Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	phosphatase activity	IMPA2 NT5E PPM1D PLPP7 PFKFB4 NT5DC3 SACM1L PPP4C PPP6C PTPRM TNS3	5.92e-07	287	111	11	GO:0016791
GeneOntologyMolecularFunction	phosphoric ester hydrolase activity	IMPA2 NT5E PPM1D PLPP7 PFKFB4 NT5DC3 SACM1L PPP4C PPP6C PTPRM TNS3	1.03e-05	386	111	11	GO:0042578
GeneOntologyMolecularFunction	calcium ion binding	FAT4 AOC1 PCDHGA9 PCDHGA6 PCDHGA5 ASAH2 PCDHGA2 PCDHGA1 LRP1B PCDHGA12 JAG1 PCDH9 ASAH2B ATP5F1B	7.01e-05	749	111	14	GO:0005509
GeneOntologyMolecularFunction	hydrolase activity, acting on ester bonds	AARS1 IMPA2 NT5E PPM1D PLPP7 PFKFB4 DTD2 NT5DC3 SACM1L PPP4C PPP6C PTPRM PNPLA7 TNS3	1.54e-04	807	111	14	GO:0016788
GeneOntologyMolecularFunction	adenine transmembrane transporter activity	SLC25A4 SLC25A5	3.03e-04	5	111	2	GO:0015207
GeneOntologyMolecularFunction	ATP:ADP antiporter activity	SLC25A4 SLC25A5	3.03e-04	5	111	2	GO:0005471
GeneOntologyMolecularFunction	oxidative phosphorylation uncoupler activity	SLC25A4 SLC25A5	3.03e-04	5	111	2	GO:0017077
GeneOntologyMolecularFunction	phosphofructokinase activity	PFKFB4 PFKM	6.32e-04	7	111	2	GO:0008443
GeneOntologyMolecularFunction	N-acylsphingosine amidohydrolase activity	ASAH2 ASAH2B	6.32e-04	7	111	2	GO:0017040
GeneOntologyBiologicalProcess	homophilic cell adhesion via plasma membrane adhesion molecules	FAT4 PCDHGA9 PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1 PTPRM PCDHGA12 PCDH9	7.21e-07	187	110	9	GO:0007156
GeneOntologyCellularComponent	pore complex	SLC25A4 SLC25A5 C5 VDAC2	1.03e-05	26	111	4	GO:0046930
Domain	Cadherin	FAT4 PCDHGA9 PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1 KIAA0319 PCDHGA12 PCDH9	3.21e-08	118	110	9	IPR002126
Domain	Cadherin_tail	PCDHGA9 PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1 PCDHGA12	7.29e-08	37	110	6	PF15974
Domain	Cadherin_CBD	PCDHGA9 PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1 PCDHGA12	7.29e-08	37	110	6	IPR031904
Domain	Cadherin_2	PCDHGA9 PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1 PCDHGA12 PCDH9	1.07e-07	65	110	7	PF08266
Domain	Cadherin_N	PCDHGA9 PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1 PCDHGA12 PCDH9	1.07e-07	65	110	7	IPR013164
Domain	Cadherin_C	PCDHGA9 PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1 PCDHGA12	1.61e-07	42	110	6	IPR032455
Domain	Cadherin_C_2	PCDHGA9 PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1 PCDHGA12	1.61e-07	42	110	6	PF16492
Domain	Cadherin_CS	FAT4 PCDHGA9 PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1 PCDHGA12 PCDH9	2.60e-07	109	110	8	IPR020894
Domain	CADHERIN_1	FAT4 PCDHGA9 PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1 PCDHGA12 PCDH9	3.43e-07	113	110	8	PS00232
Domain	Cadherin	FAT4 PCDHGA9 PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1 PCDHGA12 PCDH9	3.43e-07	113	110	8	PF00028
Domain	CADHERIN_2	FAT4 PCDHGA9 PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1 PCDHGA12 PCDH9	3.67e-07	114	110	8	PS50268
Domain	-	FAT4 PCDHGA9 PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1 PCDHGA12 PCDH9	3.67e-07	114	110	8	2.60.40.60
Domain	CA	FAT4 PCDHGA9 PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1 PCDHGA12 PCDH9	3.93e-07	115	110	8	SM00112
Domain	Cadherin-like	FAT4 PCDHGA9 PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1 PCDHGA12 PCDH9	4.20e-07	116	110	8	IPR015919
Domain	Ceramidse_alk_C	ASAH2 ASAH2B	3.44e-05	2	110	2	PF17048
Domain	NEUT/ALK_ceramidase_C	ASAH2 ASAH2B	3.44e-05	2	110	2	IPR031331
Domain	Ceramidase_alk	ASAH2 ASAH2B	3.44e-05	2	110	2	IPR006823
Domain	Myosin_S1_N	MYH10 MYH11	3.40e-04	5	110	2	IPR008989
Domain	HELP	EML6 EML5	5.08e-04	6	110	2	PF03451
Domain	Haem_d1	STXBP5L EML6	5.08e-04	6	110	2	IPR011048
Domain	HELP	EML6 EML5	5.08e-04	6	110	2	IPR005108
Domain	Metallophos	NT5E PPP4C PPP6C	5.85e-04	28	110	3	PF00149
Domain	Calcineurin-like_PHP_ApaH	NT5E PPP4C PPP6C	5.85e-04	28	110	3	IPR004843
Domain	Metallo-depent_PP-like	NT5E PPP4C PPP6C	7.19e-04	30	110	3	IPR029052
Domain	-	NT5E PPP4C PPP6C	7.19e-04	30	110	3	3.60.21.10
Domain	Plexin_cytopl	PLXNA1 PLXNA2	1.20e-03	9	110	2	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXNA1 PLXNA2	1.20e-03	9	110	2	IPR013548
Domain	Plexin	PLXNA1 PLXNA2	1.20e-03	9	110	2	IPR031148
Domain	PKD/Chitinase_dom	SORCS1 KIAA0319	1.20e-03	9	110	2	IPR022409
Domain	PKD	SORCS1 KIAA0319	1.20e-03	9	110	2	SM00089
Domain	Myosin_head_motor_dom	MYH10 MYH11 MYO15A	1.44e-03	38	110	3	IPR001609
Domain	MYOSIN_MOTOR	MYH10 MYH11 MYO15A	1.44e-03	38	110	3	PS51456
Domain	Myosin_head	MYH10 MYH11 MYO15A	1.44e-03	38	110	3	PF00063
Domain	MYSc	MYH10 MYH11 MYO15A	1.44e-03	38	110	3	SM00242
Domain	PKD	SORCS1 KIAA0319	1.83e-03	11	110	2	PS50093
Domain	PKD_dom	SORCS1 KIAA0319	1.83e-03	11	110	2	IPR000601
Domain	-	SORCS1 KIAA0319	1.83e-03	11	110	2	2.60.40.670
Domain	Mit_uncoupling	SLC25A4 SLC25A5	2.18e-03	12	110	2	IPR002030
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01006	SLC25A4 SLC25A5 VDAC2	1.98e-05	10	79	3	M47694
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY	SLC25A4 SLC25A5 VDAC2	4.65e-05	13	79	3	M47696
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_SIGMAR1_TO_CA2_APOPTOTIC_PATHWAY	SLC25A4 SLC25A5 VDAC2	4.65e-05	13	79	3	M47751
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_VGCC_CA2_APOPTOTIC_PATHWAY	SLC25A4 SLC25A5 VDAC2	4.65e-05	13	79	3	M47703
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01004	SLC25A4 SLC25A5 VDAC2	5.90e-05	14	79	3	M47692
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_TRANSPORT_OF_CALCIUM	SLC25A4 SLC25A5 VDAC2	7.34e-05	15	79	3	M47691
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY	SLC25A4 SLC25A5 VDAC2	9.00e-05	16	79	3	M47695
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABBERANT_ATXN2_3_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY	SLC25A4 SLC25A5 VDAC2	1.30e-04	18	79	3	M47659
Pathway	KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_TRANSPORT_OF_CALCIUM	SLC25A4 SLC25A5 VDAC2	1.30e-04	18	79	3	M47761
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_TRANSPORT_OF_CALCIUM	SLC25A4 SLC25A5 VDAC2	1.54e-04	19	79	3	M47677
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_ROCKS	MYH10 MYH11 PPP1R12B	1.54e-04	19	79	3	M27493
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_CIT	MYH10 MYH11 PPP1R12B	1.54e-04	19	79	3	M27489
Pathway	KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY	SLC25A4 SLC25A5 VDAC2	1.54e-04	19	79	3	M47760
Pathway	KEGG_MEDICUS_REFERENCE_MACHR_CA2_APOPTOTIC_PATHWAY	SLC25A4 SLC25A5 VDAC2	1.80e-04	20	79	3	M47688
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MACHR_CA2_APOPTOTIC_PATHWAY	SLC25A4 SLC25A5 VDAC2	2.09e-04	21	79	3	M47689
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_PAKS	MYH10 MYH11 PPP1R12B	2.09e-04	21	79	3	M27494
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY	SLC25A4 SLC25A5 VDAC2	2.42e-04	22	79	3	M47690
Pathway	KEGG_MEDICUS_REFERENCE_MGLUR5_CA2_APOPTOTIC_PATHWAY	SLC25A4 SLC25A5 VDAC2	2.42e-04	22	79	3	M47675
Pathway	KEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY	SLC25A4 SLC25A5 VDAC2	2.77e-04	23	79	3	M47666
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY	SLC25A4 SLC25A5 VDAC2	2.77e-04	23	79	3	M47676
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_PAKS	MYH10 MYH11 PPP1R12B	2.77e-04	23	79	3	MM15222
Pathway	REACTOME_SEMAPHORIN_INTERACTIONS	MYH10 MYH11 PLXNA1 PLXNA2	4.50e-04	64	79	4	M7923
Pathway	REACTOME_SIGNALING_BY_MET	COL11A1 ITGA2 LRIG1 TNS3	5.36e-04	67	79	4	MM15345
Pathway	REACTOME_MET_PROMOTES_CELL_MOTILITY	COL11A1 ITGA2 TNS3	6.17e-04	30	79	3	MM15517
Pathway	KEGG_FRUCTOSE_AND_MANNOSE_METABOLISM	PFKFB4 PFKM GMPPA	8.94e-04	34	79	3	M15898
Pathway	REACTOME_SIGNALING_BY_MET	COL11A1 ITGA2 LRIG1 TNS3	9.98e-04	79	79	4	M27643
Pathway	REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION	PLXNA1 PLXNA2	1.09e-03	9	79	2	MM15030
Pathway	REACTOME_MET_PROMOTES_CELL_MOTILITY	COL11A1 ITGA2 TNS3	1.55e-03	41	79	3	M27778
Pathway	REACTOME_TRANSPORT_OF_NUCLEOSIDES_AND_FREE_PURINE_AND_PYRIMIDINE_BASES_ACROSS_THE_PLASMA_MEMBRANE	SLC25A4 SLC25A5	1.65e-03	11	79	2	MM15471
Pubmed	Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.	PCDHGA9 PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1 PCDHGA12 PCDH9	4.20e-09	74	111	7	10817752
Pubmed	Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.	PCDHGA9 PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1 PCDHGA12 PCDH9	5.57e-09	77	111	7	10835267
Pubmed	Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.	PCDHGA9 PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1 PCDHGA12 PCDH9	7.30e-09	80	111	7	10716726
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	RPL21 AARS1 MYH10 MYH11 ITGA2 MPRIP SACM1L SORCS1 GMPPA FBXO21 ATP2B4 TNS3 VDAC2 ATP5F1B	2.07e-08	647	111	14	26618866
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	RPL21 MYH10 MYH11 RAP1GAP SLC25A4 SLC25A5 RTCB PPP1R12B ZNFX1 ITGA2 PFKM NT5DC3 MPRIP SACM1L SF3B3 LRIG1 ATP2B4 PRRC2B VDAC2 ATP5F1B	2.55e-08	1431	111	20	37142655
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	RPL21 MYH10 MYH11 ABI3BP SLC25A4 SLC25A5 PCDHGA9 PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1 PPP1R12B EML6 PFKM RBM22 SF3B3 PCDHGA12 PLXNA2 PRRC2B ATP5F1B	2.90e-08	1442	111	20	35575683
Pubmed	Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.	PCDHGA9 PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1 PCDHGA12	8.59e-08	68	111	6	11230163
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	RPL21 MYH10 IMPA2 SLC25A5 RTCB NT5E PPP1R12B PFKM MPRIP SACM1L RBM22 SF3B3 PPP6C GMPPA TNS3 VDAC2 ATP5F1B ADSS1	8.63e-08	1247	111	18	27684187
Pubmed	A striking organization of a large family of human neural cadherin-like cell adhesion genes.	PCDHGA9 PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1 PCDHGA12	1.21e-07	72	111	6	10380929
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	COL6A2 AARS1 SLC25A4 SLC25A5 RTCB CTSC CHD8 PFKM NT5DC3 SACM1L SLC30A7 SF3B3 PPP4C LRIG1 PNPLA7 PLXNA1 VDAC2 ATP5F1B	7.90e-07	1451	111	18	30550785
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	RPL21 MYH10 MYH11 COL11A1 SLC25A5 RTCB CTSC MPRIP PPP6C C5 HARS1 NMT1 FBXO21 ATP2B4 PRRC2B VDAC2 ATP5F1B	1.67e-06	1371	111	17	36244648
Pubmed	TSPO ligands stimulate ZnPPIX transport and ROS accumulation leading to the inhibition of P. falciparum growth in human blood.	SLC25A4 SLC25A5 VDAC2	1.75e-06	8	111	3	27641616
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	AARS1 MYH10 MYH11 SLC25A5 RTCB CHD8 SF3B3 MOV10L1 HARS1 MYO15A NMT1 VDAC2 ATP5F1B	1.91e-06	807	111	13	30575818
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	RPL21 USP36 AARS1 MYH10 TENT4B SLC25A5 RTCB PFKM SACM1L RBM22 SF3B3 KCTD16 CSTB HARS1 PLXNA1 VDAC2 ATP5F1B	2.80e-06	1425	111	17	30948266
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	RPL21 MYH10 MYH11 SLC25A4 SLC25A5 RTCB PFKM SF3B3 CSTB HARS1 ATP2B4 VDAC2 ATP5F1B	3.23e-06	847	111	13	35235311
Pubmed	Interactome of the Autoimmune Risk Protein ANKRD55.	AARS1 MYH10 SLC25A5 RTCB SF3B3 VDAC2 ATP5F1B	3.47e-06	197	111	7	31620119
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	RPL21 USP36 AARS1 MYH10 SLC25A5 RTCB CHD8 PFKM MPRIP RBM22 GTF2H4 SF3B3 PPP6C TNS3 VDAC2 ATP5F1B	6.33e-06	1353	111	16	29467282
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	RPL21 AARS1 MYH10 SLC25A5 RTCB TM9SF4 PFKM SACM1L SF3B3 PRKAG1 CSTB NMT1 PRRC2B TNS3 VDAC2 ATP5F1B	7.20e-06	1367	111	16	32687490
Pubmed	Purification and characterization of a neutral ceramidase from mouse liver. A single protein catalyzes the reversible reaction in which ceramide is both hydrolyzed and synthesized.	ASAH2 ASAH2B	1.01e-05	2	111	2	10652340
Pubmed	Neutral ceramidase gene: role in regulating ceramide-induced apoptosis.	ASAH2 ASAH2B	1.01e-05	2	111	2	14557071
Pubmed	Plexin/neuropilin complexes mediate repulsion by the axonal guidance signal semaphorin 3A.	PLXNA1 PLXNA2	1.01e-05	2	111	2	10781943
Pubmed	Genomic structure and promoter analysis of the mouse neutral ceramidase gene.	ASAH2 ASAH2B	1.01e-05	2	111	2	12435403
Pubmed	Constriction velocities of renal afferent and efferent arterioles of mice are not related to SMB expression.	MYH10 MYH11	1.01e-05	2	111	2	16316347
Pubmed	The structure of the human betaII-tryptase tetramer: fo(u)r better or worse.	TPSAB1 TPSB2	1.01e-05	2	111	2	10500112
Pubmed	Purification, characterization, molecular cloning, and subcellular distribution of neutral ceramidase of rat kidney.	ASAH2 ASAH2B	1.01e-05	2	111	2	11328816
Pubmed	Neutral ceramidase-dependent regulation of macrophage metabolism directs intestinal immune homeostasis and controls enteric infection.	ASAH2 ASAH2B	1.01e-05	2	111	2	35354041
Pubmed	Characterization of a tryptase mRNA expressed in the human basophil cell line KU812.	TPSAB1 TPSB2	1.01e-05	2	111	2	8434231
Pubmed	Involvement of neutral ceramidase in ceramide metabolism at the plasma membrane and in extracellular milieu.	ASAH2 ASAH2B	1.01e-05	2	111	2	16126722
Pubmed	Downregulation of neutral ceramidase by gemcitabine: Implications for cell cycle regulation.	ASAH2 ASAH2B	1.01e-05	2	111	2	19345744
Pubmed	Lactosylceramide contributes to mitochondrial dysfunction in diabetes.	ASAH2 ASAH2B	1.01e-05	2	111	2	26900161
Pubmed	Cloning and characterization of a second complementary DNA for human tryptase.	TPSAB1 TPSB2	1.01e-05	2	111	2	2203827
Pubmed	Loss of neutral ceramidase increases inflammation in a mouse model of inflammatory bowel disease.	ASAH2 ASAH2B	1.01e-05	2	111	2	22940715
Pubmed	Essential roles of neutral ceramidase and sphingosine in mitochondrial dysfunction due to traumatic brain injury.	ASAH2 ASAH2B	1.01e-05	2	111	2	24659784
Pubmed	A novel gene derived from a segmental duplication shows perturbed expression in Alzheimer's disease.	ASAH2 ASAH2B	1.01e-05	2	111	2	17334805
Pubmed	Loss of neutral ceramidase protects cells from nutrient- and energy -deprivation-induced cell death.	ASAH2 ASAH2B	1.01e-05	2	111	2	26747710
Pubmed	Characterization of two highly polymorphic human tryptase loci and comparison with a newly discovered monkey tryptase ortholog.	TPSAB1 TPSB2	1.01e-05	2	111	2	10898108
Pubmed	Novel pathway of ceramide production in mitochondria: thioesterase and neutral ceramidase produce ceramide from sphingosine and acyl-CoA.	ASAH2 ASAH2B	1.01e-05	2	111	2	21613224
Pubmed	The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore.	SLC25A4 SLC25A5	1.01e-05	2	111	2	14749836
Pubmed	T cells, mast cells and microvascular density in diffuse large B cell lymphoma.	TPSAB1 CD3G	1.01e-05	2	111	2	25957593
Pubmed	Deficiency in the mouse mitochondrial adenine nucleotide translocator isoform 2 gene is associated with cardiac noncompaction.	SLC25A4 SLC25A5	1.01e-05	2	111	2	27048932
Pubmed	[Expressions of integrinalpha2beta1 and CD133 in benign prostatic hyperplasia complicated by prostatitis and their significance].	ITGA2 PROM1	1.01e-05	2	111	2	22049795
Pubmed	Molecular cloning of the full-length cDNA encoding mouse neutral ceramidase. A novel but highly conserved gene family of neutral/alkaline ceramidases.	ASAH2 ASAH2B	1.01e-05	2	111	2	10753931
Pubmed	Human beta-tryptase is a ring-like tetramer with active sites facing a central pore.	TPSAB1 TPSB2	1.01e-05	2	111	2	9521329
Pubmed	Myosin heavy chain gene expression in normal and hyperplastic human prostate tissue.	MYH10 MYH11	1.01e-05	2	111	2	10906735
Pubmed	Human mast cell tryptase: multiple cDNAs and genes reveal a multigene serine protease family.	TPSAB1 TPSB2	1.01e-05	2	111	2	2187193
Pubmed	Structural requirements and mechanism for heparin-dependent activation and tetramerization of human betaI- and betaII-tryptase.	TPSAB1 TPSB2	1.01e-05	2	111	2	15567416
Pubmed	Neutral ceramidase encoded by the Asah2 gene is essential for the intestinal degradation of sphingolipids.	ASAH2 ASAH2B	1.01e-05	2	111	2	16380386
Pubmed	Human tryptases alpha and beta/II are functionally distinct due, in part, to a single amino acid difference in one of the surface loops that forms the substrate-binding cleft.	TPSAB1 TPSB2	1.01e-05	2	111	2	10391906
Pubmed	The human mast cell tryptase tetramer: a fascinating riddle solved by structure.	TPSAB1 TPSB2	1.01e-05	2	111	2	10708850
Pubmed	Neutral ceramidase deficiency protects against cisplatin-induced acute kidney injury.	ASAH2 ASAH2B	1.01e-05	2	111	2	35151662
Pubmed	Tryptase haplotype in mastocytosis: relationship to disease variant and diagnostic utility of total tryptase levels.	TPSAB1 TPSB2	1.01e-05	2	111	2	17449330
Pubmed	Expression and sequence analysis of the mouse adenine nucleotide translocase 1 and 2 genes.	SLC25A4 SLC25A5	1.01e-05	2	111	2	10974536
Pubmed	Impact of naturally forming human α/β-tryptase heterotetramers in the pathogenesis of hereditary α-tryptasemia.	TPSAB1 TPSB2	1.01e-05	2	111	2	31337736
Pubmed	Identification of genetic drivers of plasma lipoprotein size in the Diversity Outbred mouse population.	ASAH2 ASAH2B	1.01e-05	2	111	2	37944753
Pubmed	Human smooth muscle myosin heavy chain isoforms as molecular markers for vascular development and atherosclerosis.	MYH10 MYH11	1.01e-05	2	111	2	7916668
Pubmed	Role of neutral ceramidase in colon cancer.	ASAH2 ASAH2B	1.01e-05	2	111	2	27609772
Pubmed	Investigation of the association between ATP2B4 and ATP5B genes with colorectal cancer.	ATP2B4 ATP5F1B	1.01e-05	2	111	2	24583174
Pubmed	Maturation of postnatally generated olfactory bulb granule cells depends on functional γ-protocadherin expression.	PCDHGA9 PCDHGA6 PCDHGA12	1.40e-05	15	111	3	23515096
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	ITGA2 ZDHHC8 PROM1 PTPRM JAG1 ATP2B4 PLXNA1 VPS13B PLXNA2 TNS3	1.49e-05	569	111	10	30639242
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	RPL21 MYH10 HECW1 SLC25A5 STXBP5L ZNFX1 NT5DC3 LRP1B SACM1L SLC6A11 ARFGAP3 KCTD16 CSTB ATP5F1B	1.65e-05	1139	111	14	36417873
Pubmed	Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding.	SLC25A4 CTSC CHD8 PFKM ARFGAP3 CSTB HARS1 GMPPA TNS3	1.88e-05	464	111	9	32457219
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	USP36 TENT4B RTCB NT5E PIEZO1 PPP1R12B CHD8 MPRIP SLC30A7 RBM22 GTF2H4 UTP25 ARFGAP3 NMT1 VDAC2 ATP5F1B	2.21e-05	1497	111	16	31527615
Pubmed	Interactome analysis of AMP-activated protein kinase (AMPK)-α1 and -β1 in INS-1 pancreatic beta-cells by affinity purification-mass spectrometry.	RPL21 MYH10 SLC25A5 PRKAG1 ATP5F1B	2.27e-05	105	111	5	24625528
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	RPL21 AARS1 MYH10 SLC25A5 RTCB MPRIP SF3B3 PRKAG1 NMT1 ATP5F1B	2.38e-05	601	111	10	33658012
Pubmed	Repression of rRNA transcription by PARIS contributes to Parkinson's disease.	RPL21 MYH11 SLC25A4 SLC25A5 PFKM SF3B3 ATP5F1B	2.81e-05	272	111	7	25315684
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	PIGN FAT4 TM9SF4 CTSC PIEZO1 PGAP4 ITGA2 LRP1B SACM1L TPCN1 SLC30A7 CSTB PLXNA1 ATP5F1B	2.96e-05	1201	111	14	35696571
Pubmed	Structural Basis for Plexin Activation and Regulation.	PLXNA1 PLXNA2	3.02e-05	3	111	2	27397516
Pubmed	Common fragile sites (CFS) and extremely large CFS genes are targets for human papillomavirus integrations and chromosome rearrangements in oropharyngeal squamous cell carcinoma.	LRP1B CSMD1	3.02e-05	3	111	2	27636103
Pubmed	The molecular circuitry regulating the switch between iron deficiency and overload in mice.	ASAH2 ASAH2B	3.02e-05	3	111	2	16418170
Pubmed	Identification of plexin family molecules in mice.	PLXNA1 PLXNA2	3.02e-05	3	111	2	8806646
Pubmed	Neutral ceramidase regulates breast cancer progression by metabolic programming of TREM2-associated macrophages.	ASAH2 ASAH2B	3.02e-05	3	111	2	38302493
Pubmed	Fyn-dependent phosphorylation of PlexinA1 and PlexinA2 at conserved tyrosines is essential for zebrafish eye development.	PLXNA1 PLXNA2	3.02e-05	3	111	2	29091353
Pubmed	Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells.	PLXNA1 PLXNA2	3.02e-05	3	111	2	18625214
Pubmed	Expression of type VI, IX and XI collagen genes and alternative splicing of type II collagen transcripts in fracture callus tissue in mice.	COL6A2 COL11A1	3.02e-05	3	111	2	7750564
Pubmed	Plexins promote Hedgehog signaling through their cytoplasmic GAP activity.	PLXNA1 PLXNA2	3.02e-05	3	111	2	36169302
Pubmed	Differential expression of plexin-A subfamily members in the mouse nervous system.	PLXNA1 PLXNA2	3.02e-05	3	111	2	11241833
Pubmed	Jagged-1 Signaling in the Bone Marrow Microenvironment Promotes Endothelial Progenitor Cell Expansion and Commitment of CD133+ Human Cord Blood Cells for Postnatal Vasculogenesis.	PROM1 JAG1	3.02e-05	3	111	2	27846321
Pubmed	The human mitochondrial ADP/ATP carriers: kinetic properties and biogenesis of wild-type and mutant proteins in the yeast S. cerevisiae.	SLC25A4 SLC25A5	3.02e-05	3	111	2	12450408
Pubmed	Identification of a functional hepatocyte nuclear factor 4 binding site in the neutral ceramidase promoter.	ASAH2 ASAH2B	3.02e-05	3	111	2	20803549
Pubmed	Expression of intestinal and lung alkaline sphingomyelinase and neutral ceramidase in cystic fibrosis f508del transgenic mice.	ASAH2 ASAH2B	3.02e-05	3	111	2	18955860
Pubmed	Distinct phosphatases antagonize the p53 response in different phases of the cell cycle.	PPM1D PPP4C	3.02e-05	3	111	2	24711418
Pubmed	Neutral ceramidase secreted by endothelial cells is released in part associated with caveolin-1.	ASAH2 ASAH2B	3.02e-05	3	111	2	12921776
Pubmed	Effects of h1-calponin ablation on the contractile properties of bladder versus vascular smooth muscle in mice lacking SM-B myosin.	MYH10 MYH11	3.02e-05	3	111	2	16973711
Pubmed	DNA sequences of two expressed nuclear genes for human mitochondrial ADP/ATP translocase.	SLC25A4 SLC25A5	3.02e-05	3	111	2	2541251
Pubmed	Characterization of genes encoding known and novel human mast cell tryptases on chromosome 16p13.3.	TPSAB1 TPSB2	3.02e-05	3	111	2	9920877
Pubmed	Two distinct genes for ADP/ATP translocase are expressed at the mRNA level in adult human liver.	SLC25A4 SLC25A5	3.02e-05	3	111	2	2829183
Pubmed	Carboxyatractyloside effects on brown-fat mitochondria imply that the adenine nucleotide translocator isoforms ANT1 and ANT2 may be responsible for basal and fatty-acid-induced uncoupling respectively.	SLC25A4 SLC25A5	3.02e-05	3	111	2	16831128
Pubmed	Human subjects are protected from mast cell tryptase deficiency despite frequent inheritance of loss-of-function mutations.	TPSAB1 TPSB2	3.02e-05	3	111	2	19748655
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	USP36 MYH10 SLC25A5 PPM1D PPP1R12B CCDC61 PPP4C PPP6C PTPRM HARS1 ATP2B4 PRRC2B TNS3	3.11e-05	1049	111	13	27880917
Pubmed	Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.	AARS1 MYH10 SLC25A5 RTCB SF3B3 KLHL13 FBXO21 ATP5F1B KLHL26	3.12e-05	495	111	9	28581483
Pubmed	A Genome-Wide Knockout Screen in Human Macrophages Identified Host Factors Modulating Salmonella Infection.	IMPA2 CTSC CCDC61 SF3B3 KLHL13 HARS1	3.36e-05	189	111	6	31594818
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	IMPA2 RTCB TM9SF4 PPP1R12B CHD8 SLC46A1 KIAA0319 PTPRM C5 ATP2B4 PCDH9 PLXNA1 ATP5F1B	3.50e-05	1061	111	13	33845483
Pubmed	Identification of the Mitochondrial Heme Metabolism Complex.	SLC25A4 SLC25A5 VDAC2	4.04e-05	21	111	3	26287972
Pubmed	CCT3 acts upstream of YAP and TFCP2 as a potential target and tumour biomarker in liver cancer.	RPL21 MYH10 MYH11 SLC25A4 SLC25A5 MPRIP ATP5F1B	4.05e-05	288	111	7	31501420
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	RPL21 USP36 AARS1 MYH10 RTCB PFKM MPRIP CSTB NMT1 PRRC2B VDAC2 ATP5F1B	4.53e-05	934	111	12	33916271
Pubmed	VE-822 upregulates the deubiquitinase OTUD1 to stabilize FHL1 to inhibit the progression of lung adenocarcinoma.	RTCB PFKM PRRC2B VDAC2 ATP5F1B	4.66e-05	122	111	5	36929488
Pubmed	Elucidation of the 14-3-3ζ interactome reveals critical roles of RNA-splicing factors during adipogenesis.	MYH10 MYH11 SLC25A4 SLC25A5 ATP5F1B	4.66e-05	122	111	5	29530978
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	MYH10 MYH11 SLC25A5 TM9SF4 ZNFX1 MPRIP	4.86e-05	202	111	6	33005030
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	MYH10 SACM1L KIAA0319 KLHL13 ASB1 VPS13B PLXNA2 PRRC2B	5.08e-05	407	111	8	12693553
Pubmed	ABCE1 is a highly conserved RNA silencing suppressor.	RPL21 AARS1 SLC25A4 PPP6C CSTB VDAC2	5.14e-05	204	111	6	25659154
Cytoband	5q31	PCDHGA9 PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1 PCDHGA12	3.96e-07	115	111	6	5q31
Cytoband	Ensembl 112 genes in cytogenetic band chr5q31	PCDHGA9 PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1 PCDHGA12 KCTD16 HARS1	7.10e-07	298	111	8	chr5q31
Cytoband	18p11.2	IMPA2 PTPRM	2.06e-04	9	111	2	18p11.2
Cytoband	Ensembl 112 genes in cytogenetic band chrXq24	SLC25A5 DOCK11 KLHL13	1.02e-03	81	111	3	chrXq24
Cytoband	9q34.13	PLPP7 PRRC2B	1.18e-03	21	111	2	9q34.13
Cytoband	1q32.2	UTP25 PLXNA2	1.95e-03	27	111	2	1q32.2
GeneFamily	Clustered protocadherins	PCDHGA9 PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1 PCDHGA12	4.39e-07	64	82	6	20
GeneFamily	Plexins	PLXNA1 PLXNA2	7.17e-04	9	82	2	683
GeneFamily	UPF1 like RNA helicases	ZNFX1 MOV10L1	1.09e-03	11	82	2	1169
GeneFamily	Protein phosphatase catalytic subunits\|EF-hand domain containing	PPP4C PPP6C	1.53e-03	13	82	2	693
GeneFamily	Myosin heavy chains	MYH10 MYH11	2.05e-03	15	82	2	1098
GeneFamily	Aminoacyl tRNA synthetases, Class II	AARS1 HARS1	3.30e-03	19	82	2	132
Coexpression	GSE16450_CTRL_VS_IFNA_6H_STIM_MATURE_NEURON_CELL_LINE_UP	ADAMTS19 FAT4 NT5E NT5DC3 ZDHHC8 LRP1B TPCN1 KLHL26	2.03e-06	199	110	8	M7420
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 COL11A1 HECW1 STXBP5L LRP1B SORCS1 CSMD1 MYO15A	1.93e-08	184	110	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 COL11A1 HECW1 STXBP5L LRP1B SORCS1 CSMD1 MYO15A	1.93e-08	184	110	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 COL11A1 HECW1 STXBP5L LRP1B SORCS1 CSMD1 MYO15A	1.93e-08	184	110	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	COL6A2 FAT4 MYH10 MYH11 ABI3BP PPP1R12B SORCS1 PROM1	3.54e-08	199	110	8	38cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	COL6A2 FAT4 MYH10 MYH11 ABI3BP PPP1R12B SORCS1 PROM1	3.68e-08	200	110	8	a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	COL6A2 MYH10 MYH11 RAP1GAP ABI3BP PPP1R12B PROM1 KLHL13	3.68e-08	200	110	8	593bf6a7c557437db9a9249a5058a46014179ef6
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL11A1 HECW1 LRP1B SLC6A11 MOV10L1 MYO15A ADGRF1	7.53e-08	145	110	7	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic-basophil\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TPSAB1 PCDHGA2 PCDHGA1 PGAP4 PROM1 KLHL13 TPSB2	9.50e-08	150	110	7	408b7c2c3a42f5455c8c26a83d9e366a1c8d5ecc
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	GPR155 ADAMTS19 PGGHG APCDD1 CTSC PFKFB4 SORCS1	4.25e-07	187	110	7	7e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA2 LRP1B PROM1 ARFGAP3 KLHL13 KCTD16 PCDH9	4.73e-07	190	110	7	bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA2 LRP1B PROM1 ARFGAP3 KLHL13 KCTD16 PCDH9	4.73e-07	190	110	7	b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCell	facs-Lung-nan-3m-Mesenchymal-pulmonary_interstitial_fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A2 MYH11 APCDD1 SORCS1 LRIG1 KCTD16 CSMD1	4.73e-07	190	110	7	c7bd087f36321cec61b98657433b4d19d135791f
ToppCell	facs-Lung-nan-3m-Mesenchymal-Myofibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A2 MYH11 APCDD1 SORCS1 LRIG1 KCTD16 CSMD1	4.73e-07	190	110	7	834218fcc59df5e7e52de154272f3d55d81d0dac
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABI3BP PGGHG DOCK11 CTSC PROM1 JAG1 KCTD16	5.25e-07	193	110	7	ffa1932da2979d7b63dbac32eb5788346a3f5b2a
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A2 MYH11 APCDD1 SORCS1 LRIG1 KCTD16 CSMD1	5.63e-07	195	110	7	c6bb16c0076639c6ddef1a15d8cba44bc29c077d
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A2 MYH11 APCDD1 SORCS1 LRIG1 KCTD16 CSMD1	5.63e-07	195	110	7	ea89f80d3d7e9f737442f7c1aa1791d277ffc90c
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS19 FAT4 MYH10 HECW1 ABI3BP GTF2H4 MOV10L1	6.03e-07	197	110	7	0dd71e399f253787fa546a7e90c5373180b89ffd
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	COL6A2 MYH10 MYH11 ABI3BP PPP1R12B PROM1 KLHL13	6.45e-07	199	110	7	e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	COL6A2 MYH10 MYH11 ABI3BP PPP1R12B PROM1 KLHL13	6.45e-07	199	110	7	6b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	COL6A2 MYH10 MYH11 ABI3BP PPP1R12B PROM1 KLHL13	6.67e-07	200	110	7	9d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	COL6A2 MYH10 MYH11 ABI3BP PPP1R12B PROM1 KLHL13	6.67e-07	200	110	7	87827041663013f5e7273168dc8709d69840e7ce
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	COL6A2 MYH10 MYH11 ABI3BP PPP1R12B SORCS1 PROM1	6.67e-07	200	110	7	09537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	COL6A2 MYH10 MYH11 ABI3BP PPP1R12B PROM1 KLHL13	6.67e-07	200	110	7	c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	COL6A2 MYH10 MYH11 ABI3BP PPP1R12B PROM1 KLHL13	6.67e-07	200	110	7	08bf8c00eee6468215edb3611296bfc8784c4d56
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic\|LPS_only / Treatment groups by lineage, cell group, cell type	COL6A2 MYH10 MYH11 ABI3BP PPP1R12B PROM1 KLHL13	6.67e-07	200	110	7	02cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS19 MYH11 COL11A1 LRP1B SORCS1 MOV10L1	2.91e-06	160	110	6	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS19 MYH11 COL11A1 LRP1B SORCS1 MOV10L1	2.91e-06	160	110	6	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-like-AT2_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GPR155 FBXL13 PGGHG EML5 LRIG1 ADSS1	3.85e-06	168	110	6	9e7b4b9b977e90e083f5164013e79df8bc2d492e
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MYH11 PPP1R12B MPRIP KLHL13 JAG1 CSMD1	4.71e-06	174	110	6	015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYH11 RAP1GAP STXBP5L SLC46A1 EML5 KLHL26	5.20e-06	177	110	6	8abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCell	control-Others-CD34+_GATA2+_cells\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	TPSAB1 MYH10 PGAP4 PROM1 KLHL13 TPSB2	5.37e-06	178	110	6	2120bd3e099b0b271bf079db9827a2f3eee2f909
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 EML6 PROM1 JAG1 KCTD16 ADGRF1	5.37e-06	178	110	6	c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCell	Control-Hematopoietic_SC-HSPC\|Control / Disease group, lineage and cell class	TPSAB1 MYH10 PGAP4 PROM1 PCDH9 TPSB2	6.10e-06	182	110	6	14e347c0e6444410f1948851407bb18c706569f4
ToppCell	Control-Hematopoietic_SC\|Control / Disease group, lineage and cell class	TPSAB1 MYH10 PGAP4 PROM1 PCDH9 TPSB2	6.10e-06	182	110	6	43243c6bae2ac7fa3fd1f193a17f61ee4d938ea9
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABI3BP PTPRM KLHL13 JAG1 ATP2B4 PLXNA2	6.49e-06	184	110	6	087666ba949b129c53d7ace40f9e543e3875a7de
ToppCell	COVID-19_Moderate-HSPC\|World / disease group, cell group and cell class	TPSAB1 MYH10 PGAP4 PROM1 PCDH9 TPSB2	6.49e-06	184	110	6	ccc93babe1fcdeb66b78e1d8414357877a7c45bd
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYH10 MYH11 ABI3BP SORCS1 PROM1 KLHL13	6.70e-06	185	110	6	6712512100ccef456d2e2bd201d0987986c92ac9
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYH10 MYH11 ABI3BP SORCS1 PROM1 KLHL13	6.70e-06	185	110	6	3b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	MYH11 COL11A1 NT5E LIX1L SORCS1 PLXNA2	6.90e-06	186	110	6	e044b3428b7eacfdc72d0f57cdabaa1de04c74cd
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	COL6A2 MYH10 MYH11 COL11A1 PPP1R12B JAG1	7.12e-06	187	110	6	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYH10 MYH11 ABI3BP PPP1R12B PROM1 KLHL13	7.34e-06	188	110	6	293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 EML6 PROM1 JAG1 KCTD16 TNS3	7.57e-06	189	110	6	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A2 MYH11 ABI3BP PPP1R12B PROM1 KLHL13	7.57e-06	189	110	6	7ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCell	E18.5-samps-Mesenchymal\|E18.5-samps / Age Group, Lineage, Cell class and subclass	COL6A2 MYH10 MYH11 ABI3BP ATP2B4 TNS3	7.57e-06	189	110	6	0c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCell	Healthy-HSPC\|Healthy / disease group, cell group and cell class	TPSAB1 MYH10 PGAP4 PROM1 PCDH9 TPSB2	7.57e-06	189	110	6	214b225effc40ca1b83dd8052f2a7b80b65d4938
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RAP1GAP SLC25A4 SLC25A5 UHMK1 ADGRF1 ATP5F1B	8.03e-06	191	110	6	8b34e06c398056e857a10c7653c70c0b1f181692
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1B PROM1 KLHL13 KCTD16 ADGRF1 PCDH9	8.03e-06	191	110	6	2fa1b9e76a0ed2d2f0de74349e266cf4a5f51aad
ToppCell	Mesenchymal-vascular_smooth_muscle_cell\|World / Lineage, Cell type, age group and donor	COL6A2 MYH10 MYH11 PPP1R12B JAG1 CSMD1	8.03e-06	191	110	6	fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A2 MYH11 ABI3BP PPP1R12B PROM1 KLHL13	8.28e-06	192	110	6	992d08092edbc68c47b945deb8708379738c239a
ToppCell	COPD-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	MYH10 ITGA2 PTPRM KCTD16 PLXNA2 TNS3	8.28e-06	192	110	6	62904f94dfce430456f05066522cbf9bd29f4d7e
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYH11 ABI3BP SLC25A4 PPP1R12B PROM1 ATP2B4	8.53e-06	193	110	6	a402e736440684ebe123673b6b0c6fcd8fa057b2
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A2 MYH10 ABI3BP PCDHGA9 PROM1 TNS3	8.53e-06	193	110	6	1b2cc627b2aa002b442358bd1188d470e67ce7d9
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-Z\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TPSAB1 COL6A2 SLC25A5 CSTB TPSB2 VDAC2	9.04e-06	195	110	6	1f07502597e9476345b07f9f25aeeb6c1de13013
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYH10 HECW1 STXBP5L EML6 KCTD16 CSMD1	9.31e-06	196	110	6	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A2 FAT4 MYH10 HECW1 ABI3BP APCDD1	9.31e-06	196	110	6	e7bfd4fb400ae0c473131d0fa306c26be08a6d03
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A2 FAT4 MYH10 HECW1 ABI3BP APCDD1	9.31e-06	196	110	6	82fad623212d986a7fca3496faf3f8c8f5b83a11
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A2 FAT4 MYH10 HECW1 ABI3BP APCDD1	9.31e-06	196	110	6	85e5046f774537684e1443c0fc147d562b7068d0
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYH10 HECW1 STXBP5L EML6 KCTD16 CSMD1	9.86e-06	198	110	6	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	Parenchymal-10x3prime_v2-Stromal-Myofibroblastic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A2 MYH10 MYH11 PPP1R12B NT5DC3 JAG1	1.01e-05	199	110	6	9a08c25bb4851ad4ac9db8916422280f71378c2c
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL11A1 HECW1 APCDD1 STXBP5L LRP1B CSMD1	1.01e-05	199	110	6	333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCell	Sepsis-ICU-SEP-Lymphocyte-T/NK-CD8+_Tcm\|ICU-SEP / Disease, condition lineage and cell class	RPL21 MYH11 FBXL13 NT5E ITGA2 CD3G	1.01e-05	199	110	6	d0b45c8f914b719f79a2b80b0c0dfb5caf2a3a38
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL11A1 HECW1 APCDD1 STXBP5L LRP1B CSMD1	1.01e-05	199	110	6	e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCell	Parenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A2 MYH10 MYH11 PPP1R12B NT5DC3 JAG1	1.01e-05	199	110	6	2ed10c5e15c9d5ed0a8bea580842348d5698a07b
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	COL6A2 MYH11 PPP1R12B MPRIP JAG1 CSMD1	1.04e-05	200	110	6	9169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCell	Macroglial-Polydendrocytes-PDGFRA-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	COL11A1 HECW1 STXBP5L SORCS1 KCTD16 CSMD1	1.04e-05	200	110	6	f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCell	Macroglial-Polydendrocytes-PDGFRA--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	COL11A1 HECW1 STXBP5L SORCS1 KCTD16 CSMD1	1.04e-05	200	110	6	cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	COL6A2 MYH11 ABI3BP PPP1R12B PROM1 KLHL13	1.04e-05	200	110	6	f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial-Astrocyte\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	COL11A1 FBXL13 ITGA2 TPCN1 PROM1 UTP25	1.04e-05	200	110	6	98a994692440cb4f505b050276f0c8022c814a21
ToppCell	Macroglial-Polydendrocytes-PDGFRA\|Macroglial / cells hierarchy compared to all cells using T-Statistic	COL11A1 HECW1 STXBP5L SORCS1 KCTD16 CSMD1	1.04e-05	200	110	6	c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MYH10 MYH11 ABI3BP PPP1R12B PROM1 KLHL13	1.04e-05	200	110	6	8988f113708eef7d9d2a6a6c1bcfd7c8f9804d3e
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	COL6A2 MYH10 MYH11 ABI3BP PPP1R12B PROM1	1.04e-05	200	110	6	67dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte\|LPS_only / Treatment groups by lineage, cell group, cell type	COL6A2 MYH11 PPP1R12B MPRIP JAG1 CSMD1	1.04e-05	200	110	6	8c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	COL6A2 MYH10 MYH11 ABI3BP PPP1R12B PROM1	1.04e-05	200	110	6	a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCell	Macroglial-Polydendrocytes-PDGFRA---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	COL11A1 HECW1 STXBP5L SORCS1 KCTD16 CSMD1	1.04e-05	200	110	6	4fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	COL11A1 FBXL13 ITGA2 TPCN1 PROM1 UTP25	1.04e-05	200	110	6	ef222dc4a205d670172dae74990bdb952ac92e5b
ToppCell	Macroglial-Polydendrocytes-PDGFRA----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	COL11A1 HECW1 STXBP5L SORCS1 KCTD16 CSMD1	1.04e-05	200	110	6	310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCell	LPS_only-Mesenchymal_myocytic\|LPS_only / Treatment groups by lineage, cell group, cell type	COL6A2 MYH10 MYH11 ABI3BP PPP1R12B PROM1	1.04e-05	200	110	6	8bc9923f82bfb836e2f524204c92050edeae8ca5
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A2 FAT4 HECW1 ABI3BP APCDD1 KLHL13	1.04e-05	200	110	6	fb53be20392a8309a7393774c774a1b1aec6e676
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_only / Treatment groups by lineage, cell group, cell type	MYH11 PPP1R12B MPRIP JAG1 CSMD1 PCDH9	1.04e-05	200	110	6	7c62678cf408aaaf98d6df0fb27814d2007c4521
ToppCell	Macroglial-Polydendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	COL11A1 HECW1 STXBP5L SORCS1 KCTD16 CSMD1	1.04e-05	200	110	6	961858738ce35db8760c8c2e136f8369bc444ccf
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A2 FAT4 HECW1 ABI3BP APCDD1 KLHL13	1.04e-05	200	110	6	58b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCell	ICU-SEP-Lymphocyte-T_NK-CD8_TCM\|ICU-SEP / Disease, Lineage and Cell Type	RPL21 FBXL13 NT5E ITGA2 CD3G	4.42e-05	157	110	5	8ff52e532b149887c18f76b151325281821692b5
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL11A1 PCDHGA5 CSMD1 ADGRF1 PCDH9	4.42e-05	157	110	5	1f21d78a467fe22c5ab75d0917b840c1ac93f32c
ToppCell	COVID_non-vent-Myeloid-Monocytic-SC_&_Eosinophil\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	TPSAB1 PCDHGA5 PGAP4 PROM1 KLHL13	4.56e-05	158	110	5	0d4fe87fc7901dd5f9c004e91708a03cafdb4ad9
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	COL6A2 CCDC61 CD3G UHMK1 ATP2B4	4.84e-05	160	110	5	79e833c904c762434993b5ec9d5e3540e695fad3
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	MYH11 ABI3BP PPP1R12B LRP1B LRIG1	5.29e-05	163	110	5	1e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCell	Multiple_Sclerosis-Other-HSPC\|Multiple_Sclerosis / Disease, Lineage and Cell Type	TPSAB1 PGAP4 PROM1 KLHL13 TPSB2	5.44e-05	164	110	5	6af5529507d695b347adee4be5ead70f56c9cf55
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL6A2 MYH10 MYH11 PCDHGA1 JAG1	5.60e-05	165	110	5	8a82e20c9b1156bb4bbc16f7785abb04458d671b
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A2 COL11A1 SLC25A5 PFKM GTF2H4	5.76e-05	166	110	5	37794a84601a2a949d579663d4a4bb8bc8fb5923
ToppCell	droplet-Limb_Muscle-nan-3m-Myeloid-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPSAB1 PCDHGA1 EML6 ITGA2 TPSB2	5.76e-05	166	110	5	0a7992bc673fca546636563ec3fc17a4298ab6b1
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PGGHG NT5E CCDC61 KIAA0319 C5	5.76e-05	166	110	5	43f84d3cd58e93ce00c241656c4cba27604b4932
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A2 COL11A1 SLC25A5 PFKM GTF2H4	5.76e-05	166	110	5	81c546c6d847e49e662b81e71992ca0f7a99e890
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RPL21 SLC25A4 SLC25A5 PCDH9 ATP5F1B	6.27e-05	169	110	5	42c31fe94e34f54dbbb5d8b33cedb55badd6232c
ToppCell	droplet-Liver-LIVER-NPC-1m-Lymphocytic-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK11 PPP1R12B TPCN1 CD3G KLHL26	6.45e-05	170	110	5	3ad9f950b87ee98f025ab9b4a8ed551e6a9b4764
ToppCell	mild-Others-CD34+_GATA2+_cells\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	TPSAB1 PGAP4 PROM1 KLHL13 TPSB2	6.82e-05	172	110	5	379f6f271e653d5e404851e51a189bd582bb0f43
ToppCell	severe_COVID-19-HSPC\|severe_COVID-19 / disease group, cell group and cell class (v2)	ABI3BP PGAP4 PROM1 KLHL13 TPSB2	7.20e-05	174	110	5	6d35bacf073537b272ff821e604c899fb9ce6a7c
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAT4 MYH10 MYH11 ABI3BP PPP1R12B	7.40e-05	175	110	5	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	Control-Lymphocyte-T_NK-CD8_TCM\|Control / Disease, Lineage and Cell Type	RPL21 GPR155 NT5E CD3G EML5	7.60e-05	176	110	5	1a7948eb86ee1da607db4d0576312b2859d94523
ToppCell	(00)_Basal-(2)_48hpi\|(00)_Basal / shred by cell type and Timepoint	SLC25A4 SLC25A5 PROM1 ARFGAP3 VDAC2	7.60e-05	176	110	5	0f6770296d7fa453ffbf6ca6d5fdebc888f6eb60
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 EML6 PROM1 JAG1 TNS3	7.60e-05	176	110	5	327a3e81b724252e36d786de92a3ffd721ea6d7b
Drug	Phe-pro-arg	TPSAB1 CTSC UHMK1 CSTB TPSB2	1.57e-06	41	110	5	CID000133189
Drug	creatine	MYH10 MYH11 HECW1 SLC25A4 SLC25A5 PFKM SLC6A11 VDAC2	4.52e-06	193	110	8	CID000000586
Drug	Dicyclomine hydrochloride [67-92-5]; Down 200; 11.6uM; PC3; HG-U133A	RAP1GAP TM9SF4 SF3B3 PPP4C PLXNA1 PLXNA2 PRRC2B KLHL26	5.45e-06	198	110	8	1902_DN
Drug	butter yellow	TPSAB1 CTSC ASB1 TPSB2	1.28e-05	30	110	4	CID000007340
Drug	pimaradiene	TPSAB1 NT5E TPSB2	1.76e-05	11	110	3	CID000440909
Drug	methoxytrimethylsilane	ITGA2 CSTB	2.31e-05	2	110	2	CID000015771
Drug	N,N'-diphenylbenzamidine	ITGA2 PPP4C	2.31e-05	2	110	2	CID000075709
Drug	methylphosphine	ITGA2 PPP4C	2.31e-05	2	110	2	CID000068973
Drug	dimethylzinc	NT5E PPP4C	2.31e-05	2	110	2	CID000011010
Disease	mental development measurement	PCDHGA9 PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1	3.14e-08	25	109	5	EFO_0008230
Disease	childhood trauma measurement, alcohol consumption measurement	PCDHGA9 PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1 PCDHGA12	2.61e-07	71	109	6	EFO_0007878, EFO_0007979
Disease	Sarcosine measurement	PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1	1.48e-06	23	109	4	EFO_0021668
Disease	mean platelet volume	MYH11 AOC1 DOCK11 PCDHGA9 PCDHGA6 PCDHGA5 PCDHGA2 PCDHGA1 EML6 ITGA2 PFKFB4 MPRIP PCDHGA12 ATP5F1B	2.41e-05	1020	109	14	EFO_0004584
Disease	autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2 (implicated_via_orthology)	SLC25A4 SLC25A5	8.07e-05	4	109	2	DOID:0111517 (implicated_via_orthology)
Disease	Hypotrichosis simplex	RPL21 APCDD1	2.81e-04	7	109	2	C1854310
Disease	cerebellar ataxia (implicated_via_orthology)	AARS1 PNPLA7	3.73e-04	8	109	2	DOID:0050753 (implicated_via_orthology)
Disease	blindness (implicated_via_orthology)	PNPLA7 MYO15A	3.73e-04	8	109	2	DOID:1432 (implicated_via_orthology)
Disease	overall survival	CTSC PCDH9	4.79e-04	9	109	2	EFO_0000638
Disease	tryptase beta-2 measurement	TPSAB1 TPSB2	4.79e-04	9	109	2	EFO_0008306
Disease	Facies	CHD8 JAG1	5.97e-04	10	109	2	C0282631
Disease	hydroxyproline measurement	SORCS1 CSMD1	5.97e-04	10	109	2	EFO_0010498
Disease	response to carboplatin, response to antineoplastic agent	LRIG1 CSMD1	5.97e-04	10	109	2	GO_0097327, GO_0097328
Disease	pneumonia, COVID-19	LRP1B SACM1L CSMD1 VPS13B	8.33e-04	113	109	4	EFO_0003106, MONDO_0100096
Disease	amino acid measurement	PIGN ADAMTS19 FAT4 MYH10 ITGA2 LRIG1 C5 CSMD1 PLXNA2	9.38e-04	678	109	9	EFO_0005134
Disease	Familial thoracic aortic aneurysm and aortic dissection	MYH11 COL11A1 JAG1	1.00e-03	53	109	3	C4707243
Disease	sugar consumption measurement	SORCS1 CSMD1 VPS13B PLXNA2	1.04e-03	120	109	4	EFO_0010158
Disease	beta-amyloid 1-42 measurement, cerebrospinal fluid biomarker measurement	FAT4 HECW1	1.20e-03	14	109	2	EFO_0004670, EFO_0006794
Disease	susceptibility to hepatitis B infection measurement	HLA-DRB3 EML6 CSMD1	1.73e-03	64	109	3	EFO_0008405
Disease	uric acid measurement	PIGN FAT4 PLPP7 KIAA0319 LRIG1 JAG1 CSTB PRRC2B	1.95e-03	610	109	8	EFO_0004761
Disease	Malignant neoplasm of breast	ADAMTS19 COL11A1 RAP1GAP PPM1D PPP1R12B PFKFB4 SORCS1 ARFGAP3 JAG1 MAGEC2 VPS13B	2.10e-03	1074	109	11	C0006142
Disease	bipolar disorder (is_marker_for)	RAP1GAP IMPA2	2.22e-03	19	109	2	DOID:3312 (is_marker_for)
Disease	melanoma	FAT4 RAP1GAP LRP1B SLC6A11 PPP6C	2.31e-03	248	109	5	C0025202
Disease	temporal horn of lateral ventricle volume measurement	COL11A1 PTPRM CSMD1	2.43e-03	72	109	3	EFO_0010333
Disease	urticaria	TPSAB1 TPSB2	2.46e-03	20	109	2	EFO_0005531
Disease	nucleotide measurement	AOC1 ITGA2 PLXNA2	2.53e-03	73	109	3	EFO_0010513
Disease	DNA methylation	FAT4 SPAM1 LRP1B PTPRM CSMD1 NMT1 ATP2B4 TNS3	3.04e-03	656	109	8	GO_0006306
Disease	Glioblastoma	PROM1 JAG1 CSTB	3.16e-03	79	109	3	C0017636
Disease	HbA1c measurement	USP36 GPR155 PIEZO1 PFKM LRIG1 PRKAG1 MYO15A ATP2B4	3.61e-03	675	109	8	EFO_0004541

Protein segments in the cluster

Peptide	Gene	Start	Entry
TPVYVALGIFVQHRV	PRKAG1	211	P54619
GLQVDYVFRGVEHAV	CCDC61	6	Q9Y6R9
SIAFLQEVYNVGIHG	CHD8	846	Q9HCK8
VGVYFIAGQDGVRQS	CD3G	131	P09693
VFANGVVTSIQDRYG	ARFGAP3	501	Q9NP61
GHGVYINFTLLQTEA	CSMD1	2181	Q96PZ7
TQFRNGSIVAGYEVV	ADGRF1	201	Q5T601
YRVGEVAEVIFVGAN	ASAH2B	51	P0C7U1
FNRQLQTEVGYGHVQ	CEACAM16	111	Q2WEN9
GQTALYVAVVNGHLE	ASB1	111	Q9Y576
VVFENVALGYHVGSV	FAT4	801	Q6V0I7
GFNVSVQGIIIYRAA	SLC25A5	176	P05141
QVVAGTNYFIKVHVG	CSTB	46	P04080
VLNVHFGGERIAYEV	AOC1	336	P19801
GYVVGQALQLHADVE	ARRDC1	176	Q8N5I2
TVVQAYIGGIHYRQI	ATP2B4	476	P23634
NIVGSEHYDVARGVQ	ATP5F1B	411	P06576
HFYQFGEIRTITVVQ	RBM22	251	Q9NW64
VGVDGVRAFLQTYSH	PCDHGA2	741	Q9Y5H1
FNHTRGAGYVEVLVI	ADAMTS19	796	Q8TE59
VGVDGVRAFLQTYSH	PCDHGA5	741	Q9Y5G8
VGVDGVQAFLQTYSH	PCDHGA12	741	O60330
RNYNQGVVGLHEEIS	TENT4B	111	Q8NDF8
LIGQHVTAALYGVVN	FBXO21	366	O94952
VGVEGVRAFLQTYSH	PCDHGA6	741	Q9Y5G7
SVFVVQLQLHVGYFV	SLC46A1	131	Q96NT5
VVVEHGTYGNRQVLK	DTD2	141	Q96FN9
VQRNYGFQIHTKEGE	MPRIP	446	Q6WCQ1
VVDYQGKNRHTVIQG	LRP1B	396	Q9NZR2
YQIGVRVGHFTHVFV	MOV10L1	871	Q9BXT6
EVLNAVGVYAGREHF	MAGEC2	251	Q9UBF1
QVTFGHEGRYQCVIT	LRIG1	566	Q96JA1
VHLEGIFQAVYTAGV	NMT1	271	P30419
VVELNVGGQVYFTRH	KCTD16	26	Q68DU8
FNEYVIFVVTNRGQH	MYO15A	3251	Q9UKN7
QGGVIQHITNEYEFR	GPR155	811	Q7Z3F1
GVVQQTEALVRGFYE	HECW1	1451	Q76N89
YRVGEVAEVIFVGAN	ASAH2	666	Q9NR71
NAVHVNVGAGSYLEI	KIAA1109	406	Q2LD37
LSIYNEHGIQQIGVE	COL11A1	116	P12107
VHEQTGEVYVGAVNR	PLXNA1	56	Q9UIW2
HQGTGAVYVGAINRV	PLXNA2	56	O75051
VGVDGVRAFLQTYSQ	PCDHGA9	741	Q9Y5G4
IGSNAEIRYIFGAQV	PCDH9	281	Q9HC56
ARVFFVHEGYQGLVD	PFKM	46	P08237
VGQSYVVNRVADHIQ	PFKFB4	221	Q16877
HTQGYGRVNVVEALQ	LIX1L	91	Q8IVB5
IITVDRQPGFHYVLQ	PGAP4	106	Q9BRR3
DIYGVQEVHVNGAVV	PGGHG	361	Q32M88
YVAHVGDSGVVLGIQ	PPM1D	186	O15297
GFAVRQELEFGVIYH	IMPA2	121	O14732
ITVIQAHRGDQIGSY	ITGA2	476	P17301
FNEICEVGYQHGRTV	PNPLA7	1186	Q6ZV29
NYGVGESFTVQRRVH	HLA-DRB3	111	P79483
VFSALAGQGQIYVHL	GMPPA	226	Q96IJ6
LTIFGIQSHGYEVFN	GKN2	11	Q86XP6
QHGIAVIGNFLYVVG	KLHL13	381	Q9P2N7
VAVLDNFVYVAGGQH	KLHL26	356	Q53HC5
HGIAESQLRYIQQGI	DOCK11	451	Q5JSL3
FRVGASENIVIQVYG	C5	31	P01031
GVVQYSHEGTFEAIQ	COL6A2	661	P12110
SGHFTIIYNQGFEIV	CTSC	81	P53634
IIRGGTEADYQLHNV	APCDD1	136	Q8J025
EHLTAQGIGYIVNIF	FBXL13	516	Q8NEE6
NIYQFAVGGHDQFVR	DCAF8L1	346	A6NGE4
INATGQGVTIFYVDR	SPAM1	81	P38567
YTQIGEIVYHVAAVG	EML5	696	Q05BV3
YVATGQVGRDAAIHV	EML6	741	Q6ZMW3
DGFQRHFDSQVIIYG	SACM1L	286	Q9NTJ5
RIGDYVQQHGGVSLV	HARS1	266	P12081
IRINFDVTGYIVGAN	MYH10	246	P35580
QVIFEVITSGHQGYL	PTPRM	156	P28827
KQNTGVAHFEYQIRV	JAG1	171	P78504
VGVDGVRAFLQTYSH	PCDHGA1	741	Q9Y5H4
TLGAGNHYAEIQVVD	RTCB	221	Q9Y3I0
VFVGNIDDHFRIGVA	UTP25	416	Q68CQ4
RIIVHPQFYTAQIGA	TPSAB1	106	Q15661
RIIVHPQFYTAQIGA	TPSB2	106	P20231
AQNYIRFVENHVGVA	ADSS1	426	Q8N142
HYIQLGTVYRGLSVV	NT5DC3	166	Q86UY8
SFHVVIGSQAEEGQY	GPR108	206	Q9NPR9
IGIFYGFVANHQVRT	PROM1	171	O43490
SNFLHAYVVVQAEGG	RAP1GAP	311	P47736
VIFRLQFHTGAVQGY	TNS3	256	Q68CZ2
YVGTERGNTHIVNIE	STXBP5L	171	Q9Y2K9
TGEFLQVGGIHVVYD	NT5E	446	P21589
GFNVSVQGIIIYRAA	SLC25A4	176	P12235
IRINFDVTGYIVGAN	MYH11	246	P35749
VHQPGFIVVETNYRL	GTF2H4	301	Q92759
VQFEHGYRLGFTDVN	TM9SF4	161	Q92544
FTVKNAQVRGGYVLH	AARS1	561	P49588
RGNHESRQITQVYGF	PPP6C	111	O00743
AVGYRTGDFQLHTNV	VDAC2	181	P45880
GSVQGHYVQQAKQRV	PRRC2B	2176	Q5JSZ5
TGRVYNVTQHAVGIV	RPL21	61	P46778
GIGYATQVIEAHLNV	SLC6A11	131	P48066
HTYDRFFLGVNVVIG	PIGN	436	O95427
IANYISGIQTIGHRV	SF3B3	986	Q15393
FAGVRVHVVDKYQGE	ZNFX1	1176	Q9P2E3
HNIFTQAGVRQLYVQ	SLC30A7	356	Q8NEW0
NHTVGNRTVVEEGYY	TPCN1	611	Q9ULQ1
VQHYIGQDGQAVVRE	VPS13B	2746	Q7Z7G8
VGVVAFGLVYVLNHA	ZDHHC8	161	Q9ULC8
QGGEVHRGVLDQLYT	PIEZO1	1556	Q92508
VQFGEIGGHTQINYV	ABI3BP	1041	Q7Z7G0
KHVYQNVGIFRVTVQ	SORCS1	856	Q8WY21
IRGNHESRQITQVYG	PPP4C	111	P60510
EQLQGHRNIVTLYGV	UHMK1	81	Q8TAS1
QATTLVHQIFGGYLR	USP36	236	Q9P275
HVTDVLSGFVIGYLQ	PLPP7	236	Q8NBV4
VTGLQVGTYHFRLTV	KIAA0319	681	Q5VV43
EYFINHGASVGIVNS	PPP1R12B	141	O60237