Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	SOX9 MYOG TBX21 E2F4 TFAP2C PRDM2 TBX19 KMT2D NFIA NFIB PLSCR2 FOXI1	2.59e-05	560	101	12	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	SOX9 MYOG TBX21 E2F4 TFAP2C PRDM2 TBX19 KMT2D NFIA NFIB PLSCR2 FOXI1	2.88e-05	566	101	12	GO:0001216
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	SOX9 TBX4 DEAF1 MYOG TBX21 POU3F1 E2F4 TFAP2C PRDM2 EOMES TBX19 HOXB9 KMT2D NFIA SAMD11 NFIB PLSCR2 IRX2 FOXI1	7.52e-05	1412	101	19	GO:0000981
GeneOntologyBiologicalProcess	cell fate specification	SOX9 TBX4 TBX21 EOMES TBX19 NFIA NFIB	2.44e-06	123	101	7	GO:0001708
GeneOntologyBiologicalProcess	glial cell fate specification	SOX9 NFIA NFIB	9.37e-06	9	101	3	GO:0021780
GeneOntologyBiologicalProcess	cell fate commitment	SOX9 TBX4 MYOG TBX21 TFAP2C EOMES TBX19 NFIA NFIB	4.26e-05	338	101	9	GO:0045165
GeneOntologyBiologicalProcess	beta-catenin-TCF complex assembly	SOX9 KMT2D	7.10e-05	3	101	2	GO:1904837
Domain	LRRC37AB_C	LRRC37A3 LRRC37A2 LRRC37A	6.49e-07	4	103	3	PF14914
Domain	LRRC37_N	LRRC37A3 LRRC37A2 LRRC37A	6.49e-07	4	103	3	IPR032754
Domain	LRRC37AB_C	LRRC37A3 LRRC37A2 LRRC37A	6.49e-07	4	103	3	IPR029423
Domain	LRRC37	LRRC37A3 LRRC37A2 LRRC37A	6.49e-07	4	103	3	PF15779
Domain	LRRC37A/B-like	LRRC37A3 LRRC37A2 LRRC37A	6.49e-07	4	103	3	IPR015753
Domain	TF_T-box	TBX4 TBX21 EOMES TBX19	1.96e-06	17	103	4	IPR001699
Domain	TBOX	TBX4 TBX21 EOMES TBX19	1.96e-06	17	103	4	SM00425
Domain	TF_T-box_CS	TBX4 TBX21 EOMES TBX19	1.96e-06	17	103	4	IPR018186
Domain	-	TBX4 TBX21 EOMES TBX19	1.96e-06	17	103	4	2.60.40.820
Domain	TBOX_3	TBX4 TBX21 EOMES TBX19	1.96e-06	17	103	4	PS50252
Domain	T-box	TBX4 TBX21 EOMES TBX19	1.96e-06	17	103	4	PF00907
Domain	TBOX_1	TBX4 TBX21 EOMES TBX19	1.96e-06	17	103	4	PS01283
Domain	TBOX_2	TBX4 TBX21 EOMES TBX19	1.96e-06	17	103	4	PS01264
Domain	SUSHI	CD248 CFHR5 APOH CSMD2 CSMD3	1.41e-05	56	103	5	PS50923
Domain	Sushi_SCR_CCP_dom	CD248 CFHR5 APOH CSMD2 CSMD3	1.54e-05	57	103	5	IPR000436
Domain	NfI_DNAbd_pre-N	NFIA NFIB	1.79e-04	4	103	2	PF10524
Domain	CTF_NFI	NFIA NFIB	1.79e-04	4	103	2	PF00859
Domain	CTF_NFI_1	NFIA NFIB	1.79e-04	4	103	2	PS00349
Domain	CTF/NFI	NFIA NFIB	1.79e-04	4	103	2	IPR000647
Domain	CTF_NFI_2	NFIA NFIB	1.79e-04	4	103	2	PS51080
Domain	CTF/NFI_DNA-bd_N	NFIA NFIB	1.79e-04	4	103	2	IPR019548
Domain	CTF/NFI_DNA-bd_CS	NFIA NFIB	1.79e-04	4	103	2	IPR019739
Domain	CTF/NFI_DNA-bd-dom	NFIA NFIB	1.79e-04	4	103	2	IPR020604
Domain	Sushi	CFHR5 APOH CSMD2 CSMD3	1.93e-04	52	103	4	PF00084
Domain	p53-like_TF_DNA-bd	TBX4 TBX21 EOMES TBX19	2.08e-04	53	103	4	IPR008967
Domain	CCP	CFHR5 APOH CSMD2 CSMD3	2.23e-04	54	103	4	SM00032
Domain	TF_Brachyury	TBX4 TBX19	4.45e-04	6	103	2	IPR002070
Domain	Shisa	SHISA9 SHISA3	1.06e-03	9	103	2	PF13908
Domain	Shisa	SHISA9 SHISA3	1.06e-03	9	103	2	IPR026910
Domain	MAD_homology1_Dwarfin-type	NFIA NFIB	1.92e-03	12	103	2	IPR003619
Domain	DWA	NFIA NFIB	1.92e-03	12	103	2	SM00523
Domain	MH1	NFIA NFIB	1.92e-03	12	103	2	PF03165
Domain	ATPase_dyneun-rel_AAA	MDN1 DNAH9	2.62e-03	14	103	2	IPR011704
Domain	AAA_5	MDN1 DNAH9	2.62e-03	14	103	2	PF07728
Pubmed	A census of human transcription factors: function, expression and evolution.	SOX9 RC3H2 TBX4 DEAF1 MYOG TBX21 POU3F1 E2F4 TFAP2C PRDM2 EOMES TBX19 HOXB9 KMT2D NFIA NFIB IRX2 FOXI1	2.56e-10	908	105	18	19274049
Pubmed	Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.	LRRC37A3 LRRC37A2 LRRC37A	1.07e-07	4	105	3	22419166
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	SOX9 MYOG TBX21 POU3F1 E2F4 TFAP2C EOMES TBX19 HOXB9 NFIB FOXI1	8.21e-07	544	105	11	28473536
Pubmed	Dentate gyrus morphogenesis is regulated by β-catenin function in hem-derived fimbrial glia.	SOX9 EOMES NFIA NFIB	9.45e-07	25	105	4	36196585
Pubmed	The role of a lymphoid-restricted, Grb2-like SH3-SH2-SH3 protein in T cell receptor signaling.	SHC1 LAT FYN	2.22e-06	9	105	3	8995379
Pubmed	NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1.	POU3F1 EOMES NFIA NFIB	2.64e-06	32	105	4	20610746
Pubmed	Tbx3 controls the fate of hepatic progenitor cells in liver development by suppressing p19ARF expression.	TBX4 TBX21 EOMES TBX19	3.00e-06	33	105	4	18356246
Pubmed	Evolutionary dynamism of the primate LRRC37 gene family.	LRRC37A3 LRRC37A2 LRRC37A	3.16e-06	10	105	3	23064749
Pubmed	Tyrosine phosphorylation of Cbl upon epidermal growth factor (EGF) stimulation and its association with EGF receptor and downstream signaling proteins.	SHC1 CRKL FYN	3.16e-06	10	105	3	8662998
Pubmed	Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC.	CYP4V2 DEAF1 CD248 WDR7 BTAF1 CSMD3 CRKL EIF4E2	3.17e-06	293	105	8	31741433
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	WDR7 AVL9 MYO10 STXBP5 HEATR5A CSMD3 EPG5 RUSC2 OTUD4	4.21e-06	407	105	9	12693553
Pubmed	Nfix regulates fetal-specific transcription in developing skeletal muscle.	MYOG NFIA NFIB	4.33e-06	11	105	3	20178747
Pubmed	Association study of detoxification genes in age related macular degeneration.	CYP2E1 CAT SOD2	5.77e-06	12	105	3	15774926
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	FLNB ILF3 DHX15 FAT2 KMT2D MDN1 MTREX	7.42e-06	234	105	7	36243803
Pubmed	Transcriptional regulation of Nfix by NFIB drives astrocytic maturation within the developing spinal cord.	SOX9 NFIA NFIB	7.48e-06	13	105	3	29106906
Pubmed	Genetic Variants in the Manganese Superoxide Dismutase 2 Gene and in the Catalase Gene are not Associated With Alcoholic Chronic Pancreatitis.	CAT SOD2	9.03e-06	2	105	2	28655148
Pubmed	Inflammation programs self-reactive CD8+ T cells to acquire T-box-mediated effector function but does not prevent deletional tolerance.	TBX21 EOMES	9.03e-06	2	105	2	24823810
Pubmed	Differential transcription of Eomes and T-bet during maturation of mouse uterine natural killer cells.	TBX21 EOMES	9.03e-06	2	105	2	16204645
Pubmed	Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin.	TBX21 EOMES	9.03e-06	2	105	2	16273099
Pubmed	Nuclear Factor IA Is Down-regulated in Muscle-invasive and High-grade Bladder Cancers.	NFIA NFIB	9.03e-06	2	105	2	34969759
Pubmed	T-BET and EOMES Accelerate and Enhance Functional Differentiation of Human Natural Killer Cells.	TBX21 EOMES	9.03e-06	2	105	2	34630413
Pubmed	Cutting edge: The transcription factor eomesodermin enables CD8+ T cells to compete for the memory cell niche.	TBX21 EOMES	9.03e-06	2	105	2	20935204
Pubmed	Progenitor and terminal subsets of CD8+ T cells cooperate to contain chronic viral infection.	TBX21 EOMES	9.03e-06	2	105	2	23197535
Pubmed	Eomes+T-betlow CD8+ T Cells Are Functionally Impaired and Are Associated with Poor Clinical Outcome in Patients with Acute Myeloid Leukemia.	TBX21 EOMES	9.03e-06	2	105	2	30709927
Pubmed	MnSOD and CAT polymorphisms modulate the effect of the Mediterranean diet on breast cancer risk among Greek-Cypriot women.	CAT SOD2	9.03e-06	2	105	2	26130326
Pubmed	Adenovirus-mediated overexpression of catalase in the cytosolic or mitochondrial compartment protects against toxicity caused by glutathione depletion in HepG2 cells expressing CYP2E1.	CYP2E1 CAT	9.03e-06	2	105	2	11907164
Pubmed	IL-12 Influence mTOR to Modulate CD8+ T Cells Differentiation through T-bet and Eomesodermin in Response to Invasive Pulmonary Aspergillosis.	TBX21 EOMES	9.03e-06	2	105	2	28924369
Pubmed	Enhanced activity of superoxide dismutase is a common response to dietary and genetically induced increased cholesterol levels.	NPC1 SOD2	9.03e-06	2	105	2	30118401
Pubmed	Characterization of eomesodermin and T-bet expression by allostimulated CD8+ T cells of healthy volunteers and kidney transplant patients in relation to graft outcome.	TBX21 EOMES	9.03e-06	2	105	2	30246373
Pubmed	The low EOMES/TBX21 molecular phenotype in multiple sclerosis reflects CD56+ cell dysregulation and is affected by immunomodulatory therapies.	TBX21 EOMES	9.03e-06	2	105	2	26762769
Pubmed	Mitochondrial DNA (mtDNA) haplogroups and serum levels of anti-oxidant enzymes in patients with osteoarthritis.	CAT SOD2	9.03e-06	2	105	2	22108257
Pubmed	The autoimmune disease-associated transcription factors EOMES and TBX21 are dysregulated in multiple sclerosis and define a molecular subtype of disease.	TBX21 EOMES	9.03e-06	2	105	2	24495857
Pubmed	Eomes is sufficient to regulate IL-10 expression and cytotoxic effector molecules in murine CD4+ T cells.	TBX21 EOMES	9.03e-06	2	105	2	36756120
Pubmed	T-bet and Eomes govern differentiation and function of mouse and human NK cells and ILC1.	TBX21 EOMES	9.03e-06	2	105	2	29424438
Pubmed	Clinical variables and ethnicity may influenced by polymorphism of CAT -262C/T and MnSOD 47C/T antioxidant enzymes in Algerian type1 diabetes without complications.	CAT SOD2	9.03e-06	2	105	2	29859283
Pubmed	Expression of NFIA and NFIB within the murine spinal cord.	NFIA NFIB	9.03e-06	2	105	2	32068188
Pubmed	Genetic variations of superoxide dismutase 2 and cytochrome P450 2E1 in non-alcoholic steatohepatitis.	CYP2E1 SOD2	9.03e-06	2	105	2	24649902
Pubmed	Polymorphisms and functional activity in superoxide dismutase and catalase genes in smokers with COPD.	CAT SOD2	9.03e-06	2	105	2	17567676
Pubmed	Epigenetic and transcriptional programs lead to default IFN-gamma production by gammadelta T cells.	TBX21 EOMES	9.03e-06	2	105	2	17312115
Pubmed	Control of effector CD8+ T cell function by the transcription factor Eomesodermin.	TBX21 EOMES	9.03e-06	2	105	2	14605368
Pubmed	Pre-treatment with N-acetylcysteine upregulates superoxide dismutase 2 and catalase genes in cadmium-induced oxidative stress in the chick omphalocele model.	CAT SOD2	9.03e-06	2	105	2	21069346
Pubmed	Antioxidant enzymes mediate survival of breast cancer cells deprived of extracellular matrix.	CAT SOD2	9.03e-06	2	105	2	23771908
Pubmed	Nuclear Factor I A and Nuclear Factor I B Are Jointly Required for Mouse Postnatal Neural Stem Cell Self-Renewal.	NFIA NFIB	9.03e-06	2	105	2	38366751
Pubmed	Eomes cannot replace its paralog T-bet during expansion and differentiation of CD8 effector T cells.	TBX21 EOMES	9.03e-06	2	105	2	32991634
Pubmed	NK Cell Functional Impairment after Allogeneic Hematopoietic Stem Cell Transplantation Is Associated with Reduced Levels of T-bet and Eomesodermin.	TBX21 EOMES	9.03e-06	2	105	2	26438526
Pubmed	Differential localization of T-bet and Eomes in CD8 T cell memory populations.	TBX21 EOMES	9.03e-06	2	105	2	23455505
Pubmed	The association between adult asthma and superoxide dismutase and catalase gene activity.	CAT SOD2	9.03e-06	2	105	2	21829032
Pubmed	T-bet and Eomes are differentially linked to the exhausted phenotype of CD8+ T cells in HIV infection.	TBX21 EOMES	9.03e-06	2	105	2	25032686
Pubmed	Evaluation of Mn-superoxide dismutase and catalase gene expression in childhood obesity: its association with insulin resistance.	CAT SOD2	9.03e-06	2	105	2	29953407
Pubmed	Mest/Peg1 inhibits Wnt signalling through regulation of LRP6 glycosylation.	MEST LRP6	9.03e-06	2	105	2	21375506
Pubmed	Chronic HIV infection affects the expression of the 2 transcription factors required for CD8 T-cell differentiation into cytolytic effectors.	TBX21 EOMES	9.03e-06	2	105	2	22490682
Pubmed	T-BET and EOMES sustain mature human NK cell identity and antitumor function.	TBX21 EOMES	9.03e-06	2	105	2	37279078
Pubmed	Bona Fide Th17 Cells without Th1 Functional Plasticity Protect against Influenza.	TBX21 EOMES	9.03e-06	2	105	2	35338093
Pubmed	Genetic variability in CYP2E1 and catalase gene among currently and formerly alcohol-dependent male subjects.	CYP2E1 CAT	9.03e-06	2	105	2	25514903
Pubmed	Prognostic significance of NFIA and NFIB in esophageal squamous carcinoma and esophagogastric junction adenocarcinoma.	NFIA NFIB	9.03e-06	2	105	2	29577671
Pubmed	MnSOD and catalase transgenes demonstrate that protection of islets from oxidative stress does not alter cytokine toxicity.	CAT SOD2	9.03e-06	2	105	2	15855331
Pubmed	Eomesodermin and T-bet mark developmentally distinct human natural killer cells.	TBX21 EOMES	9.03e-06	2	105	2	28289707
Pubmed	Nfib promotes chondrocyte proliferation and inhibits differentiation by mildly regulating Sox9 and its downstream genes.	SOX9 NFIB	9.03e-06	2	105	2	34651294
Pubmed	The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation.	TBX21 EOMES	9.03e-06	2	105	2	22261438
Pubmed	SOX9/NFIA promotes human ovarian cancer metastasis through the Wnt/β-catenin signaling pathway.	SOX9 NFIA	9.03e-06	2	105	2	37315400
Pubmed	Increased expression of catalase and superoxide dismutase 2 reduces cone cell death in retinitis pigmentosa.	CAT SOD2	9.03e-06	2	105	2	19293779
Pubmed	Transcription factors NFIA and NFIB induce cellular differentiation in high-grade astrocytoma.	NFIA NFIB	9.03e-06	2	105	2	31760595
Pubmed	The KMT2D Kabuki syndrome histone methylase controls neural crest cell differentiation and facial morphology.	SOX9 KMT2D TNN	9.50e-06	14	105	3	32541010
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	DSC2 ANPEP APOH ITIH3 FAT2 PTPRS TNN	1.36e-05	257	105	7	16335952
Pubmed	New semidominant mutations that affect mouse development.	SOX9 MYOG LRP6	1.46e-05	16	105	3	15384171
Pubmed	Filamin A- and formin 2-dependent endocytosis regulates proliferation via the canonical Wnt pathway.	FLNB EOMES LRP6	1.46e-05	16	105	3	27789627
Pubmed	Nuclear factor one B regulates neural stem cell differentiation and axonal projection of corticofugal neurons.	EOMES NFIA NFIB	1.76e-05	17	105	3	23749646
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	FLNB ILF3 DSC2 DHX15 AMOT MTREX SEC23B	2.06e-05	274	105	7	34244482
Pubmed	NFIX regulates neural progenitor cell differentiation during hippocampal morphogenesis.	SOX9 POU3F1 EOMES	2.11e-05	18	105	3	23042739
Pubmed	Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs.	SOX9 TFAP2C EOMES	2.50e-05	19	105	3	35988542
Pubmed	The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.	SOX9 MYOG POU3F1 EOMES NFIA IRX2	2.60e-05	191	105	6	24146773
Pubmed	Identification of two new members of the CSMD gene family.	CSMD2 CSMD3	2.70e-05	3	105	2	12906867
Pubmed	Polymorphisms in oxidative stress-related genes are not associated with prostate cancer risk in heavy smokers.	CAT SOD2	2.70e-05	3	105	2	17548672
Pubmed	[Role of transcription factor T-bet and Eomes in IFN-gamma secretion of different human T cell subsets].	TBX21 EOMES	2.70e-05	3	105	2	20056084
Pubmed	Manganese superoxide dismutase Ile58Thr, catalase C-262T and myeloperoxidase G-463A gene polymorphisms in patients with prostate cancer: relation to advanced and metastatic disease.	CAT SOD2	2.70e-05	3	105	2	23773345
Pubmed	Age-dependent changes in the expression of superoxide dismutases and catalase are associated with ultrastructural modifications in human granulosa cells.	CAT SOD2	2.70e-05	3	105	2	17005595
Pubmed	The association between polymorphisms in prooxidant or antioxidant enzymes (myeloperoxidase, SOD2, and CAT) and genes and prostate cancer risk in the Chinese population of Han nationality.	CAT SOD2	2.70e-05	3	105	2	22959522
Pubmed	T-bet and eomesodermin play critical roles in directing T cell differentiation to Th1 versus Th17.	TBX21 EOMES	2.70e-05	3	105	2	19050290
Pubmed	Analysis of Serum Cytokines and Single-Nucleotide Polymorphisms of SOD1, SOD2, and CAT in Erysipelas Patients.	CAT SOD2	2.70e-05	3	105	2	28512644
Pubmed	Pseudoxanthoma elasticum: genetic variations in antioxidant genes are risk factors for early disease onset.	CAT SOD2	2.70e-05	3	105	2	17693525
Pubmed	MnSOD, CAT and GPx-3 genetic polymorphisms in coronary artery disease.	CAT SOD2	2.70e-05	3	105	2	30600457
Pubmed	Neocortical Sox9+ radial glia generate glutamatergic neurons for all layers, but lack discernible evidence of early laminar fate restriction.	SOX9 EOMES	2.70e-05	3	105	2	28814327
Pubmed	Oxidative response gene polymorphisms and risk of adult brain tumors.	CAT SOD2	2.70e-05	3	105	2	18682580
Pubmed	Association between Polymorphisms of Antioxidant Gene (MnSOD, CAT, and GPx1) and Risk of Coronary Artery Disease.	CAT SOD2	2.70e-05	3	105	2	30225256
Pubmed	Cutting Edge: Divergent Requirement of T-Box Transcription Factors in Effector and Memory NK Cells.	TBX21 EOMES	2.70e-05	3	105	2	29440505
Pubmed	Variability in a three-generation family with Pierre Robin sequence, acampomelic campomelic dysplasia, and intellectual disability due to a novel ∼1 Mb deletion upstream of SOX9, and including KCNJ2 and KCNJ16.	SOX9 KCNJ16	2.70e-05	3	105	2	26663529
Pubmed	The effect of hydrogen peroxide-induced oxidative stress on leukocytes depends on age and physical training in healthy human subjects carrying the same genotypes of antioxidant enzymes' gene polymorphisms.	CAT SOD2	2.70e-05	3	105	2	20878976
Pubmed	Implications of antioxidant enzymes in human gastric neoplasms.	CAT SOD2	2.70e-05	3	105	2	19787204
Pubmed	Formation of new chromatin domains determines pathogenicity of genomic duplications.	SOX9 KCNJ16	2.70e-05	3	105	2	27706140
Pubmed	Single-Cell RNA-Seq Analysis of Retinal Development Identifies NFI Factors as Regulating Mitotic Exit and Late-Born Cell Specification.	NFIA NFIB	2.70e-05	3	105	2	31128945
Pubmed	Manganese superoxide dismutase (SOD2/MnSOD)/catalase and SOD2/GPx1 ratios as biomarkers for tumor progression and metastasis in prostate, colon, and lung cancer.	CAT SOD2	2.70e-05	3	105	2	25866291
Pubmed	Mutation in EGFP domain of LDL receptor-related protein 6 impairs cellular LDL clearance.	NPC1 LRP6	2.70e-05	3	105	2	18948618
Pubmed	Sirtuin 1 attenuates oxidative stress via upregulation of superoxide dismutase 2 and catalase in astrocytes.	CAT SOD2	2.70e-05	3	105	2	24565075
Pubmed	Hepatoprotective effects of chestnut (Castanea crenata) inner shell extract against chronic ethanol-induced oxidative stress in C57BL/6 mice.	CYP2E1 CAT	2.70e-05	3	105	2	21457746
Pubmed	Superoxide Dismutase and Catalase Genotypes in Pediatric Migraine Patients.	CAT SOD2	2.70e-05	3	105	2	25818327
Pubmed	Myeloperoxidase and superoxide dismutase 2 polymorphisms comodulate the risk of hepatocellular carcinoma and death in alcoholic cirrhosis.	CAT SOD2	2.70e-05	3	105	2	19731237
Pubmed	The mTOR kinase determines effector versus memory CD8+ T cell fate by regulating the expression of transcription factors T-bet and Eomesodermin.	TBX21 EOMES	2.70e-05	3	105	2	20060330
Pubmed	Antioxidant proteins and reactive oxygen species are decreased in a murine epidermal side population with stem cell-like characteristics.	CAT SOD2	2.70e-05	3	105	2	21347610
Pubmed	The CAT-262 C>T, MnSOD Ala16Val, GPX1 Pro198Leu Polymorphisms Related to Oxidative Stress and the Presence of Gastric Lesions.	CAT SOD2	2.70e-05	3	105	2	30574618
Pubmed	Variation of the genes encoding antioxidant enzymes SOD2 (rs4880), GPX1 (rs1050450), and CAT (rs1001179) and susceptibility to male infertility: a genetic association study and in silico analysis.	CAT SOD2	2.70e-05	3	105	2	37405601
Cytoband	Ensembl 112 genes in cytogenetic band chr17q24	SOX9 LRRC37A3 APOH KCNJ16	7.91e-05	98	105	4	chr17q24
GeneFamily	T-boxes	TBX4 TBX21 EOMES TBX19	6.78e-07	18	72	4	766
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	CFHR5 APOH CSMD2 CSMD3	7.79e-05	57	72	4	1179
GeneFamily	Shisa family members	SHISA9 SHISA3	4.31e-04	8	72	2	742
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRGL2B	SOX9 LRRC37A3 RBMS2 HEATR5A CSMD2 CSMD3 FAT2 NFIA NFIB IRX2 SHISA3	1.56e-06	439	105	11	M39054
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	SOX9 FLNB WDR7 AVL9 MYO10 SPART BTAF1 DHX15 MDN1 NFIB OTUD4 N4BP2L2 MTREX FYN	8.25e-06	856	105	14	M4500
Coexpression	ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN	THSD4 SOX9 LRRC37A3 MYO10 STXBP5 CAT HEATR5A CSMD3 WDFY4 MEST FAT2 OTUD4 PLSCR2 FYN	1.03e-05	873	105	14	M16009
Coexpression	AIZARANI_LIVER_C7_EPCAM_POS_BILE_DUCT_CELLS_2	THSD4 SOX9 ANPEP MYO10 LGALS4 NFIB KCNJ16	2.94e-05	219	105	7	M39111
ToppCell	hematopoetic_progenitors-CD34+_MEP_1\|hematopoetic_progenitors / Lineage and Cell class	STXBP5 CPA3 MEST ACSM3 LAT SDCBP SOD2	4.39e-07	197	105	7	6172a1b98ff840d9174b1ab20ba0c202a7ef87af
ToppCell	control-Epithelial-Secretory\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	FLNB ANPEP FAT2 NFIA PTPRS NFIB N4BP2L2	4.70e-07	199	105	7	3d01f90ffd271ca00129192787e4921bdca7e01e
ToppCell	droplet-Liver-Hepatocytes-24m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP2E1 CAT APOH ITIH3 LGALS4 HECTD2	1.65e-06	152	105	6	c21e2152b0130485659051d8fb7fb4589d1ec997
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 CSMD2 ITIH3 CELF3 CFAP221 RBM24	3.25e-06	171	105	6	4ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCell	Tuft-tuft-4\|World / Class top	FLNB WDR7 SAMD9L MDN1 OASL SLC6A14	3.60e-06	174	105	6	d6f306ebf66061bf9e9742000bfedce12d277452
ToppCell	droplet-Spleen-nan-21m-Lymphocytic-mature_NK_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A TBX21 DACT2 EOMES LAT FYN	3.97e-06	177	105	6	1381aeb48a4133af060a9e2e7ce08b8b058e12c1
ToppCell	facs-Marrow-T-cells-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPC1 FLNB CYP2E1 CPA3 PTPRS FYN	4.51e-06	181	105	6	7286700396676fdc41d9723979b8b408177aceb9
ToppCell	5'-Adult-LargeIntestine-Epithelial-Tuft-related-Microfold_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DSC2 DACT2 GPRC5C ITIH3 LGALS4 ACSM3	4.51e-06	181	105	6	4d7d367f4ed390908888391335c714a22b5a75c4
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-Tuft-related-Microfold_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX9 DSC2 ITIH3 LGALS4 HOXB9 SLC6A14	4.81e-06	183	105	6	9a2cd63af5f492d46ce80ca1536312e8ac0e7df4
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX9 DSC2 GPRC5C LGALS4 HOXB9 SLC6A14	4.81e-06	183	105	6	263937906ddabc798bbe60f0da28ba859a5c72e2
ToppCell	droplet-Marrow-nan-21m-Hematologic-hematopoietic_precursor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX21 EOMES SHISA9 LAT PLSCR2 FYN	4.96e-06	184	105	6	7e129862f8d2353387999e633725325c4d8cb42e
ToppCell	background-Cholangiocytes\|World / Sample and Cell Type and Tumor Cluster (all cells)	THSD4 SOX9 CYP2E1 LGALS4 NFIB KCNJ16	6.14e-06	191	105	6	99aa8d685767a72bef9f05e7cc8913126a048c39
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-IPC_like-IPCs\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	MYO10 TFAP2C EOMES MEST NFIA FYN	6.52e-06	193	105	6	2088f1d210c73f74685492c63065c62ac3f553e9
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-IPC_like\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	MYO10 TFAP2C EOMES MEST NFIA FYN	6.52e-06	193	105	6	f24bae40f5cbcfece04fbefe4e3de1b88ac90de4
ToppCell	NS-critical-d_07-13-Epithelial-Secretory\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FLNB GALE GPRC5C NFIA PTPRS NFIB	6.72e-06	194	105	6	2172d951896265243d14996eacce5aab5e14e26e
ToppCell	droplet-Limb_Muscle-MUSCLE\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO10 MYOG PRDM2 MEST SAMD9L N4BP2L2	6.72e-06	194	105	6	e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	CD248 TBX21 EOMES LAT OASL FYN	6.72e-06	194	105	6	68e9ad254fe94e2f59cf5c2b2ea3e1245cb85104
ToppCell	facs-Skin-Anagen-3m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX9 FLNB SPART HOXB9 NFIB SDCBP	6.72e-06	194	105	6	5d30d3d41d5f19cdf3077cc609aa2738762cb8c5
ToppCell	-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	CD248 TBX21 CPA3 EOMES SAMD11 FYN	6.92e-06	195	105	6	e5b0afbea85575851cf9eb50a9ac42c67bbf3d7c
ToppCell	critical-Epithelial-Secretory\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	FLNB GALE GPRC5C NFIA NFIB SLC6A14	7.12e-06	196	105	6	7da687eb983a54c28ee990424cc52e01caf5f4aa
ToppCell	distal-Hematologic-Platelet/Megakaryocyte\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SOX9 CFAP107 SHISA9 PTPRN KCNJ16 DNAH9	7.33e-06	197	105	6	e28b1b154d9588dce07c123b36f7f01fa90a5fc1
ToppCell	NS-control-d_0-4-Epithelial-Secretory\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FLNB ANPEP FAT2 NFIA PTPRS NFIB	7.77e-06	199	105	6	32bdfff40fd442b88489c8b0f79af3927a51a03c
ToppCell	18-Distal-Mesenchymal\|Distal / Age, Tissue, Lineage and Cell class	CD248 MEST NFIA SAMD11 NFIB SHISA3	7.77e-06	199	105	6	d65150d2e24c40aa82712e7f034f6772102bd293
ToppCell	COVID-19-COVID-19_Mild-Myeloid-pDC\|COVID-19_Mild / Disease, condition lineage and cell class	NPC1 FLNB CAT GPRC5C WDFY4 PTPRS	7.77e-06	199	105	6	9de61e5189d907cc969ac3043d68204f70acc0bf
ToppCell	control-Epithelial-Secretory\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	FLNB ANPEP FAT2 NFIA PTPRS NFIB	7.77e-06	199	105	6	262e5b8a52c8ddb0b47048c786e8bdb7158e1b9a
ToppCell	mLN-(1)_T_cell-(10)_CD8_T\|mLN / shred on region, Cell_type, and subtype	CD248 TBX21 EOMES LAT OASL FYN	7.99e-06	200	105	6	6f02ba3a76e8aa3083efea9cb4ee587799c61fda
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-OPC_related-Oligodendrocyte/OPC\|3m / Sample Type, Dataset, Time_group, and Cell type.	MYO10 MYOG TFAP2C EOMES MEST NFIA	7.99e-06	200	105	6	7557ea33c3d080d0fa4ca0c2703279932d01e6d0
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Macroglial-Astrocyte\|10w / Sample Type, Dataset, Time_group, and Cell type.	SOX9 MYO10 MEST NFIA NFIB SDCBP	7.99e-06	200	105	6	75f5ea38fbd341b80a8058077a04447f0e0eea28
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-OPC_related\|3m / Sample Type, Dataset, Time_group, and Cell type.	MYO10 MYOG TFAP2C EOMES MEST NFIA	7.99e-06	200	105	6	3dcaeb9f1e387784c299bfe0da1516598f82edf5
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THSD4 CD248 MEST NFIA NFIB SHISA3	7.99e-06	200	105	6	3dacd0afe69bc16bb33336ea9ea99a9cd47731d9
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Macroglial\|10w / Sample Type, Dataset, Time_group, and Cell type.	SOX9 MYO10 SPART MEST NFIA SDCBP	7.99e-06	200	105	6	bda719369aa199902789061e223b129f70a1317a
ToppCell	mLN-T_cell-CD8_T\|mLN / Region, Cell class and subclass	CD248 TBX21 EOMES LAT OASL FYN	7.99e-06	200	105	6	a221213f9245297a5d6196564c1043f8c17eb857
ToppCell	(5)_Fibroblast-H\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	CD248 MEST PTPRS SAMD11 NFIB SHISA3	7.99e-06	200	105	6	94e77a1082ade6fad93a37168e037af8aefe7ff4
ToppCell	TCGA-Breast-Metastatic-Breast_Carcinoma\|TCGA-Breast / Sample_Type by Project: Shred V9	CYP2E1 CFHR5 APOH ITIH3 SHISA3	2.75e-05	149	105	5	c7dc495141cd921b6b6f291a68851b7b807d0d0a
ToppCell	TCGA-Breast-Metastatic-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma\|TCGA-Breast / Sample_Type by Project: Shred V9	CYP2E1 CFHR5 APOH ITIH3 SHISA3	2.75e-05	149	105	5	2e9b898f3df22f8e872f2c278eff454c39e55b3b
ToppCell	TCGA-Breast-Metastatic\|TCGA-Breast / Sample_Type by Project: Shred V9	CYP2E1 CFHR5 APOH ITIH3 SHISA3	2.75e-05	149	105	5	144ac2c458209ce510674bc2f83eb4c8e4d3c953
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic-NK_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A TBX21 EOMES SAMD11 FYN	3.13e-05	153	105	5	2a94092937267cd2282452dfde3d328d763d4294
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic-Natural_Killer\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A TBX21 EOMES SAMD11 FYN	3.13e-05	153	105	5	ad33c81fe6ac10e7c263d42541aae0d796923bad
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-SMG_basal_1\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SOX9 DACT2 IRX2 SLC6A14 FOXI1	3.65e-05	158	105	5	adad97e6cf479d42791c5ba9cbc5f15f469322bf
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP2E1 CAT ACSM3 PLSCR2 SOD2	3.76e-05	159	105	5	c34a7d227dbda2d7c76f937e1a58552b14bd40b5
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	CSMD2 CSMD3 USH2A DNAH9 IQCM	3.76e-05	159	105	5	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	facs-BAT-Fat-3m-Lymphocytic-NK_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX21 EOMES LAT FYN CLCF1	4.36e-05	164	105	5	cbdb7e893cb3959b9920c0c7c535ace03a5f4986
ToppCell	Tuft-tuft-1\|World / Class top	SOX9 TFAP2C PLSCR2 SEC23B SLC6A14	4.88e-05	168	105	5	8ddc2ec483ed2c6c0fb2ae521c6861ceb6d32e34
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANPEP CD248 GPRC5C TNN RBM24	5.61e-05	173	105	5	2415b6ff49f334da570577d4e93484d024a3dbd5
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANPEP CD248 GPRC5C TNN RBM24	5.61e-05	173	105	5	2acd0693a2dfe04e3c1b2125ea63efe92d13150b
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC22 SHC1 GPRC5C APOH MDN1	5.93e-05	175	105	5	dbd9dac129fb6ae5f55e7b96d04b37585458dc4a
ToppCell	droplet-Mammary_Gland-nan-21m-Endothelial-basal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POU3F1 STARD6 HOXB9 FAT2 HECTD2	6.09e-05	176	105	5	27e5115fae5f0f63b333bc99fbf6a6d4c9182c46
ToppCell	droplet-Spleen-SPLEEN-30m-Lymphocytic-mature_NK_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A TBX21 EOMES LAT FYN	6.26e-05	177	105	5	52402ff6299210c46fd9dee3cef203c0eda7a98a
ToppCell	droplet-Spleen-nan-3m-Lymphocytic-mature_NK_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A TBX21 EOMES LAT FYN	6.26e-05	177	105	5	dba8b30a311051c22ca5f77697f5dbf9423c3ba0
ToppCell	3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Mast_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	STXBP5 CPA3 WDFY4 LAT OASL	6.26e-05	177	105	5	15553c7cd7826c80086daa76af4224f32dde53a6
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANPEP CD248 GPRC5C TNN CFAP221	6.43e-05	178	105	5	7467e5ab2fcb39cc4a2c7dd69722c91def3b6aea
ToppCell	ILEUM-non-inflamed-(7)_Lymphatics\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PDE2A SHC1 NFIA NFIB AMOT	6.60e-05	179	105	5	99777a8931356d1206b8ab22aaa1b1d5a600b809
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNB ANPEP CD248 DACT2 CRKL	6.77e-05	180	105	5	c4068fe47408cfd899131a85fa4b7e5908926f94
ToppCell	droplet-Kidney\|droplet / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP2E1 CAT GPRC5C KCNJ16 PLSCR2	6.77e-05	180	105	5	7e5f497699876ac8e1ce780626c6f5a1f6f5f079
ToppCell	facs-Spleen-nan-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A TBX21 EOMES LAT FYN	6.77e-05	180	105	5	407fd8f61a757626e082b6e2eefd3a33276e6b71
ToppCell	facs-Liver-Hepatocytes-24m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4V2 DSC2 ANPEP DACT2 GPRC5C	7.32e-05	183	105	5	d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCell	Mesenchymal_cells-Osteoblasts\|Mesenchymal_cells / Lineage and Cell class	GALE MYO10 GPRC5C HOXB9 PTPRS	7.32e-05	183	105	5	d6b52d52fe9a7a6c798947f05420d79fe12e4662
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_3\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	TBX4 CD248 HOXB9 NFIB CLCF1	7.32e-05	183	105	5	f4ea7113ce9099222743d9ff02388d3d8a9e987b
ToppCell	droplet-Spleen-SPLEEN-1m-Lymphocytic-mature_NK_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A TBX21 EOMES LAT FYN	7.51e-05	184	105	5	8095be57ed189763b5be039f330149a41e5b406a
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPART CSMD2 RUSC2 PTPRS SOD2	7.71e-05	185	105	5	9faa35ceb89ccd2979072286f063687c9f846ce3
ToppCell	normal_Lymph_Node-T/NK_cells-Cytotoxic_CD8+_T\|normal_Lymph_Node / Location, Cell class and cell subclass	TBX21 EOMES HOXB9 OASL FYN	7.71e-05	185	105	5	9f330f254ee3ce47e1dd1155f2d16fa262ca89b2
ToppCell	droplet-Fat-Scat-21m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX9 DSC2 TFAP2C IRX2 FOXI1	7.91e-05	186	105	5	59710cff3f6f7c318ee2524b44c1a909f312c25e
ToppCell	droplet-Fat-Scat-21m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX9 DSC2 TFAP2C IRX2 FOXI1	7.91e-05	186	105	5	de88fafac51049ec1920695844d8ce8057940272
ToppCell	droplet-Fat-Scat-21m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX9 DSC2 TFAP2C IRX2 FOXI1	7.91e-05	186	105	5	7ff73ab8fed5da779ee9c7bd2e14a8363edb7509
ToppCell	Control-Lymphocyte-T_NK-CD8_TEM\|Control / Disease, Lineage and Cell Type	TBX21 EOMES LAT OASL FYN	8.11e-05	187	105	5	7fdff970a9397305d0b8194c00a043cc69dcca12
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYP4V2 SHISA9 NFIB AMOT CLCF1	8.11e-05	187	105	5	f5a202d5f8eb57b57d80815ce98774e04c387383
ToppCell	Frontal_cortex-Endothelial\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	ANPEP CD248 SHC1 SAMD9L PLSCR2	8.32e-05	188	105	5	a43392dbd10fc7dbfb31be39b8af8a7ea121c894
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 SHISA9 CFAP221 KCNJ16 IRX2	8.32e-05	188	105	5	2ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCell	facs-MAT-Fat-3m\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAT RUSC2 LRP6 MTREX SHISA3	8.32e-05	188	105	5	7da9750255efbc5cf9aed7e3105a337fac63b9f0
ToppCell	droplet-Lung-nan-18m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD4 ANPEP FAT2 IRX2 SLC6A14	8.53e-05	189	105	5	ca657353f2b649530809c0bc057e448adc511ec1
ToppCell	droplet-Lung-nan-18m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD4 ANPEP FAT2 IRX2 SLC6A14	8.53e-05	189	105	5	e5325f1c7430b574947f8ee67e425455b60dc518
ToppCell	E18.5-samps-Mesenchymal\|E18.5-samps / Age Group, Lineage, Cell class and subclass	TBX4 CD248 NFIA PTPRS NFIB	8.53e-05	189	105	5	0c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 SHISA9 CFAP221 KCNJ16 IRX2	8.74e-05	190	105	5	3dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCell	facs-Thymus-Epithelium-24m-Epithelial\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX9 POU3F1 PTPRN NFIB IRX2	8.96e-05	191	105	5	eec14997d2bfc7e6b5a601afc43a147f6b96d668
ToppCell	facs-Thymus-Epithelium-24m-Epithelial-TECs\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX9 POU3F1 PTPRN NFIB IRX2	8.96e-05	191	105	5	1730ec5dc1cfd2f0cba7e21555641c7bce97e09d
ToppCell	Myeloid-Myeloid-B_(Activated_Macrophage)\|Myeloid / shred on cell class and cell subclass (v4)	NPC1 ANPEP DHX15 SDCBP SOD2	8.96e-05	191	105	5	7bf125249af1e8bb138ed4d999fdd74b03ab2447
ToppCell	facs-Thymus-Epithelium-24m-Epithelial-epithelial_cell_of_thymus\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX9 POU3F1 PTPRN NFIB IRX2	8.96e-05	191	105	5	4b77abc68bd72c64e7062f9527fe9d9605289ceb
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THSD4 CD248 MEST NFIA SHISA3	9.18e-05	192	105	5	f053b89bfd6048c227667ff01c38df7c51d8a496
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ANPEP CD248 NFIA NFIB SHISA3	9.18e-05	192	105	5	0e7e55505bd5454d7cf952a63fdcb46ec76f1973
ToppCell	Hippocampus-Endothelial\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ANPEP CD248 SHC1 GPRC5C PLSCR2	9.18e-05	192	105	5	36deadab892d3e639a71f33697bb2d3cbbaa5372
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD8-Trm/em_CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	TBX21 EOMES LAT OASL FYN	9.18e-05	192	105	5	7a122505d7adf236e0cbd9bcbc98e7c537600ca3
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-oRG-34\|World / Primary Cells by Cluster	SOX9 MYO10 TFAP2C NFIA SDCBP	9.41e-05	193	105	5	d55f792eb3db10452347681131e07e041348fd89
ToppCell	facs-Skin-Anagen-3m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX9 FLNB SPART NFIB SDCBP	9.41e-05	193	105	5	eba3c70701b051bc1ed1f4db9270cb27a77ffc3e
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	THSD4 POU3F1 PTPRS NFIB KCNJ16	9.41e-05	193	105	5	739fb2a57772a800a2e94bdd6c71285bb2c162a7
ToppCell	background-Cholangiocytes\|background / Sample and Cell Type and Tumor Cluster (all cells)	SOX9 LGALS4 SHISA9 CFAP221 KCNJ16	9.41e-05	193	105	5	9152241073dbe02ac2c11d86bec9b5b529196f6e
ToppCell	10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma-myofibroblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	THSD4 SOX9 MEST NFIB RBM24	9.41e-05	193	105	5	02dfd1df1e7fc84bfca2b0c95138b5b4408bb5d1
ToppCell	COVID-CD8-CD8_1\|COVID / Condition, Cell_class and T cell subcluster	TBX21 EOMES LAT OASL FYN	9.41e-05	193	105	5	221690901cb214c8ee186ff527c80dcc52d1fb1c
ToppCell	Megakaryocytic-erythropoietic-Erythro-cells-Basophilic_Erythroblast\|World / Lineage, cell class and subclass	CPA3 MEST ACSM3 NFIA GBGT1	9.64e-05	194	105	5	f054d78429364622d402ce1d9bf6ad13a1a1bf7e
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MEST NFIA PTPRS NFIB CELF3	9.64e-05	194	105	5	4e93bd903cddfd0c8f220b6a35b449895de4119b
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_OPC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYO10 CSMD3 NFIB IRX2 FYN	9.64e-05	194	105	5	920955e775617d6156c5ee8b90d2cecd01a70e12
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_Tem\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TBX21 EOMES LAT OASL FYN	9.64e-05	194	105	5	e72be6dc2711c1d4f16943c8615cf9dc2e961ff3
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-IPC_like\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	MYO10 TFAP2C EOMES MEST NFIA	9.64e-05	194	105	5	3e90be6f5b1c5c83632e62941fb18d6a627ec1b5
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SOX9 NFIA PTPRS NFIB KCNJ16	9.64e-05	194	105	5	68d15917ae222cba0ad9e716d29eebb6c5f00f69
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-J_(Lipofibroblast)\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	DSC2 DACT2 TFAP2C MEST SOD2	9.64e-05	194	105	5	784b15119c91ace33d34bfb3d68c182566a3e9a8
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_Tem\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TBX21 EOMES LAT OASL FYN	9.64e-05	194	105	5	ac03be73fdc32dacd4a450c0fb28617e043b8444
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-epithelial_progenitor_cell\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX9 MYO10 DACT2 LGALS4 HOXB9	9.64e-05	194	105	5	46e522ca59db545d1eb0c27cd4361f19d4f8f762
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_Tem-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TBX21 EOMES LAT OASL FYN	9.64e-05	194	105	5	7ab4418a8a12c488d74af3676bdac672628da80c
ToppCell	T/NK_cells-NKT_cell\|World / Lineage and Cell class	TBX21 EOMES LAT OASL FYN	9.64e-05	194	105	5	8e09989ec2d1bbfe70cb18321c2ae94e0d0d9f18
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_Tem-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TBX21 EOMES LAT OASL FYN	9.64e-05	194	105	5	760761ce7d22edf9a8cec71e8ab0caa273fce3f7
ToppCell	Multiple_Sclerosis-Lymphocyte-T_NK-CD8_TEM\|Multiple_Sclerosis / Disease, Lineage and Cell Type	TBX21 EOMES LAT OASL FYN	9.64e-05	194	105	5	fa53f1aab2f5923e90f090e10e3560b583441dc4
Drug	ethylbenzene	CYP2E1 CAT CRKL MEST SDCBP SOD2	3.22e-07	60	104	6	CID000007500
Drug	UROX	CYP2E1 CAT PTPRN SOD2	5.39e-07	15	104	4	CID000008799
Drug	Bacampicillin hydrochloride [37661-08-8]; Up 200; 8uM; MCF7; HT_HG-U133A	DENND4A DEAF1 E2F4 LGALS4 RUSC2 TBX19 NFIB OTUD4	3.72e-06	199	104	8	3273_UP
Drug	iron-EDTA	CAT PTPRN SOD2	7.62e-06	9	104	3	CID000088882
Drug	ethyl cysteinate	ANPEP CAT SOD2	7.62e-06	9	104	3	CID000003297
Drug	1-hydroxyethyl	CYP2E1 CAT SOD2	1.09e-05	10	104	3	CID000123157
Drug	Porphyrins	ANPEP CAT SOD2	1.49e-05	11	104	3	ctd:D011166
Drug	1,5-diol	CYP2E1 CAT SOD2	1.98e-05	12	104	3	CID000014116
Drug	1,2,3,5,6,7-hexahydroquinoxaline	CAT SOD2	2.07e-05	2	104	2	CID011564482
Drug	diallyldimethylammonium chloride	CAT SOD2	2.07e-05	2	104	2	ctd:C508190
Drug	Fossil Fuels	CYP2E1 SOD2	2.07e-05	2	104	2	ctd:D005579
Drug	methyleicosanoate	CAT SOD2	2.07e-05	2	104	2	CID000014259
Drug	nickel carbonate hydroxide	CAT SOD2	2.07e-05	2	104	2	CID000025559
Drug	copper benzoate	CAT SOD2	2.07e-05	2	104	2	CID000164650
Drug	S-benzoylmercaptoacetyltriglycine	CAT SOD2	2.07e-05	2	104	2	CID000185457
Drug	2-chloroethyl-3-chloropropyl sulfide	CAT SOD2	2.07e-05	2	104	2	CID000522430
Drug	4-nitrophenylglyoxylic acid	CAT SOD2	2.07e-05	2	104	2	CID000151940
Drug	NL16	CAT SOD2	2.07e-05	2	104	2	CID011847437
Drug	AC1L2L2X	CAT SOD2	2.07e-05	2	104	2	CID000022782
Drug	methacrylonitrile	CYP2E1 CAT	2.07e-05	2	104	2	ctd:C008385
Drug	lactosylphenyl Trolox	CAT SOD2	2.07e-05	2	104	2	CID000132286
Drug	Abu-mdp	CAT SOD2	2.07e-05	2	104	2	CID000171754
Drug	diethylurea	CAT SOD2	2.07e-05	2	104	2	CID000012472
Drug	ferric ammonium sulfate	CYP2E1 CAT SOD2	2.56e-05	13	104	3	CID000186086
Drug	hydroxychavicol	TBX21 CAT SOD2	2.56e-05	13	104	3	CID000070775
Drug	ampicillin-sulbactam	CD248 CAT SOD2	2.56e-05	13	104	3	CID000119561
Drug	1,2,4-benzenetriol	NPC1 CYP2E1 CAT PTPRN SOD2	2.58e-05	76	104	5	CID000010787
Drug	Fenoprofen calcium salt dihydrate [53746-45-5]; Down 200; 7.2uM; PC3; HT_HG-U133A	DSC2 AVL9 MYO10 PRDM2 FCF1 NFIB OTUD4	2.90e-05	192	104	7	4274_DN
Drug	Prednicarbate [73771-04-7]; Down 200; 8.2uM; PC3; HT_HG-U133A	RC3H2 DENND4A WDR33 TBX19 NFIB OASL LRP6	2.99e-05	193	104	7	5119_DN
Drug	ICI182,780; Down 200; 1uM; PC3; HT_HG-U133A	DEAF1 TFAP2C PRDM2 LGALS4 RUSC2 NFIB OASL	3.30e-05	196	104	7	7495_DN
Drug	Chlorphensin carbamate [886-74-8]; Down 200; 16.2uM; HL60; HG-U133A	DENND4A ILF3 SPART OASL N4BP2L2 SEC23B SOD2	3.30e-05	196	104	7	1432_DN
Drug	0393-0188; Down 200; 10uM; PC3; HT_HG-U133A	AVL9 SPART E2F4 TFAP2C RUSC2 HOXB9 SOD2	3.41e-05	197	104	7	7536_DN
Drug	N,N-dimethylaniline	FLNB CYP2E1 CAT SOD2	4.02e-05	42	104	4	CID000000949
Drug	TMPone	CYP2E1 CAT SOD2	4.97e-05	16	104	3	CID000013220
Drug	purpurogallin	CYP2E1 CAT SOD2	6.01e-05	17	104	3	CID005281571
Drug	sodium cyanamide	CAT SOD2	6.18e-05	3	104	2	CID003015093
Drug	Glyco-SNAP-2	CAT SOD2	6.18e-05	3	104	2	CID003413551
Drug	NAPSQI	CAT SOD2	6.18e-05	3	104	2	CID000135828
Drug	2-(N-ethylperfluorooctanesulfonamido)ethyl alcohol	CAT SOD2	6.18e-05	3	104	2	ctd:C435127
Drug	2-nitro-4'-hydroxydiphenylamine	CAT SOD2	6.18e-05	3	104	2	CID003846708
Drug	copper-EDTA complex	CAT SOD2	6.18e-05	3	104	2	CID000041091
Drug	N-hydroxypyridine-4-thione	CAT SOD2	6.18e-05	3	104	2	CID000127774
Drug	2-tert-butyl-4-methylphenol	CAT SOD2	6.18e-05	3	104	2	ctd:C054527
Drug	jionoside D	CAT SOD2	6.18e-05	3	104	2	CID009895632
Drug	MAR-99	CAT SOD2	6.18e-05	3	104	2	CID000127154
Drug	laminaran	CAT SOD2	6.18e-05	3	104	2	ctd:C008247
Drug	4,7-dibromobenzofurazan	CAT SOD2	6.18e-05	3	104	2	CID000179636
Drug	copper benzochlorin	CAT SOD2	6.18e-05	3	104	2	CID000164462
Drug	3-dimethylaminophenol	CAT SOD2	6.18e-05	3	104	2	CID000007421
Drug	benzenedisulfonic acid	CAT SOD2	6.18e-05	3	104	2	CID000082621
Drug	new methylene blue	CAT SOD2	6.18e-05	3	104	2	CID000073518
Drug	4-(hydroxymethyl)benzenediazonium	CAT SOD2	6.18e-05	3	104	2	CID000122997
Drug	2-chloroethyl 4-chlorobutyl sulfide	CAT SOD2	6.18e-05	3	104	2	CID000528233
Drug	C3decaynol	CAT SOD2	6.18e-05	3	104	2	CID006436939
Drug	4,7-dimethylbenzofurazan	CAT SOD2	6.18e-05	3	104	2	CID000181529
Drug	anthracene	DSC2 CAT DNAH9 SOD2	6.30e-05	47	104	4	CID000008418
Drug	NSC-277174	CD248 CAT FAT2 SOD2	6.85e-05	48	104	4	CID000002171
Drug	o-xylene	CYP2E1 CAT SDCBP SOD2	6.85e-05	48	104	4	CID000007237
Drug	vanadyl	PDE2A SHC1 CAT CRKL PTPRS LRP6 FYN DNAH9	8.38e-05	307	104	8	CID000061671
Drug	HepI	ANPEP CAT SOD2	9.97e-05	20	104	3	CID003036968
Drug	Thioridazine hydrochloride [130-61-0]; Up 200; 9.8uM; MCF7; HT_HG-U133A	NPC1 SOX9 OASL N4BP2L2 FYN CLCF1	1.01e-04	162	104	6	1486_UP
Drug	itraconazole oral solution	CYP2E1 CAT SC5D NFIA NFIB	1.01e-04	101	104	5	CID000003793
Drug	ciprofloxacin	CYP2E1 CD248 CAT SDCBP SOD2	1.01e-04	101	104	5	CID000002764
Drug	resorufin	CYP2E1 FCF1 PTPRN SOD2	1.01e-04	53	104	4	CID000069462
Drug	Fenton's reagent	CAT TNN SOD2	1.16e-04	21	104	3	CID000160257
Drug	aminoacetonitrile	ANPEP CYP2E1 CAT	1.16e-04	21	104	3	CID000010901
Drug	SC-45662	CAT SOD2	1.23e-04	4	104	2	CID005487420
Drug	diosbulbin B	CAT SOD2	1.23e-04	4	104	2	ctd:C569454
Drug	satranidazole	CAT SOD2	1.23e-04	4	104	2	CID000041841
Drug	Aniten	CAT SOD2	1.23e-04	4	104	2	CID000040815
Drug	querglanin	CAT SOD2	1.23e-04	4	104	2	CID000188923
Drug	isoquerglanin	CAT SOD2	1.23e-04	4	104	2	CID000188924
Drug	AC1L43WF	CAT SOD2	1.23e-04	4	104	2	CID000150216
Drug	4-methylthiobenzate	CAT SOD2	1.23e-04	4	104	2	CID011815952
Drug	1,4-naphthoquinone-2-sulfonate	CAT SOD2	1.23e-04	4	104	2	CID000092470
Drug	NSC-95411	CAT SOD2	1.23e-04	4	104	2	CID000066823
Drug	cyclohexa-2,4-dien-1-ol	CAT SOD2	1.23e-04	4	104	2	CID000192872
Drug	AC1MHZUY	CAT SOD2	1.23e-04	4	104	2	CID003035720
Drug	Me2TU dioxide	CAT SOD2	1.23e-04	4	104	2	CID000128040
Drug	zinc picolinate	CAT SOD2	1.23e-04	4	104	2	CID009904746
Drug	4-chloro-2,6-dimethylphenol	CAT SOD2	1.23e-04	4	104	2	CID000070747
Drug	AH18	CAT SOD2	1.23e-04	4	104	2	CID005316885
Drug	7-I2	CAT SOD2	1.23e-04	4	104	2	CID000001894
Drug	2,5-dimethoxyhydroquinone	CAT SOD2	1.23e-04	4	104	2	CID000097641
Drug	Tuftsin-m	CAT SOD2	1.23e-04	4	104	2	CID000146819
Drug	5-diazouracil	CAT SOD2	1.23e-04	4	104	2	CID000024327
Drug	Tyr-tyr-phe	CAT SOD2	1.23e-04	4	104	2	CID000130070
Drug	pyridoxal thiosemicarbazone	CAT SOD2	1.23e-04	4	104	2	CID005355931
Drug	dltp	ANPEP CAT FCF1 SOD2	1.26e-04	56	104	4	CID000031250
Drug	4-vinyl-1-cyclohexene dioxide	CYP2E1 SHC1 CAT CRKL NFIA SOD2	1.32e-04	170	104	6	ctd:C012606
Drug	p0e	SHC1 CAT SOD2	1.53e-04	23	104	3	CID004369442
Drug	AlPc	CAT APOH SOD2	1.53e-04	23	104	3	CID000123667
Drug	cyanuric chloride	CYP2E1 MEST SOD2	1.53e-04	23	104	3	CID000007954
Drug	AC1L1ICV	CAT LGALS4 SOD2	1.53e-04	23	104	3	CID000004522
Drug	dimercaptosuccinic acid	ANPEP CAT SOD2	1.53e-04	23	104	3	CID000009354
Drug	AC1L1AUK	CAT APOH SOD2	1.98e-04	25	104	3	CID000001154
Drug	POBN	CYP2E1 CAT SOD2	1.98e-04	25	104	3	CID000092375
Drug	Niacinamide	SOX9 CYP2E1 SHC1 CAT SOD2	2.02e-04	117	104	5	ctd:D009536
Drug	croconic acid	CAT SOD2	2.05e-04	5	104	2	CID000546874
Drug	oxodihydrothiochrome	CAT SOD2	2.05e-04	5	104	2	CID000196353
Disease	Bladder Neoplasm	ANPEP PRDM2 EOMES LIG1 KMT2D SOD2	1.12e-05	140	105	6	C0005695
Disease	Malignant neoplasm of urinary bladder	ANPEP PRDM2 EOMES LIG1 KMT2D SOD2	1.17e-05	141	105	6	C0005684
Disease	retinitis pigmentosa (implicated_via_orthology)	DACT2 EPG5 USH2A	1.20e-04	27	105	3	DOID:10584 (implicated_via_orthology)
Disease	Bonnevie-Ullrich Syndrome	CAT SOD2	1.25e-04	5	105	2	C1527168
Disease	Turner Syndrome	CAT SOD2	1.25e-04	5	105	2	C0041408
Disease	Gonadal Dysgenesis, 45,X	CAT SOD2	1.25e-04	5	105	2	C0242526
Disease	thyroid stimulating hormone measurement	SOX9 DACT2 APOH DHX15 PIGT NFIA PTPRS	1.61e-04	323	105	7	EFO_0004748
Disease	Liver Cirrhosis, Alcoholic	CYP2E1 CAT SOD2	1.66e-04	30	105	3	C0023891
Disease	Asphyxia Neonatorum	CAT SOD2	1.86e-04	6	105	2	C0004045
Disease	Aortic Diseases	CAT SOD2	1.86e-04	6	105	2	C0003493
Disease	Major Depressive Disorder	SOX9 DEAF1 ANPEP TBX21 CAT SOD2	2.39e-04	243	105	6	C1269683
Disease	alcoholic liver cirrhosis (is_implicated_in)	CYP2E1 SOD2	2.60e-04	7	105	2	DOID:14018 (is_implicated_in)
Disease	optic neuritis (is_implicated_in)	CAT SOD2	3.46e-04	8	105	2	DOID:1210 (is_implicated_in)
Disease	sensorineural hearing loss (biomarker_via_orthology)	CAT SOD2	3.46e-04	8	105	2	DOID:10003 (biomarker_via_orthology)
Disease	Malignant neoplasm of breast	FLNB PDE2A LRRC37A2 CAT CFHR5 EPG5 EOMES HOXB9 KMT2D LRRC37A DNAH9 SOD2	4.42e-04	1074	105	12	C0006142
Disease	pseudoxanthoma elasticum (is_implicated_in)	CAT SOD2	4.44e-04	9	105	2	DOID:2738 (is_implicated_in)
Disease	Marfan Syndrome, Type I	CAT SOD2	4.44e-04	9	105	2	C4721845
Disease	Hyperthyroidism	CAT SOD2	4.44e-04	9	105	2	C0020550
Disease	Primary Hyperthyroidism	CAT SOD2	4.44e-04	9	105	2	C3714618
Disease	bronchopulmonary dysplasia	DSC2 STXBP5 CSMD3	5.57e-04	45	105	3	MONDO_0019091
Disease	Premature Birth	CAT SOD2	6.76e-04	11	105	2	C0151526
Disease	Marfan Syndrome	CAT SOD2	6.76e-04	11	105	2	C0024796
Disease	colon carcinoma (is_marker_for)	CRKL KMT2D	9.54e-04	13	105	2	DOID:1520 (is_marker_for)
Disease	Diffuse Large B-Cell Lymphoma	CAT KMT2D SOD2	1.00e-03	55	105	3	C0079744
Disease	Necrosis	CYP2E1 CAT SOD2	1.00e-03	55	105	3	C0027540
Disease	cardiotoxicity, response to anthracycline-based chemotherapy	ILF3 SHISA3	1.11e-03	14	105	2	EFO_0005257, EFO_1001482
Disease	Cardiomyopathies	DSC2 CAT EPG5 SOD2	1.22e-03	130	105	4	C0878544
Disease	inherited metabolic disorder (is_implicated_in)	TBX19 LIG1	1.28e-03	15	105	2	DOID:655 (is_implicated_in)
Disease	Alcohol abuse	CYP2E1 TBX19 FYN	1.78e-03	67	105	3	C0085762
Disease	cystitis (biomarker_via_orthology)	CAT SOD2	1.85e-03	18	105	2	DOID:1679 (biomarker_via_orthology)
Disease	Cardiomyopathies, Primary	CAT EPG5 SOD2	1.93e-03	69	105	3	C0033141
Disease	Myocardial Diseases, Secondary	CAT EPG5 SOD2	1.93e-03	69	105	3	C0036529
Disease	familial hyperlipidemia (biomarker_via_orthology)	CYP2E1 SHC1	2.06e-03	19	105	2	DOID:1168 (biomarker_via_orthology)
Disease	Liver diseases	NPC1 LAT SC5D	2.19e-03	72	105	3	C0023895
Disease	Liver Dysfunction	NPC1 LAT SC5D	2.19e-03	72	105	3	C0086565
Disease	response to heparin, antibody measurement	SC5D RBM24	2.29e-03	20	105	2	EFO_0004556, EFO_0006816
Disease	Unipolar Depression	SOX9 DEAF1 ANPEP TBX21 CAT	2.37e-03	259	105	5	C0041696
Disease	DNA methylation	WDR7 DHX15 MDN1 NFIA PTPRS RBM24 FYN USH2A	2.41e-03	656	105	8	GO_0006306
Disease	vitiligo (is_implicated_in)	CAT SOD2	2.52e-03	21	105	2	DOID:12306 (is_implicated_in)
Disease	Mammary Carcinoma, Human	PDE2A LRRC37A2 CAT HOXB9 KMT2D LRRC37A SOD2	2.76e-03	525	105	7	C4704874
Disease	Mammary Neoplasms, Human	PDE2A LRRC37A2 CAT HOXB9 KMT2D LRRC37A SOD2	2.76e-03	525	105	7	C1257931
Disease	Mammary Neoplasms	PDE2A LRRC37A2 CAT HOXB9 KMT2D LRRC37A SOD2	2.82e-03	527	105	7	C1458155
Disease	Breast Carcinoma	PDE2A LRRC37A2 CAT HOXB9 KMT2D LRRC37A SOD2	3.16e-03	538	105	7	C0678222
Disease	Cardiomegaly	CYP2E1 SHC1 SOD2	3.16e-03	82	105	3	C0018800
Disease	Cardiac Hypertrophy	CYP2E1 SHC1 SOD2	3.16e-03	82	105	3	C1383860
Disease	complement factor H-related protein 3 measurement	CFHR5 PIGT USH2A SHISA3	3.17e-03	169	105	4	EFO_0600056
Disease	Drug-Induced Liver Disease	DSC2 CYP2E1 SHC1 CAT APOH SOD2	3.27e-03	404	105	6	C0860207
Disease	Drug-Induced Acute Liver Injury	DSC2 CYP2E1 SHC1 CAT APOH SOD2	3.27e-03	404	105	6	C3658290
Disease	Hepatitis, Toxic	DSC2 CYP2E1 SHC1 CAT APOH SOD2	3.27e-03	404	105	6	C0019193
Disease	Chemically-Induced Liver Toxicity	DSC2 CYP2E1 SHC1 CAT APOH SOD2	3.27e-03	404	105	6	C4279912
Disease	Chemical and Drug Induced Liver Injury	DSC2 CYP2E1 SHC1 CAT APOH SOD2	3.27e-03	404	105	6	C4277682
Disease	Hepatitis, Drug-Induced	DSC2 CYP2E1 SHC1 CAT APOH SOD2	3.27e-03	404	105	6	C1262760

Protein segments in the cluster

Peptide	Gene	Start	Entry
EPFVIYLGLNLPHPY	ARSK	196	Q6UWY0
QTSHALGYYPDPTFP	EOMES	556	O95936
FLLYLHRPGPQYGLP	EPG5	1316	Q9HCE0
YQHPPEYGAARPAQD	AMOT	281	Q4VCS5
DALYPNGVHPYPAQS	CELF3	296	Q5SZQ8
PDNGFVNYPAKPTLY	APOH	211	P02749
LSHTGVAEYQPPPYF	TFAP2C	46	Q92754
GQVLSPGYPAPYEHN	CSMD2	1281	Q7Z408
ILSPGYPFPYDNNLR	CSMD3	1426	Q7Z407
LGPNYLHIPVNCPYR	CAT	366	P04040
AANYPDLPSAYQPGI	CD248	486	Q9HCU0
HYDTPYPLPKSDQIG	ANPEP	331	P15144
PLELGYQNFLYPSEP	CCDC22	81	O60826
NPFTNLPHTPRYYDI	DHX15	116	O43143
SYQNDPPFGSYVVPI	DSC2	636	Q02487
PPLQYSYNGFPVLRN	DENND4A	691	Q7Z401
IQQPGPYFSHPAIRY	NFIA	376	Q12857
VPVYPPHSENIQYFQ	RC3H2	586	Q9HBD1
IQRPFGIPAHYVYPQ	RBM24	111	Q9BX46
GIPAHYVYPQAFVQP	RBM24	116	Q9BX46
GVNFPIGEIPSQPYY	NFIB	236	O00712
QTLSLYQDPLYPGFP	OTUD4	656	Q01804
YDPTTALQNGFYPAP	RBMS2	251	Q15434
ALQNGFYPAPYNITP	RBMS2	256	Q15434
QLYNNFPSFLHYLPG	CYP2E1	216	P05181
AVYPQATQTYGLPPF	EYA3	106	Q99504
LYPFPVHLYLQPGTS	IQCM	166	A0A1B0GVH7
VNGNPFYEYGHRLPL	LGALS4	116	P56470
YEPALLQPYLFHQFG	PTPRN	201	Q16849
SVQPPGEDQAYYHLP	LRRC37A3	281	O60309
GPYDFYQHPNVPEAR	MDN1	3711	Q9NU22
SVQPPGEDQAYYHLP	LRRC37A2	281	A6NM11
SVQPPGEDQAYYHLP	LRRC37A	281	A6NMS7
YHHPENIQLPPGYQP	INTS1	711	Q8N201
YHNPGYLVVLPDSTP	LAT	156	O43561
HPPLIPYTDFYNSTL	HECTD2	331	Q5U5R9
HIPESPLQFYVNYPN	FLNB	1806	O75369
FYPGRQHDYLVPPAG	PLSCR2	41	Q9NRY7
PYFYSQIRGFHLPPS	FAT2	341	Q9NYQ8
LNIPDAYAHPLFYRG	PDE2A	476	O00408
ASVNPYQPIAGLYEP	MYO10	101	Q9HD67
HQPQPLGLYAQAAYP	POU3F1	151	Q03052
DLPHPFGLTQYQDYI	LRP6	831	O75581
NSYGIPEPAHAYAQP	CRKL	196	P46109
HPYGSAAYPYQLNDP	IRX2	101	Q9BZI1
RGYPDFNLIVNPYEP	OASL	361	Q15646
YLPDGQSPVPVQSYF	PTPRS	1141	Q13332
SGSLPSVYHPYIQPQ	HOXB9	71	P17482
SVYHPYIQPQGVPPA	HOXB9	76	P17482
HVPPGCSQGLNPLYY	GPRC5C	26	Q9NQ84
DKHIYQPYPSGADVP	NPC1	416	O15118
YGNPQYLPLDEAHPT	GALE	136	Q14376
DALAAPYVLYPGFQP	CEFIP	1326	Q711Q0
LHSIFQYPNPAVSYP	HEATR5A	1876	Q86XA9
LFPYGYTSKLPPNHE	CPA3	311	P15088
EVYPYPSPLHAVALQ	DACT2	271	Q5SW24
LRLSPPPGDHDYIYN	E2F4	381	Q16254
REYLNPLHYTGPPTE	BTAF1	1351	O14981
AIHPSYYAVPRQQFP	GBGT1	226	Q8N5D6
FFQYNTQLGPPYHIL	FCF1	56	Q9Y324
EPHYPGYQDSCQIAP	DEAF1	391	O75398
PQHYPSFGVTSIPNY	FYN	36	P06241
YLPFLALPDGAHNYQ	AVL9	56	Q8NBF6
FPLLAPPTNYGLYEQ	CFAP107	131	Q8N1D5
YYQGDNYNSPVPPKH	ILF3	716	Q12906
PENAQGRHPYAYVPF	CYP4V2	446	Q6ZWL3
EYGYVQPSVPPYQHG	CFHR5	276	Q9BXR6
PESPYLYGLHPNAEI	DNAH9	4171	Q9NYC9
YYENFFHPQGVPSPQ	FOXI1	31	Q12951
AVVPGPAEHPLQYNY	EIF4E2	46	O60573
LDPSGYNPAKNNYHP	LIG1	261	P18858
SAPIPHDGNLYPRLY	SDCBP	36	O00560
IHFIYGPLDPVNPYP	MEST	276	Q5EB52
YDYSTAHQPGPNAPL	CHID1	261	Q9BWS9
LNQHYPSFKPPPFQY	PRDM2	1291	Q13029
DYDPLYVFNPNPGLF	CFAP221	651	Q4G0U5
DPGPSQPSEYYLFQK	RUSC2	436	Q8N2Y8
ILTPGPNYRPGYNNF	USH2A	456	O75445
RNYPYPQLHFLALQG	RNF165	211	Q6ZSG1
FVGLSHQYPGPYFLA	SAMD9L	1416	Q8IVG5
PQNPYYYVDGDPHFI	ITIH3	641	Q06033
YFAYPLQQEPPLPGK	SHISA3	216	A0PJX4
PHSYPNLGQISNPYE	SHISA9	251	B4DS77
FPPQYLSSEITLHPY	SECISBP2	76	Q96T21
TLPLGFPYAVSPYFH	SAMD11	506	Q96NU1
QQIAYSPFNLPHYSP	SOX9	416	P48436
NGYPIFENPYPLSIH	STXBP5	381	Q5T5C0
IQPILYSYSFHGPPE	SEC23B	621	Q15437
YSYSFHGPPEPVLLD	SEC23B	626	Q15437
EYPPSSNYIRGYNHP	STARD6	136	P59095
PNRPFGLFTHYVDNP	ACSM3	431	Q53FZ2
YLNYLGPPFNEPDFN	CLCF1	61	Q9UBD9
SHAALLEPYFPQEPY	C11orf53	51	Q8IXP5
PPAYTPQAAEGHYTV	SPART	171	Q8N0X7
YRPTPLQHYIFPAGG	MTREX	311	P42285
YTPDPNHGFYVSPSV	PIGT	456	Q969N2
PSAQIHGYILTYQFP	TNN	996	Q9UQP3
INADAKYPGYPPEHI	KCNJ16	11	Q9NPI9
GHPQPFFYSLQSLRP	WDFY4	2841	Q6ZS81
LPYDYGALEPHINAQ	SOD2	31	P04179
VGEDHYFRSPPPYDQ	TBX4	361	P57082
AIQPDAGYYNDLVPP	WDR33	81	Q9C0J8
PIYQLPLTHDQGYPA	THSD4	241	Q6ZMP0
NYQYAAPLPLPAPHT	TBX19	261	O60806
QSLPYHIYPFIFPLH	SC5D	176	O75845
VQFHRPNYGAIPYPD	SLC6A14	546	Q9UN76
APYLPQYIDHVISPG	WDR7	1051	Q9Y4E6
DHQYYNDFPGKEPPL	SHC1	346	P29353
PQHRYFYPEPGAQDA	TBX21	31	Q9UL17
GGDHYSPLLPNQYPV	TBX21	351	Q9UL17
QAFYQRAPYPGSLPL	KMT2D	2796	O14686
VPYGPPLPSLNYHLN	N4BP2L2	276	Q92802
NYLPVHLQGFEPPGY	MYOG	21	P15173