Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontranscription coactivator activity

ARID1B FUS TCF20 NKX2-1 HCFC1

1.74e-04303355GO:0003713
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

GATA4 SP1 TARDBP HOXD3 NKX2-1 HCFC1 NFIX NR2F1 SP7

2.21e-041244359GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

GATA4 SP1 TARDBP HOXD3 NKX2-1 HCFC1 NFIX NR2F1 SP7

2.60e-041271359GO:0000987
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

GATA4 SP1 HOXD3 NKX2-1 NFIX SP7

3.85e-04560356GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

GATA4 SP1 HOXD3 NKX2-1 NFIX SP7

4.07e-04566356GO:0001216
GeneOntologyMolecularFunctionmolecular adaptor activity

MAPK8IP1 SP1 TARDBP STRN3 ARID1B FUS TCF20 NKX2-1 HCFC1

4.21e-041356359GO:0060090
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

GATA4 SP1 TARDBP HOXD3 NKX2-1 HCFC1 NFIX NR2F1 SP7

7.18e-041459359GO:0000977
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

MAPK8IP1 TARDBP STRN3 ARID1B FUS TCF20 NKX2-1 HCFC1

7.29e-041160358GO:0030674
GeneOntologyMolecularFunctionchromatin binding

GATA4 ARID1B FUS TAF5 HCFC1 NFIX

1.63e-03739356GO:0003682
GeneOntologyMolecularFunctiontranscription coregulator binding

GATA4 SP1 NKX2-1

1.87e-03140353GO:0001221
GeneOntologyMolecularFunctionmolecular condensate scaffold activity

TARDBP FUS

2.46e-0342352GO:0140693
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

GATA4 SP1 HOXD3 NKX2-1 NFIX NR2F1 CREBZF SP7

2.58e-031412358GO:0000981
GeneOntologyMolecularFunctiontranscription coregulator activity

ARID1B FUS TCF20 NKX2-1 HCFC1

2.80e-03562355GO:0003712
GeneOntologyMolecularFunctionDNA-binding transcription factor binding

GATA4 SP1 FUS NKX2-1 HCFC1

3.26e-03582355GO:0140297
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

GATA4 SP1 STRN3 TAF5 TCF20 HOXD3 NKX2-1 HCFC1 NFIX NR2F1 CREBZF SP7

1.63e-0613903512GO:0045944
GeneOntologyBiologicalProcessresponse to zinc ion starvation

SP1 SP7

1.00e-049352GO:0120127
GeneOntologyBiologicalProcesscellular response to zinc ion starvation

SP1 SP7

1.00e-049352GO:0034224
GeneOntologyBiologicalProcesspositive regulation of gene expression

GATA4 SP1 TARDBP C14orf93 ARID1B FUS HOXD3 NKX2-1 HNRNPAB HCFC1

1.01e-0414463510GO:0010628
GeneOntologyCellularComponentchromatin

GATA4 SP1 TARDBP TNKS1BP1 ARID1B TAF5 HOXD3 NKX2-1 HNRNPAB HCFC1 NFIX CREBZF SP7

3.60e-0714803513GO:0000785
GeneOntologyCellularComponenttranscription regulator complex

GATA4 SP1 TAF5 NKX2-1 HNRNPAB CREBZF

4.20e-04596356GO:0005667
MousePhenoslow extinction of fear memory

ARID1B NR2F1

1.62e-053332MP:0012318
MousePhenoincreased neocortex size

NFIX NR2F1

8.06e-056332MP:0020067
MousePhenoabnormal cerebral cortex morphology

TARDBP ARID1B TCF20 HCFC1 NFIX NR2F1

1.03e-04328336MP:0000788
MousePhenocognitive inflexibility

TARDBP ARID1B

1.50e-048332MP:0014115
MousePhenoabnormal response to social novelty

ARID1B TCF20 NFIX

2.05e-0449333MP:0020395
MousePhenoabnormal cingulate gyrus morphology

NFIX NR2F1

2.40e-0410332MP:0004167
DomainSp1_fam

SP1 SP7

1.61e-0410362IPR030450
DomainRRM_1

CSTF2 TARDBP FUS HNRNPAB

6.66e-04208364PF00076
DomainRRM

CSTF2 TARDBP FUS HNRNPAB

7.80e-04217364SM00360
DomainRRM_dom

CSTF2 TARDBP FUS HNRNPAB

9.23e-04227364IPR000504
DomainRRM

CSTF2 TARDBP FUS HNRNPAB

9.69e-04230364PS50102
Domain-

CSTF2 TARDBP FUS HNRNPAB

1.21e-032443643.30.70.330
DomainNucleotide-bd_a/b_plait

CSTF2 TARDBP FUS HNRNPAB

1.48e-03258364IPR012677
Domain-

GATA4 NR2F1

5.39e-03573623.30.50.10
DomainZnf_NHR/GATA

GATA4 NR2F1

5.58e-0358362IPR013088
DomainCa/CaM-dep_Ca-dep_prot_Kinase

SNRK PSKH2

7.81e-0369362IPR020636
PathwayWP_ADIPOGENESIS

GATA4 SP1 IRS4 NR2F1

1.23e-04131284M39505
PathwayWP_ADIPOGENESIS_GENES

GATA4 SP1 IRS4 NR2F1

1.46e-04137284MM15970
PathwayWP_MECP2_AND_ASSOCIATED_RETT_SYNDROME

SP1 TARDBP FUS

3.98e-0473283M39401
PathwayWP_MITOCHONDRIAL_GENE_EXPRESSION

SP1 HCFC1

6.37e-0419282M39544
PathwayWP_MITOCHONDRIAL_GENE_EXPRESSION

SP1 HCFC1

6.37e-0419282MM15973
Pubmed

Human transcription factor protein interaction networks.

GATA4 CSTF2 SP1 TARDBP ARID1B IRS4 FBN2 HRNR TAF5 TCF20 HCFC1 NFIX SP7

8.61e-101429361335140242
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

GATA4 SP1 TARDBP TAF5 TCF20 HOXD3 NKX2-1 HNRNPAB HCFC1 SP7

1.39e-08877361020211142
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

CSTF2 SP1 TARDBP C14orf93 FUS TAF5 TCF20 HNRNPAB HCFC1 NFIX NR2F1

4.63e-081294361130804502
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

CSTF2 TARDBP TNKS1BP1 ARID1B IRS4 TAF5 TCF20 HCFC1

7.52e-0854936838280479
Pubmed

ATG5 is required for B cell polarization and presentation of particulate antigens.

CSTF2 SP1 TARDBP FUS TAF5 HNRNPAB HCFC1 GLG1

4.81e-0770136830196744
Pubmed

High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.

TARDBP TNKS1BP1 FUS TCF20 UBE2Q1 DMKN HNRNPAB NFIX NR2F1

7.21e-07102136926760575
Pubmed

The transcriptional activity of osterix requires the recruitment of Sp1 to the osteocalcin proximal promoter.

SP1 SP7

1.04e-06236221820092
Pubmed

FUS/TLS forms cytoplasmic aggregates, inhibits cell growth and interacts with TDP-43 in a yeast model of amyotrophic lateral sclerosis.

TARDBP FUS

1.04e-06236221452073
Pubmed

Lost in local translation: TDP-43 and FUS in axonal/neuromuscular junction maintenance and dysregulation in amyotrophic lateral sclerosis.

TARDBP FUS

1.04e-06236236963381
Pubmed

FUS and TDP43 genetic variability in FTD and CBS.

TARDBP FUS

1.04e-06236221943958
Pubmed

Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models.

TARDBP FUS

1.04e-06236223104007
Pubmed

Identification of novel FUS and TARDBP gene mutations in Chinese amyotrophic lateral sclerosis patients with HRM analysis.

TARDBP FUS

1.04e-06236233159016
Pubmed

Characteristic Features of FUS Inclusions in Spinal Motor Neurons of Sporadic Amyotrophic Lateral Sclerosis.

TARDBP FUS

1.04e-06236232142134
Pubmed

The ALS-associated proteins FUS and TDP-43 function together to affect Drosophila locomotion and life span.

TARDBP FUS

1.04e-06236221881207
Pubmed

Sustained expression of TDP-43 and FUS in motor neurons in rodent's lifetime.

TARDBP FUS

1.04e-06236220616880
Pubmed

Trends in Understanding the Pathological Roles of TDP-43 and FUS Proteins.

TARDBP FUS

1.04e-06236233433879
Pubmed

Different recognition modes of G-quadruplex RNA between two ALS/FTLD-linked proteins TDP-43 and FUS.

TARDBP FUS

1.04e-06236233269497
Pubmed

A Drosophila model of FUS-related neurodegeneration reveals genetic interaction between FUS and TDP-43.

TARDBP FUS

1.04e-06236221487023
Pubmed

ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS.

TARDBP FUS

1.04e-06236220624952
Pubmed

Human TDP-43 and FUS selectively affect motor neuron maturation and survival in a murine cell model of ALS by non-cell-autonomous mechanisms.

TARDBP FUS

1.04e-06236226174443
Pubmed

Stress granules in neurodegeneration--lessons learnt from TAR DNA binding protein of 43 kDa and fused in sarcoma.

TARDBP FUS

1.04e-06236223587065
Pubmed

Physiological functions and pathobiology of TDP-43 and FUS/TLS proteins.

TARDBP FUS

1.04e-06236227015757
Pubmed

Requirements for stress granule recruitment of fused in sarcoma (FUS) and TAR DNA-binding protein of 43 kDa (TDP-43).

TARDBP FUS

1.04e-06236222563080
Pubmed

How do the RNA-binding proteins TDP-43 and FUS relate to amyotrophic lateral sclerosis and frontotemporal degeneration, and to each other?

TARDBP FUS

1.04e-06236223041957
Pubmed

TARDBP and FUS mutations associated with amyotrophic lateral sclerosis: summary and update.

TARDBP FUS

1.04e-06236223559573
Pubmed

K(v)1.5 potassium channel gene regulation by Sp1 transcription factor and oxidative stress.

SP1 KCNA5

1.04e-06236217660393
Pubmed

RNA and the RNA-binding protein FUS act in concert to prevent TDP-43 spatial segregation.

TARDBP FUS

1.04e-06236238311174
Pubmed

Mutant TDP-43 and FUS cause age-dependent paralysis and neurodegeneration in C. elegans.

TARDBP FUS

1.04e-06236222363618
Pubmed

SARS-CoV-2 impairs the disassembly of stress granules and promotes ALS-associated amyloid aggregation.

TARDBP FUS

1.04e-06236235384603
Pubmed

From transcriptomic to protein level changes in TDP-43 and FUS loss-of-function cell models.

TARDBP FUS

1.04e-06236226514432
Pubmed

TDP-43 and FUS RNA-binding proteins bind distinct sets of cytoplasmic messenger RNAs and differently regulate their post-transcriptional fate in motoneuron-like cells.

TARDBP FUS

1.04e-06236222427648
Pubmed

TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia.

TARDBP FUS

1.04e-06236220864052
Pubmed

Molecular determinants and genetic modifiers of aggregation and toxicity for the ALS disease protein FUS/TLS.

TARDBP FUS

1.04e-06236221541367
Pubmed

Reduction of polyglutamine toxicity by TDP-43, FUS and progranulin in Huntington's disease models.

TARDBP FUS

1.04e-06236223172908
Pubmed

RNA Binding Proteins and the Pathogenesis of Frontotemporal Lobar Degeneration.

TARDBP FUS

1.04e-06236230355151
Pubmed

Rethinking ALS: the FUS about TDP-43.

TARDBP FUS

1.04e-06236219303844
Pubmed

Conjoint pathologic cascades mediated by ALS/FTLD-U linked RNA-binding proteins TDP-43 and FUS.

TARDBP FUS

1.04e-06236221956718
Pubmed

TDP-43/FUS in motor neuron disease: Complexity and challenges.

TARDBP FUS

1.04e-06236227693252
Pubmed

Changes to the TDP-43 and FUS Interactomes Induced by DNA Damage.

TARDBP FUS

1.04e-06236231693373
Pubmed

Cytoplasmic functions of TDP-43 and FUS and their role in ALS.

TARDBP FUS

1.04e-06236231132467
Pubmed

Reversible induction of TDP-43 granules in cortical neurons after traumatic injury.

TARDBP FUS

1.04e-06236228941811
Pubmed

Two familial ALS proteins function in prevention/repair of transcription-associated DNA damage.

TARDBP FUS

1.04e-06236227849576
Pubmed

"STRESSED OUT": The role of FUS and TDP-43 in amyotrophic lateral sclerosis.

TARDBP FUS

1.04e-06236232758633
Pubmed

Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs.

TARDBP FUS

1.04e-06236223023293
Pubmed

Rapid in vitro quantification of TDP-43 and FUS mislocalisation for screening of gene variants implicated in frontotemporal dementia and amyotrophic lateral sclerosis.

TARDBP FUS

1.04e-06236234290285
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

TARDBP IRS4 HRNR TAF5 HCFC1 NFIX NR2F1

1.96e-0658336729844126
Pubmed

Morphogenetic lung defects of JSAP1-deficient embryos proceeds via the disruptions of the normal expressions of cytoskeletal and chaperone proteins.

MAPK8IP1 NKX2-1 NFIX

2.31e-062536318324732
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

TARDBP ARID1B TCF20 HNRNPAB HCFC1

3.11e-0622036535785414
Pubmed

Aberrant localization of FUS and TDP43 is associated with misfolding of SOD1 in amyotrophic lateral sclerosis.

TARDBP FUS

3.12e-06336222493728
Pubmed

TDP-43 or FUS-induced misfolded human wild-type SOD1 can propagate intercellularly in a prion-like fashion.

TARDBP FUS

3.12e-06336226926802
Pubmed

Cdc48/VCP and Endocytosis Regulate TDP-43 and FUS Toxicity and Turnover.

TARDBP FUS

3.12e-06336231767634
Pubmed

Hu antigen R (HuR) is a positive regulator of the RNA-binding proteins TDP-43 and FUS/TLS: implications for amyotrophic lateral sclerosis.

TARDBP FUS

3.12e-06336225239623
Pubmed

Potentiating Hsp104 activity via phosphomimetic mutations in the middle domain.

TARDBP FUS

3.12e-06336229788207
Pubmed

No effect on SOD1 splicing by TARDP or FUS mutations.

TARDBP FUS

3.12e-06336221403029
Pubmed

Caudate atrophy on MRI is a characteristic feature of FTLD-FUS.

TARDBP FUS

3.12e-06336220236174
Pubmed

Overexpression of a conserved HSP40 chaperone reduces toxicity of several neurodegenerative disease proteins.

TARDBP FUS

3.12e-06336229308690
Pubmed

Neuronal cytoplasmic inclusions in tau, TDP-43, and FUS molecular subtypes of frontotemporal lobar degeneration share similar spatial patterns.

TARDBP FUS

3.12e-06336228984110
Pubmed

GATA-4 and GATA-6 modulate tissue-specific transcription of the human gene for P450c17 by direct interaction with Sp1.

GATA4 SP1

3.12e-06336214988427
Pubmed

Mice Carrying ALS Mutant TDP-43, but Not Mutant FUS, Display In Vivo Defects in Axonal Transport of Signaling Endosomes.

TARDBP FUS

3.12e-06336232187538
Pubmed

Distinct partitioning of ALS associated TDP-43, FUS and SOD1 mutants into cellular inclusions.

TARDBP FUS

3.12e-06336226293199
Pubmed

Heterogeneous sphingosine-1-phosphate lyase gene expression and its regulatory mechanism in human lung cancer cell lines.

GATA4 SP1

3.12e-06336221184844
Pubmed

Induction of fibrillin-2 and periostin expression in Osterix-knockdown MC3T3-E1 cells.

FBN2 SP7

3.12e-06336227751812
Pubmed

Roles of ataxin-2 in pathological cascades mediated by TAR DNA-binding protein 43 (TDP-43) and Fused in Sarcoma (FUS).

TARDBP FUS

3.12e-06336223048034
Pubmed

Osterix induces Col1a1 gene expression through binding to Sp1 sites in the bone enhancer and proximal promoter regions.

SP1 SP7

3.12e-06336223159876
Pubmed

Screening of SOD1, FUS and TARDBP genes in patients with amyotrophic lateral sclerosis in central-southern China.

TARDBP FUS

3.12e-06336227604643
Pubmed

Zhangfei is a potent and specific inhibitor of the host cell factor-binding transcription factor Luman.

HCFC1 CREBZF

3.12e-06336215705566
Pubmed

A novel missense mutation of CMT2P alters transcription machinery.

TARDBP FUS

3.12e-06336227615052
Pubmed

NMJ-Analyser identifies subtle early changes in mouse models of neuromuscular disease.

TARDBP FUS

3.12e-06336234112844
Pubmed

Oxr1 improves pathogenic cellular features of ALS-associated FUS and TDP-43 mutations.

TARDBP FUS

3.12e-06336225792726
Pubmed

Gata4 and Sp1 regulate expression of the erythropoietin receptor in cardiomyocytes.

GATA4 SP1

3.12e-06336221029371
Pubmed

Zhangfei: a second cellular protein interacts with herpes simplex virus accessory factor HCF in a manner similar to Luman and VP16.

HCFC1 CREBZF

3.12e-06336210871379
Pubmed

Axonal transport defects are a common phenotype in Drosophila models of ALS.

TARDBP FUS

3.12e-06336227056981
Pubmed

Regulatory Role of RNA Chaperone TDP-43 for RNA Misfolding and Repeat-Associated Translation in SCA31.

TARDBP FUS

3.12e-06336228343865
Pubmed

COUP-TF and Sp1 interact and cooperate in the transcriptional activation of the human immunodeficiency virus type 1 long terminal repeat in human microglial cells.

SP1 NR2F1

3.12e-0633629388268
Pubmed

Connecting RNA-Modifying Similarities of TDP-43, FUS, and SOD1 with MicroRNA Dysregulation Amidst A Renewed Network Perspective of Amyotrophic Lateral Sclerosis Proteinopathy.

TARDBP FUS

3.12e-06336232422969
Pubmed

A census of human transcription factors: function, expression and evolution.

GATA4 SP1 HOXD3 NKX2-1 NFIX NR2F1 CREBZF SP7

3.31e-0690836819274049
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

CSTF2 TARDBP ARID1B IRS4 FUS TCF20 HNRNPAB HCFC1

4.76e-0695436836373674
Pubmed

Endogenous purification reveals GREB1 as a key estrogen receptor regulatory factor.

TARDBP TNKS1BP1 FUS KRT77

5.74e-0611336423403292
Pubmed

Control of Fiat (factor inhibiting ATF4-mediated transcription) expression by Sp family transcription factors in osteoblasts.

SP1 SP7

6.24e-06436223463631
Pubmed

A novel protein, Luman/CREB3 recruitment factor, inhibits Luman activation of the unfolded protein response.

HCFC1 CREBZF

6.24e-06436218391022
Pubmed

8-oxoguanine DNA glycosylase-1 augments proinflammatory gene expression by facilitating the recruitment of site-specific transcription factors.

SP1 TAF5

6.24e-06436224489103
Pubmed

Potentiated Hsp104 variants suppress toxicity of diverse neurodegenerative disease-linked proteins.

TARDBP FUS

6.24e-06436225062688
Pubmed

Interaction of HCF-1 with a cellular nuclear export factor.

HCFC1 CREBZF

6.24e-06436212235138
Pubmed

Site-specific proteolysis of the transcriptional coactivator HCF-1 can regulate its interaction with protein cofactors.

SP1 HCFC1

6.24e-06436216624878
Pubmed

Post-translational modification sites are present in hydrophilic cavities of alpha-synuclein, tau, FUS, and TDP-43 fibrils: A molecular dynamics study.

TARDBP FUS

6.24e-06436238458997
Pubmed

Rab1-dependent ER-Golgi transport dysfunction is a common pathogenic mechanism in SOD1, TDP-43 and FUS-associated ALS.

TARDBP FUS

6.24e-06436226298469
Pubmed

SOD1, ANG, TARDBP and FUS mutations in amyotrophic lateral sclerosis: a United States clinical testing lab experience.

TARDBP FUS

6.24e-06436222292843
Pubmed

Shared Molecular Mechanisms in Alzheimer's Disease and Amyotrophic Lateral Sclerosis: Neurofilament-Dependent Transport of sAPP, FUS, TDP-43 and SOD1, with Endoplasmic Reticulum-Like Tubules.

TARDBP FUS

6.24e-06436226605911
Pubmed

Regulation of renin enhancer activity by nuclear factor I and Sp1/Sp3.

SP1 NFIX

6.24e-06436212591615
Pubmed

Generation and analysis of innovative genomically humanized knockin SOD1, TARDBP (TDP-43), and FUS mouse models.

TARDBP FUS

6.24e-06436234988393
Pubmed

Mutation analysis of SOD1, C9orf72, TARDBP and FUS genes in ethnically-diverse Malaysian patients with amyotrophic lateral sclerosis (ALS).

TARDBP FUS

6.24e-06436234404558
Pubmed

Co-aggregation of RNA binding proteins in ALS spinal motor neurons: evidence of a common pathogenic mechanism.

TARDBP FUS

6.24e-06436222941224
Pubmed

Nicotine induces the up-regulation of the α7-nicotinic receptor (α7-nAChR) in human squamous cell lung cancer cells via the Sp1/GATA protein pathway.

GATA4 SP1

6.24e-06436224089524
Pubmed

Amyotrophic lateral sclerosis-associated proteins TDP-43 and FUS/TLS function in a common biochemical complex to co-regulate HDAC6 mRNA.

TARDBP FUS

6.24e-06436220720006
Pubmed

RNA-binding proteins in neurological development and disease.

TARDBP FUS

6.24e-06436232865115
Pubmed

Cytoplasmic mislocalization of RNA splicing factors and aberrant neuronal gene splicing in TDP-43 transgenic pig brain.

TARDBP FUS

6.24e-06436226334913
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

CSTF2 TARDBP IRS4 FUS HRNR TCF20 HNRNPAB KRT77

7.99e-06102436824711643
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

STRN3 ARID1B KCNA5 TAF5 UBE2Q1 HNRNPAB HCFC1

8.57e-0673036734857952
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

TARDBP IRS4 FUS TCF20 HNRNPAB

9.03e-0627436534244482
Pubmed

Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses.

TARDBP FUS

1.04e-05536227378374
InteractionCPSF1 interactions

CSTF2 TARDBP ARID1B FUS TAF5 TCF20 SP7

2.92e-07255367int:CPSF1
InteractionTBL1XR1 interactions

GATA4 SP1 IRS4 RAB2A NKX2-1 SP7

1.06e-06192366int:TBL1XR1
InteractionTAF15 interactions

GATA4 TARDBP FUS TAF5 NKX2-1 HNRNPAB HCFC1

6.66e-06408367int:TAF15
InteractionWWTR1 interactions

CSTF2 TNKS1BP1 ARID1B IRS4 TCF20 NKX2-1 HCFC1

8.30e-06422367int:WWTR1
InteractionPOU2F1 interactions

SP1 HCFC1 NFIX NR2F1 SP7

1.41e-05175365int:POU2F1
InteractionMYCN interactions

SP1 TARDBP ARID1B IRS4 FUS HRNR TCF20 HNRNPAB HCFC1 KRT77 SP7

1.73e-0513733611int:MYCN
InteractionSS18 interactions

GATA4 ARID1B FUS SP7

1.80e-0588364int:SS18
InteractionCIC interactions

TARDBP IRS4 HRNR TAF5 HCFC1 NFIX NR2F1 SP7

1.96e-05673368int:CIC
InteractionSOX17 interactions

ARID1B HRNR TCF20 NFIX

2.43e-0595364int:SOX17
InteractionGATA6 interactions

GATA4 SP1 NKX2-1

3.02e-0534363int:GATA6
InteractionSMARCD1 interactions

GATA4 ARID1B FUS HOXD3 NFIX SP7

3.25e-05349366int:SMARCD1
InteractionSMARCC2 interactions

GATA4 SP1 ARID1B FUS NFIX SP7

3.46e-05353366int:SMARCC2
InteractionSMARCD3 interactions

GATA4 ARID1B NFIX SP7

3.88e-05107364int:SMARCD3
InteractionNCOR1 interactions

GATA4 SP1 RAB2A HCFC1 NFIX SP7

4.04e-05363366int:NCOR1
InteractionTLE3 interactions

CSTF2 TNKS1BP1 ARID1B TCF20 NFIX SP7

4.92e-05376366int:TLE3
InteractionHSP90AA1 interactions

GATA4 SP1 TARDBP IRS4 FUS HRNR KCNA5 PSKH2 HNRNPAB HCFC1

5.11e-0512633610int:HSP90AA1
InteractionSMARCC1 interactions

GATA4 SP1 ARID1B FUS NFIX SP7

5.53e-05384366int:SMARCC1
InteractionSMAD2 interactions

GATA4 SP1 ARID1B FBN2 TAF5 HCFC1

5.61e-05385366int:SMAD2
InteractionARHGEF28 interactions

MAPK8IP1 TARDBP FUS

5.73e-0542363int:ARHGEF28
InteractionMECP2 interactions

CSTF2 SP1 TARDBP TNKS1BP1 ARID1B FUS HRNR TCF20 NKX2-1 HNRNPAB

5.99e-0512873610int:MECP2
InteractionBCL7A interactions

GATA4 ARID1B NFIX SP7

6.69e-05123364int:BCL7A
InteractionCUL2 interactions

GATA4 TARDBP ARID1B IRS4 FUS HRNR HNRNPAB

7.17e-05591367int:CUL2
InteractionGATA4 interactions

GATA4 SP1 TARDBP IRS4 FUS HNRNPAB

8.05e-05411366int:GATA4
InteractionPAX9 interactions

GATA4 ARID1B TCF20 NFIX

8.30e-05130364int:PAX9
InteractionGABPA interactions

SP1 HCFC1 NFIX SP7

8.30e-05130364int:GABPA
InteractionMDC1 interactions

GATA4 ARID1B FUS TCF20 NKX2-1 HNRNPAB

8.38e-05414366int:MDC1
InteractionYPEL1 interactions

STRN3 FUS

8.63e-058362int:YPEL1
InteractionGLUD1 interactions

SP1 FUS NKX2-1 PSKH2 SP7

9.01e-05258365int:GLUD1
InteractionYAP1 interactions

TARDBP TNKS1BP1 ARID1B IRS4 FUS HRNR TAF5 TCF20 HCFC1

9.92e-051095369int:YAP1
InteractionNCOR2 interactions

GATA4 SP1 NFIX NR2F1 SP7

1.00e-04264365int:NCOR2
InteractionCIBAR1 interactions

FUS HRNR HCFC1 KRT77

1.02e-04137364int:CIBAR1
InteractionPHF10 interactions

GATA4 ARID1B FUS SP7

1.08e-04139364int:PHF10
InteractionSNRPC interactions

GATA4 CSTF2 TARDBP FUS HNRNPAB HCFC1

1.17e-04440366int:SNRPC
InteractionARID1A interactions

GATA4 ARID1B FUS NFIX SP7

1.24e-04276365int:ARID1A
InteractionRNF4 interactions

SP1 TARDBP ARID1B FUS FBN2 TCF20 RAB2A HNRNPAB HCFC1 GLG1

1.30e-0414123610int:RNF4
InteractionSMARCA4 interactions

GATA4 SP1 ARID1B FUS NKX2-1 SP7

1.53e-04462366int:SMARCA4
InteractionARID2 interactions

ARID1B FUS NFIX SP7

1.56e-04153364int:ARID2
InteractionJUN interactions

MAPK8IP1 SP1 SNRK TCF20 HCFC1 NFIX

1.68e-04470366int:JUN
InteractionTAF4 interactions

SP1 TAF5 HCFC1 NFIX

1.68e-04156364int:TAF4
InteractionFLI1 interactions

ARID1B FUS SP7

1.84e-0462363int:FLI1
InteractionKDM6A interactions

GATA4 HCFC1 NFIX SP7

1.94e-04162364int:KDM6A
InteractionSP7 interactions

ARID1B FBN2 TCF20 NFIX SP7

1.94e-04304365int:SP7
InteractionTOP1 interactions

GATA4 CSTF2 TARDBP TCF20 NKX2-1 HNRNPAB HCFC1

1.98e-04696367int:TOP1
InteractionFBN2 interactions

SP1 FBN2 SP7

2.12e-0465363int:FBN2
InteractionBICRA interactions

ARID1B NFIX SP7

2.32e-0467363int:BICRA
InteractionESRRA interactions

SP1 FUS CREBZF

2.32e-0467363int:ESRRA
InteractionGLDC interactions

TARDBP IRS4 FUS TCF20 HNRNPAB

2.50e-04321365int:GLDC
InteractionSQSTM1 interactions

GATA4 TARDBP TNKS1BP1 FUS RAB2A HNRNPAB GLG1 NFIX NYNRIN

2.82e-041257369int:SQSTM1
InteractionAR interactions

SP1 TARDBP ARID1B HRNR TCF20 HNRNPAB HCFC1 NFIX

2.96e-04992368int:AR
InteractionSMARCD2 interactions

GATA4 ARID1B NFIX SP7

3.09e-04183364int:SMARCD2
InteractionSMC5 interactions

CSTF2 TARDBP ARID1B IRS4 FUS TCF20 HNRNPAB HCFC1

3.12e-041000368int:SMC5
InteractionEP400 interactions

GATA4 HCFC1 NFIX SP7

3.15e-04184364int:EP400
InteractionSRRT interactions

GATA4 SP1 TARDBP FUS SP7

3.26e-04340365int:SRRT
InteractionDPF2 interactions

GATA4 ARID1B HNRNPAB NFIX SP7

3.67e-04349365int:DPF2
InteractionHNRNPA0 interactions

GATA4 TARDBP FUS RAB2A HNRNPAB

3.67e-04349365int:HNRNPA0
InteractionBAP1 interactions

CSTF2 SP1 TARDBP STRN3 IRS4 FUS HNRNPAB HCFC1 NFIX

3.91e-041314369int:BAP1
InteractionIRF2BP1 interactions

NKX2-1 NFIX SP7

4.06e-0481363int:IRF2BP1
InteractionSFPQ interactions

GATA4 SP1 TARDBP FUS NKX2-1 HNRNPAB

4.42e-04563366int:SFPQ
InteractionSMARCB1 interactions

GATA4 ARID1B FUS HCFC1 SP7

4.45e-04364365int:SMARCB1
InteractionSP1 interactions

GATA4 SP1 FBN2 HCFC1 NR2F1

4.50e-04365365int:SP1
InteractionFEV interactions

GATA4 ARID1B TAF5 TCF20

4.57e-04203364int:FEV
InteractionPAX2 interactions

MAPK8IP1 ARID1B NFIX

4.68e-0485363int:PAX2
InteractionSLX4 interactions

CSTF2 TARDBP IRS4 FUS TCF20 HCFC1

4.80e-04572366int:SLX4
InteractionRBBP4 interactions

SP1 FUS TCF20 NKX2-1 HCFC1 NR2F1

4.85e-04573366int:RBBP4
InteractionMEF2D interactions

SP1 FUS SP7

5.01e-0487363int:MEF2D
InteractionNFIC interactions

ARID1B NKX2-1 NFIX SP7

5.20e-04210364int:NFIC
InteractionPOU5F1 interactions

SP1 C14orf93 ARID1B TCF20 HNRNPAB HCFC1

5.36e-04584366int:POU5F1
InteractionSSBP1 interactions

GATA4 SP1 FUS NKX2-1 HNRNPAB NFIX

5.56e-04588366int:SSBP1
InteractionSOX10 interactions

SP1 ARID1B NFIX

5.89e-0492363int:SOX10
InteractionZNF608 interactions

HCFC1 NFIX SP7

6.08e-0493363int:ZNF608
InteractionHDAC1 interactions

GATA4 SP1 TNKS1BP1 IRS4 TCF20 NKX2-1 HCFC1 NFIX

6.20e-041108368int:HDAC1
InteractionCPSF4 interactions

GATA4 CSTF2 SP7

6.28e-0494363int:CPSF4
InteractionMSANTD2 interactions

NFIX SP7

6.38e-0421362int:MSANTD2
InteractionDPF1 interactions

ARID1B NFIX SP7

6.47e-0495363int:DPF1
InteractionRARA interactions

SP1 FUS NKX2-1 HNRNPAB

6.51e-04223364int:RARA
InteractionERG interactions

GATA4 ARID1B TCF20 HNRNPAB

6.51e-04223364int:ERG
InteractionNCOA3 interactions

ARID1B NKX2-1 NR2F1 SP7

6.62e-04224364int:NCOA3
InteractionSTUB1 interactions

SNRK IRS4 KCNA5 UBE2Q1 PSKH2 SP7

6.62e-04608366int:STUB1
InteractionNFIX interactions

ARID1B TAF5 NFIX SP7

6.96e-04227364int:NFIX
InteractionSS18L1 interactions

CSTF2 ARID1B SP7

7.09e-0498363int:SS18L1
InteractionHDAC2 interactions

GATA4 SP1 TNKS1BP1 FUS HRNR TCF20 HCFC1

7.35e-04865367int:HDAC2
InteractionCYLD interactions

TARDBP TNKS1BP1 FUS HRNR HNRNPAB GLG1 KRT77

7.50e-04868367int:CYLD
InteractionFKBP5 interactions

IRS4 COL6A6 PSKH2 HCFC1 NYNRIN

7.97e-04414365int:FKBP5
InteractionNACC1 interactions

TARDBP STRN3 SP7

8.19e-04103363int:NACC1
InteractionHMGA1 interactions

SP1 TCF20 NKX2-1 HNRNPAB HCFC1

8.41e-04419365int:HMGA1
InteractionBACC1 interactions

GATA4 HCFC1 NFIX

8.42e-04104363int:BACC1
InteractionCSTF1 interactions

CSTF2 TARDBP FUS

8.42e-04104363int:CSTF1
InteractionATG16L1 interactions

CSTF2 SP1 TARDBP FUS TAF5 HNRNPAB HCFC1 GLG1

8.43e-041161368int:ATG16L1
InteractionPPIA interactions

TARDBP STRN3 ARID1B FUS TCF20 HNRNPAB HCFC1

8.58e-04888367int:PPIA
InteractionSMAD1 interactions

GATA4 TAF5 TCF20 HCFC1

8.97e-04243364int:SMAD1
InteractionDDX3X interactions

SP1 TARDBP FUS HRNR GLG1 KRT77

9.46e-04651366int:DDX3X
InteractionEWSR1 interactions

GATA4 CSTF2 TARDBP FUS HRNR TCF20 HNRNPAB

9.65e-04906367int:EWSR1
InteractionIRF2BP2 interactions

NKX2-1 NFIX SP7

9.91e-04110363int:IRF2BP2
InteractionHEXIM1 interactions

CSTF2 ARID1B FUS HRNR HNRNPAB HCFC1 KRT77

1.01e-03913367int:HEXIM1
InteractionMAX interactions

CSTF2 FUS HCFC1 SP7

1.01e-03251364int:MAX
InteractionPTBP1 interactions

TARDBP FUS RAB2A NKX2-1 HNRNPAB

1.01e-03437365int:PTBP1
InteractionPCF11 interactions

CSTF2 FUS SP7

1.02e-03111363int:PCF11
InteractionPAX8 interactions

ARID1B NKX2-1 NFIX

1.02e-03111363int:PAX8
InteractionCRX interactions

GATA4 SP1 ARID1B TCF20

1.06e-03254364int:CRX
InteractionTBR1 interactions

ARID1B NFIX SP7

1.07e-03113363int:TBR1
Cytoband12q13.13

KRT77 SP7

1.28e-036736212q13.13
CytobandEnsembl 112 genes in cytogenetic band chr14q12

STRN3 NYNRIN

3.10e-03105362chr14q12
Cytoband1q21.3

HRNR UBE2Q1

3.83e-031173621q21.3
CytobandEnsembl 112 genes in cytogenetic band chr12q13

SP1 KRT77 SP7

4.43e-03423363chr12q13
CytobandEnsembl 112 genes in cytogenetic band chrXq22

CSTF2 IRS4

8.09e-03172362chrXq22
GeneFamilyZinc fingers C2H2-type|Sp transcription factors

SP1 SP7

5.54e-059232755
GeneFamilyRNA binding motif containing

CSTF2 TARDBP FUS HNRNPAB

1.39e-04213234725
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000

SP1 IRS4 FUS FBN2 KCNA5 GLG1 NFIX NR2F1

2.72e-05790348gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlasDevelopingGonad_e11.5_testes_emap-3226_top-relative-expression-ranked_1000

GATA4 MAPK8IP1 SP1 FUS HOXD3 HCFC1 NR2F1 NYNRIN

4.32e-05843348gudmap_developingGonad_e11.5_testes_1000
CoexpressionAtlasDevelopingGonad_e11.5_testes and mesonephros_emap-3226_top-relative-expression-ranked_1000

GATA4 MAPK8IP1 SP1 FUS HOXD3 HCFC1 NR2F1 NYNRIN

4.36e-05844348gudmap_developingGonad_e11.5_testes and mesonephros_1000
CoexpressionAtlasDevelopingGonad_e11.5_testes_emap-3226_top-relative-expression-ranked_500

GATA4 SP1 FUS HOXD3 HCFC1 NR2F1

6.06e-05437346gudmap_developingGonad_e11.5_testes_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_500

GATA4 FBN2 NYNRIN

7.86e-0552343gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k2_500
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_200

SP1 IRS4 FUS NFIX

1.39e-04166344gudmap_developingGonad_e18.5_epididymis_200
CoexpressionAtlasDevelopingGonad_e18.5_testes_emap-11164_top-relative-expression-ranked_1000

GATA4 SP1 IRS4 FUS HOXD3 HCFC1 NFIX

2.58e-04814347gudmap_developingGonad_e18.5_testes_1000
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Undetermined|Fibroblasts / Location, Cell class and cell subclass

SP1 STRN3 NKX2-1 HCFC1

1.50e-05186364403ac98f72a42721f84fbd7826f251a88ae534a2
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

GATA4 ARID1B FUS TCF20

1.50e-05186364de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

GATA4 ARID1B FUS TCF20

1.50e-051863640b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellParenchymal-10x5prime-Epithelial-Epi_alveolar-Dividing_AT2|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TNKS1BP1 NKX2-1 DMKN TAS1R3

1.74e-0519336444839a606ae2f8e37421bda46d588189e1c943d2
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Ngfr-Inhibitory_Neuron.Chat-Gad1Gad2-Slc17a8.Ngfr_(Globus_Pallidus/Nucleus_Basalis_(GP/NB),_cholinergic)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

LRRC66 HOXD3 XKR5

3.99e-05823631ed7d7f70f00d6e280cd59c54e710bb724c8b50b
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Ngfr-Inhibitory_Neuron.Chat-Gad1Gad2-Slc17a8.Ngfr_(Globus_Pallidus/Nucleus_Basalis_(GP/NB),_cholinergic)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

LRRC66 HOXD3 XKR5

3.99e-0582363a5d3c5b7012d8ca7418670242d22aad3ed8c5191
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Ngfr|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

LRRC66 HOXD3 XKR5

3.99e-0582363cefd8c6f60ef27fb8823faddca1cf8bbd636f474
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

ARID1B FUS CREBZF

2.25e-0414736394998bc40f5c08295cfe3bdcbe43f13b1e564b3d
ToppCell10x5'-Lung-Lymphocytic_B-ABC_aged-B_memory|Lung / Manually curated celltypes from each tissue

MAPK8IP1 DMKN TAS1R3

2.84e-04159363d3202ddc291b8686dbe67690df13c7daffec2199
ToppCell356C-Epithelial_cells-Epithelial-C_(AT2)-|356C / Donor, Lineage, Cell class and subclass (all cells)

NKX2-1 DMKN NFIX

2.94e-0416136378cb72c462167021195917a06052bcdc367ad890
ToppCell356C-Epithelial_cells-Epithelial-C_(AT2)|356C / Donor, Lineage, Cell class and subclass (all cells)

NKX2-1 DMKN NFIX

2.94e-0416136306e7becfd11d6ef1a45a9cfdfcb40b812600038e
ToppCell-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

GATA4 COL6A6 NR2F1

3.39e-041693638ebe9a88111c53a09c25a7b6a164a0a17880458d
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L6_LAMP5_ANKRD20A11P|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FBN2 KCNA5 SP7

3.39e-041693634034f307163bdeace58034f28b5f98ba4e040bca
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L6_LAMP5_C1QL2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FBN2 PSKH2 SP7

3.45e-0417036367619685a145fbd4a86d67f2c1c2ba3d5fe52fbe
ToppCell356C-Epithelial_cells-Epithelial-E_(AT2)-|356C / Donor, Lineage, Cell class and subclass (all cells)

NKX2-1 DMKN NFIX

3.45e-041703634cd3b7e43a061948084c01713ae141b5c2c07d89
ToppCell356C-Epithelial_cells-Epithelial-E_(AT2)|356C / Donor, Lineage, Cell class and subclass (all cells)

NKX2-1 DMKN NFIX

3.45e-0417036336c9f7f98612a72dc511c8da4358d67444f6bcf4
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GATA4 COL6A6 DMKN

3.63e-041733633725525b99a6011eda2ff5459b4fd2e1eab1f090
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GATA4 COL6A6 DMKN

3.63e-04173363ee7d1429f23f1b89a9a9f7bc07a84a44cf7acd1c
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA5 HOXD3 NR2F1

3.76e-04175363c1e082538f31b5c98ac63f71dcca4a1211a14708
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Endothelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA5 HOXD3 NR2F1

3.76e-04175363c36b4526970db9ccfbe2c70b00961fab9f13b133
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Endothelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA5 HOXD3 NR2F1

3.76e-041753632f9b5bdf8a62e8e99d1c4f677a8e5525bfd3b4ce
ToppCellfacs-Trachea-nan-18m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKX2-1 DMKN KRT77

3.76e-04175363eb87275da6f61ecb4fbc89421dfd27bead1e0f48
ToppCellfacs-Trachea-nan-18m-Epithelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKX2-1 DMKN KRT77

3.76e-041753633883675a726dd0c6c3a7113d59be2a093ea2dc6f
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NKX2-1 DMKN NYNRIN

3.88e-0417736375cb2067a3f2d1b5a964890b02b604d1e79bd163
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GATA4 COL6A6 DMKN

3.95e-04178363c413861148129be1ee94f2ceb5999840217eebe5
ToppCell3'_v3|World / Manually curated celltypes from each tissue

ARID1B FUS UBE2Q1

3.95e-0417836342502f14d9c756df8104900ac6484477b885d3d9
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L6_LAMP5_C1QL2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FBN2 PSKH2 SP7

3.95e-0417836339889db130216655a34796e7030ffeb372465500
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GATA4 COL6A6 DMKN

3.95e-04178363bcbdd45a2307f8aea14122fa0144b96b1f6eec48
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5|Hippocampus / BrainAtlas - Mouse McCarroll V32

TARDBP FUS HNRNPAB

4.08e-0418036344988c34861df359a68376500c42a64fbcc4b431
ToppCellE18.5-samps-Mesenchymal-Pericyte|E18.5-samps / Age Group, Lineage, Cell class and subclass

KCNA5 COL6A6 NR2F1

4.08e-041803630b1d370db64862fe1c7ea0ffaf06d03ec82e6e70
ToppCellAT2_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

NKX2-1 DMKN NFIX

4.15e-04181363ed0ea67f0607073aedf153f8d1073b35e46127c3
ToppCellBAL-Control-cDC_8|Control / Compartment, Disease Groups and Clusters

STRN3 TNKS1BP1 CREBZF

4.15e-04181363f370161afef2ec827a7b194c06abb9ac1a507cbb
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FBN2 NKX2-1 PSKH2

4.35e-04184363e2de27cee3ea80f9b7a9a7884ceceeaa67b3214a
ToppCelldroplet-Skin|droplet / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMKN NFIX KRT77

4.42e-04185363657fd191ed160f8620d57b33820ec7222806f289
ToppCellfacs-Heart-RV|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SNRK KCNA5 DMKN

4.42e-041853637cf2b0db059605032bfae60cf1b93c4c62608f0c
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

GATA4 COL6A6 DMKN

4.49e-041863638915436d09775f2828a7678af203b1082b36e21c
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FBN2 KCNA5 NFIX

4.49e-041863634d68ee3d32f7ef884faf402ef92b31b0eb4656f1
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FBN2 NKX2-1 PSKH2

4.63e-041883638268574584e5fb869a6cb8bbd7135cd7454a6a25
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FBN2 NKX2-1 PSKH2

4.70e-04189363222e67d3fd106c43b0cae6538dddeaa7be1f759f
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL6A6 NKX2-1 NFIX

4.70e-041893638e6b6025f5554672e26a5d19fe365acb4333789c
ToppCellAT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

NKX2-1 DMKN NFIX

4.70e-041893632d32f09efa982ae458568f6b1cd06bb5078d42a3
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FBN2 NKX2-1 PSKH2

4.78e-041903633b8d1e66ae68c1eee64095e75195d76d97e24026
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FBN2 NKX2-1 PSKH2

4.78e-0419036359720dfe9de1b980807644536c919d2a02ba69dd
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FBN2 NKX2-1 PSKH2

4.78e-04190363dc655e4782aab274f0c9b6e36a5ce315e3a1a4b9
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

GATA4 COL6A6 DMKN

4.78e-041903634f775ee24b14733f06ae40b45f2dc1a0f0df0705
ToppCellE15.5-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FBN2 NKX2-1 HNRNPAB

4.85e-041913636f5d91a9583bbb30dfaa30dd9c7772995a9196be
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

GATA4 COL6A6 DMKN

4.85e-04191363156b467187331ac6ca390d6ca861d9670bb7b956
ToppCelldroplet-Heart|droplet / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATA4 SNRK KCNA5

4.92e-0419236367a7e07a11091120edbccf739836235c422ec9c6
ToppCellE15.5-Epithelial-epithelial_progenitor_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FBN2 NKX2-1 HNRNPAB

4.92e-04192363cb6f42dcffe650f7958543531d8f5412b2f2eb12
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATA4 SNRK NYNRIN

4.92e-041923635890076929598e88fe9d59a4e4e858b446746ce9
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBN2 NFIX NR2F1

4.92e-04192363f053b89bfd6048c227667ff01c38df7c51d8a496
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GATA4 COL6A6 DMKN

5.00e-04193363cd45118ced91b10baed3b1068d4673ec99824b86
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GATA4 COL6A6 DMKN

5.00e-04193363adc9fc94f9ec686a417d08c0b8b7b7ab687afec0
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

COL6A6 DMKN NR2F1

5.08e-041943635f5f0cdeacd5e1b28717d78dabdb9eb95f661e36
ToppCellBL-critical-LOC-Epithelial-unknown_epithelial|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MAPK8IP1 DMKN NFIX

5.08e-041943636140ff8e776429c9593607da418b2d9c4f399d41
ToppCell356C-Epithelial_cells|356C / Donor, Lineage, Cell class and subclass (all cells)

NKX2-1 DMKN NFIX

5.15e-04195363d913d0a6c4797d9a873ddea6f340c3f152da1cf3
ToppCell(7)_Epithelial-A_(AT2)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

NKX2-1 DMKN NFIX

5.15e-04195363c9a6c65ee18d83bf34a4713d306a6e30db1325c2
ToppCell356C-Epithelial_cells-Epithelial-A_(AT2)-|356C / Donor, Lineage, Cell class and subclass (all cells)

NKX2-1 DMKN NFIX

5.23e-041963634715f19f844e7244fc4bc446cba7c8088c600fc3
ToppCell356C-Epithelial_cells-Epithelial-A_(AT2)|356C / Donor, Lineage, Cell class and subclass (all cells)

NKX2-1 DMKN NFIX

5.23e-0419636393a5d9b8bcff7d07596ef1f4f2b74f043835fc69
ToppCell3'-GW_trimst-2-LargeIntestine|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FUS COL6A6 NR2F1

5.23e-0419636327a216af92100224818c91e298428bee25ab0af8
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBN2 NFIX NR2F1

5.23e-04196363cbfe01ba8071864e19b37028236ae35789f630fe
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CSTF2 TAF5 HNRNPAB

5.23e-04196363de70cc301a8cbaedb0a5ea4a6442dcdaa477822d
ToppCellLAM-Epithelial-AT2|LAM / Condition, Lineage and Cell class

NKX2-1 DMKN NFIX

5.23e-041963639165041ef3d56b4d069497fee03dd1c6e273211d
ToppCellLAM-Epithelial|LAM / Condition, Lineage and Cell class

NKX2-1 DMKN NFIX

5.31e-04197363e5cf07061f6d9db7f12ac17209b267373fa2270b
ToppCellILEUM-non-inflamed-(8)_Fibroblast-(8)_Pericytes|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SNRK KCNA5 NR2F1

5.31e-04197363608328608cef82adc867a449216839622253d486
ToppCelltumor_Lung-Epithelial_cells-tS1|tumor_Lung / Location, Cell class and cell subclass

NKX2-1 DMKN NFIX

5.31e-041973638336e6647604e4bdd1596ea554c22203d13782e9
ToppCellAT2_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

NKX2-1 DMKN NFIX

5.31e-041973638b5d4e1c33a57c899c51feb9a6f347232f8910a3
ToppCell11.5-Airway-Mesenchymal-Mesenchyme_SERPINF1-high|Airway / Age, Tissue, Lineage and Cell class

FBN2 KCNA5 NFIX

5.31e-041973639a053a32ff9c3a85ef9a3382453acd619cc48546
ToppCellAT2_cells|World / lung cells shred on cell class, cell subclass, sample id

NKX2-1 DMKN NFIX

5.39e-0419836392c569c3b8a9fca2d4682cbf77ee8149bcc0a80a
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FUS COL6A6 NR2F1

5.39e-04198363d9ffc6589ed510ffa60c591f2a0fe123210f1455
ToppCellmetastatic_Brain-Epithelial_cells|metastatic_Brain / Location, Cell class and cell subclass

RAB2A NKX2-1 DMKN

5.46e-041993635c0cd611dbf2014e0ae6ce9fe8b619ceb4006e43
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBN2 COL6A6 DMKN

5.46e-04199363edba1833ef5c4ca122d7c32f97670314e005f93b
ToppCellcontrol-unassigned|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TAF5 TCF20 DMKN

5.46e-0419936350e2da35edff1aadef939cfbd4549f73c1a07717
ToppCellnormal_Pleural_Fluid-Epithelial_cells|normal_Pleural_Fluid / Location, Cell class and cell subclass

NKX2-1 DMKN NR2F1

5.46e-04199363564ba7acd03be2d6e4d0850cb2c7237a788dc275
ToppCellEpithelial_cells|World / lung cells shred on cell class, cell subclass, sample id

NKX2-1 DMKN NFIX

5.46e-04199363bbe69e44b7970f57628365ae771790f2b13d0cae
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBN2 NFIX NR2F1

5.46e-041993638d71e1fc92ee24deedf23fbb1a85a7fba0d8d436
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBN2 NFIX NR2F1

5.46e-0419936349690494270981eec5b5261c59e0545dff90cc21
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FUS COL6A6 NR2F1

5.46e-04199363c007cd51577e31553395ceaed70ad447e5854546
ToppCellmetastatic_Brain-Epithelial_cells-Malignant_cells|metastatic_Brain / Location, Cell class and cell subclass

RAB2A NKX2-1 DMKN

5.46e-0419936356df2b342c77b33299cfb407e1e05f42940f2946
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-1|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

COL6A6 NFIX NR2F1

5.55e-04200363c3d4ce70ab51d74c9fe2f5864e52a4a9d7570e10
ToppCellParenchyma_COVID-19-Stromal-TX-Fibroblasts-1|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

COL6A6 NFIX NR2F1

5.55e-0420036325d3865aa2ced11a5ed40013e83b47d942fdf582
ToppCellcellseq-Epithelial|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NKX2-1 DMKN NFIX

5.55e-04200363e4204c4b864346f47d76b0f0faae96f04fed5082
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-1-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

COL6A6 NFIX NR2F1

5.55e-04200363137f8f9d255c66336d4f8b44b2e3f3de721f2bf0
ToppCellBiopsy_Control_(H.)-Epithelial|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

NKX2-1 DMKN NFIX

5.55e-042003630afd93c4fdcc118bcfa77f3b59f6ff7d9293a7a4
ComputationalNeighborhood of ESPL1

TARDBP FUS HNRNPAB HCFC1

6.36e-0661224MORF_ESPL1
Druglomustine; Down 200; 100uM; MCF7; HT_HG-U133A

GATA4 SNRK NR2F1 NYNRIN CREBZF

1.20e-051913657045_DN
DrugCinoxacin [28657-80-9]; Down 200; 15.2uM; HL60; HT_HG-U133A

SNRK C14orf93 FUS GLG1 CREBZF

1.23e-051923652722_DN
DrugSulfachloropyridazine [80-32-0]; Down 200; 14uM; PC3; HT_HG-U133A

STRN3 C14orf93 FBN2 RAB2A NFIX

1.40e-051973653769_DN
DrugDiphenylpyraline hydrochloride [132-18-3]; Up 200; 12.6uM; PC3; HT_HG-U133A

SNRK C14orf93 HOXD3 RAB2A NYNRIN

1.40e-051973654299_UP
DrugIndapamide [26807-65-8]; Down 200; 10.6uM; MCF7; HT_HG-U133A

SP1 STRN3 C14orf93 GLG1 CREBZF

1.47e-051993652322_DN
Diseasecortical surface area measurement

SP1 STRN3 ARID1B FBN2 KCNA5 TAF5 NFIX NR2F1 SP7

1.99e-051345359EFO_0010736
DiseaseFrontotemporal Dementia With Motor Neuron Disease

TARDBP FUS

3.81e-058352C3888102
Diseasefrontotemporal dementia (implicated_via_orthology)

TARDBP FUS

8.95e-0512352DOID:9255 (implicated_via_orthology)
Diseasecortical surface area measurement, neuroimaging measurement

STRN3 KCNA5 NFIX NR2F1

1.48e-04227354EFO_0004346, EFO_0010736
DiseaseAmyotrophic lateral sclerosis

TARDBP FUS

1.84e-0417352cv:C0002736
DiseaseATRIAL FIBRILLATION, FAMILIAL, 1 (disorder)

GATA4 KCNA5

3.11e-0422352C1843687
DiseaseAmyotrophic Lateral Sclerosis With Dementia

TARDBP FUS

5.44e-0429352C0393554
Diseaseamyotrophic lateral sclerosis (implicated_via_orthology)

TARDBP FUS

5.82e-0430352DOID:332 (implicated_via_orthology)
DiseaseAmyotrophic Lateral Sclerosis, Guam Form

TARDBP FUS

6.22e-0431352C0543859
DiseaseHirschsprung Disease

ARID1B NKX2-1

6.22e-0431352C0019569
Diseaseamyotrophic lateral sclerosis (is_implicated_in)

TARDBP FUS

6.63e-0432352DOID:332 (is_implicated_in)
Diseasehypospadias

SP1 SP7

9.85e-0439352EFO_0004209
DiseaseDiaphragmatic Hernia

GATA4 NKX2-1

1.09e-0341352C0019284

Protein segments in the cluster

PeptideGeneStartEntry
PISNNNSLGGAGGGA

ARID1B

216

Q8NFD5
GGSQPGGFSPGQNQV

CSTF2

516

P33240
QQQLQQDSGGGGGGG

NKX2-1

226

P43699
GGGGGGTGCPQQQQA

NKX2-1

236

P43699
ATHAGNQGGQQAGGG

RAB2A

196

P61019
RGGGGGAGEQQQQAG

NR2F1

31

P10589
ATSNGGTGQPEGGQQ

HCFC1

1336

P51610
HEGQNQAGVGGAGPG

PSKH2

21

Q96QS6
GSGQATGQPNGSGQG

NFIX

411

Q14938
GQSQGQSQGPGSGDT

MAPK8IP1

141

Q9UQF2
NQDQSGGGGSGGYGQ

FUS

196

P35637
GQSPGHGQRGSGSGQ

HRNR

421

Q86YZ3
GRQGSGSGQSPGHGQ

HRNR

1116

Q86YZ3
GRQGSGSGQSPGHGQ

HRNR

1586

Q86YZ3
GRQGSGSGQSPGHGQ

HRNR

2056

Q86YZ3
GRQGSGSGQSPGHGQ

HRNR

2526

Q86YZ3
GNSQGGGGGSQPPGL

HOXD3

96

P31249
GGGGSQPPGLNSEQQ

HOXD3

101

P31249
QSPGQCGDNTGAGSG

LRRC66

486

Q68CR7
SGGAASGAGPGTQQG

GATA4

71

P43694
GQAGGGGPAGQQLPQ

GLG1

51

Q92896
LAEQQPGGGGGGQNG

KCNA5

376

P22460
PGGGGGGQNGQQAMS

KCNA5

381

P22460
FGSQGGLGGQGQGNP

DMKN

151

Q6E0U4
GLGGQGQGNPGGLGT

DMKN

156

Q6E0U4
GGNGGPPNFGTNTQG

DMKN

196

Q6E0U4
SETNGGNTGSQGGNP

C14orf93

26

Q9H972
GTGGNGFAPSGNGNG

FBN2

436

P35556
GGEAGNQGRLGSQGN

COL6A6

1611

A6NMZ7
GQGQAGRQGPQSSGT

NYNRIN

716

Q9P2P1
GNGRGSGGGQGSNGQ

IRS4

496

O14654
GQGSRGGQGSNGQGS

IRS4

526

O14654
GGQGSNGQGSGGNQC

IRS4

531

O14654
GAGEGSGGTTNNGPN

TAF5

31

Q15542
SGGTTNNGPNGGGGN

TAF5

36

Q15542
NNGPNGGGGNVAASS

TAF5

41

Q15542
QQGPGGNLGLSPGGN

STRN3

21

Q13033
GGGGGGGGQSQSWNQ

HNRNPAB

256

Q99729
NSRGGGAGLGNNQGS

TARDBP

291

Q13148
GAGLGNNQGSNMGGG

TARDBP

296

Q13148
VGGNNGGNGNGGGAF

SP1

21

P08047
NNAGGGSPSSGSGGN

SNRK

601

Q9NRH2
GGGPGDAQGQNDGNT

TAS1R3

831

Q7RTX0
NWLGGGQGQGDGLQG

SP7

166

Q8TDD2
GQGQGDGLQGTLPTG

SP7

171

Q8TDD2
QQGQGAGSAPSGSGS

TNKS1BP1

526

Q9C0C2
GGGGGGGSGNDNNQA

CREBZF

191

Q9NS37
NGEGNGQSGHSAAGP

TCF20

676

Q9UGU0
GTGGQQRGGEGQQSS

XKR5

526

Q6UX68
QQLGGQGAAPGAGGG

UBE2Q1

16

Q7Z7E8
NSQVSVNGGAGGGGS

KRT77

491

Q7Z794