Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	flippase activity	ABCA3 ABCA4 ATP10A ATP10D	1.19e-07	17	55	4	GO:0140327
GeneOntologyMolecularFunction	ATPase-coupled intramembrane lipid transporter activity	ABCA3 ABCA4 ATP10A ATP10D	1.00e-06	28	55	4	GO:0140326
GeneOntologyMolecularFunction	glycerophospholipid flippase activity	ABCA3 ABCA4 ATP10A	7.04e-06	14	55	3	GO:0140333
GeneOntologyMolecularFunction	intramembrane lipid transporter activity	ABCA3 ABCA4 ATP10A ATP10D	1.17e-05	51	55	4	GO:0140303
GeneOntologyMolecularFunction	glycosylceramide flippase activity	ATP10A ATP10D	2.23e-05	3	55	2	GO:0140351
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	TAOK2 DCAF1 PHKA1 LIMK1 LIMK2 LRRK2 STK38 TAOK1	2.82e-05	446	55	8	GO:0004674
GeneOntologyMolecularFunction	protein kinase activity	TAOK2 DCAF1 PHKA1 LIMK1 LIMK2 LRRK2 STK38 TAOK1 EPHA4	3.48e-05	600	55	9	GO:0004672
GeneOntologyMolecularFunction	kinase activity	TAOK2 DCAF1 PHKA1 LIMK1 LIMK2 LRRK2 STK38 MAGI3 TAOK1 EPHA4	3.89e-05	764	55	10	GO:0016301
GeneOntologyMolecularFunction	protein serine kinase activity	TAOK2 DCAF1 LIMK1 LIMK2 LRRK2 STK38 TAOK1	5.93e-05	363	55	7	GO:0106310
GeneOntologyMolecularFunction	phosphatidylcholine flippase activity	ABCA3 ATP10A	1.11e-04	6	55	2	GO:0140345
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	TAOK2 DCAF1 PHKA1 LIMK1 LIMK2 LRRK2 STK38 TAOK1 EPHA4	1.25e-04	709	55	9	GO:0016773
GeneOntologyMolecularFunction	lipid transporter activity	ABCA3 ABCA4 ABCA13 ATP10A ATP10D	2.02e-04	196	55	5	GO:0005319
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	TAOK2 DCAF1 PHKA1 LIMK1 LIMK2 LRRK2 STK38 MAGI3 TAOK1 EPHA4	2.13e-04	938	55	10	GO:0016772
GeneOntologyMolecularFunction	ATP-dependent activity	ABCA3 ABCA4 ABCA13 DNAH17 ATP10A TOP2A DNAH14 ATP10D	2.60e-04	614	55	8	GO:0140657
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCA3 ABCA4 ABCA13	3.33e-04	49	55	3	GO:0140359
GeneOntologyMolecularFunction	magnesium ion binding	LRRK2 STK38 ATP10A TOP2A ATP10D	5.84e-04	247	55	5	GO:0000287
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH17 DNAH14	1.11e-03	18	55	2	GO:0008569
GeneOntologyMolecularFunction	phospholipid transporter activity	ABCA3 ABCA4 ATP10A	1.12e-03	74	55	3	GO:0005548
GeneOntologyMolecularFunction	protein serine/threonine kinase activator activity	TAOK2 MTCP1 TAOK1	1.30e-03	78	55	3	GO:0043539
GeneOntologyMolecularFunction	sphingolipid transporter activity	ATP10A ATP10D	1.37e-03	20	55	2	GO:0046624
GeneOntologyMolecularFunction	phosphatidylcholine transporter activity	ABCA3 ATP10A	1.37e-03	20	55	2	GO:0008525
GeneOntologyMolecularFunction	tau-protein kinase activity	TAOK2 TAOK1	1.66e-03	22	55	2	GO:0050321
GeneOntologyMolecularFunction	MAP kinase kinase kinase activity	TAOK2 LRRK2	2.50e-03	27	55	2	GO:0004709
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH17 DNAH14	2.69e-03	28	55	2	GO:0051959
GeneOntologyMolecularFunction	amyloid-beta binding	CACNA1A SCARB1 EPHA4	2.80e-03	102	55	3	GO:0001540
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCA3 ABCA4 ABCA13	3.38e-03	109	55	3	GO:0042626
GeneOntologyMolecularFunction	Wnt-protein binding	SFRP1 SFRP5	3.95e-03	34	55	2	GO:0017147
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH17 DNAH14	4.66e-03	37	55	2	GO:0045505
GeneOntologyMolecularFunction	frizzled binding	SFRP1 MAGI3	5.98e-03	42	55	2	GO:0005109
GeneOntologyBiologicalProcess	phospholipid transport	ABCA3 ABCA4 SCARB1 ATP10A ATP10D	9.24e-06	106	55	5	GO:0015914
GeneOntologyBiologicalProcess	regulation of MAP kinase activity	SFRP1 SFRP5 LRRK2 STK38 MAGI3 EPHA4	1.27e-05	194	55	6	GO:0043405
GeneOntologyBiologicalProcess	lipid translocation	ABCA3 ABCA4 ATP10A ATP10D	1.97e-05	60	55	4	GO:0034204
GeneOntologyBiologicalProcess	regulation of membrane lipid distribution	ABCA3 ABCA4 ATP10A ATP10D	2.71e-05	65	55	4	GO:0097035
GeneOntologyBiologicalProcess	regulation of JUN kinase activity	SFRP1 SFRP5 MAGI3 EPHA4	3.06e-05	67	55	4	GO:0043506
GeneOntologyBiologicalProcess	negative regulation of Wnt signaling pathway, planar cell polarity pathway	SFRP1 SFRP5	4.17e-05	4	55	2	GO:0141113
GeneOntologyBiologicalProcess	regulation of MAPK cascade	TAOK2 SFRP1 SFRP5 LRRK2 STK38 MAGI3 TAOK1 ECE1 AR EPHA4	5.11e-05	815	55	10	GO:0043408
GeneOntologyBiologicalProcess	lipid transport	ABCA3 ABCA4 ABCA13 SCARB1 STARD10 NMUR2 ATP10A ATP10D	5.49e-05	506	55	8	GO:0006869
GeneOntologyBiologicalProcess	organophosphate ester transport	ABCA3 ABCA4 SCARB1 ATP10A ATP10D	7.12e-05	162	55	5	GO:0015748
GeneOntologyBiologicalProcess	isoprenoid transport	ABCA4 SCARB1	1.04e-04	6	55	2	GO:0046864
GeneOntologyBiologicalProcess	terpenoid transport	ABCA4 SCARB1	1.04e-04	6	55	2	GO:0046865
GeneOntologyBiologicalProcess	lipid localization	ABCA3 ABCA4 ABCA13 SCARB1 STARD10 NMUR2 ATP10A ATP10D	1.18e-04	565	55	8	GO:0010876
GeneOntologyBiologicalProcess	MAPK cascade	TAOK2 SFRP1 SFRP5 LRRK2 STK38 MAGI3 TAOK1 ECE1 AR EPHA4	1.53e-04	930	55	10	GO:0000165
GeneOntologyBiologicalProcess	JNK cascade	TAOK2 SFRP1 SFRP5 LRRK2 TAOK1	1.83e-04	198	55	5	GO:0007254
GeneOntologyBiologicalProcess	convergent extension involved in axis elongation	SFRP1 SFRP5	1.93e-04	8	55	2	GO:0060028
GeneOntologyBiologicalProcess	negative regulation of non-canonical Wnt signaling pathway	SFRP1 SFRP5	2.48e-04	9	55	2	GO:2000051
GeneOntologyBiologicalProcess	regulation of phosphatidylcholine metabolic process	ABCA3 SCARB1	3.10e-04	10	55	2	GO:0150172
GeneOntologyBiologicalProcess	regulation of protein serine/threonine kinase activity	SFRP1 SFRP5 LRRK2 STK38 MAGI3 EPHA4	3.71e-04	358	55	6	GO:0071900
GeneOntologyBiologicalProcess	phospholipid translocation	ABCA4 ATP10A ATP10D	4.27e-04	55	55	3	GO:0045332
GeneOntologyBiologicalProcess	negative regulation of MAP kinase activity	SFRP1 SFRP5 STK38	4.27e-04	55	55	3	GO:0043407
GeneOntologyBiologicalProcess	neuron-neuron synaptic transmission	CACNA1A DLGAP2	4.53e-04	12	55	2	GO:0007270
GeneOntologyBiologicalProcess	DNA damage checkpoint signaling	TAOK2 CUL4A STK38 TAOK1	4.75e-04	136	55	4	GO:0000077
GeneOntologyBiologicalProcess	positive regulation of synaptic vesicle endocytosis	ABCA13 LRRK2	5.34e-04	13	55	2	GO:1900244
GeneOntologyBiologicalProcess	regulation of anatomical structure morphogenesis	TAOK2 CACNA1A LIMK1 SFRP1 SFRP5 ANXA7 LRRK2 ATP10A AR EPHA4	5.43e-04	1090	55	10	GO:0022603
GeneOntologyBiologicalProcess	DNA integrity checkpoint signaling	TAOK2 CUL4A STK38 TAOK1	6.05e-04	145	55	4	GO:0031570
GeneOntologyCellularComponent	axonal growth cone	TAOK2 LIMK1 EPHA4	2.26e-04	45	55	3	GO:0044295
GeneOntologyCellularComponent	cytoplasmic vesicle membrane	TAOK2 ABCA3 ABCA4 ABCA13 SCARB1 ANXA7 LRRK2 MR1 ECE1 DAGLA EPHA4	5.12e-04	1307	55	11	GO:0030659
GeneOntologyCellularComponent	vesicle membrane	TAOK2 ABCA3 ABCA4 ABCA13 SCARB1 ANXA7 LRRK2 MR1 ECE1 DAGLA EPHA4	5.74e-04	1325	55	11	GO:0012506
GeneOntologyCellularComponent	phospholipid-translocating ATPase complex	ATP10A ATP10D	6.06e-04	14	55	2	GO:1990531
Domain	ABC_A	ABCA3 ABCA4 ABCA13	4.93e-06	12	54	3	IPR026082
Domain	Protein_kinase_ATP_BS	TAOK2 LIMK1 LIMK2 LRRK2 STK38 TAOK1 EPHA4	1.04e-04	379	54	7	IPR017441
Domain	PROTEIN_KINASE_ATP	TAOK2 LIMK1 LIMK2 LRRK2 STK38 TAOK1 EPHA4	3.38e-04	459	54	7	PS00107
Domain	ABC_tran	ABCA3 ABCA4 ABCA13	3.60e-04	48	54	3	PF00005
Domain	ABC_TRANSPORTER_2	ABCA3 ABCA4 ABCA13	3.60e-04	48	54	3	PS50893
Domain	Hydrolase_3	ATP10A ATP10D	3.64e-04	10	54	2	PF08282
Domain	ABC_TRANSPORTER_1	ABCA3 ABCA4 ABCA13	3.83e-04	49	54	3	PS00211
Domain	ABC_transporter-like	ABCA3 ABCA4 ABCA13	4.07e-04	50	54	3	IPR003439
Domain	BAH	BAHD1 BAHCC1	4.44e-04	11	54	2	SM00439
Domain	BAH	BAHD1 BAHCC1	4.44e-04	11	54	2	PF01426
Domain	BAH	BAHD1 BAHCC1	4.44e-04	11	54	2	PS51038
Domain	BAH_dom	BAHD1 BAHCC1	4.44e-04	11	54	2	IPR001025
Domain	Prot_kinase_dom	TAOK2 LIMK1 LIMK2 LRRK2 STK38 TAOK1 EPHA4	4.94e-04	489	54	7	IPR000719
Domain	PROTEIN_KINASE_DOM	TAOK2 LIMK1 LIMK2 LRRK2 STK38 TAOK1 EPHA4	5.18e-04	493	54	7	PS50011
Domain	Ser/Thr_kinase_AS	TAOK2 LIMK1 LIMK2 LRRK2 STK38 TAOK1	5.57e-04	357	54	6	IPR008271
Domain	PROTEIN_KINASE_ST	TAOK2 LIMK1 LIMK2 LRRK2 STK38 TAOK1	6.00e-04	362	54	6	PS00108
Domain	P_typ_ATPase_c	ATP10A ATP10D	7.30e-04	14	54	2	IPR032630
Domain	P-type_ATPase_N	ATP10A ATP10D	7.30e-04	14	54	2	IPR032631
Domain	P-type_ATPase_IV	ATP10A ATP10D	7.30e-04	14	54	2	IPR006539
Domain	PhoLip_ATPase_C	ATP10A ATP10D	7.30e-04	14	54	2	PF16212
Domain	PhoLip_ATPase_N	ATP10A ATP10D	7.30e-04	14	54	2	PF16209
Domain	Pkinase	TAOK2 LIMK1 LIMK2 LRRK2 STK38 TAOK1	7.83e-04	381	54	6	PF00069
Domain	Kinase-like_dom	TAOK2 LIMK1 LIMK2 LRRK2 STK38 TAOK1 EPHA4	9.06e-04	542	54	7	IPR011009
Domain	Frizzled/SFRP	SFRP1 SFRP5	9.59e-04	16	54	2	IPR015526
Domain	C345C	SFRP1 SFRP5	1.09e-03	17	54	2	SM00643
Domain	-	CNTNAP1 F5 EPHA4	1.23e-03	73	54	3	2.60.120.260
Domain	NTR	SFRP1 SFRP5	1.36e-03	19	54	2	PF01759
Domain	Netrin_module_non-TIMP	SFRP1 SFRP5	1.36e-03	19	54	2	IPR018933
Domain	FRI	SFRP1 SFRP5	1.51e-03	20	54	2	SM00063
Domain	FA58C	CNTNAP1 F5	1.66e-03	21	54	2	SM00231
Domain	-	SFRP1 SFRP5	1.66e-03	21	54	2	1.10.2000.10
Domain	FA58C_3	CNTNAP1 F5	1.66e-03	21	54	2	PS50022
Domain	FA58C_1	CNTNAP1 F5	1.66e-03	21	54	2	PS01285
Domain	FA58C_2	CNTNAP1 F5	1.66e-03	21	54	2	PS01286
Domain	NTR	SFRP1 SFRP5	2.00e-03	23	54	2	PS50189
Domain	Netrin_domain	SFRP1 SFRP5	2.00e-03	23	54	2	IPR001134
Domain	F5_F8_type_C	CNTNAP1 F5	2.17e-03	24	54	2	PF00754
Domain	Frizzled_dom	SFRP1 SFRP5	2.17e-03	24	54	2	IPR020067
Domain	FA58C	CNTNAP1 F5	2.17e-03	24	54	2	IPR000421
Domain	FZ	SFRP1 SFRP5	2.17e-03	24	54	2	PS50038
Domain	Fz	SFRP1 SFRP5	2.17e-03	24	54	2	PF01392
Domain	Galactose-bd-like	CNTNAP1 F5 EPHA4	2.54e-03	94	54	3	IPR008979
Domain	TIMP-like_OB-fold	SFRP1 SFRP5	2.55e-03	26	54	2	IPR008993
Domain	S_TKc	TAOK2 LRRK2 STK38 TAOK1 EPHA4	3.73e-03	359	54	5	SM00220
Domain	-	ATP10A ATP10D	3.85e-03	32	54	2	3.40.1110.10
Domain	-	ATP10A ATP10D	3.85e-03	32	54	2	2.70.150.10
Domain	ATPase_P-typ_cyto_domN	ATP10A ATP10D	4.59e-03	35	54	2	IPR023299
Domain	P_typ_ATPase	ATP10A ATP10D	4.85e-03	36	54	2	IPR001757
Domain	ATPase_P-typ_P_site	ATP10A ATP10D	4.85e-03	36	54	2	IPR018303
Domain	ATPASE_E1_E2	ATP10A ATP10D	4.85e-03	36	54	2	PS00154
Domain	ATPase_P-typ_transduc_dom_A	ATP10A ATP10D	5.12e-03	37	54	2	IPR008250
Domain	E1-E2_ATPase	ATP10A ATP10D	5.12e-03	37	54	2	PF00122
Pubmed	The small GTPase RhoA regulates the LIMK1/2-cofilin pathway to modulate cytoskeletal dynamics in oocyte meiosis.	LIMK1 LIMK2	2.64e-06	2	57	2	29319181
Pubmed	Different activity regulation and subcellular localization of LIMK1 and LIMK2 during cell cycle transition.	LIMK1 LIMK2	2.64e-06	2	57	2	16455074
Pubmed	Cloning and biochemical characterization of LIMK-2, a protein kinase containing two LIM domains.	LIMK1 LIMK2	2.64e-06	2	57	2	9089416
Pubmed	Decreased expression and aberrant hypermethylation of the SFRP genes in human gastric cancer.	SFRP1 SFRP5	2.64e-06	2	57	2	21830441
Pubmed	LIMK1 and LIMK2 are important for metastatic behavior and tumor cell-induced angiogenesis of pancreatic cancer cells.	LIMK1 LIMK2	2.64e-06	2	57	2	20047470
Pubmed	Involvement of LIMK1/2 in actin assembly during mouse embryo development.	LIMK1 LIMK2	2.64e-06	2	57	2	29943641
Pubmed	Transient inhibition of LIMKs significantly attenuated central sensitization and delayed the development of chronic pain.	LIMK1 LIMK2	2.64e-06	2	57	2	28669900
Pubmed	Self-association of LIM-kinase 1 mediated by the interaction between an N-terminal LIM domain and a C-terminal kinase domain.	LIMK1 LIMK2	2.64e-06	2	57	2	8980133
Pubmed	LIM kinase inhibition reduces breast cancer growth and invasiveness but systemic inhibition does not reduce metastasis in mice.	LIMK1 LIMK2	2.64e-06	2	57	2	23239465
Pubmed	The Diagnostic and Prognostic Value of LIMK1/2: A Pan-Cancer Analysis.	LIMK1 LIMK2	2.64e-06	2	57	2	34686503
Pubmed	Phosphorylated LIM kinases colocalize with gamma-tubulin in centrosomes during early stages of mitosis.	LIMK1 LIMK2	2.64e-06	2	57	2	18000399
Pubmed	Topoisomerase 2 Alpha Cooperates with Androgen Receptor to Contribute to Prostate Cancer Progression.	AR TOP2A	2.64e-06	2	57	2	26560244
Pubmed	Elevated LIM kinase 1 in nonmetastatic prostate cancer reflects its role in facilitating androgen receptor nuclear translocation.	LIMK1 LIMK2	2.64e-06	2	57	2	25344584
Pubmed	Suppression of LIM Kinase 1 and LIM Kinase 2 Limits Glioblastoma Invasion.	LIMK1 LIMK2	2.64e-06	2	57	2	31641031
Pubmed	Yeast and human P4-ATPases transport glycosphingolipids using conserved structural motifs.	ATP10A ATP10D	2.64e-06	2	57	2	30530492
Pubmed	Targeting TAO Kinases Using a New Inhibitor Compound Delays Mitosis and Induces Mitotic Cell Death in Centrosome Amplified Breast Cancer Cells.	TAOK2 TAOK1	2.64e-06	2	57	2	28830982
Pubmed	ATP10A deficiency results in male-specific infertility in mice.	ATP10A ATP10D	2.64e-06	2	57	2	38415274
Pubmed	LIM kinases: function, regulation and association with human disease.	LIMK1 LIMK2	2.64e-06	2	57	2	17294230
Pubmed	GPER stabilizes F-actin cytoskeleton and activates TAZ via PLCβ-PKC and Rho/ROCK-LIMK-Cofilin pathway.	LIMK1 LIMK2	7.91e-06	3	57	2	31277940
Pubmed	Multifaceted activity of HIV Vpr/Vpx proteins: the current view of their virological functions.	DCAF1 CUL4A	7.91e-06	3	57	2	20069611
Pubmed	LIMK Regulates Tumor-Cell Invasion and Matrix Degradation Through Tyrosine Phosphorylation of MT1-MMP.	LIMK1 LIMK2	7.91e-06	3	57	2	27116935
Pubmed	SARPs: a family of secreted apoptosis-related proteins.	SFRP1 SFRP5	7.91e-06	3	57	2	9391078
Pubmed	Regulation of ADF/cofilin phosphorylation and synaptic function by LIM-kinase.	LIMK1 LIMK2	7.91e-06	3	57	2	15458846
Pubmed	Neuroligin 1 regulates spines and synaptic plasticity via LIMK1/cofilin-mediated actin reorganization.	LIMK1 LIMK2	7.91e-06	3	57	2	26880202
Pubmed	Enhanced striatal dopamine transmission and motor performance with LRRK2 overexpression in mice is eliminated by familial Parkinson's disease mutation G2019S.	SFRP1 LRRK2	7.91e-06	3	57	2	20130188
Pubmed	Nischarin inhibits LIM kinase to regulate cofilin phosphorylation and cell invasion.	LIMK1 LIMK2	7.91e-06	3	57	2	18332102
Pubmed	Isolation of TAO1, a protein kinase that activates MEKs in stress-activated protein kinase cascades.	TAOK2 TAOK1	7.91e-06	3	57	2	9786855
Pubmed	Silencing of secreted frizzled-related protein genes in MSI colorectal carcinogenesis.	SFRP1 SFRP5	7.91e-06	3	57	2	18795670
Pubmed	TAO kinases mediate activation of p38 in response to DNA damage.	TAOK2 TAOK1	7.91e-06	3	57	2	17396146
Pubmed	NGPF2 triggers synaptic scaling up through ALK-LIMK-cofilin-mediated mechanisms.	LIMK1 LIMK2	7.91e-06	3	57	2	34407403
Pubmed	Epigenetic inactivation of SFRP genes in oral squamous cell carcinoma.	SFRP1 SFRP5	7.91e-06	3	57	2	18497987
Pubmed	HIV1 Vpr arrests the cell cycle by recruiting DCAF1/VprBP, a receptor of the Cul4-DDB1 ubiquitin ligase.	DCAF1 CUL4A	7.91e-06	3	57	2	17314515
Pubmed	HIV1 Vpr arrests the cell cycle by recruiting DCAF1/VprBP, a receptor of the Cul4-DDB1 ubiquitin ligase.	DCAF1 CUL4A	7.91e-06	3	57	2	19667756
Pubmed	Williams-Beuren syndrome: a challenge for genotype-phenotype correlations.	LIMK1 GTF2IRD1	7.91e-06	3	57	2	12952863
Pubmed	Prostate-derived sterile 20-like kinases (PSKs/TAOKs) phosphorylate tau protein and are activated in tangle-bearing neurons in Alzheimer disease.	TAOK2 TAOK1	7.91e-06	3	57	2	23585562
Pubmed	HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase.	DCAF1 CUL4A	7.91e-06	3	57	2	17630831
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	UBE4A DNAH17 LTN1 MAGI3 TAOK1 TTC39A ATP10A	1.58e-05	493	57	7	15368895
Pubmed	Lentiviral Vpx accessory factor targets VprBP/DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infection.	DCAF1 CUL4A	1.58e-05	4	57	2	18464893
Pubmed	The HIV1 protein Vpr acts to promote G2 cell cycle arrest by engaging a DDB1 and Cullin4A-containing ubiquitin ligase complex using VprBP/DCAF1 as an adaptor.	DCAF1 CUL4A	1.58e-05	4	57	2	17620334
Pubmed	Identification and characterization of a novel family of serine/threonine kinases containing two N-terminal LIM motifs.	LIMK1 LIMK2	1.58e-05	4	57	2	8537403
Pubmed	DCAF1 (VprBP): emerging physiological roles for a unique dual-service E3 ubiquitin ligase substrate receptor.	DCAF1 CUL4A	1.58e-05	4	57	2	30590706
Pubmed	Modulation of NKG2D-mediated cytotoxic functions of natural killer cells by viral protein R from HIV-1 primary isolates.	DCAF1 CUL4A	1.58e-05	4	57	2	21957298
Pubmed	Hypermethylation and aberrant expression of secreted frizzled-related protein genes in pancreatic cancer.	SFRP1 SFRP5	1.58e-05	4	57	2	18528941
Pubmed	Isolation of the protein kinase TAO2 and identification of its mitogen-activated protein kinase/extracellular signal-regulated kinase kinase binding domain.	TAOK2 TAOK1	1.58e-05	4	57	2	10497253
Pubmed	Keratinocyte migration in the developing eyelid requires LIMK2.	LIMK1 LIMK2	1.58e-05	4	57	2	23071748
Pubmed	DDB1 and Cul4A are required for human immunodeficiency virus type 1 Vpr-induced G2 arrest.	DCAF1 CUL4A	1.58e-05	4	57	2	17626091
Pubmed	Frequent concomitant epigenetic silencing of SOX1 and secreted frizzled-related proteins (SFRPs) in human hepatocellular carcinoma.	SFRP1 SFRP5	1.58e-05	4	57	2	23215838
Pubmed	Epigenetic dysregulation of secreted Frizzled-related proteins in multiple myeloma.	SFRP1 SFRP5	1.58e-05	4	57	2	19299079
Pubmed	A novel Rho-dependent pathway that drives interaction of fascin-1 with p-Lin-11/Isl-1/Mec-3 kinase (LIMK) 1/2 to promote fascin-1/actin binding and filopodia stability.	LIMK1 LIMK2	1.58e-05	4	57	2	22883572
Pubmed	HIV-1 Vpr induces the K48-linked polyubiquitination and proteasomal degradation of target cellular proteins to activate ATR and promote G2 arrest.	DCAF1 CUL4A	1.58e-05	4	57	2	20089662
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	CUL4A SCARB1 ANXA7 STARD10 MAGI3 GTF2IRD1 ATP10A DAGLA AR DNAH14 XPO7	2.56e-05	1489	57	11	28611215
Pubmed	TPPP acts downstream of RhoA-ROCK-LIMK2 to regulate astral microtubule organization and spindle orientation.	LIMK1 LIMK2	2.63e-05	5	57	2	22328514
Pubmed	Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38.	TAOK2 TAOK1	2.63e-05	5	57	2	13679851
Pubmed	Akt Phosphorylates Wnt Coactivator and Chromatin Effector Pygo2 at Serine 48 to Antagonize Its Ubiquitin/Proteasome-mediated Degradation.	DCAF1 CUL4A	2.63e-05	5	57	2	26170450
Pubmed	Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus.	DCAF1 CUL4A	2.63e-05	5	57	2	20178741
Pubmed	NRIP/DCAF6 stabilizes the androgen receptor protein by displacing DDB2 from the CUL4A-DDB1 E3 ligase complex in prostate cancer.	CUL4A AR	2.63e-05	5	57	2	28212551
Pubmed	Cyclin L2 is a critical HIV dependency factor in macrophages that controls SAMHD1 abundance.	DCAF1 CUL4A	2.63e-05	5	57	2	25532805
Pubmed	EZH2 generates a methyl degron that is recognized by the DCAF1/DDB1/CUL4 E3 ubiquitin ligase complex.	DCAF1 CUL4A	2.63e-05	5	57	2	23063525
Pubmed	LIM kinase 1 modulates cortical actin and CXCR4 cycling and is activated by HIV-1 to initiate viral infection.	LIMK1 LIMK2	2.63e-05	5	57	2	21321123
Pubmed	Isoform-specific and ubiquitination dependent recruitment of Tet1 to replicating heterochromatin modulates methylcytosine oxidation.	DCAF1 CUL4A	2.63e-05	5	57	2	36056023
Pubmed	Cullin4A and cullin4B are interchangeable for HIV Vpr and Vpx action through the CRL4 ubiquitin ligase complex.	DCAF1 CUL4A	2.63e-05	5	57	2	24719410
Pubmed	S100 Calcium Binding Protein A16 Promotes Cell Proliferation by triggering LATS1 ubiquitin degradation mediated by CUL4A ligase to inhibit Hippo pathway in Glioma development.	DCAF1 CUL4A	2.63e-05	5	57	2	37151881
Pubmed	Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma.	SFRP1 SFRP5	2.63e-05	5	57	2	18592156
Pubmed	Secreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancer.	SFRP1 AR	2.63e-05	5	57	2	19277043
Pubmed	Limelight on two HIV/SIV accessory proteins in macrophage infection: is Vpx overshadowing Vpr?	DCAF1 CUL4A	2.63e-05	5	57	2	20380700
Pubmed	Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex.	TAOK2 TAOK1	2.63e-05	5	57	2	22683681
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	GXYLT2 ABCA13 ECE1 F5 ATP10A GGCX	2.79e-05	361	57	6	26167880
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	CUL4A LIMK1 LIMK2 POGK STK38 EPHA4	3.29e-05	372	57	6	22939624
Pubmed	HIV-1 Vpr triggers mitochondrial destruction by impairing Mfn2-mediated ER-mitochondria interaction.	DCAF1 CUL4A	3.94e-05	6	57	2	22438978
Pubmed	CRL4-DDB1-VPRBP ubiquitin ligase mediates the stress triggered proteolysis of Mcm10.	DCAF1 CUL4A	3.94e-05	6	57	2	22570418
Pubmed	The CUL4-DDB1 ubiquitin ligase complex controls adult and embryonic stem cell differentiation and homeostasis.	DCAF1 CUL4A	3.94e-05	6	57	2	26613412
Pubmed	Combination analysis of hypermethylated Wnt-antagonist family genes as a novel epigenetic biomarker panel for bladder cancer detection.	SFRP1 SFRP5	3.94e-05	6	57	2	16609023
Pubmed	Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization.	LIMK1 LIMK2	3.94e-05	6	57	2	9655398
Pubmed	Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase.	LIMK1 LIMK2	3.94e-05	6	57	2	10436159
Pubmed	Role for p21-activated kinase PAK4 in development of the mammalian heart.	LIMK1 LIMK2	3.94e-05	6	57	2	22173944
Pubmed	Cofilin phosphorylation and actin reorganization activities of testicular protein kinase 2 and its predominant expression in testicular Sertoli cells.	LIMK1 LIMK2	3.94e-05	6	57	2	11418599
Pubmed	Nf1 RasGAP inhibition of LIMK2 mediates a new cross-talk between Ras and Rho pathways.	LIMK1 LIMK2	3.94e-05	6	57	2	23082153
Pubmed	HIV-1 Vpr loads uracil DNA glycosylase-2 onto DCAF1, a substrate recognition subunit of a cullin 4A-ring E3 ubiquitin ligase for proteasome-dependent degradation.	DCAF1 CUL4A	3.94e-05	6	57	2	20870715
Pubmed	Phospholipid Flippase ATP10A Translocates Phosphatidylcholine and Is Involved in Plasma Membrane Dynamics.	ATP10A ATP10D	3.94e-05	6	57	2	25947375
Pubmed	WNT pathway in oral cancer: epigenetic inactivation of WNT-inhibitors.	SFRP1 SFRP5	3.94e-05	6	57	2	20811686
Pubmed	The association of protein S Tokushima-K196E with a risk of deep vein thrombosis.	F5 GGCX	3.94e-05	6	57	2	20811787
Pubmed	HIV-1 Vpr Reprograms CLR4DCAF1 E3 Ubiquitin Ligase to Antagonize Exonuclease 1-Mediated Restriction of HIV-1 Infection.	DCAF1 CUL4A	3.94e-05	6	57	2	30352932
Pubmed	The prostate-derived sterile 20-like kinase (PSK) regulates microtubule organization and stability.	TAOK2 TAOK1	3.94e-05	6	57	2	12639963
Pubmed	Osmotic stress activates the TAK1-JNK pathway while blocking TAK1-mediated NF-kappaB activation: TAO2 regulates TAK1 pathways.	TAOK2 TAOK1	3.94e-05	6	57	2	16893890
Pubmed	HIV-1 Vpr up-regulates expression of ligands for the activating NKG2D receptor and promotes NK cell-mediated killing.	DCAF1 CUL4A	5.51e-05	7	57	2	20008788
Pubmed	VprBP targets Merlin to the Roc1-Cul4A-DDB1 E3 ligase complex for degradation.	DCAF1 CUL4A	5.51e-05	7	57	2	18332868
Pubmed	Targeting USP2 regulation of VPRBP-mediated degradation of p53 and PD-L1 for cancer therapy.	DCAF1 CUL4A	5.51e-05	7	57	2	37024504
Pubmed	The ins and outs of a polyglutamine neurodegenerative disease: spinocerebellar ataxia type 1 (SCA1).	CACNA1A AR	5.51e-05	7	57	2	10860780
Pubmed	Epigenetic silencing of SFRP1 and SFRP5 by hepatitis B virus X protein enhances hepatoma cell tumorigenicity through Wnt signaling pathway.	SFRP1 SFRP5	5.51e-05	7	57	2	24374650
Pubmed	Leucine-rich repeat kinase 2 interacts with p21-activated kinase 6 to control neurite complexity in mammalian brain.	LIMK1 LRRK2	5.51e-05	7	57	2	26375402
Pubmed	VprBP binds full-length RAG1 and is required for B-cell development and V(D)J recombination fidelity.	DCAF1 CUL4A	5.51e-05	7	57	2	22157821
Pubmed	Altered expression of CDC42 signaling pathway components in cortical layer 3 pyramidal cells in schizophrenia.	LIMK1 LIMK2	5.51e-05	7	57	2	25981171
Pubmed	The HIV-1 protein Vpr targets the endoribonuclease Dicer for proteasomal degradation to boost macrophage infection.	DCAF1 CUL4A	5.51e-05	7	57	2	23849790
Pubmed	HIV-1 Vpr triggers natural killer cell-mediated lysis of infected cells through activation of the ATR-mediated DNA damage response.	DCAF1 CUL4A	5.51e-05	7	57	2	19798433
Pubmed	SARP, a new alternatively spliced protein phosphatase 1 and DNA interacting protein.	SFRP1 SFRP5	5.51e-05	7	57	2	17123353
Pubmed	Hyperactivated Wnt-β-catenin signaling in the absence of sFRP1 and sFRP5 disrupts trophoblast differentiation through repression of Ascl2.	SFRP1 SFRP5	5.51e-05	7	57	2	33109217
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	TAOK2 MAGI3 BAHD1 BAHCC1	6.31e-05	130	57	4	12421765
Pubmed	Integration of a c-myc transgene results in disruption of the mouse Gtf2ird1 gene, the homologue of the human GTF2IRD1 gene hemizygously deleted in Williams-Beuren syndrome.	LIMK1 GTF2IRD1	7.34e-05	8	57	2	11352562
Pubmed	Activation of LIM kinases by myotonic dystrophy kinase-related Cdc42-binding kinase alpha.	LIMK1 LIMK2	7.34e-05	8	57	2	11340065
Pubmed	HIV-1 Vpr: a novel role in regulating RNA splicing.	DCAF1 CUL4A	7.34e-05	8	57	2	19275585
GeneFamily	ATP binding cassette subfamily A	ABCA3 ABCA4 ABCA13	3.32e-06	14	39	3	805
GeneFamily	Secreted frizzled-related proteins	SFRP1 SFRP5	4.52e-05	5	39	2	733
GeneFamily	ATPase phospholipid transporting	ATP10A ATP10D	4.68e-04	15	39	2	1210
GeneFamily	Dyneins, axonemal	DNAH17 DNAH14	6.04e-04	17	39	2	536
GeneFamily	Mitogen-activated protein kinase kinase kinases\|RAF family	TAOK2 TAOK1	1.21e-03	24	39	2	654
GeneFamily	PDZ domain containing	LIMK1 LIMK2 MAGI3	4.27e-03	152	39	3	1220
GeneFamily	LIM domain containing	LIMK1 LIMK2	7.18e-03	59	39	2	1218
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)\|367C / Donor, Lineage, Cell class and subclass (all cells)	ABCA3 SFRP5 SULT1C2 STARD10 LRRK2 TTC39A	1.18e-07	184	56	6	0ba243cbf69b4fe6ae100a7f0314317bec38026c
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	ABCA3 SFRP5 SULT1C2 STARD10 LRRK2 TTC39A	1.18e-07	184	56	6	2a8338e94937686a148b5433515700ca0f674058
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 ABCA13 DNAH17 LRRK2 EPHA4	1.33e-06	151	56	5	16fc903fc71e25717b9908416f0bcd29c0a65a61
ToppCell	IIH-CD8-CD4_Treg\|IIH / Condition, Cell_class and T cell subcluster	TAOK2 CUL4A ZNF343 MAGI3 ATP10A	3.14e-06	180	56	5	d1a8b25115c80e5a5bd0b8244167a98250ab9778
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 ABCA13 LRRK2 GTF2IRD1 EPHA4	3.22e-06	181	56	5	9d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 ABCA13 LRRK2 GTF2IRD1 EPHA4	3.31e-06	182	56	5	eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 ABCA13 DNAH17 LRRK2 GTF2IRD1	3.78e-06	187	56	5	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Dendritic-pDC\|lymph-node_spleen / Manually curated celltypes from each tissue	SHD SCARB1 TTC39A AR BAHCC1	3.98e-06	189	56	5	6c2ace61a7d62bcf7e76b73e2da8b722d03e713b
ToppCell	mLN-(5)_Dendritic_cell-(54)_pDC\|mLN / shred on region, Cell_type, and subtype	SHD GXYLT2 SCARB1 AR BAHCC1	5.12e-06	199	56	5	1e738219784a446ee8b0ddeb408e0050e1929e60
ToppCell	mLN-Dendritic_cell-pDC\|mLN / Region, Cell class and subclass	SHD GXYLT2 SCARB1 AR BAHCC1	5.12e-06	199	56	5	54f1abb57af7bf8a8b82a38b933f257df3b5d8df
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-AT2-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCA3 SULT1C2 STARD10 LRRK2 TTC39A	5.25e-06	200	56	5	65c83a3f6ee2a10bcb5b95076696232c6373a7b4
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-AT2-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABCA3 SULT1C2 STARD10 LRRK2 TTC39A	5.25e-06	200	56	5	40e969883bc302e8fbc6b6ab9814529dc1472902
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-AT2-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	ABCA3 SULT1C2 STARD10 LRRK2 TTC39A	5.25e-06	200	56	5	ad9cdc82a647d379abc713a56db0e11bb6494106
ToppCell	Hippocampus-Macroglia-CSF_related-CHOROID_PLEXUS-Choroid_Plexus.Ttr_(Ttr)--\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SFRP5 SULT1C2 ABCA13 F5	1.98e-05	127	56	4	ca77f85502dd66f3cb4b15cf80f755104ca1e6ff
ToppCell	Hippocampus-Macroglia-CSF_related-CHOROID_PLEXUS\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SFRP5 SULT1C2 ABCA13 F5	1.98e-05	127	56	4	25d0b28c9df2d10fbcdb0aca47b75bf5c7c9c430
ToppCell	Hippocampus-Macroglia-CSF_related-CHOROID_PLEXUS-Choroid_Plexus.Ttr_(Ttr)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SFRP5 SULT1C2 ABCA13 F5	1.98e-05	127	56	4	b27d5141e661a4c6924aa6d7c5b046f9ae49955d
ToppCell	Hippocampus-Macroglia-CSF_related-CHOROID_PLEXUS-Choroid_Plexus.Ttr_(Ttr)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SFRP5 SULT1C2 ABCA13 F5	1.98e-05	127	56	4	352d44233a93c926aeb7c5fad49965fd82b873ca
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 ABCA13 LRRK2 EPHA4	3.08e-05	142	56	4	6469cf82552b39f63e20b841c9eed50de6f58d54
ToppCell	LPS-IL1RA-Myeloid_granulocytic-Neutrophils\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABCA4 ABCA13 MR1 ATP10A	4.22e-05	154	56	4	43735f7c58cac51855ded486ee8d8729a1b9909e
ToppCell	LPS-IL1RA-Myeloid_granulocytic\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABCA4 ABCA13 MR1 ATP10A	4.22e-05	154	56	4	d55fb73461885e1e02061a344ff89624ef4de487
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABCA3 LRRK2 MAGI3 DNAH14	4.78e-05	159	56	4	e6ff9d2bce62bf9ea173af80b688eeb40fa4ea4c
ToppCell	PND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCA3 STARD10 MAGI3 EPHA4	5.14e-05	162	56	4	d0d9c18a73bc0bf4f38308ef2eee8ae20f6a7918
ToppCell	PND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCA3 STARD10 MAGI3 EPHA4	5.14e-05	162	56	4	06f5d6c0bb26fe9d5180bc2ebf2c54bf52e715f3
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	GXYLT2 DLGAP2 TRBV6-6 ATP10D	5.65e-05	166	56	4	65dafed953b01a9830b54309af75c7a561e88336
ToppCell	B_cells-pDCs\|World / Immune cells in Kidney/Urine in Lupus Nephritis	SHD SCARB1 TTC39A AR	5.92e-05	168	56	4	dc8f94424f60ab56facdcffa969e7f3466ee1b6e
ToppCell	10x5'-lymph-node_spleen-Myeloid_Dendritic-pDC\|lymph-node_spleen / Manually curated celltypes from each tissue	SHD TTC39A AR BAHCC1	5.92e-05	168	56	4	cfed36fece51871a5abbcde71f6bd5e7212357ff
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 ABCA13 DNAH17 LRRK2	6.20e-05	170	56	4	5d5f208682be21ed58320f5fc083a7898f8712da
ToppCell	5'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EECs\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A PHKA1 ABCA4 DNAH17	6.34e-05	171	56	4	dd37e1693a5cfc42e40992d504f92048a8038b52
ToppCell	mild_COVID-19-pDC\|mild_COVID-19 / disease group, cell group and cell class (v2)	SHD GXYLT2 TTC39A AR	6.94e-05	175	56	4	b87f279a7519710146c49d6acccb0adedc195965
ToppCell	B_cells-pDCs\|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis	SHD SCARB1 TTC39A AR	7.09e-05	176	56	4	ce757de9e09a225f3f96433f103f43619b0e0dda
ToppCell	Healthy/Control-pDC\|Healthy/Control / Disease group and Cell class	SHD GXYLT2 TTC39A AR	7.41e-05	178	56	4	072b346c6bbd63f00efaceda486400a669b3ec48
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 SFRP5 SULT1C2 F5	7.57e-05	179	56	4	9d7e39357b269d30ff1e8007a91f8645f3d80e73
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 SFRP5 SULT1C2 F5	7.57e-05	179	56	4	1611e11f5f74432627e2f57a27e352b1e46be618
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLGAP2 SFRP5 ECE1 F5	7.74e-05	180	56	4	0677bf4a5177d9cbc6716195bd966eeae8de2f31
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP1 FMO4 TTC39A R3HDML	7.90e-05	181	56	4	a5e770b5b5d57cbac18560828e89f7c96b687743
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP1 FMO4 TTC39A R3HDML	7.90e-05	181	56	4	504b1af1951a7a20ef5db69d84c20630ec64095b
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP1 FMO4 TTC39A R3HDML	7.90e-05	181	56	4	a55ec36d2393f7a376feb42b22aee75dfdf4c383
ToppCell	Control-Epithelial_alveolar-AT_2-AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GXYLT2 ABCA3 STARD10 TTC39A	8.07e-05	182	56	4	e97681a4102f3095d5d9e90ad70f1dc46e90983a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 ABCA13 DNAH17 LRRK2	8.25e-05	183	56	4	92fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GXYLT2 DLGAP2 SFRP5 MR1	8.42e-05	184	56	4	3da93e7d8b62463e307cc0425c47dbd3bef66799
ToppCell	Healthy_donor-pDC\|Healthy_donor / disease group, cell group and cell class (v2)	SHD SCARB1 TTC39A AR	8.60e-05	185	56	4	7fbb55cbdb39bdecb6063c8ba9776ab06c2666e8
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABCA3 ABCA13 LRRK2 DNAH14	8.78e-05	186	56	4	acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 ABCA13 LRRK2 DNAH14	8.78e-05	186	56	4	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 ABCA13 LRRK2 DNAH14	8.96e-05	187	56	4	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	Healthy_donor-pDC\|World / disease group, cell group and cell class (v2)	SHD SCARB1 TTC39A AR	8.96e-05	187	56	4	aa2cc54487d3c5045ac0c93560944c5a55878e27
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 ABCA13 LRRK2 DNAH14	9.15e-05	188	56	4	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D175\|Adult / Lineage, Cell type, age group and donor	ABCA3 ABCA13 LRRK2 DNAH14	9.15e-05	188	56	4	ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCell	Control-Epithelial_cells\|Control / group, cell type (main and fine annotations)	ABCA3 LRRK2 MAGI3 DNAH14	9.15e-05	188	56	4	707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCell	3'_v3-bone_marrow-Myeloid_Dendritic-pDC\|bone_marrow / Manually curated celltypes from each tissue	SHD SCARB1 TTC39A AR	9.53e-05	190	56	4	dde0e34f6a06cdbbb65c86472360c09f0279a572
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Dendritic\|lymph-node_spleen / Manually curated celltypes from each tissue	SHD SCARB1 TTC39A AR	9.73e-05	191	56	4	c3ff4342e0eea1e1f071b1fbca14a6dd4df0c696
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SHD SFRP1 ABCA4 ABCA13	9.73e-05	191	56	4	5a5b5402a077b3189ca156f2bac5f47ad780aebf
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SHD SFRP1 ABCA4 ABCA13	9.73e-05	191	56	4	78bcce497920cc5b3bef083eab50deb1cc82cd2e
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABCA3 LRRK2 MAGI3 DNAH14	9.73e-05	191	56	4	ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SHD SFRP1 ABCA4 ABCA13	9.73e-05	191	56	4	297bc79adc5fef211497819b4861b52cd26ac754
ToppCell	Children_(3_yrs)-Epithelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ABCA3 LRRK2 MAGI3 DNAH14	9.73e-05	191	56	4	e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	LIMK2 LRRK2 ECE1 F5	9.73e-05	191	56	4	b9b091d6b352d5128bb864ff52d2e5fb3387b766
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SHD SFRP1 ABCA4 ABCA13	9.73e-05	191	56	4	e1ec165ba6578cefd88895e7e183190e79f733a4
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	ABCA3 LRRK2 MAGI3 DNAH14	9.73e-05	191	56	4	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	ABCA3 LRRK2 MAGI3 DNAH14	9.92e-05	192	56	4	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	Epithelial\|World / Lineage, Cell type, age group and donor	ABCA3 LRRK2 MAGI3 DNAH14	9.92e-05	192	56	4	499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABCA3 LRRK2 MAGI3 DNAH14	9.92e-05	192	56	4	fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCell	human_hepatoblastoma-Tumor_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	SCARB1 MAGI3 F5 DNAH14	1.01e-04	193	56	4	503a979328c68b096680b71359a26f02fafdff35
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_alveolar-Dividing_AT2\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA3 STARD10 LRRK2 TOP2A	1.01e-04	193	56	4	44839a606ae2f8e37421bda46d588189e1c943d2
ToppCell	Fetal_29-31_weeks-Epithelial\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABCA3 LRRK2 MAGI3 DNAH14	1.01e-04	193	56	4	a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCell	nucseq-Epithelial-Epithelial_Alveolar\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ABCA3 LRRK2 MAGI3 DNAH14	1.03e-04	194	56	4	53f3e49e91b1096f3226010e2de767efb490dfe4
ToppCell	facs-Thymus-nan-3m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MR1 MAGI3 GTF2IRD1 ATP10A	1.05e-04	195	56	4	79114b3c78cc15c413bb58f0673e7215b784a9b6
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CACNA1A ABCA13 F5 DNAH14	1.05e-04	195	56	4	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	nucseq-Epithelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ABCA3 LRRK2 MAGI3 DNAH14	1.05e-04	195	56	4	9406866f99555198a9be311fbd65751b70f35446
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CACNA1A ABCA13 F5 DNAH14	1.05e-04	195	56	4	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SULT1C2 LRRK2 GTF2IRD1 DNAH14	1.07e-04	196	56	4	6ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA3 SULT1C2 LRRK2 TTC39A	1.07e-04	196	56	4	82b117be41f2e7d677a42d2a5198726eeccb16d0
ToppCell	myeloid-pro-pDC\|myeloid / Lineage and Cell class	SHD GXYLT2 TOP2A BAHCC1	1.07e-04	196	56	4	70daf4fabb68aecc5cc9f03d6f6495dd29b74a16
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_2-AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ABCA3 STARD10 LRRK2 TTC39A	1.10e-04	197	56	4	ad6f047d003c08413264f39a30ba0f7639a257cd
ToppCell	myeloid-pro-pDC\|World / Lineage and Cell class	SHD GXYLT2 TOP2A BAHCC1	1.10e-04	197	56	4	8918ee006b16f6b86ed33ce1dd5c0f01f51f88f5
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_only / Treatment groups by lineage, cell group, cell type	ABCA3 ABCA4 SCARB1 LRRK2	1.10e-04	197	56	4	6b6504c47c309bac4f790e2f372d454bbdea49e8
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ABCA3 STARD10 LRRK2 TTC39A	1.10e-04	197	56	4	1638959d7aecb9fc5285eb7e4a3103ca437989e2
ToppCell	Control_saline-Epithelial_alveolar-AT_2-AT2\|Control_saline / Treatment groups by lineage, cell group, cell type	GXYLT2 ABCA3 STARD10 TTC39A	1.10e-04	197	56	4	f870a26f322668781e3d2832c5d9ef2c7c91011f
ToppCell	LPS_only-Epithelial_alveolar-AT_2-AT2\|LPS_only / Treatment groups by lineage, cell group, cell type	GXYLT2 ABCA3 STARD10 LRRK2	1.12e-04	198	56	4	6b6572deeca98ccb015f2aa3c5ce27de44445f74
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA3 LRRK2 MAGI3 DNAH14	1.14e-04	199	56	4	725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_alveolar-AT2\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA3 STARD10 LRRK2 TTC39A	1.14e-04	199	56	4	fa5ddba3ac1ebe712cd4cdc3f20339f7c715d039
ToppCell	Biopsy_IPF-Epithelial-AT2\|Biopsy_IPF / Sample group, Lineage and Cell type	ABCA3 SFRP5 STARD10 LRRK2	1.14e-04	199	56	4	c841d475703d3489161fb7904526bd7563d5fb0f
ToppCell	LPS_only-Epithelial_alveolar-AT_1-2_Progenitor-Progenitor_AT1-AT2\|LPS_only / Treatment groups by lineage, cell group, cell type	GXYLT2 ABCA3 STARD10 LRRK2	1.14e-04	199	56	4	0447f8f53389fe7c6ddc04a97d86e74122ea16f4
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	SULT1C2 LCT F5	1.16e-04	75	56	3	3167beedef7304697e9577270cdeacfc9743cee1
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	SULT1C2 LCT F5	1.16e-04	75	56	3	70c346f92a9ac7e33fc1b9dee1dca0bf9ae0a38c
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	SULT1C2 LCT F5	1.16e-04	75	56	3	26d6e54ed0a6c3ff57f6269c460177bc7b8bf979
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-AT2-2\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	ABCA3 STARD10 LRRK2 TTC39A	1.16e-04	200	56	4	35c05cae30cd6b323d2662f1396ddeab08bc75fc
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-AT2-2-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCA3 STARD10 LRRK2 TTC39A	1.16e-04	200	56	4	3c251ad03fbbdae91dfd9037880ba43adbb03807
ToppCell	Lung_Parenchyma-Control-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABCA3 STARD10 LRRK2 TTC39A	1.16e-04	200	56	4	c2bde99b3bc7a8740441c1a0c1394892b940b857
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-AT2-2\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABCA3 STARD10 LRRK2 TTC39A	1.16e-04	200	56	4	c905451425d1c24773bb0ca69bcf0309b277d2f1
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	ABCA3 STARD10 LRRK2 TTC39A	1.16e-04	200	56	4	9970e9bde6aa2ff3aef60dcb065ff15b7463e147
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCA3 STARD10 LRRK2 MAGI3	1.16e-04	200	56	4	eb44d1f80ecaac3a022cd04ab16dc36151e45488
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABCA3 STARD10 LRRK2 TTC39A	1.16e-04	200	56	4	3ff9abd5e07780a59d5571da906fa15f00a1d5c2
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABCA3 STARD10 LRRK2 MAGI3	1.16e-04	200	56	4	acc771a902cf2f060c3eb9aedb72a256f5778a6c
ToppCell	Parenchyma_COVID-19-Epithelial-TX-AT2-2\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	ABCA3 STARD10 LRRK2 MAGI3	1.16e-04	200	56	4	ceb613ac6cdf0e3e6bb3f04d89034e18a524cefb
ToppCell	(54)_pDC\|World / shred on Cell_type and subtype	SHD GXYLT2 AR BAHCC1	1.23e-04	203	56	4	b8ba3e51770ff7b45cd02472f3e63aa4d5816f6f
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Cfh_(Cfh)--\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	FMO4 SULT1C2 F5	1.86e-04	88	56	3	5f774a85415d3cf163046f1154a82f749bf628fe
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Cfh_(Cfh)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	FMO4 SULT1C2 F5	1.86e-04	88	56	3	5582666aed9c1f465264f18898783872b662400d
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Cfh_(Cfh)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	FMO4 SULT1C2 F5	1.86e-04	88	56	3	f59eeaba4a3c5ef03f741ed6a31fe88f57651374
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)\|Thalamus / BrainAtlas - Mouse McCarroll V32	GXYLT2 ABCA4 FMO4	2.12e-04	92	56	3	bbaf5a131f860198840e34843b7c841bcc98d9c4
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)-\|Thalamus / BrainAtlas - Mouse McCarroll V32	GXYLT2 ABCA4 FMO4	2.12e-04	92	56	3	e6aa2b8ca9235a7291ee41d976b886fec185835d
Disease	Williams-Beuren syndrome (implicated_via_orthology)	LIMK1 LIMK2 GTF2IRD1	2.90e-06	15	56	3	DOID:1928 (implicated_via_orthology)
Disease	progressive familial intrahepatic cholestasis (implicated_via_orthology)	ATP10A ATP10D	1.06e-05	3	56	2	DOID:0070221 (implicated_via_orthology)
Disease	alpha-linolenic acid measurement	SFRP5 LCT DAGLA	1.45e-05	25	56	3	EFO_0007759
Disease	lysophosphatidylethanolamine 20:4 measurement	SFRP1 MAGI3 DAGLA	2.28e-05	29	56	3	EFO_0010370
Disease	Williams Syndrome	LIMK1 GTF2IRD1	9.83e-05	8	56	2	C0175702
Disease	temporomandibular joint disorder	SFRP1 BAHCC1	1.58e-04	10	56	2	EFO_0005279
Disease	Colorectal Neoplasms	ABCA3 SFRP1 ABCA4 SFRP5 ABCA13	1.82e-04	277	56	5	C0009404
Disease	autism spectrum disorder (implicated_via_orthology)	TAOK2 ABCA3 CNTNAP1 TAOK1	2.02e-04	152	56	4	DOID:0060041 (implicated_via_orthology)
Disease	Colorectal Carcinoma	ABCA3 SFRP1 ABCA4 SFRP5 ABCA13 CPO F5	3.53e-04	702	56	7	C0009402
Disease	pentachlorophenol measurement	DLGAP2 SFRP1 F5	3.67e-04	73	56	3	EFO_0022071
Disease	parathion measurement	DLGAP2 SFRP1 F5	3.67e-04	73	56	3	EFO_0022070
Disease	potassium chromate measurement	DLGAP2 SFRP1 F5	3.67e-04	73	56	3	EFO_0022072
Disease	mercuric chloride measurement	DLGAP2 SFRP1 F5	3.67e-04	73	56	3	EFO_0022068
Disease	heptachlor epoxide measurement	DLGAP2 SFRP1 F5	3.67e-04	73	56	3	EFO_0022067
Disease	methoxychlor measurement	DLGAP2 SFRP1 F5	3.67e-04	73	56	3	EFO_0022069
Disease	4,6-dinitro-o-cresol measurement	DLGAP2 SFRP1 F5	3.67e-04	73	56	3	EFO_0022053
Disease	2,4,5-trichlorophenol measurement	DLGAP2 SFRP1 F5	3.67e-04	73	56	3	EFO_0022052
Disease	azinphos methyl measurement	DLGAP2 SFRP1 F5	3.67e-04	73	56	3	EFO_0022055
Disease	aldrin measurement	DLGAP2 SFRP1 F5	3.67e-04	73	56	3	EFO_0022054
Disease	dicofol measurement	DLGAP2 SFRP1 F5	3.67e-04	73	56	3	EFO_0022060
Disease	disulfoton measurement	DLGAP2 SFRP1 F5	3.67e-04	73	56	3	EFO_0022062
Disease	dieldrin measurement	DLGAP2 SFRP1 F5	3.67e-04	73	56	3	EFO_0022061
Disease	endrin measurement	DLGAP2 SFRP1 F5	3.67e-04	73	56	3	EFO_0022064
Disease	endosulfan measurement	DLGAP2 SFRP1 F5	3.67e-04	73	56	3	EFO_0022063
Disease	heptachlor measurement	DLGAP2 SFRP1 F5	3.67e-04	73	56	3	EFO_0022066
Disease	ethion measurement	DLGAP2 SFRP1 F5	3.67e-04	73	56	3	EFO_0022065
Disease	chlorpyrifos measurement	DLGAP2 SFRP1 F5	3.67e-04	73	56	3	EFO_0022057
Disease	cadmium chloride measurement	DLGAP2 SFRP1 F5	3.67e-04	73	56	3	EFO_0022056
Disease	diazinon measurement	DLGAP2 SFRP1 F5	3.67e-04	73	56	3	EFO_0022059
Disease	dibutyl phthalate measurement	DLGAP2 SFRP1 F5	3.67e-04	73	56	3	EFO_0022058
Disease	environmental exposure measurement	DLGAP2 SFRP1 F5	3.67e-04	73	56	3	EFO_0008360
Disease	DDT metabolite measurement	DLGAP2 SFRP1 F5	3.81e-04	74	56	3	EFO_0007886
Disease	Blood Coagulation Disorders	F5 GGCX	4.17e-04	16	56	2	C0005779
Disease	central nervous system disease (implicated_via_orthology)	TAOK2 TAOK1	4.17e-04	16	56	2	DOID:331 (implicated_via_orthology)
Disease	methylcobalamin deficiency type cblE, brain serotonin transporter measurement	LIMK2 EPHA4	4.17e-04	16	56	2	EFO_0004569, MONDO_0009354
Disease	sensorineural hearing loss (implicated_via_orthology)	SCARB1 DNAH17	5.93e-04	19	56	2	DOID:10003 (implicated_via_orthology)
Disease	blood cobalt measurement	DLGAP2 SFRP1 F5	9.46e-04	101	56	3	EFO_0007577
Disease	D dimer measurement	ABCA4 F5	1.49e-03	30	56	2	EFO_0004507
Disease	blood nickel measurement	DLGAP2 SFRP1 F5	1.55e-03	120	56	3	EFO_0007583

Protein segments in the cluster

Peptide	Gene	Start	Entry
MYWYRQDPGMGLKLI	TRBV6-6	51	A0A0A6YYG2
AAWGRMPYLDMYQML	CACNA1A	1841	O00555
ADVMDQASLWPPMYG	BAHCC1	891	Q9P281
MPLQTYIWMEYDQPL	CNTNAP1	901	P78357
GWAVIPMMYPASFLF	ABCA4	1771	P78363
LLYGWAIIPLMYLMN	ABCA3	1186	Q99758
FGYATLPWMYLMSRI	ABCA13	4546	Q86UQ4
MPRPTSQDLAGYWDM	DLGAP2	936	Q9P1A6
MPPTYYDAWSLRKAM	ANXA7	256	P20073
SYNIYHPMGEIYEWM	CPO	46	Q8IVL8
PYWTMQALLGDPVFY	ATP10A	1261	O60312
PYWIMQEHMLDPVFY	ATP10D	1286	Q9P241
APYLKSLMGYWLMAQ	LTN1	141	O94822
MMEFLIEYGPAQLYW	DCAF1	571	Q9Y4B6
PKNWEMAYTDTGMIY	MAGI3	296	Q5TCQ9
LLGMPLEVYEMWRNY	NMUR2	96	Q9GZQ4
YWMAPEMLNGKSYDE	LIMK2	511	P53671
DILYMLYTMKGPDWN	PHKA1	781	P46020
GIVMWEVMSYGERPY	EPHA4	811	P54764
LGRSSDWGYPYNMMV	FMO4	221	P31512
SMIPTGLAWEDMLYP	GXYLT2	286	A0PJZ3
MTFNEPMYLAWLGYG	LCT	1061	P09848
IIRLYEMPYFPMGFW	LRRK2	1691	Q5S007
EMPYFPMGFWSRLIN	LRRK2	1696	Q5S007
PWMDSYSGPYGDMRL	AR	526	P10275
LPEWSEGYPFYMAMG	POGK	161	Q9P215
YNPNLATYMKPEMWG	EIF3CL	386	B5ME19
AYPSMMGLAAWYADL	DNAH17	4286	Q9UFH2
NILTMGYWPTYTPME	CUL4A	526	Q13619
PESGELMMSLLWYYR	BAHD1	656	Q8TBE0
AMVYMDPVDLGWEPY	DNAH14	1631	Q0VDD8
AAYGWPMYLMRKPAC	DAGLA	301	Q9Y4D2
DQWSMTPPMVNAYYS	ECE1	556	P42892
LVQWPMYMVDYAGLN	GTF2IRD1	936	Q9UHL9
SVYPPAANMEYMVWD	R3HDML	76	Q9H3Y0
GFYPPEIYMTWMKNG	MR1	226	Q95460
WSLGVIMYEMLIGYP	STK38	306	Q15208
DGYMEPYDAQWVMSE	SHD	121	Q96IW2
WLPMGADYIIMNYSV	STARD10	136	Q9Y365
APLMEAYGFPWPEML	SFRP5	136	Q5T4F7
MIYSLPGLKMYEQEW	F5	1811	P12259
PLMWQLYPEERYMDN	MTCP1	66	P56278
MWPPFMTPESSLEFY	SCARB1	261	Q8WTV0
PYWMAPEVILAMDEG	TAOK1	186	Q7L7X3
PYWMAPEVILAMDEG	TAOK2	186	Q9UL54
EPVMQFFGFYWPEML	SFRP1	141	Q8N474
MMLPYPSALGDQYWE	ZNF343	1	Q6P1L6
PLDWMYLVYTIMFLG	GGCX	111	P38435
FKESWPQYSQMYPGM	UBTFL1	111	P0CB47
MNHMLPDPGTWEEYF	SULT1C2	146	O00338
SGPTFNYLLDMPLWY	TOP2A	1121	P11388
MLFEWIYPSYMPILQ	XPO7	741	Q9UIA9
RPMYPILRYMWGTDT	UBE4A	746	Q14139
MMILVFWSNYPYEPV	WHAMMP3	1	Q1A5X7
YLGPAVLMQAYRWMI	SDHB	206	P21912
PALEMMYIWNGYAVI	TTC39A	456	Q5SRH9
YDWLYLGFMAMLPLV	JKAMP	56	Q9P055
RYTVVGNPYWMAPEM	LIMK1	506	P53667