayKEGG_MEDICUS_REFERENCE_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

4.30e-0613363M47656
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

ITPR1 ITPR2 ITPR3

4.30e-0613363MM14553
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

ITPR1 ITPR2 ITPR3

8.37e-0616363M26945
PathwayREACTOME_VEGFR2_MEDIATED_CELL_PROLIFERATION

ITPR1 ITPR2 ITPR3

1.44e-0519363M27423
PathwayKEGG_MEDICUS_REFERENCE_TCR_PLCG_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

1.44e-0519363M47733
PathwayKEGG_MEDICUS_REFERENCE_MACHR_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

1.69e-0520363M47688
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MACHR_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

1.97e-0521363M47689
PathwayREACTOME_EFFECTS_OF_PIP2_HYDROLYSIS

ITPR1 ITPR2 ITPR3

3.38e-0525363MM14511
PathwayWP_ALZHEIMERS_DISEASE

CASP3 ITPR1 ITPR2 ITPR3

3.63e-0574364MM15962
PathwayREACTOME_EFFECTS_OF_PIP2_HYDROLYSIS

ITPR1 ITPR2 ITPR3

4.29e-0527363M12123
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

ITPR1 ITPR2 ITPR3

4.29e-0527363MM15053
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

ITPR1 ITPR2 ITPR3

4.80e-0528363M924
PathwayREACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION

ITPR1 ITPR2 ITPR3

7.21e-0532363MM14983
PathwaySIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES

ITPR1 ITPR2 ITPR3

1.03e-0436363M1315
PathwayWP_VITAMIN_DSENSITIVE_CALCIUM_SIGNALING_IN_DEPRESSION

ITPR1 ITPR2 ITPR3

1.03e-0436363M39831
PathwayREACTOME_CLEC7A_DECTIN_1_SIGNALING

CARD11 ITPR1 ITPR2 ITPR3

1.18e-04100364M27467
PathwayREACTOME_SIGNALING_BY_VEGF

NCKAP1 ITPR1 ITPR2 ITPR3

1.48e-04106364M27077
PathwayREACTOME_DAG_AND_IP3_SIGNALING

ITPR1 ITPR2 ITPR3

1.53e-0441363M512
PathwayREACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION

ITPR1 ITPR2 ITPR3

1.64e-0442363M791
PathwayWP_RENINANGIOTENSINALDOSTERONE_SYSTEM_RAAS

ITPR1 ITPR2 ITPR3

1.89e-0444363M39845
PathwaySIG_CHEMOTAXIS

ITPR1 ITPR2 ITPR3

2.02e-0445363M5193
PathwaySIG_BCR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

2.15e-0446363M8626
PathwayKEGG_MEDICUS_REFERENCE_GPCR_PLCB_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

2.76e-0450363M47951
PathwayREACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_BCR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS

ITPR1 ITPR2 ITPR3

3.28e-0453363MM15716
PathwayREACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR

CARD11 ITPR1 ITPR2 ITPR3

3.33e-04131364MM15717
PathwayREACTOME_ION_HOMEOSTASIS

ITPR1 ITPR2 ITPR3

3.47e-0454363M27460
PathwayREACTOME_ION_HOMEOSTASIS

ITPR1 ITPR2 ITPR3

3.47e-0454363MM15202
PathwayREACTOME_G_PROTEIN_MEDIATED_EVENTS

ITPR1 ITPR2 ITPR3

3.47e-0454363M26911
PathwayKEGG_MEDICUS_REFERENCE_RTK_PLCG_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

3.66e-0455363M47952
PathwayREACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS

CARD11 ITPR1 ITPR2 ITPR3

4.29e-04140364M27484
PathwayREACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS

NCKAP1 ITPR1 ITPR2 ITPR3

4.65e-04143364M27107
PathwayREACTOME_REGULATION_OF_INSULIN_SECRETION

ITPR1 ITPR2 ITPR3

4.97e-0461363MM15071
PathwayREACTOME_CA2_PATHWAY

ITPR1 ITPR2 ITPR3

5.22e-0462363M27321
PathwayKEGG_LONG_TERM_POTENTIATION

ITPR1 ITPR2 ITPR3

7.44e-0470363M3115
PathwayKEGG_LONG_TERM_DEPRESSION

ITPR1 ITPR2 ITPR3

7.44e-0470363M8232
PathwayREACTOME_INTEGRATION_OF_ENERGY_METABOLISM

ITPR1 ITPR2 ITPR3

8.08e-0472363MM14631
PathwayKEGG_ALZHEIMERS_DISEASE

CASP3 ITPR1 ITPR2 ITPR3

8.14e-04166364M16024
PathwayREACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR

CARD11 ITPR1 ITPR2 ITPR3

8.14e-04166364M608
PathwayWP_AFFECTED_PATHWAYS_IN_DUCHENNE_MUSCULAR_DYSTROPHY

ITPR1 ITPR2 ITPR3

8.75e-0474363M48080
PathwayREACTOME_PLATELET_HOMEOSTASIS

ITPR1 ITPR2 ITPR3

9.46e-0476363MM15051
PathwayKEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM

ITPR1 ITPR2 ITPR3

9.46e-0476363M9052
PathwayREACTOME_REGULATION_OF_INSULIN_SECRETION

ITPR1 ITPR2 ITPR3

1.02e-0378363M1921
PathwayREACTOME_ROLE_OF_PHOSPHOLIPIDS_IN_PHAGOCYTOSIS

ITPR1 ITPR2 ITPR3

1.18e-0382363M27110
PathwayREACTOME_FC_EPSILON_RECEPTOR_FCERI_SIGNALING

CARD11 ITPR1 ITPR2 ITPR3

1.24e-03186364M27175
PathwayREACTOME_FCERI_MEDIATED_CA_2_MOBILIZATION

ITPR1 ITPR2 ITPR3

1.35e-0386363M27206
PathwayREACTOME_PLATELET_HOMEOSTASIS

ITPR1 ITPR2 ITPR3

1.35e-0386363M916
PathwayREACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_BCR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS

ITPR1 ITPR2 ITPR3

1.35e-0386363M601
PathwayKEGG_GAP_JUNCTION

ITPR1 ITPR2 ITPR3

1.54e-0390363M4013
PathwayREACTOME_OPIOID_SIGNALLING

ITPR1 ITPR2 ITPR3

1.54e-0390363M6467
PathwayREACTOME_FCGR3A_MEDIATED_IL10_SYNTHESIS

ITPR1 ITPR2 ITPR3

1.80e-0395363M29842
PathwayREACTOME_INTERFERON_GAMMA_SIGNALING

GBP7 MID1 TRIM10

1.97e-0398363M965
PathwayKEGG_GNRH_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

2.15e-03101363M1979
PathwayREACTOME_LEISHMANIA_INFECTION

NCKAP1 ITPR1 ITPR2 ITPR3

2.26e-03219364M29836
PathwayREACTOME_CARDIAC_CONDUCTION

ITPR1 ITPR2 ITPR3

2.27e-03103363MM15196
PathwayREACTOME_TRP_CHANNELS

TRPM6 TRPM7

2.30e-0328362MM14943
PathwayREACTOME_TRP_CHANNELS

TRPM6 TRPM7

2.30e-0328362M27241
PathwayREACTOME_INTEGRATION_OF_ENERGY_METABOLISM

ITPR1 ITPR2 ITPR3

2.60e-03108363M17034
PathwayKEGG_OOCYTE_MEIOSIS

ITPR1 ITPR2 ITPR3

2.95e-03113363M16817
PathwayKEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION

ITPR1 ITPR2 ITPR3

3.10e-03115363M9387
PathwayWP_ALZHEIMERS_DISEASE

CASP3 ITPR1 ITPR2 ITPR3

4.25e-03261364M42565
PathwayREACTOME_CARDIAC_CONDUCTION

ITPR1 ITPR2 ITPR3

4.38e-03130363M27454
PathwayREACTOME_ANTI_INFLAMMATORY_RESPONSE_FAVOURING_LEISHMANIA_PARASITE_INFECTION

ITPR1 ITPR2 ITPR3

4.77e-03134363M29840
PathwayREACTOME_INTERFERON_SIGNALING

FLNB GBP7 MID1 TRIM10

4.98e-03273364M983
PathwayPID_NFAT_TFPATHWAY

CASP3 ITCH

5.86e-0345362M60
PathwayREACTOME_BETA_CATENIN_INDEPENDENT_WNT_SIGNALING

ITPR1 ITPR2 ITPR3

6.05e-03146363M27288
PathwayWP_CALCIUM_REGULATION_IN_CARDIAC_CELLS

ITPR1 ITPR2 ITPR3

6.17e-03147363MM15854
Pubmed

Evidence that type I, II, and III inositol 1,4,5-trisphosphate receptors can occur as integral plasma membrane proteins.

ITPR1 ITPR2 ITPR3

2.17e-09346310874040
Pubmed

Expression of inositol 1,4,5-trisphosphate receptors in mouse oocytes and early embryos: the type I isoform is upregulated in oocytes and downregulated after fertilization.

ITPR1 ITPR2 ITPR3

2.17e-0934639808793
Pubmed

Abnormal distribution of inositol 1,4,5-trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Duchenne dystrophy-derived cells.

ITPR1 ITPR2 ITPR3

2.17e-09346320395455
Pubmed

Inositol 1,4,5-trisphosphate receptors are autoantibody target antigens in patients with Sjögren's syndrome and other systemic rheumatic diseases.

ITPR1 ITPR2 ITPR3

2.17e-09346317437169
Pubmed

Type 2 and type 3 inositol 1,4,5-trisphosphate (IP3) receptors promote the differentiation of granule cell precursors in the postnatal cerebellum.

ITPR1 ITPR2 ITPR3

2.17e-09346318194433
Pubmed

Decreased olfactory mucus secretion and nasal abnormality in mice lacking type 2 and type 3 IP3 receptors.

ITPR1 ITPR2 ITPR3

2.17e-09346318547250
Pubmed

Inositol 1,4,5-trisphosphate receptor gene variants are related to the risk of breast cancer in a Chinese population.

ITPR1 ITPR2 ITPR3

2.17e-09346336350267
Pubmed

IP3 receptors regulate vascular smooth muscle contractility and hypertension.

ITPR1 ITPR2 ITPR3

2.17e-09346327777977
Pubmed

The versatility and universality of calcium signalling.

ITPR1 ITPR2 ITPR3

2.17e-09346311413485
Pubmed

Using concatenated subunits to investigate the functional consequences of heterotetrameric inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2 ITPR3

2.17e-09346326009177
Pubmed

Differential inositol 1,4,5-trisphosphate receptor signaling in a neuronal cell line.

ITPR1 ITPR2 ITPR3

2.17e-09346317581770
Pubmed

Predominant role of type 1 IP3 receptor in aortic vascular muscle contraction.

ITPR1 ITPR2 ITPR3

2.17e-09346318241669
Pubmed

Receptor-activated single channels in intact human platelets.

ITPR1 ITPR2 ITPR3

2.17e-0934631693919
Pubmed

Granulosa cells express three inositol 1,4,5-trisphosphate receptor isoforms: cytoplasmic and nuclear Ca2+ mobilization.

ITPR1 ITPR2 ITPR3

2.17e-09346319068129
Pubmed

Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits.

ITPR1 ITPR2 ITPR3

2.17e-09346323955339
Pubmed

Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells.

ITPR1 ITPR2 ITPR3

2.17e-09346331979185
Pubmed

Tsg101 regulates PI(4,5)P2/Ca(2+) signaling for HIV-1 Gag assembly.

ITPR1 ITPR2 ITPR3

2.17e-09346324904548
Pubmed

Molecular basis of the isoform-specific ligand-binding affinity of inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2 ITPR3

2.17e-09346317327232
Pubmed

Nuclear inositol 1,4,5-trisphosphate receptors regulate local Ca2+ transients and modulate cAMP response element binding protein phosphorylation.

ITPR1 ITPR2 ITPR3

2.17e-09346316014380
Pubmed

Knockdown of the type 2 and 3 inositol 1,4,5-trisphosphate receptors suppresses muscarinic antinociception in mice.

ITPR1 ITPR2 ITPR3

2.17e-09346317890015
Pubmed

Inositol 1, 4, 5-trisphosphate receptors and human left ventricular myocytes.

ITPR1 ITPR2 ITPR3

2.17e-09346323983250
Pubmed

Differential distribution of inositol trisphosphate receptor isoforms in mouse oocytes.

ITPR1 ITPR2 ITPR3

2.17e-0934639858485
Pubmed

Activation of the inositol (1,4,5)-triphosphate calcium gate receptor is required for HIV-1 Gag release.

ITPR1 ITPR2 ITPR3

2.17e-09346320427533
Pubmed

Loss of IP3R-dependent Ca2+ signalling in thymocytes leads to aberrant development and acute lymphoblastic leukemia.

ITPR1 ITPR2 ITPR3

8.65e-09446325215520
Pubmed

Inositol 1, 4, 5-trisphosphate receptor interacts with the SNARE domain of syntaxin 1B.

ITPR1 ITPR2 ITPR3

8.65e-09446321424589
Pubmed

Loss of IP3 Receptor-Mediated Ca2+ Release in Mouse B Cells Results in Abnormal B Cell Development and Function.

ITPR1 ITPR2 ITPR3

8.65e-09446328615414
Pubmed

Distinct localization and function of (1,4,5)IP(3) receptor subtypes and the (1,3,4,5)IP(4) receptor GAP1(IP4BP) in highly purified human platelet membranes.

ITPR1 ITPR2 ITPR3

8.65e-09446310828023
Pubmed

IP3R-mediated Ca2+ signals govern hematopoietic and cardiac divergence of Flk1+ cells via the calcineurin-NFATc3-Etv2 pathway.

ITPR1 ITPR2 ITPR3

8.65e-09446328419336
Pubmed

Alternative splice variants of hTrp4 differentially interact with the C-terminal portion of the inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2 ITPR3

8.65e-09446311163362
Pubmed

IP3R-mediated Ca2+ signaling controls B cell proliferation through metabolic reprogramming.

ITPR1 ITPR2 ITPR3

8.65e-09446335494252
Pubmed

InsP₃receptors and Orai channels in pancreatic acinar cells: co-localization and its consequences.

ITPR1 ITPR2 ITPR3

2.16e-08546321568942
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

ITPR1 ITPR2 ITPR3

4.32e-08646323463619
Pubmed

Sprouty2 regulates PI(4,5)P2/Ca2+ signaling and HIV-1 Gag release.

ITPR1 ITPR2 ITPR3

4.32e-08646321762810
Pubmed

A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.

ITPR1 ITPR2 ITPR3

4.32e-08646320519450
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

ITPR1 ITPR2 ITPR3

4.32e-08646325966694
Pubmed

IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.

ITPR1 ITPR2 ITPR3

4.32e-08646316844763
Pubmed

LARK activates posttranscriptional expression of an essential mammalian clock protein, PERIOD1.

RBM14 RBM4B RBM4

7.55e-08746317264215
Pubmed

Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.

ITPR1 ITPR2 ITPR3

7.55e-08746311860456
Pubmed

Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes.

ITPR1 ITPR2 ITPR3

7.55e-08746322495310
Pubmed

Activation of TrkB signaling mitigates cerebellar anomalies caused by Rbm4-Bdnf deficiency.

CASP3 RBM4B RBM4

1.81e-07946337670183
Pubmed

Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU.

ITPR1 ITPR2 ITPR3

1.81e-07946325737585
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

TRPM7 ITPR1 ITPR2 ITPR3

1.91e-073846430786075
Pubmed

Type 1 and 3 inositol trisphosphate receptors are required for extra-embryonic vascular development.

ITPR1 ITPR2 ITPR3

3.55e-071146327514653
Pubmed

Evidence That ITPR2-Mediated Intracellular Calcium Release in Oligodendrocytes Regulates the Development of Carbonic Anhydrase II + Type I/II Oligodendrocytes and the Sizes of Myelin Fibers.

ITPR1 ITPR2 ITPR3

7.80e-071446334630045
Pubmed

Synergistic Signaling by Light and Acetylcholine in Mouse Iris Sphincter Muscle.

ITPR1 ITPR2 ITPR3

9.74e-071546328578927
Pubmed

Cell volume changes regulate slick (Slo2.1), but not slack (Slo2.2) K+ channels.

KCNT2 KCNT1

1.71e-06246225347289
Pubmed

The channel kinases TRPM6 and TRPM7 are functionally nonredundant.

TRPM6 TRPM7

1.71e-06246216150690
Pubmed

TRPM6 and TRPM7 differentially contribute to the relief of heteromeric TRPM6/7 channels from inhibition by cytosolic Mg2+ and Mg·ATP.

TRPM6 TRPM7

1.71e-06246228821869
Pubmed

Functional characterization of homo- and heteromeric channel kinases TRPM6 and TRPM7.

TRPM6 TRPM7

1.71e-06246216636202
Pubmed

Isoform diversity of the inositol trisphosphate receptor in cell types of mouse origin.

ITPR2 ITPR3

1.71e-0624629065779
Pubmed

Molecular mechanisms of Slo2 K+ channel closure.

KCNT2 KCNT1

1.71e-06246227682982
Pubmed

Expression of IP3 receptor isoforms at the nodes of Ranvier in rat sciatic nerve.

ITPR2 ITPR3

1.71e-06246217496801
Pubmed

Recent developments in intestinal magnesium absorption.

TRPM6 TRPM7

1.71e-06246218301276
Pubmed

Mutational analysis of the ligand binding site of the inositol 1,4,5-trisphosphate receptor.

ITPR1 ITPR3

1.71e-0624628663526
Pubmed

The alpha-kinases TRPM6 and TRPM7, but not eEF-2 kinase, phosphorylate the assembly domain of myosin IIA, IIB and IIC.

TRPM6 TRPM7

1.71e-06246218675813
Pubmed

The LARK/RBM4a protein is highly expressed in cerebellum as compared to cerebrum.

RBM4B RBM4

1.71e-06246218708123
Pubmed

The Pro335 --> Leu polymorphism of type 3 inositol 1,4,5-trisphosphate receptor found in mouse inbred lines results in functional change.

ITPR1 ITPR3

1.71e-06246215890645
Pubmed

Mice lacking inositol 1,4,5-trisphosphate receptors exhibit dry eye.

ITPR2 ITPR3

1.71e-06246224901844
Pubmed

TRPM6 kinase activity regulates TRPM7 trafficking and inhibits cellular growth under hypomagnesic conditions.

TRPM6 TRPM7

1.71e-06246224858416
Pubmed

Adrenergic inhibition facilitates normalization of extracellular potassium after cortical spreading depolarization.

ITPR2 ITPR3

1.71e-06246233854148
Pubmed

Mass Spectrometric Analysis of TRPM6 and TRPM7 Phosphorylation Reveals Regulatory Mechanisms of the Channel-Kinases.

TRPM6 TRPM7

1.71e-06246228220887
Pubmed

An antidepressant behaviour in mice carrying a gene-specific InsP3R1, InsP3R2 and InsP3R3 protein knockdown.

ITPR1 ITPR2

1.71e-06246218708078
Pubmed

Immunolocalization of type 2 inositol 1,4,5-trisphosphate receptors in cardiac myocytes from newborn mice.

ITPR1 ITPR2

1.71e-06246215201137
Pubmed

Pancreatic protease activation by alcohol metabolite depends on Ca2+ release via acid store IP3 receptors.

ITPR2 ITPR3

1.71e-06246219528657
Pubmed

Common genetic variants of the ion channel transient receptor potential membrane melastatin 6 and 7 (TRPM6 and TRPM7), magnesium intake, and risk of type 2 diabetes in women.

TRPM6 TRPM7

1.71e-06246219149903
Pubmed

Determination of relative amounts of inositol trisphosphate receptor mRNA isoforms by ratio polymerase chain reaction.

ITPR2 ITPR3

1.71e-0624628063813
Pubmed

Cloning and characterization of human type 2 and type 3 inositol 1,4,5-trisphosphate receptors.

ITPR2 ITPR3

1.71e-0624628081734
Pubmed

Massive autophosphorylation of the Ser/Thr-rich domain controls protein kinase activity of TRPM6 and TRPM7.

TRPM6 TRPM7

1.71e-06246218365021
Pubmed

Sulphide signalling potentiates apoptosis through the up-regulation of IP3 receptor types 1 and 2.

ITPR1 ITPR2

1.71e-06246223582047
Pubmed

Three additional inositol 1,4,5-trisphosphate receptors: molecular cloning and differential localization in brain and peripheral tissues.

ITPR1 ITPR3

1.71e-0624621374893
Pubmed

Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia.

TRPM6 TRPM7

1.71e-06246214976260
Pubmed

Slack and Slick K(Na) channels regulate the accuracy of timing of auditory neurons.

KCNT2 KCNT1

1.71e-06246217344399
Pubmed

Transient receptor potential melastatin 6 and 7 channels, magnesium transport, and vascular biology: implications in hypertension.

TRPM6 TRPM7

1.71e-06246218192217
Pubmed

Phylogenetic and molecular characterization of the splicing factor RBM4.

RBM4B RBM4

1.71e-06246223527094
Pubmed

Differential distribution of the sodium-activated potassium channels slick and slack in mouse brain.

KCNT2 KCNT1

1.71e-06246226587966
Pubmed

IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism.

ITPR2 ITPR3

1.71e-06246216195467
Pubmed

Dysregulation of renal transient receptor potential melastatin 6/7 but not paracellin-1 in aldosterone-induced hypertension and kidney damage in a model of hereditary hypomagnesemia.

TRPM6 TRPM7

1.71e-06246221602712
Pubmed

Magnesium homeostasis in colon carcinoma LoVo cells sensitive or resistant to doxorubicin.

TRPM6 TRPM7

1.71e-06246226563869
Pubmed

Caspase 3 cleavage of the inositol 1,4,5-trisphosphate receptor does not contribute to apoptotic calcium release.

CASP3 ITPR1

1.71e-06246223122728
Pubmed

The Different Roles of The Channel-Kinases TRPM6 and TRPM7.

TRPM6 TRPM7

1.71e-06246226179995
Pubmed

Essential role for TRPM6 in epithelial magnesium transport and body magnesium homeostasis.

TRPM6 TRPM7

1.71e-06246216075242
Pubmed

Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant.

ITPR2 ITPR3

1.71e-06246215632133
Pubmed

Evidence for the expression of TRPM6 and TRPM7 in cardiomyocytes from all four chamber walls of the human heart.

TRPM6 TRPM7

1.71e-06246234326388
Pubmed

Tyr-167/Trp-168 in type 1/3 inositol 1,4,5-trisphosphate receptor mediates functional coupling between ligand binding and channel opening.

ITPR1 ITPR3

1.71e-06246220813840
Pubmed

Inositol (1,4,5)-trisphosphate receptor links to filamentous actin are important for generating local Ca2+ signals in pancreatic acinar cells.

ITPR2 ITPR3

1.71e-06246215713744
Pubmed

Role of caspase-3 cleaved IP3 R1 on Ca(2+) homeostasis and developmental competence of mouse oocytes and eggs.

CASP3 ITPR1

1.71e-06246224692207
Pubmed

Heteroligomers of type-I and type-III inositol trisphosphate receptors in WB rat liver epithelial cells.

ITPR1 ITPR3

1.71e-0624627559486
Pubmed

Sodium-activated potassium channels shape peripheral auditory function and activity of the primary auditory neurons in mice.

KCNT2 KCNT1

1.71e-06246230796290
Pubmed

Differential mRNA expression and glucocorticoid-mediated regulation of TRPM6 and TRPM7 in the heart and kidney throughout murine pregnancy and development.

TRPM6 TRPM7

1.71e-06246225692682
Pubmed

TRPM6 is Essential for Magnesium Uptake and Epithelial Cell Function in the Colon.

TRPM6 TRPM7

1.71e-06246229912157
Pubmed

Structural studies of inositol 1,4,5-trisphosphate receptor: coupling ligand binding to channel gating.

ITPR1 ITPR3

1.71e-06246220843799
Pubmed

Magnesium and its transporters in cancer: a novel paradigm in tumour development.

TRPM6 TRPM7

1.71e-06246222671428
Pubmed

Type 1 and 2 IP3 receptors respond differently to catecholamines and stress.

ITPR1 ITPR2

1.71e-06246219120126
Pubmed

The TRPM6 kinase domain determines the Mg·ATP sensitivity of TRPM7/M6 heteromeric ion channels.

TRPM6 TRPM7

1.71e-06246224385424
Pubmed

Cardiac Slo2.1 Is Required for Volatile Anesthetic Stimulation of K+ Transport and Anesthetic Preconditioning.

KCNT2 KCNT1

1.71e-06246226845140
Pubmed

Gene variation of the transient receptor potential cation channel, subfamily M, members 6 (TRPM6) and 7 (TRPM7), and type 2 diabetes mellitus: a case-control study.

TRPM6 TRPM7

1.71e-06246220875900
Pubmed

Distinct roles of inositol 1,4,5-trisphosphate receptor types 1 and 3 in Ca2+ signaling.

ITPR1 ITPR3

1.71e-06246214707143
Pubmed

The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity.

ITPR1 ITPR2 ITPR3

3.28e-062246311696558
Pubmed

A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.

RBM14 GAN FLNB THADA ITPR1 ITPR2 ITPR3

4.17e-0650346736217030
Pubmed

Release of calcium from inositol 1,4,5-trisphosphate receptor-regulated stores by HIV-1 Tat regulates TNF-alpha production in human macrophages.

ITPR1 ITPR2 ITPR3

4.30e-062446310843712
InteractionIRAG1 interactions

GTF2I ITPR1 ITPR2 ITPR3

2.14e-0814454int:IRAG1
InteractionTRPC4 interactions

ITCH ITPR1 ITPR2 ITPR3

1.86e-0723454int:TRPC4
InteractionTESPA1 interactions

ITPR1 ITPR2 ITPR3

5.71e-0616453int:TESPA1
InteractionCFAP44 interactions

GAN GTF2I CFAP44

6.92e-0617453int:CFAP44
InteractionRASEF interactions

ITPR1 ITPR2 ITPR3

2.31e-0525453int:RASEF
InteractionBBOX1 interactions

ITPR1 ITPR2 ITPR3

3.65e-0529453int:BBOX1
InteractionTRPC1 interactions

ITPR1 ITPR2 ITPR3

3.65e-0529453int:TRPC1
InteractionRPN2 interactions

RBM14 MASP1 NCKAP1 TRPM7 RBM4B SYNE1 ITPR1 ITPR2 ITPR3

4.81e-05782459int:RPN2
InteractionTRPC2 interactions

ITPR1 ITPR3

4.85e-055452int:TRPC2
InteractionC3orf52 interactions

KCNT2 ABCA5 TRPM7 LCLAT1 ITPR2 ITPR3

5.67e-05305456int:C3orf52
InteractionUBE2L6 interactions

ABCF2 ITCH RUVBL1 MID1

1.29e-04116454int:UBE2L6
InteractionTRPM6 interactions

TRPM6 TRPM7

1.35e-048452int:TRPM6
GeneFamilyInositol 1,4,5-triphosphate receptors|Protein phosphatase 1 regulatory subunits

ITPR1 ITPR2 ITPR3

7.89e-093373297
GeneFamilyPotassium sodium-activated channel subfamily T

KCNT2 KCNT1

4.08e-062372856
GeneFamilyGlycosyltransferase family 6|Blood group antigens

ABO GBGT1

2.44e-054372429
GeneFamilyZinc fingers CCHC-type|RNA binding motif containing

RBM4B RBM4

1.19e-032537274
GeneFamilyTransient receptor potential cation channels

TRPM6 TRPM7

1.49e-0328372249
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

THADA ODAD2

3.49e-0343372409
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

KNL1 ITPR1 ITPR3

5.97e-03181373694
GeneFamilyRNA binding motif containing

RBM14 RBM4B RBM4

9.33e-03213373725
CoexpressionGSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_DN

RBM14 CASP3 FAM83G MINPP1 DROSHA KNL1

1.13e-06199456M8113
CoexpressionGSE22589_HEALTHY_VS_SIV_INFECTED_DC_DN

CASP3 MINPP1 GBP7 PLCL2 ITPR2

2.29e-05199455M7809
CoexpressionGSE40273_XBP1_KO_VS_WT_TREG_DN

GAN FLNB ABCA5 SYNE1 ITPR2

2.29e-05199455M9124
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 CCDC178 TRPM7 MID1 ITPR1

1.01e-06179455666072c0e8448dbaec1683d18368ec2502453f90
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 CCDC178 ABCA5 TRPM7 ITPR1

1.10e-061824555f513bbb7125956eb528e3120de3fd776770a7c3
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 GTF2I ABCA5 TRPM7 ITPR1

1.13e-061834552f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 CCDC178 ABCA5 TRPM7 ITPR1

1.13e-061834552e831a4d99c6f983793df71c0994124c943c6da9
ToppCellCOVID-19-kidney-DCT|kidney / Disease (COVID-19 only), tissue and cell type

TRPM6 CCDC178 ABCA5 TRPM7 ITPR1

1.29e-06188455df1fd0819d301679f3c9ea404e942e39095912eb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 CCDC178 ABCA5 TRPM7 ITPR1

1.32e-06189455f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 CCDC178 ABCA5 TRPM7 ITPR1

1.32e-061894557eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 CCDC178 ABCA5 TRPM7 ITPR1

1.32e-06189455975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 CCDC178 ABCA5 TRPM7 ITPR1

1.36e-06190455b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 GTF2I ABCA5 TRPM7 ITPR1

1.54e-06195455a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CFAP54 ODAD2 RUVBL1 CFAP44 SYNE1

1.62e-06197455d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CFAP54 ODAD2 RUVBL1 CFAP44 SYNE1

1.62e-06197455e453d085182364ca347cbcc9dc995c62c3353016
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 CCDC178 ABCA5 ITPR1

1.11e-0513745485b3a98039c1f68addad0334aa5b2584f6045aaa
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 ABCA5 TRPM7 ITPR1

2.05e-051604542d391ba6f7adb55dfa89feecc10cc9ce97e5fe74
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 ABCA5 TRPM7 ITPR1

2.05e-051604548bcdbcfdf1e0ace6053e8de82762f6e2f86bba7a
ToppCellPND01-03-samps-Myeloid-Macrophage-CD163+_Macrophage|PND01-03-samps / Age Group, Lineage, Cell class and subclass

OTUB2 KNL1 TRIM10 GBGT1

2.05e-051604544480a7d6bd48d06b4e5196faac868f31ab7ed3ad
ToppCellCOVID-19-kidney-PEC|kidney / Disease (COVID-19 only), tissue and cell type

CFAP54 ODAD2 KCNT2 SYNE1

2.72e-0517245436a96714a0eb6ac438648135336c9791881ddadb
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 ABCA5 TRPM7 ITPR1

2.78e-051734540c74bdb40e635d906fd180412c23bf7fed61621e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 CCDC178 TRPM7 ITPR1

2.91e-05175454787ac1a12cda10af5c8830471702a4cbaf43e79e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 ABCA5 TRPM7 ITPR1

3.04e-05177454dc846d0feb94d4c289553cc3ac9dac81d10409cb
ToppCellPericytes-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

FLNB MASP1 KCNT2 KCNT1

3.32e-0518145435c470988a93381eefa300831aabb813fa1b90bd
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 ABCA5 TRPM7 ITPR1

3.32e-05181454e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 FLNB CCDC178 ABCA5

3.77e-05187454f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 ABCA5 TRPM7 ITPR1

3.85e-05188454eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 ABCA5 TRPM7 ITPR1

3.85e-05188454bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

FLNB KCNT2 MID1 ITPR1

3.93e-051894546b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 FLNB CCDC178 ABCA5

3.93e-05189454e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 ABCA5 TRPM7 ITPR1

3.93e-05189454977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC178 CFAP54 SYNE1 ITPR3

4.01e-051904543fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 ABCA5 TRPM7 ITPR1

4.01e-05190454e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

CFAP54 ODAD2 CFAP44 SYNE1

4.18e-05192454be592e661367affced9ebe80849b466e6adb3a34
ToppCellCOVID-19-kidney-CNT|kidney / Disease (COVID-19 only), tissue and cell type

TRPM6 CCDC178 MID1 ITPR1

4.18e-05192454d32ae226d95b4b6adb99d14b602be09b661d4cd9
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 ABCA5 TRPM7 ITPR1

4.18e-0519245446ea8f4f292db70420b378c6fa3e55e99413679c
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CFAP54 ODAD2 CFAP44 SYNE1

4.26e-051934540b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 ABCA5 TRPM7 ITPR1

4.26e-05193454dd9874898587fe9fd9cf2aebc2e0579dcf06944e
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

CFAP54 ODAD2 CFAP44 SYNE1

4.26e-05193454ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 ABCA5 TRPM7 ITPR1

4.35e-05194454f08a7618a9ccf12e4a7620235ae662a8abc521af
ToppCellASK440-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

CFAP54 ODAD2 RUVBL1 CFAP44

4.35e-05194454c84a7fa94fb06e08aae04db56c8c313b0afde1d7
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 ABCA5 TRPM7 ITPR1

4.44e-0519545460d08fb27469d1e247bc47b651d7023ba82cf92f
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CFAP54 ODAD2 CFAP44 SYNE1

4.44e-051954543486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

CFAP54 ODAD2 NCKAP1 SYNE1

4.53e-051964546d02d494196e3f857d53eea46d9419690d43beca
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP54 ODAD2 CFAP44 SYNE1

4.53e-05196454d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

CFAP54 ODAD2 NCKAP1 SYNE1

4.53e-05196454af4cdc61830685a888a1209826c23bcf54a43084
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP54 ODAD2 CFAP44 SYNE1

4.62e-051974546865f4831eb23794fb88a8649d48d497bbae3f44
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP54 ODAD2 CFAP44 SYNE1

4.62e-0519745471fea4aa6ce96c7693fa94792d08770622873850
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CFAP54 ODAD2 CFAP44 SYNE1

4.71e-05198454ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellBronchus_Control_(B.)-Epithelial-TX-Ciliated|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

CFAP54 ODAD2 CFAP44 SYNE1

4.89e-052004546a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal-Unfolded_protein_responsible_cell|GW12 / Sample Type, Dataset, Time_group, and Cell type.

OTUB2 ABCA5 SLC26A6 PLCL2

4.89e-052004546b7314c425f6b40f1301dd39cc02b0436e96a2ec
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

FAM83G ADAM7 ITPR3

1.50e-041024532c3622fc3cd62d9b7e185d0204cf7f03e7dde73c
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Myh4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MASP1 CCDC178 ABO

2.99e-04129453f83187c0bb06528127b8d2d56674ab1946846951
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 ABCA5 ITPR1

3.96e-041424535b6b0c611c83b23ef7289854a515b78f6cf84500
ToppCellP03-Hematopoietic-Erythroid|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CFAP54 DROSHA TRIM10

4.13e-041444532ee6a834860eac7ed004f366ab4fc38c4b80c905
ToppCellP03-Hematopoietic-Erythroid-enucleate_erythrocyte|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CFAP54 DROSHA TRIM10

4.13e-041444539fa63904389f4d7163db22ea85ab721d8f6e8d99
ToppCell368C-Myeloid-Macrophage-FABP4+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

CFAP54 RUVBL1 ITPR1

4.30e-041464535b2608b56204dda9a773988f42ff00a9fa743a39
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-9|TCGA-Liver / Sample_Type by Project: Shred V9

GBP7 KNL1 PLCL2

4.47e-04148453683b2b80ee389469d948aaf6a77632b24f56e989
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ODAD2 KCNT2 SYNE1

4.56e-0414945324a7538b54b2a5291503c7493fefed4e45e8d710
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ODAD2 KCNT2 SYNE1

4.56e-04149453cc6224c6b79f43b97adc1ce48ca4906bff2ad318
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 CCDC178 MID1

4.93e-041534539b6675ace8a83c8d446b722301d0ec4e6840f3fc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 ABCA5 TRPM7

4.93e-0415345398670bbce4a770af244f033cdd2d54db57200ca8
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP54 ODAD2 CFAP44

5.02e-0415445358072ce422d09f2de602580325eaac6c4ec6c136
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP54 ODAD2 CFAP44

5.02e-041544539ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP54 ODAD2 CFAP44

5.12e-041554535f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP54 ODAD2 CFAP44

5.12e-041554530944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 ABCA5 TRPM7

5.21e-041564534d2679e7639758c49fc25a2deb9109b08f0a3e57
ToppCell10x3'2.3-week_12-13-Hematopoietic-HSC/MPP_and_pro-pDC_progenitor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

IRAK1BP1 CARD11 ITPR3

5.31e-0415745362f029831c420d3e9580822177545eb7fdf4d0a3
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 CCDC178 MID1

5.31e-041574532c5295043611bac7dfa4aef2146681bce4a33a8f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MASP1 KCNT2 SYNE1

5.41e-04158453e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 ABCA5 ITPR1

5.41e-041584537960337d87afecf2692ab65e5991f052ceddfacc
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MASP1 KCNT2 SYNE1

5.41e-04158453d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 ABCA5 RBM4B

5.61e-0416045386fde32f096eaf9ea3677f57169cdcc0a57bb8dd
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 ABCA5 ITPR1

5.82e-0416245336ddebe3bb172c992739353b7b049b2dde98b559
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCDC178 ABCA5 ADAM7

5.82e-04162453bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ODAD2 CFAP44 MID1

6.03e-04164453d9531848105d606adedde65426177cf851140e31
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

CFAP54 RUVBL1 CFAP44

6.36e-0416745326cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE1 KNL1 TRIM10

6.36e-041674531bd27ffe381d26731b6d4cc5f29b27f1bac4473b
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MASP1 SLC26A6 ITPR1

6.36e-0416745391b14df450bfb6a2b406c88f8c75cd51eeb9e82b
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE1 KNL1 TRIM10

6.47e-04168453faaba5ac01c2ebe380f56559374a121979a85a13
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP54 ODAD2 CFAP44

6.58e-0416945314aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellfacs-Marrow-T-cells-3m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CARD11 ABCA5 ITPR1

6.81e-041714536a0fafb8fd9fc7671618eeb2bf528ce8ce86b794
ToppCellfacs-Marrow-T-cells-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CARD11 ABCA5 ITPR1

6.81e-04171453e02b5831768dbb1b68998b672e55c9680ab0cc86
ToppCelldroplet-Marrow-BM_(NON-STC)-30m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE1 KNL1 TRIM10

6.92e-0417245331c5710fd7ebb221e703545595f5ec0ee3a32bcf
ToppCellCiliated_cells-B-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

CFAP54 ODAD2 CFAP44

6.92e-04172453187ae91148d293537afc77e10da2b64302322224
ToppCelldroplet-Marrow-BM_(NON-STC)|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE1 KNL1 TRIM10

6.92e-041724536004327045f03d832fdabe6cb2f8b1b1db57789a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 ABCA5 TRPM7

7.04e-041734534bc6d93716f093b460c8b047199db8cab5fea720
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

POLI FLNB ITPR3

7.04e-041734534968712af1cca8c932abd3323631d7dcaffd4a66
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ODAD2 ABCA5 ITPR2

7.28e-041754531d8da48236549c01381f777ce5b2937f9f86acc2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA5 ITPR1 ITPR2

7.28e-0417545377c16e615c0fb9c83f29d7e0a547be72635fac81
ToppCellfacs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CARD11 ABCA5 ITPR1

7.40e-0417645374f851a398c7562dd713bc0d8d488c0037243112
ToppCellfacs-Marrow-T_cells-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CARD11 ABCA5 ITPR1

7.40e-0417645331b5459a978d5cdde0af03a77401e0464d8c95ba
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP54 ODAD2 CFAP44

7.52e-04177453ae01c19403a09f7ba5e4beafdfcd1b8eebdadcb7
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

THADA NCKAP1 SLC26A6

7.52e-0417745336b5d29caa9cffbc0284f771a4db71aa72171a89
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP54 ODAD2 CFAP44

7.52e-04177453bd3d07bdef6e903995d4bbfb6ff3a5e1d9fb70cc
ToppCell10x5'v1-week_17-19-Hematopoietic-HSC/MPP_and_pro-MEP|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

OTUB2 CFAP54 MINPP1

7.65e-04178453b8c301d65c0f37941e8e9414d55e90edb6ecc195
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNT1 ADAM7 ITPR1

7.77e-04179453a3922476f33d2e4137a12dbda21a1703dff79684
ToppCell10x5'v1-week_17-19-Hematopoietic-erythroid-early_erythroid|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MINPP1 ABO GBGT1

7.77e-041794533f73f89905c061ada4e3eb921fa394d95f95c959
ToppCellCOVID-19-kidney-Epi_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

CFAP54 KCNT2 SYNE1

7.77e-04179453e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCelldroplet-Bladder-Unstain-18m-Epithelial-granulocyte-monocyte_progenitor|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNL1 TRIM10 PLCL2

7.77e-04179453804aa3899585fc7e662eff9f6d41f48655f16dd6
ToppCellLV|World / Chamber and Cluster_Paper

TRPM7 LCLAT1 PLCL2

7.90e-041804535ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FLNB THADA NCKAP1

7.90e-04180453a682a5d55c612709c9ee9fa4289d6f8bef7fe1af
ToppCellfacs-Marrow-B-cells-3m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CARD11 ABCA5 ITPR1

7.90e-04180453bf8d13d4db1af55b8c9fe16aaccf8743e000e005
Drug2-aminoethoxydiphenyl borate

CASP3 TRPM7 ITPR1 ITPR2 ITPR3

1.31e-0761455ctd:C109986
Drugtrimethylphosphine

POLI DROSHA SYNE1 MID1

3.51e-0730454CID000068983
Drugmag-fura-2

TRPM6 TRPM7 ITPR1 ITPR3

8.38e-0737454CID000123839
Drugadenophostin A

ITPR2 ITPR3

3.82e-062452ctd:C085029
DrugIsocaffeine

ITPR1 ITPR3

3.82e-062452CID000001326
Drugadenophostin B

ITPR1 ITPR3

3.82e-062452CID000656722
Drugbenzene 1,2,4-trisphosphate

ITPR1 ITPR3

3.82e-062452CID000192376
Drugs-BuLi

POLI SYNE1 MID1

4.81e-0617453CID000061028
Drugphenylacetylene

POLI GAN MID1

8.03e-0620453CID000010821
Drugtetrafluoroborate

POLI SYNE1 MID1

1.08e-0522453CID000026255
Drug5-deoxy-5-fluoro-myo-inositol

ITPR1 ITPR3

1.14e-053452CID000195110
Drugmagnesium oxide

TRPM6 GAN MID1

1.24e-0523453CID000014792
DrugNSC-131122

CASP3 ABO GBGT1

1.42e-0524453CID000005133
Drug9-aminoacridine

POLI SYNE1 ITPR1 ITPR3

1.80e-0579454CID000007019
Drugbutadiynyl

SYNE1 MID1

2.29e-054452CID000521459
Drugtriphenylphosphine sulfide

POLI MID1

2.29e-054452CID000019758
DrugCHEBI:697555

ITPR1 ITPR3

2.29e-054452CID009578246
Drug1,2-bis(dicyclohexylphosphino)ethane

POLI MID1

2.29e-054452CID000534202
Drugsodium acetylacetonate

POLI GAN SYNE1

3.78e-0533453CID000018630
DrugtBuNC

POLI SYNE1

3.81e-055452CID000023577
Drug17-AAG; Down 200; 1uM; PC3; HT_HG-U133A

RBM14 ABCF2 OTUB2 CFAP44 SLC26A6

3.95e-051944551226_DN
Drugborate

TRPM6 TRPM7 ITPR1 ITPR3

4.20e-0598454CID000007628
DrugBetaxolol hydrochloride [63659-19-8]; Down 200; 11.6uM; PC3; HT_HG-U133A

ABCF2 OTUB2 THADA SYNE1 ITPR1

4.25e-051974554608_DN
DrugAC1Q7BER

ITPR1 ITPR3

5.70e-056452CID000005702
DrugAC1L98DX

CASP3 ITPR1 ITPR3

5.80e-0538453CID000439957
Drugdiphosphine

POLI SYNE1 MID1

6.27e-0539453CID000139283
Drugmethyl-ene

POLI SYNE1 MID1

7.30e-0541453CID000123164
Drug3-F-InsP3

ITPR1 ITPR3

7.97e-057452CID003035756
DrugBr2BAPTA

ITPR1 ITPR3

7.97e-057452CID003081001
Drug[[(2R,3S,4R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl hydrogen phosphate

ITPR1 ITPR3

7.97e-057452CID009547999
Drugs-tetrazine

SYNE1 MID1

7.97e-057452CID000009263
Drug$l^{1}-borane

POLI ITPR1 ITPR3

9.03e-0544453CID006397184
Drug9 mM of H

ITPR1 ITPR3

1.06e-048452CID000130464
Drug2,3-diene

POLI SYNE1

1.06e-048452CID000010566
Drugbasic copper carbonate

ITPR1 ITPR3

1.06e-048452CID000025503
DrugNs 004

ITPR1 ITPR3

1.06e-048452CID000162750
DrugF2 g

ITPR1 ITPR3

1.06e-048452CID006857713
Drugzinc protoporphyrin

CASP3 CARD11 ITPR1 ITPR3

1.12e-04126454CID000027287
DrugZ)-combretastatin A-4

POLI CASP3 SYNE1

1.33e-0450453CID000072686
Drugcumulene

SYNE1 MID1

1.36e-049452CID006324998
Drugmanganese

CASP3 CARD11 ABO TRPM7 DROSHA ITPR1 GBGT1 ITPR3

1.41e-04791458CID000023930
DrugUTP-NA

CASP3 CARD11 ABO ITPR1 GBGT1 ITPR3

1.68e-04420456CID000001181
Drugclausenamide

ITPR1 ITPR3

1.70e-0410452CID000128412
Drugisobutyllithium

GAN SYNE1

1.70e-0410452CID000141200
Drugsilyl ethers

POLI SYNE1

1.70e-0410452CID006327522
DrugVanadates

CASP3 IRAK1BP1 GAN FLNB OTUB2 CARD11 ODAD2 ABCA5 MID1 GBGT1

1.83e-0413024510ctd:D014638
DrugR 478

ITPR1 ITPR3

2.08e-0411452CID000084223
Drug8-amino-cADPR

ITPR1 ITPR3

2.08e-0411452CID003081323
Drugpentenone

POLI SYNE1

2.08e-0411452CID000015394
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

ITPR1 ITPR2 ITPR3

6.28e-0712433DOID:1441 (implicated_via_orthology)
DiseaseAnoxic Encephalopathy

ITPR1 ITPR2

2.07e-062432C0003132
DiseaseBrain Hypoxia

ITPR1 ITPR2

2.07e-062432C1527348
DiseaseAnoxia of brain

ITPR1 ITPR2

2.07e-062432C0995195
DiseaseHypoxic Brain Damage

ITPR1 ITPR2

2.07e-062432C1140716
Diseasedigestive system infectious disorder

FLNB ABO ITPR2

7.32e-0626433MONDO_0043424
Diseasemultiple inositol polyphosphate phosphatase 1 measurement

MINPP1 ABO

1.24e-054432EFO_0801811
Diseasecadherin-5 measurement

ABO GBGT1

2.07e-055432EFO_0008060
DiseaseEczema

POLI CARD11 ABO LCLAT1 ITPR3

8.60e-05310435HP_0000964
Diseaseprotein FAM3D measurement

ABO GBGT1

1.36e-0412432EFO_0021869
DiseaseSjogren's Syndrome

IRAK1BP1 GTF2I

1.60e-0413432C1527336
DiseaseSicca Syndrome

IRAK1BP1 GTF2I

1.60e-0413432C0086981
Diseasetyrosine-protein kinase receptor Tie-1, soluble measurement

ABO GBGT1

1.60e-0413432EFO_0008312
Diseaseobesity (implicated_via_orthology)

THADA ITPR1 ITPR2 ITPR3

2.71e-04215434DOID:9970 (implicated_via_orthology)
Diseasea disintegrin and metalloproteinase with thrombospondin motifs 13 measurement

ABO GBGT1

2.78e-0417432EFO_0008011
Diseasetissue factor measurement

IRAK1BP1 ABO

4.28e-0421432EFO_0010623
Diseasegastric ulcer

ABO PLCL2

4.28e-0421432EFO_0009454
Diseasee-selectin measurement

ABO GBGT1

4.70e-0422432EFO_0004575
Diseasebreast cancer, COVID-19

ABO GBGT1

4.70e-0422432MONDO_0007254, MONDO_0100096
Diseasecardiovascular disease

IRAK1BP1 THADA GTF2I ODAD2 RUVBL1

5.17e-04457435EFO_0000319
Diseaseresistin measurement

THADA LHX8

8.21e-0429432EFO_0004819
Diseaselifestyle measurement, anxiety disorder measurement

CCDC178 CFAP54 GBGT1

1.05e-03137433EFO_0007795, EFO_0010724
Diseasepeptic ulcer disease

ABO PLCL2

1.06e-0333432MONDO_0004247
Diseasediverticulitis

ABO LHX8

1.34e-0337432EFO_1001460

Protein segments in the cluster

PeptideGeneStartEntry
HYMEEAEAVCDRVAI

ABCA5

1491

Q8WWZ7
HEDAECEKLMELYER

ABCF2

181

Q9UG63
NEVIHCYKMEDIDIV

CFAP54

651

Q96N23
YLVCVDVDMEFRDHV

ABO

206

P16442
DDEAIESHDICYKMN

ADAM7

516

Q9H2U9
DMACHKIPVEADFLY

CASP3

181

P42574
EDDHDVVSYEIKDMC

CFAP44

656

Q96MT7
IECDVVKDYAFVHME

RBM14

106

Q96PK6
ECDIVKDYAFVHMER

RBM4

106

Q9BWF3
KDYAFVHMERAEDAV

RBM4

111

Q9BWF3
FVNHCYVDTEVEMKE

ITPR2

1426

Q14571
FVNHCYVDTEVEMKE

ITPR3

1416

Q14573
RHFIDEEMDIKDFCT

OTUB2

151

Q96DC9
AYHMEAEVCITFTEF

IRAK1BP1

121

Q5VVH5
LNHCYVDTEVEMKEI

ITPR1

1436

Q14643
VKFADHVVCEEECKY

KCNT1

481

Q5JUK3
HVVCEEECKYAMLAL

KCNT1

486

Q5JUK3
KDDKSHFEDMIDYFC

LCLAT1

176

Q6UWP7
DHYMQEKKDCEERIF

CCDC178

711

Q5BJE1
YAVHIMCDDEDIKDS

FLNB

616

O75369
YCEHMAIVKLATEDI

OR52A5

181

Q9H2C5
PDYCHDKMIICSEEE

KNL1

771

Q8NG31
EEKVLCRVHYDCMLD

LHX8

181

Q68G74
HAVCEREAIAVFMEY

GBP7

356

Q8N8V2
ADHVVCEEEFKYAML

KCNT2

431

Q6UVM3
ECDIVKDYAFVHMER

RBM4B

106

Q9BQ04
KDYAFVHMERAEDAV

RBM4B

111

Q9BQ04
TFVDVMEFKDHVCEL

NCKAP1

96

Q9Y2A7
IEECDLEMYFSVDKE

ITCH

696

Q96J02
HREVDYLFCLDVDMV

GBGT1

196

Q8N5D6
EMVTCKSEFYHDEFK

GAN

486

Q9H2C0
FDAHYMAVDVDECKE

MASP1

131

P48740
FVKYCVEEEEKAAEM

GTF2I

76

P78347
VHVDLDCFYAQVEMI

POLI

56

Q9UNA4
KCDDVVHVRDTMYQD

CARD11

796

Q9BXL7
IVDESNVKYFLHMCE

FAM83G

206

A6ND36
DKDLEYVHTFMNVCF

DROSHA

1231

Q9NRR4
CVESMHQVEEDYLFE

THADA

1816

Q6YHU6
DYHDCMNVVEVFLEK

SYNE1

4241

Q8NF91
FREIEVEVYMAACHS

SLC26A6

696

Q9BXS9
EHCAMAIYQCAEDKE

ODAD2

691

Q5T2S8
VYEKIVHCQKAAMEF

PLCL2

1021

Q9UPR0
EQCVEKYFHEKMEDV

TRPM6

1151

Q9BX84
MRFFDHCEKFLTEVE

MINPP1

226

Q9UNW1
LEHEDEKVNMYCVTD

MID1

176

O15344
VDEVHMLDIECFTYL

RUVBL1

301

Q9Y265
EHGEKIYFFCEDDEM

TRIM10

101

Q9UDY6
IHYIDDILCAAEMKD

ERVK-19

196

Q9WJR5
HDFEEQCVEMYFNEK

TRPM7

1171

Q96QT4