Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhigh-affinity L-glutamate transmembrane transporter activity

SLC1A3 SLC1A6

2.64e-055332GO:0005314
GeneOntologyMolecularFunctionglutamate:sodium symporter activity

SLC1A3 SLC1A6

2.64e-055332GO:0015501
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC24A5 SLC26A9 SLC1A3 SLC4A3 SLC1A6

1.17e-04296335GO:0015291
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC24A5 SLC26A9 SLC1A3 SLC4A3 SLC1A6

1.26e-04301335GO:0022853
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC24A5 CACNA1D SLC26A9 CATSPER2 SLC1A3 SLC4A3 SLC1A6

1.99e-04758337GO:0015318
GeneOntologyMolecularFunctionchloride:bicarbonate antiporter activity

SLC26A9 SLC4A3

2.04e-0413332GO:0140900
GeneOntologyMolecularFunctionbicarbonate:monoatomic anion antiporter activity

SLC26A9 SLC4A3

2.04e-0413332GO:0140829
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC24A5 CACNA1D SLC26A9 CATSPER2 SLC1A3 SLC4A3 SLC1A6

2.62e-04793337GO:0015075
GeneOntologyMolecularFunctionL-glutamate transmembrane transporter activity

SLC1A3 SLC1A6

2.74e-0415332GO:0005313
GeneOntologyMolecularFunctionacidic amino acid transmembrane transporter activity

SLC1A3 SLC1A6

4.94e-0420332GO:0015172
GeneOntologyMolecularFunctionamino acid:sodium symporter activity

SLC1A3 SLC1A6

6.56e-0423332GO:0005283
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC24A5 CACNA1D CATSPER2 SLC1A3 SLC1A6

9.28e-04465335GO:0046873
GeneOntologyMolecularFunctiontransporter activity

SLC24A5 CACNA1D SLC26A9 CATSPER2 SLC1A3 SLC4A3 SLC1A6 CETP

9.58e-041289338GO:0005215
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH2 RAB11FIP3

9.75e-0428332GO:0051959
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC24A5 SLC26A9 SLC1A3 SLC4A3 SLC1A6

1.04e-03477335GO:0022804
GeneOntologyMolecularFunctionamino acid:monoatomic cation symporter activity

SLC1A3 SLC1A6

1.05e-0329332GO:0005416
GeneOntologyMolecularFunctiondicarboxylic acid transmembrane transporter activity

SLC26A9 SLC1A6

1.20e-0331332GO:0005310
GeneOntologyMolecularFunctioncalcium channel activity

SLC24A5 CACNA1D CATSPER2

1.25e-03129333GO:0005262
GeneOntologyMolecularFunctionbicarbonate transmembrane transporter activity

SLC26A9 SLC4A3

1.27e-0332332GO:0015106
GeneOntologyMolecularFunctionsolute:inorganic anion antiporter activity

SLC26A9 SLC4A3

1.27e-0332332GO:0005452
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC26A9 SLC1A3 SLC4A3 SLC1A6

1.33e-03293334GO:0008514
GeneOntologyMolecularFunctionantiporter activity

SLC24A5 SLC26A9 SLC4A3

1.51e-03138333GO:0015297
GeneOntologyMolecularFunctionorganic acid:sodium symporter activity

SLC1A3 SLC1A6

1.52e-0335332GO:0005343
GeneOntologyMolecularFunctionsymporter activity

SLC24A5 SLC1A3 SLC1A6

1.92e-03150333GO:0015293
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC26A9 SLC4A3 SLC1A6

1.96e-03151333GO:0008509
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

SLC24A5 CACNA1D CATSPER2

1.96e-03151333GO:0015085
GeneOntologyMolecularFunctionneutral L-amino acid transmembrane transporter activity

SLC1A3 SLC1A6

2.09e-0341332GO:0015175
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

CACNA1D CATSPER2

2.62e-0346332GO:0005245
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC24A5 CACNA1D SLC26A9 CATSPER2 SLC1A3 SLC4A3 SLC1A6

2.72e-031180337GO:0022857
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC24A5 SLC1A3 SLC1A6

2.79e-03171333GO:0015081
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC24A5 CACNA1D CATSPER2 SLC1A3 SLC1A6

3.44e-03627335GO:0022890
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC24A5 CACNA1D CATSPER2 SLC1A3 SLC1A6

4.39e-03664335GO:0008324
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC26A9 SLC1A3 SLC1A6

4.76e-03207333GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC26A9 SLC1A3 SLC1A6

4.83e-03208333GO:0005342
GeneOntologyMolecularFunctionL-amino acid transmembrane transporter activity

SLC1A3 SLC1A6

6.13e-0371332GO:0015179
GeneOntologyMolecularFunctionmonoatomic ion channel activity

SLC24A5 CACNA1D SLC26A9 CATSPER2

6.65e-03459334GO:0005216
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC1A3 SLC1A6

7.91e-0381332GO:0015370
GeneOntologyMolecularFunctionchannel activity

SLC24A5 CACNA1D SLC26A9 CATSPER2

1.06e-02525334GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

SLC24A5 CACNA1D SLC26A9 CATSPER2

1.06e-02526334GO:0022803
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC1A3 SLC1A6

1.30e-02105332GO:0015171
GeneOntologyBiologicalProcessL-aspartate import across plasma membrane

SLC1A3 SLC1A6

3.48e-056322GO:0140009
DomainNa-dicarboxylate_symporter

SLC1A3 SLC1A6

5.94e-057322IPR001991
DomainSDF

SLC1A3 SLC1A6

5.94e-057322PF00375
Domain-

SLC1A3 SLC1A6

5.94e-0573221.10.3860.10
DomainNA_DICARBOXYL_SYMP_1

SLC1A3 SLC1A6

5.94e-057322PS00713
DomainNA_DICARBOXYL_SYMP_2

SLC1A3 SLC1A6

5.94e-057322PS00714
DomainNa-dicarboxylate_symporter_CS

SLC1A3 SLC1A6

5.94e-057322IPR018107
DomainChannel_four-helix_dom

CACNA1D CATSPER2

4.28e-0357322IPR027359
Domain-

CACNA1D CATSPER2

4.28e-03573221.20.120.350
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC24A5 SLC26A9 SLC1A3 SLC4A3 SLC1A6

1.70e-06108275M823
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC24A5 SLC26A9 SLC1A3 SLC4A3 SLC1A6

1.78e-06109275MM15074
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC24A5 SLC26A9 SLC1A3 SLC4A3 SLC1A6

7.84e-05238275MM15076
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC24A5 SLC26A9 SLC1A3 SLC4A3 SLC1A6

9.70e-05249275M5988
PathwayREACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE

SLC1A3 SLC1A6

9.50e-0424272MM14834
PathwayREACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE

SLC1A3 SLC1A6

9.50e-0424272M630
Pubmed

Loss of cerebellar glutamate transporters EAAT4 and GLAST differentially affects the spontaneous firing pattern and survival of Purkinje cells.

SLC1A3 SLC1A6

8.73e-07233229741614
Pubmed

Glutamate transporters GLAST and EAAT4 regulate postischemic Purkinje cell death: an in vivo study using a cardiac arrest model in mice lacking GLAST or EAAT4.

SLC1A3 SLC1A6

8.73e-07233216647773
Pubmed

Differential roles of glial and neuronal glutamate transporters in Purkinje cell synapses.

SLC1A3 SLC1A6

8.73e-07233216177048
Pubmed

Association study of polymorphisms in the glutamate transporter genes SLC1A1, SLC1A3, and SLC1A6 with schizophrenia.

SLC1A3 SLC1A6

2.62e-06333217221839
Pubmed

Inositol 1,4,5-trisphosphate signaling maintains the activity of glutamate uptake in Bergmann glia.

SLC1A3 SLC1A6

2.62e-06333220958799
Pubmed

Posterior cerebellar Purkinje cells in an SCA5/SPARCA1 mouse model are especially vulnerable to the synergistic effect of loss of β-III spectrin and GLAST.

SLC1A3 SLC1A6

2.62e-06333228173092
Pubmed

Facilitated activation of metabotropic glutamate receptors in cerebellar Purkinje cells in glutamate transporter EAAT4-deficient mice.

SLC1A3 SLC1A6

2.62e-06333217727989
Pubmed

Gene expression of glutamate transporters SLC1A1, SLC1A3 and SLC1A6 in the cerebellar subregions of elderly schizophrenia patients and effects of antipsychotic treatment.

SLC1A3 SLC1A6

5.23e-06433222424243
Pubmed

Structure and functional expression of the cloned mouse neuronal high-affinity glutamate transporter.

SLC1A3 SLC1A6

5.23e-0643329379843
Pubmed

Impact of Reduced Cerebellar EAAT Expression on Purkinje Cell Firing Pattern of NPC1-deficient Mice.

SLC1A3 SLC1A6

5.23e-06433229463856
Pubmed

Changes in expression and distribution of the glutamate transporter EAAT4 in developing mouse Purkinje cells.

SLC1A3 SLC1A6

8.72e-0653329129177
Pubmed

Down-Regulation of Inpp5e Associated With Abnormal Ciliogenesis During Embryonic Neurodevelopment Under Inositol Deficiency.

PKHD1 MKKS

1.83e-05733234093381
Pubmed

Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.

ZFR RPL3 HCFC1 FTSJ3

1.23e-0427133432433965
Pubmed

The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates.

OR1F1 OR1J2

2.18e-042333210706615
Pubmed

NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure.

SLC4A3 SLC1A6

3.02e-042733223359859
Pubmed

SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses.

ZFR RPL3 HCFC1

3.68e-0414733333080218
Pubmed

HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.

ZFR HCFC1 FTSJ3

3.75e-0414833332538781
Cytoband16p13.3

OR1F1 PGAP6 RAB11FIP3

7.19e-0424433316p13.3
CytobandEnsembl 112 genes in cytogenetic band chr3p21

CACNA1D TOPAZ1 CDHR4

1.51e-03316333chr3p21
Cytoband3p21.31

TOPAZ1 CDHR4

2.37e-031003323p21.31
CytobandEnsembl 112 genes in cytogenetic band chr16p13

OR1F1 PGAP6 RAB11FIP3

3.52e-03426333chr16p13
CytobandEnsembl 112 genes in cytogenetic band chr5p13

ZFR SLC1A3

4.52e-03139332chr5p13
GeneFamilySolute carriers

SLC24A5 SLC26A9 SLC1A3 SLC4A3 SLC1A6

9.40e-05395225752
GeneFamilyOlfactory receptors, family 1

OR1F1 OR1J2

1.07e-0340222147
ToppCellwk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PKHD1 SGMS2 HCFC1 VEGFB RAB11FIP3

2.41e-07185335636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 GPHN CACNA1D BICDL1 RAB11FIP3

2.97e-071933353866667dd221612589ae50f5c52f73a183a49ce6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 GPHN CACNA1D BICDL1 RAB11FIP3

2.97e-0719333582e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-AT1_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC24A5 RPL3 SLC1A6 MCHR2

2.18e-06125334b1a12400f7070bdf09e87974c548a8b82e92b65e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 PAPLN BICDL1 RAB11FIP3

1.05e-051863345784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 PAPLN BICDL1 RAB11FIP3

1.08e-051873349d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RPL3 SLC4A3 GYPC VEGFB

1.12e-051893340a490730cdc912d5233de59057550de0e4065747
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 PAPLN BICDL1 RAB11FIP3

1.17e-051913343c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 PAPLN BICDL1 RAB11FIP3

1.17e-051913341c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 GPHN BICDL1 RAB11FIP3

1.24e-051943347002937e8903e037332a215d00fbc7c7843b33f2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 CACNA1D BICDL1 RAB11FIP3

1.24e-051943345eaaa81f4b2535f983c424aaef00077089526a5c
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_Tem-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TPRG1 BICDL1 RPL3 GYPC

1.32e-05197334836fcb20d3a1f9cf14f6fd505fbb6bad4650fd28
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_Tem|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TPRG1 BICDL1 RPL3 GYPC

1.32e-05197334902e2ce011a938c1de39ff53ebbb2ec5557e48bc
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH2 PKHD1 CETP

7.35e-05110333c80d1c3df75648e2c8f6832279c2acca63d76681
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_dendritic-CD1c-positive_myeloid_dendritic_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SGMS2 SLC4A3 CETP

1.67e-04145333f6ba6cf0c8d0ee87a7904485b27eb9261fcb6edd
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CACNA1D TPRG1 TMEM98

1.81e-0414933368661c8facfb638560bb2e2c20d509941286dacb
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-Naive_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

TPRG1 RPL3 CDHR4

2.03e-041553331020da8a2c30384d962fa204a030299fdfcbbf98
ToppCellsevere-Myeloid-pDC|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

PAPLN TMEM98 VEGFB

2.27e-041613339e8e8ac11f7fb8c8697357c21034b613f191db2b
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TPRG1 SLC1A3 SLC4A3

2.27e-04161333da9eecf919866a9c579d7a707a996cf335213134
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TPRG1 SLC1A3 SLC4A3

2.27e-04161333d431625c32f59a6b552191f3adc5198bd16ad5cf
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNAH2 DCLRE1C PGAP6

2.31e-04162333ec29c6f1c31e41ddcb041a49c593910edaf0532c
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TPRG1 BICDL1 FTSJ3

2.31e-041623336ffcf369d954c20ce036aa1d072cee4e205f728e
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TPRG1 BICDL1 FTSJ3

2.31e-04162333bcbf7f80a2a1c80def795e345f16cf16e8b9d03b
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_dendritic|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TMEM98 SLC4A3 SLC1A6

2.31e-04162333233011408f022647932c81ebab78f9813e3c6833
ToppCellsevere-Myeloid-pDC|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

PAPLN TMEM98 VEGFB

2.48e-04166333ae38850fde549b8dd6fb12f0ef80b428ade50485
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

GPHN BICDL1 RAB11FIP3

2.48e-04166333f4698fd08965936d51695d571bd10fb77330d916
ToppCellmild_COVID-19-pDC|World / disease group, cell group and cell class (v2)

PAPLN SLC4A3 VEGFB

2.75e-04172333dab2f1a05c7df58d9387b13271b3f1f1583f9ac3
ToppCellmild-Myeloid-pDC|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

PAPLN SLC4A3 VEGFB

2.95e-0417633359a9c262c252b7d220a025837922d98e9d6b0a24
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

PKHD1 BICDL1 RAB11FIP3

2.95e-0417633336f77d878a53b30465b0dea8333a3865dba75613
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC26A9 PAPLN CETP

2.99e-0417733376f5df101c693e5fa61554244d877fc8169ee66f
ToppCell10x5'v1-week_17-19-Myeloid_macrophage-stroma-erythroid_macrophage|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TPRG1 CETP GYPC

2.99e-04177333b647667da62a91dbe3890820142626e26aa779d2
ToppCellCOVID-19-kidney-PCT-S1/S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

PKHD1 BICDL1 RAB11FIP3

3.04e-0417833323a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BICDL1 PGAP6 RAB11FIP3

3.09e-04179333d0fa700648db8ce76a8aa689879a25048299fa40
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BICDL1 PGAP6 RAB11FIP3

3.09e-041793332e49b215b71438400aebb483f2c2c08d5e956961
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC26A9 PAPLN CETP

3.09e-04179333dfd5b25f2a6a5a8bf4714f1516cb0997de72b06f
ToppCellmild-Myeloid-pDC|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

PAPLN SLC4A3 VEGFB

3.15e-0418033338614155fa537d0defda914c531c697be0ef06d8
ToppCellCOVID-19-kidney-tDL|COVID-19 / Disease (COVID-19 only), tissue and cell type

PKHD1 BICDL1 RAB11FIP3

3.15e-04180333864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

PKHD1 BICDL1 RAB11FIP3

3.15e-04180333358923e4228035a3e90e2957392089219e90dcd7
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

PKHD1 BICDL1 RAB11FIP3

3.20e-041813336980ea624151da32b7f537f263e40fcb87a02e81
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D BICDL1 PGAP6

3.25e-04182333041bc819e6cf2618bf86bce8dfe2df673f392ba3
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D BICDL1 PGAP6

3.30e-0418333331ab55d5f3639f5964541d5eae23044dbda3356e
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

PKHD1 BICDL1 RAB11FIP3

3.30e-041833336878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TPRG1 SGMS2 TMEM98

3.30e-0418333327a57cd8ea924420e182f3d72f5b29b00dea8fa0
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

PKHD1 BICDL1 RAB11FIP3

3.35e-0418433351ed1ebfdef45149541917c66cbacad87072e51f
ToppCellCOVID-19-kidney-Mito-rich_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

PKHD1 BICDL1 RAB11FIP3

3.41e-041853331bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D BICDL1 PGAP6

3.41e-04185333898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

PKHD1 CACNA1D RAB11FIP3

3.41e-041853331d874608aa2062024323512f68889219471b2f00
ToppCellcontrol-Myeloid-pDC|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

PAPLN SLC4A3 VEGFB

3.46e-04186333fe31e9cf4575ee40b50489593c51d8c36c3cc532
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 PAPLN RAB11FIP3

3.52e-04187333f1356273bd3587b6883295edf15cb9cdb706c057
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 BICDL1 RAB11FIP3

3.52e-041873333ae3b8de1a195d4d5057cf3c64fcdb5f48681ce5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 PAPLN RAB11FIP3

3.52e-04187333dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN TMEM98 SLC1A3

3.57e-04188333505b6b4277d7dea87aee27191d0acca67928b8e6
ToppCellsevere_COVID-19-CD4+_Tcm|World / disease group, cell group and cell class (v2)

BICDL1 RPL3 GYPC

3.63e-041893338037fd4d799d95d9ca633a3efaf698539f696893
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 PAPLN RAB11FIP3

3.63e-0418933328b502611829e4a24caff2562545c7db97686099
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 PAPLN BICDL1

3.63e-041893333b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN TMEM98 SLC1A3

3.63e-04189333784ace2be87f2ecb19490f4974f63a559516e0eb
ToppCellCOVID-19-kidney-PCT-S2|kidney / Disease (COVID-19 only), tissue and cell type

PKHD1 BICDL1 RAB11FIP3

3.63e-041893330be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN TMEM98 SLC1A3

3.63e-0418933337ecbd73408d462b47d7e5611f203143e08a2689
ToppCellCOPD-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

TPRG1 SGMS2 GYPC

3.68e-041903339fc763d65470ba8858b973689c4d4358faab7dd3
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 PAPLN RAB11FIP3

3.68e-04190333989d4eefd22d66ecb857836f8fdbcf41e3047f84
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1D PAPLN SLC1A3

3.68e-0419033345df8fee00f8949937863159d7aa042e72748d9b
ToppCellBAL-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DNAH2 TMEM98 CDHR4

3.74e-04191333df8a1a6e78aa0cb941b94cb676bd6891d79f3687
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DNAH2 TMEM98 CDHR4

3.74e-041913337b5da29109aa28768c67653a1bc0f385c2d2269b
ToppCellHealthy_Control-Epithelial-Epithelial|Healthy_Control / Condition, Lineage, Cell class and cell subclass

DNAH2 TMEM98 CDHR4

3.74e-0419133315b9386b26caaa7d15f704c4a18881e1ce918a21
ToppCellBAL-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DNAH2 TMEM98 CDHR4

3.74e-041913339f19098f260d5542aa8ba7eb6f91b44d0db6e0a4
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_T-CytoT_GZMK+-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TPRG1 BICDL1 GYPC

3.74e-04191333752e31a4b8aab9243b0451f4c40c2940ae9a5252
ToppCellsevere_COVID-19-CD4+_Tcm|severe_COVID-19 / disease group, cell group and cell class (v2)

BICDL1 RPL3 GYPC

3.74e-041913331ec86eaf90411ed200dbf51ae0cb5ed8060a7ec7
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH2 TMEM98 CDHR4

3.74e-04191333fa9f8b50bfc7911c858bc2f9dcd204873d97ac61
ToppCellControl-Epithelial|Control / Disease group,lineage and cell class （2021.01.30）

DNAH2 TMEM98 CDHR4

3.74e-04191333b78547dae8328244a47c83346447bdd787efbcae
ToppCellHealthy_Control-Epithelial-Epithelial-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

DNAH2 TMEM98 CDHR4

3.74e-0419133328caedb2e448e0c7f494100d714fa7cdcf150691
ToppCellControl-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

TPRG1 SGMS2 GYPC

3.74e-04191333a7bb8aba9c59c037d995a77928cc7b4d5cbb82b9
ToppCell(12)_SLC16A7+|World / shred by cell type by condition

DNAH2 MCHR2 CDHR4

3.74e-04191333e427eeddd2e87c14376a37db0b43f120c90436bc
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DNAH2 TMEM98 CDHR4

3.74e-04191333b4e335e798c9617356b8e24412f9270c42dce656
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH2 TMEM98 CDHR4

3.74e-04191333c4b223b33c020a064f576711a3d700eb60a2d737
ToppCellHealthy_Control-Epithelial|Healthy_Control / Condition, Lineage, Cell class and cell subclass

DNAH2 TMEM98 CDHR4

3.74e-04191333fdcdadbfc9ccae175abe4de8c7428ac4f6a67fde
ToppCellBAL-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH2 TMEM98 CDHR4

3.74e-04191333c50d6a1a6209ed4157f7c00fc24d4ecb43790f44
ToppCellBAL-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH2 TMEM98 CDHR4

3.74e-041913335129f778a9283bfac4ff322c21c5ca71da4b7174
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN TMEM98 SLC1A3

3.74e-04191333a90c8ab2077e52bbc998457c85a1b9867f9c8c93
ToppCellControl-Epithelial-Ciliated|Control / Disease group,lineage and cell class （2021.01.30）

DNAH2 TMEM98 CDHR4

3.74e-04191333cdc08e95a0c8f5c7a8d01b6bbaafdb54ef2f0d12
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_T-CytoT_GZMK+|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TPRG1 BICDL1 GYPC

3.80e-0419233371bc03b08cda0382ea45b503d5f4f135ed98cc11
ToppCellURO-Lymphocyte-T_NK-CD8_TEM|URO / Disease, Lineage and Cell Type

TPRG1 RPL3 GYPC

3.80e-0419233331b6d068f7adc6952c4cf625df851a10cb1b00c9
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 GPHN RAB11FIP3

3.80e-04192333e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GPHN SLC26A9 SGMS2

3.86e-04193333fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RPL3 SLC1A3 GYPC

3.86e-04193333f492ed02a46f3a45dc6005f9f18ab12a84bfa2a3
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GPHN SLC26A9 SGMS2

3.86e-04193333f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellCOVID-19_Severe-CD4+_Tcm|COVID-19_Severe / disease group, cell group and cell class

BICDL1 RPL3 GYPC

3.86e-0419333345fe14c10b71459047608c8931d83c9c533f97f9
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD4+_Th|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

BICDL1 RPL3 GYPC

3.86e-04193333ebb22400b683a7d135448822ad2a32cb1059e104
ToppCellICU-SEP-Lymphocyte-T_NK-CD8_TEM|ICU-SEP / Disease, Lineage and Cell Type

TPRG1 RPL3 GYPC

3.92e-041943335dbf0e3d8ccc389220f1fceaa2e99c85a1c4d818
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

GPHN SLC26A9 SGMS2

3.92e-0419433397534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCellInt-URO-Lymphocyte-T_NK-CD8_TEM|Int-URO / Disease, Lineage and Cell Type

TPRG1 RPL3 GYPC

3.92e-04194333e35bf4ef39e377bd0f56e5020a4c016ba66b8570
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 PAPLN TMEM98

3.92e-0419433370185c0b8e0f4e896645b17a243482ba3cdf4a5d
ToppCellHealthy-CD8+_Tem|World / disease group, cell group and cell class

TPRG1 RPL3 GYPC

3.97e-041953333d6f46b31c0254e9577a560364694b42964df198
ToppCellmild_COVID-19|World / disease group, cell group and cell class (v2)

BICDL1 RPL3 GYPC

3.97e-041953336dbe9db5f0e94f2e91b3d1282855d200051ab0ba
ToppCellHealthy_donor-CD8+_Tem|World / disease group, cell group and cell class (v2)

BICDL1 RPL3 GYPC

4.03e-04196333b04684d319d0c462862677d0f956a389bffef535
ToppCellPBMC-Control-Lymphocyte-T/NK-CD8+_T|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TPRG1 RPL3 GYPC

4.03e-04196333c06caba0c91b8ee66f42bc43ec75eb2475f07056
ToppCellPBMC-Control-Lymphocyte-T/NK-CD8+_T|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TPRG1 RPL3 GYPC

4.03e-04196333093fb240e72911dfd360aa6edf8ed2d611c78a1e
ToppCellHealthy/Control-CD8+_Tem|World / Disease group and Cell class

BICDL1 RPL3 GYPC

4.03e-04196333a6dc92476156a695e15373ea57dc04e30014ac55
ToppCellnormal-na-Hematopoietic|normal / PBMC cell types (v2) per disease, treatment status, and sex

TMEM98 SLC1A6 GYPC

4.03e-04196333c2c1c894706428bad5bfc81e9ae0f921ab1286d3
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RPL3 SLC1A6 GYPC

4.03e-04196333a9157809122e6fc5783a291522f103bef30943e4
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

BICDL1 RPL3 GYPC

4.09e-0419733333d841f4fcff8aeb0b988d5dd072166347bc6022
ComputationalGenes in the cancer module 186.

SLC1A3 SLC1A6

1.79e-0420112MODULE_186
Drugphenylgermanium

GPHN GYPC

2.04e-062332CID006396940
Diseaseepisodic ataxia type 6 (implicated_via_orthology)

SLC1A3 SLC1A6

1.81e-056332DOID:0050994 (implicated_via_orthology)
Diseasehair colour measurement

SLC24A5 PKHD1 TPRG1 RPL3 SLC1A3

5.67e-04615335EFO_0007822
DiseaseBipolar Disorder

CACNA1D SLC1A3 SLC1A6 MCHR2

1.90e-03477334C0005586
Diseasetriglycerides to total lipids in small VLDL percentage

CETP VEGFB

1.93e-0358332EFO_0022338
Diseaseresponse to opioid

TPRG1 MCHR2

2.13e-0361332EFO_0008541
Diseasefree cholesterol to total lipids in medium LDL percentage

CETP VEGFB

2.27e-0363332EFO_0022283
Diseasealcohol consumption measurement

DNAH2 PKHD1 CACNA1D PAPLN TOPAZ1 MCHR2

2.29e-031242336EFO_0007878
Diseaseage-related macular degeneration, COVID-19

RPL3 CETP

2.72e-0369332EFO_0001365, MONDO_0100096

Protein segments in the cluster

PeptideGeneStartEntry
TLPGIAHLVVETMIV

SLC4A3

391

P48751
TAVGIPEVMSRLEVV

CETP

431

P11597
MLSLLPEVVVLVGVT

CATSPER2

186

Q96P56
IQSIVDGMEPTVTLL

BICDL1

426

Q6ZP65
TTEVPVLVMVTPINE

CDHR4

426

A6H8M9
IIVAIMETNPSILEV

RAB11FIP3

741

O75154
ITVLEMTPVLGTEII

GPHN

331

Q9NQX3
TLMVTGLTPEELAVT

HCFC1

1601

P51610
ELVMFTVGVVVITLP

OR1J2

196

Q8NGS2
DSTVLPGILIEMSEV

MKKS

211

Q9NPJ1
IMGNTTILTVIRTEP

OR51Q1

41

Q8NH59
PELLVTRVVEISIME

PGAP6

181

Q9HCN3
EVIILSEGALVMITP

OR1F1

196

O43749
VVDTVILPSMIGIIC

MCHR2

31

Q969V1
VIPVGTTMDKVVEIL

DCLRE1C

341

Q96SD1
MVIVLTSVGLPTDDI

SLC1A3

451

P43003
MVIVLTSVGLPTEDI

SLC1A6

476

P48664
TSTPTIMDIVVIAGV

GYPC

51

P04921
IAMVVPDSTLIAEII

DNAH2

1926

Q9P225
ETILVELEIMSPLGI

CACNA1D

601

Q01668
RFPIPTEMIVVVVAT

SLC26A9

281

Q7LBE3
EVVEAVTIVETPPMV

RPL3

71

P39023
VTIVETPPMVVVGIV

RPL3

76

P39023
MPVSSLIVGVDLVPI

FTSJ3

66

Q8IY81
PPMTVETISKVIVIE

PKHD1

3651

P08F94
VLTTVMITVVHERVP

SGMS2

91

Q8NHU3
LVITPQIPMVTEEFV

ZNF549

6

Q6P9A3
ILIVPMGATSILIDE

PAPLN

201

O95428
VLTEPILIETYTGLM

TPRG1

241

Q6ZUI0
VTITGETLEIPDTVM

SLC24A5

356

Q71RS6
ETLEIPDTVMGLTLL

SLC24A5

361

Q71RS6
EVVVPLTVELMGTVA

VEGFB

51

P49765
SAVEPTLMVIKEPII

TOPAZ1

576

Q8N9V7
MQVTITLTSPIIREE

ZFR

861

Q96KR1
METVVIVAIGVLATI

TMEM98

1

Q9Y2Y6